DDB0230133

Species: Slime mold
Alias: DdisK245, DDB0230133
External Links: DictyBase Link ,
Annotation:

Classification

Group: TKL
Family: TKL-Unique

Sequence

Name Sequence Type Origin Length Description Download
DDB0230133.AA Protein None 1090 None Fasta, JSON
DDB0230133.kin_dom Protein Kinase Domain None 248 None Fasta, JSON

Protein domain

Protein domains of DDB0230133.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DDB0230133.AA TKL-Unique 194-443 39 3.9e-129 435.3 In-house 1-290 (290) Show / Hide
Range on Protein: 194-443
Range on HMM: 1-290/290
Sequence Identity: 39% (114 aa)

IGNVIGGGGYGAIYKAKWRGLSVAVKVISELSDGS-EFEKELEMHK---ELLH-HPNIVHFVGFCV----SPK--CLVLEYIEGGSLDKYLH--------
..|.||.||||..||.|||| .||.|......| | |...|.|...   . || ||||||..|.|.    .|.  |.|.||..||||...||        
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

-NPNYTFSPQLRLKMANDIAKGMCFLHRNE--ILHLDLKPQNFLVVSISPEAPVSIKLADFGLATSSSRS---FYG-------PTVEGSFLYMSPEVFTQ
 |.|.....|.|.|||.|||.||..||..|  |.|.|||..||||.. |..|...||..||||....|..   ...       .|..|||..|.|||...
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

--KKFSRAADVWSYGACLIEILTNKR------PYQEYDQLGYLELARVREEGLPPMIPPEIEGDLRKIIEACFHRDHTKRPNFENIEQFL
  ...|. .||.|.|..|.||.|.|.      |||..|| ...|.....||...|.||.... ..|..|..|.|.|...||.|..|   |
NFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL

Kinase DDB0230133.AA TKL 198-443 27 4e-88 299.08 In-house 1-364 (364) Show / Hide
Range on Protein: 198-443
Range on HMM: 1-364/364
Sequence Identity: 27% (103 aa)

IGGGGYGAIYKAKWRG----------LSVAVKVISELSDGS----------------------------EFEKELEMHKELLHHPNIVHFVG--------
|| ||.| .||.||||            ||||.... .| .                            .||.|  |..  |.|||||.|.|        
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-FCVSP------KCLVLEYIEGGSLDKYLHNPNYTFSPQLRLKMANDIAKGMCFLHRNE--------ILHLDLKPQNFLVVSI---------SPEAPVSI
 .|..|       |.| ||..||||  |||       ...|...| |||.||..|| ..        |.| |||..| || .          .| |.. .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KLADFGLATSSSRSFY--------------------GPTVEGSFLYMSPEVFTQK----------------KFSRAADVWSYGACLIEILTNKRPYQEYD
|..||||... |.|.                       |. |.. .|.|||. ..                ..| ..||.|.| .| |||| .|||..|.
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

QLGYL-------ELARVREEGLPPMIP------------PEIEGDLRKIIEACFHRDHTKRPNFENIEQFL
    .       ... | ..||.| ||            | .  ...|... | . | .|||.|. | . |
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase DDB0230133.AA LRRK 192-445 27 4.5e-63 215.85 In-house 1-351 (351) Show / Hide
Range on Protein: 192-445
Range on HMM: 1-351/351
Sequence Identity: 27% (96 aa)

LEIGNVIGGGGYG-AIYKAKWRG----------------------------LSVAVKVISE----------LSDG-------------------------
|.|.. || ||.|  .|.|||||                             .||.|..             |..                         
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

-SEFEKELEMHKELLHHPNIVHFVGFCVSPKCLVLEYIEGGSLDKYLHNPN-YT-------FSPQLRLKMANDIAKGMCFLHRNE--ILHLDLKPQNFLV
 .|| .|. .  . |.|||||  .||| .| |.|.||.  |.|...|||.  .        .|..|.|| | .||||| .||..   |.| |||. | |.
FREFRHEVWIMSH-LNHPNIVSLKGFCIHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILL

VSIS-------PEAPVSIKLADFGLAT--SSSRSFYGPTVEGSFLYMSPEVFT---QKKFSRAADVWSYGACLIEILTNK-RPYQEYDQLGYLELARVRE
 |..       |.|.| .|.||||. .  .. ..   ....| ...|.||.      . ..  .|. |.|  | |.|| . .|..|.|  . ...    |
WSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIE

E----GLPPMIPPE-IEG-----DLRKIIEACFHRDHTKRPNFENIEQFLDA
.    ||.| ||..   .     .. . |. | . | .||| |. | ..|  
DKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ

Kinase DDB0230133.AA S_TKc 192-451 25 1.1e-57 198.81 SMART 1-231 (231) Show / Hide
Range on Protein: 192-451
Range on HMM: 1-231/231
Sequence Identity: 25% (69 aa)

LEIGNVIGGGGYGAIYKAKWRG--LSVAVKVISELSDGSEFEKELEMHKELLHHPNIVHFVGFCV-SPKCLVLEYIEG--GSLDKYLHNPNY-----TFS
 ||...|| |..|  ||.....    ||.|.|.       ...|....|.  ||||||.. .... .  ..|.||..|  |.| .|... ..      |.
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK--HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFP

PQLRLKMANDIAKGMCFLHRNEILHLDLKPQNFLVVSISPEAPVSIKLADFGLATSSSRSFYGPTVEGSFLYMSPEVFTQKKFSR-AADVWSYGACLIEI
.    ...  |.... ..|.. |.| ||||.| |. .        ||..|||||.         |. |.  ||.|||.   .... ..|.|| | .|.| 
E-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

LTNKRPYQEYDQLGYLELARVREEGLPPMIPPEIEGDLRKIIEACFHRDHTKRPNFENIEQ-FLDAMTDSLF
|. . |..  ..   ... .                ... .|. |...| .|||    . |  .|.. .  |
LCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase DDB0230133.AA MLK 192-443 30 6.7e-52 178.31 In-house 1-291 (291) Show / Hide
Range on Protein: 192-443
Range on HMM: 1-291/291
Sequence Identity: 30% (89 aa)

LEIGNVIGGGGYGAIYKAKWRGLS-----VAVKVIS--------ELSDGSEFEKELEMHKELLHHPN----IVHFVGFCVSP-K--CLVLEYIEGGSLDK
...  .|| |..|. .|..||.       |||| .         . .   .||.|  .|   | |||    |. |.| | .| .  |.|.||.|||||  
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMEC-RHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

YLHNPN-------------YTFSPQLRLKMANDIAKGMCFLHRNE---ILHLDLKPQNFLVVS--ISPEAPVSIKLADFGLATSSSRSFY-GPTVEGSFL
.||. .              . .... .. | ..|.|| .|| ..   | | |||..| |.      . .    | .|||.... ...    .   |.. 
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICH-DMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYA

YMSPEVFTQ---KKFSRAADVWSYGACLIEILTNKRPYQ-EYDQLGYLELARVREEGLPPMIPPEIEGDLRKIIEACFHRDHTKRPNFENIEQFL
.|.|||..|    |.|...||||.| .| |.|| . ||. .||..    .. | ..|| | ||...   . | .. | . |  |||.|  | |.|
WMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPM--AIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL

Kinase DDB0230133.AA Pkinase 192-446 26 7.5e-52 183.38 Pfam 1-293 (293) Show / Hide
Range on Protein: 192-446
Range on HMM: 1-293/293
Sequence Identity: 26% (80 aa)

LEIGNVIGGGGYGAIYKAKWRGLS--VAVKVISELSDGSEFEK------ELEMHKELLHHPNIVHFVGFCVSPK--CLVLEYIEGG----SLDKYLH---
..|| .|| |..|  ||....| .  ||||.|.  .. |....      |....|.| .||||| . ... ...  ..|.|| |||    .|  |..   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

NPNYTFSPQLRLKMANDIAKGMCFLHRNEILHLDLKPQNFLVV-SISPEAPVSIKLADFGLA----TSSSRSFYGPTVEGSFLYMSPEVFT-QKKFSRAA
. ...||..   ...  |..|. ..|.. |.| ||||.|.|..    ..|  ..|..|||||    . ... ..  |. |.  ||.|||   ... ....
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA--CVKICDFGLAKQFDY-NNS-MT--TFCGTPWYMAPEVIRGGQYYGPKV

DVWSYGACLIEILTNKRPYQEY------DQLGYLELARVREEGLPPMIPPEIE-------------------GDLRKIIEACFHRDHTKRPNFENIEQFL
|.||.|  |.| |. . |...       ||.    ..|...  |.  .| ...                    .....|. |...| .|||.   .|| |
DMWSCGCILYEMLCGRPPFPGHCWHDNHDQM--QMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT---AEQIL

DA--M
    .
QHPWF

Kinase DDB0230133.AA Dicty4 192-445 32 2.5e-51 169.52 In-house 1-277 (277) Show / Hide
Range on Protein: 192-445
Range on HMM: 1-277/277
Sequence Identity: 32% (92 aa)

LEIGNVIGGGGYGAIYKAKWRGLSVAVKVISELSDG------SEFEKELEMHKELLHHPNIVHFVGFCV----SP--KCLVLEYIEGGSLDKYLHN----
. |.. ||.|..|  ||..|||  ||||.   . ..      .|| || .  .  . ||||. | | |      |   | | ||   |.| . ||.    
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMC-KIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSE

--PNYTFSPQLRLK---MANDIAKGMCFLHR-N-EILHLDLKPQNFLVVSISPEAPVSIKLADFGLAT----SSSRSFYGPTVEGSFLYMSPEVFTQKKF
  .. . .  |...   || |.|.||  ||  |  |.|.|||. | ||      .   .| .||||..     .. ..   |. |. ..|.|||   . .
QQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLV-----DKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPY

SRAADVWSYGACLIEILTNKRPYQ-EYDQLGYLELARVREEGLPPMIPPEIEGDLRKIIEACFHRDHTKRPNFENIEQF--LDA
  .||| |.|  | |||| . ||| ... .  .  | | ...| | ||.     ... |. | . | ..|| || | |   |..
NEKADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRA-VCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH

Kinase DDB0230133.AA TK 192-443 17 3.7e-49 162.53 In-house 1-486 (486) Show / Hide
Range on Protein: 192-443
Range on HMM: 1-486/486
Sequence Identity: 17% (83 aa)

LEIGNVIGGGGYG---AIYKAKWRGL---------------------------SVAVKVISELSDGSEFE-------------------KELEMHKE-LL
...|...| | .|    .||..|||.                            ||||.. | .. |. |                    |..| .. |.
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

HHPNIVHFVGFCVSPK--------------CLVLEYIEGGS----LDKYLHNPNYT--------------------------------------------
||||||...| |. ..              ..|.|| ..|.    |..||..   .                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------FSPQLRLKMANDIAKGMCFLHRN------EILHLDLKPQNFLVVSISP------EAPVSIKLADFG---
                               .... .| |. .||.|| .||..       . | ||   | || .  .      . .  .|.||||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LATSSSRSFYGPTVE------------------------GSFL---YMSPEVFT---------QKKFSRAADVWSYGACLIEILT-NKRPYQEYD
     ||    .. .  ...                        |  |   .|.||...          .||. . ||||.| .. ||.|  . || .. 
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

Q----------LGYLELARVR-----------EEGLPPMIPPEIE--------------GDLRKIIEACFHRDHTKRPNFENIEQFL
              .|. |             ......  ||                  ..  ..  |.|.|  .||.|. . ..|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase DDB0230133.AA STE 192-437 21 5.3e-48 165.8 In-house 1-349 (359) Show / Hide
Range on Protein: 192-437
Range on HMM: 1-349/359
Sequence Identity: 21% (77 aa)

LEIGNVIGGGGYGAIYKAKWR-----------------GLSVAVKVIS----------------ELSDGSEFE---KELEMHKELLH-HPNIVHFVGFCV
.|.  .|| |..|  |||. .                 |  .|.|...                | .. .|..   ||....|.. | |||||.. | ..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

SP---------KCLVLEYIEGGSLDKYLH-------NPN------YTFSPQLRLKMANDIAKG-MCFLHRNEILHLDLKPQNFLVVSISPEAPVSIKLAD
            ....||..|||||. ..       . |       .|. ..  ... .| || . .||.. | | |.||.| |.          .||.|
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL----------VKLCD

FGLATSSSRSFY----------------GP-TVEGSFLYMSPEVFTQ------KKFSRAADVWSYGACLIEILTNKRPYQEYDQLGYLELAR--VREE--
||.... . |                     |. |.  .|.||| .|      |. .. .|.|| | ..|| .| | |. ..  .  . ..    . .  
FGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQ

--------GLPPMIPPEIE-------------------GDLRKIIEACFHRDHTKRPNFE
        | || .|....                    ...  |. |. .|  |||. .
FEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTAS

Kinase DDB0230133.AA Pkinase_Tyr 192-443 28 3.3e-45 153.71 Pfam 1-270 (270) Show / Hide
Range on Protein: 192-443
Range on HMM: 1-270/270
Sequence Identity: 28% (80 aa)

LEIGNVIGGGGYGAIYKAKWR------GLSVAVKVISELSDGSE-----FEKELEMHKELLHHPNIVHFVGFCV---SP--KCLVLEYIEGGSLDKYLHN
...| ..| | .| .||..|.      .. ||||.. | .. ..     | .|... |.| |||||| ..| |.    |   ..|.|| ..|.|..||..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

P---NYTFSPQLRLKMANDIAKGMCFLHRNEILHLDLKPQNFLVVSISPEAPVSIKLADFGLATSS-SRSFYGPTVEG----SFLYMSPEVFTQKKFSRA
.   .  ....  |.|. .||||| .|... . | ||   | || .     .  .| .|||||    . . |  .. |        |.||..  .||. .
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE-----NNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTK

ADVWSYGACLIEILT-NKRP-YQEYDQLGYLELARVREEGLPPMIPPEIEGDLRKIIEACFHRDHTKRPNFENIEQFL
 ||||.| .. ||.|  . | |..     .  .... |.|    .|.    .. ...  | | |  .|| |. | ..|
SDVWSFGVLMWEIFTYGEQPTYPGM--SNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL

Kinase DDB0230133.AA LISK 197-386 29 1.8e-42 135.65 In-house 1-238 (296) Show / Hide
Range on Protein: 197-386
Range on HMM: 1-238/296
Sequence Identity: 29% (71 aa)

VIGGGGYGAIYKAKWR--GLSVAVKVISE-------LSDGSEFEKELEMHKELLHHPNIVHFVGFCVS-PKCL--VLEYIEGGSLDKYLHNPNY---TFS
.|| |..| .||  .|  |  .|.| |..        .    ...|..| |. | |||||.|.| |.   . |  | |||.|| |  ||....     ..
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKN-LRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPLP

PQLRLKMANDIAKGMCFLHRNEILHLDLKPQNFLVVSISPEAPVSIKLADFGLA-------TSS-------------------------SRSFYGP---T
 ..|.| | |||.|| .|| . |.| ||| .| | |..... . .||..|||.|        |.                         ... ...   |
WPQRVKIALDIACGMSYLHSMNIIHRDLKSKNCL-VRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMPMKRKIPKKCMNQRKRRMT

VEGSFLYMSPEVFTQKKFSRAADVWSYGACLIEILTNKRP
. |.   |.||. .... ....|| |.|  |.|| | ...
ICGTPYWMAPEMLLGQSYDESCDVFSFGIVLCEIITRVKA

Kinase DDB0230133.AA TyrKc 192-443 27 4.8e-42 146.91 SMART 1-280 (280) Show / Hide
Range on Protein: 192-443
Range on HMM: 1-280/280
Sequence Identity: 27% (79 aa)

LEIGNVIGGGGYGAIYKAKWRGLSVAVKVISELSDGSEFEKELEMHKEL-LHHPNIVHFVGFCV---------SPKCLVLEYIEGGSLDKYLHNPNYTFS
.. | ..| | .| .||..|. . ||||.. | .   .| .|... ..|  |||||| ..| |.          | ..|.|| ..|.|..||...  ...
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLC

PQLRLKMANDIAKGMCFLHRNEILHLDLKPQNFLVVSISPEAPVSIKLADFGLATSSSRS--------FYGP----TVE--GSFLYMSPEVFTQKKFSRA
..  |... .||.|| .||.. . | ||   | || .        .| .||||.               | .              |.||..  .||. .
MKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTK

ADVWSYGACLIEILTN-KRPYQEYDQ--LGYLELARVREEGLPPMIPPE--------IEGDLRKIIEACFHRDHTKRPNFENIEQFL
 ||||.| |. ||.|. . || .  |  .   |. .  ..|  ...||.           .. .|.. | |.|  .||.|..| ...
SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase DDB0230133.AA TK-Unique 192-443 24 3.4e-40 136.33 In-house 1-294 (294) Show / Hide
Range on Protein: 192-443
Range on HMM: 1-294/294
Sequence Identity: 24% (75 aa)

LEIGNVIGGGGYGAIYKAKWRG--------LSVAVKVISELSDGSE---FEKELEMHKELLHHPNIVHFVGFCV---SPKCLVLEYIEGGSLDKYLH---
||.|.||| | .| ..... .|         .||||   . ... .   | ||..|.|||  |||||...| |.    | ....||...|.|..||.   
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

----------------------NPNYTFSPQLRLKMANDIAKGMCFLHR--NEILHLDLKPQNFLVVSISPEAPVSIKLADFGLAT----SSSRSFYGPT
                      ..... ||.. .  | .||.|| .|..   .| | ||   | |. .        .|..|||.|.        |  .  
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTE-----DKVCKICDFGMARDVYTNGVYSMMCSQ

VEGSFLYMSPEVFT--QKKF-SRAADVWSYGACLIEILTN-KRPYQEYDQLGYLELARVREEGLPPMIPPEI-EGDLRKIIEACFHRDHTKRPNFENIEQ
 . .  .|.||..   .. . .   ||||.|  . ||.|. ..|| ....     . .  ..|  .  |..    ....... |.... ..||.|. | .
GRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKD---IMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKH

FL
 |
RL

Kinase DDB0230133.AA CZAK 192-443 35 4e-39 136.31 In-house 1-279 (279) Show / Hide
Range on Protein: 192-443
Range on HMM: 1-279/279
Sequence Identity: 35% (99 aa)

LEIGNVIGGGGYGAIYKAKWRGLSVAVKVISELSDGSEFE-KELEM-HKEL-----LHHPNIVHFVGFCVSPK----CLVLEYIEGGSLDKYLHNP-NYT
|..| .|| | .| .||| ||| .||.| |   .     | ||..|  ||      | |||.| |.| |        | | |. .||||.. |    .| 
LKFGQTIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSLRRLLTDHYFYH

FS-PQLRLKMANDIAKGMCFLHR--NE--ILHLDLKPQNFLV-VSISPEAPV-------SIKLADFGLA-TSSSRSFYGPTVEGSFLYMSPEVFTQKKFS
   | |...|| |||.|| .||    .  ||| ||  .| |   |. |  ||         | .||||        |      |.  .| ||.|    ..
KQNPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTMGCLCWMAPECFKGENYT

RAADVWSYGACLIEILTNKRPYQEYDQLGYLELARVREEGLPPM---IPPEIEGDLRKIIEACFHRDHTKRPNFENIEQFL
  .|| |.|  | .|.|   |||.   .    || . |.  |||   ..|  . .| ..|| |       || |  | |.|
EKVDVYSFGMILWCIITCDQPYQNMQPMKMAHLAAY-ENYRPPMPQPMDPMWK-NLGELIEMCWNKNPDERPSFKQILQHL

Kinase DDB0230133.AA LISK 429-443 46 0.006036 5.18 In-house 282-296 (296) Show / Hide
Range on Protein: 429-443
Range on HMM: 282-296/296
Sequence Identity: 46% (7 aa)

DHTKRPNFENIEQFL
|...||.|. |.| |
DPKNRPSFKEIVQWL