Gene GlkA (Slime mold)

GlkA

Species: Slime mold
Alias: DdisK067, GlkA, DDB0216280
External Links: DictyBase Link ,
Annotation:

Classification

Group: CMGC
Family: GSK

Sequence

Name Sequence Type Origin Length Description Download
GlkA.AA Protein None 473 None Fasta, JSON
GlkA.kin_dom Protein Kinase Domain None 275 None Fasta, JSON

Protein domain

Protein domains of GlkA.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase GlkA.AA GSK 91-366 39 2.7e-172 531.05 In-house 1-328 (328) Show / Hide 
Range on Protein: 91-366
Range on HMM: 1-328/328
Sequence Identity: 39% (130 aa)

YEIIKQVGQGTFGKVYEAKNQ----DNKRV-----AIKKVEKSNHFI-SREYDILKIV---AHPNCLRI---LDMFYTAEDN-KKMQN-LVFDFIPYTLA
||..|..|.|.||.||.|...    ..|..     ||||| .....  .||..|.|..    |||. |.    .|.|. .|. ....| ||....|.||.
YEEMKVIGHGSFGVVYQAYMNSPSNETKEIWLGPVAIKKVWQDKRYKCNRELQIMKMLGKLDHPNIVRLKYFFYMHYEKKDENHVYCNCLVMEYMPQTLY

SLLK-----KRQLSINFIKVLFYQLCQAIKHIHSKAICHRDITPNNILLS-SKGELTLADFGSAKILES--NHTSMSYICSRYYRAPELLVGCSNYTTKI
....     |.|..|..||...||........||..|||||| |.|||.  ..|.| ..||||||.||.  |....|||||||||||||. ||.|||..|
QVIRHYVKNKQQMPIIHIKLYMYQMFRGLAYLHSHGICHRDIKPQNILVDPDTGVLKICDFGSAKQLEPNKNEPNISYICSRYYRAPELIFGCTNYTCQI

DIWSIGCILAEMLIGKPLFPGTNSNDQLGRIIEVLGSPTKDDMEAMKPSKPYHLQL--------PNINPK-------------------FFESLHNVEDK
|.||.||..||||.|.||||| .|.||| .||..||.|||.....|.||.|.. .         |. ..|                   .|...|. .. 
DVWSCGCVMAEMLKGQPLFPGDSSVDQLVEIIKMLGTPTKEQIQSMNPSYPEFKFPYWSFQQIKPHPWQKNDTKYEYQTYYHKKYRTVYMFKWCHTDMQ-

TVVDLLSKIFIFDPVKRASIDEIIAHPFL
...||.||....|| || | .|..|||| 
DWIDLISKCLVYDPKKRLSPLEACAHPFF
Kinase GlkA.AA CMGC 91-366 21 8.60000000001e-116 382.19 In-house 1-513 (513) Show / Hide 
Range on Protein: 91-366
Range on HMM: 1-513/513
Sequence Identity: 21% (109 aa)

YEIIKQVGQGTFGKVYEAKN---------------QDNKRVAIKKVEKSNHFIS---------------REYDILKIVA-----------------HPNC
|||||..|.||.|.||....               ..|..|||||. .  . .                ||  ||| .                  |.|.
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

LRILDMFYTAEDNKK-------------MQNLVFDFIPYTLASLLKKRQ-----------------------------LSINFIKVLFYQLCQAIK--HI
....|.||. .....               .|||......|. ..|. |                             ..|  |.  .||.....|  ..
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLKYC

HSKA--ICHRDITPNNILLSSKGEL--------------------TLADFGSAKILESN----------------------HTSMSYICSRYYRAPELLV
||.   |.|||. | |||.....||                     ..|||.|......                      ..  .|...|.|||||.|.
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

GCSNYT---------TKIDIWSIGCILAEMLIG--------KPLFPGTNS-----------NDQLGRIIEVLGSPT---------------KDDMEAMKP
|...||         |.||.||.|||.|||. |        |||||| ..            ||| .|..|||.||               ....  |..
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

SKPYHL--------------------------QLPNINPKFFESLHNV-----------------------------------EDKTVVDLLSKIFIFDP
   |..                          ..|...|| ...|.                                     .|.  .|||.|....||
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

VKRASIDEIIAHPFL
 || ..... .||..
DKRITAEQALQHPYF
Kinase GlkA.AA S_TKc 91-366 27 3.9e-88 300.04 SMART 1-231 (231) Show / Hide 
Range on Protein: 91-366
Range on HMM: 1-231/231
Sequence Identity: 27% (82 aa)

YEIIKQVGQGTFGKVYEAKNQD-NKRVAIKKVEKSNHFISREYDILKIVAHPNCLRILDMFYTAEDNKKMQNLVFDFIPY---TLASLLKKRQ-------
|||....|.|.||||| ... . ...||||..      | || .|||   |||  ...|.|..     .   .|.....    .| ...|||.       
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---EHIRREIQILKK-HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LSINFIKVLFYQLCQAIKHIHSKAICHRDITPNNILLSSKGELTLADFGSAKILESNHTSMSYICSRYYRAPELLVGCSNYTT-KIDIWSIGCILAEMLI
..   .. ..||.|.|....||. |.|||. | ||||..  .. ..|||.|..|      .... ...|.|||.|     |.. |.|.||.||||.||| 
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLC

GKPLFPGTNSNDQLGRIIEVLGSPTKDDMEAMKPSKPYHLQLPNINPKFFESLHNVEDKTVVDLLSKIFIFDPVKRASIDEIIA-------HPFL
|.|.||      |. ......|                                   .. . |...|.. .|| || .. |. .       ||..
GYPPFP------QMQMMFKKIG-----------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase GlkA.AA CDK 91-366 29 5.5e-88 281.57 In-house 1-284 (284) Show / Hide 
Range on Protein: 91-366
Range on HMM: 1-284/284
Sequence Identity: 29% (94 aa)

YEIIKQVGQGTFGKVYEAKNQD------NKRVAIKKVEKSN-----H--FIS----REYDILKIVAHPNCLRILDMFYTAEDN-------KKMQNLVFDF
||.....|.||.|.|| |....      .. ||.||.   |     .   ..    ||  .||   |||  ...| ..| ..        ..   .||..
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

IPYTLASLLKKRQLSINFIKVLFYQLCQAIKHIHSKAICHRDITPNNILLSSKGE-----LTLADFGSAKILES------NHTSMS-YICSRYYRAPELL
... |.....        || ...|| ... ..||. | |||. |.|||....||     | .|||| |..  .      .   ..  .  . |||||||
MDHDLKKYMD--------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPELL

VGCSNYT--TKIDIWSIGCILAEMLI---GKPLFPGTNSNDQLGRIIEVLGSPTKDDMEAMKPSKPYHLQLPNINPKFFESLHNVEDKTVVDLLSKIFIF
 |...|.  | ||.||.|||.|||.    .||||||..  ||| .|....|.|| |.   .. . |..                       |||.| . .
LGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVT-KLPDY-----------------------DLLNKMLCY

DPVKRASIDEIIAHPFL
|| || | ..   ||..
DPKKRISAEQALQHPYF
Kinase GlkA.AA MAPK 91-366 30 6.6e-86 291.71 In-house 1-328 (328) Show / Hide 
Range on Protein: 91-366
Range on HMM: 1-328/328
Sequence Identity: 30% (100 aa)

YEIIKQVGQGTFGKVYEAKNQD-------NKRVAIKKVEKSNHFIS------REYDILKIV-AHPNCLRILDMFYT-----AEDNKKMQN--LVFDFIPY
|.|.|..||| .| |  |. .        .|.|||||...  .         ||  .|.    |.|  ..||.|.      .... ...   .|...   
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

TLASLLKKRQ-LSINFIKVLFYQLCQA--IKHIHSKAICHRDITPNNILLSSKGELTLADFGSAKILESN---HTS-----------MS-YICSRYYRAP
 |  ..| .| ||   |. ..||.. .  .|.|||  . |||. | |||. . ..| ..||| | .....   |..           |. |.  |.||||
DLHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAP

ELLVG--CSNYTTKIDIWSIGCILAEMLI-GKPLFPGTNSNDQLGRIIEVLGSPTKDDMEAMK-PSKP--YHLQL---PNINPKFFESLHNV----EDKT
|.. .    .||...|.||.|||.||||  .||||||... ||. .|.||||.|...... .. ....  |  .|   |. ..| .|..        .  
EIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANPQ

VVDLLSKIFIFDPVKRASIDEIIAHPFL
 .|||.|   ||| || ...| ..||..
AIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase GlkA.AA Pkinase 91-366 26 5.1e-78 270.31 Pfam 1-293 (293) Show / Hide 
Range on Protein: 91-366
Range on HMM: 1-293/293
Sequence Identity: 26% (81 aa)

YEIIKQVGQGTFGKVYEAKNQDNKR-VAIKKVEKSNHFISR--------EYDILKIVAHPNCLRILDMFYTAEDNKKMQNLVFDFIPY-----TLASLLK
|.|....|.|.||.||....... . ||.|...|..   .         |  |.| . ||| .|..|.|..   ....  .|... .       |.....
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED---KDHIY-MVMEYCEGGLYVMDLFDYIS

---KRQL--SINFIKVLFYQLCQAIKHIHSKAICHRDITPNNILLSSKGEL----TLADFGSAKI--LESNHTSMSYICSRYYRAPELLVGCSNYTTKID
   .. .  | . .|  .||........||. |.|||. | |||....|..     ..|||.||   . .|.  ... ....|.|||.. |.. |..|.|
TWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

IWSIGCILAEMLIGKPLFPGT----NSNDQLGRIIEVLGSPTKDDMEAMKPSKPYHLQLPNINPKFFESLHNVEDKTVVDLLSKIFIFDPVKRASIDEII
.||.||||.||| |.|.|||     | .||. .| ...| |.. | .   .  ...   .   .. .. .    ...  |...... .|| || ....| 
MWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-HF-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQIL

AHPFL
 ||..
QHPWF
Kinase GlkA.AA CDC2 91-366 31 1.9e-75 231.24 In-house 1-301 (301) Show / Hide 
Range on Protein: 91-366
Range on HMM: 1-301/301
Sequence Identity: 31% (95 aa)

YEIIKQVGQGTFGKVYEAKN-QDNKRVAIKKVEKSNHFIS--------REYDILKIVA-HPNCLRILDMFYTAEDNKKMQNLVFDFIPYTLASLLK----
|. |. .| ||.|.|| .|. |.|. ||.||.   .            ||  .||    |||  .. | ..     .| . .||... . |  ...    
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ----NKLY-MVFEYLDMDLKKYMDMSIP

K-RQLSINFIKVLFYQLCQAIKHIHSKAICHRDITPNNILLSSKGELTLADFGSAKILESNHTSMS---YICSRYYRAPELLVGCSNYTTKIDIWSIGCI
|  ... ...| ..||..|.. . |.. | |||. | |||...||.. .|||| |.    ..        .  . |||||.| ||. |.| .|.||||||
KNKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCI

LAEM---LIGKPLFPGTNSNDQLGRIIEVLGSPTKDDMEAMKPSKPYHLQLPNINPKFFESLHNV---------EDKTVVDLLSKIFIFDPVKRASIDEI
.|||      ||||.|    ||| .| ..||.|. .. . ..  . |    |. .|. ....             |.. .|||... . || || |..|.
FAEMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEA

IAHPFL
..||..
LQHPYF
Kinase GlkA.AA CAMK 96-366 17 3e-61 195.79 In-house 1-425 (425) Show / Hide 
Range on Protein: 96-366
Range on HMM: 1-425/425
Sequence Identity: 17% (75 aa)

QVGQGTFGKVYEAKNQ-DN------------KRVAIKKVEKS--------------------------------NHFISREYDILKIVA-------HPNC
. |.|.||||.....  ..            ..|||| ..|.                                 ... ||..|.| .        ||| 
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LRILDMFYTAED--------NKKM--------QNLVF---DFIPYT------LASLLKKRQ---------------LSINFIKVLFYQLCQAIKHIHSKA
....... ...         . ..          .|.   ....        .  . ....               ..    . .| |.|.|....||. 
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

ICHRDITPNNILLSSK-----------------GELTLADFGSAKILES------------------------NHTSMSYICSRYYRA-PELLVG-----
|.|||. | ||||...                 . . ..||| |.....                        ..    .  . .| | ||.| |     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------CSNYTTKIDIWSIGCILAEMLIGKPLFPGTNSNDQLGRIIEVLGSP-------TKDDMEAMKPS-KPYHLQLPNINPKFFESLHNVEDK---
           |. |.|.||.|.||  || |.| | | . |.... . |    .       ..    . | .  |...  . .| .  |  ... |    
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICE-D-E----WIGMNDYELFEKIMKGKYDFPPPYFSPISCN-YGPEWWDDISDEFHH

----TVVDLLSKIFIFDPVKRASIDEIIAHPFL
     . ||..|.   || ||..|... .||..
FVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase GlkA.AA ERK7 91-366 32 1.3e-60 205.96 In-house 1-292 (292) Show / Hide 
Range on Protein: 91-366
Range on HMM: 1-292/292
Sequence Identity: 32% (97 aa)

YEIIKQVGQGTFGKVYEAKNQDNKR-VAIKKV------EKSNHFISREYDILKIVA-HPNCLRILDMFYTAEDNKKMQNLVFDFIPYTLASLLK-KRQLS
|||.|..|.| .| |  |  .  |  ||.||.      .       ||  .|.    ||| .|.....  |. .. .  |||.|    |    .  . | 
YEIRKRLGKGAYGIVWKAYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVI-RADNDRDIY-LVFEFMETDLHAVIRKGNILK

INFIKVLFYQLCQAIKHIHSKAICHRDITPNNILLSSKGELTLADFGSAKILESNH-------TSMSYICSRYYRAPELLVGCSNYTTKIDIWSIGCILA
    .. .||| .|||..||  . |||. | |||| |.  . ..||| |  . .             |.  | ||||| |.|  .||  .| |||||||.
DIHKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECMVKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGCILG

EMLIGKPLFPGTNSNDQLGRIIEVLGSPTKDDMEAMKPSKPYHL--QLPNINPKFFESLHNVEDKTVVDLLSKIFIFDPVKRASIDEIIAHPFL
|||.|||.||||   .|. .|.|... ||. |.||....    .  |..  ..| .. .     .  .||| .. .| | || .... ..||. 
EMLRGKPMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMNQQKRKTLDQMMPQCCDDAIDLLKRLLVFNPKKRLTAEQALQHPYV
Kinase GlkA.AA p38 91-366 33 1.9e-59 201.77 In-house 1-289 (289) Show / Hide 
Range on Protein: 91-366
Range on HMM: 1-289/289
Sequence Identity: 33% (98 aa)

YEIIKQVGQGTFGKVYEA--KNQDNK--RVAIKKVEK---SNHF---ISREYDILKIVAHPNCLRILDMFYT-AEDNKKMQN--LVFDFIPYTLASLLKK
|. .. ||.| .|.|  |  .  ..|  .|||||  .   | ..   . ||   ||   | | . .|| |   |.. . .|.  .|  |    |  ..| 
YQNLQPVGSGAYGQVCKAEDRRTGQKRRYVAIKKLMRPFQSEIHAKRTYRELRLLKHMRHENVICLLDVFTPPAHSMNDFQDVYMVTHFMGADLNNIMKC

RQLSINFIKVLFYQLCQAIKHIHSKAICHRDITPNNILLSSKGELTLADFGSAKILESNHTSMSYICSRYYRAPELLVGCSNYTTKIDIWSIGCILAEML
 .||   |. | ||.  . | |||  | |||  | || .    ||   ||| |   ..  |   |.  | ||||| .     || ..||||.|||.||..
QRLSDDHIQFLVYQILRGLKYIHSAGIIHRDLKPSNIAVNEDCELRILDFGLARHCDDEMT--GYVATRWYRAPEIMLNWMHYTQTVDIWSVGCIMAELI

IGKPLFPGTNSNDQLGRIIEVLGSPTKDDME--AMKPSKPYHLQLPNINPKFFESLHNVEDKTVVDLLSKIFIFDPVKRASIDEIIAHPFL
 |..||||.. .||| ||..|.|.|..  ..  ... .. |   .| .  . |...    .   .||| |. . || || .  | ..||..
TGRTLFPGDDHIDQLQRIMKVCGTPDEEFWQKIQSEEARNYIQSYPQMPRRDFHHVFMGANPQAIDLLEKMLELDPDKRITAEEAMQHPYF
Kinase GlkA.AA ERK 179-366 36 6.2e-54 185.5 In-house 104-307 (307) Show / Hide 
Range on Protein: 179-366
Range on HMM: 104-307/307
Sequence Identity: 36% (75 aa)

QLSINFIKVLFYQLCQAIKHIHSKAICHRDITPNNILLSSKGELTLADFGSAKILES----NHTS----MS-YICSRYYRAPELLVGCSNYTTKIDIWSI
.||  ... . ||.  ..|.|||  . |||. | |||. | . |  .||| | ....    ||..    |. |. .|.|||||..   ..||...||||.
ELSDDHCQYFMYQILCGLKYIHSANVIHRDLKPSNILVNSNCDLKICDFGLARCFDASYQENHECNQNFMTEYVATRWYRAPEIMLSWQKYTKAMDIWSC

GCILAEMLIGKPLFPGTNSNDQLGRIIEVLGSP-TKDDMEAM--KPSKPYHLQLPN--INPKFFESLHNVED--KTVVDLLSKIFIFDPVKRASIDEIIA
|||.|||| .|||||| .. .|. ||....|.| ...|..    .  . |  .|||  . || .|..    .  .  .|||.|   ||| || ...| ..
GCIFAEMLGRKPLFPGKDYVHQINRIFQIIGTPHSEEDLQYICSENAWKYIKNLPNPVRPPKPWENIFPNANCNPQAIDLLEKMLVFDPDKRITVEECLE

HPFL
||..
HPYF
Kinase GlkA.AA MAPK-Unclassified 242-366 26 5.9e-31 108.91 In-house 408-575 (575) Show / Hide 
Range on Protein: 242-366
Range on HMM: 408-575/575
Sequence Identity: 26% (44 aa)

YICSRYYRAPELLVGCSNYTTKIDIWSIGCILAEMLIG-----------KPLFPGTN--------------------SNDQLGRIIEVLGSPTKDDMEAM
|.  |.|||||..   ..|.|..||||||||.|||..            .|||||..                    . ||.  |...||.| . |.   
YVVTRWYRAPEIMLSMHEYDTQVDIWSIGCIFAEMMQMYDRHNPTFSDHRPLFPGQDCFPITPDRNNDVDQGGFPHSHQDQIKMIFDYLGMPPEEDCNFI

KPSKPYHL--QLPNINPKFFESLHNVEDK----------TVVDLLSKIFIFDPVKRASIDEIIAHPFL
. ..   .   .   .|  | .| . .               |...| . |.| || ..|..  ||. 
TCDSARKYIQSFKCKTPVHFTDLMFCKAPGDDQIVRGNCECIDFVQKMLQFNPWKRITADQALEHPYF
Kinase GlkA.AA MAPK-Unclassified 91-236 31 1.5e-27 96.35 In-house 1-162 (575) Show / Hide 
Range on Protein: 91-236
Range on HMM: 1-162/575
Sequence Identity: 31% (51 aa)

YEIIKQVGQGTFGKVYEAK-NQD-NKRVAIKKVE-KSNHFIS-----REYDILKIVAHPNCLRILDMFYTAEDNK---KMQNLVFDFIPY---TLASLLK
|| .| .|.| .| |..|. ..  |. ||||||  ..   .      ||  || .  ||| ..| |.||. |.     .   .| |. .     | ...|
YEYQKNIGSGAYGQVCRAMDKKNQNQQVAIKKVNHIFHNHTDCKRVLREIRILRYLNHPNIIQIQDIFYNKELHNQEFDDIYIVMDYMQTSLFDLHQIIK

KRQ--LSINFIKVLFYQLCQAIKHIHSKAICHRDITPNNILLSSKGELTLADFGSAKILESN
 .|  ..   |. .|||.   .| .||  | |||  | |.|.  .. .  .||| ..  | |
SNQDHWCHQHIQYFFYQILRGLKYLHSACIIHRDLKPSNLLINQDCSVRICDFGMSRSIEDN
Kinase GlkA.AA TyrKc 91-366 19 3.6e-11 -41.99 SMART 1-280 (280) Show / Hide 
Range on Protein: 91-366
Range on HMM: 1-280/280
Sequence Identity: 19% (60 aa)

YEIIKQVGQGTFGKVYEAKNQDNKRVAIKKVEKSNHFIS---REYDILKIV--AHPNCLRILDMFYTAEDNK------KMQNLVFDFIPY-TLASLLKKR
 . .|. | | ||.||...      ||.|.. ..   .    ||  |.. .   ||| .|..     . . .      .   .|. . |.  | . |.|.
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLY---GVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

Q--LSINFIKVLFYQLCQAIKHIHSKAICHRDITPNNILLSSKGELTLADFGSAKILESN--------HTSMSY-ICSR-----YYRAPELLVGCSN-YT
.  |.        .| ..   ..||| . |||.   |.|.....    .||| .. ...           ...   ...        ||| .    . .|
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--NYGKFT

TKIDIWSIGCILAEML-IGKPLFPGT----NSNDQLGRIIEVLGSPTKDDM--EAMKPSKPYHLQLPNINPKFFESLHNVE-DKTVVDLLSKIFIFDPVK
|| |.|| |  . |..  |..  ||      ||... . ..  . . . .   . |                 |     |.  . . .. ..   .|| .
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYP-MS----------------F-----VCCPDEMYQIMKQCWHEDPED

RASIDEIIAHPFL
| .  ||  | ..
RPTFSEI--HECF
Kinase GlkA.AA ERK 91-123 41 3.4e-09 30.57 In-house 1-39 (307) Show / Hide 
Range on Protein: 91-123
Range on HMM: 1-39/307
Sequence Identity: 41% (16 aa)

YEIIKQVGQGTFGKVYEAKNQD------NKRVAIKKVEK
|.||||.|.|..| |  |...       ...|||||.|.
YQIIKQIGHGAYGVVCSAIDKEYCFDETGQKVAIKKIEN
Kinase GlkA.AA Pkinase_Tyr 91-142 25 2.8e-05 18.49 Pfam 1-65 (270) Show / Hide 
Range on Protein: 91-142
Range on HMM: 1-65/270
Sequence Identity: 25% (17 aa)

YEIIKQVGQGTFGKVYEAKNQ-----DNKRVAIKKV--EKSNH------FISREYDILKIV-AHPN
 ...|. |.| ||.||...       ..  ||.|..    . .      |.. |  |.|    |||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPN
Kinase GlkA.AA Pkinase_Tyr 190-268 25 0.335541 4.69 Pfam 118-199 (270) Show / Hide 
Range on Protein: 190-268
Range on HMM: 118-199/270
Sequence Identity: 25% (21 aa)

YQLCQAIKHIHSKAICHRDITPNNILLSSKGELTLADFGSAKIL----ES-NHTSMSYICSRYYRAPELLVGCSNYTTKIDIWS
.| ...  . .|| . |||.   |.|.....    .||| |. .    .    .. . .  . . ||| .  .  .||| |.||
WQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWM-APECINYGK-FTTKSDVWS