Gene pk2 (Slime mold)

pk2

Species: Slime mold
Alias: pk2, pkfA, DK2, DDB0191365, PKBR1, pkgB, DdisK021
External Links: DictyBase Link ,
Annotation:

Classification

Group: AGC
Family: SGK

Sequence

Name Sequence Type Origin Length Description Download
pk2.AA Protein None 479 None Fasta, JSON
pk2.kin_dom Protein Kinase Domain None 255 None Fasta, JSON

Protein domain

Protein domains of pk2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase pk2.AA SGK 153-407 56 2.8e-216 675.08 In-house 1-283 (283) Show / Hide 
Range on Protein: 153-407
Range on HMM: 1-283/283
Sequence Identity: 56% (159 aa)

FELLNVIGKGSFGKVMQVKKKGE------------------DKIFAMKVLRKDAII-------ARKQVNHTKSEK-TILQCISHPFIVNLHYAFQTKDKL
|..|.||||||||||.|||.|..                  ||..|||||.|..||       ..|...|...|. .||....||||||||||||||.||
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YMVLDFVNGGELFFHLKREGRFSEPRVKIYAAEIVSALDHLHKQDIVYRDLKPENILLDSEGHICITDFGLSK-KIETTDGTFTFCGTPEYLAPEVLNGH
|.|.|.|||||.|.||.||..|.|.|...||||||.||..||.|||.||||||||||||..||.|.|||||.| .|.|.|.||||||||||||||||...
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

GHGCAVDWWSLGTLLYEMLTGLPPFYSQNVSTMYQKILNGELKIPTYISPEAKSLLEGLLTREVDKRLGTK-GGGEVKQHPWF
.|...||||.||..||||..|||||||.|...||..|.|..|.||...|..|..|..|||.....|||||| ...|.|.||.|
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase pk2.AA AGC 153-407 38 8e-205 535.94 In-house 1-395 (395) Show / Hide 
Range on Protein: 153-407
Range on HMM: 1-395/395
Sequence Identity: 38% (152 aa)

FELLNVIGKGSFGKVMQVKKK------GEDKIFAMKVLRKDA-IIARK--QVNHTKSE------------KTILQCIS----------HPFIVN-LHYAF
||.| ||||||||||..|.||      . .|..|||||.|.  |. .|  .| ||..|            . ||. ..          |||||. |||.|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTKDK--LYMVLD----FVN-----GG-ELFFHLK---REGRFSEPRVKIYAAE-------IVSALDHLHK-QDIVYRD-LKPENILLDSEGHICITDFG
|.||.  ||.|..    .||     || |||.||.   .||||.|.|...||||       ||.||..||. ..|..|| |||||||||..|||..||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSKKIET---------------------------------------------------TDGTFTFCG--TPEYLAPEVLNGHGHGCAVDWWS--LGTLLY
|.|.. .                                                   .| | ||||  ||||.|||.|    .| |.||||  || |.|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMLTGLPPFYSQNVS----------TMYQKIL------NGELKIP----------TYISPEAKSLLEGLLTREVDKRLGTKGGG-------EVKQHPWF
|||||.||||..|.            |.|||.      | ..|.|           ..|||||.|...||... .||||..|..       |.|.||||
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase pk2.AA Akt 153-407 59 2.8e-188 607.08 In-house 1-264 (264) Show / Hide 
Range on Protein: 153-407
Range on HMM: 1-264/264
Sequence Identity: 59% (156 aa)

FELLNVIGKGSFGKVMQVKKKGEDKIF-AMKVLRKDAIIARKQVNHTKSEKTILQCISHPFIVNLHYAFQTKDKLYMVLDFVNGGELFFHLKREGRFSEP
|..|.|.||||||||..||||  .|.. |||||.|| ||...|| ||| |. ||| . |||||||||.|||.||||.|.|..||||||.||.|..||||.
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

RVKIYAAEIVSALDHLHKQDIVYRD-LKPENILLDSEGHICITDFGLSKKI-ETT-DGTFTFCGTPEYLAPEVLNGHGHGCAVDWWS-LGTLLYEMLTGL
| . |.|||..|..|||...|.||| |||||||.|..||||.|||||.|..  .  | | ||||||||||||.|||.||. |||||. || ..|||..|.
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

PPFYSQNVSTMYQKILNGELKIP--TYISPEAKSLLEGLLTREVDKRLG--TKGGGEVKQHPWF
||||.|.. .|..||.|...|.|   .||||.|.|..|||..  .||||   ..  |.|.||||
PPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase pk2.AA PKA 153-407 49 2.6e-146 492.39 In-house 1-263 (263) Show / Hide 
Range on Protein: 153-407
Range on HMM: 1-263/263
Sequence Identity: 49% (131 aa)

FELLNVIGKGSFGKVMQVKKKGEDKIFAMKVLRKDAIIARKQVNHTKSEKTILQCISHPFIVN-LHYAFQTKDKLYMVLDFVNGGELFFHLKREGRFSEP
||.....|.||||.||....|.  ...|||.|.|. |. .||| |...||.||| |.|||||. . . ||. ..||||...|.|||.| .| ..||||.|
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

RVKIYAA-EIVSALDHLHKQDIVYRDLKPENILLDSEGHICITDFGLSKKIETTDGTFTFCGTPEYLAPEVLNGH-GHGCAVDWWSLGTLLYEMLTGLPP
  |.||| .||.||. ||.|.|.||||||||||.|..||| ||||| .||...   |.| ||||||||||..... ||| .||||.|| | ||||.| ||
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD--RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPP

FYSQ--NVSTMYQKILNGELKIPTYISPEA---KSLLEGLLTREVDKRLGTKGG--GEVKQHPWF
||    ..  .|.||.||..| | .... |   |.|.. ||.. . ||.|.. .    .| |.||
FYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase pk2.AA AktR 153-407 48 7.6e-146 490.82 In-house 1-268 (268) Show / Hide 
Range on Protein: 153-407
Range on HMM: 1-268/268
Sequence Identity: 48% (129 aa)

FELLNVIGKGSFGKVMQVKKK-GEDKIFAMKVLRKDAIIARKQVNHTKSEKTILQ-CISHPFIVNLHYAFQTKDKLYMVLDFVNGGELFFHLKREGRFSE
|......||| ||||. |.||  ..|..|||...|  || |.|  ||  |..|.. |..|||||.|||.||||.||. ..... |||||.|||....|||
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

PRVKIYAAEIVSALDHLHKQ-DIVYRDLKPENILLDSEGHICITDFGLSK---KIETTDGTFTFCGTPEYLAPEVLNG-HGHGCAVDWWSLGTLLYEMLT
 ....|.|.|. ||..||.. .|.||||||||||||..||..||||||||   ... .. . .|||||||.|||...   ||. .||||..|...|||.|
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GLPPFYSQNVSTMYQKILNGE-LKIPTY--ISPEAKSLLE-GLLTREVDKRLG--TKGGGEVKQHPWF
|.||||..|  .|.|||.. . .|.|..  .|...|.|.. .|| .   ||||  ..|  |.| ||||
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase pk2.AA RSK 156-407 47 3.3e-136 458.8 In-house 1-278 (278) Show / Hide 
Range on Protein: 156-407
Range on HMM: 1-278/278
Sequence Identity: 47% (132 aa)

LNVIGKGSFGKVMQVKKK---GEDKIFAMKVLRKDAIIARKQ-VNHTKSEKTILQCIS-HPFIVNLHYAFQTKDKLYMVLDFVNGGELFFHLKREGR---
| | |.|..||| ...|.     ..|.|||||.|  |..|.  . ||. | .||. .  |||||.|||||||..|||.......||||| ||..|..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FSEPRVKIYAAEIVSALDHLHKQDIVYRDLKPENILLDS---EGHICITDFGLSKK--IETTDGTFTFCGTPEYLAPEVLN----GHGHGCAVDWWSLGT
||| ....|.||||.|..|||.|.|..|||||||||.|.   |||| .||||..|.  .. .  | |||.| ||.|||.|.    . ||. |.|||||| 
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LLYEMLTGLPPFYS---QNVSTMYQKILNGE--LKIP--TYISPEAKSLLEGLLTREVDKRLG--TKGGGEVKQHPWF
|.|||||| |||..   .| .   ..|..|.  |..|   |.|.|||.|. ..|.|.  ||||   ..  |.||||||
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase pk2.AA p70 153-407 44 1.9e-125 423.03 In-house 1-299 (299) Show / Hide 
Range on Protein: 153-407
Range on HMM: 1-299/299
Sequence Identity: 44% (132 aa)

FELLNVIGKGSFGKVMQVKKKG---EDKIFAMKVLRKDAI-IARKQVNHTK-------------------------SEKTILQCISHPFIVNLHYAFQTK
|||| |.||| .|||.||.|     . ||.|||||||  | .  |   ||.                          |  ||  . ||||. ||||||| 
FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNILEEVKHPFICDLHYAFQTN

DKLYMVLDFVNGGELFFHLKREGRFSEPRVKIYAAEIVSALDHLHKQDIVYRDLKPENILLDSEGHICITDFGLSKK-IETTDG----------TFTFCG
 ||| .|..  ||||| ||.|.| . |  .. |..||. || |||...|.||||||||..|.. ||.  |||||.|. |.              |.||||
GKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFCG

TPEYLAPEVLNGHGHGCAVDWWSLGTLLYEMLTGLPPFYSQNVSTMYQKILNGE--LKIPTYISPEAKSLLEGLLTREVDKRLG--TKGGGEVKQHPWF
|.|| |||.| . ||. |||||||| |.| |||| |||   |      ||| |   ||.| | ..|.. |.  || |....|.|      .....||.|
TIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF
Kinase pk2.AA RSK-Unclassified 153-407 41 2.1e-124 392.89 In-house 1-283 (283) Show / Hide 
Range on Protein: 153-407
Range on HMM: 1-283/283
Sequence Identity: 41% (117 aa)

FELLNVIGKGSFGKVMQVKKKGEDKIFAMKVLRKDAIIARKQVNHTKSEKTILQCISHPFIVNLHYAFQTKDKLYMVLDFVNGGELFFHLK--REGRFSE
|.    ||.|.||||  |.||. ..|.||||| |. .| .. .     |. |.    ||||| | ..|||.|.||.....  ||..| ||   .| .|.|
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE

PRVKIYAAEIVSALDHLHKQDIVYRDLKPENILLDSEGHICITDFGLSKKI----------------------ETTDGTFTFCGTPEYLAPEVLNGHGHG
 .|..||.|.. || .|||.|..||||||.||.|. |||.  |||.||..                       .   .|  |||| ||||||.. . ||.
DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCGHT

CAVDWWSLGTLLYEMLTGLPPFYSQNVSTMYQKILNGELKIP--TYISPEAKSLLEGLLTREVDKRLGTKGG--GEVKQHPWF
 ||||| || ..|||| |.||.|  |   ... |. ...|.|   ||| ....|.  ||.|   |||| | |   ..|.|| |
KAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF
Kinase pk2.AA RSK 153-407 44 3.7e-123 415.44 In-house 1-271 (271) Show / Hide 
Range on Protein: 153-407
Range on HMM: 1-271/271
Sequence Identity: 44% (122 aa)

FELLNVIGKGSFGKVMQVKKK---GEDKIFAMKVLRKDAIIARKQVNHTKSEKTILQCISHPFIVNLHYAFQTKDKLYMVLDFVNGGELFFHLKREGRFS
.||. .||.|||.||  .||.     .. .|||...|... .. .   .. |  ||  . ||||| |||.||.  |.||..||  ||.|| .| ... ||
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR-VCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMFS

EPRVKIYAAEIVSALDHLHKQDIVYRDLKPENILLDSE----GHICITDFGLSKKIETTDG-TFTFCGTPEYLAPEVLNGHGHGCAVDWWSLGTLLYEML
|  ||.|.||| .|...||.|.||.|||||||||.|.|    ||| |.|||..|.    .| . |||.| .|.|||||.  ||. |.||||.|.|.||||
EREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEML

TGLPPFYSQNVSTMYQKILNGELKI-------PTYISPEAKSLLEGLLTREVDKRLGT--KGGGEVKQHPWF
|| .||....  |. ..|..  | .       . .||.|||.|| ..|.|   .|||.   |  ..||||||
TGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF
Kinase pk2.AA PKC 153-407 45 5.70000000001e-121 393.9 In-house 1-262 (262) Show / Hide 
Range on Protein: 153-407
Range on HMM: 1-262/262
Sequence Identity: 45% (120 aa)

FELLNVIGKGSFGKVMQVKKKGEDKIFAMKVLRKDAIIARKQVNHTKSEKTILQCIS-HPFIVNLHYAFQTKDKLYMVLDFVNGGELFFHLKREGRFSEP
|..| |.||||||||| ...|| |...|.|||.||.||    |  |  || .|   . ||| ..||  |||.|.|. |. .|||| | ||  . .||.|.
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

RVKIYAAEIVSALDHLHKQDIVYRDLKPENILLDSEGHICITDFGLSKK-IETTDGTFTFCGTPEYLAPEVLNGHGHGCAVDWWSLGTLLYEMLTGLPPF
. . |||||..||  ||...|.||||| .|.|||.|||| |.|||..|  .   | | ||||||.|.|||.| .   | .||||..| |.|||. | .||
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF

YSQNVSTMYQKILNGELKIPTYISPEAKSLLEGLLTREVDKRLGT-----KGGGEVKQHPWF
  ..  .. | |.. .  .| ..| ||.|...|..|..  ||||      .| .....|| |
HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase pk2.AA S_TKc 153-407 39 2.6e-117 396.94 SMART 1-231 (231) Show / Hide 
Range on Protein: 153-407
Range on HMM: 1-231/231
Sequence Identity: 39% (107 aa)

FELLNVIGKGSFGKVMQVKKKGEDKIFAMKVLRKDAIIARKQVNHTKSEKTILQCISHPFIVNLHYAFQTKDKLYMVLDFVNG--GELFFHLKREGR---
.|.|..||||.||||.....|. ..|.|.|...          .|...|  ||.   ||.||.|...||. |.||||.....|  |.|| ..|. ||   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FSEPRVKIYAAEIVSALDHLHKQDIVYRDLKPENILLDSEGHICITDFGLSKKIETTDGTFTFCGTPEYLAPEVLNGHGHGC-AVDWWSLGTLLYEM
   |.| ... |...|..||...|.. |..|||||||||||.  || |.||||....       ||||||.|.|||||   |.|. ..||||.| .||||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

LTGLPPFYSQNVSTMYQKILNGELKIPTYISPEAKSLLEGLLTREVDKRLGTKGGGE----VKQHPWF
|.| |||.  .. .|..||.          |||||......|... .||..     .    .|.||||
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase pk2.AA Pkinase 153-407 34 8.70000000001e-101 345.93 Pfam 1-293 (293) Show / Hide 
Range on Protein: 153-407
Range on HMM: 1-293/293
Sequence Identity: 34% (104 aa)

FELLNVIGKGSFGKVMQVKKKGEDKIFAMKVLRKDAIIARKQVNHTK-SEKTILQCISHPFIVNLHYAFQTKDKLYMVLDFVNGG----ELFFHLK--RE
.... .||.||||.| . ..||. ||.|.|...|. .   |...|.. ||  |.. ..||.|| |...|..||..|||.....||    .|| ...  |.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GRF--SEPRVKIYAAEIVSALDHLHKQDIVYRDLKPENILLDSEGHI----CITDFGLSKK--IETTDGTFTFCGTPEYLAPEVLN-GHGHGCAVDWWSL
|.|  ||  .| |. .|...|...|.. |..|||||||||.|..|||    .|.||||.|.  .     . ||||||.|.||||.. | ..| .||.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GTLLYEMLTGLPPFYSQ------NVSTMYQKILNGELKIPTYIS---------------------PEAKSLLEGLLTREVDKRLGTKGGGEVKQHPWF
| .|||||.| |||...      .   |...|. ..|. . . .                     .|.|......|..   ||..     ...|||||
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT---AEQILQHPWF
Kinase pk2.AA S_TK_X 408-473 37 3.4e-21 77.65 SMART 1-79 (79) Show / Hide 
Range on Protein: 408-473
Range on HMM: 1-79/79
Sequence Identity: 37% (30 aa)

KNIDWEKLDR--KEVEVHFKPKVK----SGTDISQIDPVFTQERPMDSLVETSALGDAMGK-------DTSFEGFTYVA
..|||.|| .  ||.|  ||||.|    | ||.|. || || | ||.. ... ... .  .       .. |.|||||.
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase pk2.AA TyrKc 153-415 19 5.3e-15 19.87 SMART 1-280 (280) Show / Hide 
Range on Protein: 153-415
Range on HMM: 1-280/280
Sequence Identity: 19% (60 aa)

FELLNVIGKGSFGKVMQVKKKGEDKIFAMKVLRKDAIIARKQVNHTKSEKTILQCI--SHPFIVNLHYAFQTK-------DKLYMVLDFVNGGELFFHLK
 .|. ..| | ||.|.. . |      | |.|..||      .    .|  |.  .  .|| ||.|. .  ..       . |..|. .. .| |  .|.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

REGR-FSEPRVKIYAAEIVSALDHLHKQDIVYRDLKPENILLDSEGHICITDFGLSKKIETT------DGTFTF----CGTP----EYLAPEVLNGHGHG
. .. .. .    ..  | .  ..||.. .. |||   |.|....... |.|||||..|.        . . .     .|        .|||..| .   
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

CAVDWWSLGTLLYEMLT-GLPPFYS-----QNVSTMYQKILNG-ELKIPTY--------ISPEAKSLLEGLLTREVDKRLGTKGGGEVKQHPWFKNIDWE
 . | || | ...|..| | .| .       . . ..... .|  ...| .         ..|  .. .    .. ..|            | |..|  |
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDR------------PTFSEI-HE

KL
..
CF
Kinase pk2.AA Pkinase_Tyr 153-366 22 5e-14 48.14 Pfam 1-233 (270) Show / Hide 
Range on Protein: 153-366
Range on HMM: 1-233/270
Sequence Identity: 22% (53 aa)

FELLNVIGKGSFGKVMQVKKK----GEDKIFAMKVLRKDAIIA---RKQVNHTKSEKTILQCI-SHPFIVNLHYAFQ-TKDK--LYMVLDFVNGGELFFH
 ... ..|.|.||.|.. . |    ...   | |.|. .|      |.      .|  |.  . .|| ||.|. .    ..   .|.|. .. .| |  .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDF---MREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY

LKR----EGRFSEPRVKIYAAEIVSALDHLHKQDIVYRDLKPENILLDSEGHICITDFGLSKKI-------ETTDGTFTFCGTPEYLAPEVLNGHGHGCA
|..    ..... ..   ....| .....|. . .. |||   |.|....... |.||||.. |        ...|.  .      .|||..|      .
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LP--IKWMAPECINYGKFTTK

VDWWSLGTLLYEMLT-GLPP-FYSQNVSTMYQKI-LNGE
 | || | |..|..| |  | ..    . .|..|  .|.
SDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGY
Kinase pk2.AA Pkinase_C 427-475 42 6.8e-13 48.63 Pfam 1-46 (46) Show / Hide 
Range on Protein: 427-475
Range on HMM: 1-46/46
Sequence Identity: 42% (21 aa)

KVKSGTDISQIDPVFTQERPMDSLVETSALGDAMGKDTSFEGFTYVADS
.||| ||.|  || ||.|.|||.    .      |..  |.|||||...
QVKSPTDTSNFDPEFTDEPPMDTP--PDWR-MSSGDQEPFRGFTYVNPD