Gene TSSK2 (Human)

TSSK2

Species: Human
Alias: STK22B, FLJ38613, DGS-G, TSSK2, SPOGA2
External Links: iHOP , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , GeneCards
Annotation: Consensus chromosomal location: 22q11.2-q11.1,

Classification

Group: CAMK
Family: TSSK

Sequence

Name Sequence Type Origin Length Description Download
TSSK2.NA RNA Sugen Kinome 1832 None Fasta, JSON
TSSK2.AA Protein Sugen Kinome 358 None Fasta, JSON
TSSK2.kin_dom Protein Kinase Domain Sugen Kinome 261 None Fasta, JSON

Protein domain

Protein domains of TSSK2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase TSSK2.AA TSSK 12-272 55 1.7e-194 643.74 In-house 1-289 (289) Show / Hide 
Range on Protein: 12-272
Range on HMM: 1-289/289
Sequence Identity: 55% (161 aa)

YIVGINLGKGSYAKVKSAYSERLKFN----------------VAVKIIDRKKTPTDFVERFLPREMDILAT-VNHGSIIKTYEIFETSDGRIYIIMELGV
|.||...|.||||||..|||.. |..                ||.||||||| |||....|||||..|... ..| .||..||.|||..|.||..||...
YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIKIIDRKKAPTDYLNKFLPREIQIMRKTLKHPNIIQFYEMFETCQGKIYMVMEYAE

QGDLLEFIKCQ------GALHEDVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRI-ILSKTFCGSAAYAAPEVL
.|||||.|..       |||||. |||.|||..|||||||....|||||||||.||||..||||.||||.... ||..||. .||||||||.||||||.|
HGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKHWNIKLTDFGFARYWPRDDPGRCCHLSKTFCGSYAYAAPEIL

QSIPYQPKVYDIWSLGVILYIMVCGSMPYDD--SDIRKMLRIQKEHRVDFPR--SKNLTCECKDLIYRMLQPDVSQRLHIDEILSHSWL
..|||.||.||.||.||||||||||.||.||  |.|.|||..|.||.| ||.  |.....||||||..||||....|.||.||..|.|.
RGIPYDPKWYDVWSMGVILYIMVCGCMPFDDDKSNIHKMLWQQQEHKVCFPKPHSCWISQECKDLIRHMLQPHPCNRPHINEICHHCWM
Kinase TSSK2.AA CAMK 17-272 25 1.3e-116 377.39 In-house 1-425 (425) Show / Hide 
Range on Protein: 17-272
Range on HMM: 1-425/425
Sequence Identity: 25% (110 aa)

NLGKGSYAKVKSAYSERLK------------FNVAVKIIDRKKTP-------------------------TDFVERFLPREMDILAT-------VNHGSI
 ||.||..||| ..  . .              ||.||||.|| .                         ... .....||..|. .       ..|  |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKTYEIFE------------TSDG-------RIYIIM---ELGVQG----DLLEFIKCQ---------------GALHEDVARKMFRQLSSAVKYCHDLD
|| ||..|            | .        ..|..|   |.   |    ||...|. .               | ..|. ||..|||. |||.|||...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IVHRDLKCENLLLDKD-----------------FNIKLSDFGFSKRCLRDSNGRII-------------------LSKTFCGSAAYAA-PEVLQS-----
|||||||.||.|||..                 .|||..||||.... ...| . .                   . |||||. .|.| ||||..     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------IPYQPKVYDIWSLGVILYIMVCGSMPYDDS-------------DIRKMLRIQKEHRVDFPRSK----------------------NLTCECK
        .|| ..  |.||.|||||||.|| .|....             .......  .. . ||| ..                      ... |||
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DLIYRMLQPDVSQRLHIDEILSHSWL
||| .|||.| ..|. |...|.| |.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase TSSK2.AA CAMKL 12-272 38 5.3e-113 362.0 In-house 1-297 (297) Show / Hide 
Range on Protein: 12-272
Range on HMM: 1-297/297
Sequence Identity: 38% (115 aa)

YIVGINLGKGSYAKVKSAYSERL-KFNVAVKIIDRKKTP-TDFVERF-----------LPREMDILATVN---HGSIIKTYEIFETSD-----GRIYIIM
|..|  |||||..||| |  .|. .  ||.||||.||.   .....            . ||. |.  .|   |  ||| ||..||..     . ||..|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELGVQGD--LLEFIKCQGA----LHEDVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLDKDF--NIKLSDFGFSKRCLR--DSNGRIILSKTFCGSAA
|.   |.  |...|. .|     ..|. ||..|||. |||.|||...|||||.| ||.|||..   |||..|||||  . .  . .|.  . |||||| .
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQ--KLKTFCGSPP

YAAPEVLQS--IPYQPKVYDIWSLGVILYIMVCGSMPYDDS--------DIRKMLRIQKEHRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHIDEILSHS
|.|||..|.   ||  .  ||||.||||| |||| .| ||         .| .........   .|  . .  .|.||| .|||.. ..|  |..|..| 
YMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHP

WL
|.
WM
Kinase TSSK2.AA MARK 12-272 38 4.3e-96 314.59 In-house 1-262 (262) Show / Hide 
Range on Protein: 12-272
Range on HMM: 1-262/262
Sequence Identity: 38% (105 aa)

YIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVE-RFLPREMDILATVNHGSIIKTYEIFE--TSDGRIYIIMELGVQGDLLEFIKCQ--G
| ..  .|.||||||| | . . . .||.||....|  .|. . . . ||..|.  ..|  ||| ....|  |.   ||.|||.   |.|...|| .  |
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFK-LNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNG

ALHEDVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLDKDF--NIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQSIPYQPKVYDIWSLGV
 |||. ||..|||. |||.|||. .|||||.|.||.|.|..   |||..||||| ..  ..       .||||. .|.|||.... ||  .  |||||||
RLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQK-----LNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGV

ILYIMVCGSMPYDDSD--IRKM-LRIQKEHRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHIDEILSHSWL
.||.||||. |.|...  . ..  .|....   ...   .  ||..|| |.|... ..|  |.||..|.|.
VLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCH---VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase TSSK2.AA S_TKc 12-272 31 2e-92 314.27 SMART 1-231 (231) Show / Hide 
Range on Protein: 12-272
Range on HMM: 1-231/231
Sequence Identity: 31% (88 aa)

YIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQ--GDLLEFIKCQGA--
| ..  .|||...||. ..  . .  ||.|||.          . . ||..||   .|  |.| |..|..  ...|..||.  .  |||...|| .|   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LHEDVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQSIPYQPKVYDIWSLG
    ..| .||....|. .|..|||.. |.||||| ||.|||.  .||..|||....            .||||.  | |||||   .| ..  |.||.|
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCG

VILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHIDEILS-------HSWL
.|||.|.||  |..  .. .|... .            . |.||.| ..|| | ..|. . |.|        | |.
CILYEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase TSSK2.AA AMPK 12-272 40 4.3e-87 258.6 In-house 1-254 (254) Show / Hide 
Range on Protein: 12-272
Range on HMM: 1-254/254
Sequence Identity: 40% (107 aa)

YIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHGSIIKTYEIF-ETSDGRIYIIMELGVQGDLLEFIKCQGALHE
||.| ..|.|.. ||| .. .. .  ||.||....|   . .   . || .||  ..| .||. ||.  || .  |...||    |.| ..|   | | |
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPT-DIFMVMEYVSGGELFDYIVKHGRLQE

DVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQSIPYQPKVYDIWSLGVILYIMV
. |.. | |  |.| |||.. ||||||| ||||||.. |||. ||| |. .   . |   | || |||  |||||. .. .|     |||| ||||| |.
REACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMM---KDG-EFL-KTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAML

CGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHIDEILSHSWL
||  | ||.....  .  |. ..  |  |.|. |.|||| .|||.|  .|. |..|  |.|.
CGYLPFDDENTPTLYKKIKNGEYYIP--KFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase TSSK2.AA NuaK 12-272 39 5.1e-85 223.36 In-house 1-252 (252) Show / Hide 
Range on Protein: 12-272
Range on HMM: 1-252/252
Sequence Identity: 39% (104 aa)

YIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHED
| .   |||| | ||| |. .     ||.| | ..|   .   .   ||  |. ..||  ||. ||.|| .| .| |.||   .|.| ..|   . | | 
YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKD-KIVIVMEYASGGELYDYISECKSLPER

VARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQSIPYQ-PKVYDIWSLGVILYIMV
 ||..|||  ||| |||   |.||||| || |||.. |.|  ||| |     | .    . .|||||  || ||.    ||. | | | |||||.||.||
EARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSN-YYHDQK----FLHTFCGSPLYASPEIVNGQPYHGPEV-DCWSLGVLLYTMV

CGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHIDEILSHSWL
 |.||.| .| ... .  .. .   |.     |.   ||  ||. .  .|  | .| .| |.
YGTMPFDGHDFKHLVKQISQGAYYEPCKPSDACM---LIRWMLMVNPRRRATIYDICHHWWV
Kinase TSSK2.AA QIK 12-272 34 2.4e-76 259.93 In-house 1-272 (272) Show / Hide 
Range on Protein: 12-272
Range on HMM: 1-272/272
Sequence Identity: 34% (98 aa)

YIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGA----
| ..  .||| .| || |     |  ||.||||. .   .  ..   ||  |.   .|  ||| |.. || |  .||..|   .|.. . .  .|     
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQKCY-REVQIMKMLYHPHIIKLYQVMETDD-MMYIVTEYCSNGEMFDYLCKHGRKGVK

----------------LHEDVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQSIP
                . |..||..| |. |||.|||.. ||||||| ||.|||.. |||. |||||     .      | .|.||| .|||||... . 
MVNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQ-----LLMTWCGSPPYAAPEMFEGKE

YQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHIDEILSHSWL
|     ||||.||.||..|||..|.| . . .. .   . ..  | .  .  .| .|| .||  | ..|. |. |. | |.
YDGPKVDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFF--MSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase TSSK2.AA Pkinase 12-272 29 4.7e-74 257.13 Pfam 1-293 (293) Show / Hide 
Range on Protein: 12-272
Range on HMM: 1-293/293
Sequence Identity: 29% (89 aa)

YIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLP-REMDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQG----DLLEFIK--C
| .|  .|.||...|. ..       ||||||.....  .. .. .  .|  |.. .||  |...|..||. ...||..||.   |    || ..|.   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYISTWR

QGAL--HEDVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLDKDFNI----KLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQ-SIPYQPKVY
.|..   |........|. ....|||.  |.||||| ||.|.|.. .|    |..|||..|      . .    .||||.  |.||||.. . .| ||| 
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV-

DIWSLGVILYIMVCGSMPYDDS------DIRKMLRIQKEHRVDFPRSKNLT-------------------CECKDLIYRMLQPDVSQRLHIDEILSHSWL
|.||.|.|||.|.||  |....      | ..|..  .. ...|....  .                    ||||.|...|..| ..|. ...|| | |.
DMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase TSSK2.AA Ciliate-E2 12-272 25 1.9e-70 240.38 In-house 1-365 (365) Show / Hide 
Range on Protein: 12-272
Range on HMM: 1-365/365
Sequence Identity: 25% (95 aa)

YIVGINLGKGSYAKVKSA--YSERLKFN---------------------VAVKIIDRKKTPTDFVERFLPREMD----------ILATVNHGSIIKTYEI
|..   .|.|....|. .  .... .|.                     .|.||.  ..    . |  . ||..          || ..||  ||| || 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FET-SDGRIYIIMELGVQGDLLEFIK--CQ---------GALHEDVARKMFRQLSS---------------AVKYCHDLD-IVHRDLKCENLLLDKDFNI
|.. .|  ||..||.  .|||...||  ..         . . |  ......|. .               |..|.|    |.|||.| ||.|.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLSDFGFSKRCLRDSNGRII---------------------------LSKTFCGSAAYAAPEVLQSIPY--------QPKVYDIWSLGVILYIMVCGSMP
|..|||.||..  |.. |..                           . .|.||.. | |||.|.. .|          .  ||||||||||.|..|  |
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

YDDSDIRKMLRIQKEHRVDFP----------------RSKNLTCECKDLIYR----MLQPDVSQRLH-IDEILSHSWL
.        ....|.  .|||                  |... |||||| .    ||| | ..|.  ...|| | |.
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase TSSK2.AA Ciliate-E2-Unclassified 12-272 24 1.4e-64 220.89 In-house 1-352 (352) Show / Hide 
Range on Protein: 12-272
Range on HMM: 1-352/352
Sequence Identity: 24% (85 aa)

YIVGINLGKGSYAKVKSAYSERLKFNV-----AVKIIDRKKTPTDFVERFLPREMDILAT-----------------VNHGSIIKTYEIFE-TSDGRIYI
|...  .|.|...||. .. .  |  .     . ||...|.    ...  . .||...                   .|| .... ..... ...  |||
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

IMELGVQGDLLEFIK-----------------CQGALHEDVAR-----KMFRQLSSAVKYCHDLD-IVHRDLKCENLLLDKD---FNIKLSDFGFSKRCL
.||.  .|||...||                 ..  . |  |.     ..|.|. .. .|.|    |.|||.|.||.|.|..   ..||..|||.||.  
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

RDSNG-----------RIILSKTFCGSAAYA----APEVLQS-IPYQP--KVYDIWSLGVILYIMVCGSMPYDDSDIRK----------------MLRIQ
 ..|            .  ...||||.  |     ||||||.  ....  .  |||||||||| |. |  |..| .  .                .....
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

KEHRVDFPRSKN------LTCECKDLIY----RMLQPDVSQRLHIDEILSHSWL
|.  ..|| ...      .  |.||.|     .||. . ..|. ...|| | |.
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase TSSK2.AA ULK 12-272 30 1.4e-63 217.56 In-house 1-329 (329) Show / Hide 
Range on Protein: 12-272
Range on HMM: 1-329/329
Sequence Identity: 30% (99 aa)

YIVGINLGKGSYAKVKSAYSERLK----FNVAVKIIDRKKTPTDFVER-------FLPREMDILATVN--------HGSIIKTYEIFETSDG-RIYIIME
|..   |||||..||  .. .. |      ||.|.||..|   .  |.       .| .| .|. . .        |  |.| |..||||.   ||||||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LGVQGDLLEFIKCQGALHEDV----------ARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLDKDFN------------IKLSDFGFSKRCLRD-SNGR
.  .||| ..|| .. | ||.          |.. |.|. .. |. |.  |.|||.| .| |.....             .|..||||.| .  |  . .
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

IILSKT----FCGSAAYAAPEVLQ----SIPYQPKVYDIWSLGVILYIMVCGSMP---YDDSDIR-----KMLRIQKEHR-------VDFP---RSKNLT
.... .    .||.  | ||..||     .||  .  ||||||.|.| |. |  |   .  .|       | ........        .||    .... 
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

CECKDLIYRMLQPDVSQRLHIDEILSHSWL
 ||||||.|||| | ..|  ..|...| |.
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase TSSK2.AA TyrKc 12-272 21 2.7e-15 24.67 SMART 1-280 (280) Show / Hide 
Range on Protein: 12-272
Range on HMM: 1-280/280
Sequence Identity: 21% (64 aa)

YIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATV--NHGSIIKTYEIFETS------DGRIYIIMELGVQGDLLEFI-
   |  || | . .|  .       .|||| .   .     .| |. ||. |.  .  .|  |.. | .  ..      .. ..|.||.   |||.... 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFM-REARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KCQGALHEDVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRD-----SNGRIIL----SKTFCGSAAYAAPEVLQSIPYQ
|... |  .   ..  | ..   | |.  ..|||| . | |..... .| |||| |.    |     |   .      .. .       |||...   . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

PKVYDIWSLGVILY-IMVCGSMPYDD------SDIRKMLRIQKEHRVDFPRSKN------LTCECKDLIYRMLQPDVSQRLHIDEILSHSWL
.|  |.|| || .. |.  | .|| .      |... . .... .| . | .         . |  ... .  . | ..|    ||  |. .
TKS-DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase TSSK2.AA Pkinase_Tyr 12-156 25 3.8e-11 38.37 Pfam 1-156 (270) Show / Hide 
Range on Protein: 12-156
Range on HMM: 1-156/270
Sequence Identity: 25% (40 aa)

YIVGINLGKGSYAKVKSAYSE----RLKFNVAVKIIDRKKTPTD-FVERFLPREMDILATV-NHGSIIKTYEIFETSDGR--IYIIMELGVQGDLLEFIK
 . |  ||.|.. .|. ..        |  ||||..  . .. . . | |.  |. |. .  .|  |.. | .    ..   |||.||.   ||||.. .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

C----QGALHEDVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFG
     ...|      .| .| ...  | ..  ..|||| . | |..... .| .|||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG