Gene TSSK1 (Human)

TSSK1

Species: Human
Alias: FKSG81, TSSK1B, STK22D, SPOGA4, TSSK1
External Links: iHOP , Entrez Gene , Refseq cDNA , Refseq Protein , GeneCards
Annotation: Consensus chromosomal location: 5q22.2,

Classification

Group: CAMK
Family: TSSK

Sequence

Name Sequence Type Origin Length Description Download
TSSK1.NA RNA Sugen Kinome 2478 None Fasta, JSON
TSSK1.AA Protein Sugen Kinome 367 None Fasta, JSON
TSSK1.kin_dom Protein Kinase Domain Sugen Kinome 261 None Fasta, JSON

Protein domain

Protein domains of TSSK1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase TSSK1.AA TSSK 12-272 58 4.90000000001e-196 648.92 In-house 1-289 (289) Show / Hide 
Range on Protein: 12-272
Range on HMM: 1-289/289
Sequence Identity: 58% (170 aa)

YLLGINLGEGSYAKVKSAYSERLKFN----------------VAIKIIDRKKAPADFLEKFLPREIEILAM-LNHCSIIKTYEIFETSHGKVYIVMELAV
| .|...|.||||||..|||.. |..                ||||||||||||.|.|.|||||||.|... |.|..||..||.|||..||.|.|||.|.
YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIKIIDRKKAPTDYLNKFLPREIQIMRKTLKHPNIIQFYEMFETCQGKIYMVMEYAE

QGDLLELIKTR------GALHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRM-ALSKTFCGSPAYAAPEVL
.||||| |..|      |||||..||| |.|.. |.||||...|||||||| |.||||..||||.|| |.... |||.||.  |||||||| ||||||.|
HGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKHWNIKLTDFGFARYWPRDDPGRCCHLSKTFCGSYAYAAPEIL

QGIPYQPKVYDIWSLGVILYIMVCGSMPYDD--SNIKKMLRIQKEHRVNFPR--SKHLTGECKDLIYHMLQPDVNRRLHIDEILSHCWM
.||||.||.||.||.||||||||||.||.||  |||.|||..|.||.|.||.  |.... ||||||.|||||....|.||.||..||||
RGIPYDPKWYDVWSMGVILYIMVCGCMPFDDDKSNIHKMLWQQQEHKVCFPKPHSCWISQECKDLIRHMLQPHPCNRPHINEICHHCWM
Kinase TSSK1.AA CAMK 17-272 26 6e-115 371.98 In-house 1-425 (425) Show / Hide 
Range on Protein: 17-272
Range on HMM: 1-425/425
Sequence Identity: 26% (114 aa)

NLGEGSYAKVKSAYSERLK------------FNVAIKIIDRKKAP-------------------------ADFLEKFLPREIEILAM-------LNHCSI
 ||.||..||| ..  . .              |||||||.||..                          .. .|...|||||. .       |.|  |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKTYEIFE------------TSHG-------KVYIVM---ELAVQG----DLLELIKTR---------------GALHEDEARKKFHQLSLAIKYCHDLD
|| ||..|            |          ..|.||   |..  |    ||.. |. .               | ..|.|||. |.|.  |..|||...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

VVHRDLKCDNLLLDKD-----------------FNIKLSDFSFSKRCLRDDSGRMA-------------------LSKTFCGSPAYAA-PEVLQG-----
.||||||..|.|||..                 .|||..|| |.... .... .|                    . |||||.|.|.| ||||.|     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------IPYQPKVYDIWSLGVILYIMVCGSMPYDDS-------------NIKKMLRIQKEHRVNFPRSK----------------------HLTGECK
        .|| ..  |.||.|||||||.|| .|....             |......  .. . .|| ..                      ... |||
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DLIYHMLQPDVNRRLHIDEILSHCWM
||| .|||.| ..|. |...|.| ||
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase TSSK1.AA CAMKL 12-272 39 1.1e-112 360.94 In-house 1-297 (297) Show / Hide 
Range on Protein: 12-272
Range on HMM: 1-297/297
Sequence Identity: 39% (120 aa)

YLLGINLGEGSYAKVKSAYSERL-KFNVAIKIIDRKKAP-ADFLEKF-----------LPREIEILAMLN---HCSIIKTYEIFETSH-----GKVYIVM
| .|  ||.||..||| |  .|. .  |||||||.||.   .. .|            . |||.|. |||   |  ||| ||..||.      .|.|.||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELAVQGD--LLELIKTRGA----LHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLDKDF--NIKLSDFSFSKRCLR--DDSGRMALSKTFCGSPA
|..  |.  |.. |. .|     ..|.|||. | |.  |..|||....||||.| .|.|||..   |||..|| ||  . .  . .|..   |||||||.
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQK--LKTFCGSPP

YAAPEVLQG--IPYQPKVYDIWSLGVILYIMVCGSMPYDDS--------NIKKMLRIQKEHRVNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDEILSHC
|.|||..||   ||  .  ||||.||||| |||| .| ||         || .........  ..|  .|.  .|.||| .|||.. ..|  |..|..| 
YMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHP

WM
||
WM
Kinase TSSK1.AA MARK 12-272 39 1.1e-94 309.87 In-house 1-262 (262) Show / Hide 
Range on Protein: 12-272
Range on HMM: 1-262/262
Sequence Identity: 39% (106 aa)

YLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILAMLNHCSIIKTYEIFE--TSHGK-VYIVMELAVQGDLLELIKTR--G
| ..  .|.||||||| | . . . .|||||....|       | . |||||. .|.|  ||| ....|  |. .. .|..||.|  |.|.. || .  |
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTE-QHQIYLIMEYASGGELYDYIKAHPNG

ALHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLDKDF--NIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQPKVYDIWSLGV
 |||.|||. |.|.  |..|||. ..||||.|..|.|.|..   |||..|| || ..  .        .||||.|.|.|||.... ||  .  |||||||
RLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQK-----LNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGV

ILYIMVCGSMPYDDSN--IKKM-LRIQKEHRVNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDEILSHCWM
.||.||||. |.|...  .|..  .|...   ....  |.  ||..||  .|... ..|  |.||..| ||
VLYFMVCGYFPFDGDTQDYKELYKKILRG---KYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase TSSK1.AA NuaK 12-272 39 2e-87 229.81 In-house 1-252 (252) Show / Hide 
Range on Protein: 12-272
Range on HMM: 1-252/252
Sequence Identity: 39% (105 aa)

YLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKK--APADFLEKFLPREIEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALH
| .   ||.| | ||| |. .     |||| | ..|  ...| .     |||||.  |||  ||. ||.|| .  |. |||| | .|.| . |  .. | 
YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVH--IRREIEIMSSLNHPHIIHIYEVFENKD-KIVIVMEYASGGELYDYISECKSLP

EDEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQ-PKVYDIWSLGVILYI
| |||. | |   |. |||   ..|||||  | |||.. |.|  ||  |     ..     . .|||||| || ||.  | ||. | | | |||||.||.
EREARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQK-----FLHTFCGSPLYASPEIVNGQPYHGPEV-DCWSLGVLLYT

MVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDEILSHCWM
|| |.||.| .. |.. .  .. .   |.      .   || .||. . .||  | .| .| |.
MVYGTMPFDGHDFKHLVKQISQGAYYEPCK---PSDACMLIRWMLMVNPRRRATIYDICHHWWV
Kinase TSSK1.AA S_TKc 12-272 32 4.2e-87 296.59 SMART 1-231 (231) Show / Hide 
Range on Protein: 12-272
Range on HMM: 1-231/231
Sequence Identity: 32% (89 aa)

YLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQ--GDLLELIKTRGA--
| ..  .|.|...||. ..  . .  ||||||.          . . |||.|| . .|  |.| |..|..  ...|.|||.. .  |||...|| ||   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQPKVYDIWSLG
    ..| .||. ..|. .|..|||.. ..||||| .|.|||.  .||..|| ....            .||||.| | |||||   .| ..  |.||.|
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCG

VILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDEILS-------HCWM
.|||.|.||  |..  ....|... .            . |.||.| ..|| | ..|. . |.|        | |.
CILYEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase TSSK1.AA AMPK 12-272 40 8.3e-87 257.74 In-house 1-254 (254) Show / Hide 
Range on Protein: 12-272
Range on HMM: 1-254/254
Sequence Identity: 40% (107 aa)

YLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILAMLNHCSIIKTYEIF-ETSHGKVYIVMELAVQGDLLELIKTRGALHE
|..| ..|||.. ||| .. .. .  |||||....|   .   . . |||.|| ...| .||. ||.  ||     ..||| .  |.| . |  .| | |
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPT-DIFMVMEYVSGGELFDYIVKHGRLQE

DEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQPKVYDIWSLGVILYIMV
.||.. | |   .. |||.. .||||||  |||||.. |||. ||  |. .   .     . || |||| |||||. .| .|     |||| ||||| |.
REACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGE-----FLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAML

CGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDEILSHCWM
||  | ||.|. .  .  |. ..  |  |.|. |.|||| ||||.| . |. |..|  | | 
CGYLPFDDENTPTLYKKIKNGEYYIP--KFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase TSSK1.AA QIK 12-272 36 3.9e-84 285.84 In-house 1-272 (272) Show / Hide 
Range on Protein: 12-272
Range on HMM: 1-272/272
Sequence Identity: 36% (102 aa)

YLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGA----
| ..  .| | .| || |     |  |||||||. .  .. |.|   ||..|. ||.|  ||| |.. ||     |||.| . .|.. . .   |     
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQKCY-REVQIMKMLYHPHIIKLYQVMETDD-MMYIVTEYCSNGEMFDYLCKHGRKGVK

----------------LHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIP
                . |.|||..| |. .|..|||.. .||||||  |.|||.. |||. || ||     .     .| .|.||||.|||||...|. 
MVNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQG-----QLLMTWCGSPPYAAPEMFEGKE

YQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDEILSHCWM
|     ||||.||.||..|||..|.| ...... .   . ..  | .  .  .| .|| |||  | ..|. |. |. | ||
YDGPKVDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFF--MSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase TSSK1.AA Pkinase 12-272 29 1.8e-69 241.89 Pfam 1-293 (293) Show / Hide 
Range on Protein: 12-272
Range on HMM: 1-293/293
Sequence Identity: 29% (89 aa)

YLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLP-REIEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQG----DLLELIK--T
| .|  .|.||...|. ..       ||.|||.....  ....  .  .||.|...|||. |...|..||. ....|.|||..  |    || ..|.   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYISTWR

RGAL--HEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLDKDFNI----KLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQ-GIPYQPKVY
.|..   |.|... . |.  ...|||.  ..||||| .|.|.|.. .|    |..|| ..|        .    .||||.| |.||||.. | .| ||| 
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV-

DIWSLGVILYIMVCGSMPYDDS------NIKKMLRIQKEHRVNFPRSKHLT-------------------GECKDLIYHMLQPDVNRRLHIDEILSHCWM
|.||.|.|||.|.||  |....      . ..|..  .. .. |....  .                    ||||.|. .|..| ..|. ...|| | |.
DMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase TSSK1.AA Ciliate-E2 12-272 24 4.8e-68 232.38 In-house 1-365 (365) Show / Hide 
Range on Protein: 12-272
Range on HMM: 1-365/365
Sequence Identity: 24% (94 aa)

YLLGINLGEGSYAKVKSA--YSERLKFN---------------------VAIKIIDRKKAPADFLEKFLPREIE----------ILAMLNHCSIIKTYEI
| .   .|.|....|. .  .... .|.                     .|.||.  ..  . . |. . |||.          ||  |||  ||| || 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FET-SHGKVYIVMELAVQGDLLELIKTR-----------GALHEDEARKKFHQLSL---------------AIKYCHDLD-VVHRDLKCDNLLLDKDFNI
|.. .  ..|.|||.. .|||...|| .           . . | |... . |.                 |..|.|    ..|||.| .|.|.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLSDFSFSKRCLRD------DSGRM---------------------ALSKTFCGSPAYAAPEVLQGIPY--------QPKVYDIWSLGVILYIMVCGSMP
|..|| .||..  |       ...                       . .|.||.| | |||.|.| .|          .  ||||||||||.|..|  |
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

YDDSNIKKMLRIQKEHRVNFP----------------RSKHLTGECKDLIYH----MLQPDVNRRLH-IDEILSHCWM
.        ....|.  ..||                  |... ||||||      ||| | . |.  ...|| | |.
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase TSSK1.AA ULK 12-272 29 3.6e-67 229.46 In-house 1-329 (329) Show / Hide 
Range on Protein: 12-272
Range on HMM: 1-329/329
Sequence Identity: 29% (98 aa)

YLLGINLGEGSYAKVKSAYSERLK----FNVAIKIIDRKK--APA-----DFLEKFLPREIEILAMLN--------HCSIIKTYEIFETSHG-KVYIVME
| |   ||.||..||  .. .. |      ||.|.||..|          ... ..| .||.|. .|.        |. |.| |..||||.   .||.||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LAVQGDLLELIKTRGA----------LHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLDKDFN------------IKLSDFSFSKRCLRD-DSGR
.  .||| ..||...           | |.||.. |.|.  . |. |.  ..|||.| .| |.....             .|..|| |.| .  | .. .
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

MALSKT----FCGSPAYAAPEVLQ----GIPYQPKVYDIWSLGVILYIMVCGSMP----YDDSN---IKKMLRIQKEHR-------VNFP---RSKHLTG
|... .    .||.| | ||..||    ..||  .  ||||||.|.| |. |  |    . | .   |.| ........        .||    ....  
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISP

ECKDLIYHMLQPDVNRRLHIDEILSHCWM
||||||. ||| | . |  ..|...| |.
ECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase TSSK1.AA ULK 12-272 29 1.2e-63 217.8 In-house 1-324 (324) Show / Hide 
Range on Protein: 12-272
Range on HMM: 1-324/324
Sequence Identity: 29% (97 aa)

YLLGINLGEGSYA-KVKSAYSERL---KFNVAIKIID---RKKAPA----DFLEKFLPREIEILAMLN------HCSIIKTYEIFETSHG-KVYIVMELA
| |   ||.||.. ||  .. ..    .  ||.|.||    .| .     ... ..| .||.|. .|.      |  |.| |..||||.   .||.||. 
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNH-HIVKLYDWFETSNHNNIYIIMEYC

VQGDLLELIKTRGA---------LHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLDKDFN------------IKLSDFSFSKRCLRDDSGRMALS
 .||| ..||...          | |.||.. |.|.  . |. |.  ..|||.| .|.|. ...             .|..|| |.| .  ..   . . 
NGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMC-

KTFC------GSPAYAAPEVLQ----GIPYQPKVYDIWSLGVILYIMVCGSMP----YDDSN--IKKMLR-------IQKEHRVNFP---RSKHLTGECK
.|..      |.| | ||..||    ..||  .  ||||||.|.| |. |. |    . | .  |.|...       . |   ..||    ....  |||
QTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECK

DLIYHMLQPDVNRRLHIDEILSHCWM
|||. ||| | . |  ..||..| |.
DLIRRMLQYDEKDRISWEEIFNHPWF
Kinase TSSK1.AA TyrKc 12-271 23 1.1e-14 14.68 SMART 1-280 (280) Show / Hide 
Range on Protein: 12-271
Range on HMM: 1-280/280
Sequence Identity: 23% (67 aa)

YLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILAML--NHCSIIKTYEIFETSH------GKVYIVMELAVQGDLLELIK
  ||  |||| . .|  .       .||.| .   .     .| |. ||..|. .|  .|  |.. | .  ..       . ..||||..  |||.. ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFM-REARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

TRGA-LHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRD-------DSGRMAL--SKTFCGSPAYAAPEVLQGIPYQ
 ..  |  ..  .  .| .    | |.  ..|||| . | |..... .| |||  |.    |       |  |..   .. .       |||...   . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

PKVYDIWSLGVILY-IMVCGSMPYDD------SNIKKMLRIQKEHRVNFPRS------KHLTGECKDLIYHMLQPDVNRRLHIDEILSHCW
.|  |.|| || .. |.  | .|| .      ||.  . .... .|   | .       . . |  ...    . | . |    ||  .|.
TKS-DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase TSSK1.AA Pkinase_Tyr 12-155 25 1.5e-11 39.75 Pfam 1-155 (270) Show / Hide 
Range on Protein: 12-155
Range on HMM: 1-155/270
Sequence Identity: 25% (40 aa)

YLLGINLGEGSYAKVKSAYSE----RLKFNVAIKIIDRKKAPAD--FLEKFLPREIEILAML-NHCSIIKTYEIFETSHGK--VYIVMELAVQGDLLELI
  .|  ||||.. .|. ..        |  ||.|.. . .|  .  ..|.|.  |..|.  | .|  |.. | .     .   .|||||..  ||||.  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

KT----RGALHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDF
..    ...|   .  .  .| . .  | ..   .|||| . | |..... .| .||
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDF