Gene SSTK (Human)
SSTK
Sequence
Protein domains of SSTK.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | SSTK.AA | TSSK | 12-267 | 46 | 5.6e-176 | 582.07 | In-house | 1-289 (289) | Show / Hide |
Range on Protein: 12-267 Range on HMM: 1-289/289 Sequence Identity: 46% (136 aa) YKLGRTIGEGSYSKVKVATSKKYKGT----------------VAIKVVDRRRAPPDFVNKFLPRELSILRG-VRHPHIVHVFEFIEVCNGKLYIVMEAAA |..|..||.|||.||..|.|||.|.. ||||..||..||.|..|||||||..|.|. ..||.|....|..| |.|| |.||| |. YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIKIIDRKKAPTDYLNKFLPREIQIMRKTLKHPNIIQFYEMFETCQGKIYMVMEYAE T-DLLQAVQRN------GRIPGVQARDLFAQIAGAVRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGR-QAHGYPD----LSTTYCGSAAYASPEV . |||. .||. |... .||| .| |.. ||.|.|.|. |||||||||.||... ...|||||||.| .....|. ||.|.|||.|||.||. HGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKH-WNIKLTDFGFARYWPRDDPGRCCHLSKTFCGSYAYAAPEI LLGIPYDPKKYDVWSMGVVLYVMVTGCMPFDD--SDIAGLPRRQK-RGVLYPE--GLELSERCKALIAELLQFSPSARPSAGQVARNCWL |.|||||||.||||||||.||.||.||||||| |.| ....|. ..| .|. ....|..||.||...||..|..||........||. LRGIPYDPKWYDVWSMGVILYIMVCGCMPFDDDKSNIHKMLWQQQEHKVCFPKPHSCWISQECKDLIRHMLQPHPCNRPHINEICHHCWM |
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Kinase | SSTK.AA | CAMK | 17-267 | 21 | 4.8e-99 | 319.81 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 17-267 Range on HMM: 1-425/425 Sequence Identity: 21% (93 aa) TIGEGSYSKVKVATSKKYKGT------------VAIKVVDRRRAP-------------------------PDFVNKFLPRELSILRG-------VRHPHI |.|.||..||| .. |. .| ||||..|..... .. |...||..|.. ..||.| TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI VHVFEFIE------------VCNG-------KLYIVM---EAAAT-----DLLQAVQRN---------------GRIPGVQARDLFAQIAGAVRYLHDHH .. .|..| . ..|.|| | . ||.. .... ||.. .|| .| ||. ||.|.|.|. IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN LVHRDLKCENVLLSPDE----------------RRVKLTDFGFGRQAHG-----------------------YPDLSTTYCGSAAYAS-PEVLLG----- ||||||.||.||. .. .|..|||| .. . . .. .|.||. .|.. ||||.| IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN --------IPYDPKKYDVWSMGVVLYVMVTGCMPFDDS-------------DIAGLPRRQKRGVLY-P-----------------------EGLELSERC .||...| |.||.||.||.|..|..||... .. | .. ..| . | . ..|. | MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHH-FVSQEC KALIAELLQFSPSARPSAGQVARNCWL | || .|| |. |... |. . |. KDLIRKMLQVDPEKRMTIEQCLNHPWM |
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Kinase | SSTK.AA | CAMKL | 12-267 | 33 | 5.2e-98 | 313.38 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 12-267 Range on HMM: 1-297/297 Sequence Identity: 33% (102 aa) YKLGRTIGEGSYSKVKVATSKKY-KGTVAIKVVDRRRAP-PDFVNKF-----------LPRELSILRGVR---HPHIVHVFEFIE------VCNGKLYIV |..|.|.|.||..||| || ... . ||||..|.... ....| . || .|.. .. ||.|.. .| || .|.|.| YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIET-KKIYLV MEAAATD---LLQAVQRN----GRIPGVQARDLFAQIAGAVRYLHDHHLVHRDLKCENVLLSPDER-RVKLTDFGFGRQ---A-HGYPDLSTTYCGSAAY || . |.. .... ||.| .|| .| || || |.|.|. ||||.| ||.||. . . .|..||||. . |. .. .| ||| .| MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY ASPEVLLG--IPYDPKKYDVWSMGVVLYVMVTGCMPFDDS--------DIAGLPRRQKRGVLYP-EGLELSERCKALIAELLQFSPSARPSAGQVARNCW ..||...| ||| .| |.||.||.||.||.| .|||| .| | .....| || ...| .|. || .|| |. ||.. |. . | MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPW L . M |
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Kinase | SSTK.AA | S_TKc | 12-267 | 31 | 4.9e-84 | 286.4 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 12-267 Range on HMM: 1-231/231 Sequence Identity: 31% (85 aa) YKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRELSILRGVRHPHIVHVFEFIEVCNGKLYIVMEAAAT---DLLQAVQRNGR-- |...|.||.|...||. .. || . ||||... . . ||..||. .||.||. ..... ..||.||| . . ||.. ...|| YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHG ----IPGVQARDLFAQIAGAVRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGRQAHGYPDLSTTYCGSAAYASPEVLLGIPYDPKKYDVWSMGVVL .| .|| ...||. |. |.|.|. .||||| ||.||. ..|..|||. || ||.||. | .|||| .|...| |.|| |..| LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL YVMVTGCMPFDDSDIAGLPRRQKRGVLYPEGLELSERCKALIAELLQFSPSARPSAGQVAR-------NCWL | |..|. ||. . . . .. |. .| .| .||. |. ||.| .. . |. YEMLCGYPPFP------QMQMMFKKIG-------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | SSTK.AA | MARK | 12-267 | 36 | 7.4e-84 | 273.99 | In-house | 1-262 (262) | Show / Hide |
Range on Protein: 12-267 Range on HMM: 1-262/262 Sequence Identity: 36% (97 aa) YKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVN-KFLPRELSILRGVRHPHIVHVFEFIE-VCNGK-LYIVME-AAATDLLQAVQRN--G ||...|||.|||.|||.|..|... ||||.... . |. . | . ||..|.. . ||.|. |. || ... .|..|| | ..|.. .. | YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFK-LNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNG RIPGVQARDLFAQIAGAVRYLHDHHLVHRDLKCENVLLSPDE-RRVKLTDFGFGRQAHGYPDLSTTYCGSAAYASPEVLLGIPYDPKKYDVWSMGVVLYV |.. || .| || || |.|... ||||.|.||.|. . . .|..||||... |.| ||. .|..||..|. ||| .| |.||.|||||. RLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTF-CGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYF MVTGCMPFDDSD--IAGLPRRQKRGVLY-PEGLELSERCKALIAELLQFSPSARPSAGQVARNCWL ||.|. |||... . | .. ||. | .| |. || ||.. |. ||.. .. . |. MVCGYFPFDGDTQDYKELYKKILRGKYDIPCH--VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM |
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Kinase | SSTK.AA | Pkinase | 12-267 | 26 | 6.2e-72 | 250.09 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 12-267 Range on HMM: 1-293/293 Sequence Identity: 26% (80 aa) YKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLP-RELSILRGVRHPHIVHVFEFIEVCNGKLYIVMEAAAT-----DLLQAVQ--R |..||.||.||...|. .. |.. .||.|....|.. ... . .|..|.. ..||.|| ... | ....|.||| . || .. | YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYISTWR NGRI--PGVQARDLFAQIAGAVRYLHDHHLVHRDLKCENVLLSPDERR---VKLTDFGFGRQ--AHGYPDLSTTYCGSAAYASPEVLLGIPYDPKKYDVW .|.. . .... . ||. .. |.|.. .||||| ||.|.. . ||..|||. .| .. ||.||. |..|||..| .|...| |.| HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS--MTTFCGTPWYMAPEVIRGGQYYGPKVDMW SMGVVLYVMVTGCMPFDDS-------DIAGLPRRQKRGVLYPEGLELS-------------------ERCKALIAELLQFSPSARPSAGQVARNCWL |.|..|| |..| ||... ... . |. .. . ... . | | || .| .|.. |. ||.| |. |. SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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Kinase | SSTK.AA | NuaK | 12-267 | 37 | 2.1e-70 | 184.11 | In-house | 1-252 (252) | Show / Hide |
Range on Protein: 12-267 Range on HMM: 1-252/252 Sequence Identity: 37% (96 aa) YKLGRTIGEGSYSKVKVATSKKYKGTVAIKVV--DRRRAPPDFVNKFLPRELSILRGVRHPHIVHVFEFIEVCNGKLYIVME-AAATDLLQAVQRNGRIP |.. .| |.| | ||| || .. |||| . .. ... | | || |. . ||||.|..| | . |. |||| |. .| . . ...| YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVH--IRREIEIMSSLNHPHIIHIYEVFENKD-KIVIVMEYASGGELYDYISECKSLP GVQARDLFAQIAGAVRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGRQAHGYPDLSTTYCGSAAYASPEVLLGIPYDPKKYDVWSMGVVLYVMVTG || .| ||. || | | | .||||| ||.|| .. .| ||| .. .|.||| |||||. | || | ||.||.||.|| | EREARHFFRQIVSAVHYCHKHRICHRDLKLENILLD-QNCNAKIADFGLS-NYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYG CMPFDDSDIAGLPRRQKRGVLYPEGLELSERCKALIAELLQFSPSARPSAGQVARNCWL |||| .| | . ..| | | . |. |. || ..|. | | . ... |. TMPFDGHDFKHLVKQISQGAYY-EPCKPSDACM-LIRWMLMVNPRRRATIYDICHHWWV |
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Kinase | SSTK.AA | AMPK | 12-267 | 35 | 7.1e-68 | 200.61 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 12-267 Range on HMM: 1-254/254 Sequence Identity: 35% (92 aa) YKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRELSILRGVRHPHIVHVFEFIEVCNGKLYIVMEAA-ATDLLQAVQRNGRIPGV | .| |||||.. |||..| . . ||||. .... . . . . ||..||. .|||||. .| | . ...||| . .| . ..||.. YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER QARDLFAQIAGAVRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGRQAHGYPDLSTTYCGSAAYASPEVLLGIPYDPKKYDVWSMGVVLYVMVTGCM .|. .|.|| .| |.|.| |||||| ||.|| .. ..|. ||| .. | ||| ||.||. | .| . |.|| ||.||.|. | EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLD-HNKNIKIVDFGLSNMMKDG-EFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYL PFDDSDIAGLPRRQKRGVLY-PEGLELSERCKALIAELLQFSPSARPSAGQVARNCWL ||||.... | .. | |. | |. ||...| || ..|| | | . .. |. PFDDENTPTLYKKIKNGEYYIPK--FLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF |
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Kinase | SSTK.AA | QIK | 12-267 | 33 | 8e-62 | 211.7 | In-house | 1-272 (272) | Show / Hide |
Range on Protein: 12-267 Range on HMM: 1-272/272 Sequence Identity: 33% (94 aa) YKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRELSILRGVRHPHIVHVFEFIEVCNGKLYIVME-AAATDLLQAVQRNGR---- | ..|||| | . ||.|. . | ||||..|. . . .| || |. .||||. .. .|. . .|||.| . .. .. .|| YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQKCY-REVQIMKMLYHPHIIKLYQVMETDD-MMYIVTEYCSNGEMFDYLCKHGRKGVK ----------------IPGVQARDLFAQIAGAVRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGRQAHGYPDL-STTYCGSAAYASPEVLLGIPYD .. .|| | ||. || |.|... |||||| ||.|| . .|. ||||. . ... |.||| .|| ||...|. || MVNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLD-NNMNIKIADFGFS--NWFKQGQLLMTWCGSPPYAAPEMFEGKEYD PKKYDVWSMGVVLYVMVTGCMPFDDSDIAGLPRRQKRG-VLYPEGLELSERCKALIAELLQFSPSARPSAGQVARNCWL | |.|||||||||.|.| .||| . . | .| | . | .|. | || | |. | . |. . |. GPKVDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIP--FFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM |
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Kinase | SSTK.AA | MELK | 12-267 | 33 | 3.7e-52 | 176.4 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 12-267 Range on HMM: 1-254/254 Sequence Identity: 33% (88 aa) YKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRELSILRGVRHPHIVHVFEFIEVCNGKLYIVME-AAATDLLQAVQRNGRIPGV |.. .|| | ..|||.|. ||||..|... |. . |. |. .|| || ... .|| . |...||| . ... . |. |. YEVHDEIGTGGFAKVKLACHILTNQMVAIKIMDKNQLGHDLPR--VKTEMDALKNLRHQHICQLYHYIETED-KIFMVMEYCPGGEMFDYIIRQDRLEEE QARDLFAQIAGAVRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGRQAHGYPDLS--TTYCGSAAYASPEVLLGIPYDPKKYDVWSMGVVLYVMVTG ..| .| || |. |.| ||||| ||.|. .. ..|| |||. .. | | | ||| ||| ||.. | | ||||||..|||.. | ETRHFFRQIVSAIAYVHSQGYAHRDLKPENLLFD-EDHHLKLIDFGLCAKTKGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCG CMPFDDSDIAGLPRRQKRGVLYPEGLELSERCKALIAELLQFSPSARPSAGQVARNCWL .|||| . . .. .|. | | || | |. ..|| | | | .. |. FLPFDDDNMMIMYKKIMSGC-YEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV |
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Kinase | SSTK.AA | ULK | 12-255 | 23 | 4.6e-48 | 165.87 | In-house | 1-317 (329) | Show / Hide |
Range on Protein: 12-255 Range on HMM: 1-317/329 Sequence Identity: 23% (75 aa) YKLGRTIGEGSYSKVKVATSKKYK----GTVAIKVVDRR--RAPP-----DFVNKFLPRELSILRGVR--------HPHIVHVFEFIEVCNG-KLYIVME | | . .|.||. || .. || | ||.|..|. . . .. ..| .| |.. ||.|| ... | | .||.|| YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME AAAT-DLLQAVQRNGR----------IPGVQARDLFAQIAGAVRYLHDHHLVHRDLKCENVLLSPDERR-----------VKLTDFGFGRQAHGY---PD || | ..|.. .. .|. | ||. . ..||.| .|||.| .|.|.. . .|..||||... . YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ LSTTYC------GSAAYASPEVLL----GIPYDPKKYDVWSMGVVLYVMVTGCMPFDDSDIAGLP-----RRQKRG-----------VLYP---EGLELS . .|. |. | .|..| ..||. .| |.||.|...| |..| || . . . . . . .| .. .| MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS ERCKALIAELLQFSPSAR . || || .||. .. | PECKDLIRRMLQYDEKDR |
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Kinase | SSTK.AA | ULK | 12-255 | 23 | 1e-47 | 164.83 | In-house | 1-312 (324) | Show / Hide |
Range on Protein: 12-255 Range on HMM: 1-312/324 Sequence Identity: 23% (74 aa) YKLGRTIGEGSYS-KVKVATSKKY---KGTVAIKVVD------RRRAPP-DFVNKFLPRELSILRGVR---HPH--IVHVFEFIEVCNG-KLYIVMEAAA | | . .|.||. || .. || . ||.|..| . .. ..| .| .|.. ||. || ... | | .||.|| YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN T-DLLQAVQRN---------GRIPGVQARDLFAQIAGAVRYLHDHHLVHRDLKCENVLLSPDERR-----------VKLTDFGFGRQAHGY---PDLSTT || | ..| .|.. .|. | ||. . ..||.| .|||.| .| |.. . .|..||||... . .. .| GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT YC------GSAAYASPEVLL----GIPYDPKKYDVWSMGVVLYVMVTGCMPFDDSDIAGLP----------------RRQKRGVLYP--EGLELSERCKA .. |. | .|..| ..||. .| |.||.|...| |..| || . . . ... .. .. .|. || CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD LIAELLQFSPSAR || .||. .. | LIRRMLQYDEKDR |
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Kinase | SSTK.AA | Pkinase_Tyr | 12-156 | 27 | 4e-18 | 62.02 | Pfam | 1-156 (270) | Show / Hide |
Range on Protein: 12-156 Range on HMM: 1-156/270 Sequence Identity: 27% (45 aa) YKLGRTIGEGSYSKVKVATSK----KYKGTVAIKVVDRRRAPPD--FVNKFLPRELSILRGV-RHPHIVHVFEFIEVCN---GK--LYIVMEAAAT-DLL ..|...|||.. .|. .| | . | .||.|.. . | .. . .|. |..|.. .||.|| .. || . .||||| .. ||| ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMR-EAKIMKQLGHHPNIV---RLYGVCTDQGEPNQIYIVMEYMPHGDLL QAVQR----NGRIPGVQARDLFAQIAGAVRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFG .. ..... . . .||| . ||......|||| . |.|.. ... || .||| DYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVT-ENNVVKICDFG |
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Kinase | SSTK.AA | TyrKc | 12-266 | 19 | 1.1e-15 | 30.96 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 12-266 Range on HMM: 1-280/280 Sequence Identity: 19% (59 aa) YKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRELSILRGV--RHPHIVHVFEFIEVCN------GKLYIVME-AAATDLLQAVQ .||...||| . .| .| | .||.|.. . |. ||..|.. . .||.|| . . . |.|||| .. ||.. . ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFM-REARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR RNGR-IPGVQARDLFAQIAGAVRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGRQAHGY-------PDLSTTY--CGS----AAYASPEVLLGIPY .... .. . . ||| .|||.....|||| . |.|.. . .|| .||| | . . ... .| .||.. KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI----- DPKKY------DVWSMGVVLYVMVTGCMPFD-------DSDIAGLPRRQKRGVLYPEGL-------ELSERCKALIAELLQFSPSARPSAGQVARNCW ... |||| ||... . | ... |.. . . .... . . . .. .. . .. |. ||. .. . |. --NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF |