Gene NuaK2 (Human)

NuaK2

Species: Human
Alias: DKFZP434J037, NuaK2, DKFZp686F01113, SNARK, FLJ90349, NUAK2
External Links: iHOP , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , GeneCards
Annotation: Consensus chromosomal location: 1q31-q32.1,

Classification

Group: CAMK
Family: CAMKL
Subfamily: NuaK

Sequence

Name Sequence Type Origin Length Description Download
NuaK2.NA RNA Sugen Kinome 3504 None Fasta, JSON
NuaK2.AA Protein Sugen Kinome 672 None Fasta, JSON
NuaK2.kin_dom Protein Kinase Domain Sugen Kinome 251 None Fasta, JSON

Protein domain

Protein domains of NuaK2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase NuaK2.AA NuaK 97-347 79 1.1e-267 713.82 In-house 1-252 (252) Show / Hide 
Range on Protein: 97-347
Range on HMM: 1-252/252
Sequence Identity: 79% (200 aa)

YEFLETLGKGTYGKVKKARE-SSGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSERE
|||..|||||||||||.|.| |.||.||||||.|.||.||||..||||||||||||||||||.|.|||||..||||||||||.|.|||||||...|.|||
YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPERE

ARHFFRQIVSAVHYCHQNRVVHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEVDSWSLGVLLYILVHGTMPFD
||||||||||||||||..|..||||||||||||.|.|.|||||||||.||..|||.||||||||||||||||.||.|||||.||||||||..|.||||||
ARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMPFD

GHDHKILVKQISNGAYREPPKPSDACGLIRWLLMVNPTRRATLEDVASHWWV
|||.| ||||||.|||.||.||||||.||||.|||||.||||..|...||||
GHDFKHLVKQISQGAYYEPCKPSDACMLIRWMLMVNPRRRATIYDICHHWWV
Kinase NuaK2.AA CAMKL 97-347 44 1.2e-153 493.82 In-house 1-297 (297) Show / Hide 
Range on Protein: 97-347
Range on HMM: 1-297/297
Sequence Identity: 44% (135 aa)

YEFLETLGKGTYGKVKKARE-SS-GRLVAIKSIRKDKIKD-------------EQDLMHIRREIEIMSSLN---HPHIIAIHEVFENSSK------IVIV
|....|||||..|||| |.  .  |. |||| | |.||..             |.|. .|||||.||..||   ||.|| ..||.|....      |..|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

MEYASRGD--LYDYISER----QQLSEREARHFFRQIVSAVHYCHQNRVVHRDLKLENILLDANG--NIKIADFGLSNLYH-Q----GKFLQTFCGSPLY
|||.| |.  |.||| ..    . ..|.|||..||||||||.|||....||||.|.|||||| ||  ||||.|||.||.|  .    |..| |||||| |
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

ASPEIVNG--KPYTGPEVDSWSLGVLLYILVHGTMPFDGH--------DHKILVKQISNGAYREPPK---PSDACGLIRWLLMVNPTRRATLEDVASHWW
..|||..|  ||| ||.|| ||.||.|| .| |..|||.         ..  | ..|  | |..|.    . |.  |||..|.|||..|.|.... .|.|
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPW

V
.
M
Kinase NuaK2.AA CAMK 102-347 30 2.9e-135 438.63 In-house 1-425 (425) Show / Hide 
Range on Protein: 102-347
Range on HMM: 1-425/425
Sequence Identity: 30% (130 aa)

TLGKGTYGKVKKARES-SG------------RLVAIKSIRKDKIKD-------------------------EQDLMHIRREIEIMSS-------LNHPHI
|||.|..||||....  ..            . |||| | |.|.||                         ..|.  .|||||||..       |.||.|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IAIHEVFE------------NSSK--------IVIVM---EYASRG----DLYDYISERQQ---------------LSEREARHFFRQIVSAVHYCHQNR
| ..||.|            . ||        ...||   ||.| |    ||.||| |. .               ..|||||..||||.|||||||.. 
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

VVHRDLKLENILLDAN-----------------GNIKIADFGLSNLYHQ------------------------GKFLQTFCGSPLYAS-PEIVNG-----
.||||||.|||||| |                 .||||.|||..| . .                        |. ..||||.| |.. ||..||     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------KPYTGPEVDSWSLGVLLYILVHGTMPFDGH-------------DHKILVKQISNGAYR-EPPKPSD------------------------AC
        ||| ||..| ||.||.|||.. |..||.|              . . | ..| .| |. .||. |.                        . 
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

GLIRWLLMVNPTRRATLEDVASHWWV
 |||..| |.|..|.|.|.. .| |.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase NuaK2.AA MARK 97-347 50 1.4e-131 432.27 In-house 1-262 (262) Show / Hide 
Range on Protein: 97-347
Range on HMM: 1-262/262
Sequence Identity: 50% (131 aa)

YEFLETLGKGTYGKVKKARE-SSGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPHIIAIHEVFE--NSSK-IVIVMEYASRGDLYDYISER--QQ
|..| |.|.|.|.|||.|.   .|| |||| . | |. | | .  ..||||||..|.||.||  ..|.|  .... |...|||||.|.||||| ..    
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LSEREARHFFRQIVSAVHYCHQNRVVHRDLKLENILLDANG--NIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEVDSWSLGVLLYILV
|.|.|||..||||||||.|||....||||.|.||||.|.||  ||||.|||.|.    |. | ||||.| |..|||...|||.||.|| |||||.||..|
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

HGTMPFDGHD--HKILVKQISNGAYREPPKP-SDACGLIRWLLMVNPTRRATLEDVASHWWV
.|. |||| .   | | |.| .| |. |..   ..  ||..||.||| .|.|.|.. .| |.
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase NuaK2.AA AMPK 97-347 50 1.6e-128 383.66 In-house 1-254 (254) Show / Hide 
Range on Protein: 97-347
Range on HMM: 1-254/254
Sequence Identity: 50% (127 aa)

YEFLETLGKGTYGKVKKAR-ESSGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPHIIAIHEVF-ENSSKIVIVMEYASRGDLYDYISERQQLSER
|   .|.|.||.|||| .  .  |  |||| . |.||||...   |.|||.|. ...|||||   ||  |  . | .||||.| |.|.|||  .. |.||
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

EARHFFRQIVSAVHYCHQNRVVHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEVDSWSLGVLLYILVHGTMPF
||. || ||.|.| |||.. .||||||.||.|||.| ||||.||||||..  |.|| | |||| ||.||.. ||.| ||||| || || || .. |. ||
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

DGHDHKILVKQISNGAYREPPKPSDAC-GLIRWLLMVNPTRRATLEDVASHWWV
|  .   | | | || |  |   |. . .||. .| |.|. |.| .|.  | | 
DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase NuaK2.AA S_TKc 97-347 36 4.2e-106 359.71 SMART 1-231 (231) Show / Hide 
Range on Protein: 97-347
Range on HMM: 1-231/231
Sequence Identity: 36% (97 aa)

YEFLETLGKGTYGKVKKARESS-GRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPHIIAIHEVFENSSKIVIVMEYASR--GDLYDYISERQQ---
||.|...|||..|||.|.|. . ||.|||| |.           ||||||.|... .||.|. ...||.. ... .||||..   |||.||| .|.    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LSEREARHFFRQIVSAVHYCHQNRVVHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEVDSWSLGVLLYIL
   ..| .||....||..|. |||.....||||| ||||||   .|||.||||. ..       ||||.| | .||..   .|.....| ||.|..||..
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

VHGTMPFDGHDHKILVKQISNGAYREPPKPSDACGLIRWLLMVNPTRRATLEDVAS-------HWWV
. |  ||.  ... . |.|          ...|. .|| .| ..|..| |  ..         | |.
LCGYPPFP--QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase NuaK2.AA QIK 97-347 45 2.4e-105 356.29 In-house 1-272 (272) Show / Hide 
Range on Protein: 97-347
Range on HMM: 1-272/272
Sequence Identity: 45% (123 aa)

YEFLETLGKGTYGKVKKARESSGRL-VAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQ-----
|.   |.||| .. || ||       ||||.| | .. ||..|  . ||..|| .|.|||||   .| |  . . ||.||.| |...||. .  .     
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQL-DEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

---------------LSEREARHFFRQIVSAVHYCHQNRVVHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEV
               ..|.|||  | ||.|||||||.  .|||||| ||||||.| ||||||||.||.. ||. |.|.|||| || ||.  || |.||.|
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKV

DSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPKPSDAC-GLIRWLLMVNPTRRATLEDVASHWWV
| ||.||.||.|| | .||||   . | . .  | .| |.  |  |  |||  | |.|..| | . .  | | 
DIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase NuaK2.AA AGC 97-347 23 8.49999999999e-102 263.37 In-house 1-395 (395) Show / Hide 
Range on Protein: 97-347
Range on HMM: 1-395/395
Sequence Identity: 23% (93 aa)

YEFLETLGKGTYGKVKKARE-------SSGRLVAIKSIRKDK---IKDEQDLMHIRRE------------IEIMSSLN----------HPHIIA-IHEVF
.||| ..|||..|||  .|.       ..|.. |.| ..|..   ||..... |. .|             .|.. .|          || |.   |  |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

ENSSK--IVIVMEYAS---------RG-DLYDYIS---ERQQLSEREARHFFRQ-------IVSAVHYCHQ-NRVVHRD-LKLENILLDANGNIKIADFG
.. ..  . .||||..          | .|. ..     .. ..| .||... .       ||.|..| |. . ..||| ||.||||||..|.||..|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LS----------------------------------------------------NLYHQGKFLQTFCG--SPLYASPEIVNGKPYTGPEVDSWS--LGVL
|.                                                    .  ....  .||||  .| | .|||.      |...| ||  ||.|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTR-KKRDRTWTFCGPCTPEYMAPEIL-----YGKACDWWSFGLGCL

LYILVHGTMPFDGH----------DHKILVKQISNG-----AYREPPKP------------SDACGLIRWLLMVNPTRRAT----------LEDVASHWW
.| .. |  || |.          ... . ..| ||        . | |            ..|  ||. || ..|..| .           |.. .| |
MYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPW

V
 
F
Kinase NuaK2.AA Pkinase 97-347 34 3.1e-99 340.8 Pfam 1-293 (293) Show / Hide 
Range on Protein: 97-347
Range on HMM: 1-293/293
Sequence Identity: 34% (102 aa)

YEFLETLGKGTYGKVKKARESSGRL-VAIKSIRKDKIKDEQDLMHIR-REIEIMSSLNHPHIIAIHEVFENSSKIVIVMEYASRG----DLYDYIS--ER
|......|.|..|.|.|... . .  ||.| |.|...|...|  |.| .||.|| .||||.|. ....||....| .||||.  |    ||.||||  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

QQL--SEREARHFFRQIVSAVHYCHQNRVVHRDLKLENILLDANGNI----KIADFGLSNL--YHQGKFLQTFCGSPLYASPEIVNGKPYTGPEVDSWSL
  .  ||.|......||.... |||.....|||||.||||.| ||.|    ||.||||. .  |  .  ..||||.| |..||...| .| ||.|| ||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVLLYILVHGTMPFDGH------DHKILVKQISNGAYREP-PKP---------------------SDACGLIRWLLMVNPTRRATLEDVASHWWV
|..||... |  ||.||      |.. ....|  . .... |..                     .... .|.|.| ..|..| | |..  | |.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase NuaK2.AA TSSK 97-347 37 2.1e-92 303.56 In-house 1-289 (289) Show / Hide 
Range on Protein: 97-347
Range on HMM: 1-289/289
Sequence Identity: 37% (109 aa)

YEFLETLGKGTYGKVKKARESSGRLV-----------------AIKSIRKDKIKDEQDLMHIRREIEIMSS-LNHPHIIAIHEVFENSS-KIVIVMEYAS
|.. ...|.|.|.||..|.  . ..                  ||| | . | ...     . |||.||   |.||.|| ..| ||... || .|||||.
YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIKIIDRKKAPTDYLNKFLPREIQIMRKTLKHPNIIQFYEMFETCQGKIYMVMEYAE

RGDLYDYISER------QQLSEREARHFFRQIVSAVHYCHQNRVVHRDLKLENILLDANGNIKIADFGLSNLYHQGK------FLQTFCGSPLYASPEIV
.||| .|| .|        |.| .|| .|||.|||| |||   |||||||.|||||| ..|||..||| ..    ..       ..|||||  ||.|||.
HGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKHWNIKLTDFGFARYWPRDDPGRCCHLSKTFCGSYAYAAPEIL

NGKPYTGPEVDSWSLGVLLYILVHGTMPFDG--HDHKILVKQIS--NGAYRE--PPKPSDAC-GLIRWLLMVNPTRRATLEDVASHWWV
 |.|| .  .| ||.|| |||.| |.||||   .... . .|..  . ....   .  |..|  ||| .|  .|..|........| |.
RGIPYDPKWYDVWSMGVILYIMVCGCMPFDDDKSNIHKMLWQQQEHKVCFPKPHSCWISQECKDLIRHMLQPHPCNRPHINEICHHCWM
Kinase NuaK2.AA BRSK 97-347 41 2.1e-81 276.72 In-house 1-254 (254) Show / Hide 
Range on Protein: 97-347
Range on HMM: 1-254/254
Sequence Identity: 41% (106 aa)

YEFLETLGKGTYGKVKK-ARESSGRLVAIKSIRKDKIK-DEQDLMHIRREIEIMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSER
|    |||||. |.||      .|. |||| | | |    |  || . ||| ||   .|||.. ...|.||.     ..|. | | |.||  ..  |  .
YRLEKTLGKGQTGLVKLGVHCVTGKKVAIKIINKEKLSNKESMLMKVEREIAIMKLIDHPHVMKMYDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPK

EARHFFRQIVSAVHYCHQNRVVHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEVDSWSLGVLLYILVHGTMPF
||| |||||.||. .||   . ||||| || |||   ||||||||.  |  ..  | | |||| ||.||.. |  | |   | || || || |  | .||
EARKFFRQIISALDFCHSHNICHRDLKPENLLLDEKNNIKIADFGMASLQVKDMMLHTSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALPF

DGHDHKILVKQISNGAYREPP-KPSDACGLIRWLLMVNPTRRATLEDVASHWWV
|      |   . .|..  |.  . |.  | | .. |.| .| .|...  | |.
DDDNLRQLLEKVKRGVFHMPHFIHPDCQDLLRGMIEVDPDKRISLKEIQKHPWY
Kinase NuaK2.AA Ciliate-E2 97-347 25 2.1e-79 270.11 In-house 1-365 (365) Show / Hide 
Range on Protein: 97-347
Range on HMM: 1-365/365
Sequence Identity: 25% (96 aa)

YEFLETLGKGTYGKVKKARE------------------------SSGRLVAIKSIRKDKIKDEQDLMHIRREIE----------IMSSLNHPHIIAIHEV
|.|.. .|.|..|.|.|..                           . ..|.|...|..|.      || |||.          |...||||.|| ..|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE--NSSKIVIVMEYASRGDLYDYISER-----------QQLSEREARHFFRQIVS---------------AVHYCHQNR-VVHRDLKLENILLDANGNI
|.  . ..| .||||.. |||.||| ..           ....|.|......||..               |..|.|..  ..|||.|.||||.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KIADFGLS----------------NLYHQGK-----------------FLQTFCGSPLYASPEIVNGKPYTG--------PEVDSWSLGVLLYILVHGTM
||.|||||                ..| . |                   .|.||.| | .|||.|||.|..         ..| |||||.||... |  
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFDGHDHKILVKQISNGAYREPPK-------------------PSDACGLIRW----LLMVNPTRRAT-LEDVASHWWV
||         .|| .. .. |..                   . ..  ||.     .| ..|  | |  |..  | | 
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase NuaK2.AA Pkinase_Tyr 97-241 30 6.5e-33 112.09 Pfam 1-158 (270) Show / Hide 
Range on Protein: 97-241
Range on HMM: 1-158/270
Sequence Identity: 30% (49 aa)

YEFLETLGKGTYGKVKKARES-----SGRLVAIKSIRKDKIKDEQD--LMHIRREIEIMSSL-NHPHIIAIHEVFE-NSSK--IVIVMEYASRGDLYDYI
 .|...||.| .|.|.|..        .  ||.|.. |.   ....  .    ||..||..| .||.|.  . |    .    | |||||.  |||.|| 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

SE----RQQLSEREARHFFRQIVSAVHYCHQNRVVHRDLKLENILLDANGNIKIADFGLS
 .    .|.|.  .  .. .|| ..  | .... .||||   |.|.. |. .||.||||.
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase NuaK2.AA TyrKc 97-345 24 4.7e-27 97.13 SMART 1-280 (280) Show / Hide 
Range on Protein: 97-345
Range on HMM: 1-280/280
Sequence Identity: 24% (70 aa)

YEFLETLGKGTYGKVKKARESSGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSL--NHPHIIAIHEVFENS-------SKIVIVMEYASRGDLYDYISE
 .....|| | .|.| |.. .  . ||.|....|.      .. ..||..||..|  .||.|.... |   .         . |||||.. ||| ||. .
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

RQQ-LSEREARHFFRQIVSAVHYCHQNRVVHRDLKLENILLDANGNIKIADFGLSNLYHQG------KFLQTF----CG---SPL-YASPEIVNGKPYTG
..  |. ..  .|  || .   | |.....||||   |.|...|. .||.|||||   . .      |   .     .|    |.   .||  | . .| 
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT-

PEVDSWSLGVLLY-ILVHGTMPFDG-----HDHKILVKQISNGAYREPPKP-----------SDACGLIRWLLMVNPTRRATLEDVASHW
.. | || ||... |.  | .|  |      . . ..... .| ....|.                 ....  . .|  | | ... . .
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF