Gene NuaK1 (Human)

NuaK1

Species: Human
Alias: NuaK1, ARK5, KIAA0537, NUAK1
External Links: iHOP , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , GeneCards
Annotation: Consensus chromosomal location: 12q23.3-q24.2,

Classification

Group: CAMK
Family: CAMKL
Subfamily: NuaK

Sequence

Name Sequence Type Origin Length Description Download
NuaK1.NA RNA Sugen Kinome 6821 None Fasta, JSON
NuaK1.AA Protein Sugen Kinome 661 None Fasta, JSON
NuaK1.kin_dom Protein Kinase Domain Sugen Kinome 252 None Fasta, JSON

Protein domain

Protein domains of NuaK1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase NuaK1.AA NuaK 55-306 80 1.4e-271 724.25 In-house 1-252 (252) Show / Hide 
Range on Protein: 55-306
Range on HMM: 1-252/252
Sequence Identity: 80% (202 aa)

YELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHPHIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERE
||.|.|||||||||||.|||...||.||||||.|.||.||||||||||||||||||||||||.|||||||||||||.|||||.|||||||||...|.|||
YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPERE

TRHFFRQIVSAVHYCHKNGVVHRDLKLENILLDDNCNIKIADFGLSNLYQKDKFLQTFCGSPLYASPEIVNGRPYRGPEVDSWALGVLLYTLVYGTMPFD
.||||||||||||||||....||||||||||||.|||.|||||||||.|...|||.||||||||||||||||.||.|||||.|.|||||||.||||||||
ARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMPFD

GFDHKNLIRQISSGEYREPTQPSDARGLIRWMLMVNPDRRATIEDIANHWWV
|.|.|.|..|||.|.|.||..||||..||||||||||.|||||.||..||||
GHDFKHLVKQISQGAYYEPCKPSDACMLIRWMLMVNPRRRATIYDICHHWWV
Kinase NuaK1.AA CAMKL 55-306 47 8.49999999999e-161 516.99 In-house 1-297 (297) Show / Hide 
Range on Protein: 55-306
Range on HMM: 1-297/297
Sequence Identity: 47% (142 aa)

YELQETLGKGTYGKVKRATE-RFSGRVVAIKSIRKDKIKD-------------EQDMVHIRREIEIMSSLN---HPHIISIYEVFENKDK------IVII
|.. .|||||..|||| ||  |. |. |||| | |.||..             |.|| .|||||.||..||   ||.||..|||.|....      |...
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

MEYASKGE--LYDYISER----RRLSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLDDNC--NIKIADFGLSNLYQK-----DKFLQTFCGSPLY
|||.| ||  |.||| ..    .|..|.|.|..||||||||.|||..|.||||.|.||||||.|   ||||.|||.||.|..     ...| |||||| |
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

ASPEIVNG--RPYRGPEVDSWALGVLLYTLVYGTMPFDGF--------DHKNLIRQISSGEYREP--TQPSDARGLIRWMLMVNPDRRATIEDIANHWWV
..|||..|  .||.||.|| |..||.||..|.|..|||.         .. .| ..| .| |..|   ..||.| |||.||.|||..|.||..| ||.|.
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase NuaK1.AA CAMK 60-306 30 3.6e-141 457.99 In-house 1-425 (425) Show / Hide 
Range on Protein: 60-306
Range on HMM: 1-425/425
Sequence Identity: 30% (128 aa)

TLGKGTYGKVKRATERFSG------------RVVAIKSIRKDKIKD-------------------------EQDMVHIRREIEIMSS-------LNHPHI
|||.|..||||..... ..            . |||| | |.|.||                         ..|.  .|||||||..       |.||.|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

ISIYEVFE------------NKDK--------IVIIM---EYASKGEL----YDYISER---------------RRLSERETRHFFRQIVSAVHYCHKNG
|..|||.|            . .|        ....|   ||.| |||    .||| |.               .|..|||.|..||||.|||||||...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

VVHRDLKLENILLDDN-----------------CNIKIADFGLSNLYQK------------------------DKFLQTFCGSPLYAS-PEIVNG-----
.||||||.||||||||                 .||||.|||..| ...                        .. ..||||.| |.. ||..||     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------RPYRGPEVDSWALGVLLYTLVYGTMPFDGF-------------DHKNLIRQISSGEYR-EPTQPSD------------------------AR
        .|| ||..| |..||.||... |..||.|              . ..| ..| .|.|. .| . |.                        ..
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

GLIRWMLMVNPDRRATIEDIANHWWV
 |||.|| |.|..|.|||.. || |.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase NuaK1.AA AMPK 55-306 51 2.8e-139 416.09 In-house 1-254 (254) Show / Hide 
Range on Protein: 55-306
Range on HMM: 1-254/254
Sequence Identity: 51% (130 aa)

YELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHPHIISIYEVF-ENKDKIVIIMEYASKGELYDYISERRRLSER
| ...|.|.||.|||| .|    |  |||| . |.||||....  |.|||.|. ...|||||  |||  | .. | ..|||.| |||.|||  ..||.||
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

ETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLDDNCNIKIADFGLSNLYQKDKFLQTFCGSPLYASPEIVNGRPYRGPEVDSWALGVLLYTLVYGTMPF
|.. || ||.|.| |||....||||||.||.|||.| ||||.||||||.... .|| | |||| ||.||.. |..| ||||| |  || || .. |. ||
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

DGFDHKNLIRQISSGEYREPTQPSD-ARGLIRWMLMVNPDRRATIEDIANHWWV
|  .  .| . | .|||  |.  |. |..||. || |.|  |.||.|| || | 
DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase NuaK1.AA MARK 55-306 49 1.3e-137 452.25 In-house 1-262 (262) Show / Hide 
Range on Protein: 55-306
Range on HMM: 1-262/262
Sequence Identity: 49% (129 aa)

YELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHPHIISIYEVFE--NKDK-IVIIMEYASKGELYDYISER--RR
|..  |.|.|.|.||| |. . .|| |||| . | |. | | |  ..||||||..|.||.||. ..|.|  .. . |..||||||.||||||| ..  .|
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLDDNC--NIKIADFGLSNLYQKDKFLQTFCGSPLYASPEIVNGRPYRGPEVDSWALGVLLYTLV
|.|.|.|..||||||||.|||....||||.|.||||.|.|   ||||.|||.|.  . .. | ||||.| |..|||....|| ||.|| |.|||.||..|
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

YGTMPFDGFD--HKNLIRQISSGEYR-EPTQPSDARGLIRWMLMVNPDRRATIEDIANHWWV
 |. |||| .   |.| ..| .|.|.  .  . ..| ||...|.|||..|.|||.| .| |.
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase NuaK1.AA QIK 55-306 45 6.7e-114 384.69 In-house 1-272 (272) Show / Hide 
Range on Protein: 55-306
Range on HMM: 1-272/272
Sequence Identity: 45% (125 aa)

YELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHPHIISIYEVFENKDKIVIIMEYASKGELYDYISERRR-----
|..  |.||| .. ||.|. |     ||||.| | .. ||...  . ||..|| .|.|||||  |.| | .| . |..||.| ||..||. .  |     
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQL-DEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

---------------LSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLDDNCNIKIADFGLSNLYQKDKFLQTFCGSPLYASPEIVNGRPYRGPEV
               ..|.|.|  | ||.|||||||| ..|||||| |||||| | ||||||||.||...... |.|.|||| || ||.  |. | ||.|
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKV

DSWALGVLLYTLVYGTMPFDGFDHKNLIRQISSGEYREPTQ-PSDARGLIRWMLMVNPDRRATIEDIANHWWV
| | .||.|| || | .||||   .|| . . || .| |   ..|   ||| || |.|..| ||. | .| | 
DIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase NuaK1.AA S_TKc 55-306 34 6.7e-108 365.69 SMART 1-231 (231) Show / Hide 
Range on Protein: 55-306
Range on HMM: 1-231/231
Sequence Identity: 34% (93 aa)

YELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHPHIISIYEVFENKDKIVIIMEYASK--GELYDYISERRR---
||. ...|||..|||...... .||.|||| |.           ||||||.|... .||.|. .|.||.. |.. ..|||..   |.|.||| .|.|   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLDDNCNIKIADFGLSNLYQKDKFLQTFCGSPLYASPEIVNGRPYRGPEVDSWALGVLLYTL
   ..| ..|....||..|. |||..|..||||| ||||||.  .|||.||||. ..       ||||.| | .||..   .| ....| |..|..|| .
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

VYGTMPFDGFDHKNLIRQISSGEYREPTQPSDARGLIRWMLMVNPDRRATIEDIAN-------HWWV
..|  ||.  ... ....|          ...|. .|| .| ..|..| |. .. .       | |.
LCGYPPFP--QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase NuaK1.AA Pkinase 55-306 34 8.70000000001e-106 362.54 Pfam 1-293 (293) Show / Hide 
Range on Protein: 55-306
Range on HMM: 1-293/293
Sequence Identity: 34% (102 aa)

YELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIR-REIEIMSSLNHPHIISIYEVFENKDKIVIIMEYASKG----ELYDYIS--ER
|.. ...|.|..|.|...... .|..||.| |.|...|...|. |.| .||.|| .||||.|. .|..||.||.| ..|||. .|    .|.||||  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RRL--SERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLDDNCNI----KIADFGLSNL--YQKDKFLQTFCGSPLYASPEIVNGRPYRGPEVDSWAL
...  ||.| .....||.... |||..|..|||||.||||.|.|..|    ||.||||. .  | ..  ..||||.| |..||...|..| ||.|| |..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVLLYTLVYGTMPFDGF------DHKNLIRQISSGEYREPTQ----------------------PSDARGLIRWMLMVNPDRRATIEDIANHWWV
|..|| .. |  ||.|       |.. .|..| ....... .                      ..... .|.|.| ..| .| |.|.| .| |.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase NuaK1.AA TSSK 55-306 37 1.4e-98 324.13 In-house 1-289 (289) Show / Hide 
Range on Protein: 55-306
Range on HMM: 1-289/289
Sequence Identity: 37% (108 aa)

YELQETLGKGTYGKVKRATERFSGRV----------------VAIKSIRKDKIKDEQDMVHIRREIEIMSS-LNHPHIISIYEVFENKD-KIVIIMEYAS
|......|.|.|.||..|. .   .                 |||| | . | ...  .  . |||.||   |.||.|| .|| ||. . || ..||||.
YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIKIIDRKKAPTDYLNKFLPREIQIMRKTLKHPNIIQFYEMFETCQGKIYMVMEYAE

KGELYDYISER------RRLSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLDDNCNIKIADFGLSNLYQKDK------FLQTFCGSPLYASPEIV
 | | .|| .|      ..|.| ..| .|||.|||| |||  .|||||||.||||||.. |||..||| ..   .|.       ..|||||  ||.|||.
HGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKHWNIKLTDFGFARYWPRDDPGRCCHLSKTFCGSYAYAAPEIL

NGRPYRGPEVDSWALGVLLYTLVYGTMPFDG--FDHKNLIRQIS--SGEYRE---PTQPSDARGLIRWMLMVNPDRRATIEDIANHWWV
 |.|| .  .| |..|| ||..|.|.||||    ... ...|..  .  ...   ..  .... ||| ||  .| .|..|..|..| |.
RGIPYDPKWYDVWSMGVILYIMVCGCMPFDDDKSNIHKMLWQQQEHKVCFPKPHSCWISQECKDLIRHMLQPHPCNRPHINEICHHCWM
Kinase NuaK1.AA BRSK 55-306 44 1.2e-86 294.17 In-house 1-254 (254) Show / Hide 
Range on Protein: 55-306
Range on HMM: 1-254/254
Sequence Identity: 44% (112 aa)

YELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIK-DEQDMVHIRREIEIMSSLNHPHIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSER
| |  |||||. |.||  .   .|. |||| | | |    |     . ||| ||   .|||.. .|.|.|||     |.|. | |||.||  .. ||  .
YRLEKTLGKGQTGLVKLGVHCVTGKKVAIKIINKEKLSNKESMLMKVEREIAIMKLIDHPHVMKMYDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPK

ETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLDDNCNIKIADFGLSNLYQKDKFLQTFCGSPLYASPEIVNGRPYRGPEVDSWALGVLLYTLVYGTMPF
| | |||||.||. .||   . ||||| || |||.  ||||||||.  |  ||  | | |||| ||.||.. |  | |   | |  || || |  | .||
EARKFFRQIISALDFCHSHNICHRDLKPENLLLDEKNNIKIADFGMASLQVKDMMLHTSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALPF

DGFDHKNLIRQISSGEYREPTQ-PSDARGLIRWMLMVNPDRRATIEDIANHWWV
|     .|   .  | .  |   . |.  | | |. |.||.| ....|  | |.
DDDNLRQLLEKVKRGVFHMPHFIHPDCQDLLRGMIEVDPDKRISLKEIQKHPWY
Kinase NuaK1.AA MELK 55-306 42 2.5e-84 286.44 In-house 1-254 (254) Show / Hide 
Range on Protein: 55-306
Range on HMM: 1-254/254
Sequence Identity: 42% (110 aa)

YELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHPHIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERE
||. ...| | ..||| |.  . .. |||| . |...   .|.  .. |.. . .| | ||  .| . | .||| ..||| . ||..||| .. ||.| |
YEVHDEIGTGGFAKVKLACHILTNQMVAIKIMDKNQL--GHDLPRVKTEMDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEEE

TRHFFRQIVSAVHYCHKNGVVHRDLKLENILLDDNCNIKIADFGLSNLY--QKDKF-LQTFCGSPLYASPEIVNGRPYRGPEVDSWALGVLLYTLVYGTM
|||||||||||. | |  |  ||||| ||.|.|.. ..|. ||||      .||.  ||| |||| || ||...|. | | | | |..|.|||.|. | .
TRHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKTKGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGFL

PFDGFDHKNLIRQISSGEYREPTQPS-DARGLIRWMLMVNPDRRATIEDIANHWWV
|||    . . ..| || | ||   |  .. |.| || |.|..|  . .. || ||
PFDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV
Kinase NuaK1.AA Ciliate-E2 55-306 24 6.3e-84 285.13 In-house 1-365 (365) Show / Hide 
Range on Protein: 55-306
Range on HMM: 1-365/365
Sequence Identity: 24% (94 aa)

YELQETLGKGTYGKVKRATE-----------------------RFSGRVVAIKSIRKDKIKDEQDMVHIRREIE----------IMSSLNHPHIISIYEV
|.... .|.|..|.|....                         . .  .|.|...|..|.    . || |||.          |...||||.|| .||.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE--NKDKIVIIMEYASKGELYDYISERR-----------RLSERETRHFFRQIVS---------------AVHYCHKNG-VVHRDLKLENILLDDNCNI
|.  ....| ..|||.. |.|.||| ...           ...|.| .....||..               |..|.|... ..|||.|.||||.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KIADFGLS----------------NLYQKDK-----------------FLQTFCGSPLYASPEIVNGRPY--------RGPEVDSWALGVLLYTLVYGTM
||.|||||                ..|.  |                   .|.||.| | .|||.|| .|         . ..| |.|||.|| ...|  
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFDGFDHKNLIRQISSGEYREP-------------------TQPSDARGLIRW----MLMVNPDRRAT-IEDIANHWWV
||        ..||  .... |                     . ..  ||.     || ..|. | | .|.| || | 
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase NuaK1.AA Pkinase_Tyr 55-206 28 2.7e-32 110.0 Pfam 1-164 (270) Show / Hide 
Range on Protein: 55-206
Range on HMM: 1-164/270
Sequence Identity: 28% (47 aa)

YELQETLGKGTYGKVKRATER----FSGRVVAIKSIRKDKIKDEQD--MVHIRREIEIMSSL-NHPHIISIYEVFE-NKDK--IVIIMEYASKGELYDYI
 .. ..||.| .|.|...| .      .  ||.|.. |.   ....  .    ||..||..| .||.|.. | |    ..   | |.|||. .| |.|| 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

SE----RRRLSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLDDNCNIKIADFGLSNLYQKD
 .    ...|.  .  .. .|| ..  | . .. .||||   |.|...|  .||.||||. . ..|
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYND
Kinase NuaK1.AA TyrKc 55-304 24 5.5e-26 93.58 SMART 1-280 (280) Show / Hide 
Range on Protein: 55-304
Range on HMM: 1-280/280
Sequence Identity: 24% (71 aa)

YELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSL--NHPHIISIYEVFENK-------DKIVIIMEYASKGELYDYIS
 .| ..|| | .|.| ..| .   . ||.|....|.      .  ..||..||..|  .||.|. .| |   .       . . |.|||...| | ||. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

ERRR-LSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLDDNCNIKIADFGLSNLYQKD------KFLQTF----CG---SPL-YASPEIVNGRPYR
..|. |. ..  .|  || .   | |.....||||   |.|...|  .||.|||||     |      |   .     .|    |.   .||  | . . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF-

GPEVDSWALGVLLY-TLVYGTMPFDG-----FDHKNLIRQISSGEYREPTQP-----------SDARGLIRWMLMVNPDRRATIEDIANHW
 .. | |. ||...  . || .|  |      . . .|... .|..... .               . ....  . .|. | | ..|   .
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF