Gene CK2a2 (Human)

CK2a2

Species: Human
Alias: CK2a2, CK2A2, FLJ43934, CK2alpha`, CSNK2A2, CSNK2A1
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP , GeneCards
Annotation: Consensus chromosomal location: 16p12-p13.3,

Classification

Group: CMGC
Family: CK2

Sequence

Name Sequence Type Origin Length Description Download
CK2a2.NA RNA Sugen Kinome 1674 None Fasta, JSON
CK2a2.AA Protein Sugen Kinome 350 None Fasta, JSON
CK2a2.kin_dom Protein Kinase Domain Sugen Kinome 286 None Fasta, JSON

Protein domain

Protein domains of CK2a2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CK2a2.AA CK2 40-325 78 6.6e-237 716.03 In-house 1-288 (288) Show / Hide 
Range on Protein: 40-325
Range on HMM: 1-288/288
Sequence Identity: 78% (227 aa)

YQLVRKLGRGKYSEVFEAINITNNERV--VVKILKPVKKKKIKREVKILENLRGGTNIIKLIDTVKDPVSKTPALVFEYINNTDFKQLYQILTDFDIRFY
|...||.||||||||||.|||.|||..  |.||||||||||||||.||||||.||.|||||.|.||||.||.|||||||.|||||.|||| |||.|||.|
YEVIRKIGRGKYSEVFEGINIKNNEKCKIVIKILKPVKKKKIKREIKILENLNGGPNIIKLYDIVKDPYSKVPALVFEYVNNTDFRQLYQTLTDYDIRYY

MYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRREPFFHGQ
|.|||||||||||.|||||||||||.||||...|||||||||||||||.|.|||||||||.||||||||||.|||||||||||||.|||||..||||||.
MFELLKALDYCHSMGIMHRDVKPHNIMIDHEKRKLRLIDWGLAEFYHPGQDYNVRVASRYYKGPELLVDYQYYDYSLDMWSLGCMFASMIFKKEPFFHGH

DNYDQLVRIAKVLGTEELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYF
|||||||.|.||||||.|| ||.||.|.|||.|.||..||..|.||.|||.||.||..|||.|.|||.||||||.|.|||||||||||
DNYDQLVKIVKVLGTEDLYKYLDKYGIHLDPQFHDIMQQHKKKPWERFIHQENKHLAHPEAIDFLDKMLRYDHQERITAKEAMEHPYF
Kinase CK2a2.AA CMGC 40-325 21 3.9e-105 346.54 In-house 1-513 (513) Show / Hide 
Range on Protein: 40-325
Range on HMM: 1-513/513
Sequence Identity: 21% (109 aa)

YQLVRKLGRGKYSEVFEAIN--------------ITNNERVVVKILKPVKKKKIK---------------REVKILENLR----------------GGTN
|. ..|.|.| |..|.....              . .||.| .|..| .. ...                ||.|||..|.                   |
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IIKLIDTVKDPVSKTP---------------ALVFEYINNTDFKQLYQ-----------ILTDFD------------IRFYM------YELLKALD--YC
|.||.| .... |...                |||||. .. .. ...            |..              |...|      | .|..|.  ||
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HSKG--IMHRDVKPHNVMIDHQQKK-------------------LRLIDWGLAEFYHPA----------------------QEYNVRVASRYFKGPELLV
||..  |.||| || |..|.|. .                    |...|.||| .|||                       . |  .|..|. . ||.|.
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

DYQMYD---------YSLDMWSLGCMLASM-------IFRREPFFHGQDN-----------YDQLVRIAKVLG------------------TEELYGYLK
 .. |.         .. ||||.||..| |       |||..|.|.|...           .||| .| ||||                  .|| ....|
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

KYHIDLDPH----------FNDI----------LGQHSRKRWENFIHSEN------------------------------RHLVSPEALDLLDKLLRYDH
... ...|.          ...           .... .| |.|..   .                              |.. .|.|.|||.|.|.||.
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

QQRLTAKEAMEHPYF
..|.||..|..||||
DKRITAEQALQHPYF
Kinase CK2a2.AA Pkinase 40-325 27 1.3e-94 325.45 Pfam 1-293 (293) Show / Hide 
Range on Protein: 40-325
Range on HMM: 1-293/293
Sequence Identity: 27% (86 aa)

YQLVRKLGRGKYSEVFEAINITNNERVVVKILKPVKKKKIKR-------EVKILENLRGGTNIIKLIDTVKDPVSKTPALVFEYINNT----DFK-----
|...||.|.| ...|...... ....|.|||.| ...|. |.       |..|. .| .  ||..|.|.. |  .. . .|.|| ...    | .     
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST

QLYQIL--TDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKK---LRLIDWGLAEF--YHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDM
. .  .  .. ...||||..|..|.||||.||.|||.|| |..||..      ....|.|||..  | . . ..... ....  ||.. ..|.|... ||
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSLGCMLASMIFRREPFFHGQ----DNYDQLVRIAKVLGTEELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQ
||.||.|. |...| ||  |.    . .||...|....|..  . . ... | ... |..            | |... |..|.|..|.....|..| ..
WSCGCILYEMLCGRPPFP-GHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H--------F-HWTF-HNWSEECKDFIKWCLCKDPKK

RLTAKEAMEHPYF
|.||.....||.|
RPTAEQILQHPWF
Kinase CK2a2.AA S_TKc 40-325 26 9.2e-80 272.22 SMART 1-231 (231) Show / Hide 
Range on Protein: 40-325
Range on HMM: 1-231/231
Sequence Identity: 26% (81 aa)

YQLVRKLGRGKYSEVFEAINITNNERVVVKILKPVKKKKIKREVKILENLRGGTNIIKLIDTVKDPVSKTPALVFEYINN--TDFKQLYQI---------
|...||.|.| ...|. ....  ...| .||.|    ..|.||..||..  .  ||.||.|.  |   .   .|.||...   | ... .          
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDY-SLDMWSLGCMLASMI
..  ..|||||....||.||||.||.|||.|| |...|.    . ..| ||| ..      .  . ....  ||.|     |.. . |.||.||.|. |.
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEML

FRREPFFHGQDNYDQLVRIAKVLGTEELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAME------
 .. ||        |. .. |..|                                           ||||.|...|.|..| ..|.|| ||..      
CGYPPFP-------QMQMMFKKIG-------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIK

-HPYF
 ||.|
CHPWF
Kinase CK2a2.AA CDK 40-325 27 4.8e-61 193.97 In-house 1-284 (284) Show / Hide 
Range on Protein: 40-325
Range on HMM: 1-284/284
Sequence Identity: 27% (91 aa)

YQLVRKLGRGKYSEVFEAINITNN-----ERVVVKILK-PV-----KKKKIK----REVKILENLRGGTNIIKLIDTVKDP-VS--------KTPALVFE
|. . |.|.| | .|. |..  ..     . |  | ..        .|  .     ||...| .|    ||.||.| . .   .        ..  .|||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFE

YINNTDFKQLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQK----KLRLIDWGLAEFYH-------PAQEYNVRVASRYFKGPELL
|.  .| |..        |. ||. ||..|.||||..||||| || | .|... .    .| . | |||  ..       | ..|  .|  .    ||||
YM-DHDLKKYMD------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPELL

VDYQMYD--YSLDMWSLGCMLASMIF--RREPFFHGQDNYDQLVRIAKVLGT--EELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEA
   . |.   . ||||.|| .| |.    |.|.|.|.   ||| .| ...||  |.    ..|.                                    
LGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY---------------------------------

LDLLDKLLRYDHQQRLTAKEAMEHPYF
 |||.|.| || ..|..|..|..||||
-DLLNKMLCYDPKKRISAEQALQHPYF
Kinase CK2a2.AA CAMK 45-233 18 5.1e-51 162.24 In-house 1-334 (425) Show / Hide 
Range on Protein: 45-233
Range on HMM: 1-334/425
Sequence Identity: 18% (63 aa)

KLGRGKYSEVFEAINITNN------------ERVVVKILK-------------------------------PVKKKKIKREVKILENLRG------GTNI
.|||| ...|...|.. ..            ..| .||..                               |...|...||..|. .|.|        ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKLIDTVKDPVS--------KTPA----------LVF---EYINNT----D-FKQLYQI-----------------LTDFDIRFYMYELLKALDYCHSKG
|||...  ||                        .|.   ||. .     | |  . .                  .|  . |.|.  .. |..||||..
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IMHRDVKPHNVMIDHQQ----------------KKLRLIDWGLAEFYHP------------------------AQEYNVRVASRYFKG-PELLVDYQM--
|.||| || |...|.                   .. .||.|.| .. |                         | .. .. . ..   ||.|   ..  
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

-----------YDYSLDMWSLGCMLASMIFRREPF
           |... ||||.|..|  |   . ||
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPF
Kinase CK2a2.AA Ciliate-E2 40-325 17 1.4e-49 168.37 In-house 1-365 (365) Show / Hide 
Range on Protein: 40-325
Range on HMM: 1-365/365
Sequence Identity: 17% (73 aa)

YQLVRKLGRGKYSEVFEAINITNNER-----------------------VVVKILKPVKKKKIKREVKILENLRGGT----------------NIIKLID
| ...|.|.| .. |... .. ....                       . .||.|. ... ||.| .|.  ..                   ||||...
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINC-FYKKINEKNILEQLNHPNIIKMYE

TVKDPVSKTPALVFEYINNTDFKQLYQIL--------------TDFDIRFYMYELLK---------------ALDYCHSKG-IMHRDVKPHNVMIDHQQK
. ..   ..  ||.||..  | ... ..               |.. |...|...|.               || |.|||. |.||| || |...     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

KLRLIDWGLAEFYHPAQE--------------------------------YNVRVASRYFKGPELLV--DYQM------YDYSLDMWSLGCMLASMIFRR
 . .||.||. .|.. ..                                .|  . . ... || |   .|.       |||. |.||||..|  |.| .
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

EPFFHGQDNYDQLVRIAKVLGTEELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHL-----------------VSPEALDLLDK----LLRYD
 ||                                              .  ..   . .                    .|.|. ||. |    .| .|
PPF---------------------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKD

HQQRLT-AKEAMEHPYF
 ..|.| ......||.|
PEKRITGWEQILNHPWF
Kinase CK2a2.AA CDC2 40-325 29 7.2e-48 144.89 In-house 1-301 (301) Show / Hide 
Range on Protein: 40-325
Range on HMM: 1-301/301
Sequence Identity: 29% (92 aa)

YQLVRKLGRGKYSEVFEAINITNNERVVVKILKPVKKKKIK--------REVKILENLRGGTNIIKLIDTVKDPVSKTPALVFEYINNTDFKQLYQ----
|| ..|.| | | .|. ...   |. |..|  . ..             ||  .| .|.   ||.|| | ..    .   .||||. . | |..      
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIR-LEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ---NKLYMVFEYL-DMDLKKYMDMSIP

I---LTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLA-EFYHPAQEYN--VRVASRYFKGPELLVDYQMYDYSLDMWSLGC
    ..   .. ||| .|.....||...||||| || |  || . . ... | |||  |  |  .|     |  .    ||.|   . |. . ||||.||
KNKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGN-IKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGC

MLASM-IF-RREPFFHGQDNYDQLVRIAKVLGT--EELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHS--ENRHL--VSPEALDLLDKLLRYDHQQR
 .| | .   ..|.|||.   ||| .| ..|||  |. .  ....     |...   ..  ..  .. . .  .....  . ||..|||...|.|| |.|
IFAEMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQL-----PDYKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKR

LTAKEAMEHPYF
..||||..||||
ISAKEALQHPYF
Kinase CK2a2.AA Ciliate-E2-Unclassified 40-325 18 4.4e-44 150.81 In-house 1-352 (352) Show / Hide 
Range on Protein: 40-325
Range on HMM: 1-352/352
Sequence Identity: 18% (68 aa)

YQLVRKLGRGKYSEVFEAINITNNERVVVKILKPVKKKKIKREV----------KILENLR------------------GGTNIIKLIDTVKDPVSKTPA
| .....|.| ...|...... ..  . ..  . ..... .. .          |...|.                      .|.|.... .|   ... 
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQD--KQNIY

LVFEYINNTDFKQLYQI--------------------LTDFDIR-----FYMYELLKALDYCHSKG-IMHRDVKPHNVMIDHQQK--KLRLIDWGLAEFY
.| ||... | .|  ..                    .|.. ..     ||....|..|.|.|.|. | ||| || |...| ..|  ....||.|.. .|
IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKY

H----------------PAQEYNVRVASRYFK----GPELLVDYQMYD----YSLDMWSLGCMLASMIFRREPFFHGQDNYDQLVRIAKVLGTEELYGYL
                 . |... .. . ...     ||.| . | ||    |. |.||||. |  |.| . ||.  ... .| . .... .        
QQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVL-QGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWI-N--------

KKYHIDLDPHFN----DILGQHSRKRWENFIHSENR--HLVSPEALDLLD----KLLRYDHQQRLTAKEAMEHPYF
           |     .. .   | .... ...    . .|||| |..     |.| ..  .|.|......||.|
-----------NAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase CK2a2.AA ERK7 40-325 27 4.7e-40 134.49 In-house 1-292 (292) Show / Hide 
Range on Protein: 40-325
Range on HMM: 1-292/292
Sequence Identity: 27% (84 aa)

YQLVRKLGRGKYSEVFEAINITNNERVVVKIL-----KPVKKKKIKREVKILENLRGGTNIIKLIDTVKDPVSKTPALVFEYINNTDFKQLYQ---ILTD
|.. ..||.| |  |  |.     . | .|        ..   .  ||. .| ....  |||.||. ..    .   ||||.  .||     .   || |
YEIRKRLGKGAYGIVWKAYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVIRADNDRDIYLVFEFM-ETDLHAVIRKGNILKD

FDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEYNVR-------VASRYFKGPELLVDYQMYDYSLDMWSLGCMLA
   .. || ||.|. | ||  ..|||.|| |...| .   ... | |||      .||.         || | .  || |.  . |    ||||.|| |.
IHKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSEC-MVKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGCILG

SMIFRREPFFHGQDNYDQLVRIAKVLGTEELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPY
 |.  . | | |    .|. .| ....    .  ..    ..     . ..|. ||  .... .      ...|.||| .|| .  ..||||..|..|||
EMLRGK-PMFPGTSTMNQIEKILETIPKPT-QEDIEAIGSHYAWNMLEQMNQQKRKTLDQMMPQ-----CCDDAIDLLKRLLVFNPKKRLTAEQALQHPY

F
 
V
Kinase CK2a2.AA RCK 40-252 30 5.9e-35 108.13 In-house 1-232 (298) Show / Hide 
Range on Protein: 40-252
Range on HMM: 1-232/298
Sequence Identity: 30% (73 aa)

YQLVRKLGRGKYSEVFEAINITNNERVVVKILKPVKKKKIK-----REVKILENLRGGTNIIKLIDTVKDPVSKTPALVFEYINNTDFKQLYQI------
||....||.| |..|..|.|....| |  | .|  | ....     ||.| |  |    |||||.. ..|  . . ..||||   ..  |...       
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKKMK-QKFYSWEECMNLREIKSLRKLNPHPNIIKLKEVIRDNDTYQLYFVFEYM-DMNLYQMMKDFKERRK

-LTDFD--IRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQ--------QKKLRLIDWGLA-EFY--HPAQEYNVRVASRYFKGPELLVDYQMYDYSL
 |. .   |...|| .|..|...|..|..|||.|| | |.  .        |  . ..| ||. |..  .|  .|   | .|.   ||.|   . |.. .
YLPENQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIRSKPPYTDY---VSTRWYRAPECLLRCTYYNSPM

DMWSLGCMLASMIFRREPFFHGQDNYDQLVRIAKVLGT
|.|..||  .     | | | |..  ||.  | ||.||
DIWAVGCIMYELYMLR-PLFPGSSEIDQIFKICKVMGT
Kinase CK2a2.AA CDK5 40-252 34 1.9e-33 102.67 In-house 1-218 (287) Show / Hide 
Range on Protein: 40-252
Range on HMM: 1-218/287
Sequence Identity: 34% (76 aa)

YQLVRKLGRGKYSEVFEAINITNNERVVVKILKPVKK-----KKIKREVKILENLRGGTNIIKLIDTVKDPVSKTPALVFEYINNTDFKQLYQILTDFD-
|. . |.| | |  |. | | .  | |  |  .             ||. .|  |.   ||. |.| .     |   ||||.. .   | . ..  . | 
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELK-HKNIVRLHDVIH--SEKKLTLVFEFCDQDLKKYMDSCNGEMDM

--IRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAE-FYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRR
  |. .|| ||| | .||.. ..||| || | .|  .. .|.| | |||  |  | . |   |    .  |  |   ..|  | |||| || .| |.   
HIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLIN-KNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAG

EPFFHGQDNYDQLVRIAKVLGT
 | | | |  ||| || |..||
RPLFPGNDVEDQLKRIFKIMGT
Kinase CK2a2.AA CDK5 299-325 51 7.4e-13 36.47 In-house 261-287 (287) Show / Hide 
Range on Protein: 299-325
Range on HMM: 261-287/287
Sequence Identity: 51% (14 aa)

LDLLDKLLRYDHQQRLTAKEAMEHPYF
.||| |.|... .||..||.|..||||
MDLLQKMLQCNPNQRISAKAALHHPYF
Kinase CK2a2.AA CAMK 294-325 37 1.9e-12 35.71 In-house 394-425 (425) Show / Hide 
Range on Protein: 294-325
Range on HMM: 394-425/425
Sequence Identity: 37% (12 aa)

VSPEALDLLDKLLRYDHQQRLTAKEAMEHPYF
||.|. ||. |.|..| ..|.|......|| .
VSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase CK2a2.AA RCK 295-325 45 3.6e-12 34.64 In-house 268-298 (298) Show / Hide 
Range on Protein: 295-325
Range on HMM: 268-298/298
Sequence Identity: 45% (14 aa)

SPEALDLLDKLLRYDHQQRLTAKEAMEHPYF
|.....|. |.|..| | | ||..| .||||
SQDCIELMEKMLQWDPQKRITAQQALQHPYF
Kinase CK2a2.AA TyrKc 40-325 19 2.8e-09 -72.51 SMART 1-280 (280) Show / Hide 
Range on Protein: 40-325
Range on HMM: 1-280/280
Sequence Identity: 19% (62 aa)

YQLVRKLGRGKYSEVFEAINITNNERVVVKILKPVKKKKIKREVKILENL-RGGTNIIKLIDTVKDP-----VSKTPALVFEYINNTDFKQL--YQI--L
 .| .|||.| . ||.... .   . | || ||. ... . || .|. .|     ||..|.  . ..      .. . .|.||  . | |.   .    |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKL

TDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPA-------QEYNVRV--ASR-----YFKGPELLVDYQMYDYSLD
.  |   ...   .  .| |||.. |||    |.......   .  | ||. . .         . | ..    ..         || . .| ..    |
CMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFTTKSD

MWSLGCMLASMIFRREPFFHGQDNYDQLVRIAKVLGTEELYGYLKKYHIDLDPHF----NDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQ
 || | ..       | |  ||  |   .    ..  .|.. |.|. .    |.                   |         ..|  ..  .  ..|  
VWSFGVCM------WEIFTYGQQPYPGMIQQ--MMSNQEVIEYVKQGYRMPQPPNDYPMS-------------F------VCCPDEMYQIMKQCWHEDPE

QRLTAKEAMEHPYF
.| | .|   | .|
DRPTFSEI--HECF
Kinase CK2a2.AA APH 140-188 26 0.000433 14.83 Pfam 162-210 (248) Show / Hide 
Range on Protein: 140-188
Range on HMM: 162-210/248
Sequence Identity: 26% (14 aa)

ELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLR---LIDWGLAEFYHPAQE
.|.....     ...|.|..|.|||.|  . . |   .|||. | . .|...
WLEAHWP---PPCWCHGDFHPGNVMWDPRPDGGRVTGVIDWDDACWGDPHYD