Gene BMX (Human)

BMX

Species: Human
Alias: ETK, BMX, PSCTK2, PSCTK3
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP , GeneCards
Annotation: Consensus chromosomal location: Xp22.22-p22.3,

Classification

Group: TK
Family: Tec

Sequence

Name Sequence Type Origin Length Description Download
BMX.NA RNA Sugen Kinome 2598 None Fasta, JSON
BMX.AA Protein Sugen Kinome 675 None Fasta, JSON
BMX.kin_dom Protein Kinase Domain Sugen Kinome 252 None Fasta, JSON

Protein domain

Protein domains of BMX.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
BTK BMX.AA BTK 113-149 51 1.5e-22 82.18 SMART 1-37 (37) Show / Hide 
Range on Protein: 113-149
Range on HMM: 1-37/37
Sequence Identity: 51% (19 aa)

NPHLLVKYHSGFFVDGKFLCCQQSCKAAPGCTLWEAY
|.|...|||..|..||..|||||.||.||||......
NNHRMQKYHPCFWMDGHWLCCQQTCKNAPGCCPCHPH
PH BMX.AA PH 5-111 28 7.3e-21 77.87 Pfam 1-92 (92) Show / Hide 
Range on Protein: 5-111
Range on HMM: 1-92/92
Sequence Identity: 28% (31 aa)

SILEELLLKRSQQKKKMSPNNYKERLFVLTKTNLSYYEYDKMKRGSRKGSIEIKKIRCVEKVNLEEQTPVERQYPFQIVYKDG-LLYVYASNEESRSQWL
 |.|  |.|..      .  ..|.| |||. ..|.||. ||    . |||| ........ ..       .|.. |||.. |.  .|..|..||.. .|.
VIKEGWLHKKG------KRKSWKKRWFVLFNNCLYYYKDDK---YRPKGSIPLSDCQVTKVPDN------KRPHCFQIRT-DRRTYYFQAESEEEMNDWM

KALQKEIR
.|.|. .|
QAIQSACR
PH BMX.AA PH 5-113 27 7.1e-19 69.95 SMART 1-82 (82) Show / Hide 
Range on Protein: 5-113
Range on HMM: 1-82/82
Sequence Identity: 27% (30 aa)

SILEELLLKRSQQKKKMSPNNYKERLFVLTKTNLSYYEYDKMKRGSRKGSIEIKKIRCVEKVNLEEQTPVERQYPFQIVYKDGLLYVYASNEESRSQWLK
 |.|  |.|.|         ..|.| |||.   |.||. .     . |||| .......| .             |.|.. |. .|.....||.. .|..
VIKEGWLYKKS-------K-RWKKRWFVLFNDCLYYYKDK-----KPKGSIPLSDCTVRE-P------------CFEIHH-DRTYYFQCESEEEMQEWMQ

ALQKEIRGN
|.|| |. |
AIQKAIHNN
BTK BMX.AA BTK 118-149 40 1.7e-13 55.95 Pfam 1-32 (32) Show / Hide 
Range on Protein: 118-149
Range on HMM: 1-32/32
Sequence Identity: 40% (13 aa)

VKYHSGFFVDGKFLCCQQSCKAAPGCTLWEAY
 ||| .|...|...||.|..| ||||......
QKYHPCFWMNGHWSCCHQTDKNAPGCQPCHHW
SH2 BMX.AA SH2 296-377 29 4.2e-33 99.01 Pfam 1-81 (81) Show / Hide 
Range on Protein: 296-377
Range on HMM: 1-81/81
Sequence Identity: 29% (25 aa)

WFAGNISRSQSEQLLRQ-KGKEGAFMVRNSS-QVGMYTVSLFSKAVNDKKGTVKHYHVHTNAENKLYLAENYCFDSIPKLIHYH
|. |.|||.. |.||..  ...|.|.|| |. . | ||.|.. .        ||||....... ..|.... .|.|.. |....
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGP---GDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
SH2 BMX.AA SH2 294-383 37 8.5e-33 116.19 SMART 1-87 (87) Show / Hide 
Range on Protein: 294-383
Range on HMM: 1-87/87
Sequence Identity: 37% (35 aa)

YDWFAGNISRSQSEQLLRQK-GKEGAFMVRNSSQ-VGMYTVSLFSKAVNDKKGTVKHYHVHTNAENKLYLAE--NYCFDSIPKLIHYHQHNSAG
. |. |||||.. ||||..  ...|.|.|| |..  | |..|...|      | ||||....|...| |..|  ...|.|.  |....|||. |
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWK------GKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
Kinase BMX.AA Tec 417-668 74 2.6e-212 711.61 In-house 1-254 (254) Show / Hide 
Range on Protein: 417-668
Range on HMM: 1-254/254
Sequence Identity: 74% (188 aa)

ITLLKELGSGQFGVVQLGKWKGQYDVAVKMIKEGSMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKEYPIYIVTEYISNGCLLNYLRSHGKGLEPSQ--LL
.|..|||||||||||.||||..|||||.||||||||||..|..||..||||||||||..|||||...||||||||...||||||||.|..... ..  ||
LTFMKELGSGQFGVVHLGKWRHQYDVAIKMIKEGSMSEEDFIEEAKVMMKLSHPKLVQLYGVCSQQRPIYIVTEYMEHGCLLNYLREHKHHFQKNMAILL

EMCYDVCEGMAFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTRYVLDDQYVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYD
|||.|||||||.||.|.|||||||||||||... .|||||||||||||||||.|||||||||||..||||||..|||||||||||.|||||||.||.||.
EMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMTRYVLDDQYTSSVGTKFPVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKMPYE

LYDNSQVVLKVSQGHRLYRPHLASDTIYQIMYSCWHELPEKRPTFQQLLSSIEP
 ..||.|| .||||||||||||.|..||||||.|||| ||.||||||||..|..
NMSNSEVVEHVSQGHRLYRPHLCSMHIYQIMYHCWHEKPEERPTFQQLLRQITE
Kinase BMX.AA Pkinase_Tyr 417-666 45 1.2e-150 510.77 Pfam 1-270 (270) Show / Hide 
Range on Protein: 417-666
Range on HMM: 1-270/270
Sequence Identity: 45% (123 aa)

ITLLKELGSGQFGVVQLGKWK-----GQYDVAVKMIKEGSMSE----DEFFQEAQTMMKL-SHPKLVKFYGVCS-KEYP--IYIVTEYISNGCLLNYLRS
||..|.||.|.||.| .|.||     ....|||||.|||.|.|    ..|..||..|..| .||..|..||||. .. |  ||||.||  .|.||.|||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

H---GKGLEPSQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTRYV-LDDQY-VSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAF
|   .. | ...||.||.....||..|||...||||||||||||.....||..|||..|..  ||.| ... |.|.|.|| |||...| |...|||||.|
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSF

GILMWEVFSLGKQP-YDLYDNSQVVLKV-SQGHRLYRPHLASDTIYQIMYSCWHELPEKRPTFQQLLSSI
|.||||.|..|.|| |   .|..|. ..  .|.|. .|....| ||..| .|||. ||.||||..... .
GVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase BMX.AA TyrKc 417-666 42 9.40000000001e-138 464.85 SMART 1-280 (280) Show / Hide 
Range on Protein: 417-666
Range on HMM: 1-280/280
Sequence Identity: 42% (120 aa)

ITLLKELGSGQFGVVQLGKWKGQYDVAVKMIKEGSMSEDEFFQEAQTMMKL--SHPKLVKFYGVCSKE-------YPIYIVTEYISNGCLLNYLRSHGKG
|||.|.||.|.||.| .|.||  ..|||||.||..  . .| .||. |.||  .|| .|..||||...        |..||.|| ..|.|..|||.|.. 
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

LEPSQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTRYVLDD-------QYVSS---VGTK--FPVKWSAPEVFHYFKYSSKSDV
| ...||..|.....||..|.|...||||||||||||.....||.||||..|.. ||       .| ..    |.|  .|..| |||.. | |...||||
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDV

WAFGILMWEVFSLGKQPYDL-----YDNSQVVLKVSQGHRLYRPHL--------ASDTIYQIMYSCWHELPEKRPTFQQLLSSI
|.||..|||.|..|.|||        .|..|. .| ||.|. .|.         ..| .|||| .|||| ||.||||... . .
WSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase BMX.AA Src 417-666 50 2.7e-122 412.61 In-house 1-255 (255) Show / Hide 
Range on Protein: 417-666
Range on HMM: 1-255/255
Sequence Identity: 50% (128 aa)

ITLLKELGSGQFGVVQLGKWKGQYDVAVKMIKEGSMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKEYPIYIVTEYISNGCLLNYLR--SHGKGLEPSQLL
|.|...||.|||| |  |.|.|. .|||| .|.|.|| . | ||||.| ||.|.|||. | |||.| |||||||| |.|.|| ||.  . |. |.  ||.
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGTMSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQLI

EMCYDVCEGMAFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTRYVL--DDQYVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQP
.|   | ||||.||| ..||||||||| ||. ....|| |||  | .   || |... | |||.|| ||| ..| ... ||||| ||||..|... |. |
DMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVP

YDLYDNSQVVLKVSQGHRLYRPHLASDTIYQ-IMYSCWHELPEKRPTFQQLLSSI
|   .| .|. .|..| |. .||   | .|. ||  |||. ||.||||  | .  
YPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase BMX.AA TK 417-666 24 3.2e-120 404.97 In-house 1-486 (486) Show / Hide 
Range on Protein: 417-666
Range on HMM: 1-486/486
Sequence Identity: 24% (118 aa)

ITLLKELGSGQFG---VVQLGKWKGQ--------------------------YDVAVKMIKEG-SMSEDEFFQ--------------EAQTMMKLS----
|||.|.||.||||   .| .|.|.|.                           .|||||.||| .||..|||.              ||. |....    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPKLVKFYGVCSKE------------YPIYIVTEYISNGC----LLNYLRSHGKG--------------------------------------------
 || .|..||||...             |..||.|| ..|.    |..|||.. ..                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LEPSQLLEMCYDVCEGMAFLESH------QFIHRDLAARNCLVDRDLC-----------VKVSDFGMT-
                               | . ||| ||.....||..|.|.      .|.|||||||||||....            .|..|||.. 
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-------RYV-LDDQYVSSV------------------------GTKFPVKWSAPEVFH---------YFKYSSKSDVWAFGILMWEVFSLG-KQPYDLY
       |..  || |...                         |.|.|..| |||..          | |...|||||.||.||||.|..| ...|   
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

DN---------SQVVLKVSQG--------------HRLYRPHLAS--------------DTIYQIMYSCWHELPEKRPTFQQLLSSI
.|          .|. .. .|              .|. .| ...              . .|..| .|||. ||.||||.||.. .
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase BMX.AA SFK-Src 417-670 47 5.9e-118 351.3 In-house 1-259 (259) Show / Hide 
Range on Protein: 417-670
Range on HMM: 1-259/259
Sequence Identity: 47% (122 aa)

ITLLKELGSGQFGVVQLGKWKGQYDVAVKMIKEGSMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKEYPIYIVTEYISNGCLLNYLRS-HGKGLEPSQLLE
| | | ||||||| |  |.| .. .||||  | |.||..|| |||| | || ||.|.. | ||    ||||.|| . .| || ||.. ||..|   ||  
IRLEKKLGSGQFGDVWKGRWNNTTEVAVKTLKPGAMSAEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLRMPQLVD

MCYDVCEGMAFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTRYVLDDQ--YVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPY
|  .|  |||.||   |.|||||||| ||     .|| |||| | . .|.  |    | |||.|| |||   . ..| |||||.||||| |.  .|  ||
MAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRIPY

DLYDNSQVVLKVSQ--GHRLYRPHLASDTIYQIMYSCWHELPEKRPTFQQLLSSIEPLR
.   |  |. .| .  | |.  |    |  |.||  || . |. ||||  |.  .|   
PGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTFESLKWQMEDFF
Kinase BMX.AA Src-Unclassified 417-666 41 4.2e-105 355.49 In-house 1-284 (284) Show / Hide 
Range on Protein: 417-666
Range on HMM: 1-284/284
Sequence Identity: 41% (119 aa)

ITLLKELGSGQFGVVQLGKWKGQYDVAVKMIKEG---SMSEDEFF--------QEAQTMMKLSHPKLVKFYGVCSKEYPIYIVTEYISNGCLLNYLRSHG
. ||..|| |||| | .|||.|  |||||  ..|    ||   |         ||||.| |..|..||. |.|||.| |.||.||| .|| || .||  |
VHLLRKLGRGQFGEVWYGKWRGKVDVAVKTMRPGHSETMSPEAFLHVKILNFCQEAQIMKKCRHQNLVHLYAVCSQEEPYYIITEYMINGSLLQWLREGG

KGLEPSQLL-------------EMCYDVCEGMAFLESHQFIHRDLAARNCLVDRDL-----CVKVSDFGMT--RYVLDDQYVSSVGTKFPVKWSAPEVFH
. . . |..              .   |  ||  ||| . .|||||||| |.          ||| |||    . . || |.   | .||.|| ||| | 
GQYLHIQDMSEETGRKNVLIGVDIAAQVASGMMYLESKKYVHRDLAARNVLIGHNNSNGVPVVKVCDFGLARKKLMQDDNYCMRTGAMFPWKWMAPECFI

YFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSQVVLKVSQGHRLYRP--HLASDTIYQ-IMYSCWHELPEKRPTFQQLLSSI
| . | ||||| .||| ||.. .|. ||   .|  |.  |. | |. .|  |.  | ||. ||  |||. |..||||  |    
YGNFSIKSDVWSYGILLWEIMTKGQTPYPGMHNREVLEHVERGYRMPKPTNHYCPDYIYEDIMKKCWHKDPQRRPTFDTLYHYF
Kinase BMX.AA UTK 417-666 33 7.2e-100 338.08 In-house 1-296 (296) Show / Hide 
Range on Protein: 417-666
Range on HMM: 1-296/296
Sequence Identity: 33% (98 aa)

ITLLKELGSGQFGVVQLGKWK------GQYDVAVKMIKEGSMSEDE------FFQEAQ---TMMKLS-HPKLVKFYGVCSKEYPIYIVTEYISNGCLLNY
. |...||.|.||.|......      .. |||||  ........|      |  ||.    |.... ||......|||..| |..||||| .|| |..|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LRSHGKGLE-------PSQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDRD-------LCVKVSDFG---MTRYVL---------DDQYVSSVG-TK
||.|.. ..         |.|.|..|. .||..|.|..|.|||||||||||...       . .|..|||   |.|.|          ...|. . . ..
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

FPVKWSAPEVFHYF-KYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSQVVLKVSQG--HRLYRPHLASDTIYQIMYSCWHELPEKRPTFQQLLSSI
 |..| |||.. .  ....|||||.||...||... |..||  . | ||.. |. |  .|. .|.  ....|..| .|||  |..||.|..|.. .
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase BMX.AA Fer 417-667 35 5.7e-96 325.15 In-house 1-283 (283) Show / Hide 
Range on Protein: 417-667
Range on HMM: 1-283/283
Sequence Identity: 35% (100 aa)

ITLLKELGSGQFGVVQLG---------KWKGQ--YDVAVKMIKEGSMSED---EFFQEAQTMMK-LSHPKLVKFYGVCSKEYPIYIVTEYISNGCLLNYL
.|| | ||.| || | .|         ||  .   .|.||. |. .....   ||..||. |.. ..||  |||||||. | ||.|| |....|.|..||
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

RSHGKG-LEPSQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDR-DLCVK--VSDFGMTRYVLDDQYVSSVG---TKFPVKWSAPEVFHYFKYSSKSD
.  ..  .   ....|||... ||..|.|.. ||||.||||||..  .. .|  .||||| |   |..| .. .   .| |..| |||.. .. ||.|.|
KKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTD

VWAFGILMWEVFSLGKQPYDL----YDNSQV----VLK-VSQGHRLYRPHLASDTIYQIMY-SCWHELPEKRPTFQQLLSSIE
||.||...||.|. |..||        . .|    . . .  |...  |  . ..|.|||  .||.. ||.|||....   ..
VWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase BMX.AA Frk 417-670 45 7.4e-94 318.12 In-house 1-260 (260) Show / Hide 
Range on Protein: 417-670
Range on HMM: 1-260/260
Sequence Identity: 45% (117 aa)

ITLLKELGSGQFGVVQLGKWKGQYDVAVKMIKEGSMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKEYPIYIVTEYISNGCLLNYLR---SHGKGLEPSQL
| |...||||||| |  |.|  .  |||| .| |.|  ..| .||| | || ||||.. | ||  | ||||.|| . .| |..||.    .|. ..  ||
IQLIRRLGSGQFGEVWEGLWNNTTPVAVKTLKPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQQL

LEMCYDVCEGMAFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTR-YVLDDQ--YVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGK
..|   |  |||.|||. .||||||||| ||. .. .|. |||. |  . |..  | | .| .||.|| |||  .| |.. |||||.||||. |.   |.
VDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITYGR

QPYDLYDNSQVVLKVSQGHRLYRPHLASDTIYQIMYSCWHELPEKRPTFQQLLSSIEPLR
 ||    | .|.  |..| |. .|     ..|.||  |||. |.|||||  |   .|   
MPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase BMX.AA TK-Unique 417-666 32 7.9e-93 314.71 In-house 1-294 (294) Show / Hide 
Range on Protein: 417-666
Range on HMM: 1-294/294
Sequence Identity: 32% (95 aa)

ITLLKELGSGQFGVVQLGKWKG-------QYDVAVKMIKEGSMSED--EFFQEAQTMMKLS-HPKLVKFYGVCSKEY-PIYIVTEYISNGCLLNYLRSHG
.......|.|.|| |  |. .|       |  ||||| |...  .|  .|..|.| |..|  || .|...|.| |   | .|. ||...|.|..|||. .
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

KG-------------------------LEPSQLLEMCYDVCEGMAFLES--HQFIHRDLAARNCLVDRDLCVKVSDFGMTRYVLDDQYVSSVGT--KFPV
..                         . | .|.  ..... ||..|.|  ....||||.|||.|. .|. .|..||||.|.| ... .|. ..  . |.
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

KWSAPEVFH--YFKY-SSKSDVWAFGILMWEVFSLGKQPYDLYDNSQVVLKVSQGHRLYRPHLA-SDTIYQIMYSCWHELPEKRPTFQQLLSSI
.| |||..   .  | ..|||||.||.||||.|.||..||  ....... .. .|.|. .|    |...|..|.|||.. ||.||.| |... .
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase BMX.AA SrcB 417-667 44 3.6e-92 312.11 In-house 1-251 (251) Show / Hide 
Range on Protein: 417-667
Range on HMM: 1-251/251
Sequence Identity: 44% (111 aa)

ITLLKELGSGQFGVVQLGKWKGQYDVAVKMIKEGSMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKEYPIYIVTEYISNGCLLNYLRSH-GKGLEPSQLLE
. | | ||.|||| | .| ....  |||| .|.|.|| . | .||  | .| | .||. | | .|| ||||.|||. .|||| .|..  |  |.  .|..
LKLVKKLGAGQFGEVWMGYYNNHMKVAVKTMKQGTMSPEAFLAEANVMKTLQHDRLVRLYAVVTKE-PIYIITEYMAKGCLLDFLKTDEGSKLSLPKLID

MCYDVCEGMAFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTRYVLDDQYVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDL
|   . ||||..| . .||||| | | ||   || |. |||. | . |. |    | |||.|| |||  ..  .  |||||.||||. |.   |. ||  
MSAQIAEGMAYIERMNYIHRDLRAANILVSETLCCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLMEIVTYGRIPYPG

YDNSQVVLKVSQGHRLYRPHLASDTIYQIMYSCWHELPEKRPTFQQLLSSIE
  |..|.  ...| |. ||    . .|.||  ||.| || ||||. | | ..
MTNPEVIRNLERGYRMPRPDNCPEELYNIMMMCWKERPEERPTFDYLQSVLD
Kinase BMX.AA S_TKc 417-669 26 2.2e-57 197.86 SMART 1-231 (231) Show / Hide 
Range on Protein: 417-669
Range on HMM: 1-231/231
Sequence Identity: 26% (71 aa)

ITLLKELGSGQFGVVQLGKWKG-QYDVAVKMIKEGSMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKEYPIYIVTEYISN--GCLLNYLRSHGKG-----L
 ..|...|.| ||.| ....|. .  ||.|.||      . . .| | ..|  || .||.|.|.     .|.|.||...  | |. |....|..     .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

EPSQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTRYVLDDQYVSSVGTKFPVKWSAPEVFHYFKYSS-KSDVWAFGILMWEVFS
 . .   ..| .|...... ||..|||||   | |.|.  ..|..|||. | .      . .|| .   . ||||.   .|.  |.|.|..|....| ..
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPW---YMAPEVL---GYGKCKCDWWSCGCILYEMLC

LGKQPYDLYDNSQVVLKVSQGHRLYRPHLASDTIYQIMYSCWHELPEKRPTFQQLLS------SIEPL
 |. |..   . |...|.            |.   ...  |..  ||||||  ..|       . . .
-GYPPFP---QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase BMX.AA Pkinase 417-666 23 4.3e-45 160.53 Pfam 1-293 (293) Show / Hide 
Range on Protein: 417-666
Range on HMM: 1-293/293
Sequence Identity: 23% (70 aa)

ITLLKELGSGQFGVVQLGKWKGQYD-VAVKMIKEGSMSEDEFFQ-----EAQTMMKLSHPKLVKFYGVCSKEYPIYIVTEYISNG----CLLNYLR-SHG
..... .||| ||.| ....||  . |||| ||  . ....  .     |.| | .|.||  |..|...  .  ||.|.||  .|     |  |.. . .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KGL--EPSQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDRDLCV----KVSDFGMTR---YVLDDQYVSSVGTKFPVKWSAPEVFH-YFKYSSKSDV
...  .. ..  ..| ...|.... |. .|||||   |.|.|..  .    |..|||  .   |  .  . . .|| .   . ||||   . .|..|.|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPW---YMAPEVIRGGQYYGPKVDM

WAFGILMWEVFSLGKQPYD------LYDNSQVVLKVSQGHRLYRPHLAS---------------------DTIYQIMYSCWHELPEKRPTFQQLLSS--I
|..|....|... |. |..        .. .....   | .| ..   .                     ..  .....|..  |.||||..|.| .  .
WSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF