Gene SGV1 (Bakers Yeast)
SGV1
Sequence
Protein domains of SGV1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | SGV1.AA | CDK-Unclassified | 60-366 | 46 | 1.5e-210 | 699.04 | In-house | 1-324 (324) | Show / Hide |
Range on Protein: 60-366 Range on HMM: 1-324/324 Sequence Identity: 46% (150 aa) YREDEKLGQGTFGEVYKGIHLETQRQVAMKKIIVSVEKD----------LFPITAQREITILKRLNHKNIIKLIEMVYDHSPDITNAASSNLHKSFYMIL ||...|.|.||||.|.|.|...||..||.|||.|...|. ...||.||||..|...||.||||...|.|||.....|....|||.||||.. YRMQCKYGEGTFGCVCKAIDFQTQKHVAIKKIMVNNKKGNKCKHILPLLNSKITDQREISCLQNCNHMNIIKFMDMHYDHDRCSKNPYYDNLHPSFYMVM PYMVADLSGVLHNPRINLEMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANILIDHNG-----VLKLADFGLARLYYGCPPNLKYPGGAGSGAKYTSVVV .||.......|||.|.||.||.|.|.|.|.|||..|.||.|.||||||..||.|..|. .||.||||.|..|..|||||.|...|.....|...|. EYMPYTWYNQLHNNRYNLSMCQIRNFMHQMLEGIAYLHCNKIMHRDIKPQNIMITNNNSTVSPMLKIADFGQACFYMNCPPNLNYQTPADPMQQYSTQVS TRWYRAPELVLGDKQYTTAVDIWGVGCVFAEFFEKKPILQGKTDIDQGHVIFKLLGTPTEEDWAVARYLPGAELTTTNYKPTLR--ERFGKYLSETGLDF |||||||||..|.|.|.|.||||..||..||.|..|||.||.|.|.|.|.|||.||||.|..|...||.|........||.... .||.|......... TRWYRAPELLFGSKCYDTGVDIWSFGCIYAEWFQGKPIFQGRTEIEQMHHIFKMLGTPCEDMWPDWRYMPDYCKIFFKYKQKFHWWNRFPKCKHASENNC LGQLLALDPYKRLTAMSAKHHPWF ..|.....||.|...|....|||| EFQMVMYQPYNRWKCMEILQHPWF |
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Kinase | SGV1.AA | CDK | 60-366 | 38 | 1.4e-151 | 488.35 | In-house | 1-284 (284) | Show / Hide |
Range on Protein: 60-366 Range on HMM: 1-284/284 Sequence Identity: 38% (126 aa) YREDEKLGQGTFGEVYKGIHLETQ-----RQVAMKKIIVSV-----EKDLFPITAQREITILKRLNHKNIIKLIEMVYDHSPDITNAASSNLH-KSFYMI | ||.|.||.|.|||.....|. . ||.|||.. ||. ||||| |||..|| | |.||.||.. ......| .| ... | ...||. YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNN-KDK--HENKLYMV LPYMVADLSGVLHNPRINLEMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANILIDHNGV-----LKLADFGLARLYYGCPPNLKYPGGAGSGAKYTSVV .|| ||..... ||..|.|.|.||.|.| ..||||.|..||||..||. ||.|||||||.. ... .. . .||..| FEYMDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQ-----MS-EPNRTYTHEV VTRWYRAPELVLGDKQYT--TAVDIWGVGCVFAEFFE---KKPILQGKTDIDQGHVIFKLLGTPTEEDWAVARYLPGAELTTTNYKPTLRERFGKYLSET ||.||||||| ||.|.|. |..|.|.|||.|||.| .||...|...||| . ||...|||||..| ||. VTLWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY---------------------- GLDFLGQLLALDPYKRLTAMSAKHHPWF |.| ..|..||.||..| | .||.| --DLLNKMLCYDPKKRISAEQALQHPYF |
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Kinase | SGV1.AA | CMGC | 60-366 | 26 | 8.20000000001e-123 | 405.69 | In-house | 1-513 (513) | Show / Hide |
Range on Protein: 60-366 Range on HMM: 1-513/513 Sequence Identity: 26% (135 aa) YREDEKLGQGTFGEVYKGIH--------------LETQRQVAMKKIIVS---------VEKDLFPITAQREITILKRLN-----------------HKNI | ..|.|.||.|.|||... ||...||.||| .||| |||.|.||| |||.|| |.|| YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI IKLIEMVYDHSPDITNAASSNL----HKSFYMILPYMVADLSGVLHNPR--------INLEMCD------------IKNMM------LQILEGLN--YIH .||....|.. .| ... .... ...|.. || || ....| . ..|. ||..| |||.||. |.| VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH CAK--FMHRDIKTANILIDHN--------------------GVLKLADFGLARLYYGCPPNLKYPGGA---------GSGAKYTSVVVTRWYRAPELVLG .. ..|||.| .||||.|| |.||..|||||| | . . ... . ... ||. ||||||||||. || SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG DKQYT---------TAVDIWGVGCVFAEFFEK--------KPILQGKTD-----------IDQGHVIFKLLGTPT---------------EEDWAVARYL .|.|| |..|.|.|||.||| . . ||. .|... ||| . |||.||||| ||.| | WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKL PGAEL---------------------------TTTNYKPTLR------------------------ERFGKY----------LSETGLDFLGQLLALDPY |. .. . ...... |.|. . ... ..|.| ..| .|| PWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPD KRLTAMSAKHHPWF ||.|| | ||.| KRITAEQALQHPYF |
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Kinase | SGV1.AA | Pkinase | 60-366 | 31 | 7.2e-116 | 396.04 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 60-366 Range on HMM: 1-293/293 Sequence Identity: 31% (102 aa) YREDEKLGQGTFGEVYKGIHLETQRQVAMKKIIVSVEKDLFPITAQR--EITILKRLNHKNIIKLIEMVYDHSPDITNAASSNLHKSFYMILPYMVA--- |. .|.|.|.||.|||..| |...||.|.| .. ||. ...|. | || |.|||||.||..|.....| ... ||...|. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-------------KDHIYMVMEYCEGGLY --DLSGVLH-NPRINL--EMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANILIDHNGVL----KLADFGLARLYYGCPPNLKYPGGAGSGAKYTSVVVT ||. ... . .. .. ..|..|.|||.||.|.| ...|||.| .|||||.||.. |..|||||.... .. .|....| VMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-----------Y-NNS-MTTFCGT RWYRAPELVLGDKQYTTAVDIWGVGCVFAEFFEKKPILQGK----TDIDQGHVIFKLLGTPTEEDWAVARYLPGAELTTTNYKPTLRERFGKYLSETGLD .||.|||...|.. |...||.|..||...|.. ..|. .|. . .|| ..|.. .|.|...|| . . . ... . .. ...| ...||...| PWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-HF-HWTF-HNWSEECKD FLGQLLALDPYKRLTAMSAKHHPWF |. .|..||.||.||. ...|||| FIKWCLCKDPKKRPTAEQILQHPWF |
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Kinase | SGV1.AA | CDC2 | 60-366 | 37 | 2.4e-100 | 309.1 | In-house | 1-301 (301) | Show / Hide |
Range on Protein: 60-366 Range on HMM: 1-301/301 Sequence Identity: 37% (124 aa) YREDEKLGQGTFGEVYKGIHLETQRQVAMKKIIVSVEKDL--FPITAQREITILKRLN-HKNIIKLIEMVYDHSPDITNAASSNLHKSFYMILPYMVADL | ||.| ||.|.|||.....|...||.||| . | . .| || ||| .|| |. |.||.|| . .. .. ||. |. || YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ--------------NKLYMVFEYLDMDL SGVLH---NPRINLEMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANILIDHNGVLKLADFGLARLYYGCPPNLKYPGGAGSGAKYT--SVVVTRWYRAP . .. ... .|. | |||.|... | . ||||.| ||||| .|..|.||||||| | | . .|| |||.||||| KKYMDMSIPKNKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARA-FGIPIR-----------TYTTEHEVVTLWYRAP ELVLGDKQYTTAVDIWGVGCVFAEF---FEKKPILQGKTDIDQGHVIFKLLGTPTEEDWAVARYLPGAELTTTNYKPT-LRERFGK--------YLSETG |. ||.|.|.|.||.| .||.|||. .|||. .|. ||| ||. ||||.|..| || | ..||. |.. . . | ..| EILLGCKRYSTPVDMWSIGCIFAEMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEG LDFLGQLLALDPYKRLTAMSAKHHPWF .| | |.|..||.||..| .| ||.| IDLLMQMLQYDPQKRISAKEALQHPYF |
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Kinase | SGV1.AA | PITSLRE | 60-366 | 40 | 8.1e-99 | 334.59 | In-house | 1-295 (295) | Show / Hide |
Range on Protein: 60-366 Range on HMM: 1-295/295 Sequence Identity: 40% (130 aa) YREDEKLGQGTFGEVYKGIHLETQRQVAMKKIIVS--VEKDLFPITAQREIT-ILKRLNHKNIIKLIEMVYDHSPDITNAASSNLHKSFYMILPYMVADL . . . ||.|.||.. .| . ||.|.. . ||. ||||. ||| ||. |.| ||... | | ||. | ||.. |. || FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVNVKEIV----------MGSNMDK-IYMVMEYVEHDL SGVLHNPR---INLEMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANILIDHNGVLKLADFGLARLYYGCPPNLKYPGGAGSGAKYTSVVVTRWYRAPEL ... | . || .|.| | | . | . |||| ||.|.|. |.|.||..|||||| || | .||..||| ||||||| KSLMENMKRRNQPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAR-EYGSP-----------IKPYTPCVVTLWYRAPEL VLGDKQYTTAVDIWGVGCVFAEFFEKKPILQGKTDIDQGHVIFKLLGTPTEEDWAVARYLPGAELTT--TNYKP-TLRERFG--KYLSETGLDFLGQLLA || | |.|.||.| |||.|||| .||..||| .||| . |||..||||| | ||.. ... ..|.. .||.||. ...|.||.| | |.| LLGCKKYSTPVDMWSVGCIFAEFITMKPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNNFPHYPYNNLRKRFPAENHISDTGFDLLNQMLT LDPYKRLTAMSAKHHPWF ..| .|.|| | |||| YNPKNRITASDALKHPWF |
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Kinase | SGV1.AA | CRK7 | 60-366 | 35 | 3.3e-94 | 319.29 | In-house | 1-343 (343) | Show / Hide |
Range on Protein: 60-366 Range on HMM: 1-343/343 Sequence Identity: 35% (128 aa) YREDEKLGQGTFGEVYKGIHLETQRQVAMKKIIVSVE---KDLFPITAQREITILKRLNHKNIIKLIEMVYDHSPDITNAASSNLHK-SFYMILPYMVAD |. . | ||.| ||| ..| .|| ||.. | |. ||||| ||| ||. |||.||..| | | | | .. || ||||. || | YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQLNHQNIVNLKEIVTDK----QDASEFKKHKGSFYMVFEYMDHD LSGVLHNPRIN-LEMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANILIDHNGVLKLADFGLARLYYGCPPNLKYPGGAGS-GAKYTSVVVTRWYRAPEL |.| | .. . .| .| |.|||..|.| .|.||||| .|||.. .| .|.||||||||| . . ..|| |.| |||.||| LMGLLESKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYN-----------SEEKRRPYTNRVITLWYRPPEL VLGDKQY--------------------------------------TTAVDIWGVGCVFAEFFEKKPILQGKTDIDQGHVIFKLLGTPTEEDWAVARYLPG ||...| ....|.|..|| ..| | ||||.||. ..| |.|. |.|. . | . ||. LLGEERYTEQHILKELIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNPNNWPEVMKLPW -AELTTTN-YKPTLRERFG---K--YLSETGLDFLGQLLALDPYKRLTAMSAKHHPWF . |. ||| | | ... || | ..|.||| || || . |.|| WNTMKPKRQYNRRLREEFYHHKKPVFMPKECLDLLDKMLCLDPKKRFTAEECLQHDWF |
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Kinase | SGV1.AA | S_TKc | 60-366 | 26 | 6.3e-94 | 319.27 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 60-366 Range on HMM: 1-231/231 Sequence Identity: 26% (87 aa) YREDEKLGQGTFGEVYKGIHLETQRQVAMKKIIVSVEKDLFPITAQREITILKRLNHKNIIKLIEMVYDHSPDITNAASSNLHKSFYMILPYMVA---DL |. .|.|.|.||.|||..| .|.|.||.|.| ....||| |||. .|.||.||... .| ...||.. |. || YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD--------------DHLYMVMEYCDGDLGDL SGVLHNPRIN-----LEMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANILIDHNGVLKLADFGLARLYYGCPPNLKYPGGAGSGAKYTSVVVTRWYRAP .... . . . ... .| ||...|.|.| ...|||.| .|||.|. ..|..||||||.. |....|.||.|| FDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------------------TTFCGTPWYMAP ELVLGDKQYTT-AVDIWGVGCVFAEFFEKKPILQGKTDIDQGHVIFKLLGTPTEEDWAVARYLPGAELTTTNYKPTLRERFGKYLSETGLDFLGQLLALD |.. .|.. ..|.| .||...|.. .| . | ...||..| |. ..||. ..| | EVL----GYGKCKCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG-----------------------------------SPEAKDFIRKCLQKD PYKRLTAMSAKH-------HPWF | ||.|| | . |||| PEKRPTA-EALQDEWDIKCHPWF |
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Kinase | SGV1.AA | CDK7 | 60-307 | 42 | 1.7e-89 | 238.42 | In-house | 1-227 (288) | Show / Hide |
Range on Protein: 60-307 Range on HMM: 1-227/288 Sequence Identity: 42% (106 aa) YREDEKLGQGTFGEVYKGIHLETQRQVAMKKII----VSVEKDLFPITAQREITILKRLNHKNIIKLIEMVYDHSPDITNAASSNLHKSFYMILPYMVAD | ...| |.|. |||. ..| . || ||| | || || ||| ||. . | |.| || .. ||. .... .| | YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIF---------MHKSNI----QLVFDFMDWD LSGVLHNPRINLEMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANILIDHNGVLKLADFGLARLYYGCPPNLKYPGGAGSGAKYTSVVVTRWYRAPELVL | | | | .||. |...| || | | |||.| | |.. ||.||.||||||| || | ||. ||||||||||| LEVVIKDKSIILTPAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARF-YGSPNRI-----------YTHQVVTRWYRAPELLF GDKQYTTAVDIWGVGCVFAEFFEKKPILQGKTDIDQGHVIFKLLGTPTEEDW | ..|.|.||.| |||.||| |.| | |||| .||. |||||||.| GARHYGTGVDMWSVGCIFAELMLRVPYLPGDSDIDQLTRIFQTLGTPTEEEW |
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Kinase | SGV1.AA | CDK5 | 60-366 | 36 | 6e-81 | 255.43 | In-house | 1-287 (287) | Show / Hide |
Range on Protein: 60-366 Range on HMM: 1-287/287 Sequence Identity: 36% (113 aa) YREDEKLGQGTFGEVYKGIHLETQRQVAMKKIIVSVEKDLFPITAQREITILKRLNHKNIIKLIEMVYDHSPDITNAASSNLHKSFYMILPYMVADLSGV | ||.| ||.| |||. ||. ||.|.. | | || ||| .|| | ||||. |. . || | .. .. || YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVI--HS-----------EKKLTLVFEFCDQDLKKY LHNPRINLEMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANILIDHNGVLKLADFGLARLYYGCPPNLKYPGGAGSGAKYTSVVVTRWYRAPELVLGDKQ . . ...| || .|.| | || . | . .||| | | || || |||||||||| .| | . |.. ||| |||.| .| |. MDSCNGEMDMHIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARA-FGIPVRC-----------YSHEVVTLWYRPPDVLMGSKH YTTAVDIWGVGCVFAEFF-EKKPILQGKTDIDQGHVIFKLLGTPTEEDWAVARYLPGAE---LTTTNYKPTL-RERFGKYLSETGLDFLGQLLALDPYKR |.| .|.| .||.||| .| | . || |||..|||.|. | || | .. . . |.|.|.|.|...| ..| .| YSTSIDMWSCGCIFAEMANAGRPLFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQR LTAMSAKHHPWF ..| | |||.| ISAKAALHHPYF |
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Kinase | SGV1.AA | CDK9 | 60-307 | 41 | 6.9e-78 | 265.07 | In-house | 1-250 (340) | Show / Hide |
Range on Protein: 60-307 Range on HMM: 1-250/340 Sequence Identity: 41% (109 aa) YREDEKLGQGTFG-----------EVYKGIHLETQRQVAMKKIIVSVEKDLFPITAQREITILKRLNHKNIIKLIEMVYDHSPDITNAASSNLHKS---F | | |||||| ||.| | .. | |||||. || ||||| ||| .|. | | |.. ||| | | | |. | YEKLAKIGQGTFGQVLQGRKSRNSEVFKARHKKNKRMVAMKKVLMENEKEGFPITALREIKMLQLLKHENVVNLIEIC------RTKATAYNRYKDRATF YMILPYMVADLSGVLHNPRINLEMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANILIDHNGVLKLADFGLARLYYGCPPNLKYPGGAGSGAKYTSVVVT |... . || | | |... . . .|| || . . ||.||| | .||| | ||.|| .|.|||||||||| . ..|. || ||| YLVFDFCEHDLAGLLSNMNVKFSLGHIKKMMQHLMNGLYYIHRNKILHRDMKAANVLITKDGILKLADFGLARAF------SQPKNDAPNRPLYTNRVVT RWYRAPELVLGDKQYTTAVDIWGVGCVFAEFFEKKPILQGKTDIDQGHVIFKLLGTPTEEDW ||| ||| ||| .| ...|.|| ||. || ||.|| | | | .| | |.. | LWYRPPELLLGDRNYGPPIDMWGAGCIMAEMWTRSPIMQGNTEQHQLQLISQLCGSITPDVW |
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Kinase | SGV1.AA | MAPK | 60-366 | 31 | 3.2e-71 | 242.91 | In-house | 1-328 (328) | Show / Hide |
Range on Protein: 60-366 Range on HMM: 1-328/328 Sequence Identity: 31% (107 aa) YREDEKLGQGTFGEVYKGIHLE------TQRQVAMKKIIVSVEKDLFPITAQREITILKRL-NHKNIIKLIEMVYDHSPDITNAASSNLH--KSFYMILP |. ....||| .| | . |. . ....|| ||| .. .. ..||| .|... .|.|||||... . . . . ..|. . .|.. . YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEM---Q-DDQNSLEEFNDIYIVME YMVADLSGVLHNPRINLEMCDIKNMMLQILEG--LNYIHCAKFMHRDIKTANILIDHNGVLKLADFGLARLYYGCPPNLKYPGGAGSGAKY------TSV .| .|| ... .. |. |. | ||| | | ||| | |||.| .|||.. |. ||..|||||| .. |. ..... . | LMETDLHQIIKSQQ-PLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLAR---SIDPEYHHHHQQDDP-HCFQKMHMTEY VVTRWYRAPELVLGD--KQYTTAVDIWGVGCVFAEFFE-KKPILQGKTDIDQGHVIFKLLGTPTEEDWAVAR-Y-LPGAELTT----TNYKP-TLRERFG |.||||||||. |. . ||.|||.| ||| |||. ||...|| ||| |...||||.||.. . . . ..|.. .... | VATRWYRAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFP K---YLSETGLDFLGQLLALDPYKRLTAMSAKHHPWF . . .|.| ..|..|| ||.|. | || | NANFNANPQAIDLLEKMLVFDPDKRITVEEALQHPYF |
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Kinase | SGV1.AA | Pkinase_Tyr | 60-221 | 30 | 4.5e-25 | 85.53 | Pfam | 1-162 (270) | Show / Hide |
Range on Protein: 60-221 Range on HMM: 1-162/270 Sequence Identity: 30% (55 aa) YREDEKLGQGTFGEVYKGIHL----ETQRQVAMKKI--IVSVE---KDLFPITAQREITILKRL-NHKNIIKLIEMVYDHSPDITNAASSNLHKS--FYM . ..|||.| |||||||. .|. .|| |.. . | .. | ||. |.| | .|.||..|. .. .. |. ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDF----MREAKIMKQLGHHPNIVRLYGVCT------------DQGEPNQIYI ILPYMVA-DLSGVLHNP---RINLEMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANILIDHNGVLKLADFGLARLYY ...|| || |... . .| | |. .| .|| .|..| . .. |||. . |.|...|.| | .||||||. | VMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIY |
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Kinase | SGV1.AA | TyrKc | 60-331 | 23 | 5.2e-14 | 3.8 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 60-331 Range on HMM: 1-280/280 Sequence Identity: 23% (72 aa) YREDEKLGQGTFGEVYKGIHLETQRQVAMKKIIVSVEKDLFPITAQREITILKRL--NHKNIIKLIEMVYDHSPDITNAASSNLH---KSFYMILPYMVA . ..||| | |||||||. .||| |.. . . | ||. |...| .|.||..|. . ... . .... || ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDF----MREARIMCKLGGHHPNIVRLYGVCTQQGRN---------FMYIEPLMIVMEYMPH -DLSGVLHNPRINLEMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANILIDHNGVLKLADFGLARLYYGC----PPNLKYPGGAGSGAKYTSVVVTRWYR || |...| .| | | ....|| .| .|.| .. |||. . |.|...|.. | .||||.| | | ..|.|. .. ||. GDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKT--MLPIRWM- APELVLGDKQYTTAVDIW--GVGCVF------AEFFEK-----KPILQGKTDIDQGHVIFKLLG-------TPTEEDWAVARY---------LPGAELTT ||| .. .. .||. |.| || | . .. . .. . ...||. . . ..| . . .|. APE-CINYGKFTTKSDVWSFGV-CMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-- TNYKPTLRERF .|.| -------HECF |
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Kinase | SGV1.AA | CDK9 | 337-366 | 33 | 2.7e-08 | 24.42 | In-house | 311-340 (340) | Show / Hide |
Range on Protein: 337-366 Range on HMM: 311-340/340 Sequence Identity: 33% (10 aa) ETGLDFLGQLLALDPYKRLTAMSAKHHPWF ..... . ||..|| ||... | | || QQACHLIDKLLNIDPKKRMDSDEALDHDWF |
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Kinase | SGV1.AA | CDK7 | 336-366 | 29 | 7.1e-08 | 16.59 | In-house | 258-288 (288) | Show / Hide |
Range on Protein: 336-366 Range on HMM: 258-288/288 Sequence Identity: 29% (9 aa) SETGLDFLGQLLALDPYKRLTAMSAKHHPWF |. ||.. .....| ||.|. . .| | SDDLLDLMCGMWTMNPCKRWTCTQCLKMPYF |