Gene prk-1 (Nematode worm)
prk-1
Sequence
Protein domains of prk-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | prk-1.AA | PIM | 34-286 | 52 | 5.5e-192 | 644.09 | In-house | 1-260 (260) | Show / Hide |
Range on Protein: 34-286 Range on HMM: 1-260/260 Sequence Identity: 52% (136 aa) YEVLDEIGRGGFGIVYEATTRQDGQQPVAVKFVQHKHVRSWTMTC-RQLIPSEVCHLETCEDI---PGVIKILDWFANSKGFLIVMERPANCMDLFDMVS |.|..|.||||||.||......|.|||||.|.|....|..|.|.| .|..|.|||.|..|..| .|||..||||....||.||||||..|.||||... YQVGPELGRGGFGTVYAGHRICDNQQPVAIKHVEKERVKDWGMLCDGQQVPMEVCMLWKCSSIGGHHGVIRLLDWFERPDGFMIVMERPYPCQDLFDFIT VHGPLNEDMGKFIFKQVITTVFNMYSKHGLLHRDIKDENLIVNMNTGEVKLVDFGATAYAEKATKKEFQGTRSYCPPEWFRDQLYLPLEATSWSLGVLLF ..|||||||..|.|.||..||......| .|||||||||....||||||||.||||.|.........|.|||.||||||.|...|...|||.|||||||. EQGPLNEDMCRFFFWQVWATVHHCHQCH-VLHRDIKDENILIDMNTGEVKLIDFGAGAMLHDTVYTDFDGTRVYCPPEWIRHHRYHGREATVWSLGVLLY ILLTGKLPFRNEIQIC----LGNVKFPPDLSKEVCQLVKSCLTTSTSARASLAQIAAHPWM ....|..||.|...|| ||...|....|.|.|||...|||...|.|.||.||..|||| DMVCGDIPFENDQEICRAHLLGELHFRQHVSHECCQLIRWCLTFKPSHRCSLEQILNHPWM |
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Kinase | prk-1.AA | CAMK | 39-286 | 18 | 6.8e-75 | 240.58 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 39-286 Range on HMM: 1-425/425 Sequence Identity: 18% (77 aa) EIGRGGFGIVYEATTRQDGQ-----------QPVAVKFVQ----------------------HKHVRSW-TMTCRQLIPSEVCHLETCE------DIPGV ..|||.||.|.... ..... | ||.|.. || ..| . |. ...|.. . .. | | . TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI IKILDWFA------------NSKG--------FLIVM---ERPANC---MDLFDMVSVHGP---------------LNEDMGKFIFKQVITTVFNMYSKH ||..... . . . .|| | . .||||.. ||. ..|. ...|.|.. | . |.. IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN GLLHRDIKDENLIVN----------------MNTGEVKLVDFGATAYAEKA-------------------------TKKEFQGTRSYCP-PEWFRD---- |||.| ||. .. .|.. .|..||| .. .. |.| || .|.. ||... -IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC ---------QLYLPLEATSWSLGVLLFILLTGKLPFRNE-------------------IQICLGNVKFPPD------------------------LSKEV . | . .. ||.||.|.|.|.|..||. . .|. |. |||. .|.|. NMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQEC CQLVKSCLTTSTSARASLAQIAAHPWM .|....|.. . |....|. .|||| KDLIRKMLQVDPEKRMTIEQCLNHPWM |
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Kinase | prk-1.AA | S_TKc | 34-286 | 25 | 1.2e-53 | 185.49 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 34-286 Range on HMM: 1-231/231 Sequence Identity: 25% (67 aa) YEVLDEIGRGGFGIVYEATTRQDGQQPVAVKFVQHKHVRSWTMTCRQLIPSEVCHLETCEDIPGVIKILDWFANSKGFLIVMERPANC-MDLFDMVSVHG ||.|..||.|.|| || .. . .. ||.| . . | .|. |. . | ..|..|.| . . . .||| .. ||||. .| YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK------------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRG P------LNEDMGKFIFKQVITTVFNMYSKHGLLHRDIKDENLIVNMNTGEVKLVDFGATAYAEKATKKEFQGTRSYCPPEWFRDQLYLPLEATSWSLGV . ..| . .|...|.. . . |. | .|||.| ||. .. ..|. ||| . . | ||. |..|| . | . .. ||.|. RHGLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE---HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC LLFILLTGKLPFRNEIQICLGNVKFPPDLSKEVCQLVKSCLTTSTSARASLAQIAA-------HPWM .|...|.|. ||. ..| . ... |.|...... ||. . | . .. . |||. ILYEMLCGYPPFP-QMQMMFKKIG-----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | prk-1.AA | Pkinase | 34-286 | 26 | 4.1e-52 | 184.26 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 34-286 Range on HMM: 1-293/293 Sequence Identity: 26% (80 aa) YEVLDEIGRGGFGIVYEATTRQDGQQPVAVKFVQHKHVRSWTMTCRQLIPSEVCHLETCEDIPGVIKILDWFANSKGFLIVMERPAN---CMDLFDMVS- |... ||.|.|| ||... . .|. |||| . .| .|| . .. ||.. . . . | .....||| ... .||| . .|||||..| YHIGRKIGSGSFGCVYKCHHKGTGK-IVAVKIIKKRHEKSWKDQTHRRL-SEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST -VHGPL--NEDMGKFIFKQVITTVFNMYSKHGLLHRDIKDENLIVNMNTGEV----KLVDFGATA---YAEKATKKEFQGTRSYCPPEWFRDQLYLPLEA ||.. |. ||...|.. . ..| .| .|||.| ||. .. |.|.. |. ||| . | . . | ||. |..||. |.. | . .. WRHGCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV TSWSLGVLLFILLTGKLPFRNE------------IQICLGNVKFPPDLS---------------------KEVCQLVKSCLTTSTSARASLAQIAAHPWM ||.|..|...|.|..||... .| . ..|. . . .| ....|.||. . | . .|| |||. DMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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Kinase | prk-1.AA | PASK | 34-286 | 31 | 1.9e-47 | 146.16 | In-house | 1-260 (260) | Show / Hide |
Range on Protein: 34-286 Range on HMM: 1-260/260 Sequence Identity: 31% (84 aa) YEVLDEIGRGGFGIVYEATTRQDGQQPVAVKFVQHKHVRSWTM-TCRQL--IPSEVCHLETCE--DIPGVIKILDWFANSKGFLIVMERPANC--MDLFD | . ..|.| .| |. . ... . | |||. | . .. | . ||.|. . | . . ..|.|| | | . .||| ||||| YTSIQQMGEGAYGYVWMCIHNEC-RYIVVVKFIFKEKVCEDCWVRDRKCGCIPLEIHIMQTLNKNPHENIVKVLDFFENDDFYQLVMEKHGSGGCMDLFD MVSVHGPLNEDMGKFIFKQVITTVFNMYSKHGLLHRDIKDENLIVNMNTGEVKLVDFGATAYAEKAT-KKEFQGTRSYCPPEWFRDQLYLPLEATSWSLG .. | . | ...||.||. | . .| .|||||||| |. . . .||.||| || |. | || || || | | |.|| FIDRHPNMDEHLASYIFRQVVAAV-KYLHEQGIVHRDIKDENVIIDEH-FTIKLIDFGSAAYMERGKFFYTFCGTIEYCAPEVLMGNPYRGPEQEMWALG VLLFILLTGKLPFRNEIQICLGNVKFP--PDLSKEVCQLVKSCLTTSTSARASLAQIAAHPWM |.|..|. || | . ....|| |.|. .|.|| |. | . || ||. VTLYTLMFKENPFCNIEETLEAEIHFPNAEHVSEECMSLIKSMLNRCPEKRCTMHQIITDPWL |
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Kinase | prk-1.AA | CAMKL | 122-286 | 27 | 1.6e-37 | 117.22 | In-house | 108-297 (297) | Show / Hide |
Range on Protein: 122-286 Range on HMM: 108-297/297 Sequence Identity: 27% (54 aa) MDLFDMVSVH----GPLNEDMGKFIFKQVITTVFNMYSKHGLLHRDIKDENLIVNMNTG-EVKLVDFGATAYAE------KATKKEFQGTRSYCPPEWFR |||||.. | |.. |. ...|.|.. | . |.. ||||| ||. . | .|..||| .. . . |.| |. .|..|| | MDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHG-IVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQ D--QLYLPLEATSWSLGVLLFILLTGKLPFRNE-------------IQICLGNVKFP--PDLSKEVCQLVKSCLTTSTSARASLAQIAAHPWM . . | .. ||.||.|. ...|.|||... .| | ..| ...| .. .| .. |.. . |... || |||| GNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM |
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Kinase | prk-1.AA | MARK | 161-286 | 33 | 2.6e-31 | 99.75 | In-house | 127-262 (262) | Show / Hide |
Range on Protein: 161-286 Range on HMM: 127-262/262 Sequence Identity: 33% (45 aa) HRDIKDENLIVNMNT-GEVKLVDFG-ATAYAEKATKKEFQGTRSYCPPEWFRDQLYLPLEATSWSLGVLLFILLTGKLPFR--N----EI--QICLGNVK ||||| ||. . |. .|. ||| .. . ..| || .|..|| | . | .. |||||.|.....|..||. . |. .| |. . HRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYD FPPDLSKEVCQLVKSCLTTSTSARASLAQIAAHPWM .|. .||| .|... ||. . |... .| |||| IPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM |
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Kinase | prk-1.AA | QIK | 120-286 | 27 | 4.1e-28 | 99.71 | In-house | 101-272 (272) | Show / Hide |
Range on Protein: 120-286 Range on HMM: 101-272/272 Sequence Identity: 27% (48 aa) NCMDLFDMVSVHGPLNEDMGKFIFKQVITTVFNMYSKHGLLHRDIKDENLIVNMNTGEVKLVDFGATAYAEKAT-KKEFQGTRSYCPPEWFRDQLYLPLE | |. | | . |..|. ...|.|... | |.. |||.| ||. | ..|..||| . .. . . |. | || | . | . NSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCH-KRNIVHRDLKAENILLDNNM-NIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPK ATSWSLGVLLFILLTGKLPFRNEIQ------ICLGNVKFPPDLSKEVCQLVKSCLTTSTSARASLAQIAAHPWM . ||.||.|..| .|.||| .. . | .. |. .|.. .|.. |. . | . .|| |.|| VDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM |
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Kinase | prk-1.AA | MELK | 34-286 | 28 | 3e-27 | 89.94 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 34-286 Range on HMM: 1-254/254 Sequence Identity: 28% (75 aa) YEVLDEIGRGGFGIVYEATTRQDGQQPVAVKFVQHKHVRSWTMTCRQLIPSEVCHLETCEDIPGVIKILDWFANSKGFLIVMERPANCMDLFDMVSVHGP ||| |||| |||. | |. .|. ||.| . ... . . |. | . . .. . ...||| ..|| . . YEVHDEIGTGGFAKVKLACHILTNQM-VAIKIMDKNQLGHDLPRVK----TEMDALKNLRHQ-HICQLYHYIETEDKIFMVMEY-CPGGEMFDYIIRQDR LNEDMGKFIFKQVITTVFNMYSKHGLLHRDIKDENLIVNMNTGEVKLVDFGATAYAEKATKKEF-----QGTRSYCPPEWFRDQLYLPLEATSWSLGVLL |.|. . .|.|.. . ..|. | |||.| |||... . ..||.||| | . | | . | | || . . |. || ||.|.|| LEEEETRHFFRQIVSAIAYVHSQ-GYAHRDLKPENLLFDEDH-HLKLIDFGLCAKT-KGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILL FILLTGKLPFRNE------IQICLGNVKFPPDLSKEVCQLVKSCLTTSTSARASLAQIAAHPWM ..|. | ||| . .| | . |. || | ||.. | | |. .. |||. YVLMCGFLPFDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV |
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Kinase | prk-1.AA | NIM1 | 124-286 | 31 | 4.8e-27 | 76.51 | In-house | 87-258 (258) | Show / Hide |
Range on Protein: 124-286 Range on HMM: 87-258/258 Sequence Identity: 31% (55 aa) LFDMVSVHGPLNEDMGKFIFKQVITTVFNMYSKHGLLHRDIKDENLIVNMNTGEVKLVDFGATAYAEK-----ATKKEFQGTRSYCPPEWFRDQLYLPLE |. .. |.| | | ||.|.. | | |. . ||||| || . |. ||..||| | .. . | | | || |.|. | LYTHIHQEGKLREIHCKPIFAQIVSAVKHMHSR-NIVHRDIKAENVMYTSNN-CVKVGDFGFSCYCKMGTGANQMLNTFCGSPPYAAPELFQDEHYIGEY ATSWSLGVLLFILLTGKLPFRNE------IQICLGNVKFPPDLSKEVCQLVKSCLTTSTSARASLAQIAAHPWM | ||.||. .|| ||| | | | |. .| .|... | . . |. |. | || VDVWALGILLYFMMTGVMPFRAETVPKMKKCILKGQYQIPDYVSLPCHRLIRGMLKHIPTQRYTIDQMMNHQWM |
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Kinase | prk-1.AA | Ciliate-E2 | 96-286 | 21 | 1.9e-26 | 87.82 | In-house | 92-365 (365) | Show / Hide |
Range on Protein: 96-286 Range on HMM: 92-365/365 Sequence Identity: 21% (62 aa) PGVIKILDWFA--NSKGFLIVMERPANCMDLFDMVSVH-----------GPLNEDMGKFIFKQVIT---------------TVFNMYSKHGLLHRDIKDE | .||. ..| . . . .||| .. .|||| . ....| |.|.||.. . . ||. .||||| | PNIIKMYECFQEKDDNNIYLVMEY-CQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPE NLIVNMNTGEVKLVDFG-ATAYAEK---------ATKKEFQG------------------------TRSYCPPEWFRDQLY--------LPLEATSWSLG |... .|..||| .. | .. . .. | . | | .|| .. . | .. |||| NILF------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLG VLLFILLTGKLPFRNEIQICLGNVKFPPD------------------LSKEVCQLVKS----CLTTSTSARAS-LAQIAAHPWM |.|...|.||.|| ..||. ....||. .|.|. .| | .| . | . || |||. VILYEMLFGKPPF--QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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Kinase | prk-1.AA | Ciliate-E2-Unclassified | 98-286 | 19 | 6.6e-24 | 79.82 | In-house | 83-352 (352) | Show / Hide |
Range on Protein: 98-286 Range on HMM: 83-352/352 Sequence Identity: 19% (54 aa) VIKILDWFANSKGFLIVMERPANCMDLFDMVSVHGP-----------------LNEDMGK-----FIFKQVITTVFNMYSKHGLLHRDIKDENLIVNMNT ..| ...| . . . |||| .. ||... . . . | | |.|.|.. . .|.. .||||| ||.... | IVKMFYCFQDKQNIYIVMEY-CEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNG G--EVKLVDFGATAYAEKATKKEFQ------------------GTRSYC----PPEWFRD-QLYLP--LEATSWSLGVLLFILLTGKLPFR--------- . ..|. ||| . .. ... || .| .|| .. . . . .. |||||.|. .|.|..|| KNYYIKIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQ -------------NEIQICLGNVKFPP--------DLSKEVCQLVK----SCLTTSTSARASLAQIAAHPWM . .|. .|..||. ..|.|. ... ..| . | .. || |||. LITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF |
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Kinase | prk-1.AA | Ciliate-E2 | 34-69 | 22 | 5.2e-08 | 23.56 | In-house | 1-53 (365) | Show / Hide |
Range on Protein: 34-69 Range on HMM: 1-53/365 Sequence Identity: 22% (12 aa) YEVLDEIGRGGFGIVYEATTRQDGQQP-----------------VAVKFVQHK |... ||.|.||.||... .....| |..|.. | YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMK |
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Kinase | prk-1.AA | Ciliate-E2-Unclassified | 34-64 | 38 | 6.8e-08 | 23.48 | In-house | 1-30 (352) | Show / Hide |
Range on Protein: 34-64 Range on HMM: 1-30/352 Sequence Identity: 38% (12 aa) YEVLDEIGRGGFGIVYEATTRQDGQQPVAVK |... ||.||||.||.. .... | | | YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMK |
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Kinase | prk-1.AA | CAMKL | 34-66 | 33 | 7.8e-08 | 20.93 | In-house | 1-33 (297) | Show / Hide |
Range on Protein: 34-66 Range on HMM: 1-33/297 Sequence Identity: 33% (11 aa) YEVLDEIGRGGFGIVYEATTRQDGQQPVAVKFV |......|.|.|| | || .. .. ||.|.. YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKII |
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Kinase | prk-1.AA | TyrKc | 34-286 | 18 | 1.9e-07 | -102.37 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 34-286 Range on HMM: 1-280/280 Sequence Identity: 18% (57 aa) YEVLDEIGRGGFGIVYEATTRQDGQQPVAVKFVQHKHVRSWTMTCRQLIPSEVCHLETC-EDIPGVIKILDWFANS-------KGFLIVMERPANCMDLF . ....|.| ||.||..| . ..|||| ... . |. . .| . . | ..... . . .|||| .. || ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA--------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPH-GDLK DMVSVHGPLNEDMGKFIFKQVITTVFNMYS-------------KHGLLHRDIKDENLIVNMNTGEVKLVDFGATAYAEKA--------TKKEFQ--GTRS | |.| .. . | .... |||. | |. | || ||| . . . ... . |... DYLRKHRPK-------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKT -----YCPPEWFRDQLYLPLEATS----WSLGVLLF-ILLTGKLPFRNEIQ-----------ICLGNVKFPPDL---------SKEVCQLVKSCLTTSTS ..|| ... . |. || ||... |. |. | ..|| . |. .|. ..|. |. |.| . MLPIRWMAPECINYGKF-----TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPE ARASLAQIAAHPWM | . ..| | . DRPTFSEI--HECF |
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Kinase | prk-1.AA | Pkinase_Tyr | 34-64 | 35 | 0.000754 | 13.66 | Pfam | 1-34 (270) | Show / Hide |
Range on Protein: 34-64 Range on HMM: 1-34/270 Sequence Identity: 35% (12 aa) YEVLDEIGRGGFGIVYEATTR---QDGQQPVAVK . . ..|.| || ||..| . .....||||| ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVK |
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Kinase | prk-1.AA | MARK | 34-67 | 32 | 0.002913 | 6.71 | In-house | 1-33 (262) | Show / Hide |
Range on Protein: 34-67 Range on HMM: 1-33/262 Sequence Identity: 32% (11 aa) YEVLDEIGRGGFGIVYEATTRQDGQQPVAVKFVQ |..| .|| |... |. |. . | . ||.|... YKMLKTIGHGSYAKVKLACHKHTG-RKVAIKIYE |
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Kinase | prk-1.AA | QIK | 34-54 | 38 | 0.326654 | 1.0 | In-house | 1-21 (272) | Show / Hide |
Range on Protein: 34-54 Range on HMM: 1-21/272 Sequence Identity: 38% (8 aa) YEVLDEIGRGGFGIVYEATTR |.. ||.| |..| |. | YDIERTIGKGNFAVVKLARHR |