Gene F09A5.2 (Nematode worm)

F09A5.2

Species: Nematode worm
Alias: F09A5.2x=(rrhkd..ktdd), F09A5.2, CE09274, YS3J_CAEEL, aSWK396
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: X: 13138834-13143498, WormBase Genetic Map location: X:11.22,

Classification

Group: TK
Family: KIN6

Sequence

Name Sequence Type Origin Length Description Download
F09A5.2.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 278 Kinase domain by global Sugen HMM Fasta, JSON
F09A5.2.AA Protein Genbank 894 None Fasta, JSON

Protein domain

Protein domains of F09A5.2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase F09A5.2.AA KIN6 617-782 61 3.9e-131 435.74 In-house 128-305 (305) Show / Hide 
Range on Protein: 617-782
Range on HMM: 128-305/305
Sequence Identity: 61% (109 aa)

CPIEAD-----MCLRIKDLVSIAWQVADGMSYLASKNFIHRDLAARNILLTKSL---TAKVSDFGLCR--YMDSALYTAKGGR-LPIKWMSVEALKLYEF
||.|..     ||.|.|||...|||..|||.||.|||.|||||||||.|.|...   |.|.|||||||  |||...||.|||| ||||||..|.||.|||
CPDENSRYDDMMCIRHKDLYMFAWQICDGMEYLHSKNCIHRDLAARNVLVTEGCRMKTCKISDFGLCRYPYMDQFQYTSKGGRYLPIKWMAPECLKHYEF

STKTDVWSFGVLLFEIFSMGDVPYPTIQ-QVDMLEHLLAGGRLSQPLKCPNEIFNIMQKCWAEKPEDRPEFNEMRGEI
|.|.||||||||.||.||.||||||..| ...|.||...|.|...|..||.||..|||.||.|||.|||||||||...
SYKSDVWSFGVLMFEMFSLGDVPYPEMQRPTEMIEHHRSGRRPKHPKWCPEEIYDIMQSCWQEKPDDRPEFNEMRMQF
Pkinase_Tyr F09A5.2.AA Pkinase_Tyr 464-782 35 2.3e-128 435.34 Pfam 1-270 (270) Show / Hide 
Range on Protein: 464-782
Range on HMM: 1-270/270
Sequence Identity: 35% (118 aa)

VQEDHLLGNGAFANVYKGIVKGKIPLLVVNNSLNMTVESENNGHYEAAIKKLPAHADEQN--HLDFFHEIDFMKRLGHHPHVISMLGCVSNPYEP---LI
.. .. || ||| .||||. ||                .. |.... |.|.|. .|....  . ||..|.  || |||||......|...   ||   .|
ITFGKKLGEGAFGEVYKGTWKG----------------DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYI

VVEYCARGDLLKFLRRHKDYVLMNRVHIELCISIYKFKLKLRPNIEISKISFQNKTDDCPIEADMCLRIKDLVSIAWQVADGMSYLASKNFIHRDLAARN
|.||.. ||||..||.|.                                           | .  | .|||....||.|.||.||.|||.|||||||||
VMEYMPHGDLLDYLRKHR-------------------------------------------EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARN

ILLTKSLTAKVSDFGLCRYM--DSAL-YTAKGGRLPIKWMSVEALKLYEFSTKTDVWSFGVLLFEIFSMGDVP-YPTIQQVDMLEHL-LAGGRLSQPLKC
.|.|.....|..||||.|..  |.   ....||.||||||. |... ..|.||.||||||||..|||. |. | || .   ...|..   |.|. .| .|
CLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENC

PNEIFNIMQKCWAEKPEDRPEFNEMRGEI
| || ..|..||...||||| | | . ..
PDEIYDLMKQCWHYDPEDRPTFSEIHEQL
TyrKc F09A5.2.AA TyrKc 464-782 32 3.4e-126 426.47 SMART 1-280 (280) Show / Hide 
Range on Protein: 464-782
Range on HMM: 1-280/280
Sequence Identity: 32% (114 aa)

VQEDHLLGNGAFANVYKGIVKGKIPLLVVNNSLNMTVESENNGHYEAAIKKLPAHADEQNHLDFFHEIDFMKRLG-HHPHVISMLGCVSNP-------YE
.. .. ||.|||  ||||. |                       .. |.|.| ..|    . || .|.  |..|| |||... ..|... .         
ITLGKKLGEGAFGEVYKGTWK-----------------------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEP

PLIVVEYCARGDLLKFLRRHKDYVLMNRVHIELCISIYKFKLKLRPNIEISKISFQNKTDDCPIEADMCLRIKDLVSIAWQVADGMSYLASKNFIHRDLA
..||.||.. |||...||.|..                                               |  |||.|..||.|.||.||.|||.||||||
LMIVMEYMPHGDLKDYLRKHRPK----------------------------------------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLA

ARNILLTKSLTAKVSDFGLCRYMDSA--------LYTAK---GGR--LPIKWMSVEALKLYEFSTKTDVWSFGVLLFEIFSMGDVPYPT-----IQQVDM
|||.|... .|.|.|||||.|. ..          |..|   ||.  |||.||. |... ..|.||.|||||||...|||. |. |||      .   ..
ARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEV

LEHLLAGGRLSQPLK--------CPNEIFNIMQKCWAEKPEDRPEFNEMRGEI
.|.. .|.|. ||          || |...||..||.|.||||| |.| . ..
IEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase F09A5.2.AA TK 464-782 23 9.20000000001e-103 345.39 In-house 1-486 (486) Show / Hide 
Range on Protein: 464-782
Range on HMM: 1-486/486
Sequence Identity: 23% (117 aa)

VQEDHLLGNGAFA---NVYKGIVKGKIPLLVVNNSLNMT-----VESENNGHYEAAIKKLP--AHADEQNHLD--------------FFHEIDFMKR-LG
..  . || |.|     ||||...|..|.   .....||      .....|. . |.| |   ...... ..|              . .|.  |.. ||
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

HHPHVISMLGCVSNP------------YEPLIVVEYCARGD----LLKFLRRHKDYVLMNRVHIE------------LCISIYKFKLKLRPNIEISKISF
|||......|... .              ..||.||.. ||    |...||.....   .  ...            .|                    .
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHC--------------------M

QNK-------------------TDDCPIEADMCLRIKDLVS-------------------IAWQVADGMSYLASK------NFIHRDLAARNILLTKSLT
  |                    || . .. . |. |||..                   ..||.|.||.||.||      ||.||||||||.|......
--KGDITYSHESNSPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNV

-----------AKVSDFG--------LCRYMDS--ALYTAK------------------------GGRLPIKWMSVEALKLYE---------FSTKTDVW
           .|..|||        |.|...|    |...                        ||.|||.||. |.|.  .         |.||.|||
CKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVW

SFGVLLFEIFSMGDVPYPT-IQQ---------VDMLEHLLAGGRL--------------SQPLKCP--------------NEIFNIMQKCWAEKPEDRPE
|||||..|||. |..||.  .            ...|.| .||||               ||  ||               |.. .||.||...||||| 
SFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPT

FNEMRGEI
| ... ..
FSQLHEQL
Kinase F09A5.2.AA UTK 464-782 26 2e-85 290.13 In-house 1-296 (296) Show / Hide 
Range on Protein: 464-782
Range on HMM: 1-296/296
Sequence Identity: 26% (95 aa)

VQEDHLLGNGAFANVYKGIVK---GKIPLLVVNNSLNMTVESENNGHYEAAIKKLPAHADEQNHL---DFFHEID---FMKRLGHHPHVISMLGCVSNPY
||   .|| ||| .|.|. ..   .  ....| .  .                  . ....|..    ||  |     .||.. .||.|. ..| ...  
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQ-----------------HHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEE

EPLIVVEYCARGDLLKFLRRHKDYVLMNRVHIELCISIYKFKLKLRPNIEISKISFQNKTDDCPIEADMCLRIKDLVSIAWQVADGMSYLASKNFIHRDL
 ..||.||...|||...||||.. .                                        ...  |.  .... ||..|.||.||.|..|.||||
PWMIVTEYMENGDLRSYLRRHRPTPP---------------------------------------ACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDL

AARNILLTKS-------LTAKVSDFG---LCRYMD----------SALYTAKG-GRLPIKWMSVEALKLY-EFSTKTDVWSFGVLLFEIFSMGDVPYPTI
||||.|....       ...|..|||   ..|..           | .|.| . .|.||.||. |||     |.||.|||||||...||...| .||| .
AARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGM

QQVDMLEHLLAGG--RLSQPLKCPNEIFNIMQKCWAEKPEDRPEFNEMRGEI
  .. .. ...||  |. .|  || .....|..||.  |..|| | ... ..
SNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase F09A5.2.AA KIN6 464-579 54 6.7e-77 253.64 In-house 1-116 (305) Show / Hide 
Range on Protein: 464-579
Range on HMM: 1-116/305
Sequence Identity: 54% (63 aa)

VQEDHLLGNGAFANVYKGIVKGKIPLLVVNNSLNMTVESENNGHYEAAIKKLPAHADEQNHLDFFHEIDFMKRLGHHPHVISMLGCVSNPYEPLIVVEYC
...||.||.|||.|||||..|||.|.....|..||..|.........|.|.||.||||..|.||.|||.|||.||||||...|||||.|.|.|..|||||
IHKDHKLGHGAFCNVYKGKIKGKSPIMQWINRVNMRIEMMRYQDCQCAVKMLPSHADEMAHHDFMHEIAFMKQLGHHPHLVNMLGCVTNSYKPCLVVEYC

ARGDLLKFLRRHKDYV
...||||.||  . |.
CHMDLLKYLRNRCQYM
Kinase F09A5.2.AA Src 505-782 32 1.5e-71 242.3 In-house 21-255 (255) Show / Hide 
Range on Protein: 505-782
Range on HMM: 21-255/255
Sequence Identity: 32% (91 aa)

NGHYEAAIKKLPAHADEQNHLDFFHEIDFMKRLGHHPHVISMLGCVSNPYEPLIVVEYCARGDLLKFLRRHKDYVLMNRVHIELCISIYKFKLKLRPNIE
||. . |.| | .        .|  |.  || |  |.......  .|     .|| || ..| ||..|..                              
NGNTKVAVKTLKPGT--MSPEAFLQEAQIMKKL-RHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKK------------------------------

ISKISFQNKTDDCPIEADMCLRIKDLVSIAWQVADGMSYLASKNFIHRDLAARNILLTKSLTAKVSDFGLCRYMD--SALYTAKGG-RLPIKWMSVEALK
               .    |....|...|.|||.||.|| |.|.|||||||||.|  ... .|| |||| | ..     |.|. | ..||||.  ||. 
--------------DGEGRHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAIN

LYEFSTKTDVWSFGVLLFEIFSMGDVPYPTIQQVDMLEHLLAGGRLSQPLKCPNEIFN-IMQKCWAEKPEDRPEFNEMRGEI
   |..|.||||||.|| ||.. | ||||  .  . |... .| |. .| .|| |... ||..|| ..||.|| |  ..   
YGRFTIKSDVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase F09A5.2.AA TK-Unique 625-782 43 1.4e-69 237.46 In-house 128-294 (294) Show / Hide 
Range on Protein: 625-782
Range on HMM: 128-294/294
Sequence Identity: 43% (73 aa)

LRIKDLVSIAWQVADGMSYLAS--KNFIHRDLAARNILLTKSLTAKVSDFGLCRY-MDSALYTAKG--GRLPIKWMSVEALK--LYEF-STKTDVWSFGV
.  |||...|||.| ||.||||  |...||||.|||.|||  ...|..|||. |. ..   |  ..  ||.||.||. |.||     . .||.|||||||
ISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGV

LLFEIFSMGDVPYPTIQQVDMLEHLLAGGRLSQPLKC-PNEIFNIMQKCWAEKPEDRPEFNEMRGEI
|..|||..|  ||| . . |..|.. .| |. || .| ..|..|.|. || ..||.|| | . . ..
LMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase F09A5.2.AA Met 625-776 42 1.9e-68 223.41 In-house 101-271 (271) Show / Hide 
Range on Protein: 625-776
Range on HMM: 101-271/271
Sequence Identity: 42% (73 aa)

LRIKDLVSIAWQVADGMSYLASKNFIHRDLAARNILLTKSLTAKVSDFGLCRYM--DSALYTAKG--G--RLPIKWMSVEALK--------LYE-FSTKT
. ..||.. . ||| ||.|.||. |.|||||.|| .| ...| || |||||| |  |  .| ..   .  |||.|||  | |.         |  |.||.
PCVRDLIEFCHQVAKGMMYMASQKFVHRDLACRNCMLDEHFTVKVADFGLCRDMDYDKEYYSQMHHTHPARLPVKWMAPECLQQGVCLGCPTYRQFTTKS

DVWSFGVLLFEIFSMGDVPYPTIQQ-VDMLEHLLAG--GRLSQPLKCPNEIF-NIMQKCWAEKPEDRPEFN
|||||||.. | .  | .||| .   .| .  |  |   ||.||  ||  .   .|..||  .|||||.| 
DVWSFGVVMWELMTRGAPPYPHVDNWFDITHWLHQGETRRLPQPEYCPDHLYTDVMLCCWHANPEDRPQFS
Kinase F09A5.2.AA SRM 625-783 41 3.2e-64 213.68 In-house 94-253 (253) Show / Hide 
Range on Protein: 625-783
Range on HMM: 94-253/253
Sequence Identity: 41% (67 aa)

LRIKDLVSIAWQVADGMSYLASKNFIHRDLAARNILLTKSLTAKVSDFGLCRYMDSALY-TAKGGRLPIKWMSVEALKLYEFSTKTDVWSFGVLLFEIFS
|.| .|. .|.||| ||.|| ..|.|||||||||.| .  .. || |||| | .    |    . . |.||   ||.    .|.| ||||||.||.|.|.
LPIPHLLDFACQVAEGMCYLEEQNYIHRDLAARNVLVGDNNLCKVGDFGLARLIKDDIYSPSHDHNIPYKWTAPEAANYRHYSQKSDVWSFGILLHEMFT

MGDVPYPTIQQVDMLEHLLAGGRLSQPLKCPNEIFNIMQKCWAEKPEDRPEFNEMRGEIT
 | .|||       .    .| |.  |. || |..  | .||   ||.|| |  .|   |
YGQCPYPGMTNHETFQQIDRGYRMPCPAECPPEVHKLMLECWCRDPEQRPCFKDLREKLT
Kinase F09A5.2.AA RTKB 625-782 41 2e-63 212.69 In-house 106-264 (264) Show / Hide 
Range on Protein: 625-782
Range on HMM: 106-264/264
Sequence Identity: 41% (66 aa)

LRIKDLVSIAWQVADGMSYLASKNFIHRDLAARNILLTKSLTAKVSDFGLCRYMDSALYTAKGGRLPIKWMSVEALKLYEFSTKT-DVWSFGVLLFEIFS
|. . ||. . |.| ||..| ..| |||||.|||.|....|. |..|||. | .|   |.    |||||||  | ..   ..||  |||||||  .||||
LKQAQLVDFCHQIACGMAFLHQHNVIHRDLCARNVLVDQQLHCKICDFGMAREIDHECYETTCTRLPIKWMAPESWAHRIYTTKSGDVWSFGVTMWEIFS

MGDVPYPTIQQVDMLEHLLAGGRLSQPLKCPNEIFNIMQKCWAEKPEDRPEFNEMRGEI
.| .||.. . .|....|  | || .|   | ... |||.||.. ...|| | |. .. 
LGGTPYQQYRNGDIFYWLESGHRLPKPRQMPQAADHIMQMCWQMEAQHRPDFDELVDAF
Kinase F09A5.2.AA FGFR 600-782 42 2.8e-63 214.51 In-house 100-293 (293) Show / Hide 
Range on Protein: 600-782
Range on HMM: 100-293/293
Sequence Identity: 42% (83 aa)

RPNIEISKISFQNKTDDCPIEADMC--------LRIKDLVSIAWQVADGMSYLASKNFIHRDLAARNILLTKSLTAKVSDFGLCRYMDSALYTAKG--GR
||  .  | . |. ||. |  .           |  |||||.|.||| || ||||.  |||||||||.| |     |..|||| |   .  |  |   ||
RPPGMDYKKDSQEYTDYKPRKPEQQDDIELIPNLTQKDLVSCAYQVARGMEYLASRKCIHRDLAARNVLVTDDYVMKICDFGLARDIHCIDYYRKTTNGR

LPIKWMSVEALKLYEFSTKTDVWSFGVLLFEIFSMGDVPYPTIQ-QVDMLEHLLAGGRLSQPLKCPNEIFNIMQKCWAEKPEDRPEFNEMRGEI
||||||  |||    . .. ||||.|||| ||.  |. |||.|    .. . |  | |.  | .|..||. .|  || .||..|| | ..  ..
LPIKWMAPEALFDRVYTHQSDVWSYGVLLWEIMTYGGQPYPHIPSVEELYKYLKEGHRMEKPHNCSQEIYHMMCQCWHFKPCQRPTFKQLVEYL
Kinase F09A5.2.AA VEGFR 628-782 45 1.5e-60 207.47 In-house 173-332 (332) Show / Hide 
Range on Protein: 628-782
Range on HMM: 173-332/332
Sequence Identity: 45% (73 aa)

KDLVSIAWQVADGMSYLASKNFIHRDLAARNILLTKSLTAKVSDFGLCRY-MDSA-LYTAKGG--RLPIKWMSVEALKLYEFSTKTDVWSFGVLLFEIFS
.||.. . ||| || .|||.. ||||||||||||. . . | .|||| |  . .   | .||.  |||||||. |..    ..|. ||||.||.| ||||
EDLICYSFQVARGMEFLASRKCIHRDLAARNILLCENNVVKICDFGLARHGIYKDPDYVRKGDQGRLPIKWMAPESIFDKVYTTYSDVWSYGVFLWEIFS

MGDVPYPTIQ-QVDMLEHLLAGGRLSQPLKCPNEIFNIMQKCWAEKPEDRPEFNEMRGEI
 | .|||..|   .    | .| |.  |  |. ||  ||. || . || || | |     
LGGSPYPGVQIDEEFCNRLKDGYRMRAPDYCTPEIYHIMLDCWHKEPEERPHFSELVEHL
Kinase F09A5.2.AA Pkinase 464-773 17 2.8e-31 111.67 Pfam 1-282 (293) Show / Hide 
Range on Protein: 464-773
Range on HMM: 1-282/293
Sequence Identity: 17% (63 aa)

VQEDHLLGNGAFANVYKGIVKGK-IPLLVVNNSLNMTVESENNGHYEAAIKKLPAHADEQNHLD-FFH--EIDFMKRLGHHPHVISMLGCVSNPYEPLIV
 .    .| |.|. |||.. ||  .                     . |.|... . .. . .   ..  ||  |||| .||... ..... .. .. .|
YHIGRKIGSGSFGCVYKCHHKGTGK---------------------IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMV

VEYCARG----DLLKFLRRHKDYVLMNRVHIELCISIYKFKLKLRPNIEISKISFQNKTDDCPIEADMCL--RIKDLVSIAWQVADGMSYLASKNFIHRD
 |||  |    ||  ....                                             ... |.    ... ....|.. |. |. |...||||
MEYCEGGLYVMDLFDYIST---------------------------------------------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRD

LAARNILLTKSLTA----KVSDFGLCRYM-DSALYTAKGGRLPIKWMSVEALK-LYEFSTKTDVWSFGVLLFEIFSMGDVPYPTI----QQVDMLEHLLA
|   |||. .  .     |..||||.. .       ...    . .|. | ..   . ..| |.||.|..|.| .. |  |.|        .|... .  
LKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICR

GGR----LSQPLKCP-------------------NEIFNIMQKCWAEKPEDRP
 ..     . | .|.                    |   .. .|.. .|..||
IMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRP
Kinase F09A5.2.AA S_TKc 464-784 19 2e-27 98.32 SMART 1-231 (231) Show / Hide 
Range on Protein: 464-784
Range on HMM: 1-231/231
Sequence Identity: 19% (66 aa)

VQEDHLLGNGAFANVYKGIVKGKIPLLVVNNSLNMTVESENNGHYEAAIKKLPAHADEQNHLDFFHEIDFMKRLGHHPHVISMLGCVSNPYEPLIVVEYC
 .   ..| |||. |||.. |.                     . . |||...         ..  ||. .|.  |||... ....  .  .  .| |||
YEILRKIGKGAFGKVYKCRHKK--------------------TGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYC

AR--GDLLKFLRRHKDYVLMNRVHIELCISIYKFKLKLRPNIEISKISFQNKTDDCPIEADMCLRIKDLVSIAWQVADGMSYLASKNFIHRDLAARNILL
    |||........   |                                         .  .   .  ....|..... |. |...|||||   ||||
DGDLGDLFDYIKKRGRHGL-----------------------------------------RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILL

TKSLTAKVSDFGLCRYMDSALYTAKGGRLPIKWMSVEALKLYEFST-KTDVWSFGVLLFEIFSMGDVPYPTIQQVDMLEHLLAGGRLSQPLKCPNEIFNI
..  . |..||||.| .       .       .|. | |    ... | |.||.|..|.| .. |  |.|  |.  |.....           . |  ..
DE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC-GYPPFP--QMQMMFKKIG-----------SPEAKDF

MQKCWAEKPEDRPEFNEMRG-------EITV
..||.   ||.||   |             .
IRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase F09A5.2.AA TK-Unique 464-574 29 4.6e-21 69.45 In-house 1-98 (294) Show / Hide 
Range on Protein: 464-574
Range on HMM: 1-98/294
Sequence Identity: 29% (33 aa)

VQEDHLLGNGAFANVYKGIVKGKIPLLVVNNSLNMTVESENNGHY-EAAIKKLPAHADEQNHLDFFHEIDFMKRLGHHPHVISMLGCVSNPY-EPLIVVE
.  . ..| |||  |..| |.|..               .....   .|.|.| ..|... . ||. || .|| || ||.....|||   .   ..|. |
LEVGDVIGEGAFGQVWRGEVWGIW---------------KHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIME

YCARGDLLKFLRR
||..|.|...||.
YCPCGNLQHYLRT
Kinase F09A5.2.AA FGFR 511-575 33 1.3e-08 25.47 In-house 35-99 (293) Show / Hide 
Range on Protein: 511-575
Range on HMM: 35-99/293
Sequence Identity: 33% (22 aa)

AIKKLPAHADEQNHLDFFHEIDFMKRLGHHPHVISMLGCVSNPYEPLIVVEYCARGDLLKFLRRH
|.|.| . . ..   |   |.  ||  | |. .|  ||| .    . ..||||..| |  ||| .
AVKMLKMNHTDKDLSDLVSEMEMMKMIGKHKNIINLLGCCTQEGPLYVIVEYCHHGNLRDFLRAR
Kinase F09A5.2.AA RTKB 511-573 41 4.7e-08 23.26 In-house 32-94 (264) Show / Hide 
Range on Protein: 511-573
Range on HMM: 32-94/264
Sequence Identity: 41% (27 aa)

AIKKLPAHADEQNHLDFFHEIDFMKRLGHHPHVISMLG-CVSNPYEPLIV-VEYCARGDLLKFLR
| | |.. | .  . ||  |. .|| || ||.|| ..| |     ||.|. ||.|  | |  .||
AAKVLKPGASYEERQDFCSEMTVMKELGWHPNVIGIIGHCLQD--EPYILLVELCELGNLRDYLR
Kinase F09A5.2.AA VEGFR 511-578 35 8.4e-08 25.72 In-house 33-103 (332) Show / Hide 
Range on Protein: 511-578
Range on HMM: 33-103/332
Sequence Identity: 35% (25 aa)

AIKKLPAHADEQNHLDFFHEIDFMKRLGHHPHVISMLGCVSN--PYEPLIV-VEYCARGDLLKFLRRHKDY
| |.| . |.   |     |.  .. .|||  | ..|||.    .  || | ||||  | |. .||   .|
AVKMLKEGATASEHRALMSELKMLIHIGHHLNVVNFLGCCTKNIQKGPLMVIVEYCCFGNLSNYLRTKRMY
Kinase F09A5.2.AA Met 511-573 34 1.6e-05 13.78 In-house 30-95 (271) Show / Hide 
Range on Protein: 511-573
Range on HMM: 30-95/271
Sequence Identity: 34% (23 aa)

AIKKLP--AHADEQNHLDFFHEIDFMKRLGHHPHVISMLG-CVSNPY-EPLIVVEYCARGDLLKFLR
|.| |      |.|    |. |   || . .||.| | .| | .     |..| .| . |||..| |
ACKSLHGERITDIQHISQFLREGIMMKHF-DHPNVLSLIGICLDPEGHMPWVVLPYMKHGDLKTFIR
Kinase F09A5.2.AA RTKB 464-484 42 3.8e-05 13.33 In-house 1-21 (264) Show / Hide 
Range on Protein: 464-484
Range on HMM: 1-21/264
Sequence Identity: 42% (9 aa)

VQEDHLLGNGAFANVYKGIVK
|. .. ||||||..|... |.
VWLGEKLGNGAFGEVFQAWVR
Kinase F09A5.2.AA Src 464-488 28 0.029204 3.43 In-house 1-25 (255) Show / Hide 
Range on Protein: 464-488
Range on HMM: 1-25/255
Sequence Identity: 28% (7 aa)

VQEDHLLGNGAFANVYKGIVKGKIP
..    ||.| |  |..|. .|...
IKLCRKLGQGQFGEVWMGYWNGNTK
Kinase F09A5.2.AA SRM 526-580 29 0.1136 1.17 In-house 41-94 (253) Show / Hide 
Range on Protein: 526-580
Range on HMM: 41-94/253
Sequence Identity: 29% (16 aa)

DFFHEIDFMKRLGHHPHVISMLGCVSNPYEPLIVVEYCARGDLLKFLRRHKDYVL
..  ||. || | |  |.|..   .|      |. |  ..| |...||   . .|
MLQKEIQAMKKLRHK-HIIRLHAVCSVGDPVYIITELMRKGNLQQYLRDSDEKAL