Gene Wee1 (Mouse)

Wee1

Species: Mouse
Alias: Wee1
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP ,
Annotation:

Classification

Group: Other
Family: WEE
Subfamily: WEE1

Sequence

Name Sequence Type Origin Length Description Download
Wee1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 271 Kinase domain by global Sugen HMM Fasta, JSON
Wee1.NA RNA Sugen 3419 None Fasta, JSON
Wee1.AA Protein Sugen 646 None Fasta, JSON

Protein domain

Protein domains of Wee1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Wee1.AA WEE 298-568 47 1.3e-168 566.49 In-house 1-297 (297) Show / Hide 
Range on Protein: 298-568
Range on HMM: 1-297/297
Sequence Identity: 47% (142 aa)

FHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLG------QHPHVVRYFSAWAEDDHMLIQNEYCNGGS--LADAISE
|.|..|||.|.||.|.||..|.||||||||.||.|..|. ....||||||||.|||      .|||.|||.|||.|||||.||.|||||||  |...|..
FQEVQKIGEGSFGEVYKCRCRIDGCIYAIKKSKQPFRGYSERKRALREVYAHMVLGQIMDCDHHPHIVRYYSAWEEDDHMYIQMEYCNGGSNLLQFWIQQ

NYRVMSYLTEVELKDLLLQVGRGLRYIHSM-SLVHMDIKPSNIFISRTSIPNAV---SEEGDEDDWISNKVMFKIGDLGHVTRIS----SPQVE-EGDSR
... . .|.| .....|... .||..|||. ..|||||||.|||||. ...|..   ......|.| .| .|.||||.||||...    .|..| |||||
CHNWNHWLPEWMIWQILVDICQGLHHIHSNCGMVHMDIKPENIFISKKMNCNQIVNNDQQNNNDWW-FN-MMCKIGDFGHVTDMNSNNNNPHQEQEGDSR

FLANEVLQE--NYSHLPKADIFALALTVVCAAGAEPLPRNGEQWHEIRQG-------RLP--RIPQVLSQEVTELLRVMIHPDPERRPSAMELVKHSVL
..|.|.||.  .|.||.|||||.|..|....|....||.||..||.||||       ..|  .... .|||...|...|.|||||.||....|..|.||
YMAPEILQGYYHYTHLYKADIFSLGITIYELACNMDLPKNGDWWHQIRQGDLSFDKNQIPFPEFDNIISQELKQLIKWMMHPDPEQRPTCQQLLQHPVL
Kinase Wee1.AA Pkinase 298-568 25 8.7e-77 266.21 Pfam 1-293 (293) Show / Hide 
Range on Protein: 298-568
Range on HMM: 1-293/293
Sequence Identity: 25% (79 aa)

FHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALR--EVYAHAVLGQHPHVVRYFSAWAEDDHMLIQNEYCNGG----SLADAIS-EN
.| ..||||| ||.|.||... .|.|.|.|. ||. . |  .|...|  |.. .. | .||..||.. .. ..||. .  |||.||    .|.| || ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

YRVMSYLTEVELKDLLLQVGRGLRYIHSMSLVHMDIKPSNIFISRTSIPNAVSEEGDEDDWISNKVMFKIGDLGH-----VTRISSPQVEEGDSRFLANE
..... ..| |.|. ..|. ||| |.|||. .| |.||.||.|...  ..|               ..||.| |        . | ...  | ....| |
HGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA---------------CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPE

VLQENYSHLPKADIFALALTVVCAAGAEPLPRNGEQWHEIRQGRLPRIPQVLS-------------------------------QEVTELLRVMIHPDPE
|....  . ||.|.... ... . .  .|. ..   ||.     . .| ....                               .|  .... ....||.
VIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHC-WHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPK

RRPSAMELVKHSVL
.||.|.....|  .
KRPTAEQILQHPWF
Kinase Wee1.AA S_TKc 298-568 23 3e-38 134.3 SMART 1-231 (231) Show / Hide 
Range on Protein: 298-568
Range on HMM: 1-231/231
Sequence Identity: 23% (67 aa)

FHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQHPHVVRYFSAWAEDDHMLIQNEYCNG--GSLADAISENYRVM-
.. |.|||.| ||.|.||... .| |.|||. |         ....||.  .    .||..|... .. . ||. .  |||.|  |.| | | .. |   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

-SYLTEVELKDLLLQVGRGLRYIHSMSLVHMDIKPSNIFISRTSIPNAVSEEGDEDDWISNKVMFKIGDLGHVTRISSPQVEEGDSRFLANEVLQENYSH
 ....| . . .. |. ..| |.||.  .| |.||.||....                       ||.| |  ...       |   ..| |||    ..
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---------------------HIKICDFGLARQL---TTFCGTPWYMAPEVL----GY

LP-KADIFALALTVVCAAGAEPLPRNGEQWHEIRQGRLPRIPQVLSQEVTELLRVMIHPDPERRPSAMELVK-------HSVL
 . |.|. ..  ..   .  .|. .  ..   ... .        |.|. ...| . . |||.||.| |. .       |  .
GKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG--------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Wee1.AA STE 298-568 19 1.3e-34 119.71 In-house 1-359 (359) Show / Hide 
Range on Protein: 298-568
Range on HMM: 1-359/359
Sequence Identity: 19% (74 aa)

FHELEKIGSGEFGSVFKCVKRL---------------DGCIYAIKRSKKPLAGS---------------VDEQNALREVYAHAVLGQ-HPHVVRYFSAWA
.  .||||.| ||.|.|....                 |.|.|||. ..    .                ..|. |.|.  .  . . ||..|.|. .  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

ED-------DHMLIQNEYCNGGSLADAISENYRVMSYLT----------EVELKDLLLQVGRG-LRYIHSMSLVHMDIKPSNIFISRTSIPNAVSEEGDE
 .       |.  |  ||..|||| | | ..| .   |.          | ...  . |. .| | |.||.  .| ||||.||..               
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL---------------

DDWISNKVMFKIGDLGHVTRISS---------------PQVEEGDSRF----LANEVLQE-----NYSHLPKADIFALALTVVCAAGAEPL----PRNGE
          |. | |. .....                .... ..       | ||.|      .  .  |.||  | .|..  |  .|     .    
---------VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTPWMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRA

QWHEIRQ--------------GRLPRIPQ-------------------VLSQEVTELLRVMIHPDPERRPSAMELVK--HSVL
 .. ..               |  |..|.                    .|.|  . ..     ||. ||.| .| |  |. .
MFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase Wee1.AA Ciliate-E2 298-502 19 9.2e-31 102.81 In-house 1-282 (365) Show / Hide 
Range on Protein: 298-502
Range on HMM: 1-282/365
Sequence Identity: 19% (60 aa)

FHELEKIGSGEFGSVFKCVKRLDGC-----------------------IYAIKRS-KKPLAGSVDEQNALREVYAHA--VLGQ---------HPHVVRYF
.  ..|||.| ||||.|| ......                       |||.|.  |. .     |.. .||.       . .         ||......
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINC-FYKKI-NEKNILEQLNHPNIIKMY

SAWA--EDDHMLIQNEYCNGGSLADAISENYRVM-------SYLTEVELKDLLLQVGR---------------GLRYIHSMS-LVHMDIKPSNIFISRTS
 ..    |... .  |||.||.| | | .|.           |.|| | |..  |. .               .|.|.||    .| ||||.||..    
ECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

IPNAVSEEGDEDDWISNKVMFKIGDLGHVTRISSPQVEE-----------------------------------GDSRFLANEVLQ-ENYS-------HL
                     || |.|  .... .. ..                                   |   ..| |.|. ..|.       . 
--------------------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYD

PKADIFAL
 |.||..|
YKCDIWSL
Kinase Wee1.AA CAMK 303-434 21 3.4e-26 80.79 In-house 1-213 (425) Show / Hide 
Range on Protein: 303-434
Range on HMM: 1-213/425
Sequence Identity: 21% (45 aa)

KIGSGEFGSVFKCVKRLDG------------CIYAIKR-SKKPLAG-------------------------SVDEQNALREVYAHAVLG------QHPHV
..|.| || |..|. ....              .|||  .|| | .                          .|..| .||.  .  |       .||..
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRYFSAWAE-------------------DDHMLIQN---EYCNGG----SLADAISEN------------YRVMSYLTEVELKDLLLQVGRGLRYIHSMS
.. . ..                     |.|| .     ||| ||     | | | |.                 ..|| | . .  |.  ...|.||. 
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHSHN

LVHMDIKPSNIFIS
 || |.|| || ..
IVHRDLKPENILLD
Kinase Wee1.AA Ciliate-E2-Unclassified 298-502 21 1.2e-24 82.46 In-house 1-256 (352) Show / Hide 
Range on Protein: 298-502
Range on HMM: 1-256/352
Sequence Identity: 21% (58 aa)

FHELEKIGSGEFGSVFKCVKRLDG--------CIYAIKRSKKPLAGSVDEQNALREVYAH---------AVLGQ------HPHVVRYFSAWAEDDHMLIQ
.. ...||.| ||.|.||... ..        . . |. .|. .    .. | . |.  .           . |      ||..|..| .   .... | 
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

NEYCNGGSLADAIS-------------ENYRVMSYLTEVELK-----DLLLQVGRGLRYIHSMS-LVHMDIKPSNIFISRTSIPNAVSEEGDEDDWISNK
 |||.||.| . |.             .| .    .|| . |     ... |.  || |.|.    .| ||||.||...                    .
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK----------------N

VMFKIGDLGHVTRISSPQVEE-------------------GDSRFL----ANEVLQE-NYSHL--PKADIFAL
   || |.|   .. ... ..                   |  ...    | ||||. ||.|    |.||..|
YYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSL
Kinase Wee1.AA PEK 298-370 35 4.8e-22 72.95 In-house 1-88 (655) Show / Hide 
Range on Protein: 298-370
Range on HMM: 1-88/655
Sequence Identity: 35% (32 aa)

FHELEKIGSGEF-GSVFKCVKRLDGCIYAIKRSKKPLAG---------------SVDEQNALREVYAHAVLGQHPHVVRYFSAWAEDDH
|.|....|.|.| |.|.|.  .|||| ||||| | . ..               .  ....|||| . | | .||..|||..|| |...
FEEIQCLGKGGFGGQVYKVQNKLDGCYYAIKRIKLNWKQRKQPCITQECMIHKCKKHCEKVLREVKTLARL-NHPNIVRYHNAWIEKPE
Kinase Wee1.AA NEK 298-464 27 5e-20 67.54 In-house 1-168 (286) Show / Hide 
Range on Protein: 298-464
Range on HMM: 1-168/286
Sequence Identity: 27% (51 aa)

FHELEKIGSGEFGSVFKCVKRLDGCI-----YAIKRSKKPLAGSVDEQNAL-REVYAHAVLG--QHPHVVRYFSAWAEDD--HMLIQNEYCN-GGSLADA
. ...|||.| ||.|.|. .. || .     |..|. .     . . |||.  ||    .|   .||..|.|. .. |..  .. |  |||. || |.. 
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEV---RILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQK

---ISENYRVMSYLTEVELKDLLLQVGRGLRYIHSM-----SLVHMDIKPSNIFISRTSIPNAVSEEGDEDDWISNKVMFKIGDLG
   | ..     |. | .  | . |   .|.|.|..       .| ||||.|||...  .                 .  ||||.|
IKSIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDY---------------HNVKIGDFG
Kinase Wee1.AA PEK 373-435 25 8.8e-16 50.74 In-house 360-462 (655) Show / Hide 
Range on Protein: 373-435
Range on HMM: 360-462/655
Sequence Identity: 25% (26 aa)

IQNEYCNGGSLADAISEN--------------------YRVMS---------------------YLTEVELKDLLLQVGRGLRYIHSMSLVHMDIKPSNI
|| |||....| | |..|                    |  |.                     .. ........ |.  || ||||. ..| |.|||||
IQMEYCEKKTLRDWIDNNGCPVQFNYWRRNSCKNHYNNY-IMNQCCFQSTWSMNMRQWDENNCMFWDKDQCWRIFRQILEGLNYIHSQGMIHRDLKPSNI

FISR
|...
FLDC
Kinase Wee1.AA PEK 298-369 34 3.1e-14 42.74 In-house 1-78 (758) Show / Hide 
Range on Protein: 298-369
Range on HMM: 1-78/758
Sequence Identity: 34% (27 aa)

FHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPL-------AGSVDEQNALREVYAHAVLGQHPHVVRYFSAWAEDD
| . ...|.| ||.||.    .|.. |||||   |          .   .  .||| . | |  |.  ||||.|| | .
FEHIQCLGHGGFGVVFRAKNKVDMNNYAIKRITFPNSNNQSPTNRESAREKVMREVRTLAML-DHHNIVRYFNAWLETP
Kinase Wee1.AA TyrKc 298-568 19 1.3e-13 -2.62 SMART 1-280 (280) Show / Hide 
Range on Protein: 298-568
Range on HMM: 1-280/280
Sequence Identity: 19% (60 aa)

FHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLG-QHPHVVRYFSAWAED-------DHMLIQNEYCNGGSLADAISE
 . ..|.|.|.|| |.|.. .      |.|  |.       ..  .||      || .||..|| . .  ..       . ..|  ||. .|.| | . .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

NYRVMSYLTEVELKDLLLQVGRGLRYIHSMSLVHMDIKPSNIFISRTSIPNAVSEEGDEDDWISNKVMFKIGDLG---HVTRI-----SSPQVEEG---D
. .    |.  .| .  .|. .| .|.||. ..| |.   |. ...                       ||.| |    ..       |.         .
HRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-------------------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKG

SRF------LANEVLQEN-YSHLPKADIFALALTV--VCAAGAEPLPR-------NGEQWHEIRQGRLPRIPQV--------LSQEVTELLRVMIHPDPE
...      .| |..... ...  | |...   .   ..  |..| |        | |  . ..||. ...|.          ..|. .. .   | |||
GKTMLPIRWMAPECINYGKFTT--KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPE

RRPSAMELVKHSVL
 ||.  |.  |. .
DRPTFSEI--HECF
Kinase Wee1.AA PKR 298-365 44 2.6e-13 43.9 In-house 1-61 (272) Show / Hide 
Range on Protein: 298-365
Range on HMM: 1-61/272
Sequence Identity: 44% (30 aa)

FHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQHPHVVRYFSAW
|...|.|||| || |||   |.||  |.||| |        .  | .|| | | | .|  .|.| | |
FKDIEEIGSGGFGQVFKAKHRIDGKRYVIKRVK------YNNEKAEHEVQALAKL-DHVNIVHYHSCW
Kinase Wee1.AA GCN2 298-372 36 7.5e-13 40.93 In-house 1-79 (511) Show / Hide 
Range on Protein: 298-372
Range on HMM: 1-79/511
Sequence Identity: 36% (29 aa)

FHELEKIGSGEFGSVFK-CVKRLDGCIYAIKRSKKPLAGSVDEQN--ALREVYAHAVLGQHPHVVRYFSAWAE--DDHML
| |.. .| |.||.| |    ..||..||||. . . ..  ..     .|||   . | .|.|||||. ||.|  |. |.
FEEICCLGKGGFGQVVKNVRNMHDGRYYAIKKWPINWKQRKLPCKHKIMREVKLLCRL-HHQHVVRYYQAWIEKCDEPMV
Kinase Wee1.AA GCN2 373-433 42 2.8e-12 38.87 In-house 284-341 (511) Show / Hide 
Range on Protein: 373-433
Range on HMM: 284-341/511
Sequence Identity: 42% (26 aa)

IQNEYCNGGSLADAISENYRVMSYLTEVELKDLLLQVGRGLRYIHSMSLVHMDIKPSNIFI
|| ||| |..|...|...  .|      ||. .. |.  || ||||.. .| |.||||||.
IQMEYCEGKTLRQYIDNHGWCMDHD---ELWRYFRQILEGLNYIHSQGMIHRDLKPSNIFL
Kinase Wee1.AA PEK 370-472 29 3e-11 32.59 In-house 413-523 (758) Show / Hide 
Range on Protein: 370-472
Range on HMM: 413-523/758
Sequence Identity: 29% (34 aa)

HMLIQNEYCNGGSLADAISENYRVMSYLTEVELKDLLLQVGRGLRYIHSMSLVHMDIKPSNIFISRTSI-------PNAVSEEGDEDDWISNKVMFKIGD
.|.|| ..| . .| | .. . . |.   . . ... .|   |..||||. . | | |||||| |. |         |  |   .  |    ..  ||||
YMYIQMQLCRKETLKDWMRNR-CTMESRPWMHMLHWFHQICEGVNYIHSKGMIHRDLKPSNIFFSMDSQHHQQSSFSNISSSFEENSDGGHQII--KIGD

LGHVTRI----SSP
.| ||..    ..|
FGLVTDHTIVTPTP
Kinase Wee1.AA NEK 525-568 31 6.6e-10 31.47 In-house 240-286 (286) Show / Hide 
Range on Protein: 525-568
Range on HMM: 240-286/286
Sequence Identity: 31% (15 aa)

IRQG-RLPRIPQV--LSQEVTELLRVMIHPDPERRPSAMELVKHSVL
|..|   |.||.    ||.  .|.. |...||| |||. .. ... .
IMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase Wee1.AA PKR 371-433 39 1.2e-09 30.63 In-house 96-156 (272) Show / Hide 
Range on Protein: 371-433
Range on HMM: 96-156/272
Sequence Identity: 39% (25 aa)

MLIQNEYCNGGSLADAISENYRVMSYLTEVELKDLLLQVGRGLRYIHSMSLVHMDIKPSNIFI
. || |.|  | |   . .  |  . .  |   ||  |. .|  ||||  |.| |.||||||.
LFIQMEFCDKGTLEQWMRN--RRQEKVDKVLILDLYEQIVKGVDYIHSKKLIHRDLKPSNIFL
Kinase Wee1.AA Pkinase_Tyr 298-423 23 6.5e-09 30.81 Pfam 1-134 (270) Show / Hide 
Range on Protein: 298-423
Range on HMM: 1-134/270
Sequence Identity: 23% (33 aa)

FHELEKIGSGEFGSVFKCVKR----LDGCIYAIKRSKKPLAGSVD--EQNALREVYAHAVLGQHPHVVRYFSAWA-EDDH--MLIQNEYCNGGSLADAIS
 . ..|.|.|.||.|.|.. .     ...  |.|   |. | . .   .  .||.     ||.||..||.  .   ....  ..|  ||. .|.| |   
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

EN---YRVMSYLTEVELKDLLLQVGRGLRYIHSMSLVH
..    .    ||  .| .  .|. .|. | .|. ..|
KHREDKQP---LTMKDLLQMCWQIAKGMEYLESKNCIH
Kinase Wee1.AA PEK 525-568 21 3.5e-07 20.23 In-house 605-655 (655) Show / Hide 
Range on Protein: 525-568
Range on HMM: 605-655/655
Sequence Identity: 21% (11 aa)

IRQ------GRLP-RIPQVLSQEVTELLRVMIHPDPERRPSAMELVKHSVL
.|.      | .|  . ..   .  .... |...||. ||||... .|  .
LRDESIQFPGDFPPKWFDNKYPKQADFIQWMLSHDPQQRPSAQQILQHEFF
Kinase Wee1.AA GCN2 542-568 37 4.9e-07 20.21 In-house 485-511 (511) Show / Hide 
Range on Protein: 542-568
Range on HMM: 485-511/511
Sequence Identity: 37% (10 aa)

TELLRVMIHPDPERRPSAMELVKHSVL
....| .. .|| .||||..| .|. |
QDMIRWCLNHDPQKRPSAQQLLQHEFL
Kinase Wee1.AA PEK 540-568 24 3e-06 15.82 In-house 730-758 (758) Show / Hide 
Range on Protein: 540-568
Range on HMM: 730-758/758
Sequence Identity: 24% (7 aa)

EVTELLRVMIHPDPERRPSAMELVKHSVL
.. |..  |....|. ||.| .. .| . 
QEYEFIQQMMSMNPDERPTADQISMHDFF
Kinase Wee1.AA CAMK 522-568 20 6e-06 14.4 In-house 356-425 (425) Show / Hide 
Range on Protein: 522-568
Range on HMM: 356-425/425
Sequence Identity: 20% (14 aa)

WHEIRQGRLPRIPQV-----------------------LSQEVTELLRVMIHPDPERRPSAMELVKHSVL
.. |..|.   .|                         .|||.  |.| |  .|||.|... .  .|  .
FEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase Wee1.AA Ciliate-E2 533-568 24 4.6e-05 13.3 In-house 325-365 (365) Show / Hide 
Range on Protein: 533-568
Range on HMM: 325-365/365
Sequence Identity: 24% (10 aa)

IPQVLSQEVTELLRV----MIHPDPERRPS-AMELVKHSVL
... .|||.  |..     |.  ||| |.. . .. .|  .
SWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase Wee1.AA Ciliate-E2-Unclassified 533-568 20 0.000471 9.98 In-house 313-352 (352) Show / Hide 
Range on Protein: 533-568
Range on HMM: 313-352/352
Sequence Identity: 20% (8 aa)

IPQVLSQEVTELLR----VMIHPDPERRPSAMELVKHSVL
||. .|.|. ....     |.  .|. |... .. .|  .
IPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase Wee1.AA Pkinase_Tyr 550-568 47 3.385307 1.29 Pfam 254-270 (270) Show / Hide 
Range on Protein: 550-568
Range on HMM: 254-270/270
Sequence Identity: 47% (9 aa)

HPDPERRPSAMELVKHSVL
|.|||.||.  |.  |. |
HYDPEDRPTFSEI--HEQL