Gene AurB (Mouse)

AurB

Species: Mouse
Alias: Stk12, AurB
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: Other
Family: Aur

Sequence

Name Sequence Type Origin Length Description Download
AurB.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 251 Kinase domain by global Sugen HMM Fasta, JSON
AurB.NA RNA Sugen 1874 None Fasta, JSON
AurB.AA Protein Sugen 345 None Fasta, JSON

Protein domain

Protein domains of AurB.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AurB.AA Aur 82-332 64 3.8e-241 644.6 In-house 1-257 (257) Show / Hide 
Range on Protein: 82-332
Range on HMM: 1-257/257
Sequence Identity: 64% (167 aa)

FEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQLRREIEIQAHLKHPNILQLYNYFYDQQRIYLILEYAPRGELYKELQKS--RTFDE
||||.||||||||||||||.||. ||.|||..||.||.|...||||||||.|| ||.|||||..|.||.|.|||||||||||.|||||||||.  . |||
FEIGKPLGKGKFGNVYLARHKKTHFIFALKVMFKEQIKKYCMEHQLRREIKIQSHLNHPNILKMYGYFHDDQRIYLILEYAPGGELYKELQKQPNKRFDE

QRTATIMEELSDALTYCHKKKVIHRDIKPENLLLG-LQGELKIADFGWSVHAP-SLRRKTMCGTLDYLPPEMIEGRMHNEMVDLWCIGVLCYELMVGNPP
||.|..| .. .||.|||.|..|||||||||.||. ..|..||.|||||||.| . ||.|.||||||.||||.||.||...||.||.||||||| .| ||
QRAAKYMYQICNALDYCHSKNIIHRDIKPENILLDQCNGNIKICDFGWSVHCPNNNRRMTFCGTLDYMPPEMVEGQMHDHKVDIWCLGVLCYELCHGCPP

FES-PSHSETYRRIV-KVDLKFPSSVPSGAQDLISKLLKHNPWQRLPLAEVAAHPWV
|||  .|.|||.||  |||..|||... .|.|||||.|.|.| ||..|... .|||.
FESNENHDETYDRIKNKVDIQFPSHISKEAKDLISKILQHDPKQRMTLDQIMNHPWI
Kinase AurB.AA AGC 82-332 24 2.4e-104 270.14 In-house 1-395 (395) Show / Hide 
Range on Protein: 82-332
Range on HMM: 1-395/395
Sequence Identity: 24% (97 aa)

FEIGRPLGKGKFGNVYLAREK------KSRFIVALKILFKSQ---IEKEGVEHQLRRE------------IEIQAHLK----------HPNILQ-LYNYF
||. ...||| || |||.|.|       .  . |.|.| |.    | |.  ...  .|             .| ....          ||.| . |.  |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

YDQQR--IYLILEYAP---------RG-ELYKELQ---KSRTFDEQRTATIMEE-------LSDALTYCHK-KKVIHRD-IKPENLLLGLQGELKIADFG
 |...  .|...||.|          | ||.  ||   |...|||.|.  .. |       .  || | |. ...|||| .||||.||  .| .|..|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

WSVHAPSL----------------------------------------------------RRKTMCG--TLDYLPPEMIEGRMHNEMVDLWC--IGVLCY
 .   ..                                                     | .|.||  | .|..||..    ..  .| |.   |.| |
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

ELMVGNPPFESPS----------HSETYRRIV------KVDLKFP----------SSVPSGAQDLISKLLKHNPWQRLP----------LAEVAAHPWV
|...| ||| . .          . |.. .|       . ..|||          ... . |.|||.|||. .| .||             |. .||| 
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase AurB.AA S_TKc 82-332 32 1.6e-96 327.87 SMART 1-231 (231) Show / Hide 
Range on Protein: 82-332
Range on HMM: 1-231/231
Sequence Identity: 32% (88 aa)

FEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQLRREIEIQAHLKHPNILQLYNYFYDQQRIYLILEYAPR--GELYKELQKSRT---
.||.|..||| || ||..|.||.  |||.||.            ..||||.|  . .|||| .|| .|.| ...|...||..   |.|.. ..| ..   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FDEQRTATIMEELSDALTYCHKKKVIHRDIKPENLLLGLQGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHNE-MVDLWCIGVLCYELM
   |.| ... .| .. .|| |||....||||.||||.||    ..||.||| . .      .|.|||..|..||..    ..   .| | .|.. ||..
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

VGNPPFESPSHSETYRRIVKVDLKFPSSVPSGAQDLISKLLKHNPWQRLPLAEVAA-------HPWV
.| |||.   . .....|.          .. | |.|.|.|. .| .|.   |. .       |||.
CGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AurB.AA CAMK 87-332 20 1.2e-90 292.23 In-house 1-425 (425) Show / Hide 
Range on Protein: 87-332
Range on HMM: 1-425/425
Sequence Identity: 20% (87 aa)

PLGKGKFGNVYLAREKKSR------------FIVALKILFKSQIEK-------------------------EGVEHQLRREIEIQAH-------LKHPNI
 ||.| || |.|...|..               || ||. |... .                         .  ....||||||  .       |.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LQLYNYFYD-------------------QQRIYLIL---EYAPRGEL----YKELQKS---------------RTFDEQRTATIMEELSDALTYCHKKKV
..|| .. |                   ....|...   ||.. |||    .  ...                . |.|. .....  . .|. |||....
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDIKPENLLLGLQ-----------------GELKIADFGWSVHAPSLR-------------------------RKTMCGTLDYLP-PEMIEG------
.|||.||||.||                    . .||.||| . . ..                            ||.|||. | . ||...|      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------RMHNEMVDLWCIGVLCYELMVGNPPFESP-------------SHSETYRRIVKVDLKFPSSVPSG------------------------AQD
        . ... .| | .||..| . .| |||...             . .|....| | .  ||..  |.                        ..|
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LISKLLKHNPWQRLPLAEVAAHPWV
||.|.|. .|..|. .... .|||.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase AurB.AA CAMKL 82-332 30 5.8e-84 267.81 In-house 1-297 (297) Show / Hide 
Range on Protein: 82-332
Range on HMM: 1-297/297
Sequence Identity: 30% (91 aa)

FEIGRPLGKGKFGNVYLARE-KKSRFIVALKILFKSQIEKEGVEHQ------------LRREIEIQAHLK---HPNILQLYNYFYDQQR------IYLIL
..||. |||| || | ||.  .  .  || ||. |. | .. . ..            .||||.|. .|.   |||| .||  .....       |||..
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYAPRGE--LYKELQKS----RTFDEQRTATIMEELSDALTYCHKKKVIHRDIKPENLLLGLQG--ELKIADFGWS-----V-HAPSLRRKTMCGTLDYL
||.. ||  |.  ..|     . ..|  .  .   . .|. |||.....||||||||.||  .|   .||.||| |     .   |    || ||.. | 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

PPEMIEG--RMHN-EMVDLWCIGVLCYELMVGNPPFESPS-------HSETYRRIVKVDLKFPS---SVPSGAQDLISKLLKHNPWQRLPLAEVAAHPWV
.||...|  . ..   || | .||. | ...|. ||. ..       .  ......... ..|    .|.  ..|||.|.|..||..|  . ..  |||.
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase AurB.AA Pkinase 82-332 29 1.1e-83 289.06 Pfam 1-293 (293) Show / Hide 
Range on Protein: 82-332
Range on HMM: 1-293/293
Sequence Identity: 29% (88 aa)

FEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQLR-REIEIQAHLKHPNILQLYNYFYDQQRIYLILEYAPRG----ELYKELQ--KS
..|||..|.| || ||....|... |||.||. |. ....  .. .| .||.| ..|.||||..|| .|.| ..||...||.. |    .|.  ..  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RTF--DEQRTATIMEELSDALTYCHKKKVIHRDIKPENLLLGLQGEL----KIADFGWSV---HAPSLRRKTMCGTLDYLPPEMIE-GRMHNEMVDLWCI
..|  .|.    .| ..  .| |||....||||.||||.|.  .|..    ||.||| .    . ..   .| |||..|..|| |  |...   || | .
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVLCYELMVGNPPFESP------SHSETYRRIVKVDLKFPSSVP---------------------SGAQDLISKLLKHNPWQRLPLAEVAAHPWV
|...||.. |.||| .       .. . ..|| . .|.|... .                     . ..|.|...|. .| .|.  ...  |||.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase AurB.AA MARK 82-332 34 6.7e-78 254.24 In-house 1-262 (262) Show / Hide 
Range on Protein: 82-332
Range on HMM: 1-262/262
Sequence Identity: 34% (90 aa)

FEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQLRREIEIQAHLKHPNILQLYNYFY--DQQR-IYLILEYAPRGELYKELQKS--RT
..... .|.| .. |.||. |...  ||.||. | .. .      ..|||||  .|.|||| .|. ..   . |. ||||.|||..||||  ...   . 
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

FDEQRTATIMEELSDALTYCHKKKVIHRDIKPENLLLGLQG--ELKIADFGWSVHAPSLR-RKTMCGTLDYLPPEMIEGRMHN-EMVDLWCIGVLCYELM
  |  . .|   .  |. |||.| ..||||||||.|.  .|    ||.|||.|.. |. .  .| |||. | .||.....  .   || |  ||. | . 
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

VGNPPFESPS--HSETYRRIVKVDLKFPSSVPSGAQDLISKLLKHNPWQRLPLAEVAAHPWV
.|. ||.  .    | |..|.. . ..|. |. ....||..||..||..|  . |.  |||.
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase AurB.AA Ciliate-E2 82-332 24 3.7e-76 259.34 In-house 1-365 (365) Show / Hide 
Range on Protein: 82-332
Range on HMM: 1-365/365
Sequence Identity: 24% (91 aa)

FEIGRPLGKGKFGNVYLAREKKSR-----------------------FIVALKILFKSQIEKEGVEHQLRREIE----------IQAHLKHPNILQLYNY
... . .|.| || ||... .| .                       .|.|.||. |.|||    | .. |||.          |. .|.||||...| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FY--DQQRIYLILEYAPRGELYKELQKSRT-----------FDEQRTATIMEELSD---------------ALTYCHKKK-VIHRDIKPENLLLGLQGEL
|.  |.. |||..||.  |.|.. ......           |.|.  ..||... .               || |.|.|. .|||||||||.|.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KIADFGWSVHAPSLRR---------------------------------KTMCGTLDYLPPEMIEGRM---------HNEMVDLWCIGVLCYELMVGNPP
||.||| |  .   .                                  .| |||. |..||...|           .....|.|..||. ||.. |.||
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FESPSHSETYRRIVKVDLKFP------------------SSVPSGAQDLISK----LLKHNPWQRLP-LAEVAAHPWV
|        .. | . ...||                   ...  ..|||.|    .|. .| .|.    ..  ||| 
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase AurB.AA PLK 82-332 34 6.1e-74 240.2 In-house 1-258 (258) Show / Hide 
Range on Protein: 82-332
Range on HMM: 1-258/258
Sequence Identity: 34% (90 aa)

FEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQLRREIEIQAHLKHPNILQLYNYFYDQQRIYLILEYAPRGELYKELQKSR--TFDE
.|.|..|||| |  .| ... ... ..| |.  || ..|..    ...||||.  |.||||......| |.. .|. |||.....|  .. | |  .. |
YERGHFLGKGGFAKCYEMTDIHTKQVYAIKVVPKSLMQKPHQREKMKQEIEIHRQLHHPNIVKFHHFFEDHENVYIVLEYCHNRSLM-HYHKRRAKRLTE

QRTATIMEELSDALTYCHKKKVIHRDIKPENLLLGLQGELKIADFGWSVHAPSL--RRKTMCGTLDYLPPEMIEGRM--HNEMVDLWCIGVLCYELMVGN
  .  .|  .  .| | |....||||.|. ||.|    ..||.||| ..       |.||||||  |  ||  .|    |   || | .|.  | | .| 
PEVRYYMYQIVQGLKYLHQHRIIHRDLKLGNLFLNDNMHVKIGDFGLATRLEYDGERKKTMCGTPNYIAPEVLDGNKQGHSYEVDCWSLGCIMYTLLIGK

PPFESPSHSETYRRIVKVDLKFPSS--VPSGAQDLISKLLKHNPWQRLPLAEVAAHPWV
||||. .  |||.||.. .  ||..  .   |.||| |.|. || .|. . ..  ||. 
PPFETKDVKETYKRIKHNHYSFPEHCPISDEAKDLIQKMLNWNPDERPTIDQILQHPFF
Kinase AurB.AA RSK 85-332 32 2.1e-72 246.84 In-house 1-278 (278) Show / Hide 
Range on Protein: 85-332
Range on HMM: 1-278/278
Sequence Identity: 32% (89 aa)

GRPLGKGKFGNVYLAREK---KSRFIVALKILFKSQIEKEGV-EHQLRREIEIQAHLK-HPNILQLYNYFYDQQRIYLILEYAPRGELYKELQKSRT---
 . ||.| .| |.| |..   ... | | |.| |. | .  .     ..|..| .. . ||.| .|.  | ... .|||.|| . |||.. ||| ..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FDEQRTATIMEELSDALTYCHKKKVIHRDIKPENLLLGL---QGELKIADFGWSVH-APS--LRRKTMCGTLDYLPPEMIE---GRM-HNEMVDLWCIGV
|.| . . .| |.. |. . |....||||.|||| |.     .|..|. ||| .    ..   . .| |.|..|..|||.    ..  |.. .|.|  ||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LCYELMVGNPPFES---PSHSETYRRIVKVD--LKFP--SSVPSGAQDLISKLLKHNPWQRLP-----LAEVAAHPWV
| ||. .|.||| .    ...|. .|| | .  |..|  ...   |.|||.|.|. .| .||      ..|. .||| 
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase AurB.AA CAMK-Unique 82-332 22 2.9e-71 234.47 In-house 1-363 (363) Show / Hide 
Range on Protein: 82-332
Range on HMM: 1-363/363
Sequence Identity: 22% (81 aa)

FEIGRPLGKGKFGNVYLAREKKSRFIVALKILFK--SQIEKEGV---------------EHQLRREIEIQAHLKHPNILQLYNY----FYDQQ-------
 . .|..|.| || || .  .. . . | |.. |   ...|  .               . .|.||..|   ..||||..|| .    | | .       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------RIYLILEYAPRGELYKELQK--------------------SRTFDE--QRTATIMEELSDALTYCHKKKVIHRDIKPENLLLGLQGE-----
        ..|...||.. |.|....||                     . | |    |..|| .|  |. | |.....|||.|.||...   .      
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

-----------LKIADFGWSVHAPSLRRK----TMCGTLDYLPP--------------EMIEGRMHNEMV----DLWCIGVLCYELMVGNPPFESPSHS-
           .|..||| ..|  . .      |||||..|. |              |.|...   . .    |.| .||. |.. .|.|||....   
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR

-------ETYRRIVKVDL-KFPSSVPSG-------AQDLISKLLKHNPWQRLPLAEVAAHPWV
       |....| | |. .|.... .|       | |.. ....  | .|....|   |.|.
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase AurB.AA AktR 82-332 34 1.1e-69 237.88 In-house 1-268 (268) Show / Hide 
Range on Protein: 82-332
Range on HMM: 1-268/268
Sequence Identity: 34% (94 aa)

FEIGRPLGKGKFGNVYLAREK-KSRFIVALKILFKSQIEKEGVEHQLRREIEIQA-HLKHPNILQLYNYFYDQQRIYLILEYAPRGELYKELQKSRTFDE
|.. ..||||.||.|||...| ..  ..|.|.. |. |...  .|....|  | . . .|| | .|.  | ..  ...|.|| |.|||.  |.|...|.|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

QRTATIMEE--LSDALTYCHKK-KVIHRDIKPENLLLGLQGELKIADFGWSV----HAPSLRRKTMCGTLDYLPPEMIEG-RMHNEMVDLWCIGVLCYEL
...  .. .  |  || | |.. ..| ||.||||.||.. | .||.||| |      . . . .. |||  |..||||     || .||.|..|.. ||.
EQARFYFAQILL--ALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEM

MVGNPPFESPSHSETYRRIVKVD-LKFPSS--VPSGAQDLIS-KLLKHNPWQRLP-----LAEVAAHPWV
..|.|||.. .. . . .| . . .||| .  . | ..|||  |||. || .||        |.  ||| 
VTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase AurB.AA Pkinase_Tyr 82-225 29 5e-22 75.24 Pfam 1-156 (270) Show / Hide 
Range on Protein: 82-225
Range on HMM: 1-156/270
Sequence Identity: 29% (47 aa)

FEIGRPLGKGKFGNVYLAREK----KSRFIVALKILFKSQIEKEG-VEHQLRREIEIQAHL-KHPNILQLYNYFY-DQQR--IYLILEYAPRGELYKELQ
 ..|. ||.| ||.||... |    . .  || |.| | .  .|      . ||..|  .| .||||..||   . ...   ||...||.| | |.. |.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

K----SRTFDEQRTATIMEELSDALTYCHKKKVIHRDIKPENLLLGLQGELKIADFG
|     . .. ..   .  . .... | . |. ||||.   | |.. ..  ||.|||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase AurB.AA TyrKc 82-332 23 1.1e-16 47.24 SMART 1-280 (280) Show / Hide 
Range on Protein: 82-332
Range on HMM: 1-280/280
Sequence Identity: 23% (67 aa)

FEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQLRREIEIQAHL--KHPNILQLYNYFYDQ-------QRIYLILEYAPRGELYKELQ
 . |. || | || ||... |     || | | ..       .  ..||..|  .|  .||||..|| .  .|       . .....||.| | | . |.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KSRT-FDEQRTATIMEELSDALTYCHKKKVIHRDIKPENLLLGLQGELKIADFGWSVHAPSL-------RRKTM----CGT----LDYLPPEMIEGRMHN
|.|  .  .    ..   ..   | |.|..||||.   | |.| ..  ||.||| |    .          ...    .|     .  ..|| |  .. .
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

EMVDLWCIGVLCYELM-VGNPPFES-----PSHSETYRRIVKV-DLKFPSS--------VPSGAQDLISKLLKHNPWQRLPLAEVAAHPWV
.  | |  ||...|..  | .| .       | .| .... .   .. | .         |.   .....  ...| .|   .|.  |   
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF