Gene bsk (Fruit Fly)

bsk

Species: Fruit Fly
Alias: D-junk, Junk, DJNK, SAPKa, DJNK/bsk, D-JNK, Jun N-terminal kinase, bsk, JNK, JNK/SAPK, dJNK, CG5680, SFO101
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 31B3,

Classification

Group: CMGC
Family: MAPK
Subfamily: JNK

Sequence

Name Sequence Type Origin Length Description Download
bsk.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 297 Kinase domain by global Sugen HMM Fasta, JSON
bsk.AA Protein Various 372 None Fasta, JSON

Protein domain

Protein domains of bsk.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase bsk.AA JNK 24-320 68 1.1e-243 815.86 In-house 1-309 (309) Show / Hide 
Range on Protein: 24-320
Range on HMM: 1-309/309
Sequence Identity: 68% (212 aa)

YINLRPIGSGAQGIVCAAYDTITQQNVAIKKLSRP--FQNVTHAKRAYREFKLMKLVNHKNIIGLLNAFTPQRNLEEFQDVYLVMELMDANLCQVIQ---
|.||..||.|||||||.|.|..|.|.|||||..||  |||..|.|||||||..||..||||||...|.||||..||||||||.|||.||.||||||.   
YQNLKFIGQGAQGIVCMAFDQVTNQRVAIKKMMRPDNFQNWMHWKRAYREFICMKCINHKNIIKMYNCFTPQETLEEFQDVYIVMEYMDWNLCQVIHSTF

MDLDHDRMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKADCTLKILDFGLARTAGTTFMMTPYVVTRYYRAPEVILGMG--YTENVDIWSVGCIMGEM
|.|||.|||||.|||.||||||||.||||||||||||||..||||||.|||.|||...|||||||||||||||||||.||.  |.||||||||||||.||
MELDHERMSYLFYQMCCGIKHLHSMGIIHRDLKPSNIVVNQDCTLKICDFGHARTEDPTFMMTPYVVTRYYRAPEVICGMMDNYKENVDIWSVGCIMAEM

IRGGVLFPGTDHIDQWNKIIEQLGTPSPSFMQRLQPTVRNYVENR---PRYTGYSFDRLFPDGLFP--NDNNQNSRRKASDARNLLSKMLVIDPEQRISV
||. |||||.|||||||||||.||||.|.||...||.||||||||   |.|..|.|...||| |||  .............||.||..||||.|..||||
IRHHVLFPGKDHIDQWNKIIEFLGTPDPHFMMQMQPHVRNYVENRNMDPYYQPYNFHEHFPDTLFPDVMQSEPKDHLTCHMARDLLFRMLVINPDDRISV

DEALKHEYI
|.||.|.||
DDALQHPYI
Kinase bsk.AA MAPK 24-320 47 9.1e-191 640.05 In-house 1-328 (328) Show / Hide 
Range on Protein: 24-320
Range on HMM: 1-328/328
Sequence Identity: 47% (159 aa)

YINLRPIGSGAQGIVCAAYDTITQQN------VAIKKLSRPFQNVTHAKRAYREFKLMKLV-NHKNIIGLLNAFTP-----QRNLEEFQDVYLVMELMDA
| .|.|||.||.|.||.|.|. |.|.      |||||.||||||.||.||.||| ||..   .|.|||.||. |||     |..||||.|.|.|||||..
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

NLCQVIQ-MD-LDHDRMSYLLYQMLCG--IKHLHSAGIIHRDLKPSNIVVKADCTLKILDFGLARTAGTT---------------FMMTPYVVTRYYRAP
.|.|.|. .. |..|...|..||.|.|  .|..|||..||||||||||.|  .|.|||.||||||.. ..               ..||.||.||.||||
DLHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAP

EVILG---MGYTENVDIWSVGCIMGEMIR-GGVLFPGTDHIDQWNKIIEQLGTPSPSFMQRLQ-P-TVRNYVENR---PRYTGYSFDRLFPDGLFPNDNN
|..|.   |.||..||.||||||..||.. . .||||.|.|||||.|.|.|||||. |.|... .  .|||....   |.|...... .||. .|     
EIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANF-----

QNSRRKASDARNLLSKMLVIDPEQRISVDEALKHEYI
    .. ..|..||.||||.||..||.|.||| |.|.
----NANPQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase bsk.AA p38 24-320 49 3.2e-141 475.47 In-house 1-289 (289) Show / Hide 
Range on Protein: 24-320
Range on HMM: 1-289/289
Sequence Identity: 49% (150 aa)

YINLRPIGSGAQGIVCAAYDTITQQN---VAIKKLSRPFQNVTHAKRAYREFKLMKLVNHKNIIGLLNAFTP-QRNLEEFQDVYLVMELMDANLCQVIQM
| ||.|.|||| | ||.|.|. |.|    ||||||.|||| . ||||.||| .| |. .| |.|.||. |||  .....|||||.|...|.| | ... .
YQNLQPVGSGAYGQVCKAEDRRTGQKRRYVAIKKLMRPFQSEIHAKRTYRELRLLKHMRHENVICLLDVFTPPAHSMNDFQDVYMVTHFMGADLNNIMKC

D-LDHDRMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKADCTLKILDFGLARTAGTTFMMTPYVVTRYYRAPEVILG-MGYTENVDIWSVGCIMGEMI
  |  |.  .|.||.| | |  ||||||||||||||| |  || |.||||||||   .   || ||.|| |||||..|  | ||. |||||||||| |.|
QRLSDDHIQFLVYQILRGLKYIHSAGIIHRDLKPSNIAVNEDCELRILDFGLAR--HCDDEMTGYVATRWYRAPEIMLNWMHYTQTVDIWSVGCIMAELI

RGGVLFPGTDHIDQWNKIIEQLGTPSPSFMQRLQPTV-RNYVENRPRYTGYSFDRLFPDGLFPNDNNQNSRRKASDARNLLSKMLVIDPEQRISVDEALK
 | .||||.||||| ..|.. .|||.. |.|..|    |||....| ..   | ..|             ..    | .|| |||..||..||.. ||..
TGRTLFPGDDHIDQLQRIMKVCGTPDEEFWQKIQSEEARNYIQSYPQMPRRDFHHVF-------------MGANPQAIDLLEKMLELDPDKRITAEEAMQ

HEYI
|.|.
HPYF
Kinase bsk.AA CMGC 24-320 26 1e-135 448.88 In-house 1-513 (513) Show / Hide 
Range on Protein: 24-320
Range on HMM: 1-513/513
Sequence Identity: 26% (135 aa)

YINLRPIGSGAQGIVCAAYDTITQQN--------------VAIKKLSRPFQNVTHAK----------RAYREFKLMKLVN-----------------HKN
| ....||.|. |.|. ..|. |.|.              |||||...|| . ..||          ||.|| |..| .|                 |.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IIGLLNAFTPQ---RNLEE--------FQDVYLVMELMDANLCQVIQM-----------DLDHDR------------MSYLL------YQMLCGIK--HL
|..|.. |..    .|..|        |...|||.|.|| .|.|.|..            |..                |..      ||.|.|.|  ..
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HSAG--IIHRDLKPSNIVVKADCTL--------------------KILDFGLARTAGT----------------------TFMMTPYVVTRYYRAPEVIL
||..  ||||||||.|| .  .|.|                    || ||||||  ..                      . ..|.|||||.|||||..|
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

G----------MGYTENVDIWSVGCIMGEMIRG--------GVLFP-----------GTDHIDQWNKIIEQLGTP----------------SPSFMQRLQ
|          |.||. .|.||||||..||..|          |||           |..||||..||.. ||||                .  ......
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

---------------------PTVRNYVEN---RPRYTGYSFDRLFPDGLFPNDNNQNS------------------------RRKASDARNLLSKMLVI
                     . .|||...    |.. . .. .|||.  ...| | |                         ..  ..|..||.|||..
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDD-N-NKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQY

DPEQRISVDEALKHEYI
||..||....||.|.|.
DPDKRITAEQALQHPYF
Kinase bsk.AA ERK 24-320 40 5.4e-110 371.73 In-house 1-307 (307) Show / Hide 
Range on Protein: 24-320
Range on HMM: 1-307/307
Sequence Identity: 40% (129 aa)

YINLRPIGSGAQGIVCAAYDTI-----TQQNVAIKKLSRPFQNVTHAKRAYREFKLMKLVN-HKNIIGLLNAFTP-QRNLEEFQDVYLVMELMDANLCQV
|  . .|| || |.||.| |.      |.| ||||| ...| .   .||..|| ||... . |.|||.|.. . | ...  .. |.|.| |||.  | |.
YQIIKQIGHGAYGVVCSAIDKEYCFDETGQKVAIKKIENAFDHPIYCKRTLREIKLLRHFKGHENIICLFDIMMPNSPE--QYNDIYCVEELMETDLHQI

IQMD--LDHDRMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKADCTLKILDFGLAR---------TAGTTFMMTPYVVTRYYRAPEVILGM-GYTENV
|. .  |  |   |..||.|||.|..|||..|||||||||| |  .|.||| ||||||         . ..  .|| ||.||.|||||..|    ||. .
INSQQELSDDHCQYFMYQILCGLKYIHSANVIHRDLKPSNILVNSNCDLKICDFGLARCFDASYQENHECNQNFMTEYVATRWYRAPEIMLSWQKYTKAM

DIWSVGCIMGEMIRGGVLFPGTDHIDQWNKIIEQLGTP-SPSFMQRL-QPTVRNYVENRPR--YTGYSFDRLFPDGLFPNDNNQNSRRKASDARNLLSKM
||||.|||. ||...  |||| |...| | |.. .||| |   .|.   . ...|. | |   ... ..  .||.               ..| .||.||
DIWSCGCIFAEMLGRKPLFPGKDYVHQINRIFQIIGTPHSEEDLQYICSENAWKYIKNLPNPVRPPKPWENIFPNAN-----------CNPQAIDLLEKM

LVIDPEQRISVDEALKHEYI
||.||..||.|.|.|.|.| 
LVFDPDKRITVEECLEHPYF
Kinase bsk.AA S_TKc 24-320 27 2.9e-92 313.73 SMART 1-231 (231) Show / Hide 
Range on Protein: 24-320
Range on HMM: 1-231/231
Sequence Identity: 27% (86 aa)

YINLRPIGSGAQGIVCAAYDTITQQNVAIKKLSRPFQNVTHAKRAYREFKLMKLVNHKNIIGLLNAFTPQRNLEEFQDVYLVMELMDA---NLCQVIQMD
|  ||.||.|| | |. .... |.. ||||...         ....|| ...|  .|.||. |. .|         ...|.|||..|    .| ..|.  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYIKKR

--------LDHDRMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKADCTLKILDFGLARTAGTTFMMTPYVVTRYYRAPEVILGMGYTE-NVDIWSVGC
        ..  .  ...||..|.....|| |||||||||.|| .    ..|| ||||||        | ...|..|.||||.   ||.   .|.||.||
GRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC

IMGEMIRGGVLFPGTDHIDQWNKIIEQLGTPSPSFMQRLQPTVRNYVENRPRYTGYSFDRLFPDGLFPNDNNQNSRRKASDARNLLSKMLVIDPEQRISV
|. ||. |  .||      | .......|                                                  ..|.....|.|. |||.|...
ILYEMLCGYPPFP------QMQMMFKKIG-------------------------------------------------SPEAKDFIRKCLQKDPEKRPTA

DEALK-------HEYI
 |||.       |...
-EALQDEWDIKCHPWF
Kinase bsk.AA ERK5 24-320 39 3.4e-87 295.98 In-house 1-295 (295) Show / Hide 
Range on Protein: 24-320
Range on HMM: 1-295/295
Sequence Identity: 39% (121 aa)

YINLRPIGSGAQGIVCAAYDTITQQNVAIKKLSRPFQNVTHAKRAYREFKLMKLVNHKNIIGLLNAFTPQRNLEEFQDVYLVMELMDANLCQVIQMD--L
|  .  || || |.||.|    . | |||||.   |  || ||| .|| |...   | ||| . .   |.  . |..||| |..||.. | |.|  .  .
YKIIEKIGNGAYGVVCSARRRKNGQQVAIKKIPNAFDVVTNAKRTFRELKILRHFRHDNIIAIRDILMPKVPYSEMKDVYVVFDLMESDLHQIIHSNQPF

DHDRMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKADCTLKILDFGLARTAGT------TFMMTPYVVTRYYRAPEVILGM-GYTENVDIWSVGCIMG
  . . | |||.| |.| .||| .|||||||||..|   | ||| |||.||   |       . || || ||.|||||... .  ||  .|.||||||.|
TLEHIRYFLYQILRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTFSPDKHQMFMTEYVATRWYRAPELMFSSHDYTQAIDVWSVGCIFG

EMIRGGVLFPGTDHIDQWNKIIEQLGTPSPSFMQRLQP-TVRNYVEN-RPRYTGYSFDRLFPDGLFPNDNNQNSRRKASDARNLLSKMLVIDPEQRISVD
|||    .|||   |.| . |.. ||.|.|  .|      |.||.    |  .   .....|             .    | .||..||. .| .||.| 
EMIARRQMFPGKNYIHQLQLIMMVLGMPPPHMIQAVSADHVYNYFQKNFPNRQPKDWEKVYP-------------KADRQALDLLARMLRFEPSERITVN

EALKHEYI
.||.| ..
KALQHPFL
Kinase bsk.AA nmo 28-320 39 6.6e-84 257.82 In-house 5-292 (292) Show / Hide 
Range on Protein: 28-320
Range on HMM: 5-292/292
Sequence Identity: 39% (117 aa)

RPIGSGAQGIVCAAYDTITQQNVAIKKLSRPFQNVTHAKRAYREFKLMKLVNHKNIIGLLNAFTPQRNLEEFQDVYLVMELMDANLCQVI--QMDLDHDR
|||| || |.| .  |    . ||.||.   |||.  .|| .|| |..   .| |.. .|.   |  ... ||..| | ||| . | ..|     |  | 
RPIGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVLSALDILQPP-HKDFFQEIYVVTELMQSDLHKIIVSPQHLSSDH

MSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKADCTLKILDFGLART--AGTTFMMTPYVVTRYYRAPEVILGM-GYTENVDIWSVGCIMGEMIRGGVL
.   |||.| |.| ||||.|.|||.|| |..| ..| ||| ||||||.    .   ||  ||| ||||||...|   ||. ||||||||| .|..   .|
VKVFLYQILRGLKYLHSANILHRDIKPGNLLVNSNCVLKICDFGLARVWEQDQSKHMTQEVVTQYYRAPEILMGARHYTSAVDIWSVGCIFAELLGRRIL

FPGTDHIDQWNKIIEQLGTPSPSFMQRLQPTVRNYVENRPRYTGYSFDRLFPDGLFPNDNNQNSRRKASDARNLLSKMLVIDPEQRISVDEALKHEYI
|     |.| . |.. |||||   |.      .. .  .|     ....|.  .|   |       .. .| .||..||. ||..|||. .||.| |.
FQAQSPIQQLQMITDLLGTPSMEDMKYACEGAKAHMLRMPHKPP-CLQVLY--TLSSPD------HATHEAVHLLCRMLHFDPDKRISCKDALAHPYL
Kinase bsk.AA ERK1 24-320 43 5.2e-83 282.08 In-house 1-289 (289) Show / Hide 
Range on Protein: 24-320
Range on HMM: 1-289/289
Sequence Identity: 43% (132 aa)

YINLRPIGSGAQGIVCAAYDTITQQNVAIKKLSRPFQNVTHAKRAYREFKLMKLVNHKNIIGLLNAFTPQRNLEEFQDVYLVMELMDANLCQVIQM-DLD
|.||. || || |.||.||||...| |||||.| ||   |. .|  || |...  .| |||.. .       .|...|||.| .||.  | ....   | 
YTNLQYIGEGAYGMVCSAYDTVHKQRVAIKKIS-PFEHQTYCQRTLREIKILTRFKHENIINIQDIIR-ADTIEQMRDVYIVQCLMETDLYKLLKTQHLS

HDRMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKADCTLKILDFGLARTAGT----TFMMTPYVVTRYYRAPEVIL-GMGYTENVDIWSVGCIMGEMI
 | . | |||.| |.| .||| ..||||||||...   | ||| |||||| |      |  .| || ||.|||||..|   |||  .||||||||. ||.
NDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEML

RGGVLFPGTDHIDQWNKIIEQLGTPSPSFMQR-LQPTVRNYVENRPRYTGYSFDRLFPDGLFPNDNNQNSRRKASDARNLLSKMLVIDPEQRISVDEALK
    .|||   .|| |.|.  || ||   ..  .    |||..  |  .  ...||||          ..  || |   || |||   |..|| |.||| 
SNRPIFPGKHYLDQLNHILGVLGSPSQDDLNCIINEKARNYLQSLPHKPKVPWARLFP----------KADSKALD---LLDKMLTFNPHKRITVEEALA

HEYI
| |.
HPYL
Kinase bsk.AA ERK7 24-320 37 2e-81 276.79 In-house 1-292 (292) Show / Hide 
Range on Protein: 24-320
Range on HMM: 1-292/292
Sequence Identity: 37% (116 aa)

YINLRPIGSGAQGIVCAAYDTITQQNVAIKKLSRPFQNVTHAKRAYREFKLMKLVN-HKNIIGLLNAFTPQRNLEEFQDVYLVMELMDANLCQVIQ-MDL
|  .. .| || |||  |||  |.| ||.||    |.| | | | .||  ...  . | ||| |.| .  . ..    |.||| | |.. |  ||.  ..
YEIRKRLGKGAYGIVWKAYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVIRADNDR----DIYLVFEFMETDLHAVIRKGNI

DHD-RMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKADCTLKILDFGLARTAGTTF-------MMTPYVVTRYYRAPEVILG-MGYTENVDIWSVGCI
  |    | .||.|  ||..||. .|||||||||| . ..|..|. ||||||. . .        |.| || || |||||. ||   ||  || ||.|||
LKDIHKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECMVKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGCI

MGEMIRGGVLFPGTDHIDQWNKIIEQLGTPSPSFMQRLQPTVRNYV-ENRPRYTGYSFDRLFPDGLFPNDNNQNSRRKASDARNLLSKMLVIDPEQRISV
.|||.||  .||||  ..| .||.| .. |.   .. ... ..  . |. ..   ...| ..|.                || .|| ..||  |..|...
LGEMLRGKPMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMNQQKRKTLDQMMPQC-------------CDDAIDLLKRLLVFNPKKRLTA

DEALKHEYI
..||.| |.
EQALQHPYV
Kinase bsk.AA Pkinase 24-320 27 4.1e-78 270.6 Pfam 1-293 (293) Show / Hide 
Range on Protein: 24-320
Range on HMM: 1-293/293
Sequence Identity: 27% (87 aa)

YINLRPIGSGAQGIVCAAYDTITQQNVAIKKLSRPFQNVTHAKRAYR--EFKLMKLVNHKNIIGLLNAFTPQRNLEEFQDVYLVMELMDA-----NLCQV
|  .|.||||. | |. ...  |.. ||.|..... ..    ... |  | ..|| .||.||. |. .|.        ...|.|||...       |. .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED------KDHIYMVMEYCEGGLYVMDLFDY

IQ-------MDLDHDRMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKADCTL----KILDFGLART--AGTTFMMTPYVVTRYYRAPEVIL-GMGYTE
|.       . .. .     .||.|.|....|| |||||||||.|| .. ....    || |||||.         || ...|..|.|||||. | .|. 
ISTWRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGP

NVDIWSVGCIMGEMIRGGVLFPGT----DHIDQWNKIIEQLGTPSPSFMQRLQPTVRNYVENRPRYTGYSFDRLFPDGLFPNDNNQNSRRKASDARNLLS
 ||.||.|||. ||. |  .|||     . .|| ...|.. . | ..|      .....  .. . .                .  .  .  .... ...
KVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQ-MQMICRIMGPPLHFDWPWWCSISYFFFRH-W-H--------------F-HWTF-HNWSEECKDFIK

KMLVIDPEQRISVDEALKHEYI
..|  ||..|.. ...|.|...
WCLCKDPKKRPTAEQILQHPWF
Kinase bsk.AA MAPK-Unclassified 24-172 43 2.6e-55 190.05 In-house 1-157 (575) Show / Hide 
Range on Protein: 24-172
Range on HMM: 1-157/575
Sequence Identity: 43% (68 aa)

YINLRPIGSGAQGIVCAAYDTIT-QQNVAIKKLSRPFQNVTHAKRAYREFKLMKLVNHKNIIGLLNAFTPQRNLE-EFQDVYLVMELMDA---NLCQVIQ
|     ||||| |.|| | |. .  | |||||. . |.|.| .||. ||  .    || ||| . . |..   .  ||.|.|.||..|     .| |.|.
YEYQKNIGSGAYGQVCRAMDKKNQNQQVAIKKVNHIFHNHTDCKRVLREIRILRYLNHPNIIQIQDIFYNKELHNQEFDDIYIVMDYMQTSLFDLHQIIK

MDL---DHDRMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKADCTLKILDFGLAR
 ..    |    |..|| | |.| ||||.||||||||||. .  ||...| |||..|
SNQDHWCHQHIQYFFYQILRGLKYLHSACIIHRDLKPSNLLINQDCSVRICDFGMSR
Kinase bsk.AA MAPK-Unclassified 180-320 31 5.5e-38 132.52 In-house 405-575 (575) Show / Hide 
Range on Protein: 180-320
Range on HMM: 405-575/575
Sequence Identity: 31% (55 aa)

MTPYVVTRYYRAPEVILGMG-YTENVDIWSVGCIMGEMIRG-----------GVLFPGTD--------------------HIDQWNKIIEQLGTPSPSFM
|| |||||.||||| .| |. |.  |||||.||| .||.             . ||||.|                    |.|| . |.. ||.|    .
MTQYVVTRWYRAPEIMLSMHEYDTQVDIWSIGCIFAEMMQMYDRHNPTFSDHRPLFPGQDCFPITPDRNNDVDQGGFPHSHQDQIKMIFDYLGMPPEEDC

QRLQ-PTVRNYVENRPRYTGYSFDRLFPDGLFPNDN-NQNSRRKASDARNLLSKMLVIDPEQRISVDEALKHEYI
.. . . .| |..   . | . |. |.    |..   .    |   .......|||...|  ||. |.||.|.|.
NFITCDSARKYIQSFKCKTPVHFTDLM----FCKAPGDDQIVRGNCECIDFVQKMLQFNPWKRITADQALEHPYF
Kinase bsk.AA TyrKc 24-320 21 3.9e-15 21.93 SMART 1-280 (280) Show / Hide 
Range on Protein: 24-320
Range on HMM: 1-280/280
Sequence Identity: 21% (72 aa)

YINLRPIGSGAQGIVCAAYDTITQQNVAIKKLSRPFQNVTHAKRAYREFKLMKLV--NHKNIIGLLNAFTPQ-RNLEEF---QDVYLVMELMDA-NLCQV
   .. .|.|| |.|. .  .   ..||.|.|          .  .|| ..|. .  .|.||. |. . | | ||   |   . ...|||.|.  .| . 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN---FMYIEPLMIVMEYMPHGDLKDY

I-QMD--LDHDRMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKADCTLKILDFGLARTAGTT---------FMM-----TPYVVTRYYRAPEVILGMG
.      | .. . .  .|  ||  .||| ..|||||   |. |... | || ||||.|  .            ..     . ...     |||.|    
LRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

YTENVDIWSVGCIMGEMI-RGGVLFPG-----TDHIDQWNKIIEQLGTPSPSF---MQRLQPTVRNYVENRPRYTGYSFDRLFPDGLFPNDNNQNSRRKA
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FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS-------------------------------------FVCCP

SDARNLLSKMLVIDPEQRISVDEALKHEYI
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DEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase bsk.AA Pkinase_Tyr 24-173 28 9e-07 23.56 Pfam 1-160 (270) Show / Hide 
Range on Protein: 24-173
Range on HMM: 1-160/270
Sequence Identity: 28% (48 aa)

YINLRPIGSGAQGIVCAAYDT----ITQQNVAIKKLSRPFQNVTHA----KRAYREFKLMKLV-NHKNIIGLLNAFT-PQR-NLEEFQDVYLVMELMDA-
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ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE--GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN-----QIYIVMEYMPHG

NLCQVIQMD------LDHDRMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKADCTLKILDFGLART
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DLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARD
Kinase bsk.AA Pkinase_Tyr 191-208 44 0.602102 3.83 Pfam 182-199 (270) Show / Hide 
Range on Protein: 191-208
Range on HMM: 182-199/270
Sequence Identity: 44% (8 aa)

APEVILGMGYTENVDIWS
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APECINYGKFTTKSDVWS