Gene cdc2c (Fruit Fly)

cdc2c

Species: Fruit Fly
Alias: CDK2/CDC2c, DmCdk2, CDC2c, S(Sev-CycE)3A, CG10498, Cdc2c, Dcdc2c, Cdk2, CDK2, SFO163, Dmcdc2c, DmCdc2, cdk2, cdc2c
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 92F10,

Classification

Group: CMGC
Family: CDK
Subfamily: CDK2

Sequence

Name Sequence Type Origin Length Description Download
cdc2c.AA Protein Various 314 None Fasta, JSON
cdc2c.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 280 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of cdc2c.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase cdc2c.AA CDC2 8-287 61 4.3e-222 690.15 In-house 1-301 (301) Show / Hide 
Range on Protein: 8-287
Range on HMM: 1-301/301
Sequence Identity: 61% (186 aa)

FQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEG--VPSTAIREISLLKNLK-HPNVVQLFDVVISGNNLYMIFEYLNMDLKKLMD---KKKDV
.|. |||||||||.|||.. . |.| ||||||||| |.||  ||||||||||.||.|| |||.|.|.||... |.|||.||||.|||||.||   .|...
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNKH

FTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQNLLVDTAGKIKLADFGLARAFNVPMRAYT--HEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFSEM
..|||.||||.|||..| |||..||.||||||||.|.|..|.||.|||||||||..|.|.||  |||||||||||||||| |.|||.||.||.||||.||
MPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEM

---IMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTKFPRWEGTNMPQPITE-----------HEAHELIMSMLCYDPNLRISAKDALQHA
   .... ||.||||||||..|||.| ||.| .|||||||||.|..||||. ... . .             .|...|.|.||.|||. |||||.|||| 
FMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQHP

YF
||
YF
Kinase cdc2c.AA CDK 8-287 52 5.3e-183 590.52 In-house 1-284 (284) Show / Hide 
Range on Protein: 8-287
Range on HMM: 1-284/284
Sequence Identity: 52% (166 aa)

FQRAEKIGEGTYGIVYKARSNSTG-----QDVALKKIRLEG-----ETEGVPSTAIREISLLKNLKHPNVVQLFDVVISG-----------NNLYMIFEY
... |||||||||.|||||.  ||     | |||||||.|      | ||.|.||||||||||.| |||.|.|.||...            |.|||.|||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

LNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQNLLVDTAGK-----IKLADFGLARAFNV------PMRAYTHEVVTLWYRAPE
. .||||.||          ||.||.|.|... .|| |.|.||||||||.|..  |.     .|.|||||||||..      |.|.||||||||||||||
MDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPE

ILLGTKFYS--TGVDIWSLGCIFSEMIM---RRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTKFPRWEGTNMPQPITEHEAHELIMSMLCY
.|||.| ||  |..|.||.||||.||..   |. ||||||||||| .|||.. ||.| ||||||.|||.                      .|...||||
LLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY----------------------DLLNKMLCY

DPNLRISAKDALQHAYF
||. ||||..|||| ||
DPKKRISAEQALQHPYF
Kinase cdc2c.AA CDK5 8-287 53 8.49999999999e-160 508.97 In-house 1-287 (287) Show / Hide 
Range on Protein: 8-287
Range on HMM: 1-287/287
Sequence Identity: 53% (153 aa)

FQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQLFDVVISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLI
... |||||||||.|||||   |.  ||||..||. | |||||||||||.||| |||.|.| |.||. | . | ..||..  |||| ||. ..   ...|
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEKKLTLVFEFCDQDLKKYMDSCNGEMDMHII

KSYMHQILDAVGFCHTNRILHRDLKPQNLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFSEMI-MRRSLF
||.| | |  ..||| ...|||||||||||. . |. ||||||||||| .| | |.|||||||||.| .|.| | ||| .|.|| |||| ||.   | ||
KSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAGRPLF

PGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFK---TKFPRWEGTNMPQPIT---EHEAHELIMSMLCYDPNLRISAKDALQHAYF
|| .. ||| |||. . || | .||..|.|||.|   ...| ....   |.|.   . .  .|   || ..|| |||||.||.|.||
PGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase cdc2c.AA CDK7 8-287 42 5.5e-147 394.71 In-house 1-288 (288) Show / Hide 
Range on Protein: 8-287
Range on HMM: 1-288/288
Sequence Identity: 42% (124 aa)

FQRAEKIGEGTYGIVYKARSNSTGQDVALKKIR----LEGETEGVPSTAIREISLLKNLKHPNVVQLFDVVISGNNLYMIFEYLNMDLKKLMDKKKDVFT
..  ..||||... ||||.  .||| || |||.     .    |.  |||||| .|. ..|.||. | |.     |....|...  ||      |. ..|
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKSNIQLVFDFMDWDLEVVIKDKSIILT

PQLIKSYMHQILDAVGFCHTNRILHRDLKPQNLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFSEMIMRR
|  ||.|| ..|  . .|| | |||||||| |||..  |..|.|||||||..  | |.||| ||| |||||| | | . | ||||.|| |||| | . | 
PAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELMLRV

SLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTKFPRWEG---TNMPQPIT--EHEAHELIMSMLCYDPNLRISAKDALQHAYF
  .||||.|||| |||.|| || | .||......|.  ||  . |   | . .  |    .. .|.  |.  .|  |... ..|.. ||
PYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDY-IKFKDFPGYSRTPLRHIFTAASDDLLDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase cdc2c.AA CMGC 8-287 26 2.1e-143 474.6 In-house 1-513 (513) Show / Hide 
Range on Protein: 8-287
Range on HMM: 1-513/513
Sequence Identity: 26% (136 aa)

FQRAEKIGEGTYGIVYKARS--------------NSTGQDVALKKIR----LEG-----ETEGVPSTAIREISLLKNLK-----------------HPNV
..  .||||||||.|||.|               . |.. ||.|||.     |.     | .|.|..|.|||..||.|.                 |.|.
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VQLFDVVISGN-----------------NLYMIFEYLNMDLKKLMDKKKD--------VFTPQL------------IKSYM------HQILDAVG--FCH
|.|.|.. . |                 .||..|||. .||.........         ...              ||..|      .||| ..   .||
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

TNR--ILHRDLKPQNLLVDTA--------------------GKIKLADFGLARAFNVP---------------------MRAYTHEVVTLWYRAPEILLG
 ..  |.||||||.|.|..                      |..|..||||||.....                     .|.|||.|||.||||||||||
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

TKFYS---------TGVDIWSLGCIFSEMIMR--------RSLFPGDSE-----------IDQLYRIFRTLSTPD---------------ETNWPGVTQL
 | |.         |..|.||.|||| ||...        . ||||.||           ||||..||..| ||.               | .||....|
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKL

PDFKT--------------------------KFPRWEG---TNMPQPITE----------------------------------HEAHELIMSMLCYDPN
|....                          .||.| .   .|.  .. .                                  ..| .|.. ||.|||.
PWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPD

LRISAKDALQHAYF
 ||.|..|||| ||
KRITAEQALQHPYF
Kinase cdc2c.AA PITSLRE 8-287 45 1.1e-120 407.29 In-house 1-295 (295) Show / Hide 
Range on Protein: 8-287
Range on HMM: 1-295/295
Sequence Identity: 45% (135 aa)

FQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLE--GETEGVPSTAIREIS-LLKNLKHPNVVQLFDVVI--SGNNLYMIFEYLNMDLKKLMDKKK---
||   .|.|||||.||.|.   |.  ||||.. .|   | || | |..|||. .|. |.|||.|..  .|.   ..  ||..||.  ||| ||.. |   
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVNVKEIVMGSNMDKIYMVMEYVEHDLKSLMENMKRRN

DVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQNLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFSEM
. |.|  ||. | | | .| . | | |.|||||  |||   .|  |..|||||| .  |...||  ||||||||||.|||.| ||| ||.|| |||| |.
QPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGCIFAEF

IMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFK-TK-FPRWEGTNMPQPIT-----EHEAHELIMSMLCYDPNLRISAKDALQHAYF
|. . ||.|.|||||. .||  . || |  |||.| || .| .. ||     |  . .         . .|   ||.|.|  ||.| |||.| .|
ITMKPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNNFPHYPYNNLRKRFPAENHISDTGFDLLNQMLTYNPKNRITASDALKHPWF
Kinase cdc2c.AA PFTAIRE 8-287 47 1.6e-116 393.42 In-house 1-287 (287) Show / Hide 
Range on Protein: 8-287
Range on HMM: 1-287/287
Sequence Identity: 47% (139 aa)

FQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQLFDVVISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLI
... || |||.|  |||..|  ..| |||| |||. | ||.| ||||| |||||||| |.| | |..     | ..|||.. ||.. |||      |. .
YEKLEKLGEGSYATVYKGISCINQQFVALKEIRLQQE-EGTPFTAIREASLLKNLKHANIVCLHDIIHTKETLTFVFEYVHTDLCQYMDKHPGGMHPNNV

KSYMHQILDAVGFCHTNRILHRDLKPQNLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFSEMIMRRSLFP
. .. | |    .||  |.|||||||||||.  .|  ||||||||||  || . | ||||||||| | .|||   ||| .|.|  |||| ||.  . .||
RLFLFQLLRGLSYCHQRRVLHRDLKPQNLLISHCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTHLDMWGVGCIFVEMMWGQPAFP

GD-SEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTKFPRWEG--TNMPQPITE--------HEAHELIMSMLCYDPNLRISAKDALQHAYF
|     ||| .||..| || |  ||||..|| .|   | | .     |..  .         .| .|.| || . |  |.||..|.|| ||
GMKDITDQLEKIFKVLGTPTEDTWPGVCHLPNYK---PHWFRGRFYKPKKLCHQWPRIYYIPHAEDLMMKMLQCEPRDRVSAQEAMQHPYF
Kinase cdc2c.AA PCTAIRE 8-287 47 7e-114 384.63 In-house 1-291 (291) Show / Hide 
Range on Protein: 8-287
Range on HMM: 1-291/291
Sequence Identity: 47% (140 aa)

FQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQLFDVVISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLI
. . .| |||||  ||| ||  |.  |||| |||| | || | |||||.||||.||| |.| | |..     | ..|||..||||. ||    .     .
YIKLDKLGEGTYATVYKCRSKLTDNLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVTLHDIIHTHHQLTLVFEYMDMDLKQYMDDCGNIMNMHNV

KSYMHQILDAVGFCHTNRILHRDLKPQNLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFSEMIMRRSLFP
| .. |.|    .||  .||||||||||||..  |  ||||||||||  || . | ||||||||| |..|.|   ||| .|.|  |||| ||   | |||
KLFLFQLLRGLAYCHRRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSHEVVTLWYRPPDVLMGSTDYSTQIDMWGVGCIFYEMCTGRPLFP

GDS------EIDQLYRIFRTLSTPDETNWPGVTQLPDFKT-KFPRWEGTNM--PQPITE---HEAHELIMSMLCYDPNLRISAKDALQHAYF
|          |||  ||| | ||||  ||||. ...|.|  |||.    .    |  .    .  .|. ..| | .  |.|| .|..| ||
GSTDSHYPGVKDQLHMIFRILGTPDEKTWPGVKSNEEFRTYNFPRYREQPLINHAPRLDKILKQCQDLLTMLLQYESKNRVSAEKAMKHPYF
Kinase cdc2c.AA CRK7 8-287 34 4.5e-107 362.01 In-house 1-343 (343) Show / Hide 
Range on Protein: 8-287
Range on HMM: 1-343/343
Sequence Identity: 34% (120 aa)

FQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGE---TEGVPSTAIREISLLKNLKHPNVVQLFDVVISG----------NNLYMIFEYLNMDLKKL
... . ||||||| ||||. ..||. |||||.|...|    || | |||||| .|. |.|.|.|.| ..|..            . ||.|||   ||  |
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQLNHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDLMGL

MDKKKDV-FTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQNLLVDTAGKIKLADFGLARAFNVPM--RAYTHEVVTLWYRAPEILLGTKFY--------
.. |  . | .| .|..| |.|. .  || . .||||.|  |.|..  |..|.||||||| .|     | ||  |.|||||.|| |||.. |        
LESKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHILKE

------------------------------STGVDIWSLGCIFSEMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKT-----KFPRWEG
                               . .|.|| |||. |   .. .|.|  |..||  |..   .|   ||| |..|| ..|     .. |   
LIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNPNNWPEVMKLPWWNTMKPKRQYNRRLR

TNMPQ----PITEHEAHELIMSMLCYDPNLRISAKDALQHAYF
 .  .     .   |.  |   |||.||  |..|...||| .|
EEFYHHKKPVFMPKECLDLLDKMLCLDPKKRFTAEECLQHDWF
Kinase cdc2c.AA CDK4 8-287 45 8.99999999999e-105 354.37 In-house 1-290 (290) Show / Hide 
Range on Protein: 8-287
Range on HMM: 1-290/290
Sequence Identity: 45% (135 aa)

FQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETE--GVPSTAIREISLLKNLK---HPNVVQLFDV--VISGNN----LYMIFEYLNMDLKKLMD
.| .  |||| ||.||.||.  ||..||||..|   . |  |.|   |||||... |.   |||.|.|.||  |.        . |.||    ||. ..|
YQCVAEIGEGAYGTVYRARDLHTGHFVALKQVRIPIGEEGGGMPMSTIREISVMRHLCQFEHPNIVKLMDVCHVMDTDRAEMKITMVFEHCDWDLHTYLD

KKKD-VFTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQNLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCI
|       |. ||  |||.| .| | |..|| ||||||||.||   |..||||||||| .   | | |  ||||||||||.||    | | ||.||.|||
KCPPPGMPPCTIKHMMHQLLRGVDFLHSHRIIHRDLKPQNILVTSDGHVKLADFGLARIYSFQM-ALTPVVVTLWYRAPEVLL-QSYYNTPVDMWSVGCI

FSEMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTKFPRWEGTNMPQ--PITEHEAHELIMSMLCYDPNLRISAKDALQHAYF
|.||  || ||.| || ||| .||    .| |  ||    ||     ||    ...    |  .  . .|.  ||||.. .|.||  .||| ||
FAEMYCRRPLFCGQSEKDQLHKIFDVMGLPPEDDWPRDVSLP--WDHFPQRHPRPFKDFCPHMCKQGDDLLQKMLCYNHHKRMSAYQCLQHPYF
Kinase cdc2c.AA S_TKc 8-287 31 2e-104 354.11 SMART 1-231 (231) Show / Hide 
Range on Protein: 8-287
Range on HMM: 1-231/231
Sequence Identity: 31% (93 aa)

FQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQLFDVVISGNNLYMIFEYLNM---DLKKLMDKKKDV---
..  .|||.|..| |||.| ..||. ||.|.|.          ...|||..||. .|||.|.|.||  . ..|||..||..    ||.....|..     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--FTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQNLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYST-GVDIWSLGCIFSE
  |..  ...||.||..|. .|| ..|.||||||.|.|.|.   ||..|||||| .       |. ..|.||.|||.|     |..  .|.||.|||. |
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYE

MIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTKFPRWEGTNMPQPITEHEAHELIMSMLCYDPNLRISAKDALQ-------HAYF
|. .. .||   ........ .                                     .|| ..|. .|..||. |..| .|||       | .|
MLCGYPPFP---QMQMMFKKIG------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase cdc2c.AA Pkinase 8-287 34 4.7e-102 350.15 Pfam 1-293 (293) Show / Hide 
Range on Protein: 8-287
Range on HMM: 1-293/293
Sequence Identity: 34% (103 aa)

FQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIR--EISLLKNLKHPNVVQLFDVVISGNNLYMIFEYLNM-----DLKKLMD-KKK
... .|||.|..| |||..  .||. ||.|.|....| .... |..|  ||...|.|.|||.|.|.|.. .....||..||...     ||. ..  ...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

DVF--TPQLIKSYMHQILDAVGFCHTNRILHRDLKPQNLLVDTAGKI----KLADFGLARAF-NVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSL
 .|  ... .|.|| ||| .. .|| ..|.||||||.|.|.|  | |    |..|||||. | . . . .|. ..|.||.|||...| . |.. ||.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GCIFSEMIMRRSLFPGD----SEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTKFPRWEGTNMPQPITEHEAHELIMSMLCYDPNLRISAKDALQHAYF
|||. ||. .| .|||.    . .||...|.|....| . .||     ..|.... . .  ... . .. |. ..| ..||.||. |..|...||| .|
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRH-W-HF-HWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase cdc2c.AA Pkinase_Tyr 8-154 29 1.2e-23 80.67 Pfam 1-160 (270) Show / Hide 
Range on Protein: 8-154
Range on HMM: 1-160/270
Sequence Identity: 29% (49 aa)

FQRAEKIGEGTYGIVYKARSN----STGQDVALKKIRLEGETEGVPSTA------IREISLLKNL-KHPNVVQLFDVVI-SGNN--LYMIFEYLNM-DLK
 .  .|.||| .| |||.. .    .|...|| |...     ||  . .      .||....|.| .|||.|.|  |..  |    .|...||    ||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK-----EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLL

KLMDKK---KDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQNLLVDTAGKIKLADFGLARA
.   |.   |. .|.. . .. .|| ..  . . ... ||||   | ||.  ...| .||||||.
DYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARD
Kinase cdc2c.AA TyrKc 8-285 19 2.1e-15 26.47 SMART 1-280 (280) Show / Hide 
Range on Protein: 8-285
Range on HMM: 1-280/280
Sequence Identity: 19% (62 aa)

FQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNL--KHPNVVQLFDVVISG-------NNLYMIFEYLNM-DLKKLMDK
 .  .|.||| .|.|||.. .   ..|| |... .          .||......|  .|||.|.|. |....         |....||    |||.   |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

KKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQNLLVDTAGKIKLADFGLARAFNVP------MRAYT-----HEV--VTLWYRAPEILLGTKFYS
... ....   |...|| .   . | ... ||||   | ||.  . .| .||||.|.             |.     ..   . .   ||| .  .. ..
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFT

TGVDIWSLGCIFSEMIMR-RSLFPG-------DSEIDQLYRIFRTLSTPDE----TNWPGVTQLPDFKTKFPRWEGTNMPQPITEHEAHELIMSMLCYDP
|  |.|| |    |.  .  .  ||       ..|. .. .  . .  |..                              ..   | .... .   .||
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS----------------------F--VCCPDEMYQIMKQCWHEDP

NLRISAKDALQHA
. | . ..  .  
EDRPTFSEIHECF