GL50803_90343

Species: G.lamblia
Alias: GL50803_90343, GK075
External Links: GiardiaDB ,
Annotation:

Classification

Group: Other
Family: WNK

Sequence

Name Sequence Type Origin Length Description Download
GL50803_90343.AA Protein None 568 None Fasta, JSON
GL50803_90343.kin_dom Protein Kinase Domain None 257 None Fasta, JSON

Protein domain

Protein domains of GL50803_90343.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase GL50803_90343.AA WNK 47-306 45 1.8e-98 318.72 In-house 1-261 (261) Show / Hide
Range on Protein: 47-306
Range on HMM: 1-261/261
Sequence Identity: 45% (120 aa)

LKYSGDVLGKGAFKTVYRAFDLIAGREVAWNEVVLDTLEPMASSKLFQEIKALKDVDHENIIKLYDHW---FEGSNLLIFTTELMPSGCLKKYLKKNPTA
.|.  . .|.|.||||||..|   . ||||.|. .  |.      .  |.  ||.  | ||...|| |     |    .  |||| || || |||     
MKFDEE-VGRGSFKTVYRGLDTETWVEVAWCELQDQKLSKNERQRFKEEAEMLKKLQHPNIVRFYDYWESVLCGKKCIVLVTELMTSGTLKTYLKRFKKM

LTTPVLKSWALQILEALNYMHTCQP-KIIHRDIKAQNIFINGATGVVKVGDLGLCASLGLQSTAVSCIGTPEFMAPETYSNAHYDEKVDIYAFGMLLLEL
    ||.||  |||  |...||.||  |||||.|  ||||.| || ||.|||||  .|  .| | | |||||||||| |   |||| ||.||||| .|| 
KPK-VLRSWCRQILKGLHFLHTRQPHPIIHRDLKCDNIFITGTTGSVKIGDLGLAVTLKNSSFAKSVIGTPEFMAPEMY-EEHYDESVDVYAFGMCMLEM

ITRDTPYLECANIVDVLKKVEGNIPPNGLNKVVHKEMKDLILLCINKDPSARPSARELLSKPFL
 | ..|| || |   . .||   | || ..|.   | |..|. || .. . |||...||.  |.
ATSEYPYSECQNAAQIYRKVTQGIKPNSFQKIQNPEVKEIIEKCIRHNKEERPSIQQLLNHDFF

Kinase GL50803_90343.AA S_TKc 48-306 28 1.6e-65 224.87 SMART 1-231 (231) Show / Hide
Range on Protein: 48-306
Range on HMM: 1-231/231
Sequence Identity: 28% (78 aa)

KYSGDVLGKGAFKTVYRAFDLIAGREVAWNEVVLDTLEPMASSKLFQEIKALKDVDHENIIKLYDHWFEGSNLLIFTTELMPS--GCLKKYLKKNPTA--
   ....||||| .||.. .   ||.||  ..           .. .||. ||  .|.||.||||.. .  . | . .|...   | |..|.||...   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LTTPVLKSWALQILEALNYMHTCQPKIIHRDIKAQNIFINGATGVVKVGDLGLCASLGLQSTAVSCIGTPEFMAPETYSNAHYDE-KVDIYAFGMLL
   ..  . .... ||..||.|.|    .|||||.| .||...    ..|..| ||.. |       ...|||..||||     .|.  |.|....| .|
RFPFPE-HARFYMYQICCALEYCHSH--GIIHRDLKPENILLDE---HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

LELITRDTPYLECANIVDVLKKVEGNIPPNGLNKVVHKEMKDLILLCINKDPSARPSARELLS-------KPFL
 |.... .|.    ..  ..||.              .|.||.|  | .|||. ||.| |.|         |..
YEMLCGYPPFP---QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase GL50803_90343.AA STE 49-306 24 3.9e-58 199.44 In-house 1-359 (359) Show / Hide
Range on Protein: 49-306
Range on HMM: 1-359/359
Sequence Identity: 24% (89 aa)

YSG-DVLGKGAFKTVYRAFDL------IAGRE---------VAWNEVVLDTLEP---------------MASSKLFQEIKALKDVD--HENIIKLYDHWF
. | ...||||| |||.| .         |..         .|  .. |.. ..               .   .. .||| .|. .  |.||.| |.. |
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

EG-------SNLLIFTTELMPSGCLKKYLKKNPTALTT-------------PVLKSWALQILEA-LNYMHTCQPKIIHRDIKAQNIFINGATGVVKVGDL
 .       ..| |.  |.|. |.| . .|..   . .             ....  . |||.. |.| |  .  |||||||..||..      ||  | 
KEGHNHKNDDELWIC-MEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH--IIHRDIKPANILL------VKLCDF

GLCASLGL-----------------QSTAVSCIGTPEFMAPETYSN------AHYDEKVDIYAFGMLLLELITRDTPYLECANI---------------V
|.|..|                   |.   ...||| .||||  ..       .||.|.||. .| ...|..|   |. .  .                .
GVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQF

DVLKKVEGNIP--PNGLN---------------KVVHKEMKDLILLCINKDPSARPSARELLS--KPFL
..|. |.|..|  |. |                . . .|.|| | .| .|||. ||.| .||.   ||.
EQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI

Kinase GL50803_90343.AA Pkinase 51-306 25 2.8e-56 198.07 Pfam 4-293 (293) Show / Hide
Range on Protein: 51-306
Range on HMM: 4-293/293
Sequence Identity: 25% (75 aa)

GDVLGKGAFKTVYRAFDLIAGREVAWNEVVLDTLEPMASSKLFQ--EIKALKDVDHENIIKLYDHWFEGSNLLIFTTELMPSG----CLKKYLK-KNPTA
| ..|.|.| .||.. .   |..||  .. ... ..     ..   ||. .| ..|.||..||| . .....  . .|... |     |. |.. .. ..
GRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIY-MVMEYCEGGLYVMDLFDYISTWRHGC

L--TTPVLKSWALQILEALNYMHTCQPKIIHRDIKAQNIFINGATGVV----KVGDLGLCAS--LGLQSTAVSCIGTPEFMAPETYS-NAHYDEKVDIYA
.  .  ..|....|||..|.|.| .  .|||||.| .||.|.  .|..    |..| ||..   .  .| . .  |||..||||    . .|. |||...
FYFSEWECKFYMYQILRGLEYCHSM--GIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

FGMLLLELITRDTPYLEC---ANIVDVLKKVEGNIP-PNGLNKVVH---------------------KEMKDLILLCINKDPSARPSARELLSKPFL
.| .| |.... .|. ..    | .| ..... . . |.  .                         .|.||.|  |..|||. ||.|...|  |..
CGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase GL50803_90343.AA TKL 54-304 21 1.3e-49 171.1 In-house 1-364 (364) Show / Hide
Range on Protein: 54-304
Range on HMM: 1-364/364
Sequence Identity: 21% (79 aa)

LGKGAFKTVYRA-FDLIA-------GREVAWNEVVLDTL----------------------EPMASSKLFQEIKALK---DVDHENIIKLYD------H-
.|.|.| .||.. .  .        |..||      .                        .|.||   |.|.. ..     .|.||....       . 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-WFE----GSNLLIFTTELMPSGC-LKKYLKKNPTALTTPVLKSWALQILEALNYMHTCQ------PKIIHRDIKAQNIFING-------------ATGV
 . .    ... | . .|..| |. |  ..         ... .|||.|  ..||.|...      |.|||||.| .||...              |...
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

VKVGDLGLCASLGLQS--------------------TAVSCIGTPEFMAPETYSNA----------------HYDEKVDIYAFGMLLLELITRDTPYLEC
.|..|.||. ..   .                    |  ...||| .||||   ..                 |.||.|.|.||..| |..|| .|| . 
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDY

AN-------------IVDVLKKVEGNIPPNGLN-------KVVHKEMKDLILLCINKDPSARPSARELLSKP
 .             .....|.    |||  .|       . . ..||.|.  | . ||..|||. |.|.. 
PYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase GL50803_90343.AA Ciliate-E2 48-306 19 1.6e-47 161.19 In-house 1-365 (365) Show / Hide
Range on Protein: 48-306
Range on HMM: 1-365/365
Sequence Identity: 19% (74 aa)

KYSGDVLGKGAFKTVYRAFDLIAGR------------------EVAWNEVVLDTLEPMASSKLFQEIKALK----------------DVDHENIIKLYDH
     ..|.|.| .||.. .   ..                  .|. ... . ....     ..|||. ..                 ..| ||||.|..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

WFE-GSNLLIFTTELMPSGCLKKYLKKNPT----------ALTTPVLKSWALQILE---------------ALNYMHTCQPKIIHRDIKAQNIFINGATG
. |   | . . .|.   | |..|.|.|..           .|    |    |||.               ||.|.|   . ||||||| .||..     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNN-IIHRDIKPENILF-----

VVKVGDLGLCASLGLQ--------------------------------STAVSCIGTPEFMAPETYSNAH---------YDEKVDIYAFGMLLLELITRD
 .|. |.||.  .  .                                 .. ...|||..|||| ...           ||.|.||...|..| |...  
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

TPYLECANIVDVLKKVEGNIPPNGLN---------------KVVHKEMKDLILL----CINKDPSARPS-ARELLSKPFL
.|.          .. ...|  .  .               | . .|.||||      ...|||. |.. . ..|  |..
PPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase GL50803_90343.AA Ciliate-E2-Unclassified 99-306 19 8.4e-43 146.29 In-house 71-352 (352) Show / Hide
Range on Protein: 99-306
Range on HMM: 71-352/352
Sequence Identity: 19% (56 aa)

LKD--VDHENIIKLYDHWFEG-SNLLIFTTELMPSGCLKKYLKKNPT----------------ALTTPVLK-----SWALQILEALNYMHTCQPKIIHRD
...  ..| ......... .   . ... .|... | |..|.||...                 .|    |      .. |||..|.|.|  . .|||||
MQQILLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKN-NIIHRD

IKAQNIFINGATG--VVKVGDLGLCASLGL----------------QSTAVSCIGTPEFM----APETYSNAHYD----EKVDIYAFGMLLLELITRDTP
|| .||...   .   .|. |.|..  ..                 |  . ...|||..|    ||| . . .||    .|.||...|..| |...   |
IKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYP

YL--ECAN-------------IVDVLKKV-EGNIPPNGLNK-----VVHKEMKDLIL----LCINKDPSARPSARELLSKPFL
.    |               .  ....  ..||  .  ..      ...| ||.|      ...|.|. |... ..|  |..
FYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase GL50803_90343.AA CAMK 53-306 16 1.8e-41 130.96 In-house 1-425 (425) Show / Hide
Range on Protein: 53-306
Range on HMM: 1-425/425
Sequence Identity: 16% (71 aa)

VLGKGAFKTVYRAFDLIAG------------REVAWNEVVLDTLE--------------------------PMASSKLFQEIKALKD-------VDHENI
.||.|.| .|.....   .            ..||   .  . |                           |    ....||. .|        .||.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKLYDHWF------------EGSN--------LLIFT--TELMPSGCL----KKYLKKNPT--------------ALTTPVLKSWALQILEALNYMHTCQ
||||...               |.        . ...  .|... |.|      |.....                .|    . .  ||..|..|.| . 
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

PKIIHRDIKAQNIFINGAT----------------GVVKVGDLGLCASLGL------------------------QSTAVSCIGTPEFMA-PETYSN---
  |.|||.|  || ..                   . .|. | |. . .                                . ||||.|| ||  .    
--IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGH

-----------AHYDEKVDIYAFGMLLLELITRDTPYLECA------------NIVDVLKKVE-GNI--PPNG--------------------LNKVVHK
             |..|.|. . | .|  . .   |. .              |. . ..|.  |.   ||                       .  | .
CNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHH-FVSQ

EMKDLILLCINKDPSARPSARELLSKPFL
| ||||  . ..||. |... . |. |..
ECKDLIRKMLQVDPEKRMTIEQCLNHPWM

Kinase GL50803_90343.AA PEK 148-306 21 8.7e-39 132.31 In-house 428-655 (655) Show / Hide
Range on Protein: 148-306
Range on HMM: 428-655/655
Sequence Identity: 21% (50 aa)

VLKSWALQILEALNYMHTCQPKIIHRDIKAQNIFINGATG----VVKVGDLGLCAS----------------------LGLQSTAVSC------------
...... ||||.|||.| ..  .||||.|..|||.         .||.|| ||. .                      .  .... .             
QCWRIFRQILEGLNYIHSQG--MIHRDLKPSNIFLDCDGQHHQMQVKIGDFGLATNHEMLSQSQKNYNQQDQSYWKYVANDNCQWWNTNQQNSPTGQDTH

------------------------IGTPEFMAPETYSNA-----HYDEKVDIYAFGMLLLELITR-DTPYLECANIVDVLKKVEGNIPPNGLN---KVVH
                        .||. .|.|| .|.      ||..|||.|. | ...|.. .  |.  |.... . |...  ..|    .    . .
MWSNNYHIQPTSMFYCEHCHHTGGVGTCLYMSPEQLSGQHYQKSHYNHKVDMYSLGIIFFEMWYPFFTTMMERVKTLTDLRDESIQFPGDFPPKWFDNKY

KEMKDLILLCINKDPSARPSARELLSKPFL
.. .|.|......||. |||| ..|. .|.
PKQADFIQWMLSHDPQQRPSAQQILQHEFF

Kinase GL50803_90343.AA STE11 50-306 27 3.7e-38 133.08 In-house 3-303 (303) Show / Hide
Range on Protein: 50-306
Range on HMM: 3-303/303
Sequence Identity: 27% (83 aa)

SGDVLGKGAFKTVYRAFDLIAGREVAWNEVVLDTLEPM------ASSK------LFQEIKALKDVDHENIIKLYDHWF---EGSNLLIFTTELMPSGCLK
.|...||||| |||.....  |...|  .. ..  ..|        ..      . .||| .|  .|.||.. |..     . ... ||  | .| | |.
KGEIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIF-MEYCPGGSLS

KYLK-K-NPTALTTPVLKSWALQILEALNYMHTCQPKIIHRDIKAQNIFINGATGVVKVGDLGLCASLG--LQSTAV---------SCIGTPE-------
  |. |  |  .. .| .    ||||.|.| |  . .|||||||. ||...   .|.| .| | . .|   ...|.          |  |||        
SMLRHKWGPMKFDEMVIRKYTKQILEGLQYLH--SHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSMMGTP

-FMAPETYSNAH---YDEKVDIYAFGMLLLELITRDTPYLECAN--IVDVLKKVEG-NIPPNGLNKVVH-----KEMKDLILLCINKDPSARPSARELLS
 .||||....     |. |.|| ..|   .| .|   |. .. .  .    | ..| . .|.   ..        | .| ...|  .||. ||.|..|| 
MWMAPEVIKQEGRDGYGRKADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTANQLLQ

KPFL
 ||.
HPFI

Kinase GL50803_90343.AA STE-Unique 153-306 23 5.2e-35 121.54 In-house 409-616 (616) Show / Hide
Range on Protein: 153-306
Range on HMM: 409-616/616
Sequence Identity: 23% (48 aa)

ALQILEALNYMHTCQPKIIHRDIKAQNIFINGAT----GVVKVGDLGLCASLGLQ---------------------------------------STAVSC
..||||.|.| |. .  |||||.|. |||..  .      ||..| |.  ....                                        .|  .|
TYQILEGLEYLHSQHNPIIHRDLKPHNIFCMQDGKGRVCKVKICDFGHATCCQPDHFEKDNNSKNSNTWININNNSSTNSTAQQTPMWDLNINNYTMKYC

IGTPEFMAPETYSNA-----HYDEKVDIYAFGMLLLELITRDTPYLECANI------VDVLKKVEGNIPPNGLNKVVHKEMKDLILLCINKDPSARPSAR
.|||  |.||. . .     .|| ||||. .|........   |. .  ..       . ...  .. |     .   .|. ..| .|....|. |||| 
CGTPCYMCPEVINCRNQINNPYDTKVDIWSLGCMCFHMCCGCPPWHQRYHMQAYIEMCIHIHCQPPQCPIENIPPKCQPEQQQFIEKCLERNPHHRPSAH

ELLSKPFL
.|| ...|
QLLHHFWL

Kinase GL50803_90343.AA NEK 53-244 29 2.4e-31 107.88 In-house 6-219 (286) Show / Hide
Range on Protein: 53-244
Range on HMM: 6-219/286
Sequence Identity: 29% (64 aa)

VLGKGAFKTVYRAFDLIAGRE-----VAWNEVVLDTLEPMASSKLF-QEIKALKDVDHENIIKLYDHWFEG-SNLLIFTTELMP-SGCLKKY---LKKNP
..|.|.| .||.. . . |..     ..| .. .. . .    ..  .|.. ||  .|.||.| ||...|  .| |.   |     | | .    .||. 
KIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKSIKKQK

T---ALTTPVLKSWALQILEALNYMHTC---QPKIIHRDIKAQNIFING-AT--GVVKVGDLGLCASLGLQSTAVS--CIGTPEFMAPETYSNAHYDEKV
     .   .   |  |.. ||.|||     | ||.||||| ||||..   .  ..||.||.|.   |.  ... .  ..||| .|.||  .|  |..|.
QKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNKPYNNKS

DIYAFGMLLLELIT
|| ..| .| |. |
DIWSLGCVLYEMCT

Kinase GL50803_90343.AA TyrKc 51-306 24 3.4e-21 77.67 SMART 4-280 (280) Show / Hide
Range on Protein: 51-306
Range on HMM: 4-280/280
Sequence Identity: 24% (70 aa)

GDVLGKGAFKTVYRAFDLIAGREVAWNEVVLDTLEPMASSKLFQEIKALKDV--DHENIIKLYDHWFEGS------NLLIFTTELMPSGCLKKYLKKNPT
|..|| ||| .||..      ..||   .  |.        . .|.. .. .  .|.||..||    ...        |   .|.|| |.||.||.|.  
GKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

ALTTPVLKSWALQILEALNYMHTCQPKIIHRDIKAQNIFINGATGVVKVGDLGLCASLGLQ--------STAV----SCI--GTPEFMAPETYSNAHYDE
 |... | |...|| .  .| |    ..||||. | |. ..    .||..| ||.  ..             .    ..        ||||.     . .
KLCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

KVDIYAFGMLLLELITR-DTPYLEC----ANIVDVLKKVEGN----IPPNGLNKV----VHKEMKDLILLCINKDPSARPSARELLSKPFL
| |...|| .. |. |. ..|| .      .  .|...|.      .|||..  .     ..|| .... | . ||. ||. .|.  . ..
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYP-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF

Kinase GL50803_90343.AA Pkinase_Tyr 91-197 31 3.4e-18 62.26 Pfam 49-158 (270) Show / Hide
Range on Protein: 91-197
Range on HMM: 49-158/270
Sequence Identity: 31% (36 aa)

KLFQEIKALKDV-DHENIIKLYDHWF-EGSN--LLIFTTELMPSGCLKKYLKKN---PTALTTPVLKSWALQILEALNYMHTCQPKIIHRDIKAQNIFIN
....|.| .|   .|.||..||     .|    ..|  .|.|| |.|..||.|.   . .||.. | ....|| ....| .  .  .||||. | |. ..
DFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIV-MEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN--CIHRDLAARNCLVT

GATGVVKVGDLGLC
  ..|||..| ||.
E-NNVVKICDFGLA

Kinase GL50803_90343.AA NEK 277-306 36 2.6e-10 32.9 In-house 257-286 (286) Show / Hide
Range on Protein: 277-306
Range on HMM: 257-286/286
Sequence Identity: 36% (11 aa)

KEMKDLILLCINKDPSARPSARELLSKPFL
.....|| ....|||. |||....|..||.
QDLQNLISQMLQKDPEQRPSCNQILEMPFI

Kinase GL50803_90343.AA STE-Unique 49-118 22 8.1e-10 30.47 In-house 1-74 (616) Show / Hide
Range on Protein: 49-118
Range on HMM: 1-74/616
Sequence Identity: 22% (17 aa)

YSGDVLGKGAFKTVYRAFDLIAGREVAWNEVVLDTLEPMA----SSKLFQEIKALKDVDHENIIKLYDHWFEGS
   . .|.|.| .|.....   .. .| . . |... .       ...  || ..|   |.||.|.| ||..|.
NCQQMIGRGSFGNVHNCQNKKDCFRCAIKVIHLKQFKDFNQEPLVNMIISEIEIMKCLHHQNIVKYYGHWLWGG

Kinase GL50803_90343.AA Pkinase_Tyr 216-306 26 7e-06 20.62 Pfam 181-270 (270) Show / Hide
Range on Protein: 216-306
Range on HMM: 181-270/270
Sequence Identity: 26% (25 aa)

MAPETYSNAHYDEKVDIYAFGMLLLELIT-RDTP-YLECANIVDVLKKV-EGNIPPNGLNKVV--HKEMKDLILLCINKDPSARPSARELLSKPFL
||||  ..  . .| |...|| |. |..|  ..| | ..    .|.... | .     . .    ..|. ||...| ..||. ||. .|.    .|
MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGM-SNEEVYEYIYEDGYR---MPCPENCPDEIYDLMKQCWHYDPEDRPTFSEI--HEQL

Kinase GL50803_90343.AA PEK 50-108 22 8.9e-05 11.72 In-house 3-77 (655) Show / Hide
Range on Protein: 50-108
Range on HMM: 3-77/655
Sequence Identity: 22% (17 aa)

SGDVLGKGAF-KTVYRAFDLIAGREVAWNEVVLDTLEPM---------------ASSKLFQEIKALKDVDHENII
 ...||||.|   ||.. . . |.. |  ...|.  . .               .. | ..|.|.|   .|.||.
EIQCLGKGGFGGQVYKVQNKLDGCYYAIKRIKLNWKQRKQPCITQECMIHKCKKHCEKVLREVKTLARLNHPNIV