Gene GL50803_8961 (G.lamblia)
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
---|---|---|---|---|---|
GL50803_8961.AA | Protein | None | 968 | None | Fasta, JSON |
GL50803_8961.kin_dom | Protein Kinase Domain | None | 214 | None | Fasta, JSON |
Protein domains of GL50803_8961.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
---|---|---|---|---|---|---|---|---|---|
Kinase | GL50803_8961.AA | NRBP | 86-227 | 25 | 6e-06 | 16.62 | In-house | 111-261 (261) | Show / Hide |
Range on Protein: 86-227 Range on HMM: 111-261/261 Sequence Identity: 25% (39 aa) QIVDALVYLHVPFKPHGVIVNGSLSTSTVLIDQH--MNIRMLLPGMTRSQIEKWLYSDAPELVIPNRYMVHKNVYLSTKVDIWSLGKILLDLATLGTG-- ||. || ||| | |. | | . |. | . . | | .... . .. | . .. | | |||.| | |..| |. QILSALSYLHSCDPP---IIHGNLTCDTIFIQHNGLIKIGCVWPDAIHHHVRTCREEMRNMHFFAPEYGILEVTDLTTAVDIYSFGMCALEMAVLEIQSG -LSSLTK-------QPHFAAVYPQWISETIFRSLSLDPAERPSAIHLLHIPELK . .. | .. . . | . | |||.|||| .|| . | CQNGESEYVTEEAIQRAIHSLEDPMQRDFIRKCLQKDPARRPSARELLFHQILF |
|||||||||
Kinase | GL50803_8961.AA | CDK-Unclassified | 201-226 | 19 | 5.1e-05 | 12.29 | In-house | 299-324 (324) | Show / Hide |
Range on Protein: 201-226 Range on HMM: 299-324/324 Sequence Identity: 19% (5 aa) ETIFRSLSLDPAERPSAIHLLHIPEL ...| ....| .|... .|. |.. NCEFQMVMYQPYNRWKCMEILQHPWF |
|||||||||
S_TKc | GL50803_8961.AA | S_TKc | 13-226 | 15 | 0.000207 | -112.24 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 13-226 Range on HMM: 1-231/231 Sequence Identity: 15% (41 aa) EIDIEDLANDGFCTCTEEYTPD------------QPLTHKLLLECTSMHRDFTDFEDSLT-----------------LQRYLTNRRL--SREPLSADQIA .. . .| .. . . . . .|. | . |. | .|. .|. | |.. ... YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKK--HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HAR FIFEQIVDALVYLHVPF------KPHGVIVNGSLSTSTVLIDQHMNIRMLLPGMTRSQIEKWLYSDAPELVIPNRYMVHKNVYLST-KVDIWSLGKILLD |.. ||..|| |.| || . .. ..| . .. .| .. |||.. .. |.|.||.| || FYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL----TTFCGTPWYM---APEVL-----------GYGKCKCDWWSCGCILYE LAT----LGTGLSSLTKQPHFAAVYPQWISETIFRSLSLDPAERPSAIHLLH-------IPEL ... . . |. |. .. | . | ||..||.| .|. | . MLCGYPPFP-QMQMMFKKIG----SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
|||||||||
Kinase | GL50803_8961.AA | SgK071 | 160-177 | 66 | 0.00036 | 10.39 | In-house | 199-216 (283) | Show / Hide |
Range on Protein: 160-177 Range on HMM: 199-216/283 Sequence Identity: 66% (12 aa) STKVDIWSLGKILLDLAT |.| |||||| |.|| .| SQKSDIWSLGCIILDMTT |
|||||||||
Kinase | GL50803_8961.AA | Ciliate-E2-Unclassified | 59-95 | 21 | 0.000369 | 10.35 | In-house | 106-160 (352) | Show / Hide |
Range on Protein: 59-95 Range on HMM: 106-160/352 Sequence Identity: 21% (12 aa) LTLQRYLT-------------NRRLSREPLSADQIA-----FIFEQIVDALVYLH ..|. |.. .....|. .. |.. |.| ||...| ||| GDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLH |
|||||||||
Kinase | GL50803_8961.AA | NEK8 | 207-226 | 40 | 0.000839 | 6.6 | In-house | 259-278 (278) | Show / Hide |
Range on Protein: 207-226 Range on HMM: 259-278/278 Sequence Identity: 40% (8 aa) LSLDPAERPSAIHLLHIPEL |..||. |||| ... | . LQQDPEQRPSASQIMAMPLC |
|||||||||
Kinase | GL50803_8961.AA | CDK-Unclassified | 72-95 | 37 | 0.138988 | 0.82 | In-house | 115-138 (324) | Show / Hide |
Range on Protein: 72-95 Range on HMM: 115-138/324 Sequence Identity: 37% (9 aa) REPLSADQIAFIFEQIVDALVYLH | .|| || . |.. ..||| RYNLSMCQIRNFMHQMLEGIAYLH |
|||||||||
Ank | GL50803_8961.AA | Ank | 388-410 | 34 | 0.001113 | 17.53 | Pfam | 1-23 (33) | Show / Hide |
Range on Protein: 388-410 Range on HMM: 1-23/33 Sequence Identity: 34% (8 aa) NGHTALMMAAYRGYDTCVRILLN .| |.|..|...|. .|. ||. DGFTPLHLACRCGHTEVVKMLLQ |
|||||||||
Ank | GL50803_8961.AA | Ank | 417-437 | 33 | 2.919093 | 5.2 | Pfam | 1-21 (33) | Show / Hide |
Range on Protein: 417-437 Range on HMM: 1-21/33 Sequence Identity: 33% (7 aa) TESSALLLAMMSGHYKCIKLL ..| || ..||....|.| DGFTPLHLACRCGHTEVVKML |
|||||||||
Ank | GL50803_8961.AA | Ank | 444-458 | 33 | 0.243637 | 9.09 | Pfam | 1-15 (33) | Show / Hide |
Range on Protein: 444-458 Range on HMM: 1-15/33 Sequence Identity: 33% (5 aa) NGVTPLMYYASLGNV .| |||..... |.. DGFTPLHLACRCGHT |
|||||||||
Ank | GL50803_8961.AA | Ank | 480-506 | 37 | 0.018833 | 13.1 | Pfam | 1-25 (33) | Show / Hide |
Range on Protein: 480-506 Range on HMM: 1-25/33 Sequence Identity: 37% (10 aa) TGWTALMFAAAGGFTLCVNLLLADEQG |.|.|. |. | | .| .|| .| DGFTPLHLACRCGHTEVVKMLLQ--HG |
|||||||||
Ank | GL50803_8961.AA | Ank | 511-535 | 36 | 2e-06 | 27.22 | Pfam | 1-25 (33) | Show / Hide |
Range on Protein: 511-535 Range on HMM: 1-25/33 Sequence Identity: 36% (9 aa) NGETALMKAASRNNNNVIQLLLQQG .|.|.|. |..... .|...|||.| DGFTPLHLACRCGHTEVVKMLLQHG |
|||||||||
Ank | GL50803_8961.AA | Ank | 545-568 | 41 | 0.026927 | 12.54 | Pfam | 1-24 (33) | Show / Hide |
Range on Protein: 545-568 Range on HMM: 1-24/33 Sequence Identity: 41% (10 aa) DGRTALMIAVQNTALESVLLLQQH ||.|.|..|... .| | .| || DGFTPLHLACRCGHTEVVKMLLQH |
|||||||||
Ank | GL50803_8961.AA | Ank | 638-668 | 33 | 3e-05 | 23.19 | Pfam | 1-33 (33) | Show / Hide |
Range on Protein: 638-668 Range on HMM: 1-33/33 Sequence Identity: 33% (11 aa) SGATALMHAAQNGHHGCVRYLLG--KELGMQDR | |.|. |...||. .|..||. .. .||. DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD |
|||||||||
Ank | GL50803_8961.AA | Ank | 607-637 | 30 | 0.002739 | 16.12 | Pfam | 1-33 (33) | Show / Hide |
Range on Protein: 607-637 Range on HMM: 1-33/33 Sequence Identity: 30% (10 aa) FGLTALMYAAMSGYCDCVQLLAT--SEAGAQDE | |.|..|...|. ..|..| . ||| DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD |
|||||||||
Ank | GL50803_8961.AA | Ank | 669-691 | 30 | 0.033242 | 12.21 | Pfam | 1-23 (33) | Show / Hide |
Range on Protein: 669-691 Range on HMM: 1-23/33 Sequence Identity: 30% (7 aa) TGWTALMWATQGNYATCVKEILD |.|.|..| . ... .||. |. DGFTPLHLACRCGHTEVVKMLLQ |
|||||||||
Ank | GL50803_8961.AA | Ank | 576-606 | 24 | 0.243637 | 9.09 | Pfam | 1-33 (33) | Show / Hide |
Range on Protein: 576-606 Range on HMM: 1-33/33 Sequence Identity: 24% (8 aa) SGVTALMFAAQGGFAEAITILYS--TETGIKDS | |.|. |.. | .| .. | . . ..| DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD |
|||||||||
Ank | GL50803_8961.AA | Ank | 746-766 | 28 | 0.000337 | 19.4 | Pfam | 1-21 (33) | Show / Hide |
Range on Protein: 746-766 Range on HMM: 1-21/33 Sequence Identity: 28% (6 aa) NGSTALMIAAQKNHLSCAQLL .| |.|..|....|......| DGFTPLHLACRCGHTEVVKML |
|||||||||
Ank | GL50803_8961.AA | Ank | 777-799 | 30 | 0.01575 | 13.38 | Pfam | 1-23 (33) | Show / Hide |
Range on Protein: 777-799 Range on HMM: 1-23/33 Sequence Identity: 30% (7 aa) SGSTALMRAAFSGASDIALLLLE | |.|. |...| ... .||. DGFTPLHLACRCGHTEVVKMLLQ |
|||||||||
Ank | GL50803_8961.AA | Ank | 808-829 | 36 | 0.00121 | 17.4 | Pfam | 1-22 (33) | Show / Hide |
Range on Protein: 808-829 Range on HMM: 1-22/33 Sequence Identity: 36% (8 aa) DGLTALMYAAQAGMDLCVQLLI || |.|..|.. | .|..|. DGFTPLHLACRCGHTEVVKMLL |
|||||||||
Ank | GL50803_8961.AA | Ank | 839-860 | 36 | 0.000913 | 17.84 | Pfam | 1-22 (33) | Show / Hide |
Range on Protein: 839-860 Range on HMM: 1-22/33 Sequence Identity: 36% (8 aa) GGKTALMLAAQARHPNCVRALI | |.|.||.. |...|. |. DGFTPLHLACRCGHTEVVKMLL |
|||||||||
Ank | GL50803_8961.AA | Ank | 911-933 | 26 | 32.774066 | 1.41 | Pfam | 1-23 (33) | Show / Hide |
Range on Protein: 911-933 Range on HMM: 1-23/33 Sequence Identity: 26% (6 aa) AGWPALFYAVVSGDSISASLLLE |. .| .|. .|. ...||. DGFTPLHLACRCGHTEVVKMLLQ |
|||||||||
Ank | GL50803_8961.AA | Ank | 942-960 | 36 | 0.046925 | 11.67 | Pfam | 1-19 (33) | Show / Hide |
Range on Protein: 942-960 Range on HMM: 1-19/33 Sequence Identity: 36% (7 aa) QGQTALDLAAERGDLELIE |.|.| ||...|..| .. DGFTPLHLACRCGHTEVVK |