Gene GL50803_221692 (G.lamblia)

GL50803_221692

Species: G.lamblia
Alias: GK007, GL50803_221692
External Links: GiardiaDB ,
Annotation:

Classification

Group: AGC
Family: PTF
Subfamily: FPK

Sequence

Name Sequence Type Origin Length Description Download
GL50803_221692.AA Protein None 589 None Fasta, JSON
GL50803_221692.kin_dom Protein Kinase Domain None 297 None Fasta, JSON

Protein domain

Protein domains of GL50803_221692.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase GL50803_221692.AA AGC 60-356 27 4.4e-123 319.69 In-house 1-395 (395) Show / Hide 
Range on Protein: 60-356
Range on HMM: 1-395/395
Sequence Identity: 27% (113 aa)

FQILCLLGIGDAGRVYLV-KRSSEKVLIPTGRNE-TVFALKVCSQHD---LTKRNKVNRFFTE------------LHILMTSR----------HPFIMT-
|..| ..| |  |.|||| |.....     ..    ..|.||..  .   ..|.|.| .  ||             .||.. .          ||||   
FEFLKVIGKGSFGKVYLVRKKDGCH-----KKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKI

LHASFADERN--FYLLMEFCN---------GG-EFAEVLKRQ-PNRCFPESTVQHYAAE-------ILTAFEYLHY-HGIIYRD-LKTENVLLHHDGHIR
|| || |...   |..||...         || |.   |. .  ...|.|.....||||       |. |.||||  .|||.|| || ||.|| .||||.
LHYSFQDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIK

LTDFDLAKRLTLG---------------------------ATVDHYKPVQLSVGKKTTTIFPTGFQ----------ETTASLVG--TPECLPPEVLQGEH
|||| |.|..  .                           .           . .. ...  ....          ..| ...|  ||| ..||.|   .
LTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTN-----------K-CNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL---Y

SQAADWWT--LGIFIYECLYGVTPFMSKGAS--------LDTISKKILRGVFTFPDG---P----------YKVSKKCKDLIKRLLDINPKTRLGSKM--
..|.|||.  ||...|| |.| .|| ..            . . .||. | ......   |           ..|. .|||||.||  .|. |||..   
GKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGND

----GASELKNHPFF
    ||.|.||||.|
FGDKGAEEIKNHPWF
Kinase GL50803_221692.AA RSK-Unclassified 60-356 41 1.4e-97 307.09 In-house 1-283 (283) Show / Hide 
Range on Protein: 60-356
Range on HMM: 1-283/283
Sequence Identity: 41% (125 aa)

FQILCLLGIGDAGRVYLVKRSSEKVLIPTGRNETVFALKVCSQHDLTKRNKVNRFFTELHILMTSRHPFIMTLHASFADERNFYLLMEFCNGGEFAEVLK
|    |.| || |.||||.   .|        . ..|.|| . | . ..||. .  ||  |. |. |||| ||  ||  .   || ||.| ||.| . | 
FIKHRLIGQGDFGKVYLVR---KK------DTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQ

RQPNRCFPESTVQHYAAEILTAFEYLHYHGIIYRDLKTENVLLHHDGHIRLTDFDLAKRLTLGATVDHYKPVQLSVGKKT---TTIFPTGFQETTASLVG
    .|| |  |. ||.|.  | ||||  ..|||||| .|..||..||..|||||| .  .     |  |||     . |   | |   ||   | | .|
TRKEKCFCEDDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAK-----DSKKPVMKGSAQSTYVDTKICDHGFR--TNSFCG

TPECLPPEVLQGE-HSQAADWWTLGIFIYECLYGVTPFMSKGASLDTISKKILRGVFTFPDGPYKVSKKCKDLIKRLLDINPKTRLGSKMG-ASELKNHP
| | | ||....  |  | ||||||| .|| | |..|.  .|   . . . |...   ||.  | .|..|.||||.||  ||  |||.||| | . | ||
TEEYLAPEMIRRCGHTKAVDWWTLGIVMYEMLFGCPPY--YGNNKNETFYNIEKNHVKFPHDSY-ISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHP

FF
||
FF
Kinase GL50803_221692.AA RSK 63-356 33 5.9e-90 305.15 In-house 1-278 (278) Show / Hide 
Range on Protein: 63-356
Range on HMM: 1-278/278
Sequence Identity: 33% (104 aa)

LCLLGIGDAGRVYLVKRSSEKVLIPTGRNETVFALKVCSQHDLTKRNK-VNRFFTELHILMTSR-HPFIMTLHASFADERNFYLLMEFCNGGEFAEVLKR
| .|| |. | |.|...   .       .....| || ... . .|.| . . .||  ||.... |||| ||| .| .|  .|| ||.|.|||. . |..
LKVLGQGGYGKVFLCRKCTHHD------TGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQK

QPN-RCFPESTVQHYAAEILTAFEYLHYHGIIYRDLKTENVLLHH---DGHIRLTDFDLAKRLTLGATVDHYKPVQLSVGKKTTTIFPTGFQETTASLVG
.    || |.... |.|||  | |.|| .|||.|||| ||.|...   .|||.||||...| .                        .  . . | . ..
EKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF------------------------RCDHNQWTMTFCY

TPECLPPEVLQ----GE-HSQAADWWTLGIFIYECLYGVTPFMSKGAS--LDTISKKILRGVFTFPDGP--YKVSKKCKDLIKRLLDINPKTRLGS-KMG
| | ..||.|     .. |..|.|||.||. .|| | | .|| . ...   . |.|.|..| |.. ..|   ..|. .||||...|  .|. |||. ...
TIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQG-PNDNNRKEIMKRIQKGKFSL-TMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQD

ASELKNHPFF
|.|.|.||.|
AEEIKQHPWF
Kinase GL50803_221692.AA S_TKc 60-356 27 2.8e-82 280.57 SMART 1-231 (231) Show / Hide 
Range on Protein: 60-356
Range on HMM: 1-231/231
Sequence Identity: 27% (84 aa)

FQILCLLGIGDAGRVYLVKRSSEKVLIPTGRNETVFALKVCSQHDLTKRNKVNRFFTELHILMTSRHPFIMTLHASFADERNFYLLMEFCNG--GEFAEV
..|| ..| |  |.||...  .            ..|.|. .          ...  |. ||.  .||.| .|. .| |  ..|. ||.|.|  |.  ..
YEILRKIGKGAFGKVYKCRHKK---------TGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDY

LKRQPN----RCFPESTVQHYAAEILTAFEYLHYHGIIYRDLKTENVLLHHDGHIRLTDFDLAKRLTLGATVDHYKPVQLSVGKKTTTIFPTGFQETTAS
.|...     . ||| ....|...|. | ||.| ||||.|||| ||.|| .  || ..|| ||..|                                 .
IKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------------------------------TT

LVGTPECLPPEVLQGEHSQ-AADWWTLGIFIYECLYGVTPFMSKGASLDTISKKILRGVFTFPDGPYKVSKKCKDLIKRLLDINPKTRLGSKMGAS---E
..|||. ..||||   ..  ..||| .|. .||.|.| .||      .... |||.             |. .||.|...|. .|. |..         .
FCGTPWYMAPEVL--GYGKCKCDWWSCGCILYEMLCGYPPFP----QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWD

LKNHPFF
 |.||.|
IKCHPWF
Kinase GL50803_221692.AA AktR 60-356 35 7.5e-80 271.59 In-house 1-268 (268) Show / Hide 
Range on Protein: 60-356
Range on HMM: 1-268/268
Sequence Identity: 35% (110 aa)

FQILCLLGIGDAGRVYLVKRSSEKVLIPTG-RNETVFALKVCSQHDLTKRNKVNRFFTELHILM-TSRHPFIMTLHASFADERNFYLLMEFCNGGEFAEV
|... .|| |  |.||||..         .  |  ..|.|. . ... .||.  .  ||  |.   ..||||  || .|..... ...||.| |||   .
FHVYKCLGKGAFGKVYLVQK---------KRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQH

LKRQPNRCFPESTVQHYAAEILTAFEYLHYH-GIIYRDLKTENVLLHHDGHIRLTDFDLAKRLTLGATVDHYKPVQLSVGKKTTTIFPTGFQ----ETTA
||.  .. | |.... |.|.|| |.||||.|  ||||||| || ||  |||...||| |.|                             |.    |.. 
LKK--KKKFSEEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK---------------------------LQFMMHYDEKAY

SLVGTPECLPPEVLQGE--HSQAADWWTLGIFIYECLYGVTPFMSKGASLDTISKKILRGVFTFPDGPYKVSKKCKDLIK-RLLDINPKTRLG-SKMGAS
|..|||| ..||... .  |  ..|||..|||||| ..| .|| .|    . ...|| .  . ||. | ..|..|||||. .||. ||. ||| ...|..
SFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQ-QNKFPY-PSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWE

ELKNHPFF
|.|.||.|
EIKSHPWF
Kinase GL50803_221692.AA Pkinase 60-356 24 1.3e-67 235.68 Pfam 1-293 (293) Show / Hide 
Range on Protein: 60-356
Range on HMM: 1-293/293
Sequence Identity: 24% (80 aa)

FQILCLLGIGDAGRVYLVKRSSEKVLIPTGRNETVFALKVCSQHDLTKRNKVNRFF-TELHILMTSRHPFIMTLHASFADERNFYLLMEFCNGG----EF
..|.  .| |  |.||. .. ..           ..|.|. . ..  .  .....  .|..|.   .||.| .|. .| |... |. ||.|.||    . 
YHIGRKIGSGSFGCVYKCHHKGTGK---------IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDL

AEVLKRQPNRCF--PESTVQHYAAEILTAFEYLHYHGIIYRDLKTENVLLHHDGHI----RLTDFDLAKRLTLGATVDHYKPVQLSVGKKTTTIFPTGFQ
....... ..||  .| ....|. .|| . ||.| .|||.|||| ||.|....|||    ...|| ||| .                         .  .
FDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD------------------------Y-NN

ETTASLVGTPECLPPEVLQ--GEHSQAADWWTLGIFIYECLYGVTPFMSK----GASLDTISKKILRGVFTFPDGPY------------------KVSKK
. . ...|||. ..|||..   ......|.| .|. .|| | | .|| ..    ... . . ..|... . |.                      ..|. 
S-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEE

CKDLIKRLLDINPKTRLGSKMGASELKNHPFF
|||.||..|. .|| |..    | ....||.|
CKDFIKWCLCKDPKKRPT----AEQILQHPWF
Kinase GL50803_221692.AA Ciliate-E2 60-356 21 3.7e-66 226.11 In-house 1-365 (365) Show / Hide 
Range on Protein: 60-356
Range on HMM: 1-365/365
Sequence Identity: 21% (85 aa)

FQILCLLGIGDAGRVYLVKRSSEKVLIPTGRNETV--------------FALKVCSQHDLTKRNKVNRFF----------TELHILMTSRHPFIMTLHAS
. .. ..| |  | ||..|. ... ..   ....               .|.|. .. ..   ..... .           |. || .  ||.|. .. .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FA--DERNFYLLMEFCNGGEFAEVLKRQPNRC---------FPESTVQHYAAEILT---------------AFEYLHYHG-IIYRDLKTENVLLHHDGHI
|   |. |.|| ||.|.||.  . .| ..  .         | |  .... ..||                |.||||  . ||.||.| ||.|.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

RLTDFDLAKRLTL-------GATVDHYKPVQLSVGKKTTTIFPTGF---QETTASLVGTPECLPPEVLQGE----------HSQAADWWTLGIFIYECLY
 ..|| |.|...        .     |.  .    . .. ..   .   |... ...|||. ..||.|.|.          .. ..|.| ||. .||.|.
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMD---QIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF

GVTPFMSKGASLDTISKKILRGVFTFPDGPY---------------KVSKKCKDLIKR----LLDINPKTRLGSKMGASELKNHPFF
| .||           ..|. . . ||   .               |.|..||||||.    .|. .|. |..   |.....|||.|
GKPPF----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT---GWEQILNHPWF
Kinase GL50803_221692.AA Ciliate-E2-Unclassified 60-356 21 1.4e-60 207.56 In-house 1-352 (352) Show / Hide 
Range on Protein: 60-356
Range on HMM: 1-352/352
Sequence Identity: 21% (84 aa)

FQILCLLGIGDAGRVYLVKRSSEKVLIPTGRNETVFALKVCSQHDLTKRNKVNRFFTELHILMTSR-------------------HPFIMTLHASFADER
. |.  .| |  | ||.......| ..    .    . |. ..... ..||  ..  |.....                      ||||. ..  | |. 
YKIIKQIGQGGFGKVYKCQHKKQK-QY----YAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQ

NFYLLMEFCNGGEFAEVLKRQPN---------------RCFPESTVQ-----HYAAEILTAFEYLHYHG-IIYRDLKTENVLLHHDG---HIRLTDFDLA
|.|. ||.|.||.  . .| ...               ..|.|  ..     .|.|.|| ..||||. . ||.||.| ||.|.. .|   .|...|| ..
NIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGIS

K--------RLTLGATVDHYKPVQLSVGKKTTTIFPTGFQ--------ETTASLVGTPECL----PPEVLQG-EHS----QAADWWTLGIFIYECLYGVT
|        . | .                         |        . . . .|||. .    .|||||| ...     ..|.|.||. .||.|.|  
KKYQQNNNCD-TNQ-------------------------QQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYY

PFMSKGASLDT--------------ISKKILRGVFTFPDGP-----YKVSKKCKDLIKRLLDINPKTRLGSKMGASELKNHPFF
|| ..    .               . ..|. . . ||  |     ...|...||.|..||  ..| ............|||.|
PFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase GL50803_221692.AA SGK 60-217 36 2.7e-49 150.14 In-house 1-173 (283) Show / Hide 
Range on Protein: 60-217
Range on HMM: 1-173/283
Sequence Identity: 36% (65 aa)

FQILCLLGIGDAGRVYLVKRSSE----------KVLIPTGRNETVFALKVCSQHDLT-------KRNKVNRFFTEL-HILMTSRHPFIMTLHASFADERN
|..| ..| |  |.||.||. ..          . |.    .. ..|.|| ..           |.....   .|   ||   .||||  || .|  .  
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLL-SQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWK

FYLLMEFCNGGEFAEVLKRQPNRCFPESTVQHYAAEILTAFEYLHYHGIIYRDLKTENVLLHHDGHIRLTDFDLAK
 |. |.. ||||    |.|   ..|||. .  |||||  | ||||   ||||||| ||.|| |.||..|||| |.|
LYFVMDYVNGGEMFYHLQRE--KHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCK
Kinase GL50803_221692.AA PKA 60-220 35 6.7e-43 148.85 In-house 1-152 (263) Show / Hide 
Range on Protein: 60-220
Range on HMM: 1-152/263
Sequence Identity: 35% (58 aa)

FQILCLLGIGDAGRVYLVKRSSEKVLIPTGRNETVFALKVCSQHDLTKRNKVNRFFTELHILMTSRHPFIMT-LHASFADERNFYLLMEFCNGGEFAEVL
|.|. .|| |  |||.|..        ..|     .|.|. ....  ... | .  .| .||.  .|||| . . ..| |.|. |..||...|||    |
FEIIQTLGTGSFGRVMLCR------HKHSG---NYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYL

KRQPNRCFPESTVQHYAA-EILTAFEYLHYHGIIYRDLKTENVLLHHDGHIRLTDFDLAKRLT
 .  ...|.... . ||| .|  |.|||| . ||||||| || |.  .||| .|||  ||...
RK--SGRFSNPHAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVD
Kinase GL50803_221692.AA Akt 60-217 42 2.6e-39 123.26 In-house 1-149 (264) Show / Hide 
Range on Protein: 60-217
Range on HMM: 1-149/264
Sequence Identity: 42% (68 aa)

FQILCLLGIGDAGRVYLVKRSSEKVLIPTGRNETVF-ALKVCSQHDLTKRNKVNRFFTELHILMTSRHPFIMTLHASFADERNFYLLMEFCNGGEFAEVL
|..| .|| |  |.|.|||   .|       .. .. |.|| .   . ..|.|   .||  || . .||||  || || .. . |. |..|||||    |
FDFLKVLGKGSFGKVFLVK---KK------DTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHL

KRQPNRCFPESTVQHYAAEILTAFEYLHYHGIIYRD-LKTENVLLHHDGHIRLTDFDLAK
.|.  | |.|..   |.|||  | |.|| ..||||| || ||.|. .||||.|||| |.|
QRK--RRFSEDRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCK
Kinase GL50803_221692.AA RSK 60-219 34 3.4e-38 133.21 In-house 1-155 (271) Show / Hide 
Range on Protein: 60-219
Range on HMM: 1-155/271
Sequence Identity: 34% (56 aa)

FQILCLLGIGDAGRVYLVKRSSEKVLIPTGRNETVFALKVCSQHDLTKRNKVNRFFTELHILMTSRHPFIMTLHASFADERNFYLLMEFCNGGEFAEVLK
. ..  .| |  . ||..|.   |       ... .| |.     .  . .  .  .|  ||  . |||| .|| .| ||.. |. |.|. ||.    | 
YELHECIGQGSFSKVYVCKKCQHK------DTNQHYAMKIIKKATRDVKDR-VCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLL

RQPNRCFPESTVQHYAAEILTAFEYLHYHGIIYRDLKTENVLLHHD----GHIRLTDFDLAKRL
.|  ..|.|. |  |.|||. | |||| .||..|||| ||.|.  .    |||...|| .|| |
KQ--KMFSEREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQL
Kinase GL50803_221692.AA Akt 248-356 41 3.4e-35 109.9 In-house 156-264 (264) Show / Hide 
Range on Protein: 248-356
Range on HMM: 156-264/264
Sequence Identity: 41% (47 aa)

QETTASLVGTPECLPPEVLQGE-HSQAADWWT-LGIFIYECLYGVTPFMSKGASLDTISKKILRGVFTFPDGPYKVSKKCKDLIKRLLDINPKTRLG-SK
...| .. |||| |.||.|.|  |..|.|||. ||...|| ..|  || ..    ..  |||. .   |||   ..|..|||||..||  .|| |||  .
HDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPFYNQDH--HQMFKKIKNQPVKFPDK-DWISPECKDLISGLLNKDPKKRLGGGP

MGASELKNHPFF
 .| |.|.||.|
NDAQEIKRHPWF
Kinase GL50803_221692.AA SGK 249-356 41 1.1e-32 97.86 In-house 180-283 (283) Show / Hide 
Range on Protein: 249-356
Range on HMM: 180-283/283
Sequence Identity: 41% (45 aa)

ETTASLVGTPECLPPEVLQGE-HSQAADWWTLGIFIYECLYGVTPFMSKGASLDTISKKILRGVFTFPDGPYKVSKKCKDLIKRLLDINPKTRLGSKMGA
.|| .  |||| | ||||... |. . ||| ||.. || .||  || |.  .  .   .|...   .| .   .| ...|||. ||  .|| |||.| ..
DTTFTFCGTPEYLAPEVLRKQPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQ--QMYDNIINQPLQIPPQ---MSNDAWDLIQGLLQKDPKKRLGTKRDF

SELKNHPFF
 | ||||||
MEIKNHPFF
Kinase GL50803_221692.AA PKA 256-356 39 1e-25 91.74 In-house 160-263 (263) Show / Hide 
Range on Protein: 256-356
Range on HMM: 160-263/263
Sequence Identity: 39% (42 aa)

GTPECLPPEVLQGE--HSQAADWWTLGIFIYECLYGVTPFMSKGASLDTISKKILRGVFTFPDGPYKVSKKC---KDLIKRLLDINPKTRLGSKM-GASE
|||| |.||..|..  |  . |||.||| ||| | |..||  .. .   | .||. |   ||     ....    |||||.||  ... |.|..  |.  
GTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFYDHNRDPMQIYEKICNGKIKFPR---HFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVND

LKNHPFF
 |||..|
IKNHKWF
Kinase GL50803_221692.AA RSK 263-356 40 7e-22 75.01 In-house 174-271 (271) Show / Hide 
Range on Protein: 263-356
Range on HMM: 174-271/271
Sequence Identity: 40% (40 aa)

PEVL--QGEHSQAADWWTLGIFIYECLYGVTPFMSKGA-SLDTISKKILRGVFTFPDG-PYKVSKKCKDLIKRLLDINPKTRLGS-KMGASELKNHPFF
||||  || |.||.||| .|.  || | | ||| .|   ....| ..|  | |..  | . ..|. .|||. ..|...|  |||.   |. . |.||.|
PEVLKRQG-HDQACDWWSFGVLMYEMLTGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF
Kinase GL50803_221692.AA TyrKc 60-350 17 5.2e-11 -44.7 SMART 1-280 (280) Show / Hide 
Range on Protein: 60-350
Range on HMM: 1-280/280
Sequence Identity: 17% (56 aa)

FQILCLLGIGDAGRVYLVKRSSEKVLIPTGRNETVFALKVCSQHDLTKRNKVNRFFTELHILMTS--RHPFIMTLHASFADE-------RNFYLLMEFCN
 . .  || |  |.||. . .            .  | |..  .       .  |  |. |..    .|| |  |..   ..          ...||.. 
ITLGKKLGEGAFGEVYKGTWK------------IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMP

GGEFAEVLKRQPNRCFPESTVQHYAAEILTAFEYLHYHGIIYRDLKTENVLLHHDGHIRLTDFDLAKRLTLG----ATVDHYKPVQLSVGKKTTTIFPTG
.|   . |..  .. .. ..  ...  |    |||| ...| ||| . |.|........ .|| |.. .. .    .  | |.. . . ||    |    
HGDLKDYLRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIR---

FQETTASLVGTPECLPPEVL-QGEHSQAADWWTLGIFIYECL-YGVTPFMSKG-----ASLDTISKKILRG-VFTFPDGPY-----KVSKKCKDLIKRLL
              ..||..  |. . . | |  |. ..| . || .|    |      | . . ... .|     |. .|       ...  ...|.  
-------------WMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPY--PGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCW

DINPKTRLGSKMGASEL
. .|. |   .   ...
HEDPEDRPTFSEIHECF
Kinase GL50803_221692.AA Pkinase_Tyr 96-213 20 1.1e-07 26.59 Pfam 32-155 (270) Show / Hide 
Range on Protein: 96-213
Range on HMM: 32-155/270
Sequence Identity: 20% (26 aa)

ALKVCSQHDLTKRN-KVNRFFTELHILMTS-RHPFIMTLHASFA-DERN--FYLLMEFCNGGEFAEVLKRQ--PNRCFPESTVQHYAAEILTAFEYLHYH
| |..  .. .... .   |. |. |...  .|| |  |..    ...    |. ||.. .|   . |...  ... .. ..  .....|  . |||. .
AVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESK

GIIYRDLKTENVLLHHDGHIRLTDF
..| ||| . |.|........ .||
NCIHRDLAARNCLVTENNVVKICDF