Gene GL50803_16792 (G.lamblia)

GL50803_16792

Species: G.lamblia
Alias: GL50803_16792, GK257
External Links: GiardiaDB ,
Annotation:

Classification

Group: Other
Family: Nek
Subfamily: Nek-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
GL50803_16792.AA Protein None 455 None Fasta, JSON
GL50803_16792.kin_dom Protein Kinase Domain None 260 None Fasta, JSON

Protein domain

Protein domains of GL50803_16792.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase GL50803_16792.AA NEK 5-264 36 1.5e-107 363.62 In-house 1-286 (286) Show / Hide 
Range on Protein: 5-264
Range on HMM: 1-286/286
Sequence Identity: 36% (105 aa)

FVKQTLLGEGSYGRAYLATDNVSNES-----VVIKEFVGKKMSTNAKRLAM-EECALLSKMNNPNIVAYFGHFMQNG--NLSIVMEYAN-KGDLSGL---
. ..  .|.||.|..|.. .   .       .|.|.   ..||   |. |. .|. .|.....||||.|. .|. ..   | |||||.. .|||. .   
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS

INKAN--GKRISEEIIKDIFYQLIKAVAYIHKR-----NILHRDIKAGNIFLTSAPDSNFY-RVMLADFGVSKVLSNDDALTET-LAGTPYYLSPELCNS
|.|    || ..||.| |.|.|...|. |.|.|     .|||||||  |||||.  . | |  | . |||.||||...  .  | . |||||.|||.|..
IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTK--NNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQN

EPYGKKSDMWALGIVLYELMMLTT--PFRGK--NLQAVSARITRG-KFPEITGP--YSEAIKNVCYSLLRNDPNERPSAVQLLDHKMF
.||. |||.|.|| ||||...|    ||...  |. .   .|..| ..| |     ||.  .|.  ..|. || .|||. |.| .   
KPYNNKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase GL50803_16792.AA NEK1 5-264 39 4.3e-100 338.82 In-house 1-276 (276) Show / Hide 
Range on Protein: 5-264
Range on HMM: 1-276/276
Sequence Identity: 39% (108 aa)

FVKQTLLGEGSYGRAYLATDNVSNESVVIKEFVGKKMSTNAKRLAMEECALLSKMNNPNIVAYFGHFMQNGN--LSIVMEYANKGDLSGLINKA--NGKR
....  .||||.|.|.|...  ..   ||||    ||.   .  .|.| |.|.||  ||||.|.  |  ||.  | |||||.. |||   ||..   || 
YHYIKQIGEGSFGKAWLVKHKEDGQHYVIKEINVMKMQEKEREESMNEVAILAKMKHPNIVKYKESFEENGCGILYIVMEYCDGGDLMQKINRQKRKGKL

ISEEIIKDIFYQLIKAVAYIHKRNILHRDIKAGNIFLT-SAPDS-----------NFYRVMLADFGVSKVLSNDDALTETLAGTPYYLSPELCNSEPYGK
.||  | . | |. .|. .||.|.|||||||. ||||| |  ..               | |.|||....|.. ...  | .|||||||||.|.  ||  
FSEDQIMHWFCQICLALNHIHDRKILHRDIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGIARMLNHTMEYACTCIGTPYYLSPEICQNKPYNN

KSDMWALGIVLYELMMLTTPFRGKNLQAVSARITRGKFPEITGPYSEAIKNVCYSLLRNDPNERPSAVQLLDHKMF
|||.|.|| |||||. |. || ..|...   .|..| .| |   ||. ...   .... .|  |||. |.|     
KSDIWSLGCVLYELCTLKHPFEANNWKNLVLKICQGTYPPIPPHYSYELQSLVSQMFKRNPRHRPSVNQILERPFI
Kinase GL50803_16792.AA NEK8 31-264 36 9.3e-89 253.51 In-house 29-278 (278) Show / Hide 
Range on Protein: 31-264
Range on HMM: 29-278/278
Sequence Identity: 36% (92 aa)

VVIKEFVGKKMSTNAKRLAMEECALLSKMNNPNIVAYFGHFMQNGNLSIVMEYANKGDLSGLINKANGKRISEE-----------------IIKDIFYQL
|..|.     || .  ..|. |. .||. . |||..|..||| .. | |.||||. | |  .|..  .|  .||                  | . | | 
VIWKQINMHRMSEKERQMAQNEIQVLSMLQHPNIISYYDHFMEDNTLMIEMEYADGGTLYQMIQHQQNKLFEEERQLKQVNHCFNIYFNEQMILWYFFQM

IKAVAYIHKRNILHRDIKAGNIFLTSAPDSNFYRVMLADFGVSKVLSND-DALT-ETLAGTPYYLSPELCNSEPYGKKSDMWALGIVLYELMMLTTPFRG
  ||...|. ||||||.|  |||.| .   ..  | . ||| ||... .  . |  |. |||||.|||.| . ||  |||||||| ||||.  |   | .
CSAVHHMHQHNILHRDLKTQNIFMTRH--RMV--VKIGDFGISKIMNTKYHMQTTKTVVGTPYYMSPEMCEGKPYNQKSDMWALGCVLYEMCCLKRAFEA

KNLQAVSARITRG-KFPEITGPYSEAIKNVCYSLLRNDPNERPSAVQLLDHKMF
 || |.   |... ..  | ..||   . .  ..|  ||  |||| |...    
SNLPALVWKIMQCRAYEPISDHYSNEMRMLVHNCLQQDPEQRPSASQIMAMPLC
Kinase GL50803_16792.AA S_TKc 5-264 27 4.6e-86 293.14 SMART 1-231 (231) Show / Hide 
Range on Protein: 5-264
Range on HMM: 1-231/231
Sequence Identity: 27% (75 aa)

FVKQTLLGEGSYGRAYLATDNVSNESVVIKEFVGKKMSTNAKRLAMEECALLSKMNNPNIVAYFGHFMQNGNLSIVMEYANK--GDLSGLINKANGKR--
. .  ..|.|..|. |..... ... | ||.           . .. | ..|.| . |||| ....|   ..| .||||..   |||  .| | ....  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--ISEEIIKDIFYQLIKAVAYIHKRNILHRDIKAGNIFLTSAPDSNFYRVMLADFGVSKVLSNDDALTETLAGTPYYLSPELCNSEPYGK-KSDMWALGI
  ..|  .. ..||...|..|.|...|.|||.|  ||.|..       .....|||....|        |. |||.|..||..   .||| |.|.|..|.
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC

VLYELMMLTTPFRGKNLQAVSARITRGKFPEITGPYSEAIKNVCYSLLRNDPNERPSAVQLLD-------HKMF
.|||..   .||.  ..|..  .|            |.  |.    .|. ||..||.| ..|        |  |
ILYEMLCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase GL50803_16792.AA Pkinase 5-264 25 3.5e-77 267.54 Pfam 1-293 (293) Show / Hide 
Range on Protein: 5-264
Range on HMM: 1-293/293
Sequence Identity: 25% (76 aa)

FVKQTLLGEGSYGRAYLATDNVSNESVVIKEFVGKKMSTNAKRLAME--ECALLSKMNNPNIVAYFGHFMQNGNLSIVMEYANKG----DLSGLINKANG
...   .|.||.|. |....  ... |..|..  .. . . .. .    |.... ..| |||| ... |. .... .||||...|    ||. .|   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KRI--SEEIIKDIFYQLIKAVAYIHKRNILHRDIKAGNIFLT--SAPDSNFYRVMLADFGVSKVL-SNDDALTETLAGTPYYLSPELCN-SEPYGKKSDM
...  ||. .|...||......|.|...|.|||.|  ||..     .|.   .| ..|||..|..    .  . |..|||.|..||... ...||.|.||
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA---CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WALGIVLYELMMLTTPFRGK------NLQAVSARITRGKFPEITGPYS--------------------EAIKNVCYSLLRNDPNERPSAVQLLDHKMF
|..|..|||..   .||.|.      . ... .|| ......     .                    |. | .....|. ||..||.| |.| |. |
WSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase GL50803_16792.AA CAMK 10-264 18 5.8e-66 211.27 In-house 1-425 (425) Show / Hide 
Range on Protein: 10-264
Range on HMM: 1-425/425
Sequence Identity: 18% (79 aa)

LLGEGSYGRAYLATDNVSN------------ESVVIKEFVGKKMS--------------------------TNAKRLAMEECALLSK-------MNNPNI
 ||.||.|  .|...  ..            . | ||    ||..                           . ..  . | ....|       .. |||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VAYFGHFMQNGN-------------------LSIVM---EYANKG----DLSGLINKANG-------------KRISEEIIKDIFYQLIKAVAYIHKRNI
.  . ..  . .                   . .||   ||.  |    ||   | .  .             .|..|.  . .| |.. ||.|.|..||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

LHRDIKAGNIFLTSAPD------------SNFYRVMLADFGVSKVLSN-----------------------DDALTETLAGTPYYLS-PELCNS------
 |||.|  || |..  |            .| . . ..||| ....                         .. . .|  |||.| . ||. |.      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------EPYGKKSDMWALGIVLYELMMLTTPFRGK-------------NLQAVSARITRGKFPEITGP---------------YSEA--------IKN
        ..||.|.|||..|..|| .   . ||.|.             |..    .|..||.  .  .                |.          |.
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

VCYSLLRNDPNERPSAVQLLDHKMF
   ..|. ||..|... | |.|. .
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase GL50803_16792.AA Ciliate-E2 5-264 21 2.8e-62 212.61 In-house 1-365 (365) Show / Hide 
Range on Protein: 5-264
Range on HMM: 1-365/365
Sequence Identity: 21% (83 aa)

FVKQTLLGEGSYGRAYLATD-NVSNES-----------------VVIKEFVGKKMSTNAKRLAMEECALLSKMN----------------NPNIVAYFGH
. .. ..|.|..|  |.... .| ...                 | ||..  | |. | ..  . |  .. ..|                .|||. .. .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FM--QNGNLSIVMEYANKGDLSGLIN-----------KANGKRISEEIIKDIFYQLIK---------------AVAYIHKRN-ILHRDIKAGNIFLTSAP
|   .. |. .||||.. |||  .|.           |   |...|. ||.|..|...               |. |.|..| |.|||||  ||..    
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEK-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

DSNFYRVMLADFGVSKVLSND-------------------------------DALTETLAGTPYYLSPELCNSEP---------YGKKSDMWALGIVLYE
      . ..||| || ...|                               . .. |..|||.|..||  |...         |..|.|.|.||..|||
------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYE

LMMLTTPFRGKNLQAVSARITRGKFPE-------------ITGPYSEAIKNVCYS----LLRNDPNERPS-AVQLLDHKMF
...  .||    .|       .  .||             ..   |.  |. .      .|  ||..|.. . |.|.|. |
MLFGKPPF----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase GL50803_16792.AA STE 5-264 21 5.2e-62 212.32 In-house 1-359 (359) Show / Hide 
Range on Protein: 5-264
Range on HMM: 1-359/359
Sequence Identity: 21% (80 aa)

FVKQTLLGEGSYGRAYLATDN------VSNES---------VVIKEFVGKKMST---------------NAKRLAMEECALLSKMN--NPNIVAYFGHFM
. ..  .|.|..|  |.| ..       ..|          . ||.   .. ..               . .   ..|  ...|.|   |||| |.|...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

QNG-------NLSIVMEYANKGDLSGLIN---KANG---------KRISEEIIKDIFYQLIKA-VAYIHKRNILHRDIKAGNIFLTSAPDSNFYRVMLAD
..|       .| |.||| . | |. .|.   . ..         .|..|..|. | .|..|.  .|.|. .| |||||..||.|          | |.|
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL----------VKLCD

FGVSKVLSN---------------DDA-LTETLAGTPYYLSPELCNS------EPYGKKSDMWALGIVLYELMMLTTPFRG-KNLQAVSARITR------
|||.. |..               . .  . |..||| . .||  .        .|. |.|.| ||... |.     |.   ....|  . ..       
FGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQ

--------GKFPEITGP-------------------YSEAIKNVCYSLLRNDPNERPSAVQLLD--HKMF
        |. | .  .                   .|.  |.     |. |||.||.| |||   |. .
FEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase GL50803_16792.AA ULK 5-264 25 1.6e-58 200.74 In-house 1-329 (329) Show / Hide 
Range on Protein: 5-264
Range on HMM: 1-329/329
Sequence Identity: 25% (84 aa)

FVKQTLLGEGSYGRAYLATDNVS----NESVVIKEFVGKKMSTNAKR--------LAMEECALLSKMN--------NPNIVAYFGHFMQN--GNLSIVME
...   ||.||.|. | .... .    || |..|    .||. . .         | . |. .. |..        .|||| ..  |.     |. |.||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YANKGDLSGLINKA--------NGKRISEEIIKDIFYQLIKAVAYIHKRNILHRDIKAGNIFLTS---------APDSNFYRVMLADFGVSKVLSND---
| | |||. .|.|         ..||.||.... .|.|.. .  ..||.|| |||||  || ..          .  .  ... .|||| .|...||   
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKV-HP-NGVLKIADFGFAKHVDNDNME

DALTETLA------GTPYYLSPELCN----SEPYG-KKSDMWALGIVLYELMMLTTPFRGKNLQAVS-----ARITRG------------KFPE--ITGP
.... |        |||.| .|.. .     .||. .|.|.| ||...||.    .||..   .          |  .            .||      .
QQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQ

YSEAIKNVCYSLLRNDPNERPSAVQLLDHKMF
 |. .|.  . .|  |...| |  .|..|. |
ISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase GL50803_16792.AA NEK4 4-264 33 2.1e-57 197.04 In-house 2-257 (257) Show / Hide 
Range on Protein: 4-264
Range on HMM: 2-257/257
Sequence Identity: 33% (87 aa)

RFVKQTLLGEGSYGRAYLATDNVSNESVVIKEFVGKKMSTNAKRLAMEECALLSKMNNPNIVAYFGHFMQNGN--LSIVMEYANKGDLSGLINKANGKRI
 ..|.   | ||||  .|          |.|    |. |   .. |  |  |||..  |||| |.  .    .  | ||| . . |||     .  .. .
CHMKV--VGKGSYGEVWLVRHRRDKKQYVMKKMFLKNASRRERKAAEHEAQLLSQLKHPNIVEYKESWEIENGQFLYIVMGFCEGGDLYRKLKQQKNQFL

SEEIIKDIFYQLIKAVAYIHKRNILHRDIKAGNIFLTSAPDSNFYRVMLADFGVSKVLSNDDALTETLAGTPYYLSPELCNSEPYGKKSDMWALGIVLYE
.|. . . | |   |  |.|...||||| |  |||||     |  ..   |||.|.|| |   . .|. |||||.|||.  . ||  |||.|.||  .||
EEYQVVEWFVQIAMALQYMHEKHILHRDLKTQNIFLTKK---NIIKI--GDFGISRVLNNHCDMAKTMIGTPYYMSPECFGNRPYDYKSDIWSLGCCVYE

LMMLTTPFRGKNLQAVSARITRGKFPEITGPYSEAIKNVCYSLLRNDPNERPSAVQLLDHKMF
.. |   |  |..     .|  |. | .   ||. ..|  | .|   |..|||  ...     
MITLKHAFDAKDMNSLIYQIIQGQPPPMPPNYSQDLQNLVYQMLEKQPTKRPSIFDIFQMPYI
Kinase GL50803_16792.AA ULK 5-264 24 4.2e-57 196.02 In-house 1-324 (324) Show / Hide 
Range on Protein: 5-264
Range on HMM: 1-324/324
Sequence Identity: 24% (81 aa)

FVKQTLLGEGSYG-RAYLATDNVS---NESVVIKEFVGKKMSTNAKR--------LAMEECALLSKMN---NPN--IVAYFGHFMQN--GNLSIVMEYAN
...   ||.||.|   | .... .   |. | .|    |||. . ..        | . |  .. |..   .||  || ..  |.     |. |.||| |
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

KGDLSGLINKA-------NGKRISEEIIKDIFYQLIKAVAYIHKRNILHRDIKAGNIFLTS---------APDSNFYRVMLADFGVSKVLSNDD---ALT
 |||. .|.|        ..||.||.... .|.|.. .  ..||.|| |||||  || ..          .  .  ... .|||| .|.. |..    ..
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKV-HP-NGVLKIADFGFAKHVDNNNMEQQMC

ETLA------GTPYYLSPELCN----SEPYG-KKSDMWALGIVLYELMMLTTPFRGKNLQAVSAR--------------ITRGKFPEITGP----YSEAI
 |.       |||.| .|.. .     .||. .|.|.| ||...||.    .||..   .    .              |   ...   .|     |. .
QTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPEC

KNVCYSLLRNDPNERPSAVQLLDHKMF
|.  . .|  |...| |  ....|. |
KDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase GL50803_16792.AA Ciliate-E2-Unclassified 5-264 21 3e-53 183.05 In-house 1-352 (352) Show / Hide 
Range on Protein: 5-264
Range on HMM: 1-352/352
Sequence Identity: 21% (75 aa)

FVKQTLLGEGSYGRAYLATDNVSNESV-------VIKEFVGKKMSTNAKRLAMEECALLSK------------------MNNPNIVAYFGHFMQNGNLSI
. ..  .|.|..|  |.. ..  .  .       .|...  |.. ..  .. .|. .. .|                  ...|.|| .| .| .  |. |
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

VMEYANKGDLSGLINKANG---------------KRISEEIIK-----DIFYQLIKAVAYIHKRN-ILHRDIKAGNIFLTSAPDSNFYRVMLADFGVSKV
||||.. |||.  |.| ..               |...|. .|     ..|.|....  |.|. | |.|||||  ||....      |.. ..||| || 
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK--NYYIKIIDFGISKK

LSND---------------DALTETLAGTPYYL----SPELCNSEPYG----KKSDMWALGIVLYELMMLTTPFRGKNLQA----------------VSA
. ..               . .. | .|||.|.    .||.  .. |.    .|.|.|.||..|||... . || ..|                   .  
YQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQ

RITRGKFP-----------EITGPYSEAIKNVCYSLLRNDPNERPSAVQLLDHKMF
 |  ...             .   . . |.. . ..| ..||.|... |.| |  |
NIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase GL50803_16792.AA TyrKc 5-264 22 5.8e-17 51.58 SMART 1-280 (280) Show / Hide 
Range on Protein: 5-264
Range on HMM: 1-280/280
Sequence Identity: 22% (66 aa)

FVKQTLLGEGSYGRAYLATDNVSNESVVIKEFVGKKMSTNAKRLAMEECALLSKM--NNPNIVAYFGHFMQN-------GNLSIVMEYANKGDLSGLINK
 ..   |||| .|. |..| .   . | .|     .     ..  |.|  ...|   ..||||. .|  .|        . | |||||. .|||   . |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

ANGKRISEEIIKDIFYQLIKAVAYIHKRNILHRDIKAGNIFLTSAPDSNFYRVMLADFGVSKVLSND-------DALTETL--AGTP----YYLSPELCN
  .| .. .   .. .|  .  .|.|..|. |||. | |. ...       .|  .||| |. . .|       |  . .    |        ..||  |
HRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECIN

SEPYGKKSDMWALGIVLYELMML-TTPFRG-----KNLQAVSARITRGKFPEITGP--------YSEAIKNVCYSLLRNDPNERPSAVQLLDHKMF
   .  ||| |. |....|.. .  .|  |     .. | | ... .|. ...            .... ..  .  . ||..||.  ..  |. |
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase GL50803_16792.AA Pkinase_Tyr 5-163 26 5.1e-13 44.71 Pfam 1-165 (270) Show / Hide 
Range on Protein: 5-163
Range on HMM: 1-165/270
Sequence Identity: 26% (45 aa)

FVKQTLLGEGSYGRAYLATDN----VSNESVVIKEFVGKKMSTNA---KRLAMEECALLSKM-NNPNIVAYFGHFM-QNGN--LSIVMEYANKGDLSGLI
 ..   ||||..|. |..| .      .  | .|    |  ..     ..  |.| ...... ..|||| . |  . | .   . |||||. .|||    
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML--KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

NKA--NGKRISEEIIKDIFYQLIKAVAYIHKRNILHRDIKAGNIFLTSAPDSNFYRVMLADFGVSKVLSNDD
 |   ...... . . .. .|  |. .| . .|. |||. | |. .|.    |.  |  .||| .. . |||
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE----NN-VVKICDFGLARDIYNDD
Kinase GL50803_16792.AA Pkinase_Tyr 189-224 28 0.014807 9.28 Pfam 194-232 (270) Show / Hide 
Range on Protein: 189-224
Range on HMM: 194-232/270
Sequence Identity: 28% (11 aa)

KSDMWALGIVLYELMMLT-TP-FRGKNLQAVSARI-TRG
||| |. |....|.. .  .| . |   . | ..|  .|
KSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDG