Gene GL50803_15397 (G.lamblia)
GL50803_15397
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
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GL50803_15397.AA | Protein | None | 340 | None | Fasta, JSON |
GL50803_15397.kin_dom | Protein Kinase Domain | None | 325 | None | Fasta, JSON |
Protein domains of GL50803_15397.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | GL50803_15397.AA | CMGC | 10-334 | 22 | 1.5e-92 | 304.4 | In-house | 1-513 (513) | Show / Hide |
Range on Protein: 10-334 Range on HMM: 1-513/513 Sequence Identity: 22% (122 aa) YEFISQIGEGTYGTVSKCSL----------------HGQLLAVKRIK---MDSSSK------GVPATTLREVAILKALNAK-----QRELVEQGKLESLS || |..|||||||.| || ... |.|.|| .. | |.| ..|||. ||| || . || . . .. YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQR---RD-DPDNKH QANVVNLLDVVYDLS-----------------NIFLVFEYCHVDLDQYLKHNV----------LSPYQ------------IKKFM------YQLLQGLS- |.|.|.|..|. ...|||||. || ||.|.| ||. . ||.|| ||.|.|| HNNIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKL -LVHKNE--ILHRDIKPNNILLA-----------------FRGDAGEQLAANASVTTPNPDADNCVLKITDFGLARSYGIN------------------- |.. |.|||.|| |||. . ..| .||| ||||||.|... KYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPC-------------------QKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDD --VTSISANVVSLWYRAPELVLASKTYS---------TAVDMWSMGCIMYFLANK--------RALFQ-----------VRKDADLLQLAFSYFYVD--- . .. .||..||||||. | .| |. |..|||| |||.. . .. . ||. ... | |.. | . KPNRPYTHYVVTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWM -------------SSSISDLISLPNWNMYVG---------ENQVIDLAALNAPGRKPREVDINID----------------------------------- . . . |.||..|.. . ... ..|.|. ... IQKGKRHFNFCKHEEEWPNMIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQ -------DVGKDLFYKLLMLNPSKRISCDEALQHPWF . . || |.| ..|.|||....|||||.| FKRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF |
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Kinase | GL50803_15397.AA | S_TKc | 10-334 | 24 | 1.5e-75 | 258.25 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 10-334 Range on HMM: 1-231/231 Sequence Identity: 24% (84 aa) YEFISQIGEGTYGTVSKCSLHG--QLLAVKRIKMDSSSKGVPATTLREVAILKALNAKQRELVEQGKLESLSQANVVNLLDVVYDLSNIFLVFEYCHV-- ||.. .||.|..|.| || .. .. |.|.|| ...||..||| |.|.|.|| .| .....|.||| YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-----------------HHPNIVKLYDVFQD-DHLYMVMEYCDGDL -DLDQYLKHNV-------LSPYQIKKFMYQLLQGLSLVHKNEILHRDIKPNNILLAFRGDAGEQLAANASVTTPNPDADNCVLKITDFGLARSYGINVTS || .|.|.. ... .....|||....| |.. |.|||.|| |||| ..||.|||||| . GDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------------------------HIKICDFGLARQL------ ISANVVSLWYRAPELVLASKTYST-AVDMWSMGCIMYFLANKRALFQVRKDADLLQLAFSYFYVDSSSISDLISLPNWNMYVGENQVIDLAALNAPGRKP . ....||.|||.. |.. ..|.|| |||.| .. . .|. .. .... -TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG----------------------------------------- REVDINIDDVGKDLFYKLLMLNPSKRISCDEALQ-------HPWF .. .||. |.| .|.||... |||| |||| -------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | GL50803_15397.AA | Pkinase | 10-334 | 27 | 8.5e-69 | 239.67 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 10-334 Range on HMM: 1-293/293 Sequence Identity: 27% (94 aa) YEFISQIGEGTYGTVSKCSLHGQ--LLAVKRIKMDSSSKGVPATTLR--EVAILKALNAKQRELVEQGKLESLSQANVVNLLDVVYDLSNIFLVFEYC-H |.....||.|..|.| || .| . |||.|| .. ..... | .| |..|.| || |.| |.|...| ..| .|.||| . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN----------------HPNIVRLYDWFEDKDHIYMVMEYCEG V----DLDQYLK---HNVL--SPYQIKKFMYQLLQGLSLVHKNEILHRDIKPNNILLAFRGDAGEQLAANASVTTPNPDADNCVLKITDFGLARSY-GIN || |.. |... |. ..|..|||.|.|| |.. |.|||.|| |||. .|. .. .||.|||||. . | GLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA------------------CVKICDFGLAKQFDY-N VTSISANVVSLWYRAPELVLASKTYSTAVDMWSMGCIMYFLANKRALFQVR----KDADLLQLAFSYFYVDSSSISDLISLPNWNMYVGENQVIDLAALN . . ....||.|||... .. |...|||||.|||.| ....| .|. . . .| .|. . . . .. .. . . . . . . NS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H------ APGRKPREVDINIDDVGKDLFYKLLMLNPSKRISCDEALQHPWF . .... .|... .||. ...| ..|.||......|||||| ---F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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Kinase | GL50803_15397.AA | CDC2 | 82-243 | 38 | 6.1e-62 | 188.93 | In-house | 62-210 (301) | Show / Hide |
Range on Protein: 82-243 Range on HMM: 62-210/301 Sequence Identity: 38% (66 aa) NVVNLLDVVYDLSNIFLVFEYCHVDLDQYLK-----HNVLSPYQIKKFMYQLLQGLSLVHKNEILHRDIKPNNILLAFRGDAGEQLAANASVTTPNPDAD |.| | ||.. .....||||.. || .|.. ...| .|..|||.|||.. | . |.|||.|| |||. |. NIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGN------------------- NCVLKITDFGLARSYGINVTSIS--ANVVSLWYRAPELVLASKTYSTAVDMWSMGCIMYFL---ANKRALFQ .|| |||||| ||.. . .|| |||||||. | .|.|||.||||| |||.. . ..|..||. ---IKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEMFMDVTKKPLFH |
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Kinase | GL50803_15397.AA | Ciliate-E2 | 10-334 | 20 | 3.8e-56 | 191.24 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 10-334 Range on HMM: 1-365/365 Sequence Identity: 20% (88 aa) YEFISQIGEGTYGTVSKC--SLHGQLL------------------AVKRIKMDSSSKGVPATTLREVAILKALNAKQRELVEQGKLESLSQANVVNLLDV |.|| .||.|..|.| || . ... ..| . | . .| ...| |.. .| ... . |. ||.|. |.... .. YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC VY--DLSNIFLVFEYCHV-DLDQYLKHN------------VLSPYQIKKFMYQLLQ---------------GLSLVHKNE-ILHRDIKPNNILLAFRGDA . | .||.||.||| || .|.|.| .. ..||..|.|.|| .| |.. |.||||||.|||. FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------ GEQLAANASVTTPNPDADNCVLKITDFGLARSYGIN----------VTSISAN----------------------VVSLWYRAPELVL--------ASKT .||.||||.. | .. . . . .. | ||| . ..| ---------------------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKG YSTAVDMWSMGCIMYFLANKRALFQVRKDADLLQLAFSYFYVDSSSISDLISLPNWNMYVGENQVI--DLAALNAPGRKPREVDIN---------IDDVG |....|.||.|.|.|.. .. | ..| . .. .. .|. .. ... . YDYKCDIWSLGVILYEMLFGKPPF-------------------------------------QQQIKQCKIDFPCPEWQKD-TQ-CIQCKWKSWKKWSQEC KDLFYK----LLMLNPSKRIS-CDEALQHPWF |||. | .| .|.|||. ...|.|||| KDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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Kinase | GL50803_15397.AA | Ciliate-E2-Unclassified | 10-334 | 22 | 3.6e-54 | 186.29 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 10-334 Range on HMM: 1-352/352 Sequence Identity: 22% (90 aa) YEFISQIGEGTYGTVSKC--SLHGQLLAVKRIK--MDSSSKGVPATTLREVAILKALNAKQ--------RELVEQGKLESLSQANVVNLLDVVYDLSNIF |..| |||.| .|.| || . ..|. | | .| .. ..| . ... ..|..| |. ... . | .. ..|..... | ||. YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQ--ILLNHPHPFIVKMFYCFQDKQNIY LVFEYC-HVDLDQYLKH------------------NVLSPYQIK-----KFMYQLLQGL-SLVHKNEILHRDIKPNNILLAFRGDAGEQLAANASVTTPN .| ||| . || ||.|. . .. .|.| ....|.|||| .| ||| |.||||||.|||. | IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK--------------- PDADNCVLKITDFGLARSYGINVTS---------------ISANVVSLWYR----APELVLASKTYS---TAVDMWSMGCIMYFLANKRALFQVRKDAD- | .||.|||... |. |. . .. .. .. | |||. . . ..|.||.|.|.|.. . |. ... . ----NYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQH ---------------LLQLAFSY-FYVDSSSI-SDLISLPNWNMYVGENQVIDLAALNAPGRKPREVDINIDDVGK----DLFYKLLMLNPSKRISCDEA |.| . ....... . .. .... .| ||. |.| ||.|||. ... QQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQ--------------------------------IPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQI LQHPWF |.|||| LNHPWF |
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Kinase | GL50803_15397.AA | CDK5 | 10-156 | 39 | 3.1e-37 | 114.88 | In-house | 1-135 (287) | Show / Hide |
Range on Protein: 10-156 Range on HMM: 1-135/287 Sequence Identity: 39% (60 aa) YEFISQIGEGTYGTVSKCSLH--GQLLAVKRIKMDSSSKGVPATTLREVAILKALNAKQRELVEQGKLESLSQANVVNLLDVVYDLSNIFLVFEYCHVDL || . ||||||||| | . . | ||...|| |||.| .||...|| | | |.| | ||. . ||||.| || YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHK----------------NIVRLHDVIHSEKKLTLVFEFCDQDL DQYLK--HNVLSPYQIKKFMYQLLQGLSLVHKNEILHRDIKPNNILLAFRG |. ... || ||||||.||.. |....|||| || | | .| KKYMDSCNGEMDMHIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNG |
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Kinase | GL50803_15397.AA | CDK | 176-243 | 44 | 1.3e-33 | 104.78 | In-house | 143-226 (284) | Show / Hide |
Range on Protein: 176-243 Range on HMM: 143-226/284 Sequence Identity: 44% (37 aa) DNCV-----LKITDFGLARSYGI------NVTSISANVVSLWYRAPELVLASKTYS--TAVDMWSMGCIMYFLAN---KRALFQ .| . |||.|||||| .|| .. . .|| |||||||| | ||.|| |..|||| |||.. ... ...||. NNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFP |
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Kinase | GL50803_15397.AA | PCTAIRE | 10-156 | 37 | 1.7e-29 | 101.34 | In-house | 1-134 (291) | Show / Hide |
Range on Protein: 10-156 Range on HMM: 1-134/291 Sequence Identity: 37% (57 aa) YEFISQIGEGTYGTVSKCS--LHGQLLAVKRIKMDSSSKGVPATTLREVAILKALNAKQRELVEQGKLESLSQANVVNLLDVVYDLSNIFLVFEYCHVDL | . ||||| || || | . | | | |... | | | ||| || | ||.| | |... ||||| || YIKLDKLGEGTYATVYKCRSKLTDNLVALKEIRLE-HEEGAPCTAIREVSLLKDLK----------------HANIVTLHDIIHTHHQLTLVFEYMDMDL DQYLKHNV--LSPYQIKKFMYQLLQGLSLVHKNEILHRDIKPNNILLAFRG ||. ... .. .| |..||| || |. ||||| || | |. || KQYMDDCGNIMNMHNVKLFLFQLLRGLAYCHRRKILHRDLKPQNLLINERG |
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Kinase | GL50803_15397.AA | CDK | 81-152 | 37 | 2.2e-29 | 91.06 | In-house | 67-141 (284) | Show / Hide |
Range on Protein: 81-152 Range on HMM: 67-141/284 Sequence Identity: 37% (31 aa) ANVVNLLDVVYDL-----------SNIFLVFEYCHVDLDQYLKHNVLSPYQIKKFMYQLLQGLSLVHKNEILHRDIKPNNILL .|.|.|.||... .....||||.. || .|.. || .|.|||.||. |.| |.|||.||.|||. PNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEYMDHDLKKYMD--------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILI |
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Kinase | GL50803_15397.AA | CDK5 | 177-255 | 48 | 4e-29 | 88.8 | In-house | 134-213 (287) | Show / Hide |
Range on Protein: 177-255 Range on HMM: 134-213/287 Sequence Identity: 48% (39 aa) NCVLKITDFGLARSYGINVTSISANVVSLWYRAPELVLASKTYSTAVDMWSMGCIMYFLA-NKRALFQVRKDADLLQLAF |. || |||||| .|| | |. || ||||.| . ||.||| .||||.|||. .| . | || . | | . | NGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAGRPLFPGNDVEDQLKRIF |
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Kinase | GL50803_15397.AA | PITSLRE | 179-243 | 56 | 9.7e-29 | 101.8 | In-house | 144-208 (295) | Show / Hide |
Range on Protein: 179-243 Range on HMM: 144-208/295 Sequence Identity: 56% (37 aa) VLKITDFGLARSYGINVTSISANVVSLWYRAPELVLASKTYSTAVDMWSMGCIMYFLANKRALFQ .||| |||||| || .. ... .|| |||||||| | .|.|||.||||| |||. . .. ||| ILKICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGCIFAEFITMKPLFQ |
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Kinase | GL50803_15397.AA | CDK4 | 10-153 | 34 | 4.6e-28 | 93.22 | In-house | 1-144 (290) | Show / Hide |
Range on Protein: 10-153 Range on HMM: 1-144/290 Sequence Identity: 34% (54 aa) YEFISQIGEGTYGTVSKC-SLH-GQLLAVKRIKMDSSSK--GVPATTLREVAILKALNAKQRELVEQGKLESLSQANVVNLLDV--VYDLSN----IFLV |. . |||| |||| . .|| |. | |... .. |.| |.||..... |... .|.| |.|| | | | .| YQCVAEIGEGAYGTVYRARDLHTGHFVALKQVRIPIGEEGGGMPMSTIREISVMRHLCQFEH-------------PNIVKLMDVCHVMDTDRAEMKITMV FEYCHVDLDQYLKHNVL---SPYQIKKFMYQLLQGLSLVHKNEILHRDIKPNNILLA || | || .|| .| .||. | ||| |. | . | ||| || |||.. FEHCDWDLHTYLDKCPPPGMPPCTIKHMMHQLLRGVDFLHSHRIIHRDLKPQNILVT |
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Kinase | GL50803_15397.AA | CDK7 | 179-232 | 55 | 3e-27 | 69.24 | In-house | 140-193 (288) | Show / Hide |
Range on Protein: 179-232 Range on HMM: 140-193/288 Sequence Identity: 55% (30 aa) VLKITDFGLARSYGINVTSISANVVSLWYRAPELVLASKTYSTAVDMWSMGCIM .|||.||||||.|| . .|| ||||||| . | |.|||||.|||. QLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIF |
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Kinase | GL50803_15397.AA | CDK7 | 82-157 | 44 | 1.5e-26 | 67.35 | In-house | 63-140 (288) | Show / Hide |
Range on Protein: 82-157 Range on HMM: 63-140/288 Sequence Identity: 44% (35 aa) NVVNLLDVVYDLSNIFLVFEYCHVDLDQYLKHN--VLSPYQIKKFMYQLLQGLSLVHKNEILHRDIKPNNILLAFRGD ||..|.|. .||| |||.. ||. | . .| | || .| ..|||| |.| |||||.|||| |. |. NVIGLIDIFMHKSNIQLVFDFMDWDLEVVIKDKSIILTPAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQ |
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Kinase | GL50803_15397.AA | CDK4 | 180-249 | 47 | 3.4e-21 | 69.3 | In-house | 149-216 (290) | Show / Hide |
Range on Protein: 180-249 Range on HMM: 149-216/290 Sequence Identity: 47% (33 aa) LKITDFGLARSYGINVTSISANVVSLWYRAPELVLASKTYSTAVDMWSMGCIMYFLANKRALFQVRKDAD .|..|||||| |. . . || ||||||| |.| .| | ||||| |||. . . |.|| ..| VKLADFGLARIYS-FQMALTPVVVTLWYRAPEVLLQS-YYNTPVDMWSVGCIFAEMYCRRPLFCGQSEKD |
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Kinase | GL50803_15397.AA | PCTAIRE | 179-242 | 46 | 1.4e-19 | 65.83 | In-house | 135-198 (291) | Show / Hide |
Range on Protein: 179-242 Range on HMM: 135-198/291 Sequence Identity: 46% (30 aa) VLKITDFGLARSYGINVTSISANVVSLWYRAPELVLASKTYSTAVDMWSMGCIMYFLANKRALF .|| |||||| . | ||.|||| |. .. | ||| .||| ||| | .. |.|| ELKLADFGLARAKSVPTKTYSHEVVTLWYRPPDVLMGSTDYSTQIDMWGVGCIFYEMCTGRPLF |
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Kinase | GL50803_15397.AA | CDC2 | 10-63 | 43 | 5.8e-19 | 54.42 | In-house | 1-58 (301) | Show / Hide |
Range on Protein: 10-63 Range on HMM: 1-58/301 Sequence Identity: 43% (25 aa) YEFISQIGEGTYGTVSKCSLH--GQLLAVKRIKMDSSSKG--VPATTLREVAILKALN |. | ||||||| | || .|. |.|.|. .. . | || |..|| .||.|. YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELK |
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Kinase | GL50803_15397.AA | CDK | 10-62 | 36 | 2e-18 | 55.43 | In-house | 1-65 (284) | Show / Hide |
Range on Protein: 10-62 Range on HMM: 1-65/284 Sequence Identity: 36% (24 aa) YEFISQIGEGTYGTVSKCSLHG-------QLLAVKRIKMDS-----SSKGVPATTLREVAILKAL || . .|||||||.| |. . |. | |.|.|.. |.| |..||...|| | YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL |
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Kinase | GL50803_15397.AA | CDK | 267-334 | 25 | 8.8e-16 | 46.81 | In-house | 251-284 (284) | Show / Hide |
Range on Protein: 267-334 Range on HMM: 251-284/284 Sequence Identity: 25% (17 aa) DLISLPNWNMYVGENQVIDLAALNAPGRKPREVDINIDDVGKDLFYKLLMLNPSKRISCDEALQHPWF .. .||.. || |.|...|.||||...|||||.| GVTKLPDY----------------------------------DLLNKMLCYDPKKRISAEQALQHPYF |
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Kinase | GL50803_15397.AA | CDC2 | 295-334 | 45 | 1.5e-14 | 40.61 | In-house | 263-301 (301) | Show / Hide |
Range on Protein: 295-334 Range on HMM: 263-301/301 Sequence Identity: 45% (18 aa) KPREVDINIDDVGKDLFYKLLMLNPSKRISCDEALQHPWF |... . .|. | || ..| ..|.|||| .||||||.| KKKNQ-SCLDPEGIDLLMQMLQYDPQKRISAKEALQHPYF |
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Kinase | GL50803_15397.AA | CDK7 | 10-60 | 38 | 8.7e-14 | 32.67 | In-house | 1-57 (288) | Show / Hide |
Range on Protein: 10-60 Range on HMM: 1-57/288 Sequence Identity: 38% (22 aa) YEFISQIGEGTYGTVSKCS--LHGQLLAVKRIK----MDSSSKGVPATTLREVAILK || |..||||...||.| .|| |.|.|| . |. | .||. ||. YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQ |
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Kinase | GL50803_15397.AA | CDK5 | 302-334 | 48 | 3.5e-13 | 37.53 | In-house | 255-287 (287) | Show / Hide |
Range on Protein: 302-334 Range on HMM: 255-287/287 Sequence Identity: 48% (16 aa) NIDDVGKDLFYKLLMLNPSKRISCDEALQHPWF . | | || |.|..|| .||| ..||.||.| KLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF |
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Kinase | GL50803_15397.AA | CDK7 | 309-334 | 38 | 5.5e-12 | 27.78 | In-house | 263-288 (288) | Show / Hide |
Range on Protein: 309-334 Range on HMM: 263-288/288 Sequence Identity: 38% (10 aa) DLFYKLLMLNPSKRISCDEALQHPWF || ... .||.||..| ..|..| | DLMCGMWTMNPCKRWTCTQCLKMPYF |
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Kinase | GL50803_15397.AA | TyrKc | 10-269 | 17 | 6.4e-12 | -29.97 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 10-269 Range on HMM: 1-280/280 Sequence Identity: 17% (58 aa) YEFISQIGEGTYGTVSKCSLHGQLLAVKRIKMDSSSKGVPATTLREVAILKAL--NAKQRELVEQGKLESLSQANVVNLLDVVYDL-------SNIFLVF ... ..||| .|.| |. . . ||| .| |. . .|| |.. | . . |.|.|. |. . ...|. ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHP----------------NIVRLYGVCTQQGRNFMYIEPLMIVM EYC-HVDLDQYLKHNV--LSPYQIKKFMYQLLQGLSLVHKNEILHRDIKPNNILLAFRGDAGEQLAANASVTTPNPDADNCVLKITDFGLARSYGIN--- ||. | ||..||. . |.. . .|..| .| . |.. . |||. |.|.. .. . ||.||||.| . EYMPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----------------------TVKISDFGLSRDIYDDDQQ -----VTSI----SAN-VVSLWYRAPELVLASKTYSTAVDMWSMGCIMY----------------FLANKRALFQVRKD--ADLLQL--------AFSYF . . ... .. . ||| .. ....|. | || | |. .. |.... .|.. . . . . GESKDYYRKKEHKGGKTMLPIRWMAPE-CINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEM YV--------------DSSSISDLI | | | ... YQIMKQCWHEDPEDRPTFSEIHECF |
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Kinase | GL50803_15397.AA | PITSLRE | 303-334 | 50 | 1.9e-11 | 38.12 | In-house | 264-295 (295) | Show / Hide |
Range on Protein: 303-334 Range on HMM: 264-295/295 Sequence Identity: 50% (16 aa) IDDVGKDLFYKLLMLNPSKRISCDEALQHPWF | |.| || ..| .|| .||. ..||.|||| ISDTGFDLLNQMLTYNPKNRITASDALKHPWF |
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Kinase | GL50803_15397.AA | PITSLRE | 10-63 | 37 | 4.9e-11 | 36.6 | In-house | 1-59 (295) | Show / Hide |
Range on Protein: 10-63 Range on HMM: 1-59/295 Sequence Identity: 37% (22 aa) YEFISQIGEGTYGTVSKCS--LHGQLLAVKRIKMD--SSSKGVPATTLREVA-ILKALN .. . .|.||||| |.. . . | ||.||. | | | |||. ||.||. FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQ |
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Kinase | GL50803_15397.AA | CDK4 | 294-334 | 36 | 7e-09 | 26.38 | In-house | 250-290 (290) | Show / Hide |
Range on Protein: 294-334 Range on HMM: 250-290/290 Sequence Identity: 36% (15 aa) RKPREVDINIDDVGKDLFYKLLMLNPSKRISCDEALQHPWF |..... .. |.|| | | |..||.| ..||||.| RPFKDFCPHMCKQGDDLLQKMLCYNHHKRMSAYQCLQHPYF |
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Kinase | GL50803_15397.AA | PCTAIRE | 307-334 | 35 | 2.3e-07 | 22.0 | In-house | 264-291 (291) | Show / Hide |
Range on Protein: 307-334 Range on HMM: 264-291/291 Sequence Identity: 35% (10 aa) GKDLFYKLLMLNPSKRISCDEALQHPWF . || .|| . . .|.| ..|..||.| CQDLLTMLLQYESKNRVSAEKAMKHPYF |
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Kinase | GL50803_15397.AA | PITSLRE | 82-156 | 34 | 2.5e-07 | 22.96 | In-house | 62-143 (295) | Show / Hide |
Range on Protein: 82-156 Range on HMM: 62-143/295 Sequence Identity: 34% (28 aa) NVVNLLDVV--YDLSNIFLVFEYCHVDLDQYL-KHN----VLSPYQIKKFMYQLLQGLSLVHKNEILHRDIKPNNILLAFRG |.||.. .| .. |..|.|| || . ... .| .|| .| ||| | . |.| |.||| | |.|. | NIVNVKEIVMGSNMDKIYMVMEYVEHDLKSLMENMKRRNQPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKG |
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Kinase | GL50803_15397.AA | Pkinase_Tyr | 82-189 | 26 | 0.000164 | 15.9 | Pfam | 65-159 (270) | Show / Hide |
Range on Protein: 82-189 Range on HMM: 65-159/270 Sequence Identity: 26% (31 aa) NVVNLLDVVY-DLSN--IFLVFEYC-HVDLDQYLKHN-----VLSPYQIKKFMYQLLQGLSLVHKNEILHRDIKPNNILLAFRGDAGEQLAANASVTTPN |.|.|. |.. . |..|.||. | ||. ||. . |.. .. .. .| .|.. . . . |||. |.|.. NIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVT------------------- PDADNCVLKITDFGLAR .| | ||.|||||| ---ENNVVKICDFGLAR |
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Kinase | GL50803_15397.AA | Pkinase_Tyr | 10-46 | 25 | 0.000887 | 13.42 | Pfam | 1-43 (270) | Show / Hide |
Range on Protein: 10-46 Range on HMM: 1-43/270 Sequence Identity: 25% (11 aa) YEFISQIGEGTYGTVSKCSLH------GQLLAVKRIKMDSSSK .|. ..||| .|.| |. .. .. ||| .| ..... ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHE |