Gene 92043.m00144 (T.vaginalis)

92043.m00144

Species: T.vaginalis
Alias: 92043.m00144, TvagK0604
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CDC2

Sequence

Name Sequence Type Origin Length Description Download
92043.m00144.AA Protein None 300 None Fasta, JSON
92043.m00144.kin_dom Protein Kinase Domain None 278 None Fasta, JSON

Protein domain

Protein domains of 92043.m00144.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 92043.m00144.AA CDC2 7-284 44 8.70000000001e-128 395.0 In-house 1-301 (301) Show / Hide 
Range on Protein: 7-284
Range on HMM: 1-301/301
Sequence Identity: 44% (134 aa)

YTKLEKLGEGGFGSVYRAKDEVNNNIVSMKVIPLDMEIDG--ITSSCLREISAMKAFD-HPNIVKCLNTIVTSEKAVIISEFMEMSLRKFLCMKSP----
|.|.||.||| .| ||..||   | || .| | |. | .|  . |...|||| .|. . ||||||    |.   |  .. |...| |.|.. |. |    
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNKH

MDPELVRSYSYQMLCGIAYMHSHHYLHRDIKPENLLINRTGMLKIADFSLARSFGIPLTQMT--PNVTTLWYRPPEIVLGSTFYDIGIDSWSAGCVIAEM
|.|.||.|| ||.| |... |..  .|||.|| |.||...| .||||| ||| ||||. . |   .| |||||.||| ||. .|....| || ||..|||
MPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEM

---IKKSPLFVGDSDLDQAFGIFKILGTP-EEYWPENAVIS--ADVFPEMEKKDLGGVLNI---------QDPDLIDLITKLLSIDPNKRLTARDALDHP
   . | ||| |||  || | ||.||||| |. ||.          ||. ...||  ..            ||. |||. ..| .||.||..|..||.||
FMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQHP

YF
||
YF
Kinase 92043.m00144.AA CMGC 7-284 23 3.9e-111 366.59 In-house 1-513 (513) Show / Hide 
Range on Protein: 7-284
Range on HMM: 1-513/513
Sequence Identity: 23% (120 aa)

YTKLEKLGEGGFGSVYRAKD--------------EVNNNIVSMKVIPLD-MEID--------GITSSCLREISAMKAF-----------------DHPNI
|....|.||| .| ||...|                .|.|| .| | .. .|..        |. ...||||. .| .                 .|.||
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VKCLNTIVTSE-----------------KAVIISEFMEMSLRKFLCMKS---------PMDPEL------------VRSYS------YQMLCGIA--YMH
||... .....                 .  .. |.|...| ... ...         |...              .....      ||.|.|..  |.|
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

SHH--YLHRDIKPENLLINRT--------------------GMLKIADFSLARSFGIP---------------------LTQMTPNVTTLWYRPPEIVLG
||    .|||.||||.||| .                    | |||.|| |||.....                     . ..|..| |.|||.||| ||
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

S---------TFYDIGIDSWSAGCVIAEMIKK--------SPLFVGDSD-----------LDQAFGIFKILGTP----------------EEYWPENAV-
.         . |. .|| ||.||..|||. .         ||| |.|.           .|| | |||.||||                || ||.    
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKL

------------------ISADV---------FPEMEKKDLGGVLNI-----------------------------------QDPDLIDLITKLLSIDPN
                  .| ..         ||.  .|..  .                                      .||..|||. |.| .||.
PWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPD

KRLTARDALDHPYF
||.|| .||.||||
KRITAEQALQHPYF
Kinase 92043.m00144.AA CDK 7-284 38 6.9e-108 346.29 In-house 1-284 (284) Show / Hide 
Range on Protein: 7-284
Range on HMM: 1-284/284
Sequence Identity: 38% (121 aa)

YTKLEKLGEGGFGSVYRAKDEVNN-----NIVSMKVIPLDM-----EIDGITSSCLREISAMKAFDHPNIVKCLNTIVTS-----------EKAVIISEF
| ||||.||| .| ||.|.|  ..     .|| .| | ..      | .|. .. .|||| .|   |||||| .  ..|.            | ... |.
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

MEMSLRKFLCMKSPMDPELVRSYSYQMLCGIAYMHSHHYLHRDIKPENLLINRTGM-----LKIADFSLARSFGI------PLTQMTPNVTTLWYRPPEI
|.. | |..          ...| .|.| |..|.||.. .|||.|| |.|||..|      |||||| ||| |||      |.  .|..| |||||.||.
MDHDLKKYMD---------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPEL

VLGSTFYD--IGIDSWSAGCVIAEMIK---KSPLFVGDSDLDQAFGIFKILGTP-EEYWPENAVISADVFPEMEKKDLGGVLNIQDPDLIDLITKLLSID
 |||. |.   .|| ||.||..|||.    . ||| |||..|| | ||.|.||| |. ||.                             ||. |.|  |
LLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY----------------------DLLNKMLCYD

PNKRLTARDALDHPYF
|.||..| .||.||||
PKKRISAEQALQHPYF
Kinase 92043.m00144.AA CDK5 7-284 41 2.3e-106 337.13 In-house 1-287 (287) Show / Hide 
Range on Protein: 7-284
Range on HMM: 1-287/287
Sequence Identity: 41% (120 aa)

YTKLEKLGEGGFGSVYRAKDEVNNNIVSMKVIPLDMEIDGITSSCLREISAMKAFDHPNIVKCLNTIVTSEKAVIISEFMEMSLRKFL-CMKSPMDPELV
| |.||.||| .| ||.|..     || .| . || |  |. |. .|||. .|   |.|||     | .  | ... ||.   |.|..  ..  ||....
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEKKLTLVFEFCDQDLKKYMDSCNGEMDMHII

RSYSYQMLCGIAYMHSHHYLHRDIKPENLLINRTGMLKIADFSLARSFGIPLTQMTPNVTTLWYRPPEIVLGSTFYDIGIDSWSAGCVIAEMI-KKSPLF
.|. ||.| |.|. |.|| |||| || |||||. | || ||| ||| ||||    .  | ||||||| . .||  |   || ||.||..|||.    |||
KSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAGRPLF

VGDSDLDQAFGIFKILGTP-EEYWPENAVISADV-----FPEMEKKD-LGGVLNIQDPDLIDLITKLLSIDPNKRLTARDALDHPYF
 | .. || . ||||.||| |. ||  .  .        .|  . .  .  .    |  . ||  |.| ..||.|..| .|| ||||
PGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase 92043.m00144.AA CDK7 7-284 36 1.1e-92 247.11 In-house 1-288 (288) Show / Hide 
Range on Protein: 7-284
Range on HMM: 1-288/288
Sequence Identity: 36% (106 aa)

YTKLEKLGEGGFGSVYRAKDEVNNNIVSMKVIP----LDMEIDGITSSCLREISAMKAFDHPNIVKCLNTIVTSEKAVIISEFMEMSLRKFLCMKS-PMD
|.|....||| |. ||.| | . . ||  | |      .   |||  . .|||   .   |.|..  .  .        . .||.  |      ||  . 
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKSNIQLVFDFMDWDLEVVIKDKSIILT

PELVRSYSYQMLCGIAYMHSHHYLHRDIKPENLLINRTGMLKIADFSLARSFGIPLTQMTPNVTTLWYRPPEIVLGSTFYDIGIDSWSAGCVIAEMIKKS
|  . .|  ..| |. |.| .  ||||.|| |||.|  | |||||| |||..| |    |..| | ||| ||   |   |  |.| || ||..|| .   
PAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELMLRV

PLFVGDSDLDQAFGIFKILGTP-EEYWPE----NAVISADVFPEMEKKDLGGVLNIQDPDLIDLITKLLSIDPNKRLTARDALDHPYF
| . ||||.||   ||..|||| || ||.    .  |    ||.  .  |  .      ||.||. ...  .| ||.|....| .|||
PYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDYIKFKDFPGYSRTPLRHIFTAASDDLLDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase 92043.m00144.AA S_TKc 7-284 28 2.1e-84 287.65 SMART 1-231 (231) Show / Hide 
Range on Protein: 7-284
Range on HMM: 1-231/231
Sequence Identity: 28% (85 aa)

YTKLEKLGEGGFGSVYRAKDEVNNNIVSMKVIPLDMEIDGITSSCLREISAMKAFDHPNIVKCLNTIVTSEKAVIISEFMEM---SLRKFLCMKSP----
|..|.|.|.|.||.||....   . || .|.|.          . .|||. .|  .||||||.. .... ..  .. |...    .|..... . .    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--MDPELVRSYSYQMLCGIAYMHSHHYLHRDIKPENLLINRTGMLKIADFSLARSFGIPLTQMTPNVTTLWYRPPEIVLGSTFYDI-GIDSWSAGCVIAE
  ...  .|.| ||..|...|.|||. .|||.||||.|...   .||.|| ||| .       |  . |.||..||..     |.   .| || ||...|
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYE

MIKKSPLFVGDSDLDQAFGIFKILGTPEEYWPENAVISADVFPEMEKKDLGGVLNIQDPDLIDLITKLLSIDPNKRLTARDALD-------HPYF
|.   |.|       | . .||..|                                .|...|.| |.|  ||.||.|| .||        ||.|
MLCGYPPFP------QMQMMFKKIG--------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 92043.m00144.AA Pkinase 7-284 29 5.1e-80 276.94 Pfam 1-293 (293) Show / Hide 
Range on Protein: 7-284
Range on HMM: 1-293/293
Sequence Identity: 29% (89 aa)

YTKLEKLGEGGFGSVYRAKDEVNNNIVSMKVIPLDMEIDGITSSCLR--EISAMKAFDHPNIVKCLNTIVTSEKAVIISEFMEM-----SLRKFLC--MK
|....|.|.|.||.||....  .. || .|.|... | ..   . .|  ||. || ..|||||... .  .. .  .. |..|.     .|  ..   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

SPM--DPELVRSYSYQMLCGIAYMHSHHYLHRDIKPENLLINRTGML----KIADFSLARSF-GIPLTQMTPNVTTLWYRPPEIVLGSTFYDIGIDSWSA
 ..  ... ...| ||.|.|..|.||.  .|||.||||.||...| .    ||.|| ||. |   . . ||  . |.||..||...|.. |.  .| ||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GCVIAEMIKKSPLFVGD----SDLDQAFGIFKILG----TPEEYWPENAVISADVFPEMEKKDLGGVLNIQDPDLIDLITKLLSIDPNKRLTARDALDHP
||...||. . |.| |.    . .|| . |..|.|     ....| ..   . . . . . . .  .   ......|.|...|  ||.||.||...| ||
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHP

YF
.|
WF
Kinase 92043.m00144.AA MAPK 7-284 31 4e-77 262.52 In-house 1-328 (328) Show / Hide 
Range on Protein: 7-284
Range on HMM: 1-328/328
Sequence Identity: 31% (103 aa)

YTKLEKLGEGGFGSVYRAKDEV------NNNIVSMKVIP--LDMEIDGITSSCLREISAMKAF-DHPNIVKCLNTIVTSE----KAV-------IISEFM
|. |...|.| .| |  |.|        ....|  | |.   . ...      .|||  .. | .|.||.| |. .  ..    .         |..|.|
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCK--RTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELM

EMSLRKFLCMKSPMDPELVRSYSYQMLCG--IAYMHSHHYLHRDIKPENLLINRTGMLKIADFSLARSFGIPLT--------------QMTPNVTTLWYR
|  |.. . .  |.. . ...  ||.|.|  . |.||   .|||.||.|.|.|  . |||.|| ||||.    .              .||..|.| |||
ETDLHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYR

PPEIVLG--STFYDIGIDSWSAGCVIAEMIK-KSPLFVGDSDLDQAFGIFKILGTPEEYWPENAV--ISA-----DV--FPEMEKKDLGGVLN----IQD
 ||| |.  .. |. ..| ||.||  |||..   ||| |.. .|| . |...||||.|   ..     .|         .| . ||..  ..     . .
APEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNAN

PDLIDLITKLLSIDPNKRLTARDALDHPYF
|. |||. |.| .||.||.|. .|| ||||
PQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase 92043.m00144.AA CDK4 7-284 35 9.2e-71 241.4 In-house 1-290 (290) Show / Hide 
Range on Protein: 7-284
Range on HMM: 1-290/290
Sequence Identity: 35% (103 aa)

YTKLEKLGEGGFGSVYRAKDEVNNNIVSMKVIPLDMEID--GITSSCLREISAMK---AFDHPNIVKCLNTIVTSEKAV------IISEFMEMSLRKFL-
| ..  .||| .| |||| |  . ..|  | .   .. .  |.  | .|||| |.   .|.|||||| .    ...         .. |  .  |. .| 
YQCVAEIGEGAYGTVYRARDLHTGHFVALKQVRIPIGEEGGGMPMSTIREISVMRHLCQFEHPNIVKLMDVCHVMDTDRAEMKITMVFEHCDWDLHTYLD

-CMKSPMDPELVRSYSYQMLCGIAYMHSHHYLHRDIKPENLLINRTGMLKIADFSLARSFGIPLTQMTPNVTTLWYRPPEIVLGSTFYDIGIDSWSAGCV
 | .. | |. ..  . |.| |. . |||   ||| ||.|.|... | .|.||| ||| ..   . .|| | ||||| ||. | |. |   .| ||.||.
KCPPPGMPPCTIKHMMHQLLRGVDFLHSHRIIHRDLKPQNILVTSDGHVKLADFGLARIYSF-QMALTPVVVTLWYRAPEVLLQSY-YNTPVDMWSVGCI

IAEMIKKSPLFVGDSDLDQAFGIFKILGTP-EEYWPENAVISADVFPEMEKKDLGGVLNIQDPDLIDLITKLLSIDPNKRLTARDALDHPYF
.||| .  |||.| |. ||   ||.. |.| |. ||   ..  | ||    . .  .    .   .||. | |. .. ||..|. .| ||||
FAEMYCRRPLFCGQSEKDQLHKIFDVMGLPPEDDWPRDVSLPWDHFPQRHPRPFKDFCPHMCKQGDDLLQKMLCYNHHKRMSAYQCLQHPYF
Kinase 92043.m00144.AA PFTAIRE 7-284 38 6.4e-66 225.31 In-house 1-287 (287) Show / Hide 
Range on Protein: 7-284
Range on HMM: 1-287/287
Sequence Identity: 38% (111 aa)

YTKLEKLGEGGFGSVYRAKDEVNNNIVSMKVIPLDMEIDGITSSCLREISAMKAFDHPNIVKCLNTIVTSEKAVIISEFMEMSLRKFL-CMKSPMDPELV
| |||||||| .  ||...  .|. .| .|.| |. |  |      || | .|   | |||     | | |   .. |...  | ...      |.|. |
YEKLEKLGEGSYATVYKGISCINQQFVALKEIRLQQE-EGTPFTAIREASLLKNLKHANIVCLHDIIHTKETLTFVFEYVHTDLCQYMDKHPGGMHPNNV

RSYSYQMLCGIAYMHSHHYLHRDIKPENLLINRTGMLKIADFSLARSFGIPLTQMTPNVTTLWYRPPEIVLGSTFYDIGIDSWSAGCVIAEMIKKSPLFV
| . .|.| | .| |  . ||||.|| ||||  .| || ||| |||   .|       | ||||||| . |||| |   .| | .||.  ||..  |.| 
RLFLFQLLRGLSYCHQRRVLHRDLKPQNLLISHCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTHLDMWGVGCIFVEMMWGQPAFP

GD-SDLDQAFGIFKILGTP-EEYWPENAVISADVF-PEMEK------KDLGGVLNIQD--PDLIDLITKLLSIDPNKRLTARDALDHPYF
|    .||   |||.|||| |. ||   | .   . |.  .      | |. ...  .  |.  ||..|.| . | .|. | .|. ||||
GMKDITDQLEKIFKVLGTPTEDTWP--GVCHLPNYKPHWFRGRFYKPKKLCHQWPRIYYIPHAEDLMMKMLQCEPRDRVSAQEAMQHPYF
Kinase 92043.m00144.AA PITSLRE 7-225 39 1.5e-62 214.14 In-house 1-228 (295) Show / Hide 
Range on Protein: 7-225
Range on HMM: 1-228/295
Sequence Identity: 39% (91 aa)

YTKLEKLGEGGFGSVYRAKDEVNNNIVSMKVIPLD--MEIDGITSSCLREIS-AMKAFDHPNIVKCLNTIV--TSEKAVIISEFMEMSLRKFL-CMK---
. .| . .|| .| ||||||   . || .| . ..   | .|.    ||||.   .|  |||||. .  ..  .  |  .. |..|  |.  .  ||   
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVNVKEIVMGSNMDKIYMVMEYVEHDLKSLMENMKRRN

SPMDPELVRSYSYQMLCGIAYMHSHHYLHRDIKPENLLINRTGMLKIADFSLARSFGIPLTQMTPNVTTLWYRPPEIVLGSTFYDIGIDSWSAGCVIAEM
 |  |  . .   | | |...||..  .||| |  |||..  |.|||.|| ||| .| |.   ||.| ||||| ||. ||.  |   .| || ||. ||.
QPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGCIFAEF

IKKSPLFVGDSDLDQAFGIFKILGTPEE
| . ||| |.|..||   ||| .||| |
ITMKPLFQGKSEIDQINCIFKEMGTPTE
Kinase 92043.m00144.AA GSK 169-284 34 2.8e-39 117.21 In-house 184-328 (328) Show / Hide 
Range on Protein: 169-284
Range on HMM: 184-328/328
Sequence Identity: 34% (50 aa)

YRPPEIVLGSTFYDIGIDSWSAGCVIAEMIKKSPLFVGDSDLDQAFGIFKILGTPEE----YWPENA--VISA-----DVFPEMEKK-------------
||.||  .|.| |.  || ||.|||.|||.|  ||| ||| .||.. |.|.|||| .    .. ..   .         ..|  ..|             
YRAPELIFGCTNYTCQIDVWSCGCVMAEMLKGQPLFPGDSSVDQLVEIIKMLGTPTKEQIQSMNPSYPEFKFPYWSFQQIKPHPWQKNDTKYEYQTYYHK

-----DLGGVLNIQDPDLIDLITKLLSIDPNKRLTARDALDHPYF
      .  ... ...|.||||.|.| .||.|||....|. ||.|
KYRTVYMFKWCHTDMQDWIDLISKCLVYDPKKRLSPLEACAHPFF
Kinase 92043.m00144.AA GSK 7-147 33 1.7e-34 102.32 In-house 1-161 (328) Show / Hide 
Range on Protein: 7-147
Range on HMM: 1-161/328
Sequence Identity: 33% (56 aa)

YTKLEKLGEGGFGSVYRAKDE----VNNNI----VSMKVIPLDMEIDGITSSCLREISAMKAF---DHPNIVKCLNTIVTS-EK----AVIIS----EFM
|.  .. | | || ||.|..      .. |    |  | .  | .       | ||   ||     ||||||....   .. ||     |..     |.|
YEEMKVIGHGSFGVVYQAYMNSPSNETKEIWLGPVAIKKVWQDKRYK-----CNRELQIMKMLGKLDHPNIVRLKYFFYMHYEKKDENHVYCNCLVMEYM

EMSLRKFLCM----KSPMDPELVRSYSYQMLCGIAYMHSHHYLHRDIKPENLLIN-RTGMLKIADF
.. | ...      | .|.  ... |.|||..|.|| |||   ||||||.|.|.. .|| |||.||
PQTLYQVIRHYVKNKQQMPIIHIKLYMYQMFRGLAYLHSHGICHRDIKPQNILVDPDTGVLKICDF
Kinase 92043.m00144.AA Pkinase_Tyr 52-151 30 5.9e-16 54.67 Pfam 51-159 (270) Show / Hide 
Range on Protein: 52-151
Range on HMM: 51-159/270
Sequence Identity: 30% (33 aa)

LREISAMKAF-DHPNIVKCLNTIV-TSEK--AVIISEFMEM-SLRKFLCM----KSPMDPELVRSYSYQMLCGIAYMHSHHYLHRDIKPENLLINRTGML
.||.. || . .|||||...  ..  .|     |. |.|.  .|...|      | | ...   ....|  .| .| .|... |||.   | |.....  
MREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVV

KIADFSLAR
||.|| |||
KICDFGLAR
Kinase 92043.m00144.AA TyrKc 7-284 19 2.7e-13 -7.69 SMART 1-280 (280) Show / Hide 
Range on Protein: 7-284
Range on HMM: 1-280/280
Sequence Identity: 19% (62 aa)

YTKLEKLGEGGFGSVYRAKDEVNNNIVSMKVIPLDMEIDGITSSCLREISAMKAF--DHPNIVKCLNTIVTS-------EKAVIISEFMEM-SLRKFLCM
 |...||||| || ||...       |  |..  |          .||.. |. .  .|||||...  ....       |   |. |.|.  .|...|  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

KSP-MDPELVRSYSYQMLCGIAYMHSHHYLHRDIKPENLLINRTGMLKIADFSLARSFGIP-------LTQMT-----PN--VTTLWYRPPEIVLGSTF-
. |   ..   |...|  || .| ||... |||.   | |... .  ||.|| |.|  .          . ..      .  .   |. .||     .  
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM-APECI--NYGK

YDIGIDSWSAGCV---IAEMIKKSPLF-----VGDSDLDQAFGIFKILGTPEEYWPENAVISADVFPEMEKKDLGGVLNIQDPDLIDLITKLLSIDPNKR
. .  | || | .   |    .. .       . .... .     . .  |...      .|                 .  ... .....    ||..|
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY---P-MS--------------F-VCCPDEMYQIMKQCWHEDPEDR

LTARDALDHPYF
 | ..   | .|
PTFSEI--HECF
Kinase 92043.m00144.AA PITSLRE 259-284 50 2.5e-10 34.0 In-house 270-295 (295) Show / Hide 
Range on Protein: 259-284
Range on HMM: 270-295/295
Sequence Identity: 50% (13 aa)

DLITKLLSIDPNKRLTARDALDHPYF
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DLLNQMLTYNPKNRITASDALKHPWF
Kinase 92043.m00144.AA Pkinase_Tyr 7-25 52 0.005268 10.8 Pfam 1-19 (270) Show / Hide 
Range on Protein: 7-25
Range on HMM: 1-19/270
Sequence Identity: 52% (10 aa)

YTKLEKLGEGGFGSVYRAK
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ITFGKKLGEGAFGEVYKGT