Gene 84458.m00209 (T.vaginalis)

84458.m00209

Species: T.vaginalis
Alias: TvagK0040, 84458.m00209
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
84458.m00209.AA Protein None 386 None Fasta, JSON
84458.m00209.kin_dom Protein Kinase Domain None 251 None Fasta, JSON

Protein domain

Protein domains of 84458.m00209.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 84458.m00209.AA CAMK 22-267 23 3.8e-109 352.95 In-house 1-425 (425) Show / Hide 
Range on Protein: 22-267
Range on HMM: 1-425/425
Sequence Identity: 23% (98 aa)

AVGRGAFGTVKVAYRP-DNG-----------KYYACKIITKHTIDS-------------------------MIDKSKFEKEIRIMQQ-------LHSPRI
  |||.||.|| ...  ..|           . .|.||| |  ...                           |. ....||.||..       |. | |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQLFDLLKD-------------------TMNYYIVT---ELCTGG----DMFQQILQN---------------KKIPEERAKIYAKQLLEAISYIHKLNV
..|..   |                   ....|.|.   |.|.||    |.|. | ..               ....|. |. | .|...|. |.|..|.
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

CHRDLKPENILLDNN-----------------GDIKLSDFGFSKFIDG--------------------------LTHTSCGSYVYAA-PEILEG------
.||||||||||||.|                 ..||..||||....|.                          . .|.||.  |.| ||.|.|      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------TDYDPKKSDIWAVGVIIYAMVTGQLPWTKR-------------NQHELSKQIKACQYK-IPQD-----------------------LSEECLS
        .|...|.|.|..||| |.|..| .|.                |..|| ..|....|  .|                         .|.|| .
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

VITGILQREPEDRPSADELLKSPWL
 | ..||..||.|..... |. ||.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 84458.m00209.AA AGC 17-267 23 3.6e-104 269.66 In-house 1-395 (395) Show / Hide 
Range on Protein: 17-267
Range on HMM: 1-395/395
Sequence Identity: 23% (93 aa)

YQLQNAVGRGAFGTVKVAYRP------DNGKYYACKIITKHT---IDS--MIDKSK----------FEKEIRIMQQLH----------SPRIVQ-LFDLL
...   .|.|.||.|  . .       |.|||||.|.. | .   |.   |... .          . .| .|.....          .| ||. |.   
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

KDTMN--YYIVTELCT---------GG-DMFQQIL---QNKKIPEERAKIYAKQ-------LLEAISYIHK-LNVCHRD-LKPENILLDNNGDIKLSDFG
.|  .   |.| |..          || ..|...    .... .||||..|| .       .. |. |.|. ... ||| |||||||||..| |||.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

FSKFIDG-----------------------------------------------------LTHTSCG--SYVYAAPEILEGTDYDPKKSDIWA--VGVII
..| . .                                                     .|.| ||  .  | |||||    |. |  |.|.  .|...
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YG-KACDWWSFGLGCLM

YAMVTGQLPWTKRN----------QHELSKQIK------ACQYKIP----------QDLSEECLSVITGILQREPEDRPS----------ADELLKSPWL
| |.||. | .  |          ..|. ..|.       .. |.|          . .|.|. . |.. |...||.|.           |.|. . || 
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 84458.m00209.AA CAMKL 17-267 34 5.5e-99 316.53 In-house 1-297 (297) Show / Hide 
Range on Protein: 17-267
Range on HMM: 1-297/297
Sequence Identity: 34% (102 aa)

YQLQNAVGRGAFGTVKVAYR-PDNGKYYACKIIT--KHTIDSMIDKS----------KFEKEIRIMQQLH---SPRIVQLFDLLKDTMN------YYIVT
|..    |.|.||.|| |     .|. .| |||   | . |  ..|           . ..||.||..|.    | |..|.. . .  .      .|.|.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELCTGGD--MFQQILQN----KKIPEERAKIYAKQLLEAISYIHKLNVCHRDLKPENILLDNNGD--IKLSDFGFSKF---I----DGLTHTSCGSYVYA
|.| ||.  .|. | ..    ...||. |. | .|...|..|.|.....|||.||||||||.||.  ||..||||| .   .    . . .|.|||. |.
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEILEG--TDYDPKKSDIWAVGVIIYAMVTGQLPWTKR--------NQHELSKQIKACQYKIP--QDLSEECLSVITGILQREPEDRPSADELLKSPWL
||||..|  ..|| .| |||. ||| ||||.|.||.           |. .| ..|. . |..|   ..| .| . | ..||. ||.||....... ||.
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
S_TKc 84458.m00209.AA S_TKc 17-267 33 2.5e-97 330.55 SMART 1-231 (231) Show / Hide 
Range on Protein: 17-267
Range on HMM: 1-231/231
Sequence Identity: 33% (90 aa)

YQLQNAVGRGAFGTVKVAYRPDNGKYYACKIITKHTIDSMIDKSKFEKEIRIMQQLHSPRIVQLFDLLKDTMNYYIVTELCTG--GDMFQQILQNKK---
|.. . .|.||||.|. ..  . |...|.|||            ....||.|... | | ||.|.|   |  ..|.|.|.| |  ||.|. | ....   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---IPEERAKIYAKQLLEAISYIHKLNVCHRDLKPENILLDNNGDIKLSDFGFSKFIDGLTHTSCGSYVYAAPEILEGTDYDPKKSDIWAVGVIIYAMVT
   .|| .|. |..|...|. |.|.....||||||||||||.   ||..|||.....    .| ||.  | |||.|    |...|.|.|..|.|.| |..
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

GQLPWTKRNQHELSKQIKACQYKIPQDLSEECLSVITGILQREPEDRPSADELLK-------SPWL
|. |.   ..... |.|.          |.|... | ..||..||.||.| |.|.        ||.
GYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase 84458.m00209.AA Pkinase 17-267 31 2.3e-94 324.61 Pfam 1-293 (293) Show / Hide 
Range on Protein: 17-267
Range on HMM: 1-293/293
Sequence Identity: 31% (93 aa)

YQLQNAVGRGAFGTVKVAYRPDNGKYYACKIITKHTIDSMIDKSKFE-KEIRIMQQLHSPRIVQLFDLLKDTMNYYIVTELCTGG----DMFQQILQ---
|..   .|.|.||.|. ... ..|| .|.||| |....|  |....   ||.||. |..| ||.|.|   |  ..|.|.|.| ||    | |  ...   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLF-DYISTWR

NKKI--PEERAKIYAKQLLEAISYIHKLNVCHRDLKPENILLDNNGDI----KLSDFGFSKFI---DGLTHTSCGSYVYAAPEILEGTDYDPKKSDIWAV
....  .|. .| |..|.|... |.|. ...||||||||||.||||.|    |..|||..|..   .. ..| ||.. |.|||.. |  |...|.|.|..
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDYNNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVIIYAMVTGQLPWTKR------NQHELSKQIKACQYKIPQDLS---------------------EECLSVITGILQREPEDRPSADELLKSPWL
|.|.| |..|..|.  .      .| .. ..|. .... . . .                     |||...|...|.. |..||.|...|..||.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 84458.m00209.AA MARK 17-267 35 3.7e-90 294.9 In-house 1-262 (262) Show / Hide 
Range on Protein: 17-267
Range on HMM: 1-262/262
Sequence Identity: 35% (94 aa)

YQLQNAVGRGAFGTVKVAYRPDNGKYYACKIITKHTIDSMIDKSKFEKEIRIMQQLHSPRIVQLFDLLK--DTMN-YYIVTELCTGGDMFQQILQN--KK
| .    | |....||.|     |. .| ||. |  ..    ..... ||.||..|. | |..||.     .. .  |.. |.. ||.... | .    .
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

IPEERAKIYAKQLLEAISYIHKLNVCHRDLKPENILLDNNG--DIKLSDFGFSKFI--DGLTHTSCGSYVYAAPEILEGTDYDPKKSDIWAVGVIIYAMV
..|| |. . .|...|..| |. |..|||.||||||.| ||  .||..|||||  |  . .  | ||.. |.||||... .|| .| |||. ||. |.||
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

TGQLPWTKRN--QHELSKQIKACQYKIPQDLSEECLSVITGILQREPEDRPSADELLKSPWL
.|..|.   .  . || |.| ...|.||  .| || . |  .|.  ||.||...|..| ||.
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 84458.m00209.AA AMPK 17-267 36 4.2e-90 267.69 In-house 1-254 (254) Show / Hide 
Range on Protein: 17-267
Range on HMM: 1-254/254
Sequence Identity: 36% (92 aa)

YQLQNAVGRGAFGTVKVAYRPDNGKYYACKIITKHTIDSMIDKSKFEKEIRIMQQLHSPRIVQLFDLL-KDTMNYYIVTELCTGGDMFQQILQNKKIPEE
|...   |.|.|| ||...    |.. | ||. |  | .  .. . ..||.|.. .  | |.||.. . . .   ..|.|  .||. |  | ......|.
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

RAKIYAKQLLEAISYIHKLNVCHRDLKPENILLDNNGDIKLSDFGFSKFI-DG-LTHTSCGSYVYAAPEILEGTDYDPKKSDIWAVGVIIYAMVTGQLPW
 |. . .| . ...|.|.... ||||||||.||| |  ||. ||| |.   || .  |.|||  |||||. .|  |   . |||  ||| |||. | || 
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

TKRNQHELSKQIKACQYKIPQDLSEECLSVITGILQREPEDRPSADELLKSPWL
   |. .| | ||...|.||..||.|. . | ..||  |. | . ... ..||.
DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 84458.m00209.AA Ciliate-E2 17-267 25 1.8e-84 286.93 In-house 1-365 (365) Show / Hide 
Range on Protein: 17-267
Range on HMM: 1-365/365
Sequence Identity: 25% (98 aa)

YQLQNAVGRGAFGTVKVA--YRP---------------------DNGKYYACKIITKHTIDSMIDKSKFEKEIR----------IMQQLHSPRIVQLFDL
| ...  |.|.||.|. .  ..                      ...|.|| ||. |  | ..  . .  .||.          |..|| .| |..... 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

LK--DTMNYYIVTELCTGGDMFQ-----QILQNKKIP------EERAKIYAKQLLE---------------AISYIHKLN-VCHRDLKPENILLDNNGDI
 .  |. |.|.|.|.| |||.|.     .. .|..|.      |. .| . ||.|.               |. |.|. | ..|||.||||||.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLSDFGFSKFIDG----------------------------------LTHTSCGSYVYAAPEILEGTDYDP--------KKSDIWAVGVIIYAMVTGQLP
|..|||.||..|                                   ...| ||.. | |||||.| .||         .|.|||..|||.| |..|..|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

WTKRNQHELSKQIKACQYKIP------------------QDLSEECLSVITG----ILQREPEDRPS-ADELLKSPWL
.         .||| |....|                  ...|.||   |      .||..|| |.. ....|. ||.
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 84458.m00209.AA ULK 17-267 29 5.5e-84 285.32 In-house 1-324 (324) Show / Hide 
Range on Protein: 17-267
Range on HMM: 1-324/324
Sequence Identity: 29% (96 aa)

YQLQNAVGRGAFG-TVKVAYRPDN---GKYYACKIITKHTIDSMIDKS-------KFEKEIRIMQQLH---SPR--IVQLFDLLKDT--MNYYIVTELCT
|.| .  | |.|| .|  ..  ..   ..|.|||.| |  .     ..       ....||.||..|.   .|   ||.|.| ....   |.||..|.| 
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGDMFQQILQNKK---------IPEERAKIYAKQLLEAISYIHKLNVCHRDLKPENILLDNN------------GDIKLSDFGFSKFIDG--LTHTSC--
||| .| | .|||         ..|. |... ||....  ..|| |. |||.||.|||. |.            | .|..||||.|..|   .  . |  
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

--------GSYVYAAPEILE----GTDYDPKKSDIWAVGVIIYAMVTGQLP---WTKRNQH----ELSKQ-------IKACQYKIP-----QDLSEECLS
        |.  | ||.||.    . .|. .|.||| .|.|.| |..|. |   | ...|     .| ..       ||  . ..|     . .|.|| .
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

VITGILQREPEDRPSADELLKSPWL
 | . ||....|| | .|... ||.
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase 84458.m00209.AA ULK 17-267 30 6.2e-83 281.83 In-house 1-329 (329) Show / Hide 
Range on Protein: 17-267
Range on HMM: 1-329/329
Sequence Identity: 30% (99 aa)

YQLQNAVGRGAFGTVKVAYRPDN----GKYYACKIITKHTIDSMIDKSK-------FEKEIRIMQQLHSPR--------IVQLFDLLKDT--MNYYIVTE
|.| .  | |.||.|  ..  ..    ....|||.| | ...   . .        ...||.||..|.||         ||.|.| ....   |.||..|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LCTGGDMFQQILQNKK----------IPEERAKIYAKQLLEAISYIHKLNVCHRDLKPENILLDNN------------GDIKLSDFGFSKFID-G-----
.| ||| .| | .|||          ..|. |... ||.|..  ..|| |. |||.||.|||..|.            | .|..||||.|..| .     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

LTHTSC------GSYVYAAPEILE----GTDYDPKKSDIWAVGVIIYAMVTGQLP---WTKRNQH-----ELSKQ-------IKACQYKIPQD-----LS
...|        |.  | ||.||.    . .|. .|.||| .|.|.| |..|. |   | .. |      .| ..       ||  . ..|.|     .|
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

EECLSVITGILQREPEDRPSADELLKSPWL
.|| . | . ||....|| | .||.. ||.
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 84458.m00209.AA Ciliate-E2-Unclassified 17-267 27 6.8e-78 265.1 In-house 1-352 (352) Show / Hide 
Range on Protein: 17-267
Range on HMM: 1-352/352
Sequence Identity: 27% (97 aa)

YQLQNAVGRGAFGTVKVAYRPDNGKYYACKIITKHTIDSMIDKSKF---------EKEIR-------------IMQQLHSPRIVQLFDLLKDTMNYYIVT
| ..   |.|.||.|. ... ....||| |.. |. |...  . .          ....              |.... .| || .|.  .|. | |||.
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

ELCTGGDMFQQILQNKK-----------------IPEERAK-----IYAKQLLEAISYIHKLN-VCHRDLKPENILLDNNG---DIKLSDFGFSKFIDGL
|.| |||..| | ..||                 ..|. ||      |..|.|....|.|. | ..|||.||||||.||||    ||..|||.||...  
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

------------------THTSCGSYVYA----APEILEGTDYDP---KKSDIWAVGVIIYAMVTGQLPWTKRNQHE----------------LSKQIKA
                  ..| ||.. |     |||.|.|  ||    .|.|||..|||.|.|..|..|   .|. .                | ..||.
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

CQYK--------IPQDLSEECLSVIT----GILQREPEDRPSADELLKSPWL
....        ||...|.|.   |.     .|.  |. |......|. ||.
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 84458.m00209.AA RSK 19-267 31 7.5e-76 258.3 In-house 1-278 (278) Show / Hide 
Range on Protein: 19-267
Range on HMM: 1-278/278
Sequence Identity: 31% (87 aa)

LQNA--VGRGAFGTVKVAYRPDNGKYYACKIITKHTIDSM-IDKSKFEKEIRIMQQLH-SPRIVQLFDLLKDTMNYYIVTELCTGGDMFQQILQNKK---
|. .   | |.. ...   . |.|..|| |.. |..|.    |     .|..|..    .| ||.|..  ..    |...|.| ||..|  ... |    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

IPEERAKIYAKQLLEAISYIHKLNVCHRDLKPENILLDN---NGDIKLSDFGFSKF--ID--GLTHTSCGSYVYAAPEILE----GTDYDPKKSDIWAVG
. |..|..|. ..  |....|.. . ||||||||||.|.   .| |||.||||.|   .|  ..|.| |..  |.|||.|     .  .| |  |.|  |
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHD-KACDWWSLG

VIIYAMVTGQLPWTK---RNQHELSKQIKACQ--YKIP--QDLSEECLSVITGILQREPEDRPS-----ADELLKSPWL
|..| | ||..| .     |..|..|.|. ..   ..|  | ||.|. . |.. |.|.|..|..     |.|....||.
VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 84458.m00209.AA TyrKc 17-265 22 2.1e-17 58.8 SMART 1-280 (280) Show / Hide 
Range on Protein: 17-265
Range on HMM: 1-280/280
Sequence Identity: 22% (66 aa)

YQLQNAVGRGAFGTVKVAYRPDNGKYYACKIITKHTIDSMIDKSKFEKEIRIMQQL--HSPRIVQLFDLLKDT-------MNYYIVTELCTGGDMFQQIL
 .|    |.||||.|  .         | | . ...      .  | .|.||| .|  | | ||.|.    .          ..||.|.. .||  . . 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

QNKK-IPEERAKIYAKQLLEAISYIHKLNVCHRDLKPENILLDNNGDIKLSDFGFSKFIDGL--------THTS----CGS----YVYAAPEILEGTDYD
 ... .. .    .. |  .  .|.|. |. ||||   |.|...|. .| |||| |..|.          . ..    .|     .   ||| .    . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

PKKSDIWAVGVIIYAMVT-GQLPWTK-----RNQHELSKQIKACQYKIPQDL---------SEECLSVITGILQREPEDRPSADELLKSP
. |||.|. || .. . | || |.        .  |. ...|.  .  . .          ..|  ....   ...|||||.  |. .  
T-KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 84458.m00209.AA Pkinase_Tyr 17-165 25 1.8e-08 29.32 Pfam 1-161 (270) Show / Hide 
Range on Protein: 17-165
Range on HMM: 1-161/270
Sequence Identity: 25% (42 aa)

YQLQNAVGRGAFGTVKVAYRP----DNGKYYACKIITKHTIDSMID---KSKFEKEIRIMQQL-HSPRIVQLFDLLK-DTMN--YYIVTELCTGGDMFQQ
 ..    |.||||.|. ..      ...   | |.. |.  ..| .   . .| .|..|| || | | ||.|      .     .|||.|.. .||.   
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE--GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY

ILQ----NKKIPEERAKIYAKQLLEAISYIHKLNVCHRDLKPENILLDNNGDIKLSDFGFSKFI
  .    ..... ..   .. |  .. .| .  |  ||||   |.|...|. .| .||| .. |
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI