84915.m00114

Species: T.vaginalis
Alias: 84915.m00114, TvagK0995
External Links:
Annotation:

Classification

Group: Other
Family: Other-Unique

Sequence

Name Sequence Type Origin Length Description Download
84915.m00114.AA Protein None 427 None Fasta, JSON
84915.m00114.kin_dom Protein Kinase Domain None 289 None Fasta, JSON

Protein domain

Protein domains of 84915.m00114.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 84915.m00114.AA S_TKc 132-420 20 1.1e-45 159.02 SMART 1-231 (231) Show / Hide
Range on Protein: 132-420
Range on HMM: 1-231/231
Sequence Identity: 20% (63 aa)

YQHISDIGSGGYGKISKVLNLIDEQYYALKVVRISKDEISSAVREVQCLAALNSPRIVRYFSSWLESKDNEKEALLYIQMQYVPG--VTLSDYLFQKKD-
|. .  ||.|..||  |. .  . ...|.|...       .. ||.|.|   . | ||... .. .         ||. | |..|   .| ||. ...  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----MDDTERKLILYQITYALSEIHAQNIIHRDFSPNNIIVRDYGKITVIDFGIASIKGKKDYSKQNEHAIASQPRVGSLTLRPIDKLIIKEAGKANRT
     ..  . . ..|||  ||  .| ..|||||  | || . .   | ..|||.| .                                          
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----------------------------------------

VKEVGTPLYSSPRQLSGHHSGPSDDVYSLGIIAFEIYSRFTTWMEKTLSIRNLRSSRKIPPEFSAKYPEISSLVESCIFTESKQRPTVLDILN-------
   .||| | .|  |  ...... |..|.|.| .| ... . .      . ..              ||  .... |   . ..|||. ..|.       
TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKC

LPLF
 | |
HPWF

Kinase 84915.m00114.AA STE 132-420 16 9.5e-30 102.27 In-house 1-359 (359) Show / Hide
Range on Protein: 132-420
Range on HMM: 1-359/359
Sequence Identity: 16% (66 aa)

YQHISDIGSGGYGKISKVLNLI---------------DEQYYALKVVRISK------------------DEISSAVREVQCLAALN--SPRIVRYFSSWL
...|. ||.|..|.  | .|                   ...| |......                  .|. .  .|.. .  .|  .| ||.|. . .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

ESKDNEKE-ALLYIQMQYVPGVTLSDYLFQK----KDMD----------DTERKLILYQITYA-LSEIHAQNIIHRDFSPNNIIVRDYGKITVIDFGIAS
   .|.|.   |.| | |..| .|.| . .|    |...           .. . |..||  . |. .| ..|||||  | || .     .  .|||...
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

IKGK---KDYSKQNEHAIASQPRVGSLTLRPIDKLIIKEAGKAN----------RTVKEVGTPLYSSPRQLSG------HHSGPSDDVYSLGIIAFEIYS
.  .   .. .                               .|          ..   |||| . .|  ...      .. . . |..|||. . |   
QLTDSMANI-Q-S-----------------------------NNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMAT

RFTTWME-KTL----SIRNL--------------RSSRKIPPEFS----------------AKYPEISSLVESCIFTESKQRPTVLDILN--LPLF
    |.. . .     | .                 . ..|...|                   ||    .. |   . ..|||. . |.   | .
GKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI

Kinase 84915.m00114.AA Ciliate-E2 132-420 20 1.8e-28 94.85 In-house 1-365 (365) Show / Hide
Range on Protein: 132-420
Range on HMM: 1-365/365
Sequence Identity: 20% (81 aa)

YQHISDIGSGGYG-----KISKV-----LNLIDEQY--------------YALKVVR----ISKDEISSAVREVQ----------CLAALNSPRIVRYFS
|  |  ||.|..|     |  ||     ...|| |.              ||.|...    ...  . .  ||..           |  ||.| |.... 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

SWLE-SKDNEKEALLYIQMQYVPGVTLSDYLFQK-----------KDMDDTERKLILYQITY---------------ALSEIHAQN-IIHRDFSPNNIIV
.. | ...|     .|. | |. | .| ||. ..           | ... |.| | .||..               || ..| .| |||||  |.||..
CFQEKDDNN-----IYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF

RDYGKITVIDFGIA-------------SIKGKKDYSKQNEHAIASQPRVGSLTLRPIDKLIIKEAGKANRTVKEVGTPLYSSPRQLS---------GHHS
     | .||||..             .. ... . |....   .  .           .||..    | .   .||| | .|  |.         ... 
-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMD-----------QIIQQ----NMFNTICGTPGYMAPEILNGKKYDNQQKQKGY

GPSDDVYSLGIIAFEIYSRFTTWMEKTLSIRNLRSSRK----IPPEF-------------SAKYPEIS--SLVES----CIFTESKQRPT-VLDILNLPL
. . |..|||.| .|  .  . .         ..   .    .|...             | |. . .   |       ..  . ..|.|   .||| | 
DYKCDIWSLGVILYEMLFGKPPF---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPW

F
|
F

Kinase 84915.m00114.AA Pkinase 132-279 27 4.5e-26 93.27 Pfam 1-159 (293) Show / Hide
Range on Protein: 132-279
Range on HMM: 1-159/293
Sequence Identity: 27% (46 aa)

YQHISDIGSGGYGKISKVLNLIDEQYYALKVVRISKDEISS---AVR--EVQCLAALNSPRIVRYFSSWLESKDNEKEALLYIQMQYVPGV----TLSDY
|. .. ||||..|.  |  .  ... .|.|... .... .    ..|  |.| .. ||.| |||.. .. .      .  .|. | |..|      |.||
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED------KDHIYMVMEYCEGGLYVMDLFDY

LF--QKKDM--DDTERKLILYQITYALSEIHAQNIIHRDFSPNNIIVRDYGKI----TVIDFGIA
.   ... .  .. | | ..|||  .|  .|...|||||  | || . . | |     ..|||.|
ISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLA

Kinase 84915.m00114.AA Ciliate-E2-Unclassified 132-359 21 1.2e-23 78.97 In-house 1-263 (352) Show / Hide
Range on Protein: 132-359
Range on HMM: 1-263/352
Sequence Identity: 21% (63 aa)

YQHISDIGSGGYGKISKVLNLIDEQY-----------YALKVVRISKDEISSAVREVQCL----------------AALNSPRIVRYFSSWLESKDNEKE
|  |  ||.||.||. |. .  . ||           |. | .. .. ||.    |....                  ...| ||..|         ...
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYC------FQDK

ALLYIQMQYVPGVTLSDYL-----------------FQKKDMDDTERK-----LILYQITYALSEIHAQN-IIHRDFSPNNIIVRDYG---KITVIDFGI
  .|| |.|..| .|..|.                  |.|  .. . |      ...||  .|. .| .| |||||  |.||.. . |   .| .|||||
QNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGI

ASIKGKKDYSKQNEHAIASQPRVGSLTLRPIDKLIIKEAGKANRTVKE--------VGTPLYS----SPRQLSG-HHSGPSD---DVYSLGIIAFEI
..  .. .... ..                          . ...           .||| |     .|  | | ......    |..|||.|..|.
SKKYQQNNNCD-TNQ-------------------------Q-QKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEM

Kinase 84915.m00114.AA Ciliate-A1 132-281 25 5.5e-23 75.06 In-house 1-150 (301) Show / Hide
Range on Protein: 132-281
Range on HMM: 1-150/301
Sequence Identity: 25% (38 aa)

YQHISDIGSGGYGKISKVLNLIDEQ-YYALKVVRISKDEI-SSAVREVQCLAALNSPRIVRYFSSWLESKDNEKEALLYIQMQYVPGVTLSDYLFQKKDM
|     |..|..| . .. ..  .. | ..|.. ..  |.  ... | . .  .|..  .  .   |. ..| ||   .| | |  .  |..|  |.. |
YHVVQLIDKGSFGVVMRAYDIQNQKKYLCCKIIICTNFEQYKNNIQEYRKCKQINHNNVIKNYQQ-LYYNTNNKE-CMFIIMEYCQYGNLFNYCYQNDYM

DDTERKLILYQITYALSEIHAQNIIHRDFSPNNIIVRDYGKITVIDFGIASI
   |   |.|||.  .. || .||.|||  | ||.. .  |. ..|.|.  .
KKEEIYEICYQIIEGYADIHDHNILHRDLKPQNILIHFDDKWKICDLGMSKQ

Kinase 84915.m00114.AA NEK 132-279 28 1.1e-22 77.0 In-house 1-170 (286) Show / Hide
Range on Protein: 132-279
Range on HMM: 1-170/286
Sequence Identity: 28% (49 aa)

YQHISDIGSGGYGKISKVLNLIDEQY-----YALKVVRISK---DEISSAV-REVQCLAALNSPRIVRYFSSWLESKDNEKEALLYIQMQYVP-GVTLSD
|..|  ||.| .||  ||   .|..      |..| . ...    |   |.  ||. |. |..| ||.|. |..| ..|     |.| | |   | .|..
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNN----CLCIVMEYCEGGGDLYQ

Y---LFQKK-DMDDTERKLIL---YQITYALSEIHAQ-----NIIHRDFSPNNIIVRDYGK----ITVIDFGIA
    . ..|   .  | . |.   .|.  || ..| .     .|.|||  |.||   . ..    . . ||||.
KIKSIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGIS

Kinase 84915.m00114.AA PEK 327-420 37 1.2e-22 75.09 In-house 550-655 (655) Show / Hide
Range on Protein: 327-420
Range on HMM: 550-655/655
Sequence Identity: 37% (40 aa)

VGTPLYSSPRQLSGHHSGPSD-----DVYSLGIIAFEIYSRFTTWM-EKTLSIRNLRS-SRKIPPEFS-----AKYPEISSLVESCIFTESKQRPTVLDI
|||.||.|| |||| |.. |      |.|||||| || . .| | | |..  ...||. | ..| .|.      |||. ....  ..    .|||.. .|
VGTCLYMSPEQLSGQHYQKSHYNHKVDMYSLGIIFFEMWYPFFTTMMERVKTLTDLRDESIQFPGDFPPKWFDNKYPKQADFIQWMLSHDPQQRPSAQQI

LNLPLF
|. ..|
LQHEFF

Kinase 84915.m00114.AA PEK 325-420 28 3.3e-17 52.86 In-house 647-758 (758) Show / Hide
Range on Protein: 325-420
Range on HMM: 647-758/758
Sequence Identity: 28% (32 aa)

KEVGTPLYSSPRQLSGH----HSGPSD------------DVYSLGIIAFEIYSR-FTTWMEKTLSIRNLRSSRKIPPEFSAKYPEISSLVESCIFTESKQ
. |||.|| || |...       . .             | ||||.|.|| .   | | ||..  ...|| . ..|. |  |||. . ..   . ..  .
VQVGTHLYMSPEQCHHQSVFGTGTYTNPEQKKTWYNHKVDIYSLGLIFFELIHPGFSTQMERIRTMCDLR-NGQWPKWFTQKYPQEYEFIQQMMSMNPDE

RPTVLDILNLPLF
|||  .|.  ..|
RPTADQISMHDFF

Kinase 84915.m00114.AA PEK 132-201 30 4.4e-17 55.37 In-house 1-89 (655) Show / Hide
Range on Protein: 132-201
Range on HMM: 1-89/655
Sequence Identity: 30% (27 aa)

YQHISDIGSGGY-GKISKVLNLIDEQYYALKVVRISKDE------------------ISSAVREVQCLAALNSPRIVRYFSSWLESKDN
...|. .|.||. |   || | .|..|||.| ... . .                  . .. |||. || || | ||||...|.|. ..
FEEIQCLGKGGFGGQVYKVQNKLDGCYYAIKRIKLNWKQRKQPCITQECMIHKCKKHCEKVLREVKTLARLNHPNIVRYHNAWIEKPEE

Kinase 84915.m00114.AA GCN2 327-420 30 2.4e-15 49.8 In-house 414-511 (511) Show / Hide
Range on Protein: 327-420
Range on HMM: 414-511/511
Sequence Identity: 30% (30 aa)

VGTPLYSSPRQLSGHHSGPSDDVYSL-GIIAFEIYSR-FTTWMEKTLSIRNLRSSRKIPPEFSA----KYPEISSLVESCIFTESKQRPTVLDILNLPLF
||||.| .| |...|. .   |.||| ||| ||.  . | | ||.   ...|| | ..|. | .    ..... .....|.   ...||.. ..|. .. 
VGTPFYMCPEQQKSHY-NQKVDMYSLGGIIFFEMWYPPFCTQMERVQILKQLR-SCEFPQDFDKKVDNHHKDQQDMIRWCLNHDPQKRPSAQQLLQHEFL





Kinase 84915.m00114.AA PEK 132-197 35 2.9e-15 46.26 In-house 1-76 (758) Show / Hide
Range on Protein: 132-197
Range on HMM: 1-76/758
Sequence Identity: 35% (27 aa)

YQHISDIGSGGYGKISKVLNLIDEQYYALKVVRISK------DEISSAV----REVQCLAALNSPRIVRYFSSWLE
. ||. .|.||.|   .. |  |. .||.| .. .          .||     |||  || |. . |||||..|||
FEHIQCLGHGGFGVVFRAKNKVDMNNYAIKRITFPNSNNQSPTNRESAREKVMREVRTLAMLDHHNIVRYFNAWLE

Kinase 84915.m00114.AA HRI 132-197 39 4.4e-15 48.92 In-house 1-69 (613) Show / Hide
Range on Protein: 132-197
Range on HMM: 1-69/613
Sequence Identity: 39% (27 aa)

YQHISDIGSGGYGKISKVLNLIDEQYYALKVVRISKD---EISSAVREVQCLAALNSPRIVRYFSSWLE
.     || ||||.. || .  | |.|| | ..| |    .. .  |||  || |. . ||||  .|.|
FEQKEIIGKGGYGRVYKVRHKLDKQHYAIKKIKIKKRTKCSCMKMQREVKVLACLQHHNIVRYHQAWIE

Kinase 84915.m00114.AA PEK-Unclassified 132-197 25 9.3e-12 36.37 In-house 1-74 (835) Show / Hide
Range on Protein: 132-197
Range on HMM: 1-74/835
Sequence Identity: 25% (19 aa)

YQHISDIGSGGYGKISKVLNLIDEQYYALKVVRIS--------KDEISSAVREVQCLAALNSPRIVRYFSSWLE
.  .  || ||.. . .. . .|.  || | ...                ..||  .| .| | |.||. || |
FNQVQKIGQGGFAIVYQCCHKFDQMEYAVKQIHVNIKDIKEDLQKHYEKEIMEVRYMAQVNHPNIIRYYHSWIE

Kinase 84915.m00114.AA GCN2 132-202 32 1.1e-11 36.79 In-house 1-77 (511) Show / Hide
Range on Protein: 132-202
Range on HMM: 1-77/511
Sequence Identity: 32% (25 aa)

YQHISDIGSGGYGKISK-VLNLIDEQYYALKVVRI--SKDEISS---AVREVQCLAALNSPRIVRYFSSWLESKDNE
 . |  .| || |...| | |  |..|||.|  .|  ......      |||  |. |. . .|||. .|.|. | .
FEEICCLGKGGFGQVVKNVRNMHDGRYYAIKKWPINWKQRKLPCKHKIMREVKLLCRLHHQHVVRYYQAWIEKCDEP

Kinase 84915.m00114.AA HRI 327-420 31 4.6e-11 34.42 In-house 521-613 (613) Show / Hide
Range on Protein: 327-420
Range on HMM: 521-613/613
Sequence Identity: 31% (30 aa)

VGTPLYSSPRQLSGHHSGPSDDVYSLGIIAFEIYSRFTTWMEKTLSIRNLRSSRKIPPEFSAKYPEISSLVESCIFTESKQRPTVLDILNLPLF
||| .| || || |       | ||.|.| || .  | | ||.   .  .|  . ||   . . |     .       . |||  . .|   ||
VGTCTYASPEQLDGSQYDNKSDMYSMGVILFELFQPFGTEMERAEVLTGVRTGQ-IPESLRKRCPVQAKYIQHLTRRNASQRPSAIQLLQSELF

Kinase 84915.m00114.AA Pkinase 327-420 19 6.8e-11 39.61 Pfam 172-293 (293) Show / Hide
Range on Protein: 327-420
Range on HMM: 172-293/293
Sequence Identity: 19% (24 aa)

VGTPLYSSPRQLS-GHHSGPSDDVYSLGIIAFEIYSRFTTWMEK------TLSIRNLRSSRKIPPEFSAKY---------------------PEISSLVE
.||| | .|  .  | . ||. |..|.|.| .| ... . . ..      .   .  |  ...... . .                      .|  ....
CGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIK

SCIFTESKQRPTVLDILNLPLF
.|.    |.|||  .||. | |
WCLCKDPKKRPTAEQILQHPWF

Kinase 84915.m00114.AA GCN2 206-280 40 8.7e-11 33.58 In-house 281-356 (511) Show / Hide
Range on Protein: 206-280
Range on HMM: 281-356/511
Sequence Identity: 40% (31 aa)

LLYIQMQYVPGVTLSDYLFQK-KDMDDTERKLILYQITYALSEIHAQNIIHRDFSPNNIIVRDYGKITVIDFGIAS
.||||| |..| ||..|. .    ||..| . .. ||  .|. || |..|||| .| || .   | . . |||.|.
YLYIQMEYCEGKTLRQYIDNHGWCMDHDELWRYFRQILEGLNYIHSQGMIHRDLKPSNIFLDCCGNVKIGDFGLAT

Kinase 84915.m00114.AA PEK 202-279 22 1.2e-10 32.5 In-house 353-479 (655) Show / Hide
Range on Protein: 202-279
Range on HMM: 353-479/655
Sequence Identity: 22% (29 aa)

EKEALLYIQMQYVPGVTLSDYLFQKK--------------------------------------------DMDDTERKLILYQITYALSEIHAQNIIHRD
.....|||||.|... ||.|.. . .                                              | .. . |. ||  .|  || | .||||
YQCHYLYIQMEYCEKKTLRDWIDNNGCPVQFNYWRRNSCKNHYNNYIMNQCCFQSTWSMNMRQWDENNCMFWDKDQCWRIFRQILEGLNYIHSQGMIHRD

FSPNNIIVRDYGK-----ITVIDFGIA
  | || . . |.     . . |||.|
LKPSNIFLDCDGQHHQMQVKIGDFGLA

Kinase 84915.m00114.AA PEK-Unclassified 327-419 25 9.7e-10 29.13 In-house 734-835 (835) Show / Hide
Range on Protein: 327-419
Range on HMM: 734-835/835
Sequence Identity: 25% (27 aa)

VGTPLYSSPRQL-----------SGHHSGPSDDVYSLGIIAFEIYSRFTTWMEKTLSIRNLRSSRKIPPEFSAKYPEISSLVESCIFTESKQRPTVLDIL
.|| .|||. |.            .       |.||.||| |.. . . | ||.   | |..    .|  | ||.| .  ..   .  . ..|| .|  .
CGTYTYSSNEQESQKKVRIKAHFQADFYNHRTDIYSVGIIFFQMFHQMNTTMERVKTIQNCKKG-ELPKHFCAKFPRLAEIIKDSLSNDPQKRP-LLSKI

NLPL
   |
EQTL

Kinase 84915.m00114.AA PEK 207-263 35 6.4e-09 24.66 In-house 414-473 (758) Show / Hide
Range on Protein: 207-263
Range on HMM: 414-473/758
Sequence Identity: 35% (21 aa)

LYIQMQYVPGVTLSDYLFQKKDMDDTERKLIL---YQITYALSEIHAQNIIHRDFSPNNI
.|||||.  . ||.| .   ..|..... ..|    ||  ..  ||   .||||. | ||
MYIQMQLCRKETLKDWMRNRCTMESRPWMHMLHWFHQICEGVNYIHSKGMIHRDLKPSNI

Kinase 84915.m00114.AA TyrKc 132-420 17 1.4e-07 -100.07 SMART 1-280 (280) Show / Hide
Range on Protein: 132-420
Range on HMM: 1-280/280
Sequence Identity: 17% (55 aa)

YQHISDIGSGGYGKISKVLNLIDEQYYALKVVRISKDEISSAVREVQCLAAL--NSPRIVRYFSSWLESKDNEKE---ALLYIQMQYVPGVTLSDYLFQK
 . .  .|.| .|.. |       .  | |... ..  .    || . .  |  . | ||| .   .... |        |.| | |.|.  | |||  .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN--FMYIEPLMIVMEYMPHGDLKDYLRKH

KD-MDDTERKLILYQITYALSEIHAQNIIHRDFSPNNIIVRDYGKITVIDFGIASIKGKKDYSKQNEHAIASQPRVGSLTLRPIDKLIIKEAG--KAN--
..     .   . .||    . .| .|.||||    |. | . . . . ||| .   . .| .                      |  .. ..   ..  
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG-------------------ESKDYYRKKEHKGGKTM

RTVKEVGTPLYSSPRQLSGHHSGPSDDVYSLGIIAFEIYSR---FTTW-----MEKTLSIRNLRSSRKIPPEFSA-------KYPEISSLVESCIFTESK
  ..        .|  .  .   .  ||.| |.  .||...            |. .  |..... .  |.  ..         .|. .. ..|   . .
LPIR------WMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPE

QRPTVLDILNLPLF
.|||  .|    .|
DRPTFSEI--HECF

Kinase 84915.m00114.AA NEK 391-420 23 1.8e-05 15.71 In-house 257-286 (286) Show / Hide
Range on Protein: 391-420
Range on HMM: 257-286/286
Sequence Identity: 23% (7 aa)

PEISSLVESCIFTESKQRPTVLDILNLPLF
.. ..|.....  . .|||.. .||..|. 
QDLQNLISQMLQKDPEQRPSCNQILEMPFI

Kinase 84915.m00114.AA PEK-Unclassified 237-279 42 4.1e-05 12.52 In-house 618-662 (835) Show / Hide
Range on Protein: 237-279
Range on HMM: 618-662/835
Sequence Identity: 42% (19 aa)

ILYQITYALSEIHAQN-IIHRDFSPNNIIVRDY-GKITVIDFGIA
|. ||  ||  || |  ..|||  | || | .    | . ||| .
ITRQIIKALYHIHHQCKMVHRDIKPHNIFVCQNPMQIKIGDFGLV

Kinase 84915.m00114.AA APH 253-281 33 0.000606 14.33 Pfam 172-204 (248) Show / Hide
Range on Protein: 253-281
Range on HMM: 172-204/248
Sequence Identity: 33% (11 aa)

IIHRDFSPNNIIVR---DYGKI-TVIDFGIASI
..|.|| |.|....   | |..  |||.. | .
WCHGDFHPGNVMWDPRPDGGRVTGVIDWDDACW

Kinase 84915.m00114.AA Ciliate-E2-Unclassified 391-420 26 0.013605 4.84 In-house 319-352 (352) Show / Hide
Range on Protein: 391-420
Range on HMM: 319-352/352
Sequence Identity: 26% (9 aa)

PEISSLVE----SCIFTESKQRPTVLDILNLPLF
||   ...    ...    ..|.|  .||| |.|
PEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase 84915.m00114.AA HRI 248-279 38 0.050179 1.85 In-house 449-484 (613) Show / Hide
Range on Protein: 248-279
Range on HMM: 449-484/613
Sequence Identity: 38% (14 aa)

IHAQNIIHRDFSPNNIIVRDYGK----ITVIDFGIA
||   |.|||  | ||   |       . . ||| |
IHNMFIVHRDVKPRNIFLHDPDQGHPQVKIGDFGLA