Gene 83714.m00243 (T.vaginalis)
83714.m00243
Species: T.vaginalis
Alias: TvagK0758, 83714.m00243
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| 83714.m00243.AA | Protein | None | 346 | None | Fasta, JSON |
| 83714.m00243.kin_dom | Protein Kinase Domain | None | 284 | None | Fasta, JSON |
Protein domains of 83714.m00243.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 83714.m00243.AA | GSK | 40-323 | 39 | 1.7e-128 | 394.76 | In-house | 1-328 (328) | Show / Hide |
Range on Protein: 40-323 Range on HMM: 1-328/328 Sequence Identity: 39% (130 aa) YNPLNIIGKGAFGVVFCARAP-----TGDV----VAIKKVLIDPRYK-NRELDIISTI---KHHNCITLRDSFRIQGRKKGE--IFLN-IVMDYYPMTLY | . || |.||||..| . |... ||||||. |.||| ||||.|. . .| |...|. .| .. || | ..| .||.| |.||| YEEMKVIGHGSFGVVYQAYMNSPSNETKEIWLGPVAIKKVWQDKRYKCNRELQIMKMLGKLDHPNIVRLKYFFYMHYEKKDENHVYCNCLVMEYMPQTLY DFTLNYRNQRLYVPILYIKLFSYQLFAGLRYLHKRRIVHRDIKPQNLLVNQETGVLKICDFGSAKIIKP--GDKSVSYIASRFYRAPELILDCQVYGPPI .. |.... .||..|||..||.| ||.|||. |.||||||||.||...|||||||||||||...| . ...||| ||.|||||||..|. |. | QVIRHYVKNKQQMPIIHIKLYMYQMFRGLAYLHSHGICHRDIKPQNILVDPDTGVLKICDFGSAKQLEPNKNEPNISYICSRYYRAPELIFGCTNYTCQI DIWASGCVIAEAINSASPLFVSETSNGQINAIIKIFGQPNPEDFADYAHGNSVPTDVQQ--------ETTLEK-------------------VLPG-HTP |.| |||.|| . ||| ..|. |. |||..| |. |.. .| | .. . . | .. ||. DVWSCGCVMAEML-KGQPLFPGDSSVDQLVEIIKMLGTPTKEQIQSM--NPSYPEFKFPYWSFQQIKPHPWQKNDTKYEYQTYYHKKYRTVYMFKWCHTD PD-LIDLLKKCFIYNPNERITAEQAMAHPCF .. .|||..||..|.|..|... .|.||| | MQDWIDLISKCLVYDPKKRLSPLEACAHPFF |
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| Kinase | 83714.m00243.AA | CMGC | 40-323 | 20 | 2.4e-103 | 340.55 | In-house | 1-513 (513) | Show / Hide |
Range on Protein: 40-323
Range on HMM: 1-513/513
Sequence Identity: 20% (105 aa)
YNPLNIIGKGAFGVVFCARA---------------PTGDVVAIKKVLIDPRYKN----------------RELDIISTIK----------------HHN-
| .. ||.|..|||. .| |. .|||||. .. |.. ||. | .. |||
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN
CITLRDSFRIQG-RKKGEI----------FLNIVMDYYPMTLYDFTLNYR------------------------NQRLYVPILYIKLFSYQLFAGLR--Y
...|.|.|. . ..... |..|..| ...||.. |.. .. | .| .|. ..||.. || |
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLKY
LHKRR--IVHRDIKPQNLLVNQET-------------------GVLKICDFGSAKIIKPGDK----------------------SVSYIASRFYRAPELI
.|... |.|||.||.|.|.|... |.|||||||.|... | .. .|...|.|||||..
CHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEIL
LDC---------QVYGPPIDIWASGCVIAEAINS-------ASPLFVSETS-----------NGQINAIIKIFGQPN---------------PEDFADYA
| . . |..|||.|. ||..|| .. ||| ... |.. |.|..| |. .|.. ..
LGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMI
HGNSVPT----------------------------DVQQETTLEKVLPGHTP----------------------------------PDLIDLLKKCFIYN
.. .. ..... |.| . |..||||||...|.
KLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYD
PNERITAEQAMAHPCF
|..|||||||..|| |
PDKRITAEQALQHPYF
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| Kinase | 83714.m00243.AA | S_TKc | 40-323 | 26 | 2.1e-79 | 270.99 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 40-323 Range on HMM: 1-231/231 Sequence Identity: 26% (80 aa) YNPLNIIGKGAFGVVFCARAPT-GDVVAIKKVLIDPRYKNRELDIISTIKHHNCITLRDSFRIQGRKKGEIFLNIVMDYYPM---TLYDFTLNYRNQRLY | |..|||||||.|...| | .||||.. . ||..| . .| | ..| |.|. .| .||.| . .|.|. ... ..|. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---EHIRREIQILKK-HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR --VPILYIKLFSYQLFAGLRYLHKRRIVHRDIKPQNLLVNQETGVLKICDFGSAKIIKPGDKSVSYIASRFYRAPELILDCQVYGP-PIDIWASGCVIAE | .. . ||.. .| |.|...|.|||.||.|.|... ..||||||.|... ... ...|.|||.. ||. ..|.|. ||...| FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYE AINSASPLFVSETSNGQINAIIKIFGQPNPEDFADYAHGNSVPTDVQQETTLEKVLPGHTPPDLIDLLKKCFIYNPNERITAEQAMA-------HPCF . |.| |.....|. | .|...|...||. ..|..|.|| .|.. || | MLC-GYPPFP------QMQMMFKKIG----------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | 83714.m00243.AA | CDK | 40-323 | 28 | 3.8e-72 | 230.08 | In-house | 1-284 (284) | Show / Hide |
Range on Protein: 40-323 Range on HMM: 1-284/284 Sequence Identity: 28% (93 aa) YNPLNIIGKGAFGVVFCARAPT-G-----DVVAIKKVLIDP--------RYKN---RELDIISTIKHHNCITLRDSFRIQ----GRKKG--EIFLNIVMD | |. || |..|||. || | ..||.||. .. || . . |.| ..|.| . . |. | | .|.. YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNN-KDKHENKLYMVFE YYPMTLYDFTLNYRNQRLYVPILYIKLFSYQLFAGLRYLHKRRIVHRDIKPQNLLVNQETGV-----LKICDFGSAKIIK-------PGDKSVSYIASRF | .. |. . || . .|| || |.|...|.|||.||||.|.| ..|. ||| ||| |.. | . . . . YMDHDLKKYMD-------------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILIN-NNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLW YRAPELILDCQVYG--PPIDIWASGCVIAEAIN--SASPLFVSETSNGQINAIIKIFGQPNPEDFADYAHGNSVPTDVQQETTLEKVLPGHTPPDLIDLL |||||| | .. |. .|||.|. ||..|| .. . ||| .. |. |..|.| |.... . . ||| YRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY-----------------------DLL KKCFIYNPNERITAEQAMAHPCF |.. |.|. ||.||||. || | NKMLCYDPKKRISAEQALQHPYF |
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| Kinase | 83714.m00243.AA | Pkinase | 40-323 | 27 | 5.3e-67 | 233.7 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 40-323
Range on HMM: 1-293/293
Sequence Identity: 27% (85 aa)
YNPLNIIGKGAFGVVF-CARAPTGDVVAIKKVLIDPRYKNR--------ELDIISTIKHHNCITLRDSFRIQGRKKGEIFLNIVMDYYPMTLYDFTLNY-
| . .||.|.||.|. | . ||..||.|.. . . .. |. | ..| | ..|.|.|. |..| .||.| ...|| .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED----KDHIY--MVMEYCEGGLY-VMDLFD
-----RNQRLYVPILYIKLFSYQLFAGLRYLHKRRIVHRDIKPQNLLVNQETGVL----KICDFGSAKI--IKPGDKSVSYIASRFYRAPELILDCQVYG
|. ..| . .| . ||.. || |.|...|.|||.||.|.|.. ..|.. ||||||.|| . .. .. ...|.|||.|...| ||
YISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYG
PPIDIWASGCVIAEAINSASPLFVSE-TSNGQINAIIKIFGQPNPEDFADYAHGNSVP----TDVQQETTLEKVLPGHTPPDLIDLLKKCFIYNPNERIT
|..|.|. ||...| .. |.| .. .. . .. . .|. |. |. .|.. .. . . . .... ......|..|.|. ..|..|.|
PKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRH-W-H-F-HWTF-HNWSEECKDFIKWCLCKDPKKRPT
AEQAMAHPCF
|||.. || |
AEQILQHPWF
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| Kinase | 83714.m00243.AA | RCK | 111-323 | 34 | 1.6e-48 | 151.95 | In-house | 75-298 (298) | Show / Hide |
Range on Protein: 111-323 Range on HMM: 75-298/298 Sequence Identity: 34% (79 aa) LNIVMDYYPMTLYDFTLNYRNQRLYVPILY--IKLFSYQLFAGLRYLHKRRIVHRDIKPQNLLVNQE--------TGVLKICDFGSAKIIKPGDKS--VS | .|. | | || .. .. | |.| || ||...|| ..|| . |||.|| |.... . ....||.|||... | .| LYFVFEYMDMNLYQMMKDFKERRKYLPENQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIR--SKPPYTD YIASRFYRAPELILDCQVYGPPIDIWASGCVIAEAINSASPLF--VSETSNGQINAIIKIFGQPNPEDFADYA-HGNSVPTDVQQ--ETTLEKVLPGHTP |. .| |||||..| |. | |.|||| ||...| . . ||| || ||. |.|. | ||..| | . ... . .| . |....| . YVSTRWYRAPECLLRCTYYNSPMDIWAVGCIMYE-LYMLRPLFPGSSEID--QIFKICKVMGTPNKKDWPDGYKLASQMNFNFPQCKGMPLKQLIPN-CS PDLIDLLKKCFIYNPNERITAEQAMAHPCF .|.|.|..|. ..|..||||.|| || | QDCIELMEKMLQWDPQKRITAQQALQHPYF |
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| Kinase | 83714.m00243.AA | MAPK | 141-323 | 33 | 1.9e-45 | 155.01 | In-house | 117-328 (328) | Show / Hide |
Range on Protein: 141-323 Range on HMM: 117-328/328 Sequence Identity: 33% (72 aa) IKLFSYQLFAG--LRYLHKRRIVHRDIKPQNLLVNQETGVLKICDFGSAKIIKPGDKSV---------------SYIASRFYRAPELILD--CQVYGPPI |. | ||. | | |.| ...|||.|| |.|||.. . ||||||| | .| | .. |.| |.|||||..| . | . IQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNEN-CDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAPEIMLNWIWMHYTKAV DIWASGCVIAEAINSASPLFVSETSNGQINAIIKIFGQPNPEDFADYAH-----GNSVPT----DVQQETTLEKVLPG---HTPPDLIDLLKKCFIYNPN |.|. || || .. ||| . . |.| |... | | .|.| . | . .. ..||..|. .. |. ||||.| .|. DMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTP-SEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANPQAIDLLEKMLVFDPD ERITAEQAMAHPCF .|||.|.|..|| | KRITVEEALQHPYF |
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| Kinase | 83714.m00243.AA | CDC2 | 40-257 | 30 | 3.1e-43 | 130.4 | In-house | 1-222 (301) | Show / Hide |
Range on Protein: 40-257 Range on HMM: 1-222/301 Sequence Identity: 30% (71 aa) YNPLNIIGKGAFGVVFCAR-APTGDVVAIKKVLIDPRYKN--------RELDIISTIK-HHNCITLRDSFRIQGRKKGEIFLNIVMDYYPMTLYDFTLNY | .. ||.| .|||. .. |...||.||. .. ||. .. .| | | ..|.| . . | .| .|. | | .. .. YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-------NKLYMVFEYLDMDLKKYMDMS RNQRLYVPILYIKLFSYQLFAGLRYLHKRRIVHRDIKPQNLLVNQETGVLKICDFGSAKIIK-PGDKSV--SYIASRFYRAPELILDCQVYGPPIDIWAS .. ..| ..| . ||. |. ..| |||.|||.||||.|.. ..|..|| ||| |. . | .. . . |||||. | |. | |.|.|. IPKNKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILID-KKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSI GCVIAEA-IN-SASPLFVSETSNGQINAIIKIF ||..|| .. . ||| . .| . ||| GCIFAEMFMDVTKKPLFHGDS---EIDQLFKIF |
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| Kinase | 83714.m00243.AA | CAMK | 45-229 | 16 | 2e-40 | 127.51 | In-house | 1-323 (425) | Show / Hide |
Range on Protein: 45-229
Range on HMM: 1-323/425
Sequence Identity: 16% (54 aa)
IIGKGAFGVVFCARAP-TG------------DVVAIKKVLID-----------------------------PRYKN---RELDIIST-------IKHHNC
..|.|.||.|. .. |. |||| . . |. . ||..| .. ..| |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
ITLRDSFR---------IQG-RKKG-----EIFLNIVM---DYYPMT-----LYDFTLNYRNQR-----------LYVPILYIKLFSYQLFAGLRYLHKR
| | . . . . . . .. .|| .| . |.|. .. . ... . . |. ...|.|..
IKLYEVYEDPHYFKNTND-YET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSH
RIVHRDIKPQNLLVNQET----------------GVLKICDFGSAKIIKP------------------------GDKSVSYIASRFYRA-PELILD----
|||||.|| |.|... . .||.||| |....| |.| . . | | ||...
NIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC
---------CQVYGPPIDIWASGCV
. |||..|.|. |..
NMQNATDEEKPYYGPKCDMWSCGVI
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| Kinase | 83714.m00243.AA | ERK | 141-323 | 36 | 4.3e-39 | 136.21 | In-house | 110-307 (307) | Show / Hide |
Range on Protein: 141-323 Range on HMM: 110-307/307 Sequence Identity: 36% (72 aa) IKLFSYQLFAGLRYLHKRRIVHRDIKPQNLLVNQETGVLKICDFGSAKIIKPGDKSV---------SYIASRFYRAPELILDCQVYGPPIDIWASGCVIA .. | ||. || |.| ..|||.|| |.||| ..||||||| | .. .. . |.|.| |||||..| | | ..|||. || .| CQYFMYQILCGLKYIHSANVIHRDLKPSNILVNSN-CDLKICDFGLARCFDASYQENHECNQNFMTEYVATRWYRAPEIMLSWQKYTKAMDIWSCGCIFA EAINSASPLFVSETSNGQINAIIKIFGQP-NPEDFADY------AHGNSVPTDVQQETTLEKVLPGHT-PPDLIDLLKKCFIYNPNERITAEQAMAHPCF | .. ||| . . .|||.|..| | | ||. . . | |.. .|.. | . |. ||||.| .|..|||.|.. .|| | EMLG-RKPLFPGKDYVHQINRIFQIIGTPHSEEDLQYICSENAWKYIKNLPNPVRPPKPWENIFPNANCNPQAIDLLEKMLVFDPDKRITVEECLEHPYF |
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| Kinase | 83714.m00243.AA | CDKL | 146-232 | 46 | 2.8e-37 | 124.99 | In-house | 105-192 (286) | Show / Hide |
Range on Protein: 146-232 Range on HMM: 105-192/286 Sequence Identity: 46% (41 aa) YQLFAGLRYLHKRRIVHRDIKPQNLLVNQETGVLKICDFGSAKIIK-PGDKSVSYIASRFYRAPELILDCQVYGPPIDIWASGCVIAE .|. .. ..|| ..|||||| |.|.. |..|.|||| |.... ||. | | | |||||| .. ||.|.|||| |||.|| WQILKAINFCHKHNCIHRDIKPENILITPKNGQVKLCDFGFARMLAKPGEIYTDYVATRWYRAPELLVGDTQYGKPVDIWAIGCVMAE |
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| Kinase | 83714.m00243.AA | DYRK | 40-263 | 32 | 3e-34 | 120.12 | In-house | 1-226 (320) | Show / Hide |
Range on Protein: 40-263 Range on HMM: 1-226/320 Sequence Identity: 32% (77 aa) YNPLNIIGKGAFGVVF-CARAPTGDVVAIKKVLIDPRYKN---RELDIISTIKHH------NCITLRDSFRIQGRKKGEIFLNIVMDYYPMTLYDFTLNY | | .|||| || |. | |.. |||| . .|. . .|. |.. .. . .|. . |.| .. .| || . . | ||.| |. YEILEYIGKGSFGQVVKCWDHKTNEMVAIKIIRNNKRFHRQAQIEIKILEYLNQQDPDDKYHCVHMYDYFYHRN------HLCIVFELLSMNLYEFLKNN RNQRLYVPILYIKLFSYQLFAGLRYLHKR-RIVHRDIKPQNLLVNQ--ETGVLKICDFGSAKIIKPGDKSVSYIASRFYRAPELILDCQVYGPPIDIWAS . | . .. ... | .|.. .|..||| .|.| |.|| | ...| .|..||||. .. . .|| |||||||| || |. |. .||.| HFQGF-FSLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENIMLKQPRNKSTIKVIDFGSSCFEHQ--RIYTYIQSRFYRAPEVILGCP-YCYAIDMWSL GCVIAEAINSASPLFVSETSNGQINAIIKIFGQPNPE ||..|| . ||| |. . |.. |. ..| |... GCILAE-LFTGWPLFPGENEYDQLACIMEVLGMPPKW |
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| Kinase | 83714.m00243.AA | TyrKc | 40-323 | 21 | 8.2e-13 | -15.49 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 40-323 Range on HMM: 1-280/280 Sequence Identity: 21% (69 aa) YNPLNIIGKGAFGVVFCARAPTGDVVAIKKVLIDPRYKN--RELDIISTI--KHHNCITLRDSFRIQGRKKGEIF-----LNIVMDYYPM-TLYDFTLNY . ..| ||||.|. ... ||.|.. | . ||. | . . .| | . | . |||. | | ||| | | | |. .. ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN----FMYIEPLMIVMEYMPHGDLKDYLRKH RNQRLYVPILYIKLFSYQLFAGLRYLHKRRIVHRDIKPQNLLVNQETGVLKICDFGSAKIIKPG--------DKSVSY-IASR-----FYRAPELILDCQ |.. .. |..| .| .|||.....|||. | ||. . . ||.||| .. |. . .... .. ||| | . RPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYG VYGPPIDIWASGCVIAEAINSASPLFVSE----TSNGQ-INAIIKIFGQPNPED----FADYAHGNSVPTDVQQETTLEKVLPGHTPPDLIDLLKKCFIY .. . |.|. | .. | . . || . |. . . . | |.. . |... .. |.| . KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS----------------------F-VCCPDEMYQIMKQCWHE NPNERITAEQAMAHPCF .|..| | .. | || DPEDRPTFSEI--HECF |
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| Kinase | 83714.m00243.AA | CDKL | 277-323 | 38 | 6.1e-12 | 37.11 | In-house | 240-286 (286) | Show / Hide |
Range on Protein: 277-323 Range on HMM: 240-286/286 Sequence Identity: 38% (18 aa) DVQQETTLEKVLPGHTPPDLIDLLKKCFIYNPNERITAEQAMAHPCF .... .||| .|. . ..|..|||. .| ||.|.||.| || | EIEHMEPLEKRYPNKSNKKALDFMKKCLHMDPDERMTCEQLMHHPYF |
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| Kinase | 83714.m00243.AA | CAMK | 294-323 | 33 | 2.9e-11 | 31.8 | In-house | 396-425 (425) | Show / Hide |
Range on Protein: 294-323 Range on HMM: 396-425/425 Sequence Identity: 33% (10 aa) PDLIDLLKKCFIYNPNERITAEQAMAHPCF .. .||..|. ..|..|.|.||...|| . QECKDLIRKMLQVDPEKRMTIEQCLNHPWM |
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| Kinase | 83714.m00243.AA | DYRK | 278-323 | 28 | 9.1e-11 | 36.74 | In-house | 276-320 (320) | Show / Hide |
Range on Protein: 278-323 Range on HMM: 276-320/320 Sequence Identity: 28% (13 aa) VQQETTLEKVLPGHTPPDLIDLLKKCFIYNPNERITAEQAMAHPCF .. . .. .. ...|..|||....|..|||..||. || | PPGRRNWDPRHQ-CDDHQFKDFIKKCLQWDPHKRITPSQALQHPWF |
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| Kinase | 83714.m00243.AA | CDC2 | 280-323 | 32 | 4.7e-10 | 26.56 | In-house | 250-301 (301) | Show / Hide |
Range on Protein: 280-323 Range on HMM: 250-301/301 Sequence Identity: 32% (17 aa) QETTLEKVLPG--------HTPPDLIDLLKKCFIYNPNERITAEQAMAHPCF ... |.|..| ..|. ||||.. .|.|. ||.|..|..|| | KPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQHPYF |
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| Kinase | 83714.m00243.AA | MAPK | 40-70 | 42 | 1.5e-08 | 25.43 | In-house | 1-38 (328) | Show / Hide |
Range on Protein: 40-70 Range on HMM: 1-38/328 Sequence Identity: 42% (16 aa) YNPLNIIGKGAFGVVFCARAP-------TGDVVAIKKV |..| ||.||.|||. |. .|. |||||. YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKI |
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| Kinase | 83714.m00243.AA | ERK | 40-70 | 43 | 4.1e-07 | 22.75 | In-house | 1-37 (307) | Show / Hide |
Range on Protein: 40-70 Range on HMM: 1-37/307 Sequence Identity: 43% (16 aa) YNPLNIIGKGAFGVVFCAR-AP-----TGDVVAIKKV |. .. ||.||.|||. |. . ||. |||||. YQIIKQIGHGAYGVVCSAIDKEYCFDETGQKVAIKKI |
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| Kinase | 83714.m00243.AA | RCK | 40-69 | 41 | 5.5e-07 | 17.89 | In-house | 1-31 (298) | Show / Hide |
Range on Protein: 40-69 Range on HMM: 1-31/298 Sequence Identity: 41% (13 aa) YNPLNIIGKGAFGVVFCARA-PTGDVVAIKK |. .. .|.|..|.|. |.. ||..||||| YQIIKQLGDGTYGCVMKAQNKETGEIVAIKK |
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| Kinase | 83714.m00243.AA | Pkinase_Tyr | 144-185 | 40 | 3e-06 | 21.84 | Pfam | 116-156 (270) | Show / Hide |
Range on Protein: 144-185 Range on HMM: 116-156/270 Sequence Identity: 40% (17 aa) FSYQLFAGLRYLHKRRIVHRDIKPQNLLVNQETGVLKICDFG ...| .|. ||. ....|||. | ||. . | |||||| MCWQIAKGMEYLESKNCIHRDLAARNCLVTENN-VVKICDFG |
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| Kinase | 83714.m00243.AA | CDKL | 40-69 | 48 | 5.2e-05 | 13.07 | In-house | 1-31 (286) | Show / Hide |
Range on Protein: 40-69 Range on HMM: 1-31/286 Sequence Identity: 48% (15 aa) YNPLNIIGKGAFGVVF-CARAPTGDVVAIKK | | .| |. |||. | || .||||| YEKLGKVGEGSYGVVMKCRNKETGQIVAIKK |
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| Kinase | 83714.m00243.AA | Pkinase_Tyr | 40-91 | 23 | 0.015957 | 9.17 | Pfam | 1-65 (270) | Show / Hide |
Range on Protein: 40-91 Range on HMM: 1-65/270 Sequence Identity: 23% (15 aa) YNPLNIIGKGAFGVVFCARAP-----TGDVVAIKKVLIDPRYKN-------RELDIISTI-KHHN . .|.||||.|. ... |. ||.|.. . .. ||. | ... .|.| ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPN |
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