Gene 94962.m00287 (T.vaginalis)

94962.m00287

Species: T.vaginalis
Alias: 94962.m00287, TvagK0118
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag2

Sequence

Name Sequence Type Origin Length Description Download
94962.m00287.AA Protein None 399 None Fasta, JSON
94962.m00287.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of 94962.m00287.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 94962.m00287.AA CAMK 20-267 24 3.8e-118 382.49 In-house 1-425 (425) Show / Hide 
Range on Protein: 20-267
Range on HMM: 1-425/425
Sequence Identity: 24% (106 aa)

TVGDGAFSVVKLVKNIENN------------QYYACKIVPKARLN-------------------------TIHLEKRFEIEIRIAQQ-------MHHPGI
| | |.|..|||.......            | .|.||..| .|                          . . .|... ||.| ..       ..|| |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VELCDLLKD-------------------DNNYYVIM---EFCPNGEL----FQFIVDRNN---------------LSEDEAKPLFRQILEALQYVHSHGV
. | .   |                   |...| .|   |.|..|||    |..||.. .               ..|.||. .||||..|..| |||..
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

SHRDLKPENLLID-NL----------------GRIKISDFGLSIFVDSQG------------------------LVKTPCGSPCYAS-PECISG------
 ||||||||.|.| |                 . |||.|||.....|.                          . ||.||.|.|.. || ..|      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------QLYDGMTTDVWSAGVILYAMLTGQLPWKKR-------------NQAQLFKQIKSGDYT-IPDELSS-----------------------DATN
       . |.|  .|.||.|||||.||.| .|.                |. .||..|..|.|. .|...|                        .. .
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

MLTRLLTVDPKARITIEEALQHPWL
.. ..|.|||. |.|||..|.|||.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 94962.m00287.AA AMPK 15-267 43 2.3e-114 340.94 In-house 1-254 (254) Show / Hide 
Range on Protein: 15-267
Range on HMM: 1-254/254
Sequence Identity: 43% (111 aa)

YKFRGTVGDGAFSVVKLVKNIENNQYYACKIVPKARLNTIHLEKRFEIEIRIAQQMHHPGIVELCDLL-KDDNNYYVIMEFCPNGELFQFIVDRNNLSED
|    | | |.|  ||. . |  ... | ||  | ..      .| . ||.| . . || |. | . . .     ...||. ..|||| .|| .. |.|.
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

EAKPLFRQILEALQYVHSHGVSHRDLKPENLLIDNLGRIKISDFGLSIFVDSQGLVKTPCGSPCYASPECISGQLYDGMTTDVWSAGVILYAMLTGQLPW
||. .| ||. .. |.| |...||||||||||.|   .||| |||||       . || |||||||.|| |||.|| |  .|.|| |||||||| | || 
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

KKRNQAQLFKQIKSGDYTIPDELSSDATNMLTRLLTVDPKARITIEEALQHPWL
   |...|.| ||.|.|.||. ||..| ... ..|.|||  ||||..  .|||.
DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 94962.m00287.AA CAMKL 15-267 34 7.79999999999e-113 361.45 In-house 1-297 (297) Show / Hide 
Range on Protein: 15-267
Range on HMM: 1-297/297
Sequence Identity: 34% (103 aa)

YKFRGTVGDGAFSVVKLVKN-IENNQYYACKIVPKARLNTIHLEKRFEI------------EIRIAQQMH---HPGIVELCDLLKDDNN------YYVIM
|..  | | |.|..||| .. . ... .| ||. | ... .   |.  .            ||.| ....   || |. | . . ....      .| .|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EFCPNGE--LFQFIVDRNN----LSEDEAKPLFRQILEALQYVHSHGVSHRDLKPENLLIDNLG--RIKISDFGLSIFVDS-----QGLVKTPCGSPCYA
| |..||  ||..|| . .    ..|.||. .||||..|..| ||||. |||.||||.|.|. |   |||.|||.|.. .        . || ||||.|.
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

SPECISG--QLYDGMTTDVWSAGVILYAMLTGQLPWKKR--------NQAQLFKQIKSGDYTIP--DELSSDATNMLTRLLTVDPKARITIEEALQHPWL
.|| ..|  . |||  .|.||.|||||||..|.||..          |.  |...|..| | .|   ..| |. ... ..|.|.|. |.||.. ..|||.
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 94962.m00287.AA S_TKc 15-267 34 1.5e-101 344.57 SMART 1-231 (231) Show / Hide 
Range on Protein: 15-267
Range on HMM: 1-231/231
Sequence Identity: 34% (93 aa)

YKFRGTVGDGAFSVVKLVKNIENNQYYACKIVPKARLNTIHLEKRFEIEIRIAQQMHHPGIVELCDLLKDDNNYYVIMEFCPN--GELFQFIVDRNN---
|..  ..| |||..|....... ....|.||..          .... ||.| .. ||| || | |   | ...|..||.|..  |.||..|..|.    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LSEDEAKPLFRQILEALQYVHSHGVSHRDLKPENLLIDNLGRIKISDFGLSIFVDSQGLVKTPCGSPCYASPECISGQLYDGMTTDVWSAGVILYAM
   ..| .|. ...||..||.| ||||. ||||||||.|.|.  .|||.||||. ..      .| ||.| | .|| .    |..   |.|| |.||| |
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

LTGQLPWKKRNQAQLFKQIKSGDYTIPDELSSDATNMLTRLLTVDPKARITIEEALQ-------HPWL
|.|. |.   .....||.|.          |..| ... ..|..||. |.|. ||||       |||.
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 94962.m00287.AA MARK 15-267 39 2e-100 328.91 In-house 1-262 (262) Show / Hide 
Range on Protein: 15-267
Range on HMM: 1-262/262
Sequence Identity: 39% (104 aa)

YKFRGTVGDGAFSVVKLVKNIENNQYYACKIVPKARLNTIHLEKRFEIEIRIAQQMHHPGIVELCDLLK--DDNN-YYVIMEFCPNGELFQFIVDR--NN
||.  | | |....|||. ..  .. .| ||..| .||  .  | .. ||.| ....|| |..| .     . ..  |.||| ...|||...|. .    
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LSEDEAKPLFRQILEALQYVHSHGVSHRDLKPENLLIDNLG--RIKISDFGLSIFVDSQGLVKTPCGSPCYASPECISGQLYDGMTTDVWSAGVILYAML
|.|.||. .||||..|..| ||... |||.||||.|||  |   |||.|||.|| . .  . .| ||.| |..|| .... |||  .|.|| ||.||.|.
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

TGQLPWKKRN--QAQLFKQIKSGDYTIPDELSSDATNMLTRLLTVDPKARITIEEALQHPWL
.|..|..  .  . .|.|.| .|.|.||. .| .. |.. |||||.|. |.|||| ..|||.
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 94962.m00287.AA CAMK1 15-267 38 1.6e-92 269.23 In-house 1-276 (276) Show / Hide 
Range on Protein: 15-267
Range on HMM: 1-276/276
Sequence Identity: 38% (106 aa)

YKFRGTVGDGAFSVVKLVKNIEN---NQYYACKIVP-KARLNTIHLE--KRFEIEIRIAQQM---HHPGIVELCDLLKDDNNYYVIMEFCPNGELFQFIV
|.|. . | ||||.|.|....|.   .. || |.   |  . . .    ...| || | ..    .|| |. . .   .|| .| .|| . .||||  ||
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV

DRNNLSEDEAKPLFRQILEALQYVHSHGVSHRDLKPENLL---IDNLGRIK--ISDFGLSIFVDSQG-LVKTPCGSPCYASPECISG---QLYDGMTTDV
.. | .|..|  . .|||.|..| ||.|. ||||||||||   .|.   ||  |.||||| ..|..  | ||.||.| |  || . .   . || .. |.
EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYD-KACDM

WSAGVILYAMLTGQLPWKKRN-QAQLFKQIKSGDYTIP----DELSSD-ATNMLTRLLTVDPKARITIEEALQHPWL
||.|||.| .|.|  |    | ...||..||...|. |    |. |.  | . .. .|.|||| |.|.|..|.|||.
WSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase 94962.m00287.AA RAD53 15-267 33 2.3e-91 272.34 In-house 1-305 (305) Show / Hide 
Range on Protein: 15-267
Range on HMM: 1-305/305
Sequence Identity: 33% (102 aa)

YKFRGTVGDGAFSVVKLVKNIENNQYYACKIVPKARLN-----TIHLEKRFEIEIRIAQQMHHPGIVELCDLLKD-DNNYYVIMEFCPNGELFQFIVDRN
| .....| |.|..|||... .. | .| ||. | ...     ||  ..... |..| .  .|| |... |   . . .|| ..|.  .|||| .||...
YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNK

N----LSEDEAKPLFRQILEALQYVHSHGVSHRDLKPENLLIDNLG------------------RIKISDFGLSIFVDSQGLVKTPCGSPCYASPECISG
     ..||..| .|.|...|..| |. | .|||||||| |... .                   |||.||||| ||. . . || ||.| |  || | .
RCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVGEGSFMKTMCGTPQYVAPEVITS

Q---------------LYDGMTTDVWSAGVILYAMLTGQLPWK-KRNQ----AQLFKQIKS-GDYTI----PDELSSDATNMLTRLLTVDPKARITIEEA
.                | .   |.||.|.||| .|.| .|    . |     |||.|||. | |       |. |. | ..  ..|.|||..|.||.||
KGHNCYHENEERQVQVGY-TKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDEA

LQHPWL
|.|||.
LNHPWM
Kinase 94962.m00287.AA Pkinase 15-267 32 2.6e-91 314.43 Pfam 1-293 (293) Show / Hide 
Range on Protein: 15-267
Range on HMM: 1-293/293
Sequence Identity: 32% (96 aa)

YKFRGTVGDGAFSVVKLVKNIENNQYYACKIVPKARLNTIHLEKRFE-IEIRIAQQMHHPGIVELCDLLKDDNNYYVIMEFCPNG----ELFQFIV--DR
|.. ...| |.|..|.. ... ... .|.||..| . .   .. ..   ||.| . ..|| ||.| |   |....|..||.|..|    .|| .|   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

NNL--SEDEAKPLFRQILEALQYVHSHGVSHRDLKPENLLIDNLGRI----KISDFGLSIF--VDSQGLVKTPCGSPCYASPECISGQLYDGMTTDVWSA
...  ||.|.|  ..|||..|.| ||.|. ||||||||.|||| | |    ||.||||. .    ...  .|.||.| |..|| | |. |.|   |.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVILYAMLTGQLPWKKR------NQAQLFKQIKSGDYTIPDELS---------------------SDATNMLTRLLTVDPKARITIEEALQHPWL
|.||| ||.|..|.. .      .| |....|.....  . . .                     ...   ....|..||| |.|.|..|||||.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 94962.m00287.AA ULK 15-267 30 9.3e-85 287.89 In-house 1-324 (324) Show / Hide 
Range on Protein: 15-267
Range on HMM: 1-324/324
Sequence Identity: 30% (99 aa)

YKFRGTVGDGAFS-VVKLVKNIEN---NQYYACKIVPKARLNTIHLE-------KRFEIEIRIAQQMH---HPG--IVELCDLLKDD--NNYYVIMEFCP
|  .   | |.|  .|   .|...   |||.|||...|  .| . .|       . .. ||.| ....   ||   ||.| | ....  ||.| |||.|.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

NGELFQFIVDR---------NNLSEDEAKPLFRQILEALQYVHSHGVSHRDLKPENLLIDNL------------GRIKISDFGLSIFVDS----QGLVKT
 | |.|.|  .         ..|||.||.  |.||...... |.|.. |||.||.|.|| |             |..||.|||.. .||.    | . .|
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

PC------GSPCYASPECISGQL----YDGMTTDVWSAGVILYAMLTGQLP---WKKRNQA----QLFKQ-------IKSGDYTIPD-----ELSSDATN
 .      |.| | .|. ..||.    |.   .|.|| |.|.| ||.|. |   | ...|     .| ..       ||     .|.      .|..  .
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

MLTRLLTVDPKARITIEEALQHPWL
 . |.|..|.| ||..|| ..|||.
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase 94962.m00287.AA ULK 15-267 29 9.4e-84 284.56 In-house 1-329 (329) Show / Hide 
Range on Protein: 15-267
Range on HMM: 1-329/329
Sequence Identity: 29% (98 aa)

YKFRGTVGDGAFSVVKLVKNIEN----NQYYACKIVPKARLNTIHLE-------KRFEIEIRIAQQMH--------HPGIVELCDLLKDD--NNYYVIME
|  .   | |.| .|   .|...    |...|||...|  .| .  |       . .. ||.| ....        || ||.| | ....  ||.| |||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

FCPNGELFQFIVDR----------NNLSEDEAKPLFRQILEALQYVHSHGVSHRDLKPENLLIDNL------------GRIKISDFGLSIFVDS----QG
.|. | |.|.|  .          ..|||.||.  |.|||..... |.|.. |||.||.| ||.|             |..||.|||.. .||.    | 
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

LVKTPC------GSPCYASPECISGQL----YDGMTTDVWSAGVILYAMLTGQLP---WKKRNQA-----QLFKQ-------IKSGDYTIP-----DELS
. .|        |.| | .|. ..||.    |.  ..|.|| |.|.| ||.|. |   | .. |      .|...       ||.    .|     . .|
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

SDATNMLTRLLTVDPKARITIEEALQHPWL
..  . . |.|..|.| ||..|| ..|||.
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 94962.m00287.AA Ciliate-E2 15-267 26 5.9e-81 275.26 In-house 1-365 (365) Show / Hide 
Range on Protein: 15-267
Range on HMM: 1-365/365
Sequence Identity: 26% (100 aa)

YKFRGTVGDGAFSVVKLVKNIEN-----------------------NQYYACKIVPKARLNTIHLEKRFEIEIR----------IAQQMHHPGIVELCDL
|||    | |.|..|...|....                       ...|| ||. |  .. |  |..   ||.          | .|. || |... . 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

LK--DDNNYYVIMEFCPNGELFQFIVDR-----------NNLSEDEAKPLFRQILE---------------ALQYVHSHG-VSHRDLKPENLLIDNLGRI
 .  ||||.| .||.|  |.||..| ..           ....| |.| ...|||.               ||.| || . . |||.||||.|.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KISDFGLSIFVDSQ--------------------------------GLVKTPCGSPCYASPECISGQLYDG--------MTTDVWSAGVILYAMLTGQLP
||.||||| ..| .                                 ...| ||.| | .|| ..|. ||.           |.||.||||| ||.|..|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

WKKRNQAQLFKQIKSGDYTIP------------------DELSSDATNMLTR----LLTVDPKARIT-IEEALQHPWL
.        ..||| ... .|                  ...| .. ... .    .| .||. ||| .|..|.|||.
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 94962.m00287.AA Ciliate-E2-Unclassified 15-267 28 2.5e-80 273.16 In-house 1-352 (352) Show / Hide 
Range on Protein: 15-267
Range on HMM: 1-352/352
Sequence Identity: 28% (101 aa)

YKFRGTVGDGAFSVVKLVKNIENNQYYACKIVPKARLNT--------------IHLEKRF-----EIEIRIAQQ----MHHPGIVELCDLLKDDNNYYVI
||.  . | |.|..|.........|||| |.  |.. .               ......       .  .|.||    . || || ...  .|..| | .
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKY-NKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MEFCPNGELFQFIVDRNN-----------------LSEDEAK-----PLFRQILEALQYVHSHG-VSHRDLKPENLLIDNLG---RIKISDFGLSIFVD-
||.|..|.|.|.| .|..                 ..| .||      .|.|||..|.| |. . . |||.||||.|.|| |   .|||.|||.|.. . 
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

---------------SQGLVKTPCGSPCYA----SPECISGQLYDGMT---TDVWSAGVILYAMLTGQLPWKKRNQAQ----------------LFKQIK
               .| . .| ||.|.|     .||.. || ||...    |.|| |||||.||.|..| . .|. |                |...||
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

SGDYT--------IPDELSSDATNMLT----RLLTVDPKARITIEEALQHPWL
 ...         ||. .|  | ....    ..| ..|. |||.|..|.|||.
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 94962.m00287.AA TyrKc 15-267 22 5.2e-15 20.06 SMART 1-280 (280) Show / Hide 
Range on Protein: 15-267
Range on HMM: 1-280/280
Sequence Identity: 22% (65 aa)

YKFRGTVGDGAFSVVKLVKNIENNQYYACKIVPKARLNTIHLEKRFEIEIRIAQQM--HHPGIVELCDLLKDD-------NNYYVIMEFCPNGELFQFIV
 ..  . | ||| .| . . .   .  | | . .        .. |  |.||  .   ||| || |     ..         ....||..|.| | ... 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

DRNN-LSEDEAKPLFRQILEALQYVHSHGVSHRDLKPENLLIDNLGRIKISDFGLSIFVDSQ-------GLVKT----PCG--SPC-YASPECISGQLYD
.. . |. ..      || .  .| ||... ||||   | |... ...|||||||| ....           ..     .    |    .||||    . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

GMTTDVWSAGVILYAMLT-GQLPWKK-----RNQAQLFKQIKSGDYTIPDEL---------SSDATNMLTRLLTVDPKARITIEEALQHPWL
   .|||| || .. ..| || |.        . .......|.|..  . .          ...  .. ..    ||. | | .|   |  .
-TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 94962.m00287.AA Pkinase_Tyr 83-228 25 5.9e-09 30.95 Pfam 75-232 (270) Show / Hide 
Range on Protein: 83-228
Range on HMM: 75-232/270
Sequence Identity: 25% (40 aa)

KDDNN--YYVIMEFCPNGELFQFIVD----RNNLSEDEAKPLFRQILEALQYVHSHGVSHRDLKPENLLIDNLGRIKISDFGLSIFV--DSQG-LVKTPC
...    .|..||..|.| |  .  .    ...|.  .     .|| ....| .|..  ||||   | |... . .||.||||.  .  |..   ... .
DQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGG

GSP-CYASPECISGQLYDGMTTDVWSAGVILYAMLT-GQLP-WKKRNQAQLFKQI-KSG
  |    .||||.   .    .|||| || .. ..| |. | ..    ......| ..|
KLPIKWMAPECINYGKFT-TKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDG