80754.m00121

Species: T.vaginalis
Alias: 80754.m00121, TvagK0853
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
80754.m00121.AA Protein None 323 None Fasta, JSON
80754.m00121.kin_dom Protein Kinase Domain None 251 None Fasta, JSON

Protein domain

Protein domains of 80754.m00121.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 80754.m00121.AA S_TKc 20-273 25 5.6e-62 213.14 SMART 1-231 (231) Show / Hide
Range on Protein: 20-273
Range on HMM: 1-231/231
Sequence Identity: 25% (67 aa)

YILIDIIGYGGFANVFKVYSQHFKQYFAAKVCYIGSDAVTQNLQSFMAEVGALSKIYHSSVINIYSYFDDNSYLFIILDYCPN--GSVLDYIKTHPH---
| ....|| |.|. |.|..  . ....| |.            .... |.  |.|  |  ....| .|.| ..|.....||..  |...|||| ...   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---IETSLIFDWLVQTTEGLVACHNIGISHRDIKPSNLLIDSYNRIKIGDFGLAVIAEKSQMIARFGGSPIFYSPEMVMKKKFDPFKADVWALGITFYRL
   .    .  .. |. ..|  ||. || |||.||.|.|.|.  .|||.||||| .         | |.| . .||..   .....|.|.|..|...| .
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

IFGKIPYTAKSNDELVEQIKCGRIIIPATCDAKLSVVLEMILKPNPDERPTAADVLQ------LLKYI
. |. |.     ... ..|.          .  .   .. .|. .|..|||| ..||      .  ..
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 80754.m00121.AA MARK 20-268 28 3.2e-53 172.39 In-house 1-258 (262) Show / Hide
Range on Protein: 20-268
Range on HMM: 1-258/262
Sequence Identity: 28% (76 aa)

YILIDIIGYGGFANVFKVYSQHFKQYFAAKVCY---IGSDAVT-QNLQSFMAEVGALSKIYHSSVINIYSYFD--DNSY-LFIILDYCPNGSVLDYIKTH
| ..  || |..| | .. ..| .. .| |.     .       |.....| |.  ..|. |  .|  . ...  ...  ...|..|...|...|||| |
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLN----DPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAH

-----PHIETSLIFDWLVQTTEGLVACHNIGISHRDIKPSNLLIDSYN--RIKIGDFGLAVIAEKSQMIARFGGSPIFYSPEMVMKKKFDPFKADVWALG
     .. |.  ||    |  ...  ||...| |||||| |.|||. .   ||| |||.... .  |.  .| |.| . .||.. ||. | .|.|.|.||
PNGRLHEEEARRIF---RQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLG

ITFYRLIFGKIPYTAKS--NDELVEQIKCGRIIIPATCDAKLSVVLEMILKPNPDERPTAADVLQ
.  | .. |. |. ...  . || ..|  |.  ||    ...   .  .|..||.||||. ....
VVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMK

Kinase 80754.m00121.AA CAMK 25-268 16 2e-52 166.85 In-house 1-421 (425) Show / Hide
Range on Protein: 25-268
Range on HMM: 1-421/425
Sequence Identity: 16% (68 aa)

IIGYGGFANVFKVYSQHFK------------QYFAAKV----------------CYIGSDAV----------TQNLQSFMAEVGALSK-------IYHSS
..| |.|. |....  . .            | .|.|.                || . |             ....... |.  ..|       . |  
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCY-KIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPN

VINIYSYFDD-------------------NSYLFIIL---DYCPNG----SVLDYIKTHPH---------------IETSLIFDWLVQTTEGLVACHNIG
.|..| ...|                   ........   .||..|     ..|||. |..               .. .    .  |  ...  ||. .
IIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

ISHRDIKPSNLLIDSY-----------------NRIKIGDFGLAVIAEK------------------------SQMIARFGGSPIFYS-PEMVMK-----
| |||.|| |.|.|.                  | ||| |||.| . ..                         |.   | |.| . . ||.. .     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------KKFDPFKADVWALGITFYRLIFGKIPYTAK-------------SNDELVEQIKCGRII-IPAT-----------------------CDAKLS
        |. ...|.|.|..|.  | .  |. |. ..             .  || |.|. |.   .|                         ...   
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

VVLEMILKPNPDERPTAADVLQ
  .  .|...|..|.|....|.
DLIRKMLQVDPEKRMTIEQCLN

Kinase 80754.m00121.AA CAMKL 20-268 22 4.1e-52 164.52 In-house 1-293 (297) Show / Hide
Range on Protein: 20-268
Range on HMM: 1-293/297
Sequence Identity: 22% (66 aa)

YILIDIIGYGGFANVFKVYS-QHFKQYFAAKVCYIGSDAV-TQNLQSFMA-----------EVGALSKIY---HSSVINIYSYFDDNSY------LFIIL
|.... .| |.|. |      .. ..  | |.  .      ..... .             |.  ....    |  .| .|  ... ..      .....
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

DYCPNGS--VLDYIKTHPH----IETSLIFDWLVQTTEGLVACHNIGISHRDIKPSNLLIDSYN--RIKIGDFGLAVIAEK-----SQMIARFGGSPIFY
 ||..|.   .|||. |.|    .. .       |  ...  ||. || |||||| |.|.|. .   ||| |||.. . ..      |.   | ||| . 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

SPEMVMK--KKFDPFKADVWALGITFYRLIFGKIPYTAK--------SNDELVEQIKCGRIIIPAT--CDAKLSVVLEMILKPNPDERPTAADVLQ
.||.. .  |..| .|.|.|..|.. | ...|. |  .          . .| ..|.||   .|     .  .   .  .|..||..|||. ....
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMN

Pkinase 80754.m00121.AA Pkinase 20-270 22 3e-49 174.71 Pfam 1-293 (293) Show / Hide
Range on Protein: 20-270
Range on HMM: 1-293/293
Sequence Identity: 22% (68 aa)

YILIDIIGYGGFANVFKVYSQHFKQYFAAKVCYIGSDAVTQNLQSFMA--EVGALSKIYHSSVINIYSYFDDNSYLFIILDYCPNG----SVLDYIK--T
| .. .|| |.|. |.| . .   . .| |.     ..  . .|.     |.  . .. |  .. .| .| |.... ....||..|    .  |||.   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

HPHI--ETSLIFDWLVQTTEGLVACHNIGISHRDIKPSNLLIDSYNRI----KIGDFGLAVI--AEKSQMIARFGGSPIFYSPEMVMKKKFDPFKADVWA
|  .  .   . ... |. .||  ||. || |||.||.|.|||. . |    ||.|||||      ...    | |.| . .|| ... . .. |.|.|.
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGITFYRLIFGKIPYTAK------SNDELVEQIKCGRIIIP--ATCD-------------------AKLSVVLEMILKPNPDERPTAADVLQL--L
.|...| ...|. |.  .      . ......|.....  .   .|.                     .  ... .|...| .||||...||   .
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 80754.m00121.AA Ciliate-E2-Unclassified 20-272 20 1.9e-45 155.59 In-house 1-352 (352) Show / Hide
Range on Protein: 20-272
Range on HMM: 1-352/352
Sequence Identity: 20% (71 aa)

YILIDIIGYGGFANVFKVYSQHFKQYFAAKVCYIGSDAVTQNLQSF----------MAEVG-------------ALSKIYHSSVINIYSYFDDNSYLFII
|..| .|| |||. |.|..    | ...|.   . .  . |... .          | .                |. ..|  ... . .| |  ...|.
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

LDYCPNGSVLDYIKTHPH-----------------IETSLIF-----DWLVQTTEGLVACHNIG-ISHRDIKPSNLLIDSYN---RIKIGDFGLAVIAE-
..||..|. ..|||  ..                 ..   .      ... |  .||  .|  . | ||||||.|.|.|. .   .||| |||..   . 
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

---------------KSQMIARFGGSPIFY----SPEMVMKKKFDP---FKADVWALGITFYRLIFGKIPYTAKSNDE---------------LVEQIKC
               |.||.  | |.|..     .||. .... |    .|.|.|.||. .| ..||. |. ... ..                ..|...
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

GR-------------IIIPATCDAKLSVVLEMILKPNPDERPTAADVLQLLKY
 .              ... ..   ..  |  .|| ||..|.|. ..|.    
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase 80754.m00121.AA Ciliate-E2 20-272 19 1.5e-44 150.84 In-house 1-365 (365) Show / Hide
Range on Protein: 20-272
Range on HMM: 1-365/365
Sequence Identity: 19% (75 aa)

YILIDIIGYGGFANVFKVYSQHFKQYFA----------------AKVCYIGSDAVTQN-LQSFMAEVGALSKIY----------------HSSVINIYSY
|..| .|| |.|. |.|.     .. ||                .|. ..    . .| ..... |   . .|                 |  .|..| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FD--DNSYLFIILDYCPNGSVLDYIKTHPH--------------IETSLIFDWLVQTT------------EGLVACHNIG-ISHRDIKPSNLLIDSYNRI
|   |.........||  |. .|||| ...               | . |.  ..|              ..|  .|. . | ||||||.|.|.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KIGDFGLAVIAEKS--------------------------------QMIARFGGSPIFYSPEMVMKKKFDP--------FKADVWALGITFYRLIFGKIP
|| ||||. .. ..                                .|. .. |.| . .||....|| |         .|.|.|.||...|...||| |
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

YTAKSNDELVEQIKCGRIIIP------------------ATCDAKLSVVLEM----ILKPNPDERPT-AADVLQLLKY
.         .||| . | .|                    .. .    .      .|. .|..|.| . ..|.    
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase 80754.m00121.AA PLK1 20-272 28 3.1e-43 139.83 In-house 1-253 (253) Show / Hide
Range on Protein: 20-272
Range on HMM: 1-253/253
Sequence Identity: 28% (72 aa)

YILIDIIGYGGFANVFKVYSQHFKQYFAAKVCYIGSDAVTQNLQSFMAEVGALSKIYHSSVINIYSYFDDNSYLFIILDYCPNGSVLDYIKTHPHIETSL
|     .| ||||  . .  .. |. ||.||         .  .    |.    .. |  .......|.|.....|.|. |   |...  |    |    
YEKGRFLGKGGFAHCYEIRDKDTKEVFAGKVVPKSLLIKQHQRDKMTQEIQIHRQLHHRHIVKFHHFFEDKQNVYIVLELCRRRSLMELHKRRKAITEPE

IFDWLVQTTEGLVACHNIGISHRDIKPSNLLIDSYNRIKIGDFGLAVIAEKS-QMIARFGGSPIFYSPEMVMKKKFDPFKADVWALGITFYRLIFGKIPY
   .. |  ||    ||  | |||.|  || ..   ..||||||||   |..       .| | .  || |..||   |  |.|..|  .| |.||. |.
CRYYMYQIVEGCQYLHNNKIIHRDLKLGNLFLNDHLQVKIGDFGLATKCEYDGERKKTLCGTPNYIAPE-VLNKKGHSFEVDIWSIGCIMYILLFGQPPF

TAKSNDELVEQIKCGRIIIPATCDAKLSVVLEMILKPNPDERPTAADVLQLLKY
 .|. .|   .||     ||    .  . ... .|.|.|..|||.  ||.   .
ETKCLKETYSRIKKNEYRIPSHISQPAAQLIRKMLDPDPTRRPTIEQVLNDEFF

Kinase 80754.m00121.AA ULK 20-231 22 3.4e-37 129.56 In-house 1-278 (324) Show / Hide
Range on Protein: 20-231
Range on HMM: 1-278/324
Sequence Identity: 22% (63 aa)

YILIDIIGYGGFA-NVFKVYSQHF---KQYFAAKVCYIGSDAVTQNL-------QSFMAEVGALSKIY------HSSVINIYSYFDDN--SYLFIILDYC
|.|....| | |.  |.| . .     .||.|.|.  . .    .|.       |... |.  . |.       |  ..  | .| .    ...||..||
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNH-HIVKLYDWFETSNHNNIYIIMEYC

PNGSVLDYIKTHPH---------IETSLIFDWLVQTTEGLVACHNIGISHRDIKPSNLLIDSYN------------RIKIGDFGLAVIAEKSQMIARFG-
. |   .|||.. .         .. . .   . |  .|. . |. .| ||||||.|.||   .            ..||.|||.| . .. .| .    
NGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

---------GSPIFYSPEMVM----KKKFDPFKADVWALGITFYRLIFGKIP---YTAKSND----ELVEQ-------IK
         |.|.. .|. ..    .|... .|.|.| ||. || ...|| |   . . . .    .|...       ||
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIK

Kinase 80754.m00121.AA ULK 20-231 23 5.7e-36 123.08 In-house 1-268 (329) Show / Hide
Range on Protein: 20-231
Range on HMM: 1-268/329
Sequence Identity: 23% (63 aa)

YILIDIIGYGGFANVFKVYSQHFK----QYFAAKVCYIGSDAVTQNLQ-------SFMAEVGALSKIY--------HSSVINIYSYFDDN--SYLFIILD
|.|....| | |. |.| . .  |    ...|.|.  . .    .|.|       ... |.  . |.         |  ..  | .| .    ...||..
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCPNGSVLDYIKTHPH----------IETSLIFDWLVQTTEGLVACHNIGISHRDIKPSNLLIDSYN------------RIKIGDFGLAVIAEKS----Q
||. |   .|||.. .          .. . .   . |  .|. . |  .| ||||||.| ||.  .            ..||.|||.|   ...    |
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

MIARFG------GSPIFYSPEMVM----KKKFDPFKADVWALGITFYRLIFGKIPYTAKSNDELVEQIK
|.  .       |.|.. .|. ..    .|... .|.|.| ||. || ...|| |. |  . ....||.
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQII

Kinase 80754.m00121.AA TKL 26-270 17 1.8e-33 117.52 In-house 1-364 (364) Show / Hide
Range on Protein: 26-270
Range on HMM: 1-364/364
Sequence Identity: 17% (65 aa)

IGYGGFANVFKVYSQHFK--------QYFAAKVCYIGS-DAVTQNLQS---------------------FMAEVGALSKIY--HSSVINIYSYFDDNSY-
|| |||. |.| . .           .  | |.  . . |  | |.|                      |  |. .....   |  .. .. |  .... 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------LFIILDYCPNGSVLDYIKTHPHIETSLIFDWLVQTTEGLVACHNIG--------ISHRDIKPSNLLIDSYNR--------------IK
            |.|. .|||.|| |.|.        .....|  ..  |.   |. .        | |||.|..|.|.|. ..              .|
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

IGDFGLAVIAEKSQ--------------------MIARFGGSPIFYSPEMVMKKKFDP---------------FKADVWALGITFYRLIFGKIPYT-AKS
|.||||.   ..|.                    .  . .|.| . .||. ... ...                |.||.. || .. .. ...||   ..
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPY

NDEL---------VEQIKCG-RIIIP------------ATCDAKLSVVLEMILKPNPDERPTAADVLQLL
....         .  .. | |  ||             .|.  ..  ...  ...|..||.. ..|. |
MPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase 80754.m00121.AA STE 20-273 18 8e-32 109.7 In-house 1-359 (359) Show / Hide
Range on Protein: 20-273
Range on HMM: 1-359/359
Sequence Identity: 18% (67 aa)

YILIDIIGYGGFANVFKVYSQ------HFKQY---------FAAKVCYIGSDAV--------------TQNLQSFMAEVGALSKIY--HSSVINIYSYFD
. .|..|| |.|  |.| .        . ..          .| |.  . ..                ....|... |.  ..|    |  ... | .. 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DN-------SYLFIILDYCPNGSVLDYIK-------THP-------HIETSLIFDWLVQTTEG-LVACHNIGISHRDIKPSNLLIDSYNRIKIGDFGLAV
..       ..|.|.. |...||. | ||       ...       ... |.|   ..|. .| |   |. .| ||||||.| |.     .|. |||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

IAEK-----------------SQMIARFGGSPIFYSPEMVMK------KKFDPFKADVWALGITFYRLIFGKIPY---TAKSNDELVEQIK---------
. ..                 .|.   | |.| . .||....      |. | .|.|.| ||.|   .. || |.   .  ..  .  . .         
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYD-TKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

----CGRIIIP-------------------ATCDAKLSVVLEMILKPNPDERPTAADVLQL-LKYI
     .   .|                     .  ..   ..  |. .|..|||| . |.   . |
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI

Kinase 80754.m00121.AA TyrKc 20-270 22 1.2e-17 62.44 SMART 1-280 (280) Show / Hide
Range on Protein: 20-270
Range on HMM: 1-280/280
Sequence Identity: 22% (65 aa)

YILIDIIGYGGFANVFK-VYSQHFKQYFAAKVCYIGSDAVTQNLQSFMAEVGALSKI--YHSSVINIYSYFDDN-------SYLFIILDYCPNGSVLDYI
  |....| | |  |.| ...    .  | |..  ..      .. || |   ..|.   |  ....| .  .          |.|.. |.|.|. .||.
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

KTHPH-IETSLIFDWLVQTTEGLVACHNIGISHRDIKPSNLLIDSYNRIKIGDFGLAVIAEKS--------QMIARF--GG---SPIF-YSPEMVMKKKF
. | . . ..   .. .|  .|    |  .. |||.   | |... ...||.||||.   .             ..   ||    ||  ..||  ...||
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

DPFKADVWALGITFYRLI-FGKIPYTA-----KSNDELVEQIKCG-RIIIPAT--------CDAKLSVVLEMILKPNPDERPTAADVLQLL
  .| |||. |.. . .  .|. ||       .||.|..|..| | |  .|.         | ...  . ..  . .|..||| ... ...
T-TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase 80754.m00121.AA Pkinase_Tyr 56-270 24 2.5e-12 42.36 Pfam 39-270 (270) Show / Hide
Range on Protein: 56-270
Range on HMM: 39-270/270
Sequence Identity: 24% (58 aa)

DAVTQN--LQSFMAEVGALSKI-YHSSVINIYSYFD-DNSY--LFIILDYCPNGSVLDYIKTH----PHIETSLIFDWLVQTTEGLVACHNIGISHRDIK
.|  ..  ...||.|.  .... .|  ... |     .     ..|.. |.|.|. ||| ..|    ... .. . .. .|  .|.   ..... |||. 
GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLA

PSNLLIDSYNRIKIGDFGLAVIA-EKSQMIARFGG---SPIF-YSPEMVMKKKFDPFKADVWALGITFYRLIF-GKIP-YTAKSNDELVEQI--KCGRII
  | |... | .||.|||||    ....   | .|    ||. ..||  . .||   | |||. |.. . ..  |..| |   || |..|.|  . .|  
ARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFT-TKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMP

IPATCDAKLSVVLEMILKPNPDERPTAADVLQLL
.|  | ...  .. .  ...|..||| ..... |
CPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL