Gene 87328.m00164 (T.vaginalis)

87328.m00164

Species: T.vaginalis
Alias: TvagK0682, 87328.m00164
External Links:
Annotation:

Classification

Group: Other
Family: NEK
Subfamily: NEK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
87328.m00164.AA Protein None 1077 None Fasta, JSON
87328.m00164.kin_dom Protein Kinase Domain None 255 None Fasta, JSON

Protein domain

Protein domains of 87328.m00164.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 87328.m00164.AA NEK 4-258 47 3.2e-155 521.96 In-house 1-286 (286) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-286/286
Sequence Identity: 47% (137 aa)

YEQIKVLGEGGFAKAFLVKRKTDRLL-----CVAKSVKLSGLSEKEKKEAI-SEVNVLSALKHPNIVRYIESFNE--SGFLYIIMEYAD-GGDLSQK---
|| ||..|.| | |...|.|| |        .| | ......|||||..|. .||..|. |||||||.|..|| |  ...|.|.|||.. ||||.||   
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS

IEKN--GRKSFSEDEVLRIFTQLALAIKYIHDR-----KILHRDLKGQNVFLMKDGS----VKLGDFGIAKVLDHTMQFYNT-QIGTPYYLSPEMCQGKN
|.|.   .| |.|......|.|..||.||.|||     ||||||.| ||.|| |...    ||.|||||.|||.||... .| |.|||||.|||.||.| 
IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNKP

YNSKTDIWSFGCIMYEMCTL--HHAFEGR--NINNLLFNIVRG-NITPISTQ--YSADLRNLINSMLSKDPKLRPTATEIVKKPII
||.| ||||.||. ||||||   |.||.   |...| ..|..| .  ||. .  || ||.|||..|| |||..||....| ..|.|
YNNKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase 87328.m00164.AA NEK1 4-258 49 8.4e-140 470.74 In-house 1-276 (276) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-276/276
Sequence Identity: 49% (137 aa)

YEQIKVLGEGGFAKAFLVKRKTDRLLCVAKSVKLSGLSEKEKKEAISEVNVLSALKHPNIVRYIESFNESGF--LYIIMEYADGGDLSQKIEKN--GRKS
|. ||..||| | ||.|||.| |. ..| |. ...  .|||. |.  ||..|. .||||||.| ||| | |   |||.|||.||||| |||..     |.
YHYIKQIGEGSFGKAWLVKHKEDGQHYVIKEINVMKMQEKEREESMNEVAILAKMKHPNIVKYKESFEENGCGILYIVMEYCDGGDLMQKINRQKRKGKL

FSEDEVLRIFTQLALAIKYIHDRKILHRDLKGQNVFLM--KDG---------------SVKLGDFGIAKVLDHTMQFYNTQIGTPYYLSPEMCQGKNYNS
||||. .  |.|. || ..||||||||||.| ||.||   |.|                |||||||||..| ||| . .| ||||||||||.|| | || 
FSEDQIMHWFCQICLALNHIHDRKILHRDIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGIARMLNHTMEYACTCIGTPYYLSPEICQNKPYNN

KTDIWSFGCIMYEMCTLHHAFEGRNINNLLFNIVRGNITPISTQYSADLRNLINSMLSKDPKLRPTATEIVKKPII
|.|||| ||. || ||| |.||..|  ||   |..| ..||.  || .|..|. .|....|..|| .. | ..|.|
KSDIWSLGCVLYELCTLKHPFEANNWKNLVLKICQGTYPPIPPHYSYELQSLVSQMFKRNPRHRPSVNQILERPFI
Kinase 87328.m00164.AA NEK8 4-258 41 1.2e-131 378.13 In-house 1-278 (278) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-278/278
Sequence Identity: 41% (114 aa)

YEQIKVLGEGGFAKAFLVKRKTDR--LLCVAKSVKLSGLSEKEKKEAISEVNVLSALKHPNIVRYIESFNESGFLYIIMEYADGGDLSQKIEKNGRKSFS
|| | |.| | |  . |  || |    | . | . ....||||   | .|..||| | ||||. |...| | . | | ||||||| | |.| ..  |.|.
YERIRVVGRGAFGICWLYRRKEDQSHHLVIWKQINMHRMSEKERQMAQNEIQVLSMLQHPNIISYYDHFMEDNTLMIEMEYADGGTLYQMIQHQQNKLFE

EDE-----------------VLRIFTQLALAIKYIHDRKILHRDLKGQNVFLMKD-GSVKLGDFGIAKVLDHTMQFYN--TQIGTPYYLSPEMCQGKNYN
| .                 .|  |.|  .|. ..|.  ||||||| ||.|. .. . ||.|||||.|..      .   | .|||||.|||||.|| ||
EERQLKQVNHCFNIYFNEQMILWYFFQMCSAVHHMHQHNILHRDLKTQNIFMTRHRMVVKIGDFGISKIMNTKYHMQTTKTVVGTPYYMSPEMCEGKPYN

SKTDIWSFGCIMYEMCTLHHAFEGRNINNLLFNIVRG-NITPISTQYSADLRNLINSMLSKDPKLRPTATEIVKKPII
 | |.|. ||. ||||.|  |||. |  .|   |... . .||| .||...| |. . |..||  ||.| .| . | .
QKSDMWALGCVLYEMCCLKRAFEASNLPALVWKIMQCRAYEPISDHYSNEMRMLVHNCLQQDPEQRPSASQIMAMPLC
Kinase 87328.m00164.AA NEK4 4-258 44 2.2e-104 353.11 In-house 1-257 (257) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-257/257
Sequence Identity: 44% (114 aa)

YEQIKVLGEGGFAKAFLVKRKTDRLLCVAKSVKLSGLSEKEKKEAISEVNVLSALKHPNIVRYIESFN-ESG-FLYIIMEYADGGDLSQKIEKNGRKSFS
|. .|| | | .   .||. . |.   | | ..|   | .|.|.|  |...|| ||||||| | ||.  | | ||||.| . .|||| .|  .   .  .
YCHMKVVGKGSYGEVWLVRHRRDKKQYVMKKMFLKNASRRERKAAEHEAQLLSQLKHPNIVEYKESWEIENGQFLYIVMGFCEGGDLYRKLKQQKNQFLE

EDEVLRIFTQLALAIKYIHDRKILHRDLKGQNVFLMKDGSVKLGDFGIAKVLDHTMQFYNTQIGTPYYLSPEMCQGKNYNSKTDIWSFGCIMYEMCTLHH
|  |.  | | |.|  |.|...||||||| ||.|| |   .|.|||||..||.   ..  | ||||||.|||.   . |. | |||| || .||| || |
EYQVVEWFVQIAMALQYMHEKHILHRDLKTQNIFLTKKNIIKIGDFGISRVLNNHCDMAKTMIGTPYYMSPECFGNRPYDYKSDIWSLGCCVYEMITLKH

AFEGRNINNLLFNIVRGNITPISTQYSADLRNLINSMLSKDPKLRPTATEIVKKPII
||. ...| |.. |. |   |.. .|| || ||.  ||.| |. ||   .| ..| |
AFDAKDMNSLIYQIIQGQPPPMPPNYSQDLQNLVYQMLEKQPTKRPSIFDIFQMPYI
Kinase 87328.m00164.AA S_TKc 4-258 30 8.6e-95 322.14 SMART 1-231 (231) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-231/231
Sequence Identity: 30% (83 aa)

YEQIKVLGEGGFAKAFLVKRKTDRLLCVAKSVKLSGLSEKEKKEAISEVNVLSALKHPNIVRYIESFNESGFLYIIMEYADG--GDLSQKIEKNGR----
|| ....|.|.|.| .... | .  ..  | .|         . ...|...|.  .|||||.....| . ..||..|||.||  ||| . |.|.||    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

KSFSEDEVLRIFTQLALAIKYIHDRKILHRDLKGQNVFLMKDGSVKLGDFGIAKVLDHTMQFYNTQIGTPYYLSPEMCQGKNYNS-KTDIWSFGCIMYEM
. |.| .. ... |...|..|.|...|.||||| .|..| .   .|..|||.|..|       .|..|||.|..||..    |.  | |.||.|||.|||
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

CTLHHAFEGRNINNLLFNIVRGNITPISTQYSADLRNLINSMLSKDPKLRPTATEIVK-------KPII
..    |.     ...|....          | .....|. .| |||. |||| |. .        | .
LCGYPPFP---QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 87328.m00164.AA Pkinase 4-258 28 1.5e-85 295.33 Pfam 1-293 (293) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-293/293
Sequence Identity: 28% (84 aa)

YEQIKVLGEGGFAKAFLVKRKTDRLLCVAKSVKLSGLSEKEKKEAIS--EVNVLSALKHPNIVRYIESFNESGFLYIIMEYADGG----DLSQKIE--KN
|. ....|.|.|.. .. ..| .. . . | .|... .........   |. ..  |.||||||....| ... .|..|||..||    ||.  |.  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GRKSFSEDEVLRIFTQLALAIKYIHDRKILHRDLKGQNVFLMKDGSV----KLGDFGIAKVL-DHTMQFYNTQIGTPYYLSPEMCQ-GKNYNSKTDIWSF
|. .|||.|. ....|.. ...|.|...|.||||| .|... ..| .    |..|||.||..     . ..|  |||.|..|| .. |. | .| |.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GCIMYEMCTLHHAFEGR----NINNLLFNIVRGNITPISTQYS-----------------------ADLRNLINSMLSKDPKLRPTATEIVKKPII
|||.|||.. .  | |.    | .. .. |.|   .|.. ...                        ... .|...| |||| ||||..|.. | .
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 87328.m00164.AA NEK-Unclassified 4-258 39 1.7e-82 272.91 In-house 1-258 (258) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-258/258
Sequence Identity: 39% (103 aa)

YEQIKVLGEGGFAKAFLVKRKTDRLLCVAKSVKLSGLSEKEKKEAISEVNVLSALKHPNIVRYIESFNESGFLYIIMEYADGGDLSQKIEKNGRK--SFS
|..|  || ||    .||. .  .   | .  |      | ||     . .|| |.|| || | .|| |   |.   .| |||.| ..| |   |   | 
YDKITTLGQGGGGAVYLVRHQISKRHLVQQISK-----RKKKKKRQNKIIILSQLRHPHIVTYHDSFFENAKLFYTQDYCDGGNLDRRIQKHRKKNEPFD

EDEVLRIFTQLALAIKYIHDRKILHRDLKGQNVFLMKDGSVKLGDFGIAKVLDHTMQFYNTQIGTPYYLSPEMCQGKNYNSKTDIWSFGCIMYEMCTLHH
|  . . . |.  |. ||| |||.||||| ||.|| .|  | .|||||....|||     | .||. ..||| || . || . |.|| |||.|||||   
EGRIMQWCIQMIMAVQYIHQRKIIHRDLKPQNIFLTDDDTVSMGDFGISRIMDHTRDKARTCVGTMCWMSPEVCQDQPYNNRSDVWSLGCIIYEMCTCEP

AFEGRNINNLLFNIVRGNI------TPISTQYSADLRNLINSMLSKDPKLRPTATEIVKKPII
.|  .|.  ... |...         |.|  ||.|| ..|  || ...  || |||||  . |
FFDTHNMGEVYMKIKQDDNRLEEALEPVSKTYSTDLQQVIRFMLRRNFQQRPSATEIVEQDYI
Kinase 87328.m00164.AA NEK2 4-258 35 5.1e-82 275.97 In-house 1-319 (319) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-319/319
Sequence Identity: 35% (114 aa)

YEQIKVLGEGGFAKAFLVKRKTDRLLCVAKSVKLSGLSEKEKKEAISEVNVLSALKHPNIVRYIESF--NESGFLYIIMEYADGGDLSQKIEK--NGRKS
||  ...|.| | .   |.|| |  . | |  .   . |||.   .||.|.|. |||||||||       ..  |||.|||  |||||| | |  . |. 
YEVLYTIGNGSFGRCRKVRRKSDGKILVWKEICYGHMQEKECQMLVSECNILRQLKHPNIVRYYDWIIDRQNSTLYIVMEYCEGGDLSQMIKKCRKERQY

FSEDEVLRIFTQLALAIKYIHD---------------------RKILHRDLKGQNVFLMKDGS-------------------------------------
. |  ..||..|| .| . .|                      . |||||.|  |.||  |..                                     
MEEEFIWRIMFQLCTALQECHNGVELPTLTTIYDRMKPRIDGKHTILHRDIKPANIFLDYDHNDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQ

--VKLGDFGIAKVLDHTMQFYNTQIGTPYYLSPEMCQGKNYNSKTDIWSFGCIMYEMCTLHHAFEGRNINNLLFNIVRGNITPISTQYSADLRNLINSML
  ||||||| |..| |  .|  | .||||| |||  .|  || | |||| ||. ||||.||  |...|   |   |  |   .|  ||| .|  .| .|.
VVVKLGDFGLARMLNHDTSFAHTFVGTPYYMSPEQMHGQKYNEKSDIWSVGCLIYEMCALHPPFQATNQAQLQEKIKQGHFRRIPYQYSRHLNEIIHFMI

SKDPKLRPTATEIVKKPII
  |.. ||   || . | |
NVDHYHRPSIEEILQHPQI
Kinase 87328.m00164.AA CAMK 9-258 20 5.2e-81 260.65 In-house 1-425 (425) Show / Hide 
Range on Protein: 9-258
Range on HMM: 1-425/425
Sequence Identity: 20% (87 aa)

VLGEGGFAKAFLVKRK-TDR-----------LLCVAKSVKLSGLS--------------------------EKEKKEAISEVNVLSA-------LKHPNI
.||.|.|.| .|...| | .             . .| .. . |.                          .| .|.  .|.....        |.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRYIESFNESGF-------------------LYIIM---EYADGG----DLSQKIEKNGR-------------KSFSEDEVLRIFTQLALAIKYIHDRKI
.. .| .  . .                   .|..|   ||..||    || ..| ..|.             . |.|.|. |.| |.. |..|.|...|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

LHRDLKGQNVFLMKD-----------------GSVKLGDFGIAKVLDH-----------------------TMQFYNTQIGTPYYLS-PEMCQGKN----
 |||||  |. | ..                 . .|. ||| |...|.                       . | ..|. |||.| . ||. .||     
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

----------YNSKTDIWSFGCIMYEMCTLHHAFEGR-------------NINNLLFNIVRGNITPISTQ-----------------------YSADLRN
          |. |.|.|| |.|.| | . .  |.|              |...|. .| .|. . .. .                        |.. ..
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LINSMLSKDPKLRPTATEIVKKPII
||..|| .||. |.|.... . | .
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 87328.m00164.AA Ciliate-E2 4-258 21 5.5e-75 255.43 In-house 1-365 (365) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-365/365
Sequence Identity: 21% (80 aa)

YEQIKVLGEGGFAKAFLVKR-KTDRLL-----------------CVAKSVKLSGLSEKEKKEAISEVNVLSALK----------------HPNIVRYIES
|. ||..|.|.|.. ...|. |....                  . .| . .  ........  .| ...  ..                ||||....|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FN--ESGFLYIIMEYADGGDLSQKIEKN----------GRKSFSEDEVLRIFTQLAL---------------AIKYIHDRK-ILHRDLKGQNVFLMKDGS
|       .|..|||..|||| . |..|          . |.|.| |...|..|..                |..|.| .. |.|||.| .|...     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

VKLGDFGIAK----------------VLDHTM----------------QFYNTQIGTPYYLSPEMCQGKN---------YNSKTDIWSFGCIMYEMCTLH
.|. |||..|                 .                    . .||..|||.|..||. .||.         |. | ||||.|.|.|||..  
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

HAFEGRNINNLLFNIVRGNITP-------------ISTQYSADLRNLINS----MLSKDPKLRPT-ATEIVKKPII
. |    ... . . .. .                .  . | .  .||.     || |||. |.| . .| . |..
PPF----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 87328.m00164.AA ULK 4-258 28 4.9e-73 248.96 In-house 1-329 (329) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-329/329
Sequence Identity: 28% (93 aa)

YEQIKVLGEGGFAKAFLVKRKTDR----LLCVAKSVKLSGLSEKEKKEA--------ISEVNVLSALK--------HPNIVRYIESFNESGF--LYIIME
|. ...||.| |.| .  . | .      ....| . .. ...|..           ..|. ..  ||        |||||.... |..| .  .|||||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YADGGDLSQKIEKNGR--------KSFSEDEVLRIFTQLALAIKYIHDRKILHRDLKGQNVFLMKD------------GSVKLGDFGIAKVLDHT-M--Q
| .||||.| |.||..        | .||.|.. .| |.. . |..|...| |||.| ||. . ..            | .|..||| ||..|   |  |
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

FYNTQI------GTPYYLSPEMCQ----GKNYN-SKTDIWSFGCIMYEMCTLHHAFEGRNINNLLFNIVRGN------------ITPIS-------TQYS
 . |.       |||.| .|.  |    .|.|. .|.||||.|||.||| .    |..  .| .  .|.. .             .|.         | |
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

ADLRNLINSMLSKDPKLRPTATEIVKKPII
 ....||  || .|.| | . .|. . |..
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 87328.m00164.AA Ciliate-E2-Unclassified 4-258 25 2.7e-72 246.47 In-house 1-352 (352) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-352/352
Sequence Identity: 25% (89 aa)

YEQIKVLGEGGFAKAFLVKRKTDRLL------CVAKSVKLSGLSEK----EKKEAISEVN-------------VLSALKHPNIVRYIESFNESGFLYIIM
|. ||..|.|||.| .....| . ..      ......|     .|     ..... . .              |. ..||.||.... |.    .||.|
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYADGGDLSQKIEKNGR---------------KSFSEDEVL-----RIFTQLALAIKYIHDRK-ILHRDLKGQNVFLMKDG---SVKLGDFGIAKVLDHT
||..||||.| |.|..                | |.| ...     ..| |. ....|.|  . |.|||.| .|... ..|    .|. ||||.| ..  
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

---------------MQFYNTQIGTPYYL----SPEMCQGKNYN----SKTDIWSFGCIMYEMCTLHHAFEGRNINN----------------LLFNIVR
                | ..|..|||.|.    .||. ||.||.     | ||||.|.|.|||..  . |...| .                 |. ||  
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

GNITPIS-------TQYSADLRNLIN----SMLSKDPKLRPTATEIVKKPII
.||   .        . |    ..||    .|| |.|. |.|. .| . |..
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 87328.m00164.AA Pkinase_Tyr 4-199 24 1e-27 94.46 Pfam 1-210 (270) Show / Hide 
Range on Protein: 4-199
Range on HMM: 1-210/270
Sequence Identity: 24% (53 aa)

YEQIKVLGEGGFAKAFLVKRK----TDRLLCVAKSVKLSGLSEKE--KKEAISEVNVLSAL-KHPNIVRYIESFN-ESGF--LYIIMEYADGGDLSQKIE
 . .|.|||| | . .. . |     ... .  |..   | ....  ... ..|..... | .||||||..     ...   .||.|||. .|||     
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

KN--GRKSFSEDEVLRIFTQLALAIKYIHDRKILHRDLKGQNVFLMKDGSVKLGDFGIAKVLDHTMQFYNTQIGT-----PYYLSPEMCQGKNYNSKTDI
|.  ......  . | . .| | .  | ..... ||||   |. . ... || .||| |. . .    | .. ..        ..||  . . ...|.|.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKSDV

WSFGCIMYEMCTL
||||  |.|..|.
WSFGVLMWEIFTY
Kinase 87328.m00164.AA TyrKc 4-256 22 4.3e-25 90.62 SMART 1-280 (280) Show / Hide 
Range on Protein: 4-256
Range on HMM: 1-280/280
Sequence Identity: 22% (65 aa)

YEQIKVLGEGGFA---KAFLVKRKTDRLLCVAKSVKLSGLSEKEKKEAISEVNVLSAL--KHPNIVRYIESFNES-------GFLYIIMEYADGGDLSQK
 . .|.|||| |    |. .       . .  |..| .      ... ..| .... |  .|||||| .    ..       . |.|.|||...||| . 
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

IEKNGRKSFSEDEVLRIFTQLALAIKYIHDRKILHRDLKGQNVFLMKDGSVKLGDFGIAKVLDHT------MQFYNTQ--IGTP-----YYLSPEMCQGK
. |...| .. .. | . .| |    |.|.... ||||   |. . ... || .||| .. ...        . | ..   |.        ..||  . .
LRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

NYNSKTDIWSFGCIMYEMCTL-HHAFEG-----RNINNLLFNIVRGNITPISTQ--------YSADLRNLINSMLSKDPKLRPTATEIVKKP
 ...|.|.||||  |.|..|.     .|      .   .. .. .|.  |.            .... ... .    ||. ||| .||... 
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF