Gene 93904.m00250 (T.vaginalis)

93904.m00250

Species: T.vaginalis
Alias: 93904.m00250, TvagK0111
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: AMPK

Sequence

Name Sequence Type Origin Length Description Download
93904.m00250.AA Protein None 439 None Fasta, JSON
93904.m00250.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of 93904.m00250.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 93904.m00250.AA AMPK 9-260 42 9.69999999999e-102 302.81 In-house 1-254 (254) Show / Hide 
Range on Protein: 9-260
Range on HMM: 1-254/254
Sequence Identity: 42% (108 aa)

YELFDKIGEGSFAFVWEGRNTITNCPCAVKQFRKDTFNHEAAV-SMNREISIMQILDHPLIAQLYEVV-ETQHDTFLFMELVDNGTLLEYINKNAPISEN
| . ..||||.|  |  |  ..|.   |.|   |.    .. | .  |||.|.... || | |||||. ||. | |..|| | .| | .|| |.  ..| 
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

KSRIIFAQIVAVLDYLHNEKRVVHRDLKAENILIDQNDNIRVIDFGLSNVLNQNTVLYTACGSSAYVAPEMLLNKPYT-QAADIWSAGVLLYAMNAAHLP
 ..  |.||.. ..|.|. . .|||||| ||.|.|.| || . ||||||. . .  |.|||||  | ||||  .|.|     |||| || ||||  . ||
EACRFFQQIISGVEYCHRHM-IVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLP

FEDSNVTRLVDKVLNRQPEYPLAFSKNLTELISKMLTKDPSQRITLEGILHDPWF
|.|.|.. | .|..| ... |  .|..  .||..||..|| .||| . |  .|||
FDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 93904.m00250.AA CAMKL 9-260 34 1.5e-99 318.41 In-house 1-297 (297) Show / Hide 
Range on Protein: 9-260
Range on HMM: 1-297/297
Sequence Identity: 34% (102 aa)

YELFDKIGEGSFAFVWEGRN-TITNCPCAVKQFRKDTFNHEAAVSMN-------------REISIMQILD---HPLIAQLYEVVETQHD------TFLFM
|.. . .|.|||. |  ...  .|..  |.|   |.  . .  ...|             |||.||. |.   || | .||||.||.         .|.|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELVDNGT--LLEYINKN----APISENKSRIIFAQIVAVLDYLHNEKRVVHRDLKAENILIDQND--NIRVIDFGLSNVLN-Q----NTVLYTACGSSAY
|....|   |..|| |.     ...|.  | .| |||. ..|.|. . .||||.|.||||.|.|.  || .||||.||    .    .  | | ||| .|
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHG-IVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

VAPEMLLN--KPYT-QAADIWSAGVLLYAMNAAHLPFEDS--------NVTRLVDKVLNRQPEYPLAFSK-NLTELISKMLTKDPSQRITLEGILHDPWF
 |||...   |||  ...||||.||.||||   .|||.|         |. .|  |.     ..|  ..   .  ||.|||...|..|.|.. |. .||.
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 93904.m00250.AA CAMK 14-260 22 4.3e-96 310.11 In-house 1-425 (425) Show / Hide 
Range on Protein: 14-260
Range on HMM: 1-425/425
Sequence Identity: 22% (95 aa)

KIGEGSFAFVWEGRNTITN------------CPCAVKQFRKDTFN--------------------------HEAAVSMNREISIMQI-------LDHPLI
..|.|||. | ..... |.              .|.|   |.                              .   .. |||.||.        |||| |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

AQLYEVVE------------TQHD--------TFLFM---ELVDNG----TLLEYINKNAP---------------ISENKSRIIFAQIVAVLDYLHNEK
 .|||| |            |  .         ...|   |....|     |..|| .. .               ..|   | .| ||.  ..|.|. .
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

RVVHRDLKAENILIDQND-----------------NIRVIDFGLSNVLNQ------------------------NTVLYTACGSSAYVA-PEMLLN----
 .|||||| ||||.|.|.                 || .||||..|....                        .  ..| ||. .|.| ||.|.     
-IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

----------KPYTQAADIWSAGVLLYAMNAAHLPFEDS-------------NVTRLVDKVLNRQPE-YPLAFSK-----------------------NL
          ..|....|.||.||.||.|   ..||...             |  .|  |... . . .|  ||.                         
NMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQEC

TELISKMLTKDPSQRITLEGILHDPWF
  ||.|||..||..|.|.| .| .||.
KDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 93904.m00250.AA S_TKc 9-260 31 4e-88 299.98 SMART 1-231 (231) Show / Hide 
Range on Protein: 9-260
Range on HMM: 1-231/231
Sequence Identity: 31% (85 aa)

YELFDKIGEGSFAFVWEGRNTITNCPCAVKQFRKDTFNHEAAVSMNREISIMQILDHPLIAQLYEVVETQHDTFLFMELVDN--GTLLEYINKNAP----
||. .|||.|.|. |. .|.. |.  .|.|. .          .. |||.|..  .|| | .||.| .. .. ...||..|.  |.|..|| |. .    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--ISENKSRIIFAQIVAVLDYLHNEKRVVHRDLKAENILIDQNDNIRVIDFGLSNVLNQNTVLYTACGSSAYVAPEMLLNKPYTQ-AADIWSAGVLLYAM
  ..|   | ...||.  |.|.|.  ...||||| ||||.|.  .| ..||||. .|      .| ||.  |.|||.|   .|.  ..|.|| |..|| |
FPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

NAAHLPFEDSNVTRLVDKVLNRQPEYPLAFSKNLTELISKMLTKDPSQRITLEGILH-------DPWF
 .   ||.  .. .. .|..          |. . ..|.|.|.|||..|.|   .|.       .|||
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 93904.m00250.AA Pkinase 9-260 29 2.1e-82 284.88 Pfam 1-293 (293) Show / Hide 
Range on Protein: 9-260
Range on HMM: 1-293/293
Sequence Identity: 29% (86 aa)

YELFDKIGEGSFAFVWEGRNTITNCPCAVKQFRKDTFNHEAAVSMNR--EISIMQILDHPLIAQLYEVVETQHDTFLFMELVDNG----TLLEYIN--KN
|..  |||.|||. |.....  |..  |||...|.. ...  ..  |  ||.||. |.|| | .||...|.  .  . ||....|     | .||   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

API--SENKSRIIFAQIVAVLDYLHNEKRVVHRDLKAENILIDQNDNI----RVIDFGLSNV--LNQNTVLYTACGSSAYVAPEMLL-NKPYTQAADIWS
 ..  ||.  . .. ||.  |.|.|. ....||||| ||||||.|..|    ...||||. .  .  |. ..| ||.. |.||| .. ...|....|.||
GCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

AGVLLYAMNAAHLPFEDS------NVTRLVDKVLNRQPEYPLAFS---------------------KNLTELISKMLTKDPSQRITLEGILHDPWF
.|..|| |   ..|| ..      .   ...... ......   .                     ... ..|...|.|||..|.| | ||..|||
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 93904.m00250.AA MARK 9-260 38 2.4e-81 265.68 In-house 1-262 (262) Show / Hide 
Range on Protein: 9-260
Range on HMM: 1-262/262
Sequence Identity: 38% (101 aa)

YELFDKIGEGSFAFVWEGRNTITNCPCAVKQFRKDTFNH-EAAVSMNREISIMQILDHPLIAQLYEVVE--TQHD-TFLFMELVDNGTLLEYINKN--AP
|..   ||.||.| |  .... |.   |.|   |   |  ..  .  |||.||. |||| | .|..|.|  |    ..| ||.. .| |..|| .    .
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

ISENKSRIIFAQIVAVLDYLHNEKRVVHRDLKAENILIDQND--NIRVIDFGLSNVLNQNTVLYTACGSSAYVAPEMLLNKPYT-QAADIWSAGVLLYAM
..|.  | || |||  . |.|.   .||||.|.||||||.|   ||  ||||.|.  . .. | | ||. .| |||..| |||. ...|||| ||.||.|
LHEEEARRIFRQIVSAVNYCHSKN-IVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFM

NAAHLPFEDSN--VTRLVDKVLNRQPEYPLAFSKNLTELISKMLTKDPSQRITLEGILHDPWF
   ..||....     |  |.|. ....|   || .  ||...|| .|..|.|.| |. .||.
VCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 93904.m00250.AA QIK 9-260 36 7.9e-72 244.95 In-house 1-272 (272) Show / Hide 
Range on Protein: 9-260
Range on HMM: 1-272/272
Sequence Identity: 36% (99 aa)

YELFDKIGEGSFAFVWEGRNTITNCPCAVKQFRKDTFNHEAAVSMNREISIMQILDHPLIAQLYEVVETQHDTFLFMELVDNGTLLEYINKNAP------
|..   || | || |  .|. ||    |.|   |   . |    . ||. ||  |.|| |  ||.| ||.   .. .|   || . .|..|.        
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKMV

--------------ISENKSRIIFAQIVAVLDYLHNEKRVVHRDLKAENILIDQNDNIRVIDFGLSNVLNQNTVLYTACGSSAYVAPEMLLNKPYT-QAA
              ..||. | .| ||..  .|.| .. .|||||||||||.|.| || ..|||.||   |   | | ||| .| ||||.. | |.   .
NSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCH-KRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKV

DIWSAGVLLYAMNAAHLPFEDSNVTRLVDKVLNRQPEYPLAFSKNLTELISKMLTKDPSQRITLEGILHDPWF
|||| ||.||.. .  |||  .... | ..||  .   |   |. . .|| .||. ||..|.| . |.  .| 
DIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase 93904.m00250.AA ULK 9-260 26 1.7e-71 243.87 In-house 1-329 (329) Show / Hide 
Range on Protein: 9-260
Range on HMM: 1-329/329
Sequence Identity: 26% (87 aa)

YELFDKIGEGSFAFVWEGRNTIT----NCPCAVKQFRKDTFNHEAAV--------SMNREISIMQILD--------HPLIAQLYEVVETQHD--TFLFME
|.| ...|.|||. | .||| .|    |  .|.|.  |...| .           . ..|| ||. |.        || | .||.. ||...  ....||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LVDNGTLLEYINKNAP----------ISENKSRIIFAQIVAVLDYLHNEKRVVHRDLKAENILIDQNDN------------IRVIDFGLSNVLNQNT---
. . |.| .||.|| .          .||.. ...| ||.. . .|| .....|||.| .||||. ..             . . |||.. ... ..   
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELH-KHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQ

-VLYTAC------GSSAYVAPEMLL----NKPYT-QAADIWSAGVLLYAMNAAHLP----FEDSN---VTRLVDK-------VLNRQPEYPLA-----FS
 ...|.       |.  | ||. |     .|||.   .|||| |...| |     |    |.| .   ...|...       . ......| .     .|
QMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

KNLTELISKMLTKDPSQRITLEGILHDPWF
... .||..||..|...||. | ... |||
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 93904.m00250.AA ULK 9-260 27 9.3e-71 241.38 In-house 1-324 (324) Show / Hide 
Range on Protein: 9-260
Range on HMM: 1-324/324
Sequence Identity: 27% (90 aa)

YELFDKIGEGSFA-FVWEGRNTIT---NCPCAVKQFRKDTFNHEAAV--------SMNREISIMQILD---HPL--IAQLYEVVETQHD--TFLFMELVD
|.| ...|.|||.  | .||| .|   |   |.|.  |. .|             . ..||.||..|.   ||   | .||.. ||...  ....||. .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

NGTLLEYINKNAP---------ISENKSRIIFAQIVAVLDYLHNEKRVVHRDLKAENILIDQNDN------------IRVIDFGLSNVLNQN----TVLY
 |.| .||.|| .         .||.. ...| ||.. . .|| .. ..|||.| .||||  ..             . . |||.. ... |    ....
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELH-KHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

TAC------GSSAYVAPEMLL----NKPYT-QAADIWSAGVLLYAMNAAHLP----FEDSN--VTRLVDK-------VLNRQPEYPL-----AFSKNLTE
|..      |.  | ||. |     .|||.   .|||| |...| |     |    |.| .  . .|...       . |.. ..|.      .|... .
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

LISKMLTKDPSQRITLEGILHDPWF
||..||..|...||. | |.. |||
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase 93904.m00250.AA Ciliate-E2 9-260 23 7e-70 238.48 In-house 1-365 (365) Show / Hide 
Range on Protein: 9-260
Range on HMM: 1-365/365
Sequence Identity: 23% (90 aa)

YELFDKIGEGSFAFVWEGRNTITNC------------------PCAVKQFRKDTFNHEAAVSMNREISIMQ----------------ILDHPLIAQLYEV
|..  |||.|.|. |.....  ...                   ...|.. . ....    ....||.||.                .|.|| | ..||.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

VE--TQHDTFLFMELVDNGTLLEYINKN-----------APISENKSRIIFAQIVA---------------VLDYLHNEKRVVHRDLKAENILIDQNDNI
 .  ...  .| ||... |.|..||..|            ...|.. . |..||.                 | |||......|||.| ||||.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

RVIDFGLS-NVLNQNT-------------------------------VLYTACGSSAYVAPEMLLNKP---------YTQAADIWSAGVLLYAMNAAHLP
 .|||||| .. ..|                                . .| ||.  |.|||.| .|.         |. ..||||.||.|| |    .|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FEDSNVTRLVDKVLNRQPEYPLA------------------FSKNLTELISK----MLTKDPSQRIT-LEGILHDPWF
|         .. .. . ..| .                   |..   ||.|    || |||..|||  | ||  |||
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 93904.m00250.AA Ciliate-E2-Unclassified 9-260 24 1.4e-64 220.82 In-house 1-352 (352) Show / Hide 
Range on Protein: 9-260
Range on HMM: 1-352/352
Sequence Identity: 24% (85 aa)

YELFDKIGEGSFAFVWEGRNTITNCP------CAVKQFRKDTFNHEAAVSMNREISIMQI------------------LDHPLIAQLYEVVETQHDTFLF
|..  .||.|.|. |.. ..  ..        . .... .   ...    || .. ....                  ..||.|  .... ...   .. 
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MELVDNGTLLEYINKNAP-----------------ISENKSR-----IIFAQIVAVLDYLHNEKRVVHRDLKAENILIDQND---NIRVIDFGLSNVLNQ
||....|.|..||.|.                   ..|....      .||||.  |.||| .. ..|||.| ||||.|.|    .|..||||.|  ..|
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

N----------------TVLYTACGSSAYV----APEMLLNKPYT----QAADIWSAGVLLYAMNAAHLPFEDSNVTR----------------LVDKVL
|                  ..| ||.  |     |||.| .. |      ..|||| ||.||.|    .||.| | .                 | .. .
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

NRQPEYPL--------AFSKNLTELIS----KMLTKDPSQRITLEGILHDPWF
......|           |..  ..|.    ||| |.|..|||.| ||  |||
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 93904.m00250.AA TSSK 55-260 36 4.5e-64 209.18 In-house 64-289 (289) Show / Hide 
Range on Protein: 55-260
Range on HMM: 64-289/289
Sequence Identity: 36% (82 aa)

REISIMQI-LDHPLIAQLYEVVETQH-DTFLFMELVDNGTLLEYINKN------APISENKSRIIFAQIVAVLDYLHNEKRVVHRDLKAENILIDQNDNI
|||.|| . |.|| | |.||  ||..   ...||. ..|.|||||...       ...| ..|  | |.|. ..|.|. . ||||||| |||| | . ||
REIQIMRKTLKHPNIIQFYEMFETCQGKIYMVMEYAEHGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHS-HNVVHRDLKCENILLDKHWNI

RVIDFGLSNVLNQNT------VLYTACGSSAYVAPEMLLNKPY-TQAADIWSAGVLLYAMNAAHLPFED--SNVTRLVDKVLNRQPEYP----LAFSKNL
  .||| ....  .        . | ||| ||.||| |. .||   ..|.|| || ||.|  ...|| |  ||.... . . .. . .|    .. |.  
KLTDFGFARYWPRDDPGRCCHLSKTFCGSYAYAAPEILRGIPYDPKWYDVWSMGVILYIMVCGCMPFDDDKSNIHKMLWQQQEHKVCFPKPHSCWISQEC

TELISKMLTKDPSQRITLEGILHDPWF
  ||..||. .|..|.... |.|..| 
KDLIRHMLQPHPCNRPHINEICHHCWM
Kinase 93904.m00250.AA Pkinase_Tyr 9-197 29 1.9e-19 66.5 Pfam 1-205 (270) Show / Hide 
Range on Protein: 9-197
Range on HMM: 1-205/270
Sequence Identity: 29% (63 aa)

YELFDKIGEGSFAFVWEGRNT----ITNCPCAVKQFRKDTFNHEA--AVSMNREISIMQIL-DHPLIAQLYEVVE-TQHD--TFLFMELVDNGTLLEYIN
 ..  |.|||.|  |..|. .     |..|.|||   |..  ||.    .. ||..||  | .|| | .|| |.   .     .. ||.. .| ||.|  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

KNAPISENKSRIIFAQIVAV-------LDYLHNEKRVVHRDLKAENILIDQNDNIRVIDFGLSNVLNQNTVLY-TACG----SSAYVAPEMLLNKPYTQA
|.    |.| ..   ...         ..||. .|. .|||| | |.|.. |  ... ||||.  . .|.  | .. |         ||| . .. .| .
KHR---EDKQPLTMKDLLQMCWQIAKGMEYLE-SKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYGKFTTK

ADIWSAGVLLY
 |.|| |||..
SDVWSFGVLMW
Kinase 93904.m00250.AA TyrKc 9-255 23 7.4e-17 49.81 SMART 1-280 (280) Show / Hide 
Range on Protein: 9-255
Range on HMM: 1-280/280
Sequence Identity: 23% (69 aa)

YELFDKIGEGSFAFVWEGRNTITNCPCAVKQFRKDTFNHEAAVSMNREISIMQIL--DHPLIAQLYEVVETQ-------HDTFLFMELVDNGTLLEYINK
 .| .|.||| |  |..|. .    ..|||  ..|.        . ||..||  |  .|| | .|| |. .|       .  .. ||....| |..|. |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

NAP-ISENKSRIIFAQIVAVLDYLHNEKRVVHRDLKAENILIDQNDNIRVIDFGLSNVLNQN------TVLYTA----CGSS----AYVAPEMLLNKPYT
. | ..  .   .  || .  .||| .|...|||| | |.|.. |  ... |||||  .         .  |..    .| .       ||| .  . .|
HRPKLCMKDLLSFCWQIACGMEYLH-SKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

QAADIWSAGVLLY-AMNAAHLPFED-----SNVTRLVDKVLNR----QPEY--PLA----FSKNLTELISKMLTKDPSQR---ITLEGIL
 . |.|| ||...  .     | ..      . .... .| ..    ||..  |       .. . .....    ||..|    ..  ..
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYP-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 93904.m00250.AA TSSK 9-38 23 0.00291 6.54 In-house 1-46 (289) Show / Hide 
Range on Protein: 9-38
Range on HMM: 1-46/289
Sequence Identity: 23% (11 aa)

YELFDKIGEGSFAFVWEGRNTITNCP----------------CAVK
|..  |||.||.| | ... . ..|                 .|.|
YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIK