Gene 84626.m00053 (T.vaginalis)
84626.m00053
Species: T.vaginalis
Alias: TvagK0380, 84626.m00053
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| 84626.m00053.AA | Protein | None | 417 | None | Fasta, JSON |
| 84626.m00053.kin_dom | Protein Kinase Domain | None | 254 | None | Fasta, JSON |
Protein domains of 84626.m00053.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| PH | 84626.m00053.AA | PH | 1-95 | 25 | 5.9e-07 | 30.36 | SMART | 3-82 (82) | Show / Hide |
Range on Protein: 1-95 Range on HMM: 3-82/82 Sequence Identity: 25% (24 aa) MEGWLVKRSGIPHFWHKRYCVIESNCFYIYLDQQRQKMTNWFSITPKSQVALMESKKGLRFKITQPEGKDFAFQAKDEKEFHAWLNHILLLSIPE .|||| |.| |.||..|. ..|.|.| | | .... .| . |.|. .. . ||...|.|.. |...| .. . KEGWLYKKS--K-RWKKRWFVLFNDCLYYYKDK---KPKGSIPLSDC-TVRE-P-----CFEIHH-DR-TYYFQCESEEEMQEWMQAIQKAIHNN |
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| PH | 84626.m00053.AA | PH | 1-93 | 25 | 1e-06 | 26.5 | Pfam | 3-92 (92) | Show / Hide |
Range on Protein: 1-93 Range on HMM: 3-92/92 Sequence Identity: 25% (24 aa) MEGWLVKRSGIPHFWHKRYCVIESNCFYIYLDQQRQKMTNWFSITPKSQVALMESKKGLRFKITQPEGKDFAFQAKDEKEFHAWLNHILLLSI .|||| |.. |.||..|. .|| |.| | . . ... . . . ..|. |.|. ... . |||..|.|.. |...| .. KEGWLHKKG-KRKSWKKRWFVLFNNCLYYYKDDK-YRPKGSIPLSDCQVTKVPDNKRPHCFQIRT-DRRTYYFQAESEEEMNDWMQAIQSACR |
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| Kinase | 84626.m00053.AA | AGC | 103-356 | 30 | 1.4e-148 | 387.13 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 103-356 Range on HMM: 1-395/395 Sequence Identity: 30% (121 aa) YEIISVLGRGFYGKVVLAKHK------KTGKFCAIKSIHKKV-LLDMK--KVDTIMVE------------RDILKSTK----------SPFIVS-LLSSF .|.. |.|.| .||| |...| |||..|.| . ||. ...| .|. .|.| |.||. . .||||. | .|| FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF QTPSK--FYLVLEYVS---------GG-DLFMHLTN--NNNEISVDQIKLYIAE-------LAVALEQLHK-DHIIYRD-LKPENVLICEDGHIKLTDFG |.... |.|.||.. || .||.|| . .. . .... |.|| .. ||| ||. .||.|| |||||.|. ||||||||||| QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG ISKMLN--------------------------------------------------EKQSTTNTLCG--TGEYLAPEVISDKGYTEAIDWWQ--LGILMY .|... .|. .|.|.|| | ||.|||.. |. | ||| ||.||| LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY EMVVGKTPFADTN----------KSIMYSNIMN-----KNPNFFPIE-----------DENARNLIAHLLRKDPAKRAG----------FEEIKNSKFF ||..|..|| . | . |. .||| ... || ...|..|| .|| |||.|| | .||||| ..| EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF |
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| Kinase | 84626.m00053.AA | SGK | 103-356 | 41 | 9.5e-111 | 343.32 | In-house | 1-283 (283) | Show / Hide |
Range on Protein: 103-356 Range on HMM: 1-283/283 Sequence Identity: 41% (118 aa) YEIISVLGRGFYGKVVLAKHKKT------------------GKFCAIKSIHKKVLL-------DMKKVDTIMVER-DILKSTKSPFIVSLLSSFQTPSKF ....|.| | .||| ..|||.. .|| |.| . |. . |.. || || .||| |.||||.| .|||. | FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL YLVLEYVSGGDLFMHLTNNNNEISVDQIKLYIAELAVALEQLHKDHIIYRDLKPENVLICEDGHIKLTDFGISKMLNEKQSTTNTLCGTGEYLAPEVISD |.|..|| ||..| || . . . |. . | ||.. ||| ||. ||||||||||.| .||..||||| .| ... || | ||| |||||||. YFVMDYVNGGEMFYHL-QREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRK KGYTEAIDWWQLGILMYEMVVGKTPFADTNKSIMYSNIMNKNPNFFPIEDENARNLIAHLLRKDPAKR----AGFEEIKNSKFF ... . ||| ||...||| .|. || . ||..|| ||.|. .. | |. || || ||| || ..|.|||| || QPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF |
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| Kinase | 84626.m00053.AA | Akt | 103-356 | 42 | 2.2e-108 | 347.59 | In-house | 1-264 (264) | Show / Hide |
Range on Protein: 103-356 Range on HMM: 1-264/264 Sequence Identity: 42% (113 aa) YEIISVLGRGFYGKVVLAKHKKTGKFC-AIKSIHKKVLLDMKKVDTIMVERDILKSTKSPFIVSLLSSFQTPSKFYLVLEYVSGGDLFMHLTNNNNEISV ... |||.| .|||.|.| |.|.|. |.|.. |........| .. || ||. ...||||.| ||||. | |.|..|..||.|| || . .| FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHL-QRKRRFSE DQIKLYIAELAVALEQLHKDHIIYRD-LKPENVLICEDGHIKLTDFGISKML-NEKQSTTNTLCGTGEYLAPEVISDKGYTEAIDWWQ-LGILMYEMVVG |... |.||. |.| ||. ||||| |||||.|. .||||.||||| .|. . .|.|.||| ||||||.....|.| | ||| ||..|||| | DRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCG KTPFADTNKSIMYSNIMNKNPNFF--PIEDENARNLIAHLLRKDPAKRAG-----FEEIKNSKFF || . .. |. .|.|.. .| . . ....|| || ||| || | .|||. .| RPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF |
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| Kinase | 84626.m00053.AA | AktR | 103-356 | 39 | 6.3e-100 | 338.29 | In-house | 1-268 (268) | Show / Hide |
Range on Protein: 103-356 Range on HMM: 1-268/268 Sequence Identity: 39% (106 aa) YEIISVLGRGFYGKVVLAKHK-KTGKFCAIKSIHKKVLLDMKKVDTIMVERDILK-STKSPFIVSLLSSFQTPSKFYLVLEYVSGGDLFMHLTNNNNEIS .... .||.| .|||.|...| ...|. |.|.|.|| . . .. . . ||.|.. . |||| | .||| .| ....||. ||.|| || .... .| FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHL-KKKKKFS VDQIKLYIAELAVALEQLHKD-HIIYRDLKPENVLICEDGHIKLTDFGISK--MLNEKQSTTNTLCGTGEYLAPEVISD-KGYTEAIDWWQLGILMYEMV .|.. |.|. ||| ||. .|||||||||| |. ||||.|.|||| || ... .....||| ||.|||.| ||.. ..|||..||. |||| EEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMV VGKTPFADTNKSIMYSNIMNKNPNFFPIED----ENARNLIA-HLLRKDPAKRAG-----FEEIKNSKFF .| .|| . |. .|. .| .|. .... . .....|| || |.| || | .||||. ..| TGCPPFYHKNQNQMFQKIKIKQ-QNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF |
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| Kinase | 84626.m00053.AA | S_TKc | 103-356 | 34 | 3.3e-98 | 333.49 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 103-356 Range on HMM: 1-231/231 Sequence Identity: 34% (93 aa) YEIISVLGRGFYGKVVLAKHKKTGKFCAIKSIHKKVLLDMKKVDTIMVERDILKSTKSPFIVSLLSSFQTPSKFYLVLEYVSG--GDLFMHLTNNNNE-- |||. ..|.| .||| ...|||||. .||| |. ..|. |..|||. . |.|| |. .||. ...|.|.||..| |||| .. ... . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ---ISVDQIKLYIAELAVALEQLHKDHIIYRDLKPENVLICEDGHIKLTDFGISKMLNEKQSTTNTLCGTGEYLAPEVISDKGYTE-AIDWWQLGILMYE .. ... |..... ||| .|. .||.|||||||.|..| |||..|||... | .|.||| .|.||||. ||. ..||| .|...|| RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE MVVGKTPFADTNKSIMYSNIMNKNPNFFPIEDENARNLIAHLLRKDPAKRAGFEEIKN-------SKFF |..|..|| . |. .|. .. |...| ..|.|||.|| . |. . .| MLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | 84626.m00053.AA | PKA | 103-356 | 42 | 1.2e-97 | 330.77 | In-house | 1-263 (263) | Show / Hide |
Range on Protein: 103-356 Range on HMM: 1-263/263 Sequence Identity: 42% (114 aa) YEIISVLGRGFYGKVVLAKHKKTGKFCAIKSIHKKVLLDMKKVDTIMVERDILKSTKSPFIV-SLLSSFQTPSKFYLVLEYVSGGDLFMHLTNNNNEISV .||| .||.| .|.| |..||..|...|.| . | ..| |. .. |. ||...|.|||| .. ..||.... |.|.|||.||..| .| .. | FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYL-RKSGRFSN DQIKLYIA-ELAVALEQLHKDHIIYRDLKPENVLICEDGHIKLTDFGISKMLNEKQSTTNTLCGTGEYLAPEVISDK-GYTEAIDWWQLGILMYEMVVGK .. |.|.| . ||| ||. .|||||||||| || ..||||.|||| .| . . | ||||| ||||||.|. | |. ..||| |||| |||..|. PHAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD---RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGY TPFADT--NKSIMYSNIMNKNPNFFPIEDENA---RNLIAHLLRKDPAKRA-----GFEEIKNSKFF .|| |. .. .| | | .| . | .| . || .|| .|. || | . ||| |.| PPFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF |
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| Kinase | 84626.m00053.AA | MAST | 103-356 | 32 | 8e-92 | 296.27 | In-house | 1-334 (334) | Show / Hide |
Range on Protein: 103-356
Range on HMM: 1-334/334
Sequence Identity: 32% (110 aa)
YEIISVLGRGFYGKVVLAKHKKTGKFCAIKSIHKKVLLDMKKVDTIMVERDILKSTKSPFIVSLLSSFQTPSKFYLVLEYVSGGDLFMHLTNNNNEISVD
.|.| ....| |||| |.|||||... |.| | | ... . ||. .|||.||. ...||.|.. .|||| .. ..|.||..|||.. .| . . ..
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYG-YFDEW
QIKLYIAELAVALEQLHKDHIIYRDLKPENVLICEDGHIKLTDFGISKM-----------L------------------NEKQSTT--------------
|.||||.. .|| ||. |. |||||.|.|| .||||||||| ||. . .. ....
MAKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDDLNMMYEGYTPPNIFNNSTDPMNKNQQDYSQFPGDFGINGNTNKNQI
----------------------NTLCGTGEYLAPEVISDKG-YTEAIDWWQLGILMYEMVVGKTPFADTNKSIMYSNIMNKN---PNFFPIEDEN-----
. .||| .|.||||| ..| . ..||| .|| ||| || .|| | . . ..|| |.| . . .| |
QQQQEQPQCQQQNMRPHNIHQNKQCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAM
---ARNLIAHLLRKDPAKRAGFE----EIKNSKFF
|. || || || || |. |.|. .||
SPEAQDLIEKLLQPDPRKRLGANNGADEVKQHPFF
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| Kinase | 84626.m00053.AA | RSK | 106-356 | 38 | 1.3e-91 | 310.71 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 106-356 Range on HMM: 1-278/278 Sequence Identity: 38% (108 aa) ISVLGRGFYGKVVLAKHK---KTGKFCAIKSIHKKVLLDMKK-VDTIMVERDILKSTK-SPFIVSLLSSFQTPSKFYLVLEYVSGGDLFMHLTNNNNE-- ..|||.| |||| | . . .||. | | ..|... .| . . | ||.||. .. .||||.| .|||..|.||..||..||.||.|| . LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC ISVDQIKLYIAELAVALEQLHKDHIIYRDLKPENVLICE---DGHIKLTDFGISKM-LNEKQSTTNTLCGTGEYLAPEVIS----DKGYTEAIDWWQLGI .| | . |.||...|.| ||. .||.|||||||.| . .||||||||| .| ... . |.| |.| ||.|||.. ..|...| ||| ||. FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV LMYEMVVGKTPFAD---TNKSIMYSNIMNKN--PNFF--PIEDENARNLIAHLLRKDPAKRAG-----FEEIKNSKFF ||||| .|..||. |.. .|.... ... . ..|..|| ..| .||.|| | ||||....| LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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| Kinase | 84626.m00053.AA | Pkinase | 103-356 | 32 | 1.7e-85 | 295.13 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 103-356 Range on HMM: 1-293/293 Sequence Identity: 32% (95 aa) YEIISVLGRGFYGKVVLAKHKKTGKFCAIKSIHKKVLLDMKKVDTIMV--ERDILKSTKSPFIVSLLSSFQTPSKFYLVLEYVSGG----DLFMHLT-NN |.|....|.| .|.| ...||.||| |.| | |. ...| | | |.|. ..|.|| |. .|..... |.|.||. || ||| ... . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR NNEI--SVDQIKLYIAELAVALEQLHKDHIIYRDLKPENVLICEDGHI----KLTDFGISKML-NEKQSTTNTLCGTGEYLAPEVIS-DKGYTEAIDWWQ .. . | ...| |. ... .|| .|. ||.|||||||.|| ..||| |..|||..| . . ..| ..|.||| .|.||||| ...|. ..|.| HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS LGILMYEMVVGKTPFADT------NKSIMYSNIMNKNPNFFPIED---------------------ENARNLIAHLLRKDPAKRAGFEEIKNSKFF .|...|||. |..|| . .. |. .|| . . | .. |... .| .|.|||.|| ..|.|.....| CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | 84626.m00053.AA | Ciliate-E2-Unclassified | 103-356 | 28 | 1.4e-84 | 287.26 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 103-356
Range on HMM: 1-352/352
Sequence Identity: 28% (102 aa)
YEIISVLGRGFYGKVVLAKHKKTGKFC-----AIKSIHKKVLLDMKKVDTIMVERDILKSTK-------------------SPFIVSLLSSFQTPSKFYL
|.|| ..|.| .||| ...|||.. . ..|....|... |.| || | ..... | .|||| .. ||. ..|.
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI
VLEYVSGGDLFMHLTNNNN----------------EISVDQIK-----LYIAELAVALEQLHKDH-IIYRDLKPENVLICEDG---HIKLTDFGISK---
|.||. ||||. ....... ... |.| |.|.. ..||.||. . ||.||.||||.|. ..| .||..||||||
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ
------------MLNEKQSTTNTLCGTGEYL----APEVISDKGYT----EAIDWWQLGILMYEMVVGKTPFADTNKSI----------------MYSNI
| . || ..| ||| .|. ||||. ..| ...|.| ||...|||. |. || |.|. . .|.||
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI
MNKNPNFFPIE--------DENARNLIA----HLLRKDPAKRAGFEEIKNSKFF
..||..|.. . ...| ..| .| |.| || .||.|.| .|
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
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| Kinase | 84626.m00053.AA | Ciliate-E2 | 103-356 | 25 | 2.8e-82 | 279.66 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 103-356 Range on HMM: 1-365/365 Sequence Identity: 25% (97 aa) YEIISVLGRGFYGKVVLAKHKKTG-----------------------KFCAIKSIHKKVLLDMKKVDTIM----------VERDILKSTKSPFIVSLLSS |..| ..|.| .|.| ..|..|.. |. |.|...|. . .|... || |. ||.. ..|.|. . . YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC FQ--TPSKFYLVLEYVSGGDLFMHLTNN----NNE------ISVDQIKLYIAELAV---------------ALEQLHKDH-IIYRDLKPENVLICEDGHI || . ...|||.||..||||| .. || |.| .. .|| ...... ||| ||. . ||.||.||||.|. | FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I KLTDFGISKMLNEK-------------------------------QSTTNTLCGTGEYLAPEVISDKG---------YTEAIDWWQLGILMYEMVVGKTP |..|||.|| .... | ..||.||| .|.|||... |. |....|.| ||...|||. ||.| KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP FADTNKSIMYSNIMNKNPNFFPIE------------------DENARNLIAH----LLRKDPAKRAG-FEEIKNSKFF | . .|.... .|.. | .... .|| .| ||| || . .|.|.| ..| F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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| Kinase | 84626.m00053.AA | MAST | 103-256 | 43 | 1e-66 | 202.59 | In-house | 1-157 (337) | Show / Hide |
Range on Protein: 103-256 Range on HMM: 1-157/337 Sequence Identity: 43% (68 aa) YEIISVLGRGFYGKVVLAKHKKTGKFCAIKSIHKKVLLDMKKVDTIMVERDILKSTKSPFIVSLLSSFQT--PSKFYLVLEYVSGGDLFMHLTNNNNEIS .|.| ....| ||.| |.|||||... |.|.| . ..| . ||...|||.||. .. ||.|.. .|||| . ..|.||..||| . .| . .| FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP VDQIKLYIAELAVALEQLHKDHIIYRDLKPENVLICEDGHIKLTDFGISKM-LNEKQ .. |.||||. .|| ||. |. |||||.|.|| .||||||||| ||. .. |. EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDKT |
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| Kinase | 84626.m00053.AA | MAST | 263-356 | 38 | 4e-30 | 88.72 | In-house | 229-337 (337) | Show / Hide |
Range on Protein: 263-356 Range on HMM: 229-337/337 Sequence Identity: 38% (42 aa) CGTGEYLAPEVISDKG-YTEAIDWWQLGILMYEMVVGKTPFADTNKS-IMYSNIMN--KNPNFFPIEDEN--------ARNLIAHLLRKDPAKRAGFE-- ||| .|.||||| .| | ..||| .|| ||| || .|| . . . .|| | .. .. ...| | |. || ||...| || |. CGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLGANGA -EIKNSKFF |||. .|| DEIKQHPFF |
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| Kinase | 84626.m00053.AA | TyrKc | 103-356 | 20 | 5.3e-17 | 52.18 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 103-356 Range on HMM: 1-280/280 Sequence Identity: 20% (59 aa) YEIISVLGRGFYGKVVLAKHKKTGKFCAIKSIHKKVLLDMKKVDTIMVERDILKST--KSPFIVSLLSSFQTP-------SKFYLVLEYVSGGDLFMHLT . . .||.|..|.|.... | .|.|.... . .| | |... . | || |. .. ..|.||...||| .| ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR NNNNEISVDQIKLYIAELAVALEQLHKDHIIYRDLKPENVLICEDGHIKLTDFGISKMLNEK-------QSTTNTLCGTGE------YLAPEVISDKGYT .. ....... . | | ||. ..| ||| |.|. |....| .||| |. . .. . . . . | .|||.| .. .| KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT EAIDWWQLGILMYEMV-VGKTPFAD-----TNKSIMYSNIMNKNPNFFPIE---------DENARNLIAHLLRKDPAKRAGFEEIKNSKFF .. | | |..|.|. |..| . . . .. .... . | . . ... . ||..| |.|| ..| TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF |
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| Kinase | 84626.m00053.AA | Pkinase_Tyr | 103-304 | 24 | 1.5e-13 | 46.47 | Pfam | 1-218 (270) | Show / Hide |
Range on Protein: 103-304 Range on HMM: 1-218/270 Sequence Identity: 24% (55 aa) YEIISVLGRGFYGKVVLAKHK----KTGKFCAIKSIHKKVLLDMKK---VDTIMVERDILKST-KSPFIVSLLSSFQ-TPSK--FYLVLEYVSGGDLFMH ... .||.| .|.|.... | .|. .|.|.. | |.. . | | |.|. . | ||.|. |.|.||. .||| . ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE--GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY LTNN---NNEISVDQIKLYIAELAVALEQLHKDHIIYRDLKPENVLICEDGHIKLTDFGISKMLNEKQSTT-NTLCGTGE---YLAPEVISDKGYTEAID | .. .. ... .. . .. | ..| |. ..| ||| |.|. |....| .||| .. . .. .. . |. .|||.|... .|.. | LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSD WWQLGILMYEMVV-GKTP-FAD | |.||.|.. |..| ... VWSFGVLMWEIFTYGEQPTYPG |
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