Gene 80273.m00037 (T.vaginalis)

80273.m00037

Species: T.vaginalis
Alias: TvagK0938, 80273.m00037
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMK1

Sequence

Name Sequence Type Origin Length Description Download
80273.m00037.AA Protein None 314 None Fasta, JSON
80273.m00037.kin_dom Protein Kinase Domain None 192 None Fasta, JSON

Protein domain

Protein domains of 80273.m00037.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 80273.m00037.AA CAMK 58-258 17 1.1e-38 121.75 In-house 95-425 (425) Show / Hide 
Range on Protein: 58-258
Range on HMM: 95-425/425
Sequence Identity: 17% (58 aa)

IDFPGLATVYDICED-------------------DNFIAIPQ---EIVGSG----NLFNYLLPSPL---------------LSESKVAEIAQCMLKCLAY
.| | .   |.. ||                   |... .     | .  |     ||.|.   .                ..|. .. . . ..  ..|
LDHPNIIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHY

LHDIGIVVRNINMQNILISDDSN---------------YPFKLKDYILAKLLDTKN-------------------------LTDICNAETFPS-PEFLRK
.|. .|| | .   |||..|...               .. |. |  .|. .| ..                         ... |    . . || |..
CHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNG

--------------LEYGPPTDIWSLGCIMYVLLCGKFPYFPD--------------VERTMEAFGQIQPDFEKGA------------WQEISPE-----
                |||..|.||.|.|.|..|||..|.  |               ....|   . . ||.               | .|| |     
KGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFV

---ARSIVYRMISINPADRPTAKQLLDEPWI
   ... . .|   .| .|.|..| |. ||.
SQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 80273.m00037.AA Ciliate-E2-Unclassified 67-258 21 1.4e-33 113.81 In-house 87-352 (352) Show / Hide 
Range on Protein: 67-258
Range on HMM: 87-352/352
Sequence Identity: 21% (58 aa)

YDICEDDNFIAIPQEIVGSGNLFNYLLPSPL-----------------LSESKVA-----EIAQCMLKCLAYLHDIG-IVVRNINMQNILISDDS-NYPF
... .|.. | |  | .  |.|..|.  ..                  ..| ...      .. . |..| |||  . |. |.|  .|||....  ||  
FYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYI

KLKDYILAK-----------------LLDTKNLTDIC-NAETFP---SPEFLRKLEYGPP----TDIWSLGCIMYVLLCGKFPYFPDVERT---------
|. |. ..|                  .. ......| . .. |   .|| |.. .|. .     ||||||.|.| .| |..|..   .           
KIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWI

-----MEAFGQIQ---PDFEKGAW----QEISPEARSIVY----RMISINPADRPTAKQLLDEPWI
     .. . .|.   ..| |  |    . .||||  ..     .|.  ||  |.|..|.|  ||.
NNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 80273.m00037.AA Ciliate-E2 57-258 20 3.9e-31 104.1 In-house 88-365 (365) Show / Hide 
Range on Protein: 57-258
Range on HMM: 88-365/365
Sequence Identity: 20% (59 aa)

SIDFPGLATVYDICE--DDNFIAIPQEIVGSGNLFNYLLPSPLLS-----------ESKVAEIAQCMLK---------------CLAYLHDIG-IVVRNI
....| .   |.  .  ||| | .  | .  |.|| |.  ... .           | ....| .  |.               .| |||  . |. |.|
QLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDI

NMQNILISDDSNYPFKLKDYILAKLLDTK-----------NLTD----------------------ICNAETFPSPEFLRKLE---------YGPPTDIW
  .|||.        |. |  |.| .|..           ....                      ||    . .|| |.. .         |.   |||
KPENILF-------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIW

SLGCIMYVLLCGKFPYFPDVERTMEAFGQIQPDFEKG------------AWQEISPEARSIVYR----MISINPADRPT-AKQLLDEPWI
|||.|.| .|.||.|.           ..|. ....              |...|.|.  .  .    |.  .|  |.| ..|.|. ||.
SLGVILYEMLFGKPPF-----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 80273.m00037.AA Pkinase 65-258 26 9.6e-31 109.78 Pfam 64-293 (293) Show / Hide 
Range on Protein: 65-258
Range on HMM: 64-293/293
Sequence Identity: 26% (61 aa)

TVYDICEDDNFIAIPQEIVGSG----NLFNYLL--PSPLL--SESKVAEIAQCMLKCLAYLHDIGIVVRNINMQNILISDDSNYP---FKLKDYILAK--
. ||..||.. | . .| .. |     || |.    .  .  ||  .  ..  .|. |.|.|. ||. | .  .||||. . ...   .|. |  |||  
RLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQF

-LLDTKNLTDICNAETFPSPEFLR-KLEYGPPTDIWSLGCIMYVLLCGKFPYFPD-------VERTMEAFGQIQPDFEKGAWQEIS--------------
 .     .|..|    . .|| .|   .|||. |.||.|||.| .|||..|.  .           ..  .. ...|.   | .||              
DY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFH

---PEARSIVYRMISINPADRPTAKQLLDEPWI
   .|.........  .|..||||.|.|  ||.
NWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 80273.m00037.AA CAMK-Unique 66-258 21 2e-30 97.51 In-house 81-363 (363) Show / Hide 
Range on Protein: 66-258
Range on HMM: 81-363/363
Sequence Identity: 21% (62 aa)

VYDI----CEDDN---------------FIAIPQEIVGSGNLFNYLLP--------------------SPLLSE--SKVAEIAQCMLKCLAYLHDIGIVV
.||.     .|..                . | .|..  | || ...                        .||  . .. | || |  .||.|...|| 
LYDWNNPIFCDRKYPLCDLIIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVH

RNINMQNILISDD--------------SNYPFKLKDYILAKLLDTKNLT----DICNAETFPSP--------------EFLRKLEYGPPT----DIWSLG
|..   ||...                ||.  || |. |.......        .|  . . .|              | .    |. .     ||||||
RDLKLENIMVCYSFKDNNHHRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLG

CIMYVLLCGKFPYFPDVER---------TMEAFGQIQP-DFEKGAWQE---ISPEARSIVYRMISINPADRPTAKQLLDEPWI
 ||| .|||. |  ...|          . |.. . .. .|.. .|.    ||.|| ..| .   . |. | .||.||. .||
VIMYYMLCGCPPFDCECEDRDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
S_TKc 80273.m00037.AA S_TKc 10-258 24 5e-27 97.03 SMART 1-231 (231) Show / Hide 
Range on Protein: 10-258
Range on HMM: 1-231/231
Sequence Identity: 24% (65 aa)

FDELQLVSSSDISRHYHAVEKGTDRKVAILIYMKNPRFKGRIFLQPPSIDFPGLATVYDICEDDNFIAIPQEIVGS--GNLFNYLLPSPL------LSES
.. |... .   .. | ...|.|.|.||| |   .   . .  |.    . | . . ||...| ... .  | ..   |.|| |.   .       ..| 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-EHIRREIQILKK---HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-

KVAEIAQCMLKCLAYLHDIGIVVRNINMQNILISDDSNYPFKLKDYILAKLLDTKNLTDICNAETFPSPEFLRKLEYGP-PTDIWSLGCIMYVLLCGKFP
 .. ... ... |.|.|. ||. | .  .|||...      |. |  ||..|     | .|    . .|| |    ||. . |.||.|||.| .|||. |
HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPP

YFPDVERTMEAFGQIQPDFEKGAWQEISPEARSIVYRMISINPADRPTAKQLLD-------EPWI
.  .......  |              ||||.... ..   .|..|||| ..|         ||.
FP-QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 80273.m00037.AA DCAMKL 81-258 33 1.8e-25 75.72 In-house 95-279 (279) Show / Hide 
Range on Protein: 81-258
Range on HMM: 95-279/279
Sequence Identity: 33% (63 aa)

EIVGSGNLFNYLLPSPLLSESKVAEIAQCMLKCLAYLHDIGIVVRNINMQNILISD--DSNYPFKLKDYILAKLLDT--KNLTDICNAETFPSPEFLRKL
| |  | ||. .  .   .|   | .  |. | | |||. .|| | |   | |. .  |     || |  ||.  .     |  .|   |   || |.. 
EYVQGGDLFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDGEKSLKLCDFGLACHVNGDFGPLYTVCGTPTYVAPEILMET

EYGPPTDIWSLGCIMYVLLCGKFPYFPDVERTMEA-FGQIQ---PDFEKGAWQEISPEARSIVYRMISINPADRPTAKQLLDEPWI
 ||   |||..| | |.|||| || |   ..  |  | ||.   ..|    | .||  |.  . .|   .|  |.||.| .. ||.
GYGCKVDIWAAGVILYILLCG-FPPFRSPDNDQEELFDQIMQGKFEFPMPYWDNISDSAKDLISHMLQVDPEKRYTAEQIMQHPWV
Kinase 80273.m00037.AA RAD53 170-258 29 8.9e-25 70.28 In-house 195-305 (305) Show / Hide 
Range on Protein: 170-258
Range on HMM: 195-305/305
Sequence Identity: 29% (33 aa)

PEFLRKL---------------EYGPPTDIWSLGCIMYVLLCGKFPYFPDV--E--RTMEAFGQIQP----DFEKGAWQEISPEARSIVYRMISINPADR
|| ...                .|..  |.||.||| |..||| .| | |   .  ..| .| ||       |..  | .|| ||.. . .|. ..|  |
PEVITSKGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCG-YPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKR

PTAKQLLDEPWI
.|....|  ||.
YTIDEALNHPWM
Kinase 80273.m00037.AA CAMK2 81-258 34 1.1e-23 77.07 In-house 78-259 (259) Show / Hide 
Range on Protein: 81-258
Range on HMM: 78-259/259
Sequence Identity: 34% (63 aa)

EIVGSGNLFNYLLPSPLLSESKVAEIAQCMLKCLAYLHDIGIVVRNINMQNILI-SDDSNYPFKLKDYILAKLLDTKNLTDICNAET--FPSPEFLRKLE
..|  | ||  .      ||   .   | .|  ... |  ||| | .   |.|. |       || |. ||  ..  .      | |  . ||| |||  
DLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHQNGIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDP

YGPPTDIWSLGCIMYVLLCGKFPYFPDVERTMEAFGQIQP---DFEKGAWQEISPEARSIVYRMISINPADRPTAKQLLDEPWI
|| | |||  | |.|.|| | .| | | |     . ||.    |.    |  . |||.... .|. |||. | ||.. |  |||
YGKPVDIWACGVILYILLVG-YPPFWD-EDQHRLYQQIKAGAYDYPSPEWDTVTPEAKNLINQMLTINPKKRITADEALKHPWI
Kinase 80273.m00037.AA MELK 66-258 28 2.9e-21 69.16 In-house 62-254 (254) Show / Hide 
Range on Protein: 66-258
Range on HMM: 62-254/254
Sequence Identity: 28% (57 aa)

VYDICEDDNFIAIPQEIVGSGNLFNYLLPSPLLSESKVAEIAQCMLKCLAYLHDIGIVVRNINMQNILISDDSNYPFKLKDYIL-AKL---LDTKNLTDI
.| . | .. | .  |    |..|.|..    |.|.    . . ..  .||.|  |   |..  .|.|.  | .. .|| |. | ||     |  ||   
LYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEEETRHFFRQIVSAIAYVHSQGYAHRDLKPENLLF--DEDHHLKLIDFGLCAKTKGRKDYHNLQTC

CNAETFPSPEFLRKLEY-GPPTDIWSLGCIMYVLLCGKFPYFPDVERTMEAFGQIQP-DFEKGAWQEISPEARSIVYRMISINPADRPTAKQLLDEPWI
| .  .  || .. ..| |   |.||.| ..|||.||  |.  | .  |  . .|.   .|.  |  .|||.. .. .|. ..|  |   |.||. ||.
CGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGFLPF--DDDNMMIMYKKIMSGCYEEPKW--LSPESKQLLRHMLQVDPKKRISMKNLLNHPWV
Kinase 80273.m00037.AA RSK 98-258 24 1.9e-20 71.71 In-house 101-278 (278) Show / Hide 
Range on Protein: 98-258
Range on HMM: 101-278/278
Sequence Identity: 24% (44 aa)

LSESKVAEIAQCMLKCLAYLHDIGIVVRNINMQNILISDDSN-YPFKLKDYILAKL--LD-TKNLTDICNAETFPSPEFLR---KLE-YGPPTDIWSLGC
.||. .....    . . .||. ||. | .   |||  |.||    || |  ..|.  .| .. .   |    .  || |.   . . ..   |.||||.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

IMYVLLCGKFPYFP----DVERTMEAFGQIQPDFEKGAWQEISPEARSIVYRMISINPADRPT-----AKQLLDEPWI
.|| .| |. |.      . . .|.  .. . ... ..||..|.||.... .|   .|..|..     |..... ||.
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 80273.m00037.AA CAMKL 172-258 27 2.5e-20 61.44 In-house 205-297 (297) Show / Hide 
Range on Protein: 172-258
Range on HMM: 205-297/297
Sequence Identity: 27% (26 aa)

FLR--KLEYGPPTDIWSLGCIMYVLLCGKFPY-FPDV------ERTMEAFGQIQPDFEKGAWQEISPEARSIVYRMISINPADRPTAKQLLDEPWI
|..  |  .||..||||.| |.|...||..|   ...          .   ...  ..   | ..| ..|..  .|   || .|||..|..  || 
FQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
TyrKc 80273.m00037.AA TyrKc 15-256 16 2.1e-05 -135.42 SMART 1-280 (280) Show / Hide 
Range on Protein: 15-256
Range on HMM: 1-280/280
Sequence Identity: 16% (49 aa)

LVSSSDISR-HYHAVEKGTDRKVAILIYMKNPR------FK--GRIFLQPPSI--DFPGLATVYDICEDD-------NFIAIPQEIVGSGNLFNYLLPSP
..    . . ..  | ||| .   |    |  .      |    ||  .   .  . | .   | .| ..         . |  | .  |.| .||  . 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDAREDFMREARIMCK---LGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

L-LSESKVAEIAQCMLKCLAYLHDIGIVVRNINMQNILISDDSNYPFKLK--DYILAKLLDTK------NLTDIC----NAET-FP----SPEFLRKLEY
  |. ..  ...    .  .|||. ... | .   |.|....       |  |  |.. .. .        .       .. | .|    .|| ... ..
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

GPPTDIWSLGCIMY-VLLCGKFPYFPDVERTMEAFGQIQPDFEKGAWQEISPE--------ARSIVYRMIS----INPADRPTAKQLLDEP
 . .|.|| |  |. ..  |. ||  .... |    ..  . ..|   .. |.        . . .|....     .|.|||| ... .. 
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 80273.m00037.AA CAMKL 67-139 23 0.003231 5.95 In-house 81-165 (297) Show / Hide 
Range on Protein: 67-139
Range on HMM: 81-165/297
Sequence Identity: 23% (20 aa)

YDICEDDNF------IAIPQEIVGSGN--LFNYL--LPSPL--LSESKVAEIAQCMLKCLAYLHDIGIVVRNINMQNILISDDSN
|.. |....      | .  | ...|.  ||.|.   . .   ..|.    . . ..  ..|.|. ||| | |   |||.... |
YEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGN