Gene 91562.m00103 (T.vaginalis)

91562.m00103

Species: T.vaginalis
Alias: 91562.m00103, TvagK0842
External Links:
Annotation:

Classification

Group: CMGC
Family: RCK
Subfamily: MOK

Sequence

Name Sequence Type Origin Length Description Download
91562.m00103.AA Protein None 478 None Fasta, JSON
91562.m00103.kin_dom Protein Kinase Domain None 286 None Fasta, JSON

Protein domain

Protein domains of 91562.m00103.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 91562.m00103.AA RCK 11-296 41 4.1e-137 437.75 In-house 1-298 (298) Show / Hide 
Range on Protein: 11-296
Range on HMM: 1-298/298
Sequence Identity: 41% (124 aa)

WRIINKLGEGSFSEVFKVKSMKNQQFYAIKMLKKRFRSVEEVTRLPEIMCLRALEGNPNIIRLEEVLFDSKHNCLALVFELLDENLFELMRD---HKQPF
  ||..||.|....|.| .. ......||| .|..|.| ||...|.||  ||.|  .|||| | ||..|..   |..|||..|.||...|.|    ....
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKKMKQKFYSWEECMNLREIKSLRKLNPHPNIIKLKEVIRDNDTYQLYFVFEYMDMNLYQMMKDFKERRKYL

DEKT-SL-LIIYQLLKALSIMHAKNLFHRDIKPENCMINKD--------TYELKLADFGSARTTSDTGPFTEYVATRWYRAPECILTSGSYGPAVDIWAV
 |.. |.  |.||.|..|. || .. ||||.|||| |....        .. .|.||||..|   .  |.|.|| |||||||||.|... |   .|||||
PENQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIRSKPPYTDYVSTRWYRAPECLLRCTYYNSPMDIWAV

GCILYEILTTRPLFPGKHQLDQIARIHNILGTPGREVLSQFKQNPNSQINYAFPHRVPQGFRSLLPNASEGIIDLLSKLLVYDPNGRISANEALQHPVF
||| ||. . ||||||   .|||  |....|||  . ......   ||.|. ||  ....  .|.||.|   |.|. |.| .||. ||.|..||||| |
GCIMYELYMLRPLFPGSSEIDQIFKICKVMGTPNKKDWPDGYKL-ASQMNFNFPQCKGMPLKQLIPNCSQDCIELMEKMLQWDPQKRITAQQALQHPYF
Kinase 91562.m00103.AA MOK 11-296 45 2.7e-119 375.7 In-house 1-283 (283) Show / Hide 
Range on Protein: 11-296
Range on HMM: 1-283/283
Sequence Identity: 45% (131 aa)

WRIINKLGEGSFSEVFKVKSMKNQQFYAIKMLKKRFRSVEEVTRLPEIMCLRALEGNPNIIRLEEVLFDSKHNCLALVFELLDENLFELMRDHKQPFDEK
.. | |.|||.|||| |..|... ..|| | .|..| |.|.|  | ||  .| |.  |||. |.||.|| |   |||. ||.| |..||.|  . .  .|
YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQHFESIEQVNNLREIQAMRRLNPHPNILMLHEVVFDRKTGNLALICELMDMNIYELIRGRRHYLPQK

TSLLIIYQLLKALSIMHAKNLFHRDIKPENCMINKDTYELKLADFGSARTTSDTGPFTEYVATRWYRAPECILTSGSYGPAVDIWAVGCILYEILTTRPL
   . .|||.|.|  ||   .||||.|||| .| .|   |||||||| |      |.|||..|||||||||.|| | |   .|.|.|||. |||.  .||
KIMHYMYQLCKSLDHMHRNGIFHRDVKPENILIKQDH--LKLADFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGYYTYQMDMWSVGCVFYEIASLHPL

FPGKHQLDQIARIHNILGTPGREVLSQFKQNPNSQINYAFPHRVPQGFRSLLPNASEGIIDLLSKLLVYDPNGRISANEALQHPVF
|||   .|||..|| ..|||  ..| .|| |    .|| || .   |   |.||...  .... |.  |||  ||.|  ..||| |
FPGVNEVDQISKIHDVMGTPCQKILNKFK-NQSRAMNYDFPFKKGSGIEKLTPNLTKQCLEIMHKMCTYDPDERITAHQVIQHPYF
Kinase 91562.m00103.AA CMGC 11-296 21 1.1e-112 371.85 In-house 1-513 (513) Show / Hide 
Range on Protein: 11-296
Range on HMM: 1-513/513
Sequence Identity: 21% (112 aa)

WRIINKLGEGSFSEVFKVKS--------------MKNQQFYAIKMLKKRFRSVEEV----------TRLPEIMCLRALE----------------GNPNI
  ||.|.|||....|.| .               .......||| .|..|   ..           . | ||..|. |                   .||
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

IRLEEVLFDSK---------------HNCLALVFELLDENLFELMRDHK--------QPFDEKT------------SLLII------YQLLKALS--IMH
..| ... ...                |.| ||||..| .|........        .|..|                 ..      ||.|..|    .|
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

AKN--LFHRDIKPENCMINKDT-------------------YELKLADFGSARTTSD----------------------TGPFTEYVATRWYRAPECILT
 ..   .|||.|||| .||...                   ..||..|||.|| ...                      . |.|.||.|||||||| .| 
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

S---------GSYGPAVDIWAVGCILYEILTT--------RPLFP-----------GKHQLDQIARIHNILGTPG---------------REVLSQFKQN
.         . |....|.|.||||..|..|         .||||           ||. .||...| ..||||                 |   .....
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKL

PNS--------------QINYA----------FPHRVPQGFRSLLPN-----------------------------------ASEGIIDLLSKLLVYDPN
|.               ....           || . |. ...| |.                                   ...  ||||.|.|.|||.
PWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPD

GRISANEALQHPVF
 ||.| .||||| |
KRITAEQALQHPYF
Kinase 91562.m00103.AA MAK 11-296 33 4.2e-95 303.2 In-house 1-352 (352) Show / Hide 
Range on Protein: 11-296
Range on HMM: 1-352/352
Sequence Identity: 33% (119 aa)

WRIINKLGEGSFSEVFKVKS------------------------------MKNQQFYAIKMLKKRFRSVEEVTRLPEIMCLRALEGNPNIIRLEEVLFDS
  .| .|| |.. .| . |.                              ....   |||  || | | || ..| |.  |..|. .|||..| ||. ||
YQMIKQLGDGTYGCVMLAKRQFPLSNILGKQHDIRGTLMDQPKNGHQNYIIDTGEKVAIKRMKKKFYSWEECMNLREVKSLKKLNAHPNIVKLKEVIRDS

KHNCLALVFELLDENLFELMRDHKQ-PFDEKTSLLIIYQLLKALSIMHAKNLFHRDIKPENCMINK----------------DTYELKLADFGSARTTSD
  . | .||| . |||...| | .   | | .   |.|| | .|  ||  . ||||.|||| |..                 | . .|.|||| || .  
ENDHLYFVFEYMKENLYQMMKDRDRRHFPEPVIRNIMYQILQGLAFMHKHGFFHRDMKPENIMCMGPTQYFEKEYMNQIGYQDNELIKIADFGLAREIRS

TGPFTEYVATRWYRAPECILTSGSYGPAVDIWAVGCILYEILTTRPLFPGKHQLDQIARIHNILGTPGREV---------------LSQFKQNPNSQINY
  |.| || ||||||||  | |..|.  .|.||||||  |. | ||||||    |||  |  .|||| ..                .     .  ...|.
KPPYTDYVSTRWYRAPEVLLRSTYYSSPIDMWAVGCIMAELYTFRPLFPGSSEIDQIFKICQVLGTPKKDDDFVNTNHITAPPPGGFWPDGYQLAHMMNF

AFPHRVP---QGFRSLLPNASE-GIIDLLSKLLVYDPNGRISANEALQHPVF
 ||  ||       .|.||.|.   |.|. ..| .||| |  |......| |
RFPQCVPPSIMPLKHLIPNCSQSDAIELMKDMLQWDPNKRPTAQQCCKYPYF
Kinase 91562.m00103.AA S_TKc 11-296 28 4.4e-91 309.83 SMART 1-231 (231) Show / Hide 
Range on Protein: 11-296
Range on HMM: 1-231/231
Sequence Identity: 28% (85 aa)

WRIINKLGEGSFSEVFKVKSMKNQQFYAIKMLKKRFRSVEEVTRLPEIMCLRALEGNPNIIRLEEVLFDSKHNCLALVFELLDE---NLFELMRDHKQP-
..|..|.|.|.|..|.|..  | .. .|||..|         . . || .|.   . |||..| .|  |   ..| .|.|..|    .||....... . 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----FDEKTSLLIIYQLLKALSIMHAKNLFHRDIKPENCMINKDTYELKLADFGSARTTSDTGPFTEYVATRWYRAPECILTSGSYGP-AVDIWAVGCIL
    |.| .   ..||...||  .| ..  |||.|||| ....   ..|..|||.||        | .. |.||.||| .    .||. ..|.|..||||
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCIL

YEILTTRPLFPGKHQLDQIARIHNILGTPGREVLSQFKQNPNSQINYAFPHRVPQGFRSLLPNASEGIIDLLSKLLVYDPNGRISANEALQ-------HP
|| |. .|.||      |.... ...|                                     |.  .|...|.|..||. |..| ||||       ||
YEMLCGYPPFP------QMQMMFKKIG-------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHP

VF
 |
WF
Kinase 91562.m00103.AA CDK 11-296 31 6e-90 287.95 In-house 1-284 (284) Show / Hide 
Range on Protein: 11-296
Range on HMM: 1-284/284
Sequence Identity: 31% (101 aa)

WRIINKLGEGSFSEVFKVKSMKNQ-----QFYAIKMLKKRFR-SVEEVTRLP-----EIMCLRALEGNPNIIRLEEVLFDSK---------HNCLALVFE
  ...|.|||.. .|.| ......     |..|.|...       || . .|     || .|. |  .|||..| .|  ...          | | .|||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFE

LLDENLFELMRDHKQPFDEKTSLLIIYQLLKALSIMHAKNLFHRDIKPENCMINKDTY----ELKLADFGSARTTS-------DTGPFTEYVATRWYRAP
 .|  | ..|.             ...|||..|. .| ..  |||.|| | .||..       ||.|||| ||  .        . ..|  | |.|||||
YMDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAP

ECILTSGSYG--PAVDIWAVGCILYEILT---TRPLFPGKHQLDQIARIHNILGTPGREVLSQFKQNPNSQINYAFPHRVPQGFRSLLPNASEGIIDLLS
|  | |  |.  ...|.|.||||..|..|    .|||||.  .||. .| .|.|||  ..   ... |.                           |||.
ELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY--------------------------DLLN

KLLVYDPNGRISANEALQHPVF
|.|.|||. |||| .||||| |
KMLCYDPKKRISAEQALQHPYF
Kinase 91562.m00103.AA Pkinase 11-296 30 4.7e-83 287.02 Pfam 1-293 (293) Show / Hide 
Range on Protein: 11-296
Range on HMM: 1-293/293
Sequence Identity: 30% (95 aa)

WRIINKLGEGSFSEVFKVKSMKNQQFYAIKMLKKRFRSVEE-VTRLP--EIMCLRALEGNPNIIRLEEVLFDSKHNCLALVFELLDE-----NLFELMR-
..|. |.|.|||..|.| .  .... .|.| .||| .. .. .|..   ||  .. | . |||.|| ..  |..| .  .|.|...       ||.... 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIY--MVMEYCEGGLYVMDLFDYIST

DHKQPF--DEKTSLLIIYQLLKALSIMHAKNLFHRDIKPENCMINKDTYEL----KLADFGSART--TSDTGPFTEYVATRWYRAPECILTSGSYGPAVD
. . .|  .|..   ..||.|..|  .|...  |||.||||..|. .....    |..|||.|.   .   . .| .. |.||.||| |...  |||.||
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

IWAVGCILYEILTTRPLFPGK----HQLDQIARIHNILGTPGREVLSQFKQNPNSQINYAFPHRVPQGFRSLLPNASEGIIDLLSKLLVYDPNGRISANE
.|..|||||| |. ||.|||.    . .||...| .|.|.| ..  ..   .... ...   |   . .. . .|.||  .|.....| .||. |..| .
MWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRH-W-H---F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQ

ALQHPVF
.|||| |
ILQHPWF
Kinase 91562.m00103.AA CDC2 11-296 35 1.1e-77 238.21 In-house 1-301 (301) Show / Hide 
Range on Protein: 11-296
Range on HMM: 1-301/301
Sequence Identity: 35% (111 aa)

WRIINKLGEGSFSEVFKVKSMKNQQFYAIKMLKKRFRSVEEV-----TRLPEIMCLRALEGNPNIIRLEEVLFDSKHNCLALVFELLDENLFELMR---D
   |.|.|||.. .|.| | |. .|  |.|.   |  . .|      | . || || .|   |||..|..|..    | | .||| || .| ..|.    
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKI--RLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ---NKLYMVFEYLDMDLKKYMDMSIP

HKQPFDEKTSLLIIYQLLKALSIMHAKNLFHRDIKPENCMINKDTYELKLADFGSART-TSDTGPFT--EYVATRWYRAPECILTSGSYGPAVDIWAVGC
 ...... .   ..||.|....  |..  .|||.|| |  |.|.   .|.|||| ||. .    . |    | |.||||||  | .  |  .||.|..||
KNKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGN-IKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGC

ILYEI---LTTRPLFPGKHQLDQIARIHNILGTPGREVLSQFKQNPNSQINYAFPHRVPQGFRSLLPN---------ASEGIIDLLSKLLVYDPNGRISA
|..|.    | .|||.|. . ||. .|  |||||  . .   .|.|    .  ||   ||......||         . .  ||||...|.|||. ||||
IFAEMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPD--YKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISA

NEALQHPVF
 |||||| |
KEALQHPYF
Kinase 91562.m00103.AA MAPK 11-296 32 2e-77 263.53 In-house 1-328 (328) Show / Hide 
Range on Protein: 11-296
Range on HMM: 1-328/328
Sequence Identity: 32% (106 aa)

WRIINKLGEGSFSEVFKVKSMK------NQQFYAIKMLKKRFRSVEEVTR-LPEIMCLRALEGNPNIIRLEEVLFDS-----KH----NCLALVFELLDE
 .|. ..|.|..  |....  .      .... ||| . . |...    | . ||..|| . . .|||.| ...  .     ..    | . .|.|| . 
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

NLFELMRDHKQPFDEKTSLLIIYQLLKA--LSIMHAKNLFHRDIKPENCMINKDTYELKLADFGSARTTSDT------------GPF----TEYVATRWY
.|  ...  . | ...    ..||.|..  |  .|  |  |||.||.|  .|..  .||..||| ||.. ..            . .    |||||||||
DLHQIIKSQQ-PLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENC-DLKICDFGLARSIDPEYHHHHQQDDPHCF-QKMHMTEYVATRWY

RAPECILT--SGSYGPAVDIWAVGCILYEILT-TRPLFPGKHQLDQIARIHNILGTPGREVLSQFK--QNPNSQINYA--FPHRVPQGFRSLLPN----A
|||| .|   .  |  |||.|.||||. | ||  .||||||. .||. .| ..|||| .|.... .  ... . |     .|.. .. .....||    |
RAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNA

SEGIIDLLSKLLVYDPNGRISANEALQHPVF
.   ||||.|.|| ||. ||.. |||||| |
NPQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase 91562.m00103.AA ERK7 11-296 34 6.2e-70 238.3 In-house 1-292 (292) Show / Hide 
Range on Protein: 11-296
Range on HMM: 1-292/292
Sequence Identity: 34% (100 aa)

WRIINKLGEGSFSEVFKVKSMKNQQFYAIKMLKKRFRSVEEVTR-LPEIMCLRALEGNPNIIRLEEVLFDSKHNCLALVFELLDENLFELMRDHKQPFDE
. |. .|| | .  | |.   . .|  |.|     ||      |   ||| |..... |||||| .|.  .    . |||| ..  |    | . .   .
YEIRKRLGKGAYGIVWKAYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVIRADNDRDIYLVFEFMETDLHAVIR-KGNILKD

KTSLLIIYQLLKALSIMHAKNLFHRDIKPENCMINKDTYELKLADFGSARTTSDTG-------PFTEYVATRWYRAPECILTSGSYGPAVDIWAVGCILY
     |.||||.|.  ||  |. |||.|| | ... .   .|..||| ||. ...          |||||||||||||  | |  | ..|| | .|||| 
IHKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECM-VKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGCILG

EILTTRPLFPGKHQLDQIARIHNILGTPGREVLSQFKQNPNSQINYAFPHRVPQGFRSLLPNASEGIIDLLSKLLVYDPNGRISANEALQHPVF
|.|. .|.|||   ..|| .| .... | .| .   . .  ...  . ... .. .  ..|....  |||| .|||. |. |..|..|||||  
EMLRGKPMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMNQQKRKTLDQMMPQCCDDAIDLLKRLLVFNPKKRLTAEQALQHPYV
Kinase 91562.m00103.AA CDK5 11-296 35 7.2e-70 219.81 In-house 1-287 (287) Show / Hide 
Range on Protein: 11-296
Range on HMM: 1-287/287
Sequence Identity: 35% (105 aa)

WRIINKLGEGSFSEVFKVKSMKNQQFYAIKMLKKRFRSVEE---VTRLPEIMCLRALEGNPNIIRLEEVLFDSKHNCLALVFELLDENLFELMRDHKQPF
.  ..|.||| .  |.| .  . . ..|.|    |  |  |    | . ||  |. |   .||.||  |.   |   | |||| .|. |   | . .   
YEKMEKIGEGTYGTVYKARNKETHEIVALKRV--RLDSEDEGVPSTAIREICLLKELK-HKNIVRLHDVIHSEKK--LTLVFEFCDQDLKKYMDSCNGEM

DEKTSLLIIYQLLKALSIMHAKNLFHRDIKPENCMINKDTYELKLADFGSARTTS-DTGPFTEYVATRWYRAPECILTSGSYGPAVDIWAVGCILYEIL-
| ..   ..||||| |.. |...  ||| || | .|||   |||||||| ||        ..  | | |||.|   . |  |   .|.| .|||. |.  
DMHIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNG-ELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMAN

TTRPLFPGKHQLDQIARIHNILGTPGREVLSQFKQNPNSQ-INYAFPHRVPQG-FRSLLPNASEGIIDLLSKLLVYDPNGRISANEALQHPVF
. ||||||  . ||  ||  |.|||  .      . |. .    ..| . ..  . .. |. .|   |||.|.|...|| ||||..||.|| |
AGRPLFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase 91562.m00103.AA p38 87-296 38 9.2e-62 209.8 In-house 85-289 (289) Show / Hide 
Range on Protein: 87-296
Range on HMM: 85-289/289
Sequence Identity: 38% (81 aa)

LVFELLDENLFELMRDHKQPFDEKTSLLIIYQLLKALSIMHAKNLFHRDIKPENCMINKDTYELKLADFGSARTTSDTGPFTEYVATRWYRAPECILTSG
.| .. .  |  .|.  .  . .    ...||.|..|   |. .  ||| || |  .| |  ||.  ||| || . |    |.||||||||||| .|  .
MVTHFMGADLNNIMKCQR--LSDDHIQFLVYQILRGLKYIHSAGIIHRDLKPSNIAVNEDC-ELRILDFGLARHCDDE--MTGYVATRWYRAPEIMLNWM

SYGPAVDIWAVGCILYEILTTRPLFPGKHQLDQIARIHNILGTPGREVLSQFKQNPNSQINYAFPHRVPQGFRSLLPNASEGIIDLLSKLLVYDPNGRIS
 |  .|||| ||||. |..| |.||||.  .||. || ...||| .|...  ..          | .  . |......|.   |||| |.|. ||  ||.
HYTQTVDIWSVGCIMAELITGRTLFPGDDHIDQLQRIMKVCGTPDEEFWQKIQSEEARNYIQSYPQMPRRDFHHVFMGANPQAIDLLEKMLELDPDKRIT

ANEALQHPVF
| ||.||| |
AEEAMQHPYF
Kinase 91562.m00103.AA TyrKc 11-296 23 1e-12 -16.91 SMART 1-280 (280) Show / Hide 
Range on Protein: 11-296
Range on HMM: 1-280/280
Sequence Identity: 23% (73 aa)

WRIINKLGEGSFSEVFKVKSMKNQQFYAIKMLKKRFRSVEEVTRLPEIMCLRAL-EGNPNIIRLEEVLFDSKH-----NCLALVFELLDE-NLFELMRDH
 . . ||||| | ||.| .     .  |.||||.    .|.  |  |.  .. |   .|||.||  |  ...        | .|.|. .  .| .  |.|
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMR--EARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

KQPFDEKTSLLIIYQLLKALSIMHAKNLFHRDIKPENCMINKDTYELKLADFGSARTTSDT---------GPF-----TEY-VATRWYRAPECILTSGSY
.  .  |. | . .|  .  .  | ||. |||.   ||.....    | .||| .|   |                  . . .  ||. |||||   | .
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM-APECI-NYGKF

GPAVDIWAVGCILYEILTT-RPLFPG-----KHQLDQIARIHNILGTPGREV---LSQFKQNPNSQINYAFPHRVPQGFRSLLPNASEGIIDLLSKLLVY
 .. |.|. |  ..||.|   .  ||     .   . |... .    |  .    .|                     |    . ... . .. ..   .
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS---------------------F----VCCPDEMYQIMKQCWHE

DPNGRISANEALQHPVF
||. | . .|   |  |
DPEDRPTFSEI--HECF
Kinase 91562.m00103.AA Pkinase_Tyr 11-206 29 0.000459 14.39 Pfam 1-209 (270) Show / Hide 
Range on Protein: 11-206
Range on HMM: 1-209/270
Sequence Identity: 29% (63 aa)

WRIINKLGEGSFSEVFKVKSM----KNQQFYAIKMLKKRFRSV----EEVTRLPEIMCLRALEGNPNIIRLEEVLF-DSKHNCLALVFELLDE-NLFELM
 ... |||||.| ||.| .      ....  |.||||    .     |.  |  |.  .. |  .|||.||  |   ....| . .|.|.    .| .  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR--EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

RDH---KQPFDEKTSLLIIYQLLKALSIMHAKNLFHRDIKPENCMINKDTYELKLADFGSARTT--SDTG-PFTE--YVATRWYRAPECILTSGSYGPAV
|.|   |||.. |. | . .|  |...  ..||. |||.   ||.....    | .||| ||.    |.    ..   .  .|. ||||| ..  .  . 
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENN-VVKICDFGLARDIYNDDYYYRKRGGGKLPIKWM-APECINYGK-FTTKS

DIWAVGCILYEILT
|.|. |  ..||.|
DVWSFGVLMWEIFT
Kinase 91562.m00103.AA p38 11-50 25 0.03408 2.97 In-house 1-43 (289) Show / Hide 
Range on Protein: 11-50
Range on HMM: 1-43/289
Sequence Identity: 25% (11 aa)

WRIINKLGEGSFSEVFKVKSMKNQQF---YAIKMLKKRFRSVE
 . .  .|.|.. .| |.   . .|     ||| | . | |..
YQNLQPVGSGAYGQVCKAEDRRTGQKRRYVAIKKLMRPFQSEI