Gene 81399.m00045 (T.vaginalis)
81399.m00045
Species: T.vaginalis
Alias: 81399.m00045, TvagK0901
External Links:
Annotation:
Group:
CAMK
Family:
CAMK-Tvag3
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
---|---|---|---|---|---|
81399.m00045.AA | Protein | None | 272 | None | Fasta, JSON |
81399.m00045.kin_dom | Protein Kinase Domain | None | 236 | None | Fasta, JSON |
Protein domains of 81399.m00045.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 81399.m00045.AA | CAMKL | 22-257 | 26 | 2.3e-43 | 136.16 | In-house | 15-297 (297) | Show / Hide |
Range on Protein: 22-257 Range on HMM: 15-297/297 Sequence Identity: 26% (76 aa) VWCCSD-KRTGKKVVIKSFPKEVID-NSFYEN---------------ELHITELAQ---GDNIIQLLDRFETQVS------YNLVLEQGECD---LFDYI | . . . ||.|| || |. | . . .. | .| .. . |||.|.. .||. ..||.| . ||||| VKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYI MNNG------PISEAKFMNTFGDLSKALERLHHRNILHKDIKPENIVIVGDSYS---FIDFGLSEIMSN-----VNQNNAFVGTTLFTAPEVVLN--KSY ..| | .||... | . |.. .| ..| | ||||||| . . . ||||.| .. . . . | |. . |||... |.| VKHGHRRGRMPEHEARRY--FRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPY T-PDSDIYSFGIVMFFALSGELPFDCEN-------SFQYVMNQINTPPDMNALCNRHISQQIILVIQRMLSPSPKDRPSISEIISTLWP | || | |..... . |.||||... . | ...|.. . |.| . . |..|| . |..||.| .| . | DGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG--YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM |
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S_TKc | 81399.m00045.AA | S_TKc | 7-257 | 26 | 9.8e-43 | 149.21 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 7-257 Range on HMM: 1-231/231 Sequence Identity: 26% (71 aa) YEQIREIFHGENTVAVWCCSDKRTGKKVVIKSFPKEVIDNSFYENELHITELAQGDNIIQLLDRFETQVSYNLVLEQGEC---DLFDYIMNNGP------ || .|.| .| |..| .|.||..| || . ..|. | . . .||..|.| |.. .. .|.| . |||||| ..|. YEILRKIGKG-AFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP ISEAKFMNTFGDLSKALERLHHRNILHKDIKPENIVIVGDSYSFIDFGLSEIMSNVNQNNAFVGTTLFTAPEVVLNKSYTP-DSDIYSFGIVMFFALSGE ..| . . .||| .| ..|.| |.||||| . .||||. .. . |.|| . ||||. .|.. .|..|.|.... |.|. FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGY LPFDCENSFQYVMNQINTPPDMNALCNRHISQQIILVIQRMLSPSPKDRPSISEIIS-------TLWP ||. | ....| |.. . |...| |..||.. |. | PPFP---QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | 81399.m00045.AA | CAMK | 22-257 | 17 | 7.2e-41 | 128.95 | In-house | 10-425 (425) | Show / Hide |
Range on Protein: 22-257 Range on HMM: 10-425/425 Sequence Identity: 17% (75 aa) VWCCSDKRTG------------KKVVIKSFPKEVIDN-----------------------------SFYENELHITELAQ-------GDNIIQLLDRFE- | | .|.|. .|| || .|. ... . ..|..| . | |||.|.. .| VKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNIIKLYEVYED -------TQVS------------YNLVL------EQGEC--DLFDYIMNNGP---------------ISEAKFMNTFGDLSKALERLHHRNILHKDIKPE .. . . .|. . || |||||| .|. ..|. | . |.. .| .|| | |.||| PHYFKNTND-YETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPE NIVIVGDSYSF------------------IDFGLSEIMSNVNQNNA------------------------FVGTTLFTA-PEVVLNKS------------ || .. .. .. ||||.. .. ..|. |.|| . | |||.. |. NILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEK --YTPDSDIYSFGIVMFFALSGELPFDCE----------------NSFQYVMNQINT-PPDMNAL-----------------CNRHISQQIILVIQRMLS |.| .|. | |..... |.|..||. . . |. .|. . ||.. . ..||. . |..|| PYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHH-FVSQECKDLIRKMLQ PSPKDRPSISEIISTLWP . |..|..|... . | VDPEKRMTIEQCLNHPWM |
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Kinase | 81399.m00045.AA | Pkinase | 22-255 | 25 | 9.2e-41 | 145.21 | Pfam | 15-293 (293) | Show / Hide |
Range on Protein: 22-255 Range on HMM: 15-293/293 Sequence Identity: 25% (73 aa) VWCCSDKRTGKKVVIKSFPKEVIDNSFYEN-----ELHITELAQGDNIIQLLDRFETQVSYNLVLEQGEC-----DLFDYIM--NNGPI--SEAKFMNTF |. | .| |||.|..| ..|. .. .. .. |..| . .||..|.| ||. .. .|.| |. ||||||. ..|.. || . . VYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYM GDLSKALERLHHRNILHKDIKPENIVIVGDSYSF------IDFGLSEI--MSNVNQNNAFVGTTLFTAPEVVL-NKSYTPDSDIYSFGIVMFFALSGELP . ..|| .| ..|.| |.||||| |. . . .||||.. | .. |.|| . ||||.. .. |.| .|..|.|.... |.|..| YQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPP FDCE-----NSFQYVMNQINTPPDMNALCNRHI------------------SQQIILVIQRMLSPSPKDRPSISEIIST--L |. . .. ......| || . . . |. . .| ..| . ||.||.. .| . FPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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Kinase | 81399.m00045.AA | Ciliate-E2 | 7-257 | 21 | 6.7e-35 | 117.23 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 7-257 Range on HMM: 1-365/365 Sequence Identity: 21% (82 aa) YEQIREIFHGENTVA-VWCCSDKRTGK------------------KVVIKSFPKEVIDNS---FYENELHIT----------------ELAQGDNIIQLL |. |. | |. . . |. |......| || || . .... .. . ..|.|| |. . .|||.. YKFIKKI--GQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMY DRFE--TQVSYNLVLEQGEC-DLFDYIMNN-----------GPISEAKFMNTFGDLSK---------------ALERLHHRN-ILHKDIKPENIVIVGDS . |. .. .. ||.| . |||||| || ....| . . . . . ||| || .| |.| |||||||.. ECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF---- YSFIDFGLSEIMSNVNQNNA--------------------------------FVGTTLFTAPEVVLNKS---------YTPDSDIYSFGIVMFFALSGEL |||||| . .. |||. ..|| . |||.. .|. |. .||.|.|..... |.|.. IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP PFDCENSFQYVMNQINT-PPDMNALC--------------NRHISQQIILVIQR----MLSPSPKDRPS-ISEIISTLWP || ..|| . | . . . ..||. . |.. || |. |.. ...|. | PF---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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Kinase | 81399.m00045.AA | Ciliate-E2b | 85-200 | 31 | 8.2e-34 | 100.24 | In-house | 84-211 (272) | Show / Hide |
Range on Protein: 85-200 Range on HMM: 84-211/272 Sequence Identity: 31% (40 aa) ECDLFDYIMNNG--PISEAKFMNTFGDLSKALERLHHRNILHKDIKPENIVIVGDSYS-FIDFGLSEIMSNVNQ----NNAFVGTTLFTAPEVVL----- . .|||.| . | .|. .. . ..|| ||..||.. ||||||| . ..| ||.|.. .|. |. . .|| . |||.. GMELFDVIREIGRLLLSTYDSQFYIASICLCLEYLHNQNIIYRDIKPENIMVDHKGYMKLIDMGTAKHMYKKNEQMTRTFTIIGTPHYMAPEIIQSLQPG NKSYTPDSDIYSFGIVMFFALSGELPFD .| || .||.|.||. .. ..| .|.. GKGYTYKVDIWSVGICLYEFMCGYVPWA |
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Kinase | 81399.m00045.AA | Ciliate-E2-Unclassified | 22-257 | 19 | 2.8e-33 | 112.78 | In-house | 15-352 (352) | Show / Hide |
Range on Protein: 22-257 Range on HMM: 15-352/352 Sequence Identity: 19% (67 aa) VWCCSDKRTGKKV-------VIKSFPKEVIDNSFYENELHITELAQGD---------------------NIIQLLDRFETQVSYNLVLEQGE-CDLFDYI |. | .| .. .. .|... . | |. | . ..|. . .|. ... |... .|.|. | ||..|| VYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYI MNNGP-----------------ISEAKFM-----NTFGDLSKALERLHHRN-ILHKDIKPENIVIVGD----SYSFIDFGLSEIMSNVNQ---------- ... ..| . . | . ..|| ||| | |.| |||||||.. . ||||.| . |. KKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQ ------NNAFVGTTLFT----APEVVLNKSYTPD----SDIYSFGIVMFFALSGELPFDCENSFQ-YVMNQINTPP------DMNALCNR---------- . |.|| . |||| .. | .||.|.|..... | |..||...|. | ........ . ... IWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWI-NNAYRKQLYQNIKQKNIQFPKFPWQ ----HISQQIILVIQ----RMLSPSPKDRPSISEIISTLWP |.|.. . |. .|| |. |.....|. | QIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF |
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Kinase | 81399.m00045.AA | MARK | 25-257 | 30 | 1.4e-29 | 94.0 | In-house | 18-262 (262) | Show / Hide |
Range on Protein: 25-257 Range on HMM: 18-262/262 Sequence Identity: 30% (78 aa) CSDKRTGKKVVIKSFPKEVIDN----SFYENELHITELAQGDNIIQLLDRFE--TQVS-YNLVLE-QGECDLFDYIMNN--GPISEAKFMNTFGDLSKAL . .|.||.|| || .|. .. . . |..| . . |||.|.. .| | .|..| .. .|.||| . |...| | . |. ACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGRLHEEEARRIFRQIVSAV ERLHHRNILHKDIKPENIVIVGDSYS-----FIDFGLSEIMSNVNQNNAFVGTTLFTAPEVVLNKSYT-PDSDIYSFGIVMFFALSGELPFD--C--ENS . .| .|| | ||||||| | |. ||||.| . . . | | || . |||..| | |. | ||.| |.|..| ..| .||| . .. NYCHSKNIVHRDIKPENILI--DENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKE FQYVMNQINTP-PDMNALCNRHISQQIILVIQRMLSPSPKDRPSISEIISTLWP . .. . . |.. .| .. |||.| . |..||.|.|| . | LYKKILRGKYDIPCH-------VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM |
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Kinase | 81399.m00045.AA | TKL | 109-255 | 19 | 4.2e-29 | 101.95 | In-house | 140-364 (364) | Show / Hide |
Range on Protein: 109-255 Range on HMM: 140-364/364 Sequence Identity: 19% (44 aa) DLSKALERLHHRN--------ILHKDIKPENIVIVGDS---------------YSFIDFGLSEIMSNVN--------------------QNNAFVGTTLF | ..... || .| |.| |.|..|| . . ||||| ||. . ... .||. . DIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRW TAPEVVLNK----------------SYTPDSDIYSFGIVMFFALSGELPFDCENSF------------QYVMNQINTPPDMNA-------LCNRHISQQI |||| .. .|.. .|.||||||.. |....|....... .| . . || . .. .. ... MAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSM ILVIQRMLSPSPKDRPSISEIISTL . .|. .. |..||| .||...| KKLMQDCWDHDPEKRPSFQEILKRL |
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Kinase | 81399.m00045.AA | SNRK | 30-257 | 29 | 1.1e-27 | 87.45 | In-house | 23-254 (254) | Show / Hide |
Range on Protein: 30-257 Range on HMM: 23-254/254 Sequence Identity: 29% (70 aa) TGKKVVIKSFPKEVIDN---SFYENELHITELAQGDNIIQLLDRFETQVSYNLVLEQGE-CDLFDYIMN-NGPISEAKFMNTFGDLSKALERLHHRNILH ||.|| .| | .|. . | . | | ||. | . .|| |.|| |. |..|||| . ..| . | . .|.. |.. . | TGEKVAVKVIDKTKMDEVSKAHLFQEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDGYDMYDYIMKHEKGLCEDLARKYFCQIMHAIDYCHQLHVVH KDIKPENIVIVGDS--YSFIDFGLSEIMSNVNQNNAFVGTTLFTAPEVVLNKSY-TPDSDIYSFGIVMFFALSGELPFDCENSFQYVMNQINTPPDMNAL .|.||||.| ||| | .. . . | . |||..| || | ||.| |.... . |..||. | . . | RDLKPENVVFFEKQGMVKLTDFGFSNKFMPGEKLETSCGSLAYSAPEILLGDSYDAPAVDIWSLGVILYMLVCGQAPFQEANDSETLTMIM----DCKYT CNRHISQQIILVIQRMLSPSPKDRPSISEIISTLWP |.|.. .||.|| || | |. || |. | VPDHVSDECRDLIQSMLVRDPKKRASLEEIVSHSWV |
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Kinase | 81399.m00045.AA | CAMK-Unique | 7-204 | 22 | 4.6e-27 | 86.21 | In-house | 1-298 (363) | Show / Hide |
Range on Protein: 7-204 Range on HMM: 1-298/363 Sequence Identity: 22% (67 aa) YEQIREIFHGENTVAVWCCSDKRTGKKVVIKSFPK---EVIDNSF------------------YENELHITELAQGDNIIQLLDR----FETQV------ |. .| | ||. . | | |. |||| ..|.. | . . . ...|. | . |||.|.| |.. YKMHRIIGHGNFG-HVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDL ---------SYNLVLEQGECD-LFDYIMN--------------------NGPISE--AKFMNTFGDLSKALERLHHRNILHKDIKPENIVIVGDSYSFI- . .|.| .. |||.|. .|. || . . . | |.. .| .| | |.|.|||.. .|||. IIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMV---CYSFKD -------------------DFGLSEIMSNVNQNN---AFVGTTLFTAP--------------EVVLNKSYTPDS----DIYSFGIVMFFALSGELPFDCE ||||. ... . ...|| .. || ||. . | . || | | .|.. |.|..||||| NNHHRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCE NS .. CE |
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Kinase | 81399.m00045.AA | ULK | 27-253 | 22 | 1.2e-25 | 88.01 | In-house | 21-320 (324) | Show / Hide |
Range on Protein: 27-253 Range on HMM: 21-320/324 Sequence Identity: 22% (68 aa) DKRT---GKKVVIKSFPKEVIDNSFYENE------------LHITELA--QGDN--IIQLLDRFETQVS--YNLVLEQGEC-DLFDYIMNNGP------- .|.| ...| .| .| . .. .|.| . .| .. | |..|.| |||. . . ...| .. ||..|| .|.. NKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPETEEK --ISEAKFMNTFGDLSKALERLHHRNILHKDIKPENIVIVGDSYS-------------FIDFGLSEIMSN----VNQNNAFV------GTTLFTAPEVVL .|| . . | .. .. || .|| | ||||.|| | . . |||.. . | ... .| || |. ||... KRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQ ----NKSYT-PDSDIYSFGIVMFFALSGELPFDCENSFQYV----------------MNQINTPPDMNALCNRHISQQIILVIQRMLSPSPKDRPSISEI .| |. .||.|.|.... | |. || . ... ... . ..... . .||.... |.||| .||| |. || GQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPP-KDPKISPECKDLIRRMLQYDEKDRISWEEI IS .. FN |
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Kinase | 81399.m00045.AA | TyrKc | 12-255 | 17 | 3.9e-09 | -74.94 | SMART | 14-280 (280) | Show / Hide |
Range on Protein: 12-255 Range on HMM: 14-280/280 Sequence Identity: 17% (51 aa) EIFHGENTVAVWCCSDKRTGKKVVIKSFPKEVIDNSFYENELHITEL-AQGDNIIQLLDRFETQ-------VSYNLVLEQGEC-DLFDYIMNNGP-ISEA |...|. . .| .|. .. |.. ..| . .||..|. .| . .|.| . || ||. ...| .. . EVYKGTWK------------IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMK KFMNTFGDLSKALERLHHRNILHKDIKPENIVIVGDSYSFI----DFGLSEIMSNV------NQNNAF----VGTTLF----TAPEVVLNKSYTPDSDIY .. . . .. | ||..|. | |. |. . . . ||||| . . | |.. .|||. . .|. ||.. DLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVW SFGIVMFFALSGELPFDCE-----NSFQYVMNQINTPPDMNALCNRHI---------SQQIILVIQRMLSPSPKDRPSISEIISTL |||..|. .. . . | | |.... . . . . .. . .... |.|||. |||.. . SFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQ---GYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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Kinase | 81399.m00045.AA | Pkinase_Tyr | 166-190 | 40 | 0.000204 | 15.58 | Pfam | 181-205 (270) | Show / Hide |
Range on Protein: 166-190 Range on HMM: 181-205/270 Sequence Identity: 40% (10 aa) TAPEVVLNKSYTPDSDIYSFGIVMF .|||. .. .| ||..|||..|. MAPECINYGKFTTKSDVWSFGVLMW |
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Kinase | 81399.m00045.AA | Pkinase_Tyr | 242-255 | 57 | 0.193455 | 5.5 | Pfam | 257-270 (270) | Show / Hide |
Range on Protein: 242-255 Range on HMM: 257-270/270 Sequence Identity: 57% (8 aa) PKDRPSISEIISTL |.|||. |||.. | PEDRPTFSEIHEQL |