Gene TVAG_207420 (T.vaginalis)
TVAG_207420
Species: T.vaginalis
Alias: TVAG_207420, TvagK1057
External Links:
Annotation:
Group:
CMGC
Family:
CMGC-Tvag1
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| TVAG_207420.AA | Protein | None | 825 | None | Fasta, JSON |
| TVAG_207420.kin_dom | Protein Kinase Domain | None | 293 | None | Fasta, JSON |
Protein domains of TVAG_207420.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Pkinase | TVAG_207420.AA | Pkinase | 191-293 | 25 | 4.5e-07 | 26.09 | Pfam | 175-293 (293) | Show / Hide |
Range on Protein: 191-293 Range on HMM: 175-293/293 Sequence Identity: 25% (33 aa) RFYRAPEW-N-ANPMFCESDCWSLGCLLAEYMIFAGPLFGSI----SINDQMVRTQMICGPAPAFLNWPPAPQSRKTVFPP----------------IIA ..|.|||. . ... ..| ||.||.|.| . |.| . . .|||.. ..| || . | . . . |. . |.. .| PWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRHWHFHWTFHNWSEECKDFIK DMLSYDPRKRPLLCIHVSNQILQF--I ..| .|| ||| |||| . WCLCKDPKKRPT-----AEQILQHPWF |
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| Kinase | TVAG_207420.AA | DYRK1 | 191-238 | 42 | 6.5e-05 | 12.63 | In-house | 167-214 (321) | Show / Hide |
Range on Protein: 191-238 Range on HMM: 167-214/321 Sequence Identity: 42% (21 aa) RFYRAPEWNANPMF-CESDCWSLGCLLAEYMIFAGPLFGSISINDQMVR ||||.|| . . . | |||||.| | | ||| . ||| . RFYRSPEVLLGIEYDMAIDMWSLGCILVE-MHTGEPLFSGSNEVDQMNK |
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| Kinase | TVAG_207420.AA | CK2 | 208-238 | 38 | 0.00013 | 8.86 | In-house | 178-208 (288) | Show / Hide |
Range on Protein: 208-238 Range on HMM: 178-208/288 Sequence Identity: 38% (12 aa) DCWSLGCLLAEYMIFAGPLFGSISINDQMVR | |||||..| .. |.| . .||.|. DMWSLGCMFASMIFKKEPFFHGHDNYDQLVK |
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| S_TKc | TVAG_207420.AA | S_TKc | 22-293 | 12 | 0.00038 | -116.11 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 22-293
Range on HMM: 1-231/231
Sequence Identity: 12% (40 aa)
YEA------------YIASHKVSKRKFLITKYNLELLNVQPKLLYNRLMFLIKNYRMFRCECVFFQGHLASLEVLNPKILGKFIKYFYVVEPLPM--VTL
|| | . || ..|.. | . . . ... . | | . . . . . ... | | .. .|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-------HHPNIVKLYDVFQD---------DHLYMVMEYCDGDLGDL
ADFATENQ-------MSKSILLEKLPNLLSTIAMMHSVKFAYLNISP---------------FTIIVDGVFWLRPPSLMPYSSPKNCFAPPPQGFRAEYR
|. ... .. . ... .. .|| .. . . | . ..
FDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQL---------------------------------
SVNEM---RFYRAPEWNANPMFCESDCWSLGCLLAEYMIFAGPLFGSISINDQMVRTQMICGPAPAFLNWPPAPQSRKTVFPPIIADMLSYDPRKRPLLC
. . ..|.||| .|..| ||.||.|.| . |.| || .. ..| . . .| .| .||.|||
--TTFCGTPWYMAPEVL-GYGKCKCDWWSCGCILYEMLC-GYPPFP------QMQMMFKKIG--------------SPEAKD-FIRKCLQKDPEKRPTA-
IHVS----NQILQFI
. ...
EALQDEWDIKCHPWF
|
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| Kinase | TVAG_207420.AA | CDK5 | 208-253 | 39 | 0.00059 | 7.85 | In-house | 181-225 (287) | Show / Hide |
Range on Protein: 208-253 Range on HMM: 181-225/287 Sequence Identity: 39% (18 aa) DCWSLGCLLAEYMIFAGPLFGSISINDQMVRTQMICGPAPAFLNWP | || || .|| . ||| . .||. | | | | .|| DMWSCGCIFAEMANAGRPLFPGNDVEDQLKRIFKIMG-TPCEDKWP |
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| Kinase | TVAG_207420.AA | YAK | 191-218 | 51 | 0.000647 | 8.75 | In-house | 169-197 (347) | Show / Hide |
Range on Protein: 191-218 Range on HMM: 169-197/347 Sequence Identity: 51% (15 aa) RFYRAPEWNANPMFCES-DCWSLGCLLAE |.||.|| .| | | ||||| .|| RHYRSPEIIVWMIYCTSIDMWSLGCIVAE |
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| Kinase | TVAG_207420.AA | HIPK | 191-218 | 58 | 0.000785 | 7.4 | In-house | 167-195 (329) | Show / Hide |
Range on Protein: 191-218 Range on HMM: 167-195/329 Sequence Identity: 58% (17 aa) RFYRAPEWNANPMFCES-DCWSLGCLLAE |.||||| |||. | ||||| .|| RYYRAPEIILGLPFCENHDMWSLGCVIAE |
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