97417.m00096

Species: T.vaginalis
Alias: TvagK0356, 97417.m00096
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
97417.m00096.AA Protein None 781 None Fasta, JSON
97417.m00096.kin_dom Protein Kinase Domain None 257 None Fasta, JSON

Protein domain

Protein domains of 97417.m00096.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 97417.m00096.AA TKL 200-450 26 2.7e-84 286.34 In-house 1-364 (364) Show / Hide
Range on Protein: 200-450
Range on HMM: 1-364/364
Sequence Identity: 26% (99 aa)

IGSGVSAVVYSGTYLP--------TGEAVAIKKLKFKKLTGPKL-------------------------QAFQRELAILATAIHPTVLKFIGATDFAP--
|||| ...|| |..          ||. ||.||.| .      .                         . . .|. ..    || ...|.|.    |  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------FSIVTEWMPGGSLYHDIHQNHRLDVTDQTIA-LFDIARGMRFLHS--------RSIIHRDLKTLNVLIDKNNR--------------A
            . ||.|..|||||.|..|        .|..    |||||| .|||        . |||||||. |.|.|.|..              .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KICDFGFSKQTEENQVMTMN--------------------IGTPHWMAPELLNVSQADQNA---------GQYNSKVDVYAYAIVMWEVLTHDLPYRGLE
||||||.|.  .... |...                    .||| |||||.|. .. ....         ..|. |.|||...||.||.||  .||... 
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

ATQII---------AQVLMNDARPAVP------------RGSPKAFVDLMKSCWARDPINRPSFAEIVRTF
  ..|         ..|  .  || .|               |. . .||. ||. || .|||| ||. ..
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase 97417.m00096.AA TKL-Unique 198-450 33 2.4e-73 250.01 In-house 3-290 (290) Show / Hide
Range on Protein: 198-450
Range on HMM: 3-290/290
Sequence Identity: 33% (100 aa)

NEIGSGVSAVVYSGTYLPTGEAVAIKKLKF-KKLTGPKLQAFQRELAILATAI-HPTVLKFIGATD----FAP-FSIVTEWMPGGSLYHDIH--------
| ||.|....|| |..   |. ||||....  ..   ..| | .|. .. .   || .....|..      .| ..||.| .||||||  .|        
NKIGEGGYGQVYKGKW--RGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

--QNHRLDVTDQTIALFDIARGMRFLHSRS--IIHRDLKTLNVLIDKN-----NRAKICDFGFSKQTEENQVMTMN----------IGTPHWMAPELLNV
  .|. |.   .     |||.|| .||...  |||||||..|.|.| |     ...||||||.||    .  || |          .|.. |||||.|. 
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

SQADQNAGQYNSKVDVYAYAIVMWEVLTHDL------PYRGLEATQIIAQVLM--NDARPAVPRGSPKAFVDLMKSCWARDPINRPSFAEIVRTF
.       ||. |.|||...||.|| .|...      ||.|.. .|... |       || .|   || . ||.. ||..|| .|||| ||.   
NF-----CQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL

Kinase 97417.m00096.AA MLK 194-450 32 2.9e-70 239.73 In-house 1-291 (291) Show / Hide
Range on Protein: 194-450
Range on HMM: 1-291/291
Sequence Identity: 32% (96 aa)

LQADNEIGSGVSAVVYSGTYLPTGEA-----VAIKKLKFKK----LTGPKLQAFQRELAILATAIHPT----VLKFIGATDFA-P-FSIVTEWMPGGSLY
.|    |||| . .|..|..   ..      ||.|. .. .     |.   ..|..|  .|.   ||     . .| |.     . | ||.|...|||||
IQFHEWIGSGSFGKVWKGRW--RNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLY

HDIHQ-NHRLD----------VTDQTIAL---FDIARGMRFLHSRS---IIHRDLKTLNVLID------KNNRAKICDFGFSKQTEEN-QVMTMNIGTPH
. .|  .   .          | |   |.   ...|||| .|||     |||||||  |.|||      ..  .|||||| |.   .. . |. |.||. 
NVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYA

WMAPELLNVSQADQNAGQYNSKVDVYAYAIVMWEVLTHDLPYR-GLEATQIIAQVLMNDARPAVPRGSPKAFVDLMKSCWARDPINRPSFAEIVRTF
||||| .        ...|. |.||. ...|.||.||  .||. .... .|...| .|  ||..| . |. .  ||| ||  || .||||..||  .
WMAPEVIQQ----FRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL

Kinase 97417.m00096.AA Dicty4 194-452 36 2.5e-69 230.39 In-house 1-277 (277) Show / Hide
Range on Protein: 194-452
Range on HMM: 1-277/277
Sequence Identity: 36% (104 aa)

LQADNEIGSGVSAVVYSGTYLPTGEAVAIKKLKFKKLT--GPKLQAFQRELAILATAIHPTVLKFIGATD---FAP--FSIVTEWMPGGSLYHDIHQ---
.. ...||.|  . || ||    | .||.|||. .. .     |..| .| .|..   || ...| ||      .|  ..|||| || |.||  .|    
INIEQRIGKGSFGEVYKGTW--RGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPS

----NHRLDVTDQTI---ALFDIARGMRFLHSRS--IIHRDLKTLNVLIDKNNRAKICDFGFSK----QTEENQ-VMTMNIGTPHWMAPELLNVSQADQN
    .  || .. .      ||.||||  ||..   |||||||. | |.|||.|.|.||||.|.     .. ..  ||. .||| ||||| . ..|.   
EQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTA-CGTPCWMAPEVM-MHQP---

AGQYNSKVDVYAYAIVMWEVLTHDLPYR--GLEATQIIAQVLMNDARPAVPRGSPKAFVDLMKSCWARDPINRPSFAEIVRT--FRT
   ||.|.||| ..|| || || . ||   . .  |... |     || .|   |. . .|.. ||  ||..||||.||.      .
---YNEKADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH

Kinase 97417.m00096.AA Pkinase 194-450 26 1.3e-62 219.07 Pfam 1-293 (293) Show / Hide
Range on Protein: 194-450
Range on HMM: 1-293/293
Sequence Identity: 26% (81 aa)

LQADNEIGSGVSAVVYSGTYLPTGEAVAIKKLKFKKLTGPKLQAFQR--ELAILATAIHPTVLKFIGAT-DFAPFSIVTEWMPGG----SLYHDIH--QN
..    |||| ...|| ..   ||. ||.|..| ..    |.|.  |  |..|..   || .......  |     .|.|...||    .|.. |.  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

HRL--DVTDQTIALFDIARGMRFLHSRSIIHRDLKTLNVLIDKNNRA----KICDFGFSKQ--TEENQVMTMNIGTPHWMAPELLNVSQADQNAGQYNSK
 ..  .  .    .  |.||. ..||..|||||||  |.|||.|.      ||||||..||  .  |. ||   |||..||||...       .  | .|
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR------GGQYYGPK

VDVYAYAIVMWEVLTHDLPYRGL------EATQIIAQVLMNDARPAVPRGSP-------------------KAFVDLMKSCWARDPINRPSFAEIVRT--
||.... ....|.|.  .|..|       .  |.|..... . .   |  ..                   ... |..|.|...||  ||....|.    
VDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPW

F
|
F

Kinase 97417.m00096.AA Dicty4-Unclassified 194-450 34 1.9e-60 205.7 In-house 1-263 (263) Show / Hide
Range on Protein: 194-450
Range on HMM: 1-263/263
Sequence Identity: 34% (94 aa)

LQADNEIGSGVSAVVYSGTYLPTGEAVAIKKLKFKKLTGP--KLQAFQRELAILATAIHPTVLKFIGATDFAP------FSIVTEWMPGGSLYHDIH---
.| | .|| |  . |. |     |  ||.||.   |       .| | .| .||    ||  .|  |.   .|      . ||.| |. | |   ||   
IQIDQFIGKGHFSKVHKGNW--KGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYC-INPRSHKSTMCIVMEFMHKGNLFEVIHSKP

--QNHRLDVTD---QTIALFDIARGMRFLHSRSIIHRDLKTLNVLIDKNNRAKICDFGFSKQTEENQVMTMNIGTPHWMAPELLNVSQADQNAGQYNSKV
  |.  .   |     .| ||||.|| .||.| .||||.|  |.|.||.. .|| ||| |  .. |. ||   ||| | .|| |           ||.| 
SEQQQPIKLDDTLIIKYA-FDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECL-------MHESYNQKS

DVYAYAIVMWEVLTHDLPYRGLE-ATQIIAQVLMNDARPAVPRGSPKAFVDLMKSCWARDPINRPSFAEIVRTF
||| ||....| .| | || .      .   |     || .|   .  .  | | ||  ||  ||.. .|.   
DVYSYAMMLYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL

Kinase 97417.m00096.AA Pkinase_Tyr 194-450 29 1.2e-59 202.67 Pfam 1-270 (270) Show / Hide
Range on Protein: 194-450
Range on HMM: 1-270/270
Sequence Identity: 29% (83 aa)

LQADNEIGSGVSAVVYSGTYL----PTGEAVAIKKLKFKKLTGPK---LQAFQRELAILATA-IHPTVLKFIGA-T-DFAP--FSIVTEWMPGGSLYHDI
.. . ..|.|   .|| ||.      |.  ||.|.|  |  . ..   ...| ||..|. .   || .....|. | .  |    ||.| ||.|.|..  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML--KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

HQ----NHRLDVTDQTIALFDIARGMRFLHSRSIIHRDLKTLNVLIDKNNRAKICDFGFSKQT---EEN-QVMTMNIGTPHWMAPELLNVSQADQNAGQY
..    ...|.. |     ..||.|| .|.|. .||||| . |.|...|| .|||||| ..     ..  .. .       ||||| .| .        .
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK-------F

NSKVDVYAYAIVMWEVLT-HDLP-YRGLEATQIIAQVLMNDARPAVPRGSPKAFVDLMKSCWARDPINRPSFAEIVRTF
..| ||... ..|||..|  . | | |.  .......  .  | . |.. |.   ||||.||. || .||.|.||.. .
TTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL

Kinase 97417.m00096.AA S_TKc 194-452 25 1.9e-59 204.74 SMART 1-231 (231) Show / Hide
Range on Protein: 194-452
Range on HMM: 1-231/231
Sequence Identity: 25% (69 aa)

LQADNEIGSGVSAVVYSGTYLPTGEAVAIKKLKFKKLTGPKLQAFQRELAILATAIHPTVLKFIGATDFAPFSIVTEWMPG--GSLYHDIHQNHR-----
 .  ..||.|  ..|| ..   ||. ||||..|         . ..||..||    || . |.... .   . .|.| ..|  |.|.. |... |     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LDVTDQTIALFDIARGMRFLHSRSIIHRDLKTLNVLIDKNNRAKICDFGFSKQTEENQVMTMNIGTPHWMAPELLNVSQADQNAGQYNS-KVDVYAYAI
 ..  .    .  |.... ..||. |||||||  |.|.|.  . ||||||...|       |  .|||..||||.|          .|.  |.|...  .
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL----------GYGKCKCDWWSCGC

VMWEVLTHDLPYRGLEATQIIAQVLMNDARPAVPRGSPKAFVDLMKSCWARDPINRPSFAEIVR-------TFRT
...| |.   |..     | . ....           .. . |... |. .|| .||.  |. .           
ILYEMLCGYPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 97417.m00096.AA Dicty5 194-454 35 8.3e-59 201.04 In-house 1-260 (260) Show / Hide
Range on Protein: 194-454
Range on HMM: 1-260/260
Sequence Identity: 35% (96 aa)

LQADNEIGSGVSAVVYSGTYLPTGEAVAIKKLKFKKLTGPKLQAFQRELAILATAI--HPTVLKFIGATDFAPFS--IVTEWMPGGSLYHDIHQNHR---
      | || |  ||.| |   |  |||| .      .  .. |.|| .|.      || . .. ||         .|||    |||     .  .   
VSFHDWIASGASGRVYNGIY--KGMDVAIKVYSQENCMCFDWNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTG

--LDVTDQTIALFDIARGMRFLHSRSIIHRDLKTLNVLIDKNNRAKICDFGFSKQTEENQVMTMNIGTPHWMAPELLNVSQADQNAGQYNSKVDVYAYAI
  .    |     |||..||.||| .||||||| .|.|| .|  .|| ||| |   .    |||..||. |||.|| | .|       |  |.|||...|
QPIAYFQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFN-GQP------YHQKCDVYSFGI

VMWEVLTHDLPYRGLEATQI-IAQVLMNDARPAVPRGSPKAFVDLMKSCWARDPINRPSFAEIVRTFRTGE
| ||..| . ||   . ... |.   |   || .|   |  .  | |.||   | ||||| ||. .|.   
VLWEMFTRKEPYD--NINNWNIPVMVMKGERPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII

Kinase 97417.m00096.AA LRRK 194-452 24 1.7e-58 200.63 In-house 1-351 (351) Show / Hide
Range on Protein: 194-452
Range on HMM: 1-351/351
Sequence Identity: 24% (87 aa)

LQADNEIGSGVSA-VVYSGTYL--------------------------PTGEAVAIKKLKFK---------KLTG-----------------------PK
|   ..||.|... .|| ...                             .. |||||...            ..                        .
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

LQAFQRELAILATAIHPTVLKFIGATDFAPFSIVTEWMPGGSLYHDIHQNHRLD------V----TDQTIALFDIARGMRFLHSRS--IIHRDLKTLNVL
.. |..|..|. .  || ... .| . . |. .|.| .| |.||| .| ...        .    . . ||| .||.||..|||..  |||||||. |.|
FREFRHEVWIMSHLNHPNIVSLKGFC-IHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIAL-QIAKGMEYLHSHNPPIIHRDLKSPNIL

I--DKNN----------RAKICDFGFSK--QTEENQVMTMNIGTPHWMAPELLNVSQADQNAG---QYNSKVDVYAYAIVMWEVLTHD-LPYRGLE-A--
.   ..|           |||.||| |   |.  . |     |.| ||||| ..       ..   .|. |||.|......|| || . .|.....    
LWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMR-------YNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDH

---TQIIAQVLMNDARPAVP---RGS---PKAFVDLMKSCWARDPINRPSFAEIVRTFRT
   . .| .  ..  || .|   ..    .  . ||...||. || .||.| .|| .  .
MQWMEQIEDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ

Kinase 97417.m00096.AA TyrKc 194-450 28 1.1e-57 198.83 SMART 1-280 (280) Show / Hide
Range on Protein: 194-450
Range on HMM: 1-280/280
Sequence Identity: 28% (85 aa)

LQADNEIGSGVSAVVYSGTYLPTGEAVAIKKLKFKKLTGPKLQAFQRELAILATA--IHPTVLKFIG-ATDF-------APFSIVTEWMPGGSLYHDIHQ
.. . ..|.|   .|| ||.    . ||.|.||  .     ...| ||. |.      || .....| .|.         |  ||.| ||.|.| . .. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

NHR-LDVTDQTIALFDIARGMRFLHSRSIIHRDLKTLNVLIDKNNRAKICDFGFSKQTEEN-------QVMTMN--IGTP-----HWMAPELLNVSQADQ
... | . |     ..||.||..|||. .||||| . |.|...|...||.||| |.  ..        .. ..    |.       ||||| .       
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-------

NAGQYNSKVDVYAYAIVMWEVLTH-DLPYRG-----LEATQIIAQVLMNDARPAVPRG-------SPKAFVDLMKSCWARDPINRPSFAEIVRTF
| | ...| ||... ..|||..|  . || |     ......|..|   . .|  | .        |..  ..||.||..|| .||.|.||.. |
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase 97417.m00096.AA TK 194-450 15 2.4e-55 183.62 In-house 1-486 (486) Show / Hide
Range on Protein: 194-450
Range on HMM: 1-486/486
Sequence Identity: 15% (76 aa)

LQADNEIGSGVSA---VVYSGTYLPTG-------------------------EAVAIKKLKFKKLTGPK-LQA--------------FQRELAILAT-AI
..  ...|.|      .|| |.. . .                         . ||.| || .  . ..  ..              . .|....   . 
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPTVLKFIGATDFA-------------PFSIVTEWMPGGS----LYHDIHQNHR---------------------------------------------
 || .....|.                 |. ||.|.||.|.    | .  .....                                             
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LDVTDQTIALFDIARGMRFLHSR------SIIHRDLKTLNVLIDKNNR-----------AKICDFG---
                               |.. ..    ..||.||..|||.       ..|||| . |.|...||.           .||.|||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----FSKQTEENQVMTMNIGTPH---------------------------WMAPELLNVSQADQN--AGQYNSKVDVYAYAIVMWEVLTHD-LPYRGLE
      ..  ....  .   .  .                           ||||| ||  .  .    | . .| ||... ..|||..|.   || |  
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

AT---------QIIAQVLMND--------------ARPAVPRGSP--------------KAFVDLMKSCWARDPINRPSFAEIVRTF
           | . . | .                |.. | . |              ... |||..||..||  ||.|..... .
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase 97417.m00096.AA DRK 194-452 35 1.3e-53 179.93 In-house 1-258 (258) Show / Hide
Range on Protein: 194-452
Range on HMM: 1-258/258
Sequence Identity: 35% (95 aa)

LQADNEIGSGVSAVVYSGTYLPTGEAVAIKKLKFKKLT-GPKLQAFQRELAILATAIHPTVLKFIGATDFAP-FSIVTEWMPGGSLYHDIHQNH-RLDVT
    | || |  . |. ||    |  ||.|.|.         |. |.||  ..    || .  |.|.    |   |..| || ||||   |     .|  
IKIGNRIGRGNYGEVFRGTW--RGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWP

DQTIALFDIARGMRFLHSRS--IIHRDLKTLNVLIDKNNRAKICDFGFSK----QTEENQVMTMNIGTPHWMAPELLNVSQADQNAGQYNSKVDVYAYAI
      ||.|.|| .||..   |||||||. | |.| . . |. ||| |       .    ||| .||| | ||| |    ..|    |  | ||| .||
LMKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTM-CGTPCWTAPEVL----RNQ---RYTEKADVYSFAI

VMWEVLTHDLPYRGLEATQIIAQVLMNDARPAVPRGSPKAFVDLMKSCWARDPINRPSFAEIVRTFRT
| ||..|   || |    |..  |     || .|   |  .. ||. ||  ||  |||. |..     
VLWECVTRQDPYFGMPTFQVVFSVGRHGMRPPMPQWCPPKYIQLMNDCWNEDPQHRPSMQECLERLEA

Kinase 97417.m00096.AA HH498 194-450 28 1.4e-52 164.77 In-house 1-284 (284) Show / Hide
Range on Protein: 194-450
Range on HMM: 1-284/284
Sequence Identity: 28% (84 aa)

LQADNEIGSGVSAVVYSGTYLPTGEAVAIKKLKFKK-LTGPK-----LQAFQRELAILATAIHPTVLKFIGAT--DFAPFSIVTEWMPGGSLYHDI----
.     ||||    || |..   .  ||.|  . .. .   .        | ||  |.    || | .|..|.  |   | |||..  .|||.       
IEFHEKIGSGSFGKVYKGEW--RNKIVAVKRYRAMAFCCKSDSYQWIVDMFCREVSIMCRLNHPCVVQFVYACCDDPSQFAIVTQYCDNGSLFSILNTIP

----------HQNH----RLDVTDQTIALFDIARGMRFLHS---RSIIHRDLKTLNVLIDKNNRAKICDFGFS--KQTEENQVMTMNIGTPHWMAPELLN
          |..      .|     .   |.|.||..||.   . ||||||   |.||... .|.. ||| |  ..  .   ||  .| . |||||   
IGGAGANNNNHNQKNNYRIMDLQSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDGHAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEVFS

VSQADQNAGQYNSKVDVYAYAIVMWEVLTHDLPYRGLEATQIIAQVLMNDARPAVPRG----SPKAFVDLMKSCWARDPINRPSFAEIVRTF
 .|      .|  ||||. ||...|| .|  .|.  ..     | .     || .|       |.  . |.  ||   | |||.|..||.  
QCQ------KYSIKVDVFSYAMCIWEMHTREVPFHHYKPAAAAAEMAYHHIRPPIPQTPTAQIPHHWSNLIQMCWHPCPENRPDFDQIVTIL