Gene 95227.m00063 (T.vaginalis)

95227.m00063

Species: T.vaginalis
Alias: TvagK0342, 95227.m00063
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
95227.m00063.AA Protein None 912 None Fasta, JSON
95227.m00063.kin_dom Protein Kinase Domain None 240 None Fasta, JSON

Protein domain

Protein domains of 95227.m00063.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 95227.m00063.AA TKL 193-426 23 4.2e-72 245.86 In-house 1-364 (364) Show / Hide 
Range on Protein: 193-426
Range on HMM: 1-364/364
Sequence Identity: 23% (87 aa)

IGSGTFSTIFQGRRKSTN--------EEVAIKFFTSAH--SRTE-----------------------HFNQLICEANAYSRLNHKNIVKFHGVTKEPP--
||||.|.....|. . ..        ..||.| | | .  ..|.                        . ... |..  |||.| |||.| |. ..||  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------FMLITEFMDGGSLFRGLQTPGALDAPEMLDHIALSIANGLVYLHKLG--------SIHGDIKSLNILLSKSGG--------------V
            .....|...||||.  |.       .. . ..||.|| |. |||  .         || |.|| |||. . .               .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KLCDFGSSRVFHDPN--------------------ADIGPIGTISWSAPEMLRTE-------------GERMISPAADVYSYGVVLLEMATRRPPESNN-
|.|||| ||...  .                    . . ..||. | |||.|| .             ...  |...||||.|.|| |..||..|.... 
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

----------------------RKVVP------------PDTPPKLRSLIEKCLSADPFMRPTMSEIVQMF
                      |  .|            ||.|| ...|...| ..||  ||...||.. .
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
S_TKc 95227.m00063.AA S_TKc 187-431 28 4.1e-52 180.38 SMART 1-231 (231) Show / Hide 
Range on Protein: 187-431
Range on HMM: 1-231/231
Sequence Identity: 28% (74 aa)

LEILKKIGSGTFSTIFQGRRKSTNEEVAIKFFTSAHSRTEHFNQLICEANAYSRLNHKNIVKFHGVTKEPPFMLITEFMDG--GSLFRGLQTPGAL----
 |||.|||.|.|.. ...| |.|...||||            .... | .  .. .|.||||...|  .  . ...|..||  |.||. ..  |      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-DAPEMLDHIALSIANGLVYLHKLGSIHGDIKSLNILLSKSGGVKLCDFGSSRVFHDPNADIGPIGTISWSAPEMLRTEGERMISP-AADVYSYGVVLLE
   . .  ...  |...| |.|..| || |.|  ||||..   .|.||||..|..         .||  . |||.|        .. ..|..| |..| |
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL------GYGKCKCDWWSCGCILYE

MATRRP----PESNNRKVVPPDTPPKLRSLIEKCLSADPFMRPTMSEIVQ----MFEQKLI
|....|    ..   .|..    .| ....|.|||  ||  |||  |. |          .
MLCGYPPFPQMQMMFKKIG----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase 95227.m00063.AA Pkinase 187-385 30 7e-49 173.5 Pfam 1-211 (293) Show / Hide 
Range on Protein: 187-385
Range on HMM: 1-211/293
Sequence Identity: 30% (66 aa)

LEILKKIGSGTFSTIFQGRRKSTNEEVAIKFFTSAHSRTEHFNQLIC--EANAYSRLNHKNIVKFHGVTKEPPFML-ITEFMDGG----SLFRGLQ--TP
..|..|||||.|.. .....|.|...||.| .   | . .   ...   |.    ||||.|||.....  ... .  ..|...||    .||. ..    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GAL--DAPEMLDHIALSIANGLVYLHKLGSIHGDIKSLNILLSKSGGV----KLCDFGSSRVF-HDPNADIGPI-GTISWSAPEMLRTEGERMISPAADV
|..  .  |   .... |. || |.|. | || |.|. |||... | .    |.||||....| . .|     . ||. . ||| .|  | ....|..|.
GCFYFSEWECK-FYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR--GGQYYGPKVDM

YSYGVVLLEMATRRPP
.|.|..| ||...|||
WSCGCILYEMLCGRPP
Kinase 95227.m00063.AA TK 187-426 14 4.8e-48 158.71 In-house 1-486 (486) Show / Hide 
Range on Protein: 187-426
Range on HMM: 1-486/486
Sequence Identity: 14% (72 aa)

LEILKKIGSGTFS---TIFQGRRKSTN-------------------------EEVAIKFFT--SAHSRTEHFN-------------QLICEANAYS--RL
....||.|.| |    ....|. .. |                         ..||.|  .  .|.| .|.|              ..  |.   .   .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

NHKNIVKFHG-VTKE------------PPFMLITEFMDGGS----LFRGLQ--TPGALDAPEMLDH----------------------------------
.|.|||...| .|..            .|.|...|.|..|.    |   |.   |.. . ..  |.                                  
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

--------------------------------------IALSIANGLVYLHKL------GSIHGDIKSLNILLSKSGG-----------VKLCDFG----
                                      ... ||.|. |||..      . .|.|.   |.|.....            .|..|||    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

----SSRVF-HDPNADIGPIGTIS--------------------------WSAPEMLRTEG------ERMISPAADVYSYGVVLLEMAT---RRPP--ES
     .|   .| .      .. .                          | ||| |..        ..  ... ||.|.||.. |. |     ..   |
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS

N---------------------------------NRKVVPPDTP--------------PKLRSLIEKCLSADPFMRPTMSEIVQMF
|                                 .|.  ||. |              . .  |. .| ..||  |||.|......
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase 95227.m00063.AA STE 187-421 23 2e-47 163.85 In-house 1-350 (359) Show / Hide 
Range on Protein: 187-421
Range on HMM: 1-350/359
Sequence Identity: 23% (85 aa)

LEILKKIGSGTFSTIFQGRRK------STNEE---------VAIKFFTSAHSRT---------------EHFNQLICEANAYSRLN--HKNIVKFHGVTK
.|...|||.|.| | ......      .|.|.         .|||     ....               | ..|.. | .  ...|  |.||||..|   
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

--------EPPFMLITEFMDGGSLFRGLQ-TPGALDA------------PEMLDHIALSIANG-LVYLHKLGSIHGDIKSLNILLSKSGGVKLCDFGSSR
        .    .. |.||||||   .. . | ..              . . .|. .|  | | |||... || |||. ||||     ||||||| . 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

VFHDPNA------------DIG-----PIGTISWSAPEMLRTEG---ERMISPAADVYSYGVVLLEMATRRPPE---SNNR-------------------
 . | .|            ...      .||  | |||... .|   .   .  .|..| | ...|||| .||    .. |                   
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---KVVPPDTP----------------------PKLRSLIEKCLSADPFMRPTMSE
   .  ||  .                      |...  |.|||  ||  ||| |.
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQ
Kinase 95227.m00063.AA MLK 187-385 30 1.9e-41 141.55 In-house 1-235 (291) Show / Hide 
Range on Protein: 187-385
Range on HMM: 1-235/291
Sequence Identity: 30% (71 aa)

LEILKKIGSGTFSTIFQGRRKSTN---EEVAIKFFT-------SAHSRTEHFNQLICEANAYSRLN-HKNIVKFHGVTKEP-P-FMLITEFMDGGSLFRG
......||||.|   . || . ..    .||.| ..       .. .  ..|.. . ...  |..| | .|..| || ..| . | ...|...||||.. 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

L--QTPGALDA-----------PEMLDHIALSIANGLVYLHKLGS---IHGDIKSLNILLS------KSGGVKLCDFGSSRVFHDPNA-DIGPIGTISWS
|  ....  ||           .. .  .|| .|.|. |||..     || |.|| |||..      . | .| |||| || .|.  .   . .||  | 
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWM

APEMLRTEGERMISPAADVYSYGVVLLEMATRRPP
|||..    . . | ..||.|.|||| || ||. |
APEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP
Kinase 95227.m00063.AA TKL-Unique 189-382 29 9.7e-41 141.41 In-house 1-224 (290) Show / Hide 
Range on Protein: 189-382
Range on HMM: 1-224/290
Sequence Identity: 29% (68 aa)

ILKKIGSGTFSTIFQGRRKSTNEEVAIKFFT-SAHSRTEHFNQLICEANAYSRLN-HKNIVKFHGVTK----EPP-FMLITEFMDGGSLFRGLQ------
...|||.|.......|  ...  .|||| |   . |. |    .. | |  ..|. |.|||.. |...     || . ...|...||||   |.      
FWNKIGEGGYGQVYKGKWRGY--PVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

---TPGALDAPEMLDHIALSIANGLVYLHKLG--SIHGDIKSLNILLSKS-----GGVKLCDFGSSRVFH----DPNADI------GPIGTISWSAPEML
    .     ...  ..|. || |. ||| ..   ||.|.||.|.|..         .|.|||| |..       .|  .      ...|.. |.|||.|
NNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

RTEGERMISPAADVYSYGVVLLEMATR
| .   ..|  .||||.|.|| |.|||
RMNF-CQYSEKSDVYSFGIVLWEIATR
Kinase 95227.m00063.AA LISK 192-426 27 8.7e-37 116.92 In-house 1-296 (296) Show / Hide 
Range on Protein: 192-426
Range on HMM: 1-296/296
Sequence Identity: 27% (81 aa)

KIGSGTFSTIFQGRRKSTNEEVAIKFFTS---AHSRTEHFNQLICEANAYSRLNHKNIVKFHGVTKE--PPFMLITEFMDGGSLFRGLQ-TPG---ALDA
.||.| |. ...|. . |....|||  ..      . | .  .. |     .| |.|||.| || ..    ....||...|| |.. |  ..     |  
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPLPW

PEMLDHIALSIANGLVYLHKLGSIHGDIKSLNILLSKS----GGVKLCDFGSSRVFHDPN------------------------------ADIGP-----
|. . .||| || |. |||  . || | || |.|....      .|.||||  |.. ..|                              .. ..     
PQRV-KIALDIACGMSYLHSMNIIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMPMKRKIPKKCMNQRKRRMTI

IGTISWSAPEMLRTEGERMISPAADVYSYGVVLLEMATRRPPES-----NN-----------RKVVPPD-TPPKLRSLIEKCLSADPFMRPTMSEIVQMF
 || .| |||||.    .  . ..||.|.|.||.|. ||. .       ..           .. ..||  || .  |  .| . || .||. .|||| .
CGTPYWMAPEMLL---GQSYDESCDVFSFGIVLCEIITRVKADPDYWPRTPQHDFGLDYEEFWQKICPDDCPPPFLDLCFDCCKYDPKNRPSFKEIVQWL
Kinase 95227.m00063.AA Dicty4-Unclassified 187-381 34 4.2e-35 117.63 In-house 1-203 (263) Show / Hide 
Range on Protein: 187-381
Range on HMM: 1-203/263
Sequence Identity: 34% (72 aa)

LEILKKIGSGTFSTIFQGRRKSTNEEVAIKFF--TSAHSRTEHFNQLICEANAYSRLNHKNIVKFHGVTKEP-----PFMLITEFMDGGSLFRGLQ-TPG
. |.. || | || .  |  |    .||.| |   .   | |       |      . | | ||  |    |      .. ..|||  | ||      | 
IQIDQFIGKGHFSKVHKGNWKG--KDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPS

ALDAPEMLDH-----IALSIANGLVYLHKLGSIHGDIKSLNILLSKSGGVKLCDFGSSRVFHDPNADIGPIG-TISWSAPEMLRTEGERMISPAADVYSY
  . |  ||      .|..|| |. .||    || |||| |||. |   .|  ||| |||  | |     |. |  | .|| |. |       ..|||||
EQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVI-DFNFNMTTIAGTPKWESPECLMHE---SYNQKSDVYSY

GVVLLEMAT
...| |.||
AMMLYELAT
Kinase 95227.m00063.AA TyrKc 187-426 25 6.3e-29 103.35 SMART 1-280 (280) Show / Hide 
Range on Protein: 187-426
Range on HMM: 1-280/280
Sequence Identity: 25% (75 aa)

LEILKKIGSGTFSTIFQGRRKSTNEEVAIKFFTSAHSRTEHFNQLICEANAYSRL--NHKNIVKFHGVTKE--------PPFMLITEFMDGGSLFRGLQT
.. .||.|.| | ....|. |   ..||.|   . .        .. ||.  ..|  .|.|||...||  .        .| |...|.|..|.|   |. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

PGALDAPEMLDHIALSIANGLVYLHKLGSIHGDIKSLNILLSKSGGVKLCDFGSSRVFHDP-------NADI-----GPI--GTISWSAPEMLRTEGERM
..    .. | .... ||.|  |||. . || |.   |.|... . || .||| ||  .|                 |      | | ||| .    ...
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI---NYGK

ISPAADVYSYGVVLLEMATR--RPPES------NNRKVV-----------PPD--------TPPKLRSLIEKCLSADPFMRPTMSEIVQMF
 ... ||.|.||.. |. |.   |..       .|. |.           ||.         |... .....|  .|| .|||.|||.. |
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 95227.m00063.AA Pkinase_Tyr 187-329 28 2.5e-28 96.54 Pfam 1-156 (270) Show / Hide 
Range on Protein: 187-329
Range on HMM: 1-156/270
Sequence Identity: 28% (45 aa)

LEILKKIGSGTFSTIFQGRRK----STNEEVAIKFFTSAHSRTEH--FNQLICEANAYSRL-NHKNIVKFHGVTK--EPP--FMLITEFMDGGSLFRGLQ
....||.|.| | ....|. |    .|. .||.|     ..  |.     .. ||.  . | .|.|||...||    . |   ....|.| .|.|   |.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

T----PGALDAPEMLDHIALSIANGLVYLHKLGSIHGDIKSLNILLSKSGGVKLCDFG
.    ...|. .. | .... ||.|. ||.  . || |.   |.|..... || ||||
KHREDKQPLTMKD-LLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase 95227.m00063.AA Dicty4 187-382 31 5.4e-26 83.81 In-house 1-213 (277) Show / Hide 
Range on Protein: 187-382
Range on HMM: 1-213/277
Sequence Identity: 31% (68 aa)

LEILKKIGSGTFSTIFQGRRKSTNEEVAIKFF--TSAHSRTEHFNQLICEANAYSRLNHKNIVKFHGVTK----EPPFMLI-TEFMDGGSLFRGLQT---
. | ..||.| |.. . |. . .  |||.| .  .   .. .  | .  |..  . . | ||..| |       .|. |.| ||.|  |.|.. |     
INIEQRIGKGSFGEVYKGTWRGK--EVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPS

----PGALDAPEMLD--HIALSIANGLVYLHK--LGSIHGDIKSLNILLSKSGGVKLCDFGSSRVF--HDPNAD--IGPIGTISWSAPEMLRTEGERMIS
       || | ..    .|...| |. .||      || |.|| |.| .|.  || |||| |...  |  . |   ...||  | |||... ..     
EQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQP---YN

PAADVYSYGVVLLEMATR
 .|||||.| || |..||
EKADVYSFGIVLWEILTR
Kinase 95227.m00063.AA LRRK 187-385 24 1.6e-25 87.21 In-house 1-282 (351) Show / Hide 
Range on Protein: 187-385
Range on HMM: 1-282/351
Sequence Identity: 24% (68 aa)

LEILKKIGSGTFS-TIFQGRRKS-------------TN-------------EEVAIKFFTS--------------------------------AHSRTEH
|.| ..||.|.|  ...... ..              .             ..|||| ..                                 . .... 
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

FNQLICEANAYSRLNHKNIVKFHGVTKEPPFMLITEFMDGGSLFRGLQTPG--AL-----D-APEMLDHIALSIANGLVYLHKLG--SIHGDIKSLNILL
|. .  |.   |.||| |||.  |.. . |.....|... |.| . |. .   ..     .  . ..  ||| || |. |||.     || | || ||||
FREFRHEVWIMSHLNHPNIVSLKGFCIH-PLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILL

SKSG------------GVKLCDFGSSR-VFHDPNA-DIGPIGTISWSAPEMLRTEGERMISPAADVYSYGVVLLEMATRR-PP
 .|              .|..||| ||  . ....   |  |.. | ||| .| .||   .  .|.||.|..| |  ||. .|
WSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHP
Kinase 95227.m00063.AA STE20 296-385 35 1.1e-19 68.79 In-house 129-226 (288) Show / Hide 
Range on Protein: 296-385
Range on HMM: 129-226/288
Sequence Identity: 35% (35 aa)

GLVYLHKLGSIHGDIKSLNILLSKSGGVKLCDFGSSRVFHD----PNA-D-IGPIGTISWSAPEMLRTEG--ERMISPAADVYSYGVVLLEMATRRPP
|| |||. . || |||. ||||...| |||.||| .  . .     ..      .||  | |||... ..  .      .|..| |  ..|||...||
GLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGPDKGYDYKCDIWSLGITAIEMAEGEPP
Kinase 95227.m00063.AA Dicty4 393-428 36 9.6e-14 42.39 In-house 240-277 (277) Show / Hide 
Range on Protein: 393-428
Range on HMM: 240-277/277
Sequence Identity: 36% (14 aa)

VPPDTPPKLRSLIEKCLSADPFMRPTMSEIVQM--FEQ
.|...||....||..|.. ||  ||...||.|    | 
IPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase 95227.m00063.AA STE20 187-270 27 1.3e-13 46.35 In-house 1-95 (288) Show / Hide 
Range on Protein: 187-270
Range on HMM: 1-95/288
Sequence Identity: 27% (26 aa)

LEILKKIGSGTFSTIFQGRRKSTNEE----VAIKFFTSAHS---RTEHFNQLICEANAYSRLNHKNIVKFHGV-TKEPPF----MLITEFMDGGSL
 |.|.|||.|.. ... .. |.|.|.    ||||     .    . .... .. | .  ....|.||||..|   |. .      .. |...||||
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQ-DEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSL
Kinase 95227.m00063.AA LRRK 392-428 32 1.5e-09 29.97 In-house 309-351 (351) Show / Hide 
Range on Protein: 392-428
Range on HMM: 309-351/351
Sequence Identity: 32% (14 aa)

VVPPD-TPP-----KLRSLIEKCLSADPFMRPTMSEIVQMFEQ
..|..  ||      . .||..| ..||  ||..|.||.  .|
TIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase 95227.m00063.AA MLK 393-426 32 6.4e-09 27.21 In-house 258-291 (291) Show / Hide 
Range on Protein: 393-426
Range on HMM: 258-291/291
Sequence Identity: 32% (11 aa)

VPPDTPPKLRSLIEKCLSADPFMRPTMSEIVQMF
.|.. |. . .|...| ..||  ||....||| .
IPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase 95227.m00063.AA Pkinase_Tyr 394-426 36 1.3e-07 26.44 Pfam 238-270 (270) Show / Hide 
Range on Protein: 394-426
Range on HMM: 238-270/270
Sequence Identity: 36% (12 aa)

PPDTPPKLRSLIEKCLSADPFMRPTMSEIVQMF
|...|... .|. .|  .|| .|||.|||....
PENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase 95227.m00063.AA Dicty4-Unclassified 393-426 35 2e-07 21.45 In-house 230-263 (263) Show / Hide 
Range on Protein: 393-426
Range on HMM: 230-263/263
Sequence Identity: 35% (12 aa)

VPPDTPPKLRSLIEKCLSADPFMRPTMSEIVQMF
.|   .. ...||  |.. ||  |||| .|.|  
IPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase 95227.m00063.AA TKL-Unique 393-426 35 2e-06 18.54 In-house 257-290 (290) Show / Hide 
Range on Protein: 393-426
Range on HMM: 257-290/290
Sequence Identity: 35% (12 aa)

VPPDTPPKLRSLIEKCLSADPFMRPTMSEIVQMF
.|.. |. .| ||..|   ||  ||. .||.   
IPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase 95227.m00063.AA Pkinase 390-426 28 3.6e-05 19.37 Pfam 256-293 (293) Show / Hide 
Range on Protein: 390-426
Range on HMM: 256-293/293
Sequence Identity: 28% (11 aa)

RKVVPPDTPPKLRSLIEKCLSADPFMRPTMSEIVQM--F
.... . ... ....|..||  ||  |||  .|.|   |
HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 95227.m00063.AA Pkinase_Tyr 349-382 32 0.058467 7.26 Pfam 180-210 (270) Show / Hide 
Range on Protein: 349-382
Range on HMM: 180-210/270
Sequence Identity: 32% (11 aa)

WSAPEMLRTEGERMISPAADVYSYGVVLLEMATR
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WMAPECINYGK---FTTKSDVWSFGVLMWEIFTY