94444.m00175

Species: T.vaginalis
Alias: TvagK0338, 94444.m00175
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
94444.m00175.AA Protein None 793 None Fasta, JSON
94444.m00175.kin_dom Protein Kinase Domain None 250 None Fasta, JSON

Protein domain

Protein domains of 94444.m00175.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 94444.m00175.AA TKL 214-457 30 2.1e-96 326.55 In-house 1-364 (364) Show / Hide
Range on Protein: 214-457
Range on HMM: 1-364/364
Sequence Identity: 30% (111 aa)

IGEGASSTVYKGFFKH---------DKQVAIKKLKYH--KLKGGKLRV---------------------FQREVSILASAE--HPCLVHFVGATDTAP--
||.|....|||| ..          .| ||.||.| |  ...  ...                      |..|. |.      || .|.|.|.    |  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------FCIVTEWINGGSLYALLRTKKPISASKKTSIAFDIARGMNYLHSRH--------IIHRDLKSPNVLLDDNGR--------------AK
            .|||.|.. ||||. .|        ... ..| |||||||||||..        ||||||||.|.|.|.|..              .|
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

ICDFGYSRVADDTDVMTKN--------------------VGTPHWMAPELLDNQ---------------SSYNHMIDVYSYGIVLWEITAQAVPYRDLDS
||||| ||. . .  |...                    .||| |||||.|..|               ..|.  .||||.||||||| .  .||.|...
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPY

PQII---------AKVVSSDFRPPIP------------EGTHPDIVNLIKQCWDRDPNQRPTFSEILNRF
...|         ..|..   |||||            . . |.. .|...||| ||..||.|.||| |.
MPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase 94444.m00175.AA MLK 208-457 32 3.3e-85 289.37 In-house 1-291 (291) Show / Hide
Range on Protein: 208-457
Range on HMM: 1-291/291
Sequence Identity: 32% (96 aa)

LEEKQQIGEGASSTVYKGFFKHDK----QVAIKKLKYHK----LKGGKLRVFQREVSILASAEHPC----LVHFVGA-TDTAP-FCIVTEWINGGSLYAL
..... ||.|..  |.|| ..        ||.|. .  .     ..   . |..|. .|.   ||      . |.|. ... . ||||.|.. ||||| .
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LRTKKP--------------ISASKKTSIAFDIARGMNYLHSRH---IIHRDLKSPNVLLDD------NGRAKICDFGYSRVADDT-DVMTKNVGTPHWM
|.....              .. . . ..|...||||.||||     ||||||||.|.|.|.      .| .|||||| ||   .. . |..| ||. ||
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWM

APELLD--NQSSYNHMIDVYSYGIVLWEITAQAVPYR-DLDSPQIIAKVVSSDFRPPIPEGTHPDIVNLIKQCWDRDPNQRPTFSEILNRF
||| .     . |.   ||.|.|.||||. .  |||. ..|. .|...|.    ||||| .  . . .|.||||. ||..||.|..|.  .
APEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL

Kinase 94444.m00175.AA TKL-Unique 212-457 36 5.7e-85 288.61 In-house 3-290 (290) Show / Hide
Range on Protein: 212-457
Range on HMM: 3-290/290
Sequence Identity: 36% (105 aa)

QQIGEGASSTVYKGFFKHDKQVAIKKLKY-HKLKGGKLRVFQREVSILASAE-HPCLVHFVGATD----TAP-FCIVTEWINGGSLYALLR---------
  ||||....|||| . . ..||||...   ..   ... | .||...   . || .||..|..     ..| .|||.| ..||||| .|          
NKIGEGGYGQVYKGKW-RGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNN

-TKKPISASKKTSIAFDIARGMNYLHSRH--IIHRDLKSPNVLLDDN-----GRAKICDFGYSRVADDTDVMTKN----------VGTPHWMAPELLDNQ
  ..... ... ..| |||.||.|||..   ||||||||.|.|.| |      ..|||||| |....  . ||.|          .|.. |||||.| . 
NNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMN

-SSYNHMIDVYSYGIVLWEITAQAV------PYRDLDSPQIIAKVVS--SDFRPPIPEGTHPDIVNLIKQCWDRDPNQRPTFSEILNRF
 . |.  .||||.|||||||    .      ||...|. |....| .    .|||||.   ... .||.|||..|| |||.|.||..| 
FCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL

Kinase 94444.m00175.AA Dicty4 208-459 40 3.1e-79 263.93 In-house 1-277 (277) Show / Hide
Range on Protein: 208-459
Range on HMM: 1-277/277
Sequence Identity: 40% (114 aa)

LEEKQQIGEGASSTVYKGFFKHDKQVAIKKLKYHKLK--GGKLRVFQREVSILASAEHPCLVHFVGATDT----AP--FCIVTEWINGGSLYALLRT---
.   | ||.|. ..||||  .  |.||.|||. |. .     |  | .||.|...  || .. | ||  |    .|  .|||||    |.|| ||.    
INIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGAC-TAPRSHPGKMCIVTEYMPKGNLYSLLHDKPS

----KKPISASKKTS---IAFDIARGMNYLHSRH--IIHRDLKSPNVLLDDNGRAKICDFGYSR----VADDTD-VMTKNVGTPHWMAPELLDNQSSYNH
    ..... .  ..   .|||.|||||.||..   |||||||| | | |.| |.|.|||| |.    . | .|  ||  .||| ||||| . .| .|| 
EQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTA-CGTPCWMAPEVMMHQ-PYNE

MIDVYSYGIVLWEITAQAVPYR-DLDSPQIIAKVVSS-DFRPPIPEGTHPDIVNLIKQCWDRDPNQRPTFSEILNR--FKN
  ||||.|||||||     ||    ... ...  | .   |||||  . | .  ||. ||| ||..||.|.||..|     
KADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH

Kinase 94444.m00175.AA LRRK 208-459 28 2.6e-78 266.46 In-house 1-351 (351) Show / Hide
Range on Protein: 208-459
Range on HMM: 1-351/351
Sequence Identity: 28% (101 aa)

LEEKQQIGEGASS-TVYKGFFKH---------------------------DKQVAIKKLKYH----------------------------------KLKG
|.. .|||.|..  .||.. ..                            .. |||||.. .                                  ... 
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCR-

GKLRVFQREVSILASAEHPCLVHFVGATDTAPFCIVTEWINGGSLYALLRTKK---------PISASKKTSIAFDIARGMNYLHSRH--IIHRDLKSPNV
 ..| |..||.|. . .||..|  .| .   |.|.|.| .  |.|| .|. ||          || . |  || .||.||.||||..  ||||||||||.
-AFREFRHEVWIMSHLNHPNIVSLKGFC-IHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNI

LL---D---------DNGRAKICDFGYSR--VADDTDVMTKNVGTPHWMAPELLDNQ--SSYNHMIDVYSYGIVLWEITAQA-VPYRDLDSP------QI
||   .         ..  |||.||| ||   .. . |  . ||.| ||||| . .   ..|.  .|.||.|..|||.      |....|..       .
LLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQ

IAKVVSSDFRPPIPEG-THP-----DIVNLIKQCWDRDPNQRPTFSEILNRFKN
| . ...  ||.||.   .|     .  .||..||. ||..||.||.|. | . 
IEDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ

Kinase 94444.m00175.AA HH498 208-457 34 1.3e-74 235.83 In-house 1-284 (284) Show / Hide
Range on Protein: 208-457
Range on HMM: 1-284/284
Sequence Identity: 34% (97 aa)

LEEKQQIGEGASSTVYKGFFKHDKQVAIKKLKYHK-LKGGK-----LRVFQREVSILASAEHPCLVHFVGAT--DTAPFCIVTEWINGGSLYALL-----
.| . .|| |.   |||| .   | ||.|  .  . .  ..        | |||||.   .||| | ||.|.  |   | |||... .|||. .|     
IEFHEKIGSGSFGKVYKGEWR-NKIVAVKRYRAMAFCCKSDSYQWIVDMFCREVSIMCRLNHPCVVQFVYACCDDPSQFAIVTQYCDNGSLFSILNTIPI

---------RTKK----PISASKKTSIAFDIARGMNYLHS---RHIIHRDLKSPNVLLDDNGRAKICDFGYSRVADDT--DVMTKNVGTPHWMAPELLDN
            |     ..   |  |. |.|.||||||.   . |||||| | |.|.. .|.|.. ||| ||   |   | |||  | . |||||    
GGAGANNNNHNQKNNYRIMDLQSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDGHAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEVFSQ

QSSYNHMIDVYSYGIVLWEITAQAVPYRDLDSPQIIAKVVSSDFRPPIPEG----THPDIVNLIKQCWDRDPNQRPTFSEILNRF
   |   .||.||....||.    ||. ..      |..     |||||          ..||| .||.  |. ||.|..|.   
CQKYSIKVDVFSYAMCIWEMHTREVPFHHYKPAAAAAEMAYHHIRPPIPQTPTAQIPHHWSNLIQMCWHPCPENRPDFDQIVTIL

Kinase 94444.m00175.AA TyrKc 208-457 32 6.7e-73 249.42 SMART 1-280 (280) Show / Hide
Range on Protein: 208-457
Range on HMM: 1-280/280
Sequence Identity: 32% (93 aa)

LEEKQQIGEGASSTVYKGFFKHDKQVAIKKLKYHKLKGGKLRVFQREVSILASA--EHPCLVHFVGATDT--------APFCIVTEWINGGSLYALLRTK
.. ....||||  .||||  |   |||.|.|| ..     .. | || .|. .   .||..| ..|.  .         | .||.|   .|.|   || .
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

KP-ISASKKTSIAFDIARGMNYLHSRHIIHRDLKSPNVLLDDNGRAKICDFGYSRVADDT-------DVMTKNV--GTP-----HWMAPELLDNQSSYNH
.| .. ... |....||.||.||||...|||||   |.|...|...||.||| ||  .|        |. .|    |.       ||||| . | . ...
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFTT

MIDVYSYGIVLWEITAQAVPYRDL-----DSPQIIAKVVSSDFRPPIPEG--------THPDIVNLIKQCWDRDPNQRPTFSEILNRF
  ||.|.|...|||     .          |.| . . | . .|.|.|.          .... ...||||..||..|||||||  .|
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase 94444.m00175.AA Dicty4-Unclassified 208-457 39 2e-72 246.89 In-house 1-263 (263) Show / Hide
Range on Protein: 208-457
Range on HMM: 1-263/263
Sequence Identity: 39% (104 aa)

LEEKQQIGEGASSTVYKGFFKHDKQVAIKKLKYHKLKGG--KLRVFQREVSILASAEHPCLVHFVGATDTAP------FCIVTEWINGGSLYALLR----
.   | ||.|. | |.||  |  | ||.||.   | |     .  | .|| || |  || ||   |.   .|      .|||.| .  | |  .      
IQIDQFIGKGHFSKVHKGNWK-GKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYC-INPRSHKSTMCIVMEFMHKGNLFEVIHSKPS

-TKKPISASK--KTSIAFDIARGMNYLHSRHIIHRDLKSPNVLLDDNGRAKICDFGYSRVADDTDVMTKNVGTPHWMAPELLDNQSSYNHMIDVYSYGIV
  ..||.        .|||||.|| .||.| .||||.|| |.|.| .  .|| ||| ||| | .  ||   ||| | .|| |    |||   |||||...
EQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHE-SYNQKSDVYSYAMM

LWEITAQAVPYRDLDSPQIIAKVVSS-DFRPPIPEGTHPDIVNLIKQCWDRDPNQRPTFSEILNRF
|.|      || .  |.  .|  | .   || ||.   . .  ||| ||  ||| |||. .| .. 
LYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL

Kinase 94444.m00175.AA Pkinase_Tyr 208-457 32 1.9e-71 242.57 Pfam 1-270 (270) Show / Hide
Range on Protein: 208-457
Range on HMM: 1-270/270
Sequence Identity: 32% (90 aa)

LEEKQQIGEGASSTVYKGFFK-----HDKQVAIKKL--KYHKL-KGGKLRVFQREVSILASA-EHPCLVHFVGA-T-DTAP--FCIVTEWINGGSLYALL
..  ...||||  .||||  |     .. .||.|.|  ....     ... | ||..|. .   || .| ..|. | .  |   .||.|   .|.|.  |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQN--CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

RT----KKPISASKKTSIAFDIARGMNYLHSRHIIHRDLKSPNVLLDDNGRAKICDFGYSRVADDTDVM-TKNVGTP---HWMAPELLDNQSSYNHMIDV
|.    |.|.. . . .....||.||.||.|...|||||   |.|...|. .|||||| .|   ..|   .|  |..    ||||| . .   ...  ||
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK-FTTKSDV

YSYGIVLWEITAQA-VP-YRDLDSPQIIAKVVSSDFRPPIPEGTHPDIVNLIKQCWDRDPNQRPTFSEILNRF
.|.|...|||      | | ...  ......  .  | |.||.....| .|.||||. ||..|||||||....
WSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL

Kinase 94444.m00175.AA Pkinase 208-457 27 2e-71 248.43 Pfam 1-293 (293) Show / Hide
Range on Protein: 208-457
Range on HMM: 1-293/293
Sequence Identity: 27% (81 aa)

LEEKQQIGEGASSTVYKGFFKHDKQ-VAIKKLKYHKLKGGKLRVFQR--EVSILASAEHPCLVHFVGAT-DTAPFCIVTEWINGG----SLYALLR--TK
.. ...||.|....|||.  | . . ||.|..|... | .|..   |  |..|...  ||. | . ..  |    ..|.|. .||    .|.....   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KPI--SASKKTSIAFDIARGMNYLHSRHIIHRDLKSPNVLLDDNGRA----KICDFGYSRV--ADDTDVMTKNVGTPHWMAPELLDNQSSYNHMIDVYSY
...  |     ...  |.||..|.||. |||||||. |.|.|.||      |||||| ...        ||  .|||..||||..  .. | . .|..|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GIVLWEITAQAVPYRDL------DSPQIIAKVVSSDFRPPIPEGTH-------------------PDIVNLIKQCWDRDPNQRPTFSEILNR--F
|..|.|      |...       |  |.|... . ... ..|.                      ..   .|| |...||..|||. .||.   |
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 94444.m00175.AA S_TKc 208-462 28 5.8e-71 242.97 SMART 1-231 (231) Show / Hide
Range on Protein: 208-462
Range on HMM: 1-231/231
Sequence Identity: 28% (76 aa)

LEEKQQIGEGASSTVYKGFFKH-DKQVAIKKLKYHKLKGGKLRVFQREVSILASAEHPCLVHFVGATDTAPFCIVTEWING--GSLYALLRTKKP-----
 |  ..||.|| ..|||.  |. ...||||..|         . ..||..|| .  || .|.. .. ..  ...|.| ..|  |.|. ... ...     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-ISASKKTSIAFDIARGMNYLHSRHIIHRDLKSPNVLLDDNGRAKICDFGYSRVADDTDVMTKNVGTPHWMAPELLDNQSSYNH-MIDVYSYGIVLWEIT
 ..     ...  |.....|.||..|||||||  |.|||.  . |||||| .|.       |  .|||..||||.|    .|..  .|..| |..|.|  
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEML

AQAVPYRDLDSPQIIAKVVSSDFRPPIPEGTHPDIVNLIKQCWDRDPNQRPTFSEILN----RFKNGFM
.   |..    .| . |..             |.  ..|..|...||..|||  |.|.      .  ..
CGYPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 94444.m00175.AA TK 208-457 17 4.9e-69 230.33 In-house 1-486 (486) Show / Hide
Range on Protein: 208-457
Range on HMM: 1-486/486
Sequence Identity: 17% (83 aa)

LEEKQQIGEGASS---TVYKGFFKHDK--------------------------QVAIKKLK-YHKLKGGKLRV--------------FQREVSILAS--A
..  ...|||.     .||||  . ..                          .||.| ||  .       .               . .| ... .   
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

EHPCLVHFVG-ATDT------------APFCIVTEWINGGS----LYALLRTKKP---------------------------------------------
.|| .|...|  |.              |..||.|. ..|.    |   ||...|                                             
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------ISASKKTSIAFDIARGMNYLHSR------HIIHRDLKSPNVLLDDNGR-----------AKICDFGYSR
                               ..   .  ....||.|| ||||.      ...||||   |.|...|..           .||.||| ||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----VADDTD-----VMTKNVGTPH-------------------------WMAPELLDNQS--------SYNHMIDVYSYGIVLWEITAQA-VPYRDLD
      | | .     . ... ||.                          ||||| |. .          . .  ||.|.|...|||   . .||    
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

SP---------QIIAKVVSSD--------------FRPPIPEGTHP-------------DIVNL-IKQCWDRDPNQRPTFSEILNRF
|          | . . . .               .|.| |.. ..             ... . ..|||..||..|||||......
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase 94444.m00175.AA Dicty5 211-461 39 7.8e-69 235.0 In-house 4-260 (260) Show / Hide
Range on Protein: 211-461
Range on HMM: 4-260/260
Sequence Identity: 39% (102 aa)

KQQIGEGASSTVYKGFFKHDKQVAIKKLKYHKLKGGKLRVFQREVSILASAE--HPCLVHFVGA--TDTAPFCIVTEWINGGSLYALLRTK-K----PIS
 . |  ||| .||.| .|  . |||| .      .  .  |.||| |.   .  || .. . ||   ..    .||| .  |||  .|. . |    ||.
HDWIASGASGRVYNGIYK-GMDVAIKVYSQENCMCFDWNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQPIA

ASKKTSIAFDIARGMNYLHSRHIIHRDLKSPNVLLDDNGRAKICDFGYSRVADDTDVMTKNVGTPHWMAPELLDNQSSYNHMIDVYSYGIVLWEITAQAV
   . ..| |||..| .|||  |||||||| |.|.  |  .|| ||| ||  |    || .|||. |||.||   |  |    ||||.||||||. ..  
YFQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFNGQ-PYHQKCDVYSFGIVLWEMFTRKE

PYRDLDSPQIIAKVVSSDFRPPIPEGTHPDIVNLIKQCWDRDPNQRPTFSEILNRFKNGF
|| .. .   |.  | .  || ||      | |||| ||   | .||.| ||.  |.   
PYDNINNWN-IPVMVMKGERPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII

Kinase 94444.m00175.AA DRK 232-459 36 6.4e-62 208.49 In-house 24-258 (258) Show / Hide
Range on Protein: 232-459
Range on HMM: 24-258/258
Sequence Identity: 36% (87 aa)

QVAIKKLKYHKLK-GGKLRVFQREVSILASAEHPCLVHFVGA-TDTAPFCIVTEWINGGSLYALLRTKK-PISASKKTSIAFDIARGMNYLHSRH--IIH
|||.|.|. |       |  |.||. ..    ||  . | |. .     ||..| .  ||||  |   .  .. .   ...||.|.||.|||..   |||
QVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLMKQMMFDCAKGMIYLHCCNPIIIH

RDLKSPNVLLDDNGRAKICDFGYSR----VADDTDVMTKNVGTPHWMAPELLDNQSSYNHMIDVYSYGIVLWEITAQAVPYRDLDSPQIIAKVVSSDFRP
||||| | | |.. . |. ||| |     . . .  ||  .||| | ||| | ||  |    ||||..|||||.     ||      |..  |     ||
RDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTM-CGTPCWTAPEVLRNQ-RYTEKADVYSFAIVLWECVTRQDPYFGMPTFQVVFSVGRHGMRP

PIPEGTHPDIVNLIKQCWDRDPNQRPTFSEILNRFKN
|.|.   |  . |.. ||. || .||.. |.| |   
PMPQWCPPKYIQLMNDCWNEDPQHRPSMQECLERLEA