Gene 93242.m00198 (T.vaginalis)

93242.m00198

Species: T.vaginalis
Alias: TvagK0234, 93242.m00198
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
93242.m00198.AA Protein None 212 None Fasta, JSON
93242.m00198.kin_dom Protein Kinase Domain None 151 None Fasta, JSON

Protein domain

Protein domains of 93242.m00198.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 93242.m00198.AA CAMK 3-153 21 2.9e-44 140.06 In-house 183-425 (425) Show / Hide 
Range on Protein: 3-153
Range on HMM: 183-425/425
Sequence Identity: 21% (52 aa)

KYIQGIVLSVKACHDRNIAHCDIKPSNFMLDQY-----------------GRVKVGNFGLATLLLV------------------------DDENKKIKGT
.|.. |.  |. ||..||.|.|.|| | .||.                  . .|.  ||.|. .                          ..  |   ||
RYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGT

RYFMA-PEVITQ-------------KEYDLMKADIWAIGVTLYYLTTLTYPFYAT-------------DQDSLFSLIIKGNYRID--RVPDSM-------
 ..|| |||. .             |.|.  |.|.|..|| || . . ..|||.              ..  ||  |.||.|. .   ....        
PEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEW

---------------LRQVILKCLETNPNDRPTVDQLIEMPYF
                .. | |.|...|..|.|..|  . | .
WDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Pkinase 93242.m00198.AA Pkinase 3-153 26 4.8e-41 146.2 Pfam 112-293 (293) Show / Hide 
Range on Protein: 3-153
Range on HMM: 112-293/293
Sequence Identity: 26% (48 aa)

KYIQGIVLSVKACHDRNIAHCDIKPSNFMLDQYGRV----KVGNFGLATL--LLVDDENKKIKGTRYFMAPEVITQKEYDLMKADIWAIGVTLYYLTTLT
.|.  |.  .. ||...| |.|.||.|...|. | .    |.. |||| .  .  .  .. . ||...||||||   .|.  |.|.|..|..||.. .  
FYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGR

YPFYAT------DQDSLFSLIIKGNYRIDRVPD---------------------SMLRQVILKCLETNPNDRPTVDQLIEMPYF
 ||.        ||. .. .| .. .. |.  .                     . ....| .||. .|..||| .|. . |.|
PPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 93242.m00198.AA CAMKL 3-153 31 4e-37 115.93 In-house 131-297 (297) Show / Hide 
Range on Protein: 3-153
Range on HMM: 131-297/297
Sequence Identity: 31% (53 aa)

KYIQGIVLSVKACHDRNIAHCDIKPSNFMLDQYG--RVKVGNFGLATLLL-V----DDENKKIKGTRYFMAPEVITQ--KEYDLMKADIWAIGVTLYYLT
.| . ||  |. ||...|.| |||| | .||. |   .|.  ||....   .    ..  |   |.  .||||..    |.||  |.|||..||.|| . 
RYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMV

TLTYPFYAT--------DQDSLFSLIIKGNYRIDRV--PDSMLRQVILKCLETNPNDRPTVDQLIEMPYF
. ..|| .         ..  |.  |..| |...    ..  .|. | | |..||..|||..|. . | .
CGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 93242.m00198.AA Ciliate-E2-Unclassified 3-153 24 7e-35 118.44 In-house 147-352 (352) Show / Hide 
Range on Protein: 3-153
Range on HMM: 147-352/352
Sequence Identity: 24% (50 aa)

KYIQGIVLSVKACHDRN-IAHCDIKPSNFMLDQYG---RVKVGNFGLATLLLVD----------------DENKKIKGTRYFM----APEVITQKEYDLM
.|.  |..  . .|  | | | ||||.| ..|. |   ..|.  ||..  .  .                .. . . || ..|    ||||. ...|| .
FYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHS

---KADIWAIGVTLYYLTTLTYPFYATDQDS----------------LFSLIIKGNY------------RIDRVPDSMLRQVILKCLETNPNDRPTVDQL
   |.|||. || ||.. . .||||......                |.. |...|.            ...     .... . |.|. ||| |.| .|.
KAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQI

IEMPYF
.. |.|
LNHPWF
Kinase 93242.m00198.AA Ciliate-E2 4-153 23 7.1e-34 113.65 In-house 165-365 (365) Show / Hide 
Range on Protein: 4-153
Range on HMM: 165-365/365
Sequence Identity: 23% (50 aa)

YIQGIVLSVKACHDRN-IAHCDIKPSNFMLDQYGRVKVGNFGLATLLLVDDENKK--------------------------------IKGTRYFMAPEVI
||  |.| .. .| .| | | ||||.| ..     .|.  |||.. .  | .|.                                 | || ..||||..
YIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEIL

TQKEYDL--------MKADIWAIGVTLYYLTTLTYPFYATDQDSLFSLIIKGNYRID-----------------RVPDSML-RQVILK----CLETNPND
  |.||          |.|||..||.||.. .  .||        .  |........                     |    . | |    .|. .|. 
NGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEK

RPT-VDQLIEMPYF
|.|  .|... |.|
RITGWEQILNHPWF
Kinase 93242.m00198.AA MARK 8-153 33 9e-34 107.89 In-house 113-262 (262) Show / Hide 
Range on Protein: 8-153
Range on HMM: 113-262/262
Sequence Identity: 33% (51 aa)

IVLSVKACHDRNIAHCDIKPSNFMLDQYG--RVKVGNFGLATLLLVDDENKKIKGTRYFMAPEVITQKEYDLMKADIWAIGVTLYYLTTLTYPFYATD--
||  |. ||..||.|.|||| | ..|. |   .|   ||...    .   .   ||  .||||.. .|.||  |.|||. || ||.... ..|| ...  
IVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQD

QDSLFSLIIKGNYR-IDRVPDSMLRQVILKCLETNPNDRPTVDQLIEMPYF
.  |.  | .|.|.  ..|... .|. | . | .||..|||.... . | .
YKELYKKILRGKYDIPCHVSKE-CRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 93242.m00198.AA NEK 8-153 33 1.6e-33 115.6 In-house 123-286 (286) Show / Hide 
Range on Protein: 8-153
Range on HMM: 123-286/286
Sequence Identity: 33% (56 aa)

IVLSVKACHDR-----NIAHCDIKPSNFMLDQYGR----VKVGNFGLATLLLVDDENKK--IKGTRYFMAPEVITQKEYDLMKADIWAIGVTLYYLTTL-
..| .| .|||     .| | ||||.| .|.  ..    ||.| ||.. .|  . .  .    || |.|.|||. .| |.  |.|||..|. || . || 
MCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNKPYN-NKSDIWSLGCVLYEMCTLK

-TYPFYAT--DQDSLFSLIIKGNYRIDRVPDS-----MLRQVILKCLETNPNDRPTVDQLIEMPYF
   ||.|.  .. ||.  |.||    ...|.       |...| ..|  .| .||...|..|||. 
PKHPFEAWDMNMPSLYMKIMKG-PQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase 93242.m00198.AA CAMKK 3-153 22 1.9e-32 99.95 In-house 180-396 (396) Show / Hide 
Range on Protein: 3-153
Range on HMM: 180-396/396
Sequence Identity: 22% (49 aa)

KYIQGIVLSVKACH-DRN-------------------IAHCDIKPSNFMLDQYG---RVKVGNFGLATLLLVDDEN-KK-----------IKGTRYFMAP
|| ..... .. .| ...                   | | ||||.|  .|. |   .||.  || .. .  .|.. .            . || .||||
KYFRDCIKGLEYLHNYQKACSYIIIYINEFIIDHFQDIIHRDIKPQNILIDEEGCGEHVKIADFGVSHIFEGQDQTLSNCESCFQRELNKTAGTPAFMAP

EVITQ-KE--------------YDLMKADIWAIGVTLYYLTTLTYPFYATDQDSLFS---LIIKGN--YRI------------DRVPDSMLRQVILKCLE
|...  ..              |.  .||||| |||||...... ||....   |.     |.. .  ...            . ... .|  .|...||
ELCSKENQKENYNGYKYRFRFIYCGKAADIWALGVTLYCFVFGKCPFWHNNLMQLHHNYMKIKNDPIKFPENKEMLNNVSIYCPEISE-DLKDLIKRMLE

TNPNDRPTVDQLIEMPYF
 || .| |..|... | .
KNPTKRITIPQIKVHPWV
Kinase 93242.m00198.AA CAMKK-Unclassified 3-153 22 4.7e-32 101.5 In-house 182-392 (392) Show / Hide 
Range on Protein: 3-153
Range on HMM: 182-392/392
Sequence Identity: 22% (48 aa)

KYIQGIVLSVKACHDRN---------------------IAHCDIKPSNFMLDQYGR-----VKVGNFGLATLLLVDDEN--KKIKGTRYFMAPEVITQK-
|| ... . .. .|..|                     | | |||| |  .|. ..     .|.  ||.....  ....  |   || .|||||... . 
KYFRQCCKGLQYMHNFNQACSYIIIYINEFDKIDHFQDIIHRDIKPQNILIDHEDNDKGEHFKIADFGISVIMEHEQQKKLKNNAGTYCFMAPEFWSKEN

---EYDL-----------------------MKADIWAIGVTLYYLTTLTYPFYATDQDSLFS-LIIKGN--YRI---DRVPDSMLRQVILKCLETNPNDR
    |.                         |||||. |||.|...... ||....   ||  .|....   ..   .  ..  .   | |... || .|
FKYDYNDYSFLPGTFNPLRKTYRIERICFYKKADIWSLGVTFYCMVYHSLPFWHKNLQELFHQMICQKEINFPPQYHPHCSH-EFKDLIQKMCDKNPKKR

PTVDQLIEMPYF
 |.||... |.|
ITIDQMLVHPWF
Kinase 93242.m00198.AA ULK 16-153 21 2.5e-31 108.43 In-house 143-324 (324) Show / Hide 
Range on Protein: 16-153
Range on HMM: 143-324/324
Sequence Identity: 21% (40 aa)

HDRNIAHCDIKPSNFMLDQY------------GRVKVGNFGLATLLLVDDENKKIK----------GTRYFMAPEVIT----QKEYDLMKADIWAIGVTL
|..|| |.||||.| ..               |..|.. ||.|  .  ..... .           || ..|||...     ||.|.  |.||| .|. .
HKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIF

YYLTTLTYPFYATDQDSLF----SL----------IIKGNYRIDRVP-----DSMLRQVILKCLETNPNDRPTVDQLIEMPYF
|.. .  |||..    ...    .|          | . . ... .|      . ... | ..|. ...|| . ......| |
YEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 93242.m00198.AA ULK 16-153 23 3.1e-31 106.32 In-house 147-329 (329) Show / Hide 
Range on Protein: 16-153
Range on HMM: 147-329/329
Sequence Identity: 23% (43 aa)

HDRNIAHCDIKPSNFMLDQY------------GRVKVGNFGLATLLLVD----DENKKIK------GTRYFMAPEVIT----QKEYDLMKADIWAIGVTL
|..|| |.||||.| ...              |..|.. ||.|  .  |    . ..  .      || ..|||...     ||.|.  |.||| .|. .
HKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIF

YYLTTLTYPFYATDQDSLFSLIIKGNYRI--------------------DRVPDSMLRQVILKCLETNPNDRPTVDQLIEMPYF
|.. .  .||||    ... .||. ....                    | .  . ... | ..|. ...|| . ..|...| |
YEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
S_TKc 93242.m00198.AA S_TKc 2-153 18 2.5e-13 18.46 SMART 1-231 (231) Show / Hide 
Range on Protein: 2-153
Range on HMM: 1-231/231
Sequence Identity: 18% (47 aa)

FK-----------------------------------------------------------------YIQG-----------------------------
..                                                                 |. |                             
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPEHARFYM

--IVLSVKACHDRNIAHCDIKPSNFMLDQYGRVKVGNFGLATLLLVDDENKKIKGTRYFMAPEVITQKEYDLMKADIWAIGVTLYYLTTLTYPFYATDQD
  |.. .. ||...| |.|.||.| .||.  ..|.. ||||..|      . . ||...|||||.    |.  |.|.|..|..|| . .   ||.  ...
YQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQ

SLFSLIIKGNYRIDRVPDSMLRQVILKCLETNPNDRPTVDQLIE-------MPYF
 .| .|           .. ... | |||. .|..|||. .. .       .|.|
MMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
TyrKc 93242.m00198.AA TyrKc 2-151 12 1.7e-05 -133.82 SMART 1-280 (280) Show / Hide 
Range on Protein: 2-151
Range on HMM: 1-280/280
Sequence Identity: 12% (36 aa)

FKYIQ-----------------------------------------------------GIVLSV--------------------------KACH------
 . ..                                                     |....                           ....      
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMK

-----------------DRNIAHCDIKPSNFMLDQYGRVKVGNFGLATLLLVD------DENKKIK---GTR-----YFMAPEVITQKEYDLMKADIWAI
                 ..|. | |.   | ...  ..||.. |||.  .  |      .. .. |   |..       ||||.|  ...   | |.|. 
DLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT-KSDVWSF

GVTLYYLTTLTYPFYA------TDQDSLFSLIIKG--NYRIDR--------VPDSMLRQVILKCLETNPNDRPTVDQLIEMP
||... . |.  . |        . . .. .. .|    . .          || | . ....| . .|.||||  ...|  
GVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF