Gene 86800.m00108 (T.vaginalis)

86800.m00108

Species: T.vaginalis
Alias: 86800.m00108, TvagK0789
External Links:
Annotation:

Classification

Group: PKL
Family: PIK
Subfamily: FRAP

Sequence

Name Sequence Type Origin Length Description Download
86800.m00108.AA Protein None 2192 None Fasta, JSON
86800.m00108.kin_dom Protein Kinase Domain None 255 None Fasta, JSON

Protein domain

Protein domains of 86800.m00108.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 86800.m00108.AA FRAP 1994-2145 31 4.2e-22 78.06 In-house 93-251 (251) Show / Hide 
Range on Protein: 1994-2145
Range on HMM: 93-251/251
Sequence Identity: 31% (50 aa)

NDYDDLSAEDKMKAYKQSLSSTRGDDLEAVIVRGSVSYQGWMERRSMYIGSLSVKAVTGYIFGVGDRKLTNIMMELNTSKVYNTKYYPCF-------VKK
|||| |   .|   ..  .  | |.||  ..   | .   |.|||  |  || .  . ||| | ||| . |||..  | |.    .  ||          
NDYDHLPLMNKVEIFRYIMNNTKGEDLKKLLWLKSPNSEIWFERRTNYTRSLATMSMAGYILGLGDRHPSNIMLQRYTGKIVHIDFGDCFEVAMRREKFP

QIVPFRLTRIMANALDVAGVNGVLEREMNDAMDIVRESKDFIVCTLEPSIRDEKLNWTS
  .||||||.. ||....|..|         |...|| |. ..  ||  . |  ..|  
EKIPFRLTRMLVNAMEACGIEGNYRNTCELVMKVIREHKESVMAVLEAFVYDPLFYWRL
Kinase 86800.m00108.AA PIKK 1994-2135 29 7.5e-19 65.52 In-house 142-290 (290) Show / Hide 
Range on Protein: 1994-2135
Range on HMM: 142-290/290
Sequence Identity: 29% (44 aa)

NDYDDLSAEDKMKAYKQSLSSTRGDDLEAVIVRGSVSYQGWMERRSMYIGSLSVKAVTGYIFGVGDRKLTNIMMELNTSKVYNTKYYPCFV-KKQ-----
..|.... ..| ..    .. | .|..    .| . . . | |||..|. |. |  . ||| | ||| . |||    | ..    .  ||  ..|     
MMYQHWPLHEKVEVFREQMQNTPPDMFKKWFWRKFPDPEIWWERRENYTRSYAVMCMVGYILGLGDRHPENIMIDMQTGEIVHIDFGCCFESAMQRLPVP

-IVPFRLTRIMANALDVAGVNGVLEREMNDAMDIVRESKDFIVCTLEPS
 .||||||| | ||. . ||.||. | . ..| . |.... .  ..|  
EKVPFRLTRNMVNAMGPMGVEGVFRRCCEHVMMCMRQHRETLMTVCEVF
Kinase 86800.m00108.AA ATR 2032-2135 28 1.1e-14 46.0 In-house 158-267 (267) Show / Hide 
Range on Protein: 2032-2135
Range on HMM: 158-267/267
Sequence Identity: 28% (31 aa)

QGWMERRSMYIGSLSVKAVTGYIFGVGDRKLTNIMMELNTSKVYNTKYYPCFVK------KQIVPFRLTRIMANALDVAGVNGVLEREMNDAMDIVRESK
| |   |. |. |  | .. ||| | |||   ||...  .  .    |   | .        |||||||. | ...   . .|.  | . . | ..|. .
QQWYSSRENYCRSYAVWCMVGYIIGLGDRHTDNILIDKINGECVHVDYNCIFNSGEQFEVPEIVPFRLTHNMVFGMGPMKTYGLFRRACEVIMMCMRDHR

DFIVCTLEPS
| |.  ..  
DDIMSVWDCF
Kinase 86800.m00108.AA ATM 2034-2161 31 3.1e-14 41.5 In-house 133-265 (304) Show / Hide 
Range on Protein: 2034-2161
Range on HMM: 133-265/304
Sequence Identity: 31% (42 aa)

WMERRSMYIGSLSVKAVTGYIFGVGDRKLTNIMMELNTSKVYNTKYYPCFVKKQI------VPFRLTRIMANALDVAGVNGVLEREMNDAMDIVRESKDF
| |.|  |  |    .. ||| |.|||   ||..      .        | . .|      ||||||| .   . . || ||  |     |...| |.. 
WFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFEQGKILPTPETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVMRNSQET

IVCTLEPSIRDEKLNWTSNPENALDFVAKRLSDE
..   |  . |    || ||  || .. .|  ||
LLTIVEVLLYDPLFDWTMNPLKAL-YLQQRPEDE
Kinase 86800.m00108.AA PI3_PI4_kinase 2034-2145 24 2.1e-10 40.2 Pfam 160-300 (300) Show / Hide 
Range on Protein: 2034-2145
Range on HMM: 160-300/300
Sequence Identity: 24% (35 aa)

WMERRSMYIGSLSVKAVTGYIFGVGDRKLTNIMM--ELNTSKVYNTKYYPCFV--------KKQIVPFRLTR------IMANAL------DVAGVNGVLE
| |.|. .. |. . .| .||.|.||| . |||.  .  | ...   .  ||         |   ||||.|.       | .|.      |. |  | ..
WWEARDNFVRSCAGMCVVDYILGNGDRHNDNIMVKDDKTTGHLFHIDFGHCFPHWKMKHFHKPERVPFRWTHWPQAKKPMVHAMGGYISLDPSGDYGWFR

REMNDAMDIVRESKDFIVCTL-------EPSIRDEKLNWTS
... .|. ..|. .......|       |  ..|. ..|.|
DYCWHAYRALRRHMNLCMNLLKKAVMRGECMVHDGLPMWRS
PI3Kc 86800.m00108.AA PI3Kc 1921-2189 16 8.4e-08 -40.76 SMART 1-336 (336) Show / Hide 
Range on Protein: 1921-2189
Range on HMM: 1-336/336
Sequence Identity: 16% (55 aa)

AFI---------DERSFILMRMISKIIKSY-----QKPNLVPPLVQTIPLTENISL-EKSSPCFSLEEAIKQRRRRQSVCVDERTWI-------------
|.|         |.| . . |.. || ..      ..  . |. .  ||. ... . |  . | .| .  | ..  ...  | . |.             
AVIFKCGDDLRQDMRMMQMFRLMNKIWQKDKECRRRDLHMRPYKC--IPTGPKCGMIEWVPNCETLHQIQKKYHKWKKMPMDYHQWFMFDMLVPEIQKNM

------------LNDYDDLSAEDKMKAYKQSLSSTRGDDLEAVIVRGSVSYQ-GWMERRSMYIGSLSVKAVTGYIFGVGDRKLTNIMMELNTSKVYN---
              .|.... . . | .   .... ...|    .. . ..   | |.|. .. |. .  . .||.|.||| . |||.  .| ..     
YMMIWHQQACHWMMMYQHMTHMEWLKYFEGATCPFKPPVLYDWFWEHFPDPNEDWWEARDNFTRSCAGYCMVTYILGIGDRHNDNIMLDMKTGHCFHIDF

----TKYYPCFVKKQ-----IVPFRLTRIMANALD----VAGVNGVLEREMNDAMDIVRESKDFIVCTLEPSIRDEK-LNWTSNPENALDFVAKRLSDEN
    ... | ... .      ||||||. | ..      ..|. |   . .  |. ..|.... |....|  ..|.   .|... |...... .|.  ..
GHIFGHG-PKKPGFKHHHRERVPFRLTHDMVYVMGGGGKPSGYFGYFRTCCCRAYRAMRKHSNLIMNLFEMMVYDPIMPCWRMM-EKDIKYLRQRFRLDH

DSQELVLKLI-------------DSATSDTNISRMPADWN
 | |.... .             .| |. .. . .    .
LSDEEAAQYFMQTMCTKLIEHSNESWTTRMYWMFHNWAQY
Kinase 86800.m00108.AA FATC 2168-2192 40 1.4e-05 20.92 Pfam 9-33 (33) Show / Hide 
Range on Protein: 2168-2192
Range on HMM: 9-33/33
Sequence Identity: 40% (10 aa)

VLKLIDSATSDTNISRMPADWNSWW
| .||..||.  |...|   | .||
VDRLIQEATDPENLCQMYIGWCPWW
Kinase 86800.m00108.AA SMG1 2041-2085 40 3.3e-05 13.05 In-house 190-234 (242) Show / Hide 
Range on Protein: 2041-2085
Range on HMM: 190-234/242
Sequence Identity: 40% (18 aa)

YIGSLSVKAVTGYIFGVGDRKLTNIMMELNTSKVYNTKYYPCFVK
|  |  | .. ||| |.||| | |..... |  |    |  || |
YARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYPICFEK
Kinase 86800.m00108.AA DNAPK 2090-2145 26 0.00334 7.29 In-house 246-301 (301) Show / Hide 
Range on Protein: 2090-2145
Range on HMM: 246-301/301
Sequence Identity: 26% (15 aa)

PFRLTRIMANALDVAGVNGVLEREMNDAMDIVRESKDFIVCTLEPSIRDEKLNWTS
||||||   | .   ..||..   |  .|   |  .   . . .  |.|  . |  
PFRLTRCFINLMSPMKINGIMYQIMIHSMMAFRKDRNILTNFCDVFINDPSFDWKN
Kinase 86800.m00108.AA DNAPK 2050-2071 36 0.024554 4.09 In-house 199-220 (301) Show / Hide 
Range on Protein: 2050-2071
Range on HMM: 199-220/301
Sequence Identity: 36% (8 aa)

VTGYIFGVGDRKLTNIMMELNT
. ..| |.||| | | |    .
ISHWILGIGDRHLNNFMVNMEN