Gene 97483.m00096 (T.vaginalis)
97483.m00096
Species: T.vaginalis
Alias: 97483.m00096, TvagK0983
External Links:
Annotation:
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
---|---|---|---|---|---|
97483.m00096.AA | Protein | None | 398 | None | Fasta, JSON |
97483.m00096.kin_dom | Protein Kinase Domain | None | 231 | None | Fasta, JSON |
Protein domains of 97483.m00096.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 97483.m00096.AA | AGC | 182-264 | 24 | 4.7e-22 | 52.41 | In-house | 275-395 (395) | Show / Hide |
Range on Protein: 182-264 Range on HMM: 275-395/395 Sequence Identity: 24% (31 aa) PPEYLVANSYSAAADFWD--LGIFLYYCVVGGSPFPMDN----------KETITGMIV----------AYP----------NFLSQSIIDLFKKLITASP .|| | |. |.| | ||...| ..| .|| || .. . | .| ..|. || |||.. | APEIL----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDP AHRYN----------TRDIKEHPWF ..| . .||.|||| EKRLGCGGNDFGDKGAEEIKNHPWF |
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Kinase | 97483.m00096.AA | Ciliate-E2-Unclassified | 41-264 | 19 | 7.7e-21 | 69.04 | In-house | 34-352 (352) | Show / Hide |
Range on Protein: 41-264 Range on HMM: 34-352/352 Sequence Identity: 19% (64 aa) VSIKVYSKKFLAIDNNKEYFENDLYCLK----------------TFFHPFIAKYITKLEDSKFVYIVLEPMRGGTFKELLEAKTR--------------- ..... .|. . | .. .. . ..| . |||| |.. .| . .|||.| ..||. .. .. . KIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQR --WNEAQAR-----PYFAQLYFIIEYMQTQMNMIHGNLCLDILMVDENN---VIRCVDFWGTQ--------------------PNSGSAACGTQLFAPLP | ||. ||||. .||. . | || .. .. ...|.|. |. || .. . ||| . | KIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMP-Q FQPPEYLVANSYS----AAADFWDLGIFLYYCVVGGSPFPMDNKET----------------ITGMIVA-------YPN-----FLSQSII----DLFKK ..||.| . |. ..|.| ||. ||... | ||. |.| . | . .|. .|.. . ||..| YTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQK LITASPAHRYNTRDIKEHPWF .. | |.. .|..|||| MLKKNPNKRITFEQILNHPWF |
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Kinase | 97483.m00096.AA | MELK | 32-264 | 25 | 5.1e-20 | 64.81 | In-house | 18-254 (254) | Show / Hide |
Range on Protein: 32-264 Range on HMM: 18-254/254 Sequence Identity: 25% (60 aa) AHHSVTSQEVSIKVYSKKFLAIDNNKEYFENDLYCLKTFFHPFIAKYITKLEDSKFVYIVLEPMRGGTFKELLEAKTRWNEAQARPYFAQLYFIIEYMQT | | .| | |.||. |. | | . . .. || . | | . .| . ...|.| || . . . . | .| ..| .| |. | |. ACHILTNQMVAIKIMDKNQLGHDLPR--VKTEMDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEEETRHFFRQIVSAIAYVHS QMNMIHGNLCLDILMVDENNVIRCVDFWGTQPNSGSAACG--TQLFAPLPFQPPEYLVANSYSAA-ADFWDLGIFLYYCVVGGSPFPMDNKETITGMIVA | | .| . |..||. .. .|| | . . || . .| . || | .|| || ..| || || . . |. QG-YAHRDLKPENLLFDEDHHLKLIDFGLCAKTKGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGFLPFDDDNMMIMYKKIMS ----YPNFLSQSIIDLFKKLITASPAHRYNTRDIKEHPWF |..|| . ..| .... | .| ... .||| GCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV |
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Kinase | 97483.m00096.AA | PKN | 72-264 | 29 | 5.2e-18 | 58.14 | In-house | 61-260 (260) | Show / Hide |
Range on Protein: 72-264 Range on HMM: 61-260/260 Sequence Identity: 29% (60 aa) HPFIAKYITKLEDSKFVYIVLEPMRGGTFKELLEAKTRWNEAQARPYFAQLYFIIEYMQTQMNMIHGNLCLDILMVDENNVIRCVDFWGTQPNSGSAACG |||. .. . .. |. |.| . || . ..|..|. | | ..|. . ..| | || |..|.. .. || . . | HPFLVNLFACFQTEEHVCFVMEYAMGGDLMMHIHEDV-FSEPRACFYAACVVLGLQYLH-EHKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDR- TQLFAPLP-FQPPEYLVANSYSAAADFWDLGIFLYYCVVGGSPFPMDNKETITGMIVA----YPNFLSQSIIDLFKKLITASPAHRY-----NTRDIKEH | | | | || | .|| | |.| ||. .| .|| .||| |. | . || || ||| |.. ..|. .| .| ||| . TSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLIYEMLVGECPFPGDDEEEVFDCIVNDDVRYPRFLSVEAIAIMRRLLRKNPERRLGAGERDAEDIKMQ PWF |.| PFF |
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Kinase | 97483.m00096.AA | Ciliate-E2 | 178-264 | 23 | 8e-16 | 50.79 | In-house | 251-365 (365) | Show / Hide |
Range on Protein: 178-264 Range on HMM: 251-365/365 Sequence Identity: 23% (28 aa) LPFQPPEYLVANS---------YSAAADFWDLGIFLYYCVVGGSPFPMDNKETITGMIVAYPNF------------------LSQSIIDLFKK----LIT .....|| | . |. ..|.| ||. ||... | || . | . .|.. .||. .||.|| .. PGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQ ASPAHRYN-TRDIKEHPWF | |.. .|..|||| KDPEKRITGWEQILNHPWF |
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Kinase | 97483.m00096.AA | CAMKL | 178-264 | 24 | 1.6e-15 | 45.88 | In-house | 197-297 (297) | Show / Hide |
Range on Protein: 178-264 Range on HMM: 197-297/297 Sequence Identity: 24% (25 aa) LPFQPPEYLVA--NSYS-AAADFWDLGIFLYYCVVGGSPFPMDN-------------KETITGMIVAYPNFLSQSIIDLFKKLITASPAHRYNTRDIKEH .|...|| . .| ..| | .|. || |.| || |. |. .. ....| . .|| .|. . | .|.. .|..| PPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNH PWF ||. PWM |
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Kinase | 97483.m00096.AA | Delta | 72-264 | 23 | 1.1e-14 | 49.56 | In-house | 59-259 (259) | Show / Hide |
Range on Protein: 72-264 Range on HMM: 59-259/259 Sequence Identity: 23% (47 aa) HPFIAKYITKLEDSKFVYIVLEPMRGGTFKELLEAKTRWNEAQARPYFAQLYFIIEYMQTQMNMIHGNLCLDILMVDENNVIRCVDFWGTQPNSGSAACG |||... . .... |.| . || . . |..|. || | . . .... .. ..| | || ...| . |. || . | HPFLCHLFCTFQTKEHLFFVMEYLNGGDLMYHIQQCHRFDEKRARFYACEIICGLQFLHKK-GIIYRDLKLDNVLLDCDGHIKIADFGMCKENMYGE-KK TQLFAPLP-FQPPEYLVANSYSAAADFWDLGIFLYYCVVGGSPFPMDNKETITGMIVA----YPNFLSQSIIDLFKKLITASPAHRYNT-----RDIKEH .. | | . || . . |... |.| |. .| ..| ||| .. . . |. || .... |..|||. | .| ||..| ASTFCGTPDYIAPEIIKGQKYNHSVDWWSFGVLMYEMLIGQSPFHGEDEDELFWSICNDRPWYPRWITKEAKDCLKKLFERDPEKRLGVQYCPKGDIRQH PWF ..| CFF |
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S_TKc | 97483.m00096.AA | S_TKc | 22-264 | 22 | 1.4e-14 | 36.93 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 22-264 Range on HMM: 1-231/231 Sequence Identity: 22% (60 aa) MKNERF-------VLWGAHHSVTSQEVSIKVYSKKFLAIDNNKEYFENDLYCLKTFFHPFIAKYITKLEDSKFVYIVLEPMRG--GTFKELLEAKTR--- . | . . ..| | ..| ||. . | ... . .|| ||.| |.. .| ...|.|.| . | |. ..... . | YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ---WNEAQARPYFAQLYFIIEYMQTQMNMIHGNLCLDILMVDENNVIRCVDF-WGTQPNSGSAACGTQLFAPLPFQPPEYLVANSYSA-AADFWDLGIFL .| .|| |..|. .||. . . || | . ...|| .| || .| | . . . .|| | .|. ..| | .|. | RFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL YYCVVGGSPFPMDNKETITGMIVAYPNFLSQSIIDLFKKLITASPAHRYNTRDIKE-------HPWF | ...| ||| . ... .|. |.. .|. .|. . |..|. .. . |||| YEMLCGYPPFP--QMQMMFKKIG------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | 97483.m00096.AA | RSK | 182-264 | 28 | 8.4e-12 | 39.76 | In-house | 176-278 (278) | Show / Hide |
Range on Protein: 182-264 Range on HMM: 176-278/278 Sequence Identity: 28% (29 aa) PPEYLV---ANS-YSAAADFWDLGIFLYYCVVGGSPFPM----DNKETITGMIVAY-----P--NFLSQSIIDLFKKLITASPAHRYN-----TRDIKEH .|| | .. ...|.| | ||. .| .| .|| . . ||... . . | ..||| || .|. . |. |.. . .||.| APEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQH PWF ||| PWF |
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Kinase | 97483.m00096.AA | AMPK | 230-264 | 42 | 1.3e-10 | 27.81 | In-house | 220-254 (254) | Show / Hide |
Range on Protein: 230-264 Range on HMM: 220-254/254 Sequence Identity: 42% (15 aa) PNFLSQSIIDLFKKLITASPAHRYNTRDIKEHPWF | |||... || |.. . | |.. ||..|||| PKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF |
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Kinase | 97483.m00096.AA | Ciliate-E2b | 191-264 | 23 | 1.7e-09 | 25.16 | In-house | 187-272 (272) | Show / Hide |
Range on Protein: 191-264 Range on HMM: 187-272/272 Sequence Identity: 23% (20 aa) YSAAADFWDLGIFLYYCVVGGSPF------PMDNKETITGM--IVAYPNFLSQSII--DLFKKLITASPAHRY--NTRDIKEHPWF |. ..| | .||.|| .|. |. | . |. . .|.... . .| .. .| | | |||| YTYKVDIWSVGICLYEFMCGYVPWAEDVQDPYEIYQEIIKKYDEIQFPSYCKDKMADKKLMLQCLQKMPEVRLGGSYSWLKSHPWF |
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Kinase | 97483.m00096.AA | Ciliate-E2 | 36-140 | 15 | 1.2e-07 | 22.32 | In-house | 45-187 (365) | Show / Hide |
Range on Protein: 36-140 Range on HMM: 45-187/365 Sequence Identity: 15% (22 aa) VTSQEVSIKVYSKKFLAIDNNKEYFE----------NDLYCLKTFFHPFIAKYITKLE--DSKFVYIVLEPMRGGTFKELLEAKTRW-----------NE |..... .|...|. . . ..... | . |.. ||.| |.. . | . .|.|.| ||. ..... . . .| VKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTE AQARPYFAQLYF---------------IIEYMQTQMNMIHGNL ... ...|. .||. . | || .. KEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDI |
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Kinase | 97483.m00096.AA | Pkinase | 182-264 | 20 | 3.8e-07 | 26.37 | Pfam | 179-293 (293) | Show / Hide |
Range on Protein: 182-264 Range on HMM: 179-293/293 Sequence Identity: 20% (23 aa) PPEYLV-ANSYSAAADFWDLGIFLYYCVVGGSPFPMD------NKETITGMIVAYPNFLS-------------------------QSIIDLFKKLITASP .|| . .. |. ..| | .|. ||. . | ||| . .. . .| |. . .. .|. |.... | APEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDP AHRYNTRDIKEHPWF . |.. ..|..|||| KKRPTAEQILQHPWF |
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Kinase | 97483.m00096.AA | Ciliate-E2b | 67-158 | 22 | 6.9e-07 | 17.15 | In-house | 54-146 (272) | Show / Hide |
Range on Protein: 67-158 Range on HMM: 54-146/272 Sequence Identity: 22% (21 aa) LKTFFHPFIAKYITKLEDSKFVYIVLEPMRGGTFKELLEAKT--RWNEAQARPYFAQLYFIIEYMQTQMNMIHGNLCLDILMVDENNVIRCVDF |.. |||| |.| |....| ..| .|. . ... .. ... |.|.. ..|| . . | |.. . |||.. .. .|. LEKCNHPFIMKFIRSFKDDQHMYFMMEFCNGMELFDVIREIGRLLLSTYDSQFYIASICLCLEYLH-NQNIIYRDIKPENIMVDHKGYMKLIDM |
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Kinase | 97483.m00096.AA | AMPK | 32-158 | 26 | 9.6e-07 | 16.12 | In-house | 18-144 (254) | Show / Hide |
Range on Protein: 32-158 Range on HMM: 18-144/254 Sequence Identity: 26% (34 aa) AHHSVTSQEVSIKVYSKKFLAIDNNKEYFENDLYCLKTFFHPFIAKYITKL-EDSKFVYIVLEPMRGGTFKELLEAKTRWNEAQARPYFAQLYFIIEYMQ . | |...| ||. |. .. . .| .. . || | || | . . | . ..|.| || . ..| .| .|. .|.| .||. GTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQEREACRFFQQIISGVEYCH TQMNMIHGNLCLDILMVDENNVIRCVDF . . | | . | |.|. | ||| -RHMIVHRDLKPENLLLDHNKNIKIVDF |
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Kinase | 97483.m00096.AA | CAMKL | 32-122 | 24 | 7e-06 | 14.53 | In-house | 18-136 (297) | Show / Hide |
Range on Protein: 32-122 Range on HMM: 18-136/297 Sequence Identity: 24% (29 aa) AHH-SVTSQEVSIKVYSKKFLAIDNNKEYF------ENDL------YCLKTFF---HPFIAKYITKLEDSKF------VYIVLEPMRGGT--FKELLEAK |.| . | ..| ||.. || . | ... | |. ..| . || | | .|.... .|.|.| || . .... ATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKH ----TRWNEAQARPYFAQL | | .|| || |. GHRRGRMPEHEARRYFRQI |
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Kinase | 97483.m00096.AA | RSK | 72-129 | 24 | 2.4e-05 | 15.92 | In-house | 60-120 (278) | Show / Hide |
Range on Protein: 72-129 Range on HMM: 60-120/278 Sequence Identity: 24% (15 aa) HPFIAKYITKLEDSKFVYIVLEPMRGGTFKELLEAKTR---WNEAQARPYFAQLYFIIEYM |||| .. .. . .|...| .||| . . |. . . . | |. |.|.. .|.. HPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHL |
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Kinase | 97483.m00096.AA | AGC | 72-137 | 26 | 3.1e-05 | 7.92 | In-house | 83-177 (395) | Show / Hide |
Range on Protein: 72-137 Range on HMM: 83-177/395 Sequence Identity: 26% (26 aa) HPFIAK----YITK-L----EDSKF--VYIVLEPMR---------GG-TFKELLE---AKTRWNEAQARPYFAQ-------LYFIIEYMQTQMNMIH || | | .|.| | .| . .|.|.| | || . | . | .| .|| |.|. . .||. .|. || HP-I-KSHHPFIVKILHYSFQDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIH |
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Kinase | 97483.m00096.AA | Pkinase | 32-122 | 20 | 0.004266 | 12.03 | Pfam | 18-117 (293) | Show / Hide |
Range on Protein: 32-122 Range on HMM: 18-117/293 Sequence Identity: 20% (20 aa) AHHSVTSQEVSIKVYSKKFLAIDNNKEYFE-NDLYCLKTFFHPFIAKYITKLEDSKFVYIVLEPMRGG----TFKELLE--AKTRW--NEAQARPYFAQL .|| |...| .|. .|. . ... . . .. .| . ||.| ... ||.. .|.|.| ..|| ..... .... | ... |. |. CHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQI |