Gene 95978.m00076 (T.vaginalis)

95978.m00076

Species: T.vaginalis
Alias: 95978.m00076, TvagK0345
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
95978.m00076.AA Protein None 966 None Fasta, JSON
95978.m00076.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of 95978.m00076.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 95978.m00076.AA TKL 126-372 21 6.3e-62 212.05 In-house 1-364 (364) Show / Hide 
Range on Protein: 126-372
Range on HMM: 1-364/364
Sequence Identity: 21% (81 aa)

IGHGGFGEVWLANDLR--------TGKIVAIKELFAEKLVGRNL-------------------------TNFVREIVTMGKCKDRFIIPFIGYTVEKP--
|| ||||||. ..           ||| ||.| .  .    ...                           ...||. | ...   |..|.||  . |  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------YCIITEYMPNGALSSYLRKEFRAKPIFSGTHLTM-IAMGLIFAIRHVHIQK--------IIHRDIKAANLLLDHHFL-----------
            .||..||.|.| | .||             |... .|..   .. . | ..        |||||.| .|.|.| ..            
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNA

---PKLCDFGISRFIKRK---------------------IMTDAIGTASHMAPEIMVST----------------KYDIKVDVFAYGATLFEMVEKKNPF
   .|.||||.|||....                          .||  .||||..  .                .|. |.||...|  |.|..  . |.
DWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPY

AGHPMKEVI---------NNIRT-GKRPIFR-----------RQDTPECLINLIGRCWAQNPKQRPTSDEIYKEF
...|. ..|           .   |.||                |.|. ...|. .||...|..||. .|| |..
YDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Pkinase 95978.m00076.AA Pkinase 120-372 24 1.6e-59 208.86 Pfam 1-293 (293) Show / Hide 
Range on Protein: 120-372
Range on HMM: 1-293/293
Sequence Identity: 24% (72 aa)

FVFQEIIGHGGFGEVWLANDLRTGKIVAIKELFAEKLVGRNLTNFVR--EIVTMGKCKDRFIIPFIGYTV-EKPYCIITEYMPNG----ALSSYLRKEFR
... ..|| |.||.|... .  ||||||.|..  ..     . . .|  ||  | ...  .|. ....   .. .....||...|     |..|..   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--W

AKPIF--SGTHLTMIAMGLIFAIRHVHIQKIIHRDIKAANLLLDHHFLP----KLCDFGISR---FIKRKIMTDAIGTASHMAPEIMV-STKYDIKVDVF
..  |  |  .. ...  .. .. . | ..|||||.| .|.|.|..  .    |.||||...     .   ||.  ||   ||||.   ...|. |||..
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

AYGATLFEMVEKKNPFAGH------PMKEVINNIRTGKRPIFRRQDTP-------------------ECLINLIGRCWAQNPKQRPTSDEIYKE--F
..| .|.||. .. || ||       ....|..|. .. .  . .. .                   | .. .| .|....||.||| ..| .   |
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
S_TKc 95978.m00076.AA S_TKc 120-373 26 3.9e-58 200.35 SMART 1-231 (231) Show / Hide 
Range on Protein: 120-373
Range on HMM: 1-231/231
Sequence Identity: 26% (70 aa)

FVFQEIIGHGGFGEVWLANDLRTGKIVAIKELFAEKLVGRNLTNFVREIVTMGKCKDRFIIPFIGYTVEKPYCIITEYMPN--GALSSYLRKEFRAKPI-
. . ..||.|.||.|... . .||.|||||..           .. |||  . | .  .|. .... ... .....||...  | | .|..|  | ..  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-FSGTHLTMIAMGLIFAIRHVHIQKIIHRDIKAANLLLDHHFLPKLCDFGISRFIKRKIMTDAIGTASHMAPEIMVSTKYDI-KVDVFAYGATLFEMVEK
 |.  |   ..  .. |. . | ..|||||.| .|.|||.    |.||||..|..     |  .||   ||||..   .|.  |.|. . | .|.||.  
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCG

KNPFAGHPMKEVINNIRTGKRPIFRRQDTPECLINLIGRCWAQNPKQRPTSDEIYK--------EFA
. ||    |......|.            .. ....| .|.  .|..|||  |. .        .. 
YPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 95978.m00076.AA STE 120-373 20 8.4e-49 168.45 In-house 1-359 (359) Show / Hide 
Range on Protein: 120-373
Range on HMM: 1-359/359
Sequence Identity: 20% (75 aa)

FVFQEIIGHGGFGEVWLANDLR---------------TGKIVAIKEL-FAEKLV--------------GRNLTNFVREIVTMGKCK--DRFIIPFIGYTV
. ..|.||.|.||.| .| .                 ||.|.|||.. . ..                  .. .. .|| .| ||.    .|. ..|. .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

EKP--------YCIITEYMPNGALSSYLRKEFRAKPIFS----------GTHLTMIAMGLIFA-IRHVHIQKIIHRDIKAANLLLDHHFLPKLCDFGISR
 .          .|. |||..| |.. ... .  .  ..           . .  |.  .. .   . | ..|||||||.|| ||      ||||||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

FIKR------------------KIMTDAIGTASHMAPEIMVS------TKYDIKVDVFAYGATLFEMVEKKNPFAG-HPMKEVINNIRT-----------
 .                    .  .  .||  .||||..         .||.|.|.   | |. ||.. | |..  |||.   . ..            
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---GKRPIFRRQDTP------------------ECLINLIGRCWAQNPKQRPTSDEIYK---EFA
   |. | .     .                  ..... | .|   .|..|||...  |   .| 
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 95978.m00076.AA MLK 120-372 27 1.5e-48 166.57 In-house 1-291 (291) Show / Hide 
Range on Protein: 120-372
Range on HMM: 1-291/291
Sequence Identity: 27% (81 aa)

FVFQEIIGHGGFGEVWLANDLRTG---KIVAIKELFAEK----LVGRNLTNFVREIVTMGKCKDRF----IIPFIGYTVEK-P-YCIITEYMPNGALSSY
. |.|.||.|.||.||...   .    ||||.|. .|..      .    .| .|.    . . .     ||.| |   .  . .||..||...| |...
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LRKEFRAKPI-----------FSGTHLTMIAMGLIFAIRHVHIQK---IIHRDIKAANLLLDH------HFLPKLCDFGISRFIKRK-I-MTDAIGTASH
|. . | |.             .  |.  .|.    ..   | ..   |||||.|  |.|.|.      |   | ||||.||.....   |....||.  
LHGA-RSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAW

MAPEIM---VSTKYDIKVDVFAYGATLFEMVEKKNPFA-GHP-MKEVINNIRTGKRPIFRRQDTPECLINLIGRCWAQNPKQRPTSDEIYKEF
||||.     ..||..|.||. .|  | ||. .. |.. ..  |   . .. .|.||  . .  || . .|. .|| |.|..||....| ...
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPST-CPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase 95978.m00076.AA TyrKc 120-372 25 4.9e-44 153.54 SMART 1-280 (280) Show / Hide 
Range on Protein: 120-372
Range on HMM: 1-280/280
Sequence Identity: 25% (74 aa)

FVFQEIIGHGGFGEVWLANDLRTGKIVAIKELFAEKLVGRNLTNFVREIVTMGKC--KDRFIIPFIGYTVE--------KPYCIITEYMPNGALSSYLRK
 .. ...|.| ||||...  ..    ||.| | ...     .  | ||.  | |   .   |. ..|. ..        .|..|..||||.|.| .||||
ITLGKKLGEGAFGEVYKG-TWK--IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

EFRAKPIFSGTHLTMIAMGLIFAIRHVHIQKIIHRDIKAANLLLDHHFLPKLCDFGISRFIKRK----IMTDAIGT----ASH-------MAPEIMVSTK
  .    ..  .|  ..       .. | ...||||. | | |... .  | .||| ||.|. .      .| . .     ..       |||| .   |
HRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

YDIKVDVFAYGATLFEMVEK-KNPFAG-----HPMKEVINNIRTGKRPIFRRQD-------TPECLINLIGRCWAQNPKQRPTSDEIYKEF
. .| ||...| ...|.    . |  |      . .|||.....|.|.     |        |. . ... .||. .|..|||  ||...|
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 95978.m00076.AA TK 120-372 14 4.8e-42 138.26 In-house 1-486 (486) Show / Hide 
Range on Protein: 120-372
Range on HMM: 1-486/486
Sequence Identity: 14% (71 aa)

FVFQEIIGHGGFG---EVWLA------------------------NDLRTGK-IVAIKELF--AEKLVGRNLT-------------NFVREIVTMG--KC
 .. . .|.| ||   ||...                        |. . ||  ||.| |   ..    . .              ....|.  |   ..
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

KDRFIIPFIGYTVEK-------------PYCIITEYMPNGA----LSSYLR--KEFRAK-----------------------------------------
.   |. ..|. ...             |..|..||||.|     | .|||  .. . .                                         
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

---------PIFSGTHLTM-------------------IAMGLIFAIRHVHIQ------KIIHRDIKAANLLLDHHFL-----------PKLCDFGISRF
         | .. ..|                     ... .  . .. | .      ...|||. | | |....              |..||| || 
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

IK----RKIMTDAIGTASH--------------------------------MAPEIMVSTK---------YDIKVDVFAYGATLFEMVE--KKNPFAGHP
      |.|  |   ....                                |||| . . .         . .| ||...| ...|..   .. .  |..
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS

M---------KEVINNIRTGKRP----------IFRRQDTPECLI-----------------NLIGRCWAQNPKQRPTSDEIYKEF
          .||....|.| |.           .|.   | |                    |. .||. .|..||| .......
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase 95978.m00076.AA Dicty5 143-376 33 4.5e-41 139.11 In-house 22-260 (260) Show / Hide 
Range on Protein: 143-376
Range on HMM: 22-260/260
Sequence Identity: 33% (80 aa)

GKIVAIKELFAEKLVGRNLTNFVREIVTMGKCK---DRFIIPFIGYTVEKPY-CIITEYMPNGALSSYLRKEFR--AKPIFSGTHLTMIAMGLIFAIRHV
|. ||||..  |  .. ..  | ||.  |   .   . ||  .   . .. |  ..|||  || |..||.   .   .||  .. | | |..   ..||.
GMDVAIKVYSQENCMCFDWNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQPIAYFQQLHM-AIDIAQSMRHL

HIQKIIHRDIKAANLLLDHHFLPKLCDFGISRFIK-RKIMTDAIGTASHMAPEIMVSTKYDIKVDVFAYGATLFEMVEKKNPFAGHPMKEVINNIRTGKR
|   |||||.|  | |.   .  |. |||.|||.  |. ||  .||   ||.|.  .  |. |.||...|  |.||  .| |.      .  . .  | |
HSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGIVLWEMFTRKEPYDNINNWNIPVMVMKGER

PIFRRQDTPECLINLIGRCWAQNPKQRPTSDEIYKEFATGK
|     | |    |||  || | |..||.  || | |    
PTIP-KDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII
Kinase 95978.m00076.AA Ciliate-E2 120-370 18 4.3e-40 135.32 In-house 1-361 (365) Show / Hide 
Range on Protein: 120-370
Range on HMM: 1-361/365
Sequence Identity: 18% (69 aa)

FVFQEIIGHGGFGEVWLANDLRTGKIVAIK-----------------ELFAEKLVGRNLTNFVREIVTMGKCKD-----------------RFIIPFIGY
. |...|| |.|| |..... ...| .|||                  ..| | .  |  ...  .  . ....                  .|| .. .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

TV---EKPYCIITEYMPNGALSSYLR----------------KEFRAKPIFSGTHL------TMIAMGLIFAIRHVHIQK-IIHRDIKAANLLLDHHFLP
     .. . ...||   | | .|..                .|. .| |.            ...  .| |... | .. |||||||  |.|.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLCDFGISRFIK-----------RKIMTDAI-----------------------GTASHMAPEIMVSTK---------YDIKVDVFAYGATLFEMVEKKN
|..|||.|....           .|....                         ||.  |||||  . |         || |.|... | .|.||. .| 
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFAGHPMKEVINNIRTGKRPIF----------------RRQDTPECLINLIGR----CWAQNPKQRPT-SDEIYK
||        ...|  .|  ..                  .. ..  ..|| .    .   .|..|.|  ..| .
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN
Kinase 95978.m00076.AA Ciliate-E2-Unclassified 120-370 19 2.5e-38 130.53 In-house 1-348 (352) Show / Hide 
Range on Protein: 120-370
Range on HMM: 1-348/352
Sequence Identity: 19% (68 aa)

FVFQEIIGHGGFGEVWLANDLRTGKIVAIKELF-----AEKLVGRNLTNFVREIVTMGK-------------------CKDRFIIPFIGY-TVEKPYCII
. ....||.||||.|... .  .... |.|..      . |.. ..  ....|. .| .                   ... ||. .. . . ..  .|.
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

TEYMPNGALSSYLRK-EF------------RAKPIFSGTHLT-----MIAMGLIFAIRHVHIQK-IIHRDIKAANLLLDHH---FLPKLCDFGISR----
.||...| |. |..| ..            . . ||.  .        ..  .. .. . | .. |||||||  |.|.|     . .|..|||||.    
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

-------------FIKRKIMTDAIGTASHM----APEIMVSTKYD----IKVDVFAYGATLFEMVEKKNPFAG-HPMK---------------EVINNIR
             ..|...|.. .|| . |    |||.. . .||    .|.|... |  |.||.  . || .    .               ....|| 
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

TGKRPIF---------RRQDTPECLIN-LIGRCWAQNPKQRPTSDEIYK
 ..  ..         . ... . .|| |. ..   ||..|.| ..| .
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILN
Kinase 95978.m00076.AA Dicty4 241-374 32 7.5e-36 117.17 In-house 135-277 (277) Show / Hide 
Range on Protein: 241-374
Range on HMM: 135-277/277
Sequence Identity: 32% (47 aa)

IIHRDIKAANLLLDHHFLPKLCDFGISRFIKRKI-MTD----AIGTASHMAPEIMVSTKYDIKVDVFAYGATLFEMVEKKNPFA--GHPMKEVINNIRT-
|||||.|..||| | ..  | ||||.|. .|. .  .|    |.||.  ||||.|..  |. |.||. .|  |.|.. .. |..  . |  .... .   
IIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNK

GKRPIFRRQDTPECLINLIGRCWAQNPKQRPTSDEIYKE--FAT
. ||.   ...|  .. || .||  .|..||.  || ..    .
KLRPPI-PDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase 95978.m00076.AA LRRK 189-374 28 7.2e-35 120.79 In-house 128-351 (351) Show / Hide 
Range on Protein: 189-374
Range on HMM: 128-351/351
Sequence Identity: 28% (63 aa)

KPYCIITEYMPNGALSSYLRKEFRAK-----PIFSGTHLTMIAMGLIFAIRHVHIQK--IIHRDIKAANLLL---D---------HHFLPKLCDFGISR-
.|.|...||.|.|.|...|..... .     . .| . .  ||.    .... | ..  ||||| |  | ||   .          |   |..|||||| 
HPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRM

-FIKRK-IMTDAIGTASHMAPEIMVST---KYDIKVDVFAYGATLFEMVEKK-NPFAGHP-------MKEVINNIRTGKRPIFRRQD-TPE-----CLIN
 .. .. .  .  |.   ||||||  .    |. |||....|  |.| .  .  || .|.       | .. ..|  | || .  |.  |.     .. .
FQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIEDKIIEGLRPTIP-QHYCPPCQPWHMYQD

LIGRCWAQNPKQRPTSDEIYKEFAT
||  ||...||.||.. .| |   .
LIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase 95978.m00076.AA TKL-Unique 237-372 28 1.3e-30 105.19 In-house 128-290 (290) Show / Hide 
Range on Protein: 237-372
Range on HMM: 128-290/290
Sequence Identity: 28% (46 aa)

HIQK-IIHRDIKAANLLLDHH-----FLPKLCDFGISRFIKRKIMTDAI-----------GTASHMAPEIMVS--TKYDIKVDVFAYGATLFEMVEKKN-
| .. |||||.|  |.|.| .     .  |.||||.|.| .. . . ..           |..  ||||.. .  ..|..|.||...|. | |... |  
HCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSEKSDVYSFGIVLWEIATRKIT

-----PFAGHPMKEVINNIRT---GKRPIFRRQDTPECLINLIGRCWAQNPKQRPTSDEIYKEF
     |. |   ....  ...   ..||    .. |. . .|| .||...| |||. |||... 
KTYKKPYQGMDQEQWCEMVHYMEENYRPPIP-NHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase 95978.m00076.AA Pkinase_Tyr 239-372 28 3.7e-20 68.91 Pfam 130-270 (270) Show / Hide 
Range on Protein: 239-372
Range on HMM: 130-270/270
Sequence Identity: 28% (42 aa)

QKIIHRDIKAANLLLDHHFLPKLCDFGISRFIKRKIMTDAIG-TASH--------MAPEIMVSTKYDIKVDVFAYGATLFEMVE-KKNP-FAGHPMKEVI
...||||. | | |... .  | |||| .| |    . |    ....        |||| .   |. .| || ..| ...|..   . | ..| .  ||.
KNCIHRDLAARNCLVTENNVVKICDFGLARDI----YNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVY

NNI-RTGKRPIFRRQDTPECLINLIGRCWAQNPKQRPTSDEIYKEF
. | . | |   . ...|. . .|. .||...|..|||  ||. ..
EYIYEDGYR-MPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase 95978.m00076.AA Pkinase_Tyr 120-209 30 1.8e-16 56.42 Pfam 1-100 (270) Show / Hide 
Range on Protein: 120-209
Range on HMM: 1-100/270
Sequence Identity: 30% (31 aa)

FVFQEIIGHGGFGEVWLANDL----RTGKIVAIKELFAEKLVGRN--LTNFVREIVTMGKC-KDRFIIPFIGYTV--EKP--YCIITEYMPNGALSSYLR
 .| . .|.| ||||...        |.  ||.| |  |.   ..  .  | ||. .| .  .   |. ..|  .  ..|  ..|..||||.| | .|||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

K
|
K
Kinase 95978.m00076.AA TKL-Unique 122-207 31 2.2e-09 29.43 In-house 1-91 (290) Show / Hide 
Range on Protein: 122-207
Range on HMM: 1-91/290
Sequence Identity: 31% (29 aa)

FQEIIGHGGFGEVWLANDLRTGKIVAIKELFA-EKLVGRNLTNFVREIVTMGKCK-DRFIIPFIGYTV----EKP-YCIITEYMPNGALSSYL
| . || ||.|.|  .     |..|||| ..  |..  . . .| .|. .| | .   .|  ..||..      | .||..||.| | | ..|
FWNKIGEGGYGQVYKG--KWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVL
Kinase 95978.m00076.AA Dicty4 120-210 32 1.9e-08 24.49 In-house 1-102 (277) Show / Hide 
Range on Protein: 120-210
Range on HMM: 1-102/277
Sequence Identity: 32% (34 aa)

FVFQEIIGHGGFGEVWLANDLRTGKIVAIKELFAEKLV--GRNLTNFVREIVTMGKCKDRFIIPFIGYTV---EKP--YCIITEYMPNGALSSYLRK---
 .....|| |.|||| ...  | ||.||.| |.. . .     |. | .|.  |.|     |. | |.      .|   || ||||| | | | |..   
INIEQRIGKGSFGEVYKGT-WR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPS

---E
   .
EQQQ
Kinase 95978.m00076.AA LRRK 120-134 50 0.010288 5.41 In-house 1-16 (351) Show / Hide 
Range on Protein: 120-134
Range on HMM: 1-16/351
Sequence Identity: 50% (8 aa)

FVFQEIIGHGGFG-EV
....| || |||| .|
LKIEEQIGRGGFGTFV