Gene 88601.m00465 (T.vaginalis)

88601.m00465

Species: T.vaginalis
Alias: 88601.m00465, TvagK0594
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CRK7-like

Sequence

Name Sequence Type Origin Length Description Download
88601.m00465.AA Protein None 360 None Fasta, JSON
88601.m00465.kin_dom Protein Kinase Domain None 293 None Fasta, JSON

Protein domain

Protein domains of 88601.m00465.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 88601.m00465.AA CDK 18-310 35 9.80000000001e-108 345.79 In-house 1-284 (284) Show / Hide 
Range on Protein: 18-310
Range on HMM: 1-284/284
Sequence Identity: 35% (114 aa)

FTKVEKIGLGTYGKVYKCLDIRKK-----QTVALKKIKILK-----PNDGFPVNTVREIKCLKELKHDNIIRLRNVITLYKPNKP------STVWLSFDY
. |.|||| ||||.|||. | . .     | ||||||.. .       .|||  ..|||..|||| |.||..|. |..  .. .       ..... |.|
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

CEFDLFGLLHKTDFPQLSTKQVLCYSRQLILAMLQCKQAEILHRDLKPANLFITRDNV-----LKIGDFGLARKFKS------DDIKYTYNVITLYYRAP
.. || ....           . || .||. ..  | .  |.||||||.|. |... .     |||.||||||.| .         .|| .|.|| ||||
MDHDLKKYMD-----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAP

ELILGCQNYQ--YEVDVWSVGCILYELCT---NKYFFKAPIGKEIDQLTAIFKITGTPDNEEWPEFKELDKGGLFTQKIEGNLLEYLEKTIPPEFEGAAD
|| ||...|    ..|.||||||..|. |   .|..|      |||||  ||.| |||. . ||....|                              |
ELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPG--DSEIDQLFKIFRICGTPTEDNWPGVTKLPDY---------------------------D

LISKMCRLTPSKRISMQEAFMHPFI
|..||  . |.|||| ..|  ||. 
LLNKMLCYDPKKRISAEQALQHPYF
Kinase 88601.m00465.AA CDC2 18-310 38 7.79999999999e-103 316.91 In-house 1-301 (301) Show / Hide 
Range on Protein: 18-310
Range on HMM: 1-301/301
Sequence Identity: 38% (119 aa)

FTKVEKIGLGTYGKVYKCLDIRKKQTVALKKIKILKPNDG--FPVNTVREIKCLKELK-HDNIIRLRNVITLYKPNKPSTVWLSFDYCEFDLFGLLHKTD
..|.|||| ||||.|||| | . .| ||||||..   ..|  .|  ..||| |||||| |.||..|. ||        . . . |.|...||  .. .  
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ------NKLYMVFEYLDMDLKKYMDMSI

FP--QLSTKQVLCYSRQLILAMLQCKQAEILHRDLKPANLFITRDNVLKIGDFGLARKFKSDDIKYT--YNVITLYYRAPELILGCQNYQYEVDVWSVGC
 .  ...   |  |  |.. ..  | |  |.|||||| |..| .. ..||.|||||| |     .||   .|.|| |||||. |||. |  .||.||.||
PKNKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGC

ILYEL---CTNKYFFKAPIGK-EIDQLTAIFKITGTPDNEEWPEFKELD-KGGLFTQKIEGNLLEYLEK-----TIPPEFE-GAADLISKMCRLTPSKRI
|..|.   .|.|..|   .|. |||||  ||.| |||....||. ..|      | .  . .| .....         . .  . ||...| .. |.|||
IFAEMFMDVTKKPLF---HGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNTFPRWKPQDLSKICPNNQKKKNQ-SCLDPEGIDLLMQMLQYDPQKRI

SMQEAFMHPFI
| .||  ||..
SAKEALQHPYF
Kinase 88601.m00465.AA CMGC 18-310 22 1.4e-98 324.55 In-house 1-513 (513) Show / Hide 
Range on Protein: 18-310
Range on HMM: 1-513/513
Sequence Identity: 22% (114 aa)

FTKVEKIGLGTYGKVYKCLD--------------IRKKQTVALKKIKILKPND----------GFPVNTVREIKCLKELK-----------------HDN
.....||| ||||.|||| |              .. .. ||.||||  . ..          |||  . ||||.||.|.                 | |
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IIRLRNVITLYKPNKPS------------TVWLSFDYCEFDLFGLLHKTDFP-------QLSTKQ------------VLCYS------RQLILAML--QC
|..|.....  .....              . | |.|.. ||....... |.        ||  .            . ...      .|.. ..    |
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

KQAE--ILHRDLKPANLFITRDNVL--------------------KIGDFGLARKFKSDDIK---------------------YTYNVITLYYRAPELIL
 ..   |.||||||.|. |. .. |                    ||.||||||.. . . .                     || .| |..|||||..|
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

GC---------QNYQYEVDVWSVGCILYELCTN--------KYFFK----APIGKE-------IDQLTAIFKITGTPD---------------NEEWPEF
|.         ..| ...|.||||||..|. |.        |..|.     |.  .       ||||  |||. |||.                ||||..
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPN--DDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNM

KELDKGGLFTQ--------------------------KIEGNLLEYLEKTIPP--------------------------------EFEGAADLISKMCRL
..|.   .| .                          .. .. .. |.. .|.                                . . | ||..|| ..
IKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQY

TPSKRISMQEAFMHPFI
 |.|||. ..|  ||..
DPDKRITAEQALQHPYF
Kinase 88601.m00465.AA S_TKc 18-310 26 5.7e-83 282.88 SMART 1-231 (231) Show / Hide 
Range on Protein: 18-310
Range on HMM: 1-231/231
Sequence Identity: 26% (83 aa)

FTKVEKIGLGTYGKVYKCLDIRKKQTVALKKIKILKPNDGFPVNTVREIKCLKELKHDNIIRLRNVITLYKPNKPSTVWLSFDYCEF---DLFGLLHKTD
.....||| |..|||||| ... .. ||.|.||          .. |||..||. .|.||..|  |.        . ... ..||.    ||| ...|  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD------DHLYMVMEYCDGDLGDLFDYIKKRG

FPQ----LSTKQVLCYSRQLILAMLQCKQAEILHRDLKPANLFITRDNVLKIGDFGLARKFKSDDIKYTYNVITLYYRAPELILGCQNYQY-EVDVWSVG
 .     ..  .. .| .|...|.  | .  |.||||||.|.....  ..||.||||||..       |  . |..|.|||..     | . ..|.||.|
RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCG

CILYELCTNKYFFKAPIGKEIDQLTAIFKITGTPDNEEWPEFKELDKGGLFTQKIEGNLLEYLEKTIPPEFEGAADLISKMCRLTPSKRISMQEAFM---
|||||... .  |         |. ..||. |                                       . | |.|.|...  |.||..  ||.    
CILYEMLCGYPPFP--------QMQMMFKKIG--------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEW

----HPFI
    ||..
DIKCHPWF
Kinase 88601.m00465.AA CRK7 18-310 32 5.2e-79 268.81 In-house 1-343 (343) Show / Hide 
Range on Protein: 18-310
Range on HMM: 1-343/343
Sequence Identity: 32% (112 aa)

FTKVEKIGLGTYGKVYKCLDIRKKQTVALKKIKILKP---NDGFPVNTVREIKCLKELKHDNIIRLRNVITLY-----KPNKPSTVWLSFDYCEFDLFGL
. ... || ||||.|||  . . .. |||||..        .|||.  .|||| |..|.|.||..|. ..|       . ..  .... |.|   || ||
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQLNHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDLMGL

LHKTDFPQLSTKQVLCYSRQLILAMLQCKQAEILHRDLKPANLFITRDNVLKIGDFGLARKFKSDD--IKYTYNVITLYYRAPELILGCQNY--------
|   .. . |  |. |. .|| . |  | .  .||||.| .|. .     .|| ||||||.. |..   .||  |||| ||.||| || ..|        
LESKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHILKE

------------------------------QYEVDVWSVGCILYELCTNKYFFKAPIGKEIDQLTAIFKITGTPDNEEWPEFKELDKGGLFTQKI--EGN
                                |.|.||.|||| || | |  |..    |..||  |.|| |.|  . |||  .|     . .|   .  
LIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQG--NNEMAQLEKIYKICGSPNPNNWPEVMKLPWWNTMKPKRQYNRR

LLEYLE---K--TIPPEFEGAADLISKMCRLTPSKRISMQEAFMHPFI
|.|  .   |   .|.|   . ||  ||  | |.||.. .|.  |...
LREEFYHHKKPVFMPKE---CLDLLDKMLCLDPKKRFTAEECLQHDWF
Kinase 88601.m00465.AA CDK5 18-310 35 4.7e-74 233.25 In-house 1-287 (287) Show / Hide 
Range on Protein: 18-310
Range on HMM: 1-287/287
Sequence Identity: 35% (106 aa)

FTKVEKIGLGTYGKVYKCLDIRKKQTVALKKIKILKPNDGFPVNTVREIKCLKELKHDNIIRLRNVITLYKPNKPSTVWLSFDYCEFDLFGLLHKTDFPQ
. |.|||| |||| ||| ..   .  ||||....     | |   .|||  |||||| ||.||  ||     .|     | | .|  ||   . .    .
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVI--HSEKK---LTLVFEFCDQDLKKYMDSCNG-E

LSTKQVLCYSRQLILAMLQCKQAEILHRDLKPANLFITRDNVLKIGDFGLARKFKSDDIKYTYNVITLYYRAPELILGCQNYQYEVDVWSVGCILYELC-
.. . .  .  ||   .  | . ..||||||| || | .   || .|||||| |      |.  |.|| ||.|   .| . |   .|.||.|||. |.  
MDMHIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMAN

TNKYFFKAPIGKEIDQLTAIFKITGTPDNEEWPEFKELDKGGLFTQKIEGNLLEY-LEKTIPPEFEGAADLISKMCRLTPSKRISMQEAFMHPFI
. .  |  |   . |||  ||||.|||  ..||   .| .     |. .   ..  ... .|   |   || .|| .. | .||| ..| .||. 
AGRPLF--PGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase 88601.m00465.AA Pkinase 18-310 28 7.5e-74 256.46 Pfam 1-293 (293) Show / Hide 
Range on Protein: 18-310
Range on HMM: 1-293/293
Sequence Identity: 28% (89 aa)

FTKVEKIGLGTYGKVYKCLDIRKKQTVALKKIKILKPNDGFPVNTVR--EIKCLKELKHDNIIRLRNVITLYKPNKPSTVWLSFDYCEF-----DLFGLL
.....||| |..|.|||| ..   ..||.|.||  . ....... .|  ||. .|.|.|.||.||. . .      .. ... ..|||      ||| ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-----KDHIYMVMEYCEGGLYVMDLFDYI

H---KTDFPQLSTKQVLCYSRQLILAMLQCKQAEILHRDLKPANLFITRDNVL----KIGDFGLARKF-KSDDIKYTYNVITLYYRAPELILGCQNYQYE
.   .. |  .| ... .| .|.. ..  | .  |.||||||.|..| .....    ||.|||||..|    .  .|  . |..|.|||.|.|.| | ..
STWRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK

VDVWSVGCILYELCTNKYFFKAPI---GKEIDQLTAIFKITGTPDNEEWPEFKE-LDKGGLFTQKIEGNLLEYLEKTIPPEFEGAADLISKMCRLTPSKR
||.||.||||||... .  |.       . .||.  |..| |.|  ..||.  .  .   ... . .    . ...  .   | . |.|...... |.||
VDMWSCGCILYEMLCGRPPFP-GHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H----F-HWTF-HNWSEECKDFIKWCLCKDPKKR

ISMQEAFMHPFI
.. .... ||..
PTAEQILQHPWF
Kinase 88601.m00465.AA PITSLRE 18-310 35 4e-69 235.96 In-house 1-295 (295) Show / Hide 
Range on Protein: 18-310
Range on HMM: 1-295/295
Sequence Identity: 35% (109 aa)

FTKVEKIGLGTYGKVYKCLDIRKKQTVALKKIKIL--KPNDGFPVNTVREIK-CLKELKHDNIIRLRNVITLYKPNKPSTVWLSFDYCEFDLFGLLHKTD
| .. .|. |||| ||.  | |.   ||||..|.   |  .|||.  .|||.  |..|.|.||. .. ..     .|   ... ..| | || .|. .  
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVNVKEIVMGSNMDK---IYMVMEYVEHDLKSLMENMK

--FPQLSTKQVLCYSRQLILAMLQCKQAEILHRDLKPANLFITRDNVLKIGDFGLARKFKSDDIKYTYNVITLYYRAPELILGCQNYQYEVDVWSVGCIL
    . .. .. |   || ...       |.||||| .|| ..   .|||.||||||.. |   .|| .|.|| |||||| |||. |   ||.||||||.
RRNQPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGCIF

YELCTNKYFFKAPIGK-EIDQLTAIFKITGTPDNEEWPEFKELDKGGLFT----QKIEGNLLEYLE--KTIPPEFEGAADLISKMCRLTPSKRISMQEAF
 |. | |  |.   || ||||.  |||  |||    || ..||.   ...    .. ..|| .     ..|    . . ||  .|  . | .||.  .| 
AEFITMKPLFQ---GKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNNFPHYP-YNNLRKRFPAENHIS---DTGFDLLNQMLTYNPKNRITASDAL

MHPFI
 ||. 
KHPWF
Kinase 88601.m00465.AA CDK-DD1 18-249 35 5.7e-65 199.34 In-house 1-225 (379) Show / Hide 
Range on Protein: 18-249
Range on HMM: 1-225/379
Sequence Identity: 35% (85 aa)

FTKVEKIGLGTYGKVYKCLDIRKKQTVALKKIKILKPNDGFP-VNTVREIKCLKELKH-DNIIRLRNVITLYKPNKPSTVWLSFDYCEFDLFGLLHKTDF
.  ..|.| |.||.|.|      . .||||..| .   || | |    |.| |. |.|  ||.   ..|  .  .| |   . | | |.|| ...     
YQIISKCGQGIYGSVFKAIHKITHCMVALKNFKDWNQEDGEPKV----ECKYLMQLRHCKNIV---HLIDHFYNFKNSKYVMVFEYFEHDLWKFMSN---

PQ--LSTKQVLCYSRQLILAMLQCKQAEILHRDLKPANLFITRDNVLKIGDFGLARKFKS-DDIKYTYNVITLYYRAPELILGCQNYQYEVDVWSVGCIL
.|  .|  .. |. .||     .|  . | ||| ||||| |.   .|||.|||..  .    .     .|..|.||.||| .|  .|  |.|.|||||||
HQCYMSLPCIKCFFHQLLEGINECHNQGIMHRDIKPANLLINNRGDLKITDFGFTTYYTKRSEKHFSHQVVSLWYRPPELLMGSCQYGPEIDMWSVGCIL

YELCTNKYFFKAPIGKEIDQLTAIFKITGTPDNEEWP
 |. || |.|  .   |  || .|.|  |.|  . ||
MEMITNFYMF--AGSNEQQQLELICKLCGCPTEKNWP
Kinase 88601.m00465.AA CDK10 18-261 38 1.5e-60 207.46 In-house 1-238 (285) Show / Hide 
Range on Protein: 18-261
Range on HMM: 1-238/285
Sequence Identity: 38% (93 aa)

FTKVEKIGLGTYGKVYKCLDIRKKQTVALKKIKILKPNDGFPVNTVREIKCLKELKHDNIIRLRNVITLYKPNKPSTVWLSFDYCEFDLFGLLHKTDFPQ
| |. ..| |||| ||.  |.| .  |||||... |  || |.  .|||. |....|.||..|. |.     ..   ..|  .||| ||  ||     | 
FEKLNRVGEGTYGIVYRARDMRSDEIVALKKVRMDKEKDGLPISGLREIMLLIQCRHENIVELHEVVV---GQHLDSIFLVMQYCEQDLASLLDNMPQP-

LSTKQVLCYSRQLILAMLQCKQAEILHRDLKPANLFITRDNVLKIGDFGLARKFKSDDIKYTYNVITLYYRAPELILGCQNYQYEVDVWSVGCILYELCT
 .  || |   |.. ..    .  ..||||| .|| .| .  .|. ||||||..       |  ..||.||||||.|||..    .|.| ||||| ||  
FTETQVKCIMLQMLRGLKYLHDNFMIHRDLKVSNLLMTDKGCIKVADFGLARMYGVPVKPMTPKMVTLWYRAPELLLGCRTQTTAIDMWAVGCILGELLV

NKYFFKAPIGKEIDQLTAIFKITGTPDNEEWPEFKELDKGGLFT
.|  .  |   || |.  | .. |||... || | .|   . ||
HKPLM--PGNSEIHQIDMIIDLLGTPSENIWPGFSDLPMVQNFT
Kinase 88601.m00465.AA CDK7 142-254 50 1.4e-49 129.95 In-house 123-233 (288) Show / Hide 
Range on Protein: 142-254
Range on HMM: 123-233/288
Sequence Identity: 50% (57 aa)

ILHRDLKPANLFITRDNVLKIGDFGLARKFKSDDIKYTYNVITLYYRAPELILGCQNYQYEVDVWSVGCILYELCTNKYFFKAPIGKEIDQLTAIFKITG
|||||||| || .  . .|||.|||||| . |    || .|.| .||||||  |   |   ||.||||||. ||     ..  |   .||||| ||.. |
ILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELMLRVPYL--PGDSDIDQLTRIFQTLG

TPDNEEWPEFKEL
||  ||||.  ..
TPTEEEWPNMCCM
Kinase 88601.m00465.AA MAPK 140-246 39 2e-37 126.86 In-house 136-257 (328) Show / Hide 
Range on Protein: 140-246
Range on HMM: 136-257/328
Sequence Identity: 39% (49 aa)

AEILHRDLKPANLFITRDNVLKIGDFGLARKFKS-DDIKY-------------TYNVITLYYRAPELILG--CQNYQYEVDVWSVGCILYELCT-NKYFF
| ..||||||.|. .. .  |||.||||||.. . .  ..             | .| | .|||||..|.   ..|   ||.||||||. |. | .| .|
ANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLF

KAPIGK-EIDQLTAIFKITGTPDNE
.   ||  |||.. |....|||. |
P---GKDYIDQWNLIMEVLGTPSEE
Kinase 88601.m00465.AA CDK7 18-106 36 2.4e-27 69.53 In-house 1-88 (288) Show / Hide 
Range on Protein: 18-106
Range on HMM: 1-88/288
Sequence Identity: 36% (34 aa)

FTKVEKIGLGTYGKVYKCLDIRKKQTVALKKIK-ILKPN---DGFPVNTVREIKCLKELKHDNIIRLRNVITLYKPNKPSTVWLSFDYCEFDL
..|...|| |... ||| .|    | || |||| ..  .   ||     .|||| |.|..|||.| |. ..  .     | . | ||. . ||
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHK-----SNIQLVFDFMDWDL
Kinase 88601.m00465.AA MAPK 18-123 26 4.3e-16 51.95 In-house 1-117 (328) Show / Hide 
Range on Protein: 18-123
Range on HMM: 1-117/328
Sequence Identity: 26% (31 aa)

FTKVEKIGLGTYGKVYKCLDIR------KKQTVALKKIKILKPNDGFPVNTVREIKCLKEL-KHDNIIRLRNVITL------YKPNKPSTVWLSFDYCEF
.. ...|| | || | .. | |      ....||.|||     |  .   | ||||.|... .|.|||.|....|       . . .  .. . ....| 
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

DLFGLLHKTDFPQLSTKQV
||  ...  .  .|| . .
DLHQIIKSQQ--PLSDDHI
Kinase 88601.m00465.AA TyrKc 18-310 21 2.1e-12 -22.12 SMART 1-280 (280) Show / Hide 
Range on Protein: 18-310
Range on HMM: 1-280/280
Sequence Identity: 21% (68 aa)

FTKVEKIGLGTYGKVYKCLDIRKKQTVALKKIKILKPNDGFPVNTVREIKCLKEL--KHDNIIRLRNVITLYKPNKP---STVWLSFDYCEF-DLFGLLH
 |. .|.| | .|.|||.  .   ..||   .| ||..        ||.. ...|  .|.||.||  |.|  . |       ... . |..  ||   |.
ITLGKKLGEGAFGEVYKGTWK---IQVA---VKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN-FMYIEPLMIVMEYMPHGDLKDYLR

KTDFPQLSTKQVLCYSRQLILAMLQCKQAEILHRDLKPANLFITRDNVLKIGDFGLARKFKSD-------DIKYT-----YN-VITLYYRAPELILGCQN
|.    |..|. | .. |    |    .  . ||||   |  ...... ||.||||.|. ..|       | . .      . .. .   ||| |    .
KHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--NYG

-YQYEVDVWSVGCILYELCTNKYFFKAP------IGKEIDQLTAIFKITGTPDN----EEWPEFKELDKGGLFTQKIEGNLLEYLEKTIPPEFEGAADLI
 .  . |||| |  ..|..|.               .|. ..    .    |.|                             .   . |.|     ...
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS------------------------F--VCCPDEM---YQIM

SKMCRLTPSKRISMQEAFMHPFI
.. ..  |..| ...|   | ..
KQCWHEDPEDRPTFSEI--HECF
Kinase 88601.m00465.AA Pkinase_Tyr 18-217 29 5.6e-11 37.8 Pfam 1-209 (270) Show / Hide 
Range on Protein: 18-217
Range on HMM: 1-209/270
Sequence Identity: 29% (68 aa)

FTKVEKIGLGTYGKVYKCLDI----RKKQTVALKKIKILKPNDGFPVNT------VREIKCLKEL-KHDNIIRLRNVIT-LYKPNKPSTVWLSFDYCEF-
 |. .|.| | .|.|||.        .|..|| |..|     .|            ||.| .|.| .|.||.||  |.|   .||    ... . |..  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK-----EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN---QIYIVMEYMPHG

DLFGLLHKT--DFPQLSTKQVLCYSRQLILAMLQCKQAEILHRDLKPANLFITRDNVLKIGDFGLARKF-------KSDD-----IKYTYNVITLYYRAP
||   |.|   | ..|..|. |....|   .|    .  . ||||   |  .|..|| ||.||||||         .. .     || .         ||
DLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWM---------AP

ELILGCQNYQYEVDVWSVGCILYELCT
| |  .  .  . |||| |  ..|..|
ECINYGK-FTTKSDVWSFGVLMWEIFT
Kinase 88601.m00465.AA CDK-DD1 285-310 50 4.1e-07 17.36 In-house 354-379 (379) Show / Hide 
Range on Protein: 285-310
Range on HMM: 354-379/379
Sequence Identity: 50% (13 aa)

DLISKMCRLTPSKRISMQEAFMHPFI
|||..|  | | |||. .||  ||. 
DLIERMLTLCPKKRINTKEALQHPWF
Kinase 88601.m00465.AA MAPK 283-310 46 1e-05 15.5 In-house 301-328 (328) Show / Hide 
Range on Protein: 283-310
Range on HMM: 301-328/328
Sequence Identity: 46% (13 aa)

AADLISKMCRLTPSKRISMQEAFMHPFI
| ||..||  . |.|||. .||  ||..
AIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase 88601.m00465.AA CDK7 285-310 26 0.000418 6.35 In-house 263-288 (288) Show / Hide 
Range on Protein: 285-310
Range on HMM: 263-288/288
Sequence Identity: 26% (7 aa)

DLISKMCRLTPSKRISMQEAFMHPFI
||...|  . |.||..  ..  .|. 
DLMCGMWTMNPCKRWTCTQCLKMPYF