Gene 88914.m00122 (T.vaginalis)

88914.m00122

Species: T.vaginalis
Alias: TvagK0399, 88914.m00122
External Links:
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
88914.m00122.AA Protein None 417 None Fasta, JSON
88914.m00122.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of 88914.m00122.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 88914.m00122.AA AGC 103-354 30 5.3e-155 404.14 In-house 1-395 (395) Show / Hide 
Range on Protein: 103-354
Range on HMM: 1-395/395
Sequence Identity: 30% (122 aa)

FTILDEIGNGQYGKVKLAKKK------DTGDLYAIKTLHKQK-LVEMQ--KIHTIMCE------------RNILSKAS----------CPFIVQ-LHYAF
| .|  || | .||| |..||      |||..||.| | |..  |...  ... .| |            ||||.|..          .||||. |||.|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QSDTK--FYLCMEYVP---------GG-TLFDHMR---LSGTIPPDALKLYTAE-------LAIALHHLHV-NHIVYRD-LKPENVLLDEDGHIKLTDFG
|....   |..|||.|         ||  || |..    .|. . .. . |.||       .. ||..||  ..|..|| |||||.||||||||||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

SSKQIDESG---------------------------------------------------TLHSFCG--TPDYIAPEIVEGKPYTSKVDWWS--LGILIY
..|..  .|                                                   . ..|||  ||.|.||||.    |.  .||||  ||.|.|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMVFKAPPFYSVN----------PKRTYDKIV------NGNIIFP----------GVVDENLVSLIRGLLNKDPMRRFG----------YNEVMYHPLL
||..  ||||. |          |. ...||       | .. ||            .......||..||.||| .| |          ..|.. ||  
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 88914.m00122.AA SGK 103-354 40 5e-113 350.48 In-house 1-283 (283) Show / Hide 
Range on Protein: 103-354
Range on HMM: 1-283/283
Sequence Identity: 40% (116 aa)

FTILDEIGNGQYGKVKLAKKKDT------------------GDLYAIKTLHKQKLV-------EMQKIHTIMCER-NILSKASCPFIVQLHYAFQSDTKF
| .|  || | .||| ..|.||.                  ...||.| | ||  .          .   || || .||.. . ||||.|||||| ..| 
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YLCMEYVPGGTLFDHMRLSGTIPPDALKLYTAELAIALHHLHVNHIVYRDLKPENVLLDEDGHIKLTDFGSSK-QIDESGTLHSFCGTPDYIAPEIVEGK
|. |.|| || .| |..  .  | |  . |.||.. || .||   |.||||||||.||| .||..||||| .| .| .. |  .||||| | |||.  ..
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

PYTSKVDWWSLGILIYEMVFKAPPFYSVNPKRTYDKIVNGNIIFPGVVDENLVSLIRGLLNKDPMRRFGYN----EVMYHPLL
|.   ||||.||.. ||| . .||||| | .  ||.| |. . .|  .     .|| |||.|||  | | .    |.  ||  
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase 88914.m00122.AA Akt 103-354 43 7.6e-113 362.08 In-house 1-264 (264) Show / Hide 
Range on Protein: 103-354
Range on HMM: 1-264/264
Sequence Identity: 43% (116 aa)

FTILDEIGNGQYGKVKLAKKKDTGDLY-AIKTLHKQKLVEMQKIHTIMCERNILSKASCPFIVQLHYAFQSDTKFYLCMEYVPGGTLFDHMRLSGTIPPD
|..|. .| | .||| |.|||||...| |.| | |...... ..  .. ||||| .  .||||.|||.||. .| |..|.|..|| || |..  .... |
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

ALKLYTAELAIALHHLHVNHIVYRD-LKPENVLLDEDGHIKLTDFGSSK-Q-IDESGTLHSFCGTPDYIAPEIVEGKPYTSKVDWWS-LGILIYEMVFKA
  . | ||.  |. ||| . |.||| |||||.|.|.||||.||||| .|   | .  .  .||||| |.|||| .|. .| .||||. ||...||| . .
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

PPFYSVNPKRTYDKIVNGNIIFP--GVVDENLVSLIRGLLNKDPMRRFG--YN---EVMYHPLL
||||. . .. ..|| |... ||   ... .  .||.||||||| .| |  .|   |.. || .
PPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 88914.m00122.AA AktR 103-345 42 1.8e-102 346.72 In-house 1-254 (268) Show / Hide 
Range on Protein: 103-345
Range on HMM: 1-254/268
Sequence Identity: 42% (109 aa)

FTILDEIGNGQYGKVKLAKKK-DTGDLYAIKTLHKQKLVEMQKIHTIMCERNILS-KASCPFIVQLHYAFQSDTKFYLCMEYVPGGTLFDHMRLSGTIPP
|...  .|.| .||| |..|| |....||.| ..|.|..| ...| .  ||||.  ... ||||.|||.||...| ...|||.||| ||.| . ....  
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

DALKLYTAELAIALHHLHVN-HIVYRDLKPENVLLDEDGHIKLTDFGSSK-QID--ESGTLHSFCGTPDYIAPEIVEG-KPYTSKVDWWSLGILIYEMVF
.  . | |.  .|| .|| . .|.|||||||| |||||||.|.|||| || |..  .. . .|||||| |.|||..   |...  ||||..||.|||||.
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

KAPPFYSVNPKRTYDKIVNGN---IIFPGVVDENLVSLIR-GLLNKDPMRRFGY
  ||||. | .. ..|| . .   . .|  . ... .||  .||.|.|  | ||
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGY
Kinase 88914.m00122.AA S_TKc 103-354 34 2.6e-102 347.11 SMART 1-231 (231) Show / Hide 
Range on Protein: 103-354
Range on HMM: 1-231/231
Sequence Identity: 34% (93 aa)

FTILDEIGNGQYGKVKLAKKKDTGDLYAIKTLHKQKLVEMQKIHTIMCERNILSKASCPFIVQLHYAFQSDTKFYLCMEYVPG--GTLFDHMRLSGT---
..||..|| | .|||.....|.|| ..||| ..           .|. |..||.|  .|.||.|...||. ...|..|||..|  |.|||...  |.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---IPPDALKLYTAELAIALHHLHVNHIVYRDLKPENVLLDEDGHIKLTDFGSSKQIDESGTLHSFCGTPDYIAPEIVEGKPYTS-KVDWWSLGILIYEM
   .|.   . |..... || ..| ..|..|||||||.||||  |||..|||...|.      ..|||||.|.|||..   .|.  |.||||.|...|||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

VFKAPPFYSVNPKRTYDKIVNGNIIFPGVVDENLVSLIRGLLNKDPMRRFGYNEVMY-------HPLL
.   |||.  .......||.          .. . ..||..|.||| .| .  |..        || .
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 88914.m00122.AA PKA 103-344 44 5.70000000001e-102 345.08 In-house 1-248 (263) Show / Hide 
Range on Protein: 103-344
Range on HMM: 1-248/263
Sequence Identity: 44% (111 aa)

FTILDEIGNGQYGKVKLAKKKDTGDLYAIKTLHKQKLVEMQKIHTIMCERNILSKASCPFIV-QLHYAFQSDTKFYLCMEYVPGGTLFDHMRLSGTIPPD
| |.. .|.| .|.|.|...|..|. ||.|.| ||. | .  .. .. |.|||.  . |||| .. . || |.. |. ||||||| .|...| ||  . .
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

ALKLYTA-ELAIALHHLHVNHIVYRDLKPENVLLDEDGHIKLTDFGSSKQIDESGTLHSFCGTPDYIAPEIVEGK-PYTSKVDWWSLGILIYEMVFKAPP
  |.| | .   ||  ||  .|.|||||||| |.|..||||.|||| .| .|.  |  . ||||.|.||||. .| ..   ||||.||||||||..  ||
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD-RTW-TLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPP

FYSV--NPKRTYDKIVNGNIIFPGVVDENL---VSLIRGLLNKDPMRRFG
||    .|  .|.||.|| | ||  .| ..    .||. ||..|. .|.|
FYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYG
Kinase 88914.m00122.AA RSK 106-354 41 5.5e-95 321.87 In-house 1-278 (278) Show / Hide 
Range on Protein: 106-354
Range on HMM: 1-278/278
Sequence Identity: 41% (114 aa)

LDEIGNGQYGKVKLAKKK---DTGDLYAIKTLHKQKLVEMQK-IHTIMCERNILSKAS-CPFIVQLHYAFQSDTKFYLCMEYVPGGTLFDHMRLSGT---
| . | | |||| | .|.   ||| .|| | |.| |.|  || . . | |||||.    .||||.|||||| ..|.||.|||..|| ||.| .  ..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

IPPDALKLYTAELAIALHHLHVNHIVYRDLKPENVLLDE---DGHIKLTDFGSSKQ--IDESGTLHSFCGTPDYIAPEIVE---GKP-YTSKVDWWSLGI
.  |  . | ||.. |. |||  .|..|||||||.|.|.   .||||||||| .||  .|... ...||.| .|.|||..    ..  ..  .||||||.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LIYEMVFKAPPFYS---VNPKRTYDKIVNGN--IIFP--GVVDENLVSLIRGLLNKDPMRRFG-----YNEVMYHPLL
|.||| . .|||..    |.| . ..| .|.    .|    . ..  .|||..| .|| .| |      .|.  || .
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 88914.m00122.AA Pkinase 103-354 29 1.1e-93 322.34 Pfam 1-293 (293) Show / Hide 
Range on Protein: 103-354
Range on HMM: 1-293/293
Sequence Identity: 29% (86 aa)

FTILDEIGNGQYGKVKLAKKKDTGDLYAIKTLHKQKLVEMQKIHTIM-CERNILSKASCPFIVQLHYAFQSDTKFYLCMEYVPGG----TLFDHMR--LS
..|.  || | .|.|.....|.||...|.|.. |..  . .... .   |  |. . ..|.||.|...|..... |..|||..||     |||...   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GTI--PPDALKLYTAELAIALHHLHVNHIVYRDLKPENVLLDEDGHI----KLTDFGSSKQ--IDESGTLHSFCGTPDYIAPEIVE-GKPYTSKVDWWSL
|..  ... .| |  ... .| ..| . |..|||||||.|.|..|||    |..|||..||  .  .. ...|||||.|.|||..  |..|..|||.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GILIYEMVFKAPPFYSV------NPKRTYDKIVNGNIIFPGVVD---------------------ENLVSLIRGLLNKDPMRRFGYNEVMYHPLL
|...|||... |||..       ...  ...|  . . |.   .                     |.. ..|...|.||| .| .  ... || .
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 88914.m00122.AA RSK-Unclassified 103-344 38 1.7e-89 281.28 In-house 1-268 (283) Show / Hide 
Range on Protein: 103-344
Range on HMM: 1-268/283
Sequence Identity: 38% (103 aa)

FTILDEIGNGQYGKVKLAKKKDTGDLYAIKTLHKQKLVEMQKIHTIMCERNILSKASCPFIVQLHYAFQSDTKFYLCMEYVPGGTLFDHMR--LSGTIPP
|     || |  ||| | .||||  .||.| |||.|..  .||  .| |.||..    ||||.| ..||.  . |||||| .|| .| |.    .  .  
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE

DALKLYTAELAIALHHLHVNHIVYRDLKPENVLLDEDGHIKLTDFGSSKQI----------------------DESGTLHSFCGTPDYIAPEIVEGKPYT
|  . | .|  .|| .||   ..||||||.|..|. .||..||||. |.|                       |..    ||||| .|.|||.. .   |
DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCGHT

SKVDWWSLGILIYEMVFKAPPFYSVNPKRTYDKIVNGNIIFP--GVVDENLVSLIRGLLNKDPMRRFG
  |||| |||..||| |  ||.|  |   |.  |  ... ||    .  |  .||. ||.. | .| |
KAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLG
Kinase 88914.m00122.AA Ciliate-E2 103-354 24 1.8e-87 296.91 In-house 1-365 (365) Show / Hide 
Range on Protein: 103-354
Range on HMM: 1-365/365
Sequence Identity: 24% (91 aa)

FTILDEIGNGQYGKVKLAKK-----------------------KDTGDLYAIKTLHKQKLVEMQKIHTIM----------CERNILSKASCPFIVQLHYA
. ..  ||.|..|.|...|.                       |... .||.|...|... .. ..  ||           |.|||.. ..|.|......
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ--SDTKFYLCMEYVPGGTLFDHMR----LSGTIPP-------DALKLYTAELA---------------IALHHLHVNH-IVYRDLKPENVLLDEDGHI
||  .|...|| |||. ||.|||...     .. ...          | ......                ||..|| .. |..||.||||.|.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLTDFGSSKQIDES--------------------------------GTLHSFCGTPDYIAPEIVEGKP---------YTSKVDWWSLGILIYEMVFKAPP
|..||| ||..|..                                 . ...|||| | ||||..||.         |. |.|.||||...|||.|. ||
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FYSVNPKRTYDKIVNGNIIFP------------------GVVDENLVSLIRG----LLNKDPMRRFG-YNEVMYHPLL
|        ...| ...| ||                    ....   ||.     .|.|||  |.. ..... || .
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 88914.m00122.AA PKC 103-354 37 1.1e-86 280.98 In-house 1-262 (262) Show / Hide 
Range on Protein: 103-354
Range on HMM: 1-262/262
Sequence Identity: 37% (98 aa)

FTILDEIGNGQYGKVKLAKKKDTGDLYAIKTLHKQKLVEMQKIHTIMCERNILSKAS-CPFIVQLHYAFQSDTKFYLCMEYVPGGTLFDHMRLSGTIPPD
|. |  .| | .||| ||..|.|  .|||| | |   ..   .   |.|. .|. |. .|| ..||  ||.  . .  |||| || |  |.  ..  .  
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

ALKLYTAELAIALHHLHVNHIVYRDLKPENVLLDEDGHIKLTDFGSSK-QIDESGTLHSFCGTPDYIAPEIVEGKPYTSKVDWWSLGILIYEMVFKAPPF
  . | || ..||. || . |.||||| .|||||..||||..||| .| .. .  |  .||||||||||||.....|.  ||||..|.| |||    .||
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF

YSVNPKRTYDKIVNGNIIFPGVVDENLVSLIRGLLNKDPMRRFGY--------NEVMYHPLL
  ..     . | . |. .|    .  ||.. |...|.| .| |         .... ||. 
HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase 88914.m00122.AA Ciliate-E2-Unclassified 103-354 25 1.3e-83 284.14 In-house 1-352 (352) Show / Hide 
Range on Protein: 103-354
Range on HMM: 1-352/352
Sequence Identity: 25% (91 aa)

FTILDEIGNGQYGKVKLAKKKDTGDLYAIKTLHKQKLVEMQKIHT---------IMCERN-------------ILSKASCPFIVQLHYAFQSDTKFYLCM
..|.  ||.|..|||.....|... .||.|...|.. . ...| .         .|....             ||.   .|||| ..|.||.. ..|. |
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYVPGGTLFDHMRLSGT-----------------IPPDALK-----LYTAELAIALHHLHVNH-IVYRDLKPENVLLDEDG---HIKLTDFGSSKQIDE-
||..||.|..... ...                 ..  . |      |.|..  .| .|| .. |..||.||||.|.|..|   .||..|||.||.... 
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

---------------SGTLHSFCGTPDYI----APEIVEGKPYT----SKVDWWSLGILIYEMVFKAPPFYSVNPKR----------------TYDKIVN
               .  ...||||| |.    |||. .|. |      |.|.||||...|||.|  .|||. | .                  |..| .
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

GNIIFPG--------VVDENLVSLIR----GLLNKDPMRRFGYNEVMYHPLL
.|| ||          ....   .|.     .|.|.|  | ...... ||..
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 88914.m00122.AA Pkinase_Tyr 103-316 25 1.4e-17 60.16 Pfam 1-233 (270) Show / Hide 
Range on Protein: 103-316
Range on HMM: 1-233/270
Sequence Identity: 25% (61 aa)

FTILDEIGNGQYGKVKLAKKK----DTGDLYAIKTLHKQKLVEMQ-KIHTIMCERNILSKA-SCPFIVQLHYAFQ-SDTK--FYLCMEYVPGGTLFDHMR
 |.. ..| |..|.|.... |    .|.   |.|.| |..  . | ..   | | .|...  ..| ||.|. .    .     |. |||.|.| | |. |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

L----SGTIPPDALKLYTAELAIALHHLHVNHIVYRDLKPENVLLDEDGHIKLTDFGSSKQI--------DESGTLHSFCGTPDYIAPE-IVEGKPYTSK
      . ...  |  . .. | .. .|. .... |||   |.|..|....| .||| .. |          .|.      .    ||| | .|| .|.|
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWM----APECINYGK-FTTK

VDWWSLGILIYEMVFKA-PP-FYSVNPKRTYDKI-VNGN
 | || |.|..|..     | .. . . . |..|  .|.
SDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGY
Kinase 88914.m00122.AA TyrKc 103-354 20 9.8e-16 31.75 SMART 1-280 (280) Show / Hide 
Range on Protein: 103-354
Range on HMM: 1-280/280
Sequence Identity: 20% (59 aa)

FTILDEIGNGQYGKVKLAKKKDTGDLYAIKTLHKQKLVEMQKIHTIMCERNILSKA--SCPFIVQLHYAFQSD-------TKFYLCMEYVPGGTLFDHMR
 | ....|.|..|.| ... |      |.|.|.. .      .  .| | .|..|   . | ||.|. .  ..          .. |||.|.| | |. |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

LSGT-IPPDALKLYTAELAIALHHLHVNHIVYRDLKPENVLLDEDGHIKLTDFGSSKQIDES-------GTLHSFC--GTPD-----YIAPEIVEGKPYT
 ..  .... |  .    |    .|| .... |||   |.|..|....| .||| |. |..         . ..    |. .       |||    . .|
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

SKVDWWSLGILIYEMV-FKAPPFYS-----VNPKRTYDKIVNGNIIFPGVV---------DENLVSLIRGLLNKDPMRRFGYNEVMYHPLL
.| | || |....|.  . ..| .      ..... . .. .|.   .             . . ....   . ||  |   .|.  | ..
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF