Gene 82360.m00219 (T.vaginalis)

82360.m00219

Species: T.vaginalis
Alias: 82360.m00219, TvagK0273
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
82360.m00219.AA Protein None 1000 None Fasta, JSON
82360.m00219.kin_dom Protein Kinase Domain None 251 None Fasta, JSON

Protein domain

Protein domains of 82360.m00219.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 82360.m00219.AA TKL 24-268 21 1.2e-60 207.76 In-house 1-364 (364) Show / Hide 
Range on Protein: 24-268
Range on HMM: 1-364/364
Sequence Identity: 21% (80 aa)

IGRGGAAEVFKSYDSKLK--------VECAVKRLYKEDLSDKSL-------------------------AHLIREIHTMALINNRFCMPMLGFSAVPP--
||.|| .||.| .              . |||.. ... . ...                          ....||  |  ..     ...|..  ||  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------YCLVLEYLQNGS-LDEAIFRANRKQMSETHMCIIALCIANGMAHIHAHG--------VYHRDLKPGNVLLDEKEI-------------
            .|.| || ..|| |.  .           ..| .|| || ||.. |...        . |||||. |.|.||.               
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW

-PRICDFGLARIENGTKCSK---------------------GIGTPNYMAPEQIEST----------------QYTHKVDVYAYGVMLYEMVERQRAFTG
 . ||||||.|  .... ..                      .|||..|||| .. .                .|. |.|||..|..|.|.. |.| . .
CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYD

YTVKSEL---------INAITRGERPQFT---------RKTHKT---MQHLITRCWDQDPNNRPEFTEIFDQI
|   ...         . .. .|.||             . . .   |  |...|||.||..|| |.|| ...
YPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Pkinase 82360.m00219.AA Pkinase 18-268 23 3e-58 204.65 Pfam 1-293 (293) Show / Hide 
Range on Protein: 18-268
Range on HMM: 1-293/293
Sequence Identity: 23% (71 aa)

FSEISMIGRGGAAEVFKSYDSKLKVECAVKRLYKEDLSDKSLAHLIR--EIHTMALINNRFCMPMLGFSAVPPYCL-VLEYLQNG----SLDEAIFRANR
.  .. ||.|. ..|.| .. .   . |||.. |.. ... . ...|  ||. |. .|  .   ....   ....  |.||...|    .| . | . ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KQM--SETHMCIIALCIANGMAHIHAHGVYHRDLKPGNVLLDEKEIP----RICDFGLAR---IENGTKCSKGIGTPNYMAPEQIE-STQYTHKVDVYAY
. .  || . . ... |. |....|..|. |||||| |.|.|..  .    .|||||||.   . |.. ..   |||.||||| |  .. |..|||....
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVMLYEMVERQRAFTGYTVKSEL----------INAITRGERPQFTRKTH---------------------KTMQHLITRCWDQDPNNRPEFTEIFDQ--
|..||||.       |..  ..           . . ..| .. | . .                      ......|..|...||. || ...|.    
GCILYEMLC------GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPW

I
.
F
S_TKc 82360.m00219.AA S_TKc 18-269 25 5.7e-58 199.81 SMART 1-231 (231) Show / Hide 
Range on Protein: 18-269
Range on HMM: 1-231/231
Sequence Identity: 25% (69 aa)

FSEISMIGRGGAAEVFKSYDSKLKVECAVKRLYKEDLSDKSLAHLIREIHTMALINNRFCMPMLGFSAVPPYCLVLEYLQN--GSLDEAIFRANR----K
.  .  ||.|. ..|.| .. | . ..|.|..           |..|||  .   .  .   ....     ...|.||. .  |.| . | . .|    .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

QMSETHMCIIALCIANGMAHIHAHGVYHRDLKPGNVLLDEKEIPRICDFGLARIENGTKCSKGIGTPNYMAPEQIESTQYTH-KVDVYAYGVMLYEMVER
...| | . ..  |.......| ||. |||||| |.||||     ||||||||.      .  .|||.||||| .   .|.. |.|... |..||||. .
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCG

QRAFTGYTVKSELINAITRGERPQFTRKTHKTMQHLITRCWDQDPNNRPEFTEIFD--------QIA
.  |       .... |             . . ..| .|.. ||..||   |..         .  
YPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 82360.m00219.AA TKL-Unique 21-268 26 3.4e-53 183.05 In-house 2-290 (290) Show / Hide 
Range on Protein: 21-268
Range on HMM: 2-290/290
Sequence Identity: 26% (78 aa)

ISMIGRGGAAEVFKSYDSKLKVECAVKRLYK-EDLSDKSLAHLIREIHTMALIN-NRFCMPMLGFSA----VPP-YCLVLEYLQNGSLDEAIFR------
.. ||.||...|.|    . .|  |.|.. . ||.| ...  ...|. .|  ..   .     |...     || .|.|.||.. |||.. . .      
WNKIGEGGYGQVYKGKWRGYPV--AIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

--ANRKQMSETHMCIIALCIANGMAHIHAHG--VYHRDLKPGNVLLDEK------EIPRICDFGLARIEN-GTKCSKG----------IGTPNYMAPEQI
  .| . ..   .  .|..|| || ..|  .  ..|||||. |.|.|..       | .||||||... .  .| ...          .|....|||| .
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNI-KICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

ES--TQYTHKVDVYAYGVMLYEMVERQR------AFTGYTVK--SELINAITRGERPQFTRKTHKTMQHLITRCWDQDPNNRPEFTEIFDQI
..  .||. |.|||..|..|.|...|..       . |.. .   |..    .. ||       |  ..||..||..|| .|| |.||   .
RMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase 82360.m00219.AA AGC 18-259 17 3.7e-47 118.81 In-house 1-374 (395) Show / Hide 
Range on Protein: 18-259
Range on HMM: 1-374/395
Sequence Identity: 17% (65 aa)

FSEISMIGRGGAAEVFKSYDS------KLKVECAVKRLYKED---LSDK-SLAHLIRE------------IHTMALIN----------NRFCMP-MLGFS
|  . .||.|.  .|.   .         .  .|.| | |..   . .|  ..| ..|             . ....|          . |    .    
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

AVPPY---CLVLEYLQ---------NG-SLDEAIFRA-NRKQMSETHMCIIALC-------IANGMAHIHA-HGVYHRD-LKPGNVLLDEKEIPRICDFG
  . .   ..|.||..          |  |   ..   ... ..| . ...| .       |. .. ..|  .|. ||| ||| |.||||.   ...|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LARI----------------------------------------------------ENGTKCSKGIG--TPNYMAPEQIESTQYTHKVDVYA--YGVMLY
|. .                                                    ... ...   |  ||.||||| .    |.. .| ..  .|...|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMVERQRAFTGYTV---------KSELINAITRG-----ERPQFT----------RKTHKTMQHLITRCWDQDPNNRP
||.  .  |.| ..         . |. . |  |     ....|           |.  .  ..||...   ||..|.
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRL
Kinase 82360.m00219.AA MLK 87-268 30 1.8e-43 148.71 In-house 82-291 (291) Show / Hide 
Range on Protein: 87-268
Range on HMM: 82-291/291
Sequence Identity: 30% (64 aa)

PP-YCLVLEYLQNGSLDEAIFRANRKQM------------SETHMCIIALCIANGMAHIHAHG---VYHRDLKPGNVLLDE------KEIPRICDFGLAR
|. .|.|.||...||| . .  |. | |            .  |.  .|| .|.||.  |..    . |||||. |.|.||      ... .|||||..|
PCHFCIVMEYCEGGSLYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSR

-IENGTK-CSKGIGTPNYMAPEQI---ESTQYTHKVDVYAYGVMLYEMVERQRAFT-GYTVKSELINAITRGERPQFTRKTHKTMQHLITRCWDQDPNNR
 . . ..   . .||. .|||| |   ....|. |.||. .||.|.||. |.  .  .|     .. ..  |.||       . .  |...||.|||..|
DWHQMCTNMMSNAGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKR

PEFTEIFDQI
| | .|  . 
PSFRQIVQHL
Kinase 82360.m00219.AA LRRK 88-270 28 2.7e-43 150.13 In-house 129-351 (351) Show / Hide 
Range on Protein: 88-270
Range on HMM: 129-351/351
Sequence Identity: 28% (63 aa)

PYCLVLEYLQNGSLDEAIFRANRKQ-------MSETHMCIIALCIANGMAHIHAHG--VYHRDLKPGNVLL---D---------EKEIPRICDFGLAR--
|.|.|.||...|.|.. ..   . .       .| .    ||| || ||.. | |   . |||||. |.||   .         .  .  |.|||. |  
PLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMF

IENGTK-CSKGIGTPNYMAPEQIEST---QYTHKVDVYAYGVMLYEMVERQ-RAFTGYT-V-----KSELINAITRGERPQFTRK-THK-----TMQHLI
   ...  ..  |.| .|||| .  .   .|| |||.|..|. |.| . || ..| ... .      ... ..|..| || .     .       .| ||
QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIEDKIIEGLRPTIPQHYCPPCQPWHMYQDLI

TRCWDQDPNNRPEFTEIFDQIAD
. ||..||..|| |..|.... .
QHCWQHDPKKRPHFSQIVKRLSQ
Kinase 82360.m00219.AA STE 18-263 17 6.6e-43 148.87 In-house 1-350 (359) Show / Hide 
Range on Protein: 18-263
Range on HMM: 1-350/359
Sequence Identity: 17% (64 aa)

FSEISMIGRGGAAEVFKSYDSK---------------LKVECAVKRLYKEDLS---------------DKSLAHLIREIHTMALIN--NRFCMPMLGFSA
.  |..||.|.  .|.| .. |                .. .|.|.. .|. .               .. .  ...|| .|   |    .    .|   
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

VPP--------YCLVLEYLQNGSLDEAIFRANRKQMS------------ETHMCIIALCIANG-MAHIHAHGVYHRDLKPGNVLLDEKEIPRICDFGLAR
.           ....||. .||||. | .   ....            |.  ..|.  |  | ....| |.. |||.||.|.||       .||||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

-IEN-----------------GTKCSKGIGTPNYMAPEQIES------TQYTHKVDVYAYGVMLYEMVERQRAFTGYTVKSELINAITR-----------
 ...                 . |.   .||| .|||| |.        .|. |.|..  | .. ||.. .  .  ..  . . ....            
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---GERPQFTRKTH-------------------KTMQHLITRCWDQDPNNRPEFTE
   |. |..  ...                   . ... | .| . |||.||  ..
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQ
Kinase 82360.m00219.AA TyrKc 18-268 23 2e-40 141.55 SMART 1-280 (280) Show / Hide 
Range on Protein: 18-268
Range on HMM: 1-280/280
Sequence Identity: 23% (67 aa)

FSEISMIGRGGAAEVFKSYDSKLKVECAVKRLYKEDLSDKSLAHLIREIHTMALI--NNRFCMPMLGFSAV--------PPYCLVLEYLQNGSLDEAIFR
 . . ..|.|   ||.|   .   ...||| | ..      .. ..||.  |  .  ..     ..|            .|...|.||  .|.|.. . |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL-R

ANRKQMSETHMCIIALCIANGMAHIHAHGVYHRDLKPGNVLLDEKEIPRICDFGLARIENGT---------KCSKG-IGTP-----NYMAPEQIESTQYT
..|.. .  ... ... ||.||...| ... ||||   |.|..|. . .|.||||.|              . .|.  |.        |||| |    .|
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

HKVDVYAYGVMLYEMVERQRAFTGY-----TVKSELINAITRGERPQFTRK--------THKTMQHLITRCWDQDPNNRPEFTEIFDQI
.| ||...||...|.  .               .|.|. . .|.|.              .. |  ....||. ||..|| |.|| ...
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 82360.m00219.AA Dicty5 94-269 33 4.9e-38 128.51 In-house 79-260 (260) Show / Hide 
Range on Protein: 94-269
Range on HMM: 79-260/260
Sequence Identity: 33% (61 aa)

EYLQNGSLDEAIFRANRK----QMSETHMCIIALCIANGMAHIHAHGVYHRDLKPGNVLLDEKEIPRICDFGLAR-IENGTKCSKGIGTPNYMAPEQIES
|| .|||| ..  .  ||     ..      .|. ||..| |.|  .. |||||  |.|. |     | |||  | ..|  .    .||...||.|   .
EYCHNGSLFNYL-NDQRKTTGQPIAYFQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFNG

TQYTHKVDVYAYGVMLYEMVERQRAFTGYTVKSELINAITRGERPQFTRKTHKTMQHLITRCWDQDPNNRPEFTEI---FDQIA
  |. |.|||..|. |.||  |  ..   . . .  . .  ||||        .   ||  || | | ||| |.||   |..| 
QPYHQKCDVYSFGIVLWEMFTRKEPYDNIN-NWNIPVMVMKGERPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII
Kinase 82360.m00219.AA CAMK 23-208 17 9.3e-38 118.74 In-house 1-328 (425) Show / Hide 
Range on Protein: 23-208
Range on HMM: 1-328/425
Sequence Identity: 17% (56 aa)

MIGRGGAAEVFKSYDSKLK------------VECAVKRLYKEDLS--------------------------DKSLAHLIREIHTMAL-------INNRFC
 .|||. ..|.. .. . .            ...|.| . |. |.                          .|... . |||. | .       .. .  
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

MPMLGFSA------------VPP---------YCLVL---EYLQNG----SLDEAIFRANR-------------KQMSETHMCIIALCIANGMAHIHAHG
  .. .                          ...|.   || ..|     | . | .  .             . ..|   . .   |. .....| |.
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

VYHRDLKPGNVLLDEKE-----------------IPRICDFGLARIEN-------------------------GTKCSKGIGTPNYMA-PEQIES-----
. |||||| |.|||...                    |.|||.|.. .                         | |..   ||| ||| || ...     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------TQYTHKVDVYAYGVMLYEMV
         . |. |.|. . ||.|| |.
MQNATDEEKPYYGPKCDMWSCGVILYIML
Kinase 82360.m00219.AA Pkinase_Tyr 41-268 26 3.4e-35 119.8 Pfam 28-270 (270) Show / Hide 
Range on Protein: 41-268
Range on HMM: 28-270/270
Sequence Identity: 26% (66 aa)

KVECAVKRLYKEDLSDKS--LAHLIREIHTMALI-NNRFCMPMLGFSA-V-PP--YCLVLEYLQNGSLDEAIFRA--NRKQMSETHMCIIALCIANGMAH
|...||| | ||. ...   .. ..||. .|  . ..     ..|       |  ...|.|| ..|.|..   .   .... .  ... ... ||.||..
KIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEY

IHAHGVYHRDLKPGNVLLDEKEIPRICDFGLARIE----NG-TKCSKGIGTPNYMAPEQIESTQYTHKVDVYAYGVMLYEMVE-RQRA-FTGYTVKSELI
 ....  ||||   |.|..|. . .||||||||      .  .| ..|      |||| |    .|.| ||...|| ..|..   .   . |    .|..
LESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGM-SNEEVY

NAI-TRGERPQFTRKTHKTMQHLITRCWDQDPNNRPEFTEIFDQI
..|  .|.|    ..... . .|...||..||..|| |.||  |.
EYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase 82360.m00219.AA TKL-ciliate1 91-268 25 2e-34 115.23 In-house 76-279 (279) Show / Hide 
Range on Protein: 91-268
Range on HMM: 76-279/279
Sequence Identity: 25% (52 aa)

LVLEYLQNGSLDEAIFRANR--KQMSETHMCIIALCIANGMAHIHAHG--VYHRDLKPGNVLLDEKEIPRICDF--------GLARIENGTKC---SKGI
.. |.   |....   |     ..... |   .   || || ..|       |||||  | |.||   . ||.|        ...| ..       ..  
IIMEHCHKGTMFDICHRKHSQIYMIKWQHRMRWCKDIAQGMQYLHMRQNPLIHRDLKMQNILYDEPYQYKICNFPHVKIADFHRIRNCSFQDMQNEMQRN

GTPNYMAPEQIE-----STQYTHKVDVYAYGVMLYEMVERQRAF-TGYTVKSELINAITRGE-RPQF-----TRKTHKTMQHLITRCWDQDPNNRPEFTE
.|. .|||||.        ... |.|.||||. .|... |   |     | ..  . .  .  ||         ..   .  |. |||.|.|| ||.| |
TTFHWMAPEQMDPHIFPNYPINEKIDIYAYGIVMYILCFRKTPFQQKMSVINIMCY-WCEFPGRPNLGPQFIHFDCPQNFHNLMMRCWCQNPNKRPNFNE

IFDQI
| . .
IIQIL
Kinase 82360.m00219.AA Ciliate-E2 18-266 17 2.5e-34 115.25 In-house 1-361 (365) Show / Hide 
Range on Protein: 18-266
Range on HMM: 1-361/365
Sequence Identity: 17% (64 aa)

FSEISMIGRGGAAEVFKSYDSKLKV------------------ECAVKRLYKEDLSDKSLAHLIREIHTM----------------ALINNRFCMPMLGF
.  | .||.|. . |.|  . | .                   ....|  ... .. . . .. .||| |                 ..|. . . |  .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

SA---VPPYCLVLEYLQNGSLDE-----AIFRANR----KQMSETHMCIIALCIAN---------------GMAHIHAHG-VYHRDLKPGNVLLDEKEIP
        . ||.||.| |.| .      ..| .     |...| ... |   |..               .. ..|  . . |||.|| |.|.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

RICDFGLARIEN------------GTKCSKG----------------------IGTPNYMAPEQIESTQ---------YTHKVDVYAYGVMLYEMVERQR
 |.||||... .            . .   .                      .|||.||||| ... .         |..|.|... ||.||||.  ..
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

AFTGYTVKSELINAITRGERPQFTRKTHKTMQ---------------HLITR----CWDQDPNNRPE-FTEIFD
 |       . ..   .   |... . .. .                .|| .    . . ||..|.  . .|..
PF-----QQQIKQCKIDFPCPEWQKD-TQ-CIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN
Kinase 82360.m00219.AA LRRK 18-34 33 0.004763 6.61 In-house 1-18 (351) Show / Hide 
Range on Protein: 18-34
Range on HMM: 1-18/351
Sequence Identity: 33% (6 aa)

FSEISMIGRGGAA-EVFK
. . ..||||| . .|..
LKIEEQIGRGGFGTFVYR