Gene 84263.m00173 (T.vaginalis)

84263.m00173

Species: T.vaginalis
Alias: TvagK0377, 84263.m00173
External Links:
Annotation:

Classification

Group: AGC
Family: NDR
Subfamily: NDR-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
84263.m00173.AA Protein None 456 None Fasta, JSON
84263.m00173.kin_dom Protein Kinase Domain None 284 None Fasta, JSON

Protein domain

Protein domains of 84263.m00173.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 84263.m00173.AA AGC 100-383 27 3.2e-141 367.66 In-house 1-395 (395) Show / Hide 
Range on Protein: 100-383
Range on HMM: 1-395/395
Sequence Identity: 27% (110 aa)

FNYIKLIGRGGFADVWLVTDK-------NAQIYALKIIRKAD-VILND--QVQSVINE------------RNILSVAN----------NNWIVN-LHSSF
|. .|.||.|.|  |.|| .|       . ..||.|...|.. .....  .|. ...|            ||||. .|          . .||. ||.||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDNDH--LYLLLDFVQ---------GG-DLMNALV---KINTFPYPVARFFAGE-------IVLALHYIHQ-LGYVHSD-VKPDNILINSDGHIKLTDFG
||.||  ||.......         || .|.  |    |  .|. ..|||.| |       |||||.|.|. .|..| | .||.|||...||||||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

IAS----------------SYNKVDNDYNNLLINSQDLLIDSSSIVSTANNRHHR-------------QRSSIVG--TIDYVAPEVILGEAPSVESDWWS
 .                 ....  |  .. .. . |   . ..    .| ....             . ....|  | .|.|||..     . . ||||
LCKEGMNDGEKGQQSQSNMKFHW-HNKKYQ-KS-NMD---T-NK-CNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWS

--FGVILYEFLYGFTPFASES----------KQETALRIV------HWRKSL------RIPASQRVPTVALDLIRKLLC-DKEQRIG----------FDE
  .|...||.|.| .|| ...          . |.  .|       .|.  .       .|. . .   | |||.|||| | |.|.|          ..|
FGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEE

IIAHPFF
| .||.|
IKNHPWF
Kinase 84263.m00173.AA NDR 100-383 35 1.2e-112 348.86 In-house 1-350 (350) Show / Hide 
Range on Protein: 100-383
Range on HMM: 1-350/350
Sequence Identity: 35% (124 aa)

FNYIKLIGRGGFADVWLVTDK-NAQIYALKIIRKADVILNDQVQSVINERNILSVAN--NNWIVNLHSSFQDNDHLYLLLDFVQGGDLMN---ALVKINT
|  ||.||.|.|  ||||  | . .|||.||.||....  .|| .| .|| |...|.  |.|.| |  |||| ..|||  ... |||.|     |.| ..
FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI

FPYPVARFFAGEIVLALHYIHQLGYVHSDVKPDNILINSDGHIKLTDFGIASS---------------------------------YNKVDNDYNNLLIN
|.  .|||   |.|.|....|..||.| |.||||.||..|||||||||| .                                   .... .. ..  .|
FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLCTGGMIRRHWKQNKQKKPMTTYSTFHWTHNSWYYQNMKEHRPQDFMDNWN

SQDLLIDSSSI----------VSTANNRHHRQRS-----SIVGTIDYVAPEVILGEA-PSVESDWWSFGVILYEFLYGFTPFASESKQETALRIVHWRKS
|..    ....          | . |||  .|.      |.||| || ||||....   . . |||| |.|.||.| |..|| |.. |||  .| .|.. 
SNPMNQKCKCHTQMKDQMKCNVKVLNNRSWKQNRRCLAYSTVGTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQT

L-----RIPASQRVPTVALDLIRKLLC-DKEQRIG-----FDEIIAHPFF
.      .|. . .   | ||||.|.| |...|.|     .||| .||||
WDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHGKGVDEIKSHPFF
Kinase 84263.m00173.AA MAST 100-383 31 9.2e-93 299.36 In-house 1-334 (334) Show / Hide 
Range on Protein: 100-383
Range on HMM: 1-334/334
Sequence Identity: 31% (108 aa)

FNYIKLIGRGGFADVWLVTDKNA-QIYALKIIRKADVILNDQVQSVINERNILSVANNNWIVNLHSSFQDNDHLYLLLDFVQGGDLMNALVKINTFPYPV
|. ||.|..|..  |.||  |.  ...|.|.|.|.| |.  .|..|. |||||... |...|.. .|||  ..|.. .....|||.   |  ...|. . 
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

ARFFAGEIVLALHYIHQLGYVHSDVKPDNILINSDGHIKLTDFGIASSYNKV--DNDYNNLLIN--SQDLLIDSSSIVSTANNRHHR-------------
|..   |.||.| |.|. | || |.||||.|| |.||||||||| .    ||   .| |.. ..  . ...  | .  .. ..   .             
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLS----KVGFMDDLNMMYEGYTPPNIFNNSTDPMNKNQQDYSQFPGDFGINGNTNK

-----------------------QRSSIVGTIDYVAPEVILGEA-PSVESDWWSFGVILYEFLYGFTPFASESKQETALRIVHWRKS-LRIPAS------
                       |  ...|| || |||||||.   .  .|||| |.|.|||| | .||  .. .|.   |.. .     .|        
NQIQQQQEQPQCQQQNMRPHNIHQNKQCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDD

QRVPTVALDLIRKLL-CDKEQRIGFD----EIIAHPFF
   . .| |||.||| .| ..|.|.     |.  ||||
EAMSPEAQDLIEKLLQPDPRKRLGANNGADEVKQHPFF
Kinase 84263.m00173.AA S_TKc 100-383 28 2.9e-87 297.11 SMART 1-231 (231) Show / Hide 
Range on Protein: 100-383
Range on HMM: 1-231/231
Sequence Identity: 28% (87 aa)

FNYIKLIGRGGFADVWLVTDKN-AQIYALKIIRKADVILNDQVQSVINERNILSVANNNWIVNLHSSFQDNDHLYLLLDFVQG--GDLMNALVKINT---
.  ...||.|.|. |.....|.  .|.|.|||.          .....|..||.  .  .||.|. .||| ||||. .... |  |||.  ..| ..   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FPYPVARFFAGEIVLALHYIHQLGYVHSDVKPDNILINSDGHIKLTDFGIASSYNKVDNDYNNLLINSQDLLIDSSSIVSTANNRHHRQRSSIVGTI
   ||  .|||.. .|..|| |.|..| .| |.||.|||...  |||..|||.|  .                                    ....|| 
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------------------------------------TTFCGTP

DYVAPEVILGEAPSV-ESDWWSFGVILYEFLYGFTPFASESKQETALRIVHWRKSLRIPASQRVPTVALDLIRKLLC-DKEQRIGFDEIIA-------HP
.|.||||.     .  ..||||.|.||||.|.| .||     ... ....              .  |.|.|||.|. | |.|..  |. .       ||
WYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHP

FF
.|
WF
Kinase 84263.m00173.AA DMPK 100-242 42 4.4e-78 192.25 In-house 1-145 (270) Show / Hide 
Range on Protein: 100-242
Range on HMM: 1-145/270
Sequence Identity: 42% (61 aa)

FNYIKLIGRGGFADVWLVTDKNA-QIYALKIIRKADVILNDQVQSVINERNILSVANNNWIVNLHSSFQDNDHLYLLLDFVQGGDLMNALVKIN-TFPYP
|  .|.|||| |. | .|  |.. ..|| |.. |.. .   ..  .  ||.|.. .|  ||..||  |||...||.  ..  |||| . . .    .|  
FEILKVIGRGHFGEVQVVRHKQTNDVYAMKMMNKWEMLKRAETACFWEERDIMVHGNSRWITQLHYAFQDENYLYMVMEYMPGGDLLTLMSRYEDRIPED

VARFFAGEIVLALHYIHQLGYVHSDVKPDNILINSDGHIKLTDFG
 |||   |.|||.| |||.|||| |.||||.|. . ||||| |||
MARFYLAEMVLAIHSIHQMGYVHRDIKPDNMLLDRHGHIKLADFG
Kinase 84263.m00173.AA RSK 103-383 32 1.4e-74 254.1 In-house 1-278 (278) Show / Hide 
Range on Protein: 103-383
Range on HMM: 1-278/278
Sequence Identity: 32% (100 aa)

IKLIGRGGFADVWLVTDK----NAQIYALKIIRKADVILNDQ-VQSVINERNILSVAN-NNWIVNLHSSFQDNDHLYLLLDFVQGGDLMNALVKINT---
.|. |.||.  | |.  .    . |||| |...|| .. ..  .  .  |||||.  .    ||.|| .||....||| .... ||.|   | |  .   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FPYPVARFFAGEIVLALHYIHQLGYVHSDVKPDNILINS---DGHIKLTDFGIASSYNKVDNDYNNLLINSQDLLIDSSSIVSTANNRHHRQRSSIVGTI
|    |.| . |||||. ..||.| .| | ||.||| ..   .||||||||| .                               ...|  .  . ..||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF----------------------------RCDHNQWTMTFCYTI

DYVAPEVIL----GEAPSVESDWWSFGVILYEFLYGFTPFAS---ESKQETALRIVHWRKSLRIPASQRVPTVALDLIRKLLC-DKEQRIG-----FDEI
.|.|||..     ... .   ||||.||..|| | |..||..   ....|.  || . . ||..|. | . . | |||||.|. | ..|.|      .||
EYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEI

IAHPFF
 .||.|
KQHPWF
Kinase 84263.m00173.AA Ciliate-E2 100-383 21 8.5e-74 251.48 In-house 1-365 (365) Show / Hide 
Range on Protein: 100-383
Range on HMM: 1-365/365
Sequence Identity: 21% (86 aa)

FNYIKLIGRGGFADVWLVTDKNA------------------------QIYALKIIRKADVILNDQVQSVI----------NERNILSVANNNWIVNLHSS
.. ||.||.|.|..|.......                         .|||.||..| ...   |.....          ||.|||.  |.. |.... .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ--DNDHLYLLLDFVQGGDLMN-------------------ALVKINTFPYPVAR-------FFAGEIVLALHYIHQLG-YVHSDVKPDNILINSDGHI
||  |....|| ....|||||.                     . .| .. . ...       |....|.|||.|.|. .  .| | ||.|||.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLTDFGIASSYNKVDNDYNNLLINSQDLLIDS------SSIVSTANNRHHRQRSSI----------VGTIDYVAPEVILGEA---------PSVESDWWS
|..|||..  |..  ...   .  .. ..  .      ... .            .          .||  |.|||.. |.           . ..|.||
KIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMD------------QIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWS

FGVILYEFLYGFTPFASESKQETALRIVHWRK-SLRIP----------------ASQRVPTVALDLIRK-----LLCDKEQRIG-FDEIIAHPFF
.||||||.|.| .||           .    .  ...|                  . ..  . |||.|     | .| |.||. ...|. ||.|
LGVILYEMLFGKPPF-----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 84263.m00173.AA AktR 100-383 31 6e-73 248.67 In-house 1-268 (268) Show / Hide 
Range on Protein: 100-383
Range on HMM: 1-268/268
Sequence Identity: 31% (94 aa)

FNYIKLIGRGGFADVWLVTDK--NAQIYALKIIRKADVILNDQVQSVINERNILS-VANNNWIVNLHSSFQDNDHLYLLLDFVQGGDLMNALVKINTFPY
| ..|..|.|.|..| ||..|  | ..||.|.|.| . | . | . .|.||||.   .|.. ||.|| .||....|........||.| . | |...|  
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

PVARFFAGEIVLALHYIHQL-GYVHSDVKPDNILINSDGHIKLTDFGIASSYNKVDNDYNNLLINSQDLLIDSSSIVSTANNRHHRQRSSIVGTIDYVAP
 .|||.. .|.||| | ||    .  | ||.|||. .|||.|.|||| .                               . .  ... |..||  |.||
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK--------------------------LQFMMHYDEKAY-SFCGTPEYMAP

EVILG-EAPSVESDWWSFGVILYEFLYGFTPFASESKQETALRIVHWRKSLRIPASQRVPTVALDLIR-KLLCDKEQ-RIG-----FDEIIAHPFF
|.|.  .     .|||.||. .|| ..| .|| ......  ..|   .  ...| .  .   . |||  ||||.  . |.|     ..||  ||.|
EMITKKKGHNKSVDWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQ-QNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 84263.m00173.AA Pkinase 100-383 25 3.9e-68 237.46 Pfam 1-293 (293) Show / Hide 
Range on Protein: 100-383
Range on HMM: 1-293/293
Sequence Identity: 25% (84 aa)

FNYIKLIGRGGFADVWLVTDKNAQI-YALKIIRKADVILNDQVQSVIN--ERNILSVANNNWIVNLHSSFQDNDHLYLLLDFVQGG----DLMNALV--K
.  .. ||.|.|. |.. ..|. .. .|.|||.|   .  .. |. ..  |  |.   |   || |. .|.|.||.|. .....||    ||.  .   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

INTF--PYPVARFFAGEIVLALHYIHQLGYVHSDVKPDNILINSDGHI----KLTDFGIASSYNKVDNDYNNLLINSQDLLIDSSSIVSTANNRHHRQRS
 ..|  .. ...|.. .|. .| |.|. | .| |.||.||||...|||    |..|||.|  ..                            . . .  .
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----------------------------Y-NNS-MT

SIVGTIDYVAPEVIL-GEAPSVESDWWSFGVILYEFLYGFTPFASE------SKQETALRIVHWRKSLRIPASQRVP-----------------TVALDL
...||..|.|||||. |.  . ..|.||.|.||||.| | .|| ..      ....   || . . .  .| . ...                   ..|.
TFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDF

IRKLLC-DKEQRIGFDEIIAHPFF
|...|| | ..|.....|  ||.|
IKWCLCKDPKKRPTAEQILQHPWF
Kinase 84263.m00173.AA MAST 100-242 40 1.8e-65 198.71 In-house 1-147 (337) Show / Hide 
Range on Protein: 100-242
Range on HMM: 1-147/337
Sequence Identity: 40% (60 aa)

FNYIKLIGRGGFADVWLVTDK-NAQIYALKIIRKADVILNDQVQSVINERNILSVANNNWIVNLHSSFQD--NDHLYLLLDFVQGGDLMNALVKIN-TFP
|. ||.|..|..  |.||  |   ...|.|.|.. | |.  ||..|. |||||... |...|.. .|||    ..|.. .....|||    |  .. ..|
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

YPVARFFAGEIVLALHYIHQLGYVHSDVKPDNILINSDGHIKLTDFG
   |..   |.||.| |.|  | || |.||||.|| |.|||||||||
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFG
Kinase 84263.m00173.AA CRIK 100-244 43 5.5e-49 154.12 In-house 1-147 (272) Show / Hide 
Range on Protein: 100-244
Range on HMM: 1-147/272
Sequence Identity: 43% (64 aa)

FNYIKLIGRGGFADVWLVTDKNAQ-IYALKIIRKADVILNDQVQSVINERNILSVANNNWIVNLHSSFQDNDHLYLLLDFVQGGDLMNALVKIN-TFPYP
|    |||.| |..| .|  |    ||| |...|. |   .||  .  ||.|.| .|  |. .|   |||||.|||   .  ||||   .      |   
FEVKDLIGCGHFGQVQVVREKQTNDIYAMKVMHKKVVLAQEQVSFFEEERDIMSRRNSPWLPQLQYAFQDNDNLYLMMEYHPGGDLLSLMNRHDDQFDEN

VARFFAGEIVLALHYIHQLGYVHSDVKPDNILINSDGHIKLTDFGIA
 |||.  | ..|.| .|. |||| |.||.||||   ||||| ||| |
MARFYLAELIVAVHSLHEMGYVHRDIKPENILIDRTGHIKLADFGSA
Kinase 84263.m00173.AA GEK 100-242 44 1.7e-48 160.68 In-house 1-145 (269) Show / Hide 
Range on Protein: 100-242
Range on HMM: 1-145/269
Sequence Identity: 44% (64 aa)

FNYIKLIGRGGFADVWLVTDKNA-QIYALKIIRKADVILNDQVQSVINERNILSVANNNWIVNLHSSFQDNDHLYLLLDFVQGGDLMNALVKI-NTFPYP
|. .|.|||| |..|  |  ||. |.||.||. | ...    .     || .|    . || |||  |||...||| .|.  ||||.  | |  .  |  
FEILKVIGRGAFGEVAVVKMKNTDQVYAMKILNKWEMLKRAETACFREERDVLVNGDRRWITNLHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDRLPED

VARFFAGEIVLALHYIHQLGYVHSDVKPDNILINSDGHIKLTDFG
.|||. .|.|.|.. .|||.||| |.||||.|.   |||.| |||
MARFYIAEMVMAIDSVHQLHYVHRDIKPDNVLLDMNGHIRLADFG
Kinase 84263.m00173.AA DMPK 287-383 41 4.9e-47 113.73 In-house 162-270 (270) Show / Hide 
Range on Protein: 287-383
Range on HMM: 162-270/270
Sequence Identity: 41% (45 aa)

VGTIDYVAPEVILGEAPS------VESDWWSFGVILYEFLYGFTPFASESKQETALRIVHW-RKSLRIPASQR--VPTVALDLIRKLLCDKEQRIG---F
||| ||..|||             .| |||| ||..|| ||| |||  .|  ||   |..  . .|  |..    |.. | |||..||||.|.|.|   .
VGTPDYISPEVLQAMEDDGKGRYGPECDWWSVGVCMYEMLYGETPFYADSLVETYGKIMNHCKNHLSFPDDPKWDVSEEAKDLICQLLCDREERLGRNGY

DEIIAHPFF
... .||||
EDFKCHPFF
Kinase 84263.m00173.AA MAST 282-383 37 4.1e-31 91.77 In-house 224-337 (337) Show / Hide 
Range on Protein: 282-383
Range on HMM: 224-337/337
Sequence Identity: 37% (44 aa)

QRSSIVGTIDYVAPEVILGEA---PSVESDWWSFGVILYEFLYGFTPFASESKQE-TALRIVHWRKSLRIPAS------QRVPTVALDLIRKLL-CDKEQ
|  ...|| || |||||||.    ..|  |||| |.|.|||| | .||  .. .| .   |..  . .  |          .. .| |||.|||  .  .
QNKQCCGTPDYIAPEVILGQGTYGKPV--DWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKK

RIGFD---EIIAHPFF
|.|.    ||  ||||
RLGANGADEIKQHPFF
Kinase 84263.m00173.AA CRIK 287-383 34 5.6e-27 82.76 In-house 162-272 (272) Show / Hide 
Range on Protein: 287-383
Range on HMM: 162-272/272
Sequence Identity: 34% (38 aa)

VGTIDYVAPEVI--LGE------APSVESDWWSFGVILYEFLYGFTPFASESKQETALRIVH------WRKSLRIPASQRVPTVALDLIRKLLCDKEQRI
||| ||.||||   . .         |. |||| |.| ||  .| |||.  .  .|   |         .. |  |..  |   ..|||. |||.. .|.
VGTPDYMAPEVLQTMNGYKLSKGMYGVDCDWWSMGIIAYEMMCGKTPFHEDNMHRTYSNIMNHCEESHFQRFLSFPDDPKVSPNYRDLIQSLLCNQSKRL

GFDEIIAHPFF
..  .  ||||
KYEQLCCHPFF
Kinase 84263.m00173.AA GEK 287-383 39 9.8e-26 83.01 In-house 162-269 (269) Show / Hide 
Range on Protein: 287-383
Range on HMM: 162-269/269
Sequence Identity: 39% (43 aa)

VGTIDYVAPEVI--LGEAP---SVESDWWSFGVILYEFLYGFTPFASESKQETALRIVHWRKSLRIPASQR---VPTVALDLIRKLLCDKEQRI---GFD
||| ||..||..  ...       | |||| ||..||.||| ||| .||  ||  .|....  . .|. .    |.  | ||||.|.| .|.|.   | .
VGTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKDHFQFPSQETDWDVSEEAKDLIRQLICSQEHRLGRNGIQ

EIIAHPFF
.   ||||
DFKKHPFF
Kinase 84263.m00173.AA TyrKc 100-383 20 1.7e-11 -36.98 SMART 1-280 (280) Show / Hide 
Range on Protein: 100-383
Range on HMM: 1-280/280
Sequence Identity: 20% (62 aa)

FNYIKLIGRGGFADVWLVTDKNAQIYALKIIRKADVILNDQVQSVINERNILSVA--NNNWIVNLHSSFQDN-------DHLYLLLDFVQGGDLMNAL-V
   .| .|.| |  |.. | |  .  | | ...        ..  ..| .|..    ..  ||.|.    .        . |.... .. .||| . |  
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

KINTFPYPVARFFAGEIVLALHYIHQLGYVHSDVKPDNILINSDGHIKLTDFGIASSYNKVDNDYNNLLINSQDLLIDSSSIVSTANNRHHRQRSSI-VG
. .... .    |.  |     |.|. ...| |    |.|.......| .||| .      |.                   .|.   |.   ...  . 
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG-----------------ESKDYYRKKEHKGGKTML

TIDYVAPEVILGEAPSVESDWWSFGVILYEFL-YGFTPFASE----SKQETALRIVHWRKSLRIPASQRVPTV----ALDLIRKLLC-----DKEQRIGF
 |   |||.|     . .|| ||||| ..| . || .|   .     . . ... |  .. ...|..   | .    . | . ..       | |.|  |
PIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-P-MSFVCCPDEMYQIMKQCWHEDPEDRPTF

DEIIAHPFF
 ||  | .|
SEI--HECF
Kinase 84263.m00173.AA Pkinase_C 401-444 31 1e-06 26.73 Pfam 1-46 (46) Show / Hide 
Range on Protein: 401-444
Range on HMM: 1-46/46
Sequence Identity: 31% (15 aa)

QVTDPLDTQHFD-EFTVVPEEL--RAASCLSKLASFAFLGFSFKAKP
||..|.||..|| |||  | ..     . .|. .  .| ||....  
QVKSPTDTSNFDPEFTDEPPMDTPPDWR-MSSGDQEPFRGFTYVNPD
Kinase 84263.m00173.AA S_TK_X 384-442 20 4.2e-05 20.34 SMART 1-79 (79) Show / Hide 
Range on Protein: 384-442
Range on HMM: 1-79/79
Sequence Identity: 20% (17 aa)

KGFDFNNYQA----NKPPMRPQVT----DPLDTQHFD-EFTVVPEELRAASCLSKLASF-------------AFLGFSFKA
.|.|... ..     .|| .|...    .| ||  || |||  .    .  . . | .               |.||....
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM--LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF