Gene 81174.m00088 (T.vaginalis)
81174.m00088
Species: T.vaginalis
Alias: 81174.m00088, TvagK0362
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| 81174.m00088.AA | Protein | None | 405 | None | Fasta, JSON |
| 81174.m00088.kin_dom | Protein Kinase Domain | None | 255 | None | Fasta, JSON |
Protein domains of 81174.m00088.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 81174.m00088.AA | AGC | 88-342 | 31 | 9.80000000001e-157 | 408.71 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 88-342 Range on HMM: 1-395/395 Sequence Identity: 31% (125 aa) FNIISVIGRGFYGKVMLVENK------YTKEICAMKTIHKAR---LIKEKKVHTVIAE------------RNILVKVN----------HPFIVN-IKYAF |... |||.| .|||.||. | |....||| . |.. ..|...|. ...| ||||.|.| |||||. .|.| FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF QNETK--LYIGMEYVP---------GG-ELFHMMQ---IVENLPMKAIRIYVAE-------VGLALEYIHS-LGIVYRD-LKPENILITAEGHIKLTDFG |.... ||. |||.| || |||...| .. ...|.| || . |||||.|| .||..|| |||||||....||||||||| QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG LAKVLPEDE------------------------------------------------GEDTTKTFCG--TNEYLPPEMIKREYYGAMIDWWA--LGILTY |.|... |. ..|.|.|||| | ||..||.. || |||. ||.| | LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY ELIYGDTPFVHKS----------KHKMYEKIC------NEEPHFP----------DNEDPNVVDFITKLLKKDPKKRAK----------LKDLKNHPFF |...| .|| ... ...|..||. |....|| .. .|. .|.|.|||.|||.|| ...||||.| EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF |
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| Kinase | 81174.m00088.AA | Akt | 88-342 | 44 | 8.60000000001e-119 | 381.38 | In-house | 1-264 (264) | Show / Hide |
Range on Protein: 88-342 Range on HMM: 1-264/264 Sequence Identity: 44% (119 aa) FNIISVIGRGFYGKVMLVENKYTKEIC-AMKTIHKARLIKEKKVHTVIAERNILVKVNHPFIVNIKYAFQNETKLYIGMEYVPGGELFHMMQIVENLPMK |... |.|.| .|||.||. | |... ||| . | ..|. ..| ...|||||...||||||| .|.||...|||. |.|..||||| .| . . . FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED AIRIYVAEVGLALEYIHSLGIVYRD-LKPENILITAEGHIKLTDFGLAK--VLPEDEGEDTTKTFCGTNEYLPPEMIKREYYGAMIDWWA-LGILTYELI .| |.||. ||.|. || .|.||| |||||||. ..|||.||||||.| .. .. |.||||||| |||.||... .. . |||. ||...||.. RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDH---DKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMM YGDTPFVHKSKHKMYEKICNEEPHFP--DNEDPNVVDFITKLLKKDPKKR----AK-LKDLKNHPFF .| || .. .|.|..|| |.. || |. .|. |.|..||.|||||| . ....|.||.| CGRPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF |
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| Kinase | 81174.m00088.AA | SGK | 88-342 | 42 | 3.3e-113 | 351.06 | In-house | 1-283 (283) | Show / Hide |
Range on Protein: 88-342 Range on HMM: 1-283/283 Sequence Identity: 42% (121 aa) FNIISVIGRGFYGKVMLVENKYT------------------KEICAMKTIHKARLI-------KEKKVHTVIAER-NILVKVNHPFIVNIKYAFQNETKL | ...||| | .|||..|. | . . . ||| . |. | | |.. . ||| .||....|||||| .||||...|| FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL YIGMEYVPGGELFHMMQIVENLPMKAIRIYVAEVGLALEYIHSLGIVYRDLKPENILITAEGHIKLTDFGLAK--VLPEDEGEDTTKTFCGTNEYLPPEM | |.|| |||.| .| .| |.|.||. .|||| ||. |.|||||||||| ..||..||||||.| . . .|||.||||| ||| ||. YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGI----KTNDTTFTFCGTPEYLAPEV IKREYYGAMIDWWALGILTYELIYGDTPFVHKSKHKMYEKICNEEPHFPDNEDPNVVDFITKLLKKDPKKRAKLK----DLKNHPFF .. . .. ||| ||.. ||..|| || .. | ||..| |.. .| . . | |. ||.|||||| | . |||||| LRKQPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF |
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| Kinase | 81174.m00088.AA | AktR | 88-342 | 41 | 5.3e-112 | 378.4 | In-house | 1-268 (268) | Show / Hide |
Range on Protein: 88-342 Range on HMM: 1-268/268 Sequence Identity: 41% (111 aa) FNIISVIGRGFYGKVMLVENK-YTKEICAMKTIHKARLIKEKKVHTVIAERNILV-KVNHPFIVNIKYAFQNETKLYIGMEYVPGGELFHMMQIVENLPM | .. ..|.| .|||.||. | .... ||| |.| .|.... | .| ||||. ..||||||. .|.||...||.. |||.||||||.. . . . FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE KAIRIYVAEVGLALEYIHSL-GIVYRDLKPENILITAEGHIKLTDFGLAKVLPEDEGEDTTKTFCGTNEYLPPEMIKR-EYYGAMIDWWALGILTYELIY . .|.| |.. ||||| |. |.||||||||||. .||.|.|||||.| .. .. ......||||.||..||||.. . .. ..||||.||. ||... EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT GDTPFVHKSKHKMYEKICNEE-PHFPDNEDP--NVVDFIT-KLLKKDPKKRAK-----LKDLKNHPFF | .|| ||.. |..|| ... ||..... . |.|. |||.|.|.|| . ...|.||.| GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF |
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| Kinase | 81174.m00088.AA | PKA | 88-342 | 44 | 3.7e-103 | 349.02 | In-house | 1-263 (263) | Show / Hide |
Range on Protein: 88-342 Range on HMM: 1-263/263 Sequence Identity: 44% (118 aa) FNIISVIGRGFYGKVMLVENKYTKEICAMKTIHKARLIKEKKVHTVIAERNILVKVNHPFIVN-IKYAFQNETKLYIGMEYVPGGELFHMMQIVENLPMK |.|| ..|.| .|.|||. .| .....|||.. |.. ...| |. |. |.||| ..|||||. .. ||....|| ||||||||.|. .. . .. . FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP AIRIYVA-EVGLALEYIHSLGIVYRDLKPENILITAEGHIKLTDFGLAKVLPEDEGEDTTKTFCGTNEYLPPEMIKRE-YYGAMIDWWALGILTYELIYG ..|.| .. |||||.||. |.||||||||||| .||||.|||| || . . |.| ||| |||.||.|... .| .|||||||| ||. | HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD-----RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAG DTPFVHK--SKHKMYEKICNEEPHFPDNEDPNV---VDFITKLLKKDPKKRA---KL--KDLKNHPFF .|| . .. ..|||||| . || . |... |.| ||| .|..|| | | |||..| YPPFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF |
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| Kinase | 81174.m00088.AA | S_TKc | 88-342 | 35 | 6.7e-97 | 329.15 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 88-342 Range on HMM: 1-231/231 Sequence Identity: 35% (97 aa) FNIISVIGRGFYGKVMLVENKYTKEICAMKTIHKARLIKEKKVHTVIAERNILVKVNHPFIVNIKYAFQNETKLYIGMEYVPG--GELFHMMQIVEN--- . |. .||.| .|||... .| |..|.|.| |. ... |..|| | .||.||.....||. ..||. |||..| |.||.... YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ---LPMKAIRIYVAEVGLALEYIHSLGIVYRDLKPENILITAEGHIKLTDFGLAKVLPEDEGEDTTKTFCGTNEYLPPEMIKREYYGA-MIDWWALGILT .| .| |.... .||||.||.||..|||||||||.. |||..|||||..| .||||| .|..||.. || .|||..|.. RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL YELIYGDTPFVHKSKHKMYEKICNEEPHFPDNEDPNVVDFITKLLKKDPKKRAKLKDLKN-------HPFF ||...| .|| ..|..||. .| . ||| |.|.|||.|| .. . ||.| YEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | 81174.m00088.AA | RSK | 91-342 | 39 | 5.9e-95 | 321.76 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 91-342 Range on HMM: 1-278/278 Sequence Identity: 39% (109 aa) ISVIGRGFYGKVMLVENK---YTKEICAMKTIHKARLIKEKK-VHTVIAERNILVKVN-HPFIVNIKYAFQNETKLYIGMEYVPGGELFHMMQIVEN--- ..| |.| |||| |. . |. | ||| ..|| ... .| . .. .||||| .. |||||. .|||| |.|||. |||..||||| | . LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC LPMKAIRIYVAEVGLALEYIHSLGIVYRDLKPENILITA---EGHIKLTDFGLAKVLPEDEGEDTTKTFCGTNEYLPPEMIK----REYYGAMIDWWALG . . ..| ||. ||.|..|..||..||||||||| . ||||||||||..| .. |... |.|||.| ||..|||.| .. ... ||| || FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQ-WTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG ILTYELIYGDTPFVH---KSKHKMYEKICNEE--PHFP--DNEDPNVVDFITKLLKKDPKKRAK-----LKDLKNHPFF .| ||. | .|| . ..... ..|.. . . .| .. .. |.|.|.|..||.|| . ....|.||.| VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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| Kinase | 81174.m00088.AA | MAST | 88-342 | 32 | 5.5e-93 | 284.37 | In-house | 1-337 (337) | Show / Hide |
Range on Protein: 88-342
Range on HMM: 1-337/337
Sequence Identity: 32% (111 aa)
FNIISVIGRGFYGKVMLVENKYTKEICAMKTIHKARLIKEKKVHTVIAERNILVKVNHPFIVNIKYAFQN--ETKLYIGMEYVPGGELFHMMQIVE-NLP
|..| .|..| ||.| ||..| |... |||.| . .|. . | .|..|||||. . ||.|.. |.|| ...|.. |||. || .. .. . ..|
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP
MKAIRIYVAEVGLALEYIHSLGIVYRDLKPENILITAEGHIKLTDFGLAKV--------LPED---------------EGEDTTKTF-------------
..|.|| |.|||.|| ||| |||||.|.||.. ||||||||||.|| ..|. . ...|
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDKTTNHYEGYFNTNIFGKNHFNEYHIQKNYQQFQQDFGINGNTNKN
----------------------------CGTNEYLPPEMIKREY-YGAMIDWWALGILTYELIYGDTPFVHKSKHK-MYEKICN--EEPHFPDNEDPN--
||| .|..|| | .. ||. .|||..|| ||.. | .||. . . ..| | .| .|. .|||
QIQQQQEQPQCQQQNEMRPHNIHQNKQCCGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDD
------VVDFITKLLKKDPKKR--AK-LKDLKNHPFF
| | ||| ..|||| |. .. |.||||
DCMSPEAQDLIKKLLQPNPKKRLGANGADEIKQHPFF
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| Kinase | 81174.m00088.AA | Ciliate-E2 | 88-342 | 24 | 1.3e-83 | 284.08 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 88-342 Range on HMM: 1-365/365 Sequence Identity: 24% (91 aa) FNIISVIGRGFYGKVMLVENKYTKE-----------------------ICAMKTIHKARLIKEKKVHTVI----------AERNILVKVNHPFIVNIKYA ...| .||.| .|.| ..... ... | |||...| .. |.. .. |.||| ..|||.|...... YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC FQ--NETKLYIGMEYVPGGELFHMMQIV-----------ENLPMKAIR---------------IYVAEVGLALEYIHSLG-IVYRDLKPENILITAEGHI || .....|. |||. ||.||. ... ... .| |. |.|.. |||||.|| . |..||.||||||. | FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I KLTDFGLAKVLPEDEGE-----------------------------DTTKTFCGTNEYLPPEMIK---------REYYGAMIDWWALGILTYELIYGDTP |..||||.| . .|. . ....|.||| .|..||... ...|. ..|.|.||.. ||...| .| KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP FVHKSKHKMYEKICNEEPHFP------------------DNEDPNVVDFITK----LLKKDPKKRAK-LKDLKNHPFF | ...|.. . || .. .... |.| | .|.|||.|| ....|||.| F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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| Kinase | 81174.m00088.AA | Ciliate-E2-Unclassified | 88-342 | 26 | 2.4e-83 | 283.2 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 88-342
Range on HMM: 1-352/352
Sequence Identity: 26% (93 aa)
FNIISVIGRGFYGKVMLVENKYTKEICAMKTIHKARLIKEKKVHTV---------IAERN-------------ILVKVNHPFIVNIKYAFQNETKLYIGM
..|| .||.| .||| ....| .|.. |||...|.. .| |.. .. . ... ||. .|||||. |.||.. ..|| |
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM
EYVPGGELFHMMQIVEN-----------------LPMKAIR-----IYVAEVGLALEYIHSLG-IVYRDLKPENILITAEG---HIKLTDFGLAKVLPED
||..||.|. .... .. .. .... | |.. ..|||.|. . |..||.||||||.. .| .||..|||..| . ..
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN
EG-------------EDTTKTFCGTNEYL----PPEMIKR-EYYG---AMIDWWALGILTYELIYGDTPFVHKSKHK----------------MYEKICN
.. .. ..|||||..|. .||.... .|.. ..|.|.||.. ||...| || ... . .|..|..
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ
E------EPH--FPDNEDPNVVDFIT----KLLKKDPKKRAKLKDLKNHPFF
.|. .|.. .|.. |||. |.|||.|.|| .....|||.|
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
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| Kinase | 81174.m00088.AA | Pkinase | 88-342 | 31 | 7.7e-81 | 279.67 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 88-342 Range on HMM: 1-293/293 Sequence Identity: 31% (95 aa) FNIISVIGRGFYGKVMLVENKYTKEICAMKTIHKARLIKEKKVHTVI-AERNILVKVNHPFIVNIKYAFQNETKLYIGMEYVPGG----ELFHMMQ---- . |...||.| .|.| . .| | .| |.|.| | . ..|... . .| |. ..|||.|| ....|......|. |||..|| .||.... YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH -IVENLPMKAIRIYVAEVGLALEYIHSLGIVYRDLKPENILITAEGHI----KLTDFGLAKVLPEDEGEDTTKTFCGTNEYLPPEMIK-REYYGAMIDWW . .... .. |. .. .|||.|| ||..|||||||||| .||| |..||||||.. . ....||||| .|..|| |. ..||| .|.| GCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNSMTTFCGTPWYMAPEVIRGGQYYGPKVDMW ALGILTYELIYGDTPFVHK------SKHKMYEKICNEEPHFPDNED---------------------PNVVDFITKLLKKDPKKRAKLKDLKNHPFF ..|.. ||.. | .|| .. .. .|...| ..||. .. .. |||...|.|||||| .....||.| SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | 81174.m00088.AA | MAST | 88-235 | 46 | 2.9e-64 | 205.96 | In-house | 1-148 (334) | Show / Hide |
Range on Protein: 88-235 Range on HMM: 1-148/334 Sequence Identity: 46% (69 aa) FNIISVIGRGFYGKVMLVENKYTKEICAMKTIHKARLIKEKKVHTVIAERNILVKVNHPFIVNIKYAFQNETKLYIGMEYVPGGELFHMMQIVENLPMKA |..| .|..| |||| ||..| |... |||.| |. .|. . |..|..||||| . ||.|.. |.|| ...|.. |||. || ... .... ... FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM IRIYVAEVGLALEYIHSLGIVYRDLKPENILITAEGHIKLTDFGLAKV ..|.||. |.|||.|| ||| |||||.|.||...||||||||||.|| AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSKV |
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| Kinase | 81174.m00088.AA | MAST | 249-342 | 34 | 4.5e-29 | 90.61 | In-house | 225-334 (334) | Show / Hide |
Range on Protein: 249-342 Range on HMM: 225-334/334 Sequence Identity: 34% (38 aa) CGTNEYLPPEMIKREY-YGAMIDWWALGILTYELIYGDTPFVHKSKHKMYEKICNEE---PHFPDNEDPN--------VVDFITKLLKKDPKKR--AK-- ||| .|..|| |... .| .|||..|| ||.. | .||. .. . ...| |.. .|. .|.| . | | ||| ||.|| |. CGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRLGANNG LKDLKNHPFF .. |.|||| ADEVKQHPFF |
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| Kinase | 81174.m00088.AA | TyrKc | 88-342 | 20 | 2.6e-16 | 41.04 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 88-342 Range on HMM: 1-280/280 Sequence Identity: 20% (61 aa) FNIISVIGRGFYGKVMLVENKYTKEICAMKTIHKARLIKEKKVHTVIAERNILVKV--NHPFIVNIKYAFQNE-------TKLYIGMEYVPGGELFHMMQ . ..|.|..|.|.. . | . .| |.... . . | .|. |. .|| ||.. . . |.| |||.|.| | . . ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR IVEN-LPMKAIRIYVAEVGLALEYIHSLGIVYRDLKPENILITAEGHIKLTDFGLAKVLPED-----EGEDTTKTF-CGTNE-----YLPPEMIKREYYG .. |.|| . . ||.|| ... ||| |.|.......| .||||.. . .| ... .|. |.. ..|| |. . KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT AMIDWWALGILTYELI-YGDTPFVH-----KSKHKMYEKICNE-EPHFPDN--------EDPNVVDFITKLLKKDPKKRAKLKDLKNHPFF | |. |.. .|. ||..| .| ..|.. . . |.| . . . ... . ||..| ... | .| TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF |
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| Kinase | 81174.m00088.AA | S_TK_X | 343-402 | 22 | 9.5e-12 | 46.27 | SMART | 1-79 (79) | Show / Hide |
Range on Protein: 343-402 Range on HMM: 1-79/79 Sequence Identity: 22% (18 aa) NGLKFEDVLA--LKVKPPFRPRIG----SDRSVKNFDSEFTKEACIDSTA--AIVETNGA-----------FTGFSYIA |. ...... ...|||.|.| |.. ..||| |||.|. .. . ........ | ||.|.. RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF |
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| Kinase | 81174.m00088.AA | Pkinase_Tyr | 88-247 | 24 | 2e-10 | 35.91 | Pfam | 1-172 (270) | Show / Hide |
Range on Protein: 88-247
Range on HMM: 1-172/270
Sequence Identity: 24% (43 aa)
FNIISVIGRGFYGKVMLVENK----YTKEICAMKTIHKARLIKEK-KVHTVIAERNILVKV-NHPFIVNIKYAFQ-NETK--LYIGMEYVPGGELFHMMQ
.. ..|.| .|.|.. . | || .| |.. | .| . ..| .|. . .|| ||. . . .|| |||.|.| | . .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR
I----VENLPMKAIRIYVAEVGLALEYIHSLGIVYRDLKPENILITAEGHIKLTDFGLAKVLPEDEGED-TTKT
..|.|| . . ... ..|| .| ... ||| |.|.| ....| .|||||. . ..... ....
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRG
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| Kinase | 81174.m00088.AA | Pkinase_C | 362-404 | 29 | 9.7e-08 | 30.55 | Pfam | 1-46 (46) | Show / Hide |
Range on Protein: 362-404 Range on HMM: 1-46/46 Sequence Identity: 29% (14 aa) RIGSDRSVKNFDSEFTKEACIDS----TAAIVETNGAFTGFSYIAGD .. |.. . ||| |||.|.. |. . . . .| ||.| . | QVKSPTDTSNFDPEFTDEPPMDTPPDWR-MSSGDQEPFRGFTYVNPD |
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| Kinase | 81174.m00088.AA | Pkinase_Tyr | 272-300 | 32 | 0.387035 | 4.48 | Pfam | 198-228 (270) | Show / Hide |
Range on Protein: 272-300 Range on HMM: 198-228/270 Sequence Identity: 32% (10 aa) WALGILTYELIY-GDTP-FVHKSKHKMYEKI |. |.| .|.. |..| . | . .||.| WSFGVLMWEIFTYGEQPTYPGMSNEEVYEYI |
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