Gene 97090.m00173 (T.vaginalis)

97090.m00173

Species: T.vaginalis
Alias: TvagK0694, 97090.m00173
External Links:
Annotation:

Classification

Group: Other
Family: NEK
Subfamily: NEK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
97090.m00173.AA Protein None 481 None Fasta, JSON
97090.m00173.kin_dom Protein Kinase Domain None 256 None Fasta, JSON

Protein domain

Protein domains of 97090.m00173.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 97090.m00173.AA NEK 6-261 33 2.8e-101 342.8 In-house 1-286 (286) Show / Hide 
Range on Protein: 6-261
Range on HMM: 1-286/286
Sequence Identity: 33% (96 aa)

FLQEKVLGKGSYGTVYKAKRIANDQS-----YAVKIVNTAGMCKRELEDSV-NEIRLMASFNSPFIISFYEAFALQT--RLCVITEYAR-LGDLSKL---
.   |..|.||.|.|||..|. . .      |. | .|. .|  .| .... ||.|. .. ..| |...|..|  .   .|| . ||.   |||...   
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS

IDRRKRTNRPLLEDDIWRFLIQVTEGLRVLHEK-----GVVHRDIKSANLLLCAPDL----VKIGDLGISTILHSH-QFAKT-QIGTPLYLAPEIWRRRP
| ..|  . .. |. ||...||   .|. .|..      ..|||||..|. | . .     |||||.||| .| .  ..|.| |.||| |..||... .|
IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNKP

YDAKCDMWSLGVVLYEMLNFSF--PFIAN--STEELGRRILAG-RIGPIRNG--YSSEIQNIVNLLLQTNPDNRPSSEELMNMPCI
|. |.|.||||.|||||  ..   || |.  . ..|  .|  |    ||     ||.. ||.....|| .|..||| .....||.|
YNNKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase 97090.m00173.AA S_TKc 6-261 28 1.8e-85 291.2 SMART 1-231 (231) Show / Hide 
Range on Protein: 6-261
Range on HMM: 1-231/231
Sequence Identity: 28% (76 aa)

FLQEKVLGKGSYGTVYKAKRIANDQSYAVKIVNTAGMCKRELEDSVNEIRLMASFNSPFIISFYEAFALQTRLCVITEYARL--GDLSKLIDRRKR--TN
.   ...|||..|.|||.. .  .. .|.||..         |.  .||... . . |.|. .|..|   ..|....||.    ||| ..|..|.|  ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

RPLLEDDIWRFLIQVTEGLRVLHEKGVVHRDIKSANLLLCAPDLVKIGDLGISTILHSHQFAKTQIGTPLYLAPEIWRRRPYDA-KCDMWSLGVVLYEML
.|. | ...... |. ..|  .|..|..|||.| .|.||.    .||.| |....|      .|..||| |.|||.    .|.  |||.||.|..|||||
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

NFSFPFIANSTEELGRRILAGRIGPIRNGYSSEIQNIVNLLLQTNPDNRPSSEELMN-------MPCI
    ||     ... ..|.           |.|  .... .|| .|..||.  |...       .| .
CGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 97090.m00173.AA NEK1 6-261 35 3.1e-72 246.28 In-house 1-276 (276) Show / Hide 
Range on Protein: 6-261
Range on HMM: 1-276/276
Sequence Identity: 35% (98 aa)

FLQEKVLGKGSYGTVYKAKRIANDQSYAVKIVNTAGMCKRELEDSVNEIRLMASFNSPFIISFYEAFALQTR--LCVITEYARLGDLSKLIDRRKRTNRP
..  |..|.||.| ....|. .  | |. |  |   | . | |.|.||  . |    | |....|.| .  .  |  . ||.  ||| . | |.|| . .
YHYIKQIGEGSFGKAWLVKHKEDGQHYVIKEINVMKMQEKEREESMNEVAILAKMKHPNIVKYKESFEENGCGILYIVMEYCDGGDLMQKINRQKRKGKL

LLEDDIWRFLIQVTEGLRVLHEKGVVHRDIKSANLLLC--APD---------------LVKIGDLGISTIL-HSHQFAKTQIGTPLYLAPEIWRRRPYDA
  || |  . .|   .|   | . . |||||| |. |     .               |||.|| ||. .| |.  .|.| |||| || |||.  .||. 
FSEDQIMHWFCQICLALNHIHDRKILHRDIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGIARMLNHTMEYACTCIGTPYYLSPEICQNKPYNN

KCDMWSLGVVLYEMLNFSFPFIANSTEELGRRILAGRIGPIRNGYSSEIQNIVNLLLQTNPDNRPSSEELMNMPCI
| |.||||.|||| .  . || ||.   |  .|. |.. || . || |.|. |  ... || .|||   .   | |
KSDIWSLGCVLYELCTLKHPFEANNWKNLVLKICQGTYPPIPPHYSYELQSLVSQMFKRNPRHRPSVNQILERPFI
Kinase 97090.m00173.AA Pkinase 6-261 24 1e-69 242.74 Pfam 1-293 (293) Show / Hide 
Range on Protein: 6-261
Range on HMM: 1-293/293
Sequence Identity: 24% (73 aa)

FLQEKVLGKGSYGTVYKAKRIANDQSYAVKIVNTAGMCKRELEDSVN--EIRLMASFNSPFIISFYEAFALQTRLCVITEYARLG----DLSKLIDRRKR
.  ....|.||.|.|||.... . . .||||..  .  . ...  ..  ||..|...|.|.|. .|..|   .......||.. |    ||. .| .  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--W

TNRPL--LEDDIWRFLIQVTEGLRVLHEKGVVHRDIKSANLLLCAPDLV----KIGDLGISTI--LHSHQFAKTQIGTPLYLAPEIWR-RRPYDAKCDMW
 ....   |... ... |. .||  .|..|..|||.|..|.|.   . .    ||.| |..    . . . ..|  ||| |.|||. | ...|. |.|||
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SLGVVLYEMLNFSFPFIAN----STEELGRRILAGRIGPIRNGYS-----------------------SEIQNIVNLLLQTNPDNRPSSEELMNMPCI
|.|..|||||.  .||       .  .   .|   . .|..  ..                       .| . ... .|. .|  ||. |.... | .
SCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 97090.m00173.AA ULK 6-261 26 4.3e-68 232.54 In-house 1-324 (324) Show / Hide 
Range on Protein: 6-261
Range on HMM: 1-324/324
Sequence Identity: 26% (87 aa)

FLQEKVLGKGSYG-TVYKAKRIAN---DQSYAVKIVNTAGMCKRELEDS--------VNEIRLMASFN---SPF--IISFYEAFALQTR--LCVITEYAR
.   ..|||||.| .|||.. . .   .| .|.|...  .| | ..|.          |||..|  ..   .|.  |. .|. |  ..   .. |.||  
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

LGDLSKLIDRRKR-----TNRPLLEDDIWRFLIQVTEGLRVLHEKGVVHRDIKSANLLLCAPD------------LVKIGDLGISTILHS----HQFAKT
 |||...| ..|.     ... | |. .  |..|  .|.. ||.....||||| .|.|.  ..             .||.| | . .. .     |  .|
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

QI------GTPLYLAPEIWRRR----PYD-AKCDMWSLGVVLYEMLNFSFPFIAN--STE----ELGRR-------ILAGRIGPIRNG----YSSEIQNI
.       ||||| ||.|. ..    ||. .|||.||||...||||  . || ..  ...    .| .        |    | .  ..     |.|....
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDL

VNLLLQTNPDNRPSSEELMNMPCI
   .|| ... | | ||. |.|..
IRRMLQYDEKDRISWEEIFNHPWF
Kinase 97090.m00173.AA ULK 6-261 26 2.4e-66 226.75 In-house 1-329 (329) Show / Hide 
Range on Protein: 6-261
Range on HMM: 1-329/329
Sequence Identity: 26% (86 aa)

FLQEKVLGKGSYGTVYKAKRIAN----DQSYAVKIVNTAGMCKRELEDS--------VNEIRLMASFN----SPF----IISFYEAFALQTR--LCVITE
.   ..|||||.|.|||.. . .    .. .|.|..    | . . |.          |||..|   .    ...    |. .|. |  ..   .  |.|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YARLGDLSKLIDRRKR------TNRPLLEDDIWRFLIQVTEGLRVLHEKGVVHRDIKSANLLLCAPD------------LVKIGDLGISTILHSH----Q
|   |||...| ..|.      ... | |. .  |..|  .|.. ||.....||||| .| |.  ..             .||.| | .  . .     |
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

FAKTQI------GTPLYLAPEIWRRR----PYD-AKCDMWSLGVVLYEMLNFSFPFIANSTEELGRRILAGRIG------------PIR-------NGYS
 ..|.       ||||| ||.|. ..    ||. .|||.||||...||||    || |.  ...  .|.   |             |..       .  |
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

SEIQNIVNLLLQTNPDNRPSSEELMNMPCI
.|....   .|| ... | | ||| |.|..
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 97090.m00173.AA CAMK 11-261 17 4.7e-66 211.57 In-house 1-425 (425) Show / Hide 
Range on Protein: 11-261
Range on HMM: 1-425/425
Sequence Identity: 17% (76 aa)

VLGKGSYGTVYKAKRIAND------------QSYAVKIVNTAGMC--------------------------KRELEDSVNEIRLMAS-------FNSPFI
.||.||.|.|...... .             | .|.||...  .                            . ..   .||..| .        . | |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

ISFYEAFAL-------------------QTRLCVIT---EYARLG----D-LSKLIDRRKRTN----------RPLLEDDIWRFLIQVTEGLRVLHEKGV
|..||..                     ..... ..   ||.  |    | ............          . . |..  |.  |. .... .|....
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHRDIKSANLLLCAPD-----------------LVKIGDLGISTILHS------------------------HQFAKTQIGTPLYLA-PEIWRR------
||||.|  |.||.  .                  .|| | | .... .                         |  ||. ||| | | ||. ..      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------RPYDAKCDMWSLGVVLYEMLNFSFPFIAN-------------STEELGRRILAGRIGPI---------------RNGYSSE--------IQN
        ..|. ||||||.||.|| ||   .|| .              . .|| ..|..|.   .                .. | |         ..
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

IVNLLLQTNPDNRPSSEELMNMPCI
 .. .||..|..|.. |. .| | .
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 97090.m00173.AA Ciliate-E2 6-261 23 7.8e-62 211.04 In-house 1-365 (365) Show / Hide 
Range on Protein: 6-261
Range on HMM: 1-365/365
Sequence Identity: 23% (88 aa)

FLQEKVLGKGSYGTVYKAKRIANDQSY------------------AVKIVNTAGMCKRELEDSVNEIRLM----------------ASFNSPFIISFYEA
.   |..|.|..|.|||.|.. ... .                  ..||..   | |...|   .||..|                 . |.|.|| .||.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FA--LQTRLCVITEYARLGDLSKLID--RRKRTNR-----PLLEDDIWRFLIQVTE---------------GLRVLHEKG-VVHRDIKSANLLLCAPDLV
|    .. .  ..||.  ||| ..|   . ||..      .. |  | ..  |...               .|. ||.|. ..|||||  |.|.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KIGDLGISTILHSH--------------------------------QFAKTQIGTPLYLAPEIWRRRP---------YDAKCDMWSLGVVLYEMLNFSFP
|| |.|.|....                                  . ..|..||| |.|||| .. .         || |||.|||||.|||||   .|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FIANSTEELGRRILAGRIG-P----------------IRNGYSSEIQNIVNL----LLQTNPDNRPS-SEELMNMPCI
|         . |. . |  |                . .  | | ... .     .|| .|..|..  |...| | .
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 97090.m00173.AA STE 7-261 22 1.1e-60 207.88 In-house 1-359 (359) Show / Hide 
Range on Protein: 7-261
Range on HMM: 1-359/359
Sequence Identity: 22% (82 aa)

LQE-KVLGKGSYGTVYKAKRI------ANDQS---------YAVKIVNTAGMCK---------------RELEDSVNEIRLMASFN--SPFIISFYEAFA
..  ...|||..||||||...       ...          .|.|..|     .                |...  .||..|  .|  .|.|. .| .. 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

LQ-------TRLCVITEYARLGDLSKLIDRRKRTNRPLL----------EDDIWRFLIQVTEG-LRVLHEKGVVHRDIKSANLLLCAPDLVKIGDLGIST
         . |... ||   | |...|.... ...||           |. | ... |. .| |  ||.....|||||.|| ||     ||. | |...
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

ILHSH-----------------QFAKTQIGTPLYLAPEIWRR------RPYDAKCDMWSLGVVLYEMLNFSFPFIANSTEELGRRILAG-----------
.| ..                 |  .| .||| . |||. ..       .||.|||.|||| .. ||..   |.   .  .   .|. .           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----RIGPIRN-------------------GYSSEIQNIVNLLLQTNPDNRPSSEELMN--MPCI
     . |. .                    .|.| .. .|. || .|..||....|..   | |
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 97090.m00173.AA CAMKL 6-261 28 1.3e-56 179.14 In-house 1-297 (297) Show / Hide 
Range on Protein: 6-261
Range on HMM: 1-297/297
Sequence Identity: 28% (84 aa)

FLQEKVLGKGSYGTVYKAKR-IANDQSYAVKIVNTAGMCKRELEDSV-------------NEIRLMASFN---SPFIISFYEAFALQTR------LCVIT
.  .|.|||||.|.|  |.  . . . .|.||..  ......  ..               ||..| ..|    | ||..|| .  ..       .. ..
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYARLGD--LSKLIDRRKRTNRPLLEDDIWRFLIQVTEGLRVLHEKGVVHRDIKSANLLLCAPD--LVKIGDLGISTILHS-----HQFAKTQIGTPLYL
||.  |.  |   |..... .... |..  |.  |. ...  .|..|.||||||  |.||   .   .|| | | |..         |. ||. |.| | 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEIWRR--RPYD-AKCDMWSLGVVLYEMLNFSFPFIAN--------STEELGRRILAGRIGP-IRNGYSSEIQNIVNLLLQTNPDNRPSSEELMNMPCI
||||  .  .|||  | |.||.||.|| |.   .|| .          . .| ..|  |   | | .  | . ...   .||.||. ||. ...|| |  
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 97090.m00173.AA NEK4 10-261 34 2.3e-56 193.57 In-house 5-257 (257) Show / Hide 
Range on Protein: 10-261
Range on HMM: 5-257/257
Sequence Identity: 34% (87 aa)

KVLGKGSYGTVYKAKRIANDQSYAVKIVNTAGMCKRELEDSVNEIRLMASFNSPFIISFYEAFALQTR--LCVITEYARLGDLSKLIDRRKRTNRPLLED
|| |||||| |.  .       | .| ..     .||  .   |..|.     | |... | .       |...  .   ||| .   ..|  |  | | 
KVVGKGSYGEVWLVRHRRDKKQYVMKKMFLKNASRRERKAAEHEAQLLSQLKHPNIVEYKESWEIENGQFLYIVMGFCEGGDLYRKLKQQK--NQFLEEY

DIWRFLIQVTEGLRVLHEKGVVHRDIKSANLLLCAPDLVKIGDLGISTILH-SHQFAKTQIGTPLYLAPEIWRRRPYDAKCDMWSLGVVLYEMLNFSFPF
 .    .|.  .|  .||| ..||| |  |. |    ..||||.||| .|  . ..||| |||| |. ||..  |||| | |.||||  .|||      |
QVVEWFVQIAMALQYMHEKHILHRDLKTQNIFLTKKNIIKIGDFGISRVLNNHCDMAKTMIGTPYYMSPECFGNRPYDYKSDIWSLGCCVYEMITLKHAF

IANSTEELGRRILAGRIGPIRNGYSSEIQNIVNLLLQTNPDNRPSSEELMNMPCI
 |     |  .|. |.  |.   || ..||.|  .|.  |..|||  ... || |
DAKDMNSLIYQIIQGQPPPMPPNYSQDLQNLVYQMLEKQPTKRPSIFDIFQMPYI
Kinase 97090.m00173.AA Ciliate-E2-Unclassified 6-261 23 3.1e-52 179.48 In-house 1-352 (352) Show / Hide 
Range on Protein: 6-261
Range on HMM: 1-352/352
Sequence Identity: 23% (84 aa)

FLQEKVLGKGSYGTVYKAKRIANDQSYAVKIVNTAGMCKRELEDS----------VNEIR-------------LMASFNSPFIISFYEAFALQTRLCVIT
.   |..|.|..|.|||.... ..| || |. . . ..|. .  .          .|..              .. ....|||. ....|  .  .. ..
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYARLGDLSKLID-------------RRKRTNRPLLEDDIW-----RFLIQVTEGLRVLHEKG-VVHRDIKSANLLLCAPD---LVKIGDLGISTILH--
||.. |||.. |              ....... . |  .      ... |. .||  ||.|. ..|||||  |.|.        .|| |.|||  .   
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

--------------SHQFAKTQIGTPLYL----APEIWRRRPYD----AKCDMWSLGVVLYEMLNFSFPFIANSTEE----------------LGRRILA
              ..| ..|..||| |.    |||. ..  ||     |||.|||||.|||||   .|| .|. |.                | . |..
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

GRIGPIR-------NGYSSEIQNIVN----LLLQTNPDNRPSSEELMNMPCI
. |            . | | ....|     .|. ||..|.. |...| | .
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 97090.m00173.AA Pkinase_Tyr 6-202 25 4e-24 82.31 Pfam 1-210 (270) Show / Hide 
Range on Protein: 6-202
Range on HMM: 1-210/270
Sequence Identity: 25% (53 aa)

FLQEKVLGKGSYGTVYKAKRI----ANDQSYAVKIVNTAGMCKRE--LEDSVNEIRLMASF-NSPFIISFYEAFA-LQTR--LCVITEYARLGDLSKLID
    |.||.|..|.|||..       ...  |||..   |  ...  .||  .|...| .. . | |...| .    .    .....||. .||| .   
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

RRKRTNRPLLEDDIWRFLIQVTEGLRVLHEKGVVHRDIKSANLLLCAPDLVKIGDLGISTILHSHQFA-KTQIGTPL---YLAPEIWRRRPYDAKCDMWS
...  ..||   |.  . .|. .|.  |..|. .|||.   | |.  .  |||.| | .  ...     ... |..|    .||| .. . .  | | ||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWS

LGVVLYEMLNF
 ||...|.. .
FGVLMWEIFTY
Kinase 97090.m00173.AA TyrKc 6-261 23 3.1e-19 71.13 SMART 1-280 (280) Show / Hide 
Range on Protein: 6-261
Range on HMM: 1-280/280
Sequence Identity: 23% (70 aa)

FLQEKVLGKGSYGTVYKAKRIANDQSYAVKIVNTAGMCKRELEDSVNEIRLMASF--NSPFIISFYEAFALQ-------TRLCVITEYARLGDLSKLIDR
   .|.|| | .|.|||.. .   .  ||| ..        .||  .|.|.| ..  . | |. .| .   |         |....||. .||| . . .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

RKRTNRPLLEDDIWRFLIQVTEGLRVLHEKGVVHRDIKSANLLLCAPDLVKIGDLGISTILHSH--------QFAKTQ-IGTP--L---YLAPEIWRRRP
....   |  .|   | .|. .| . ||.|...|||.   | |. ..  |||.| | |  ....           |..  |.   |    .||| .. . 
HRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

YDAKCDMWSLGVVLYEMLNF-SFPFIA-----NSTEELGRRILAGRIGPIRNG--------YSSEIQNIVNLLLQTNPDNRPSSEELMNMPCI
.  | | || ||...|.. .   |         | .|. ... .|.  |.            ..|. .|     . .|..||. .|.    |.
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF