Gene 88481.m00082 (T.vaginalis)

88481.m00082

Species: T.vaginalis
Alias: 88481.m00082, TvagK0397
External Links:
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
88481.m00082.AA Protein None 452 None Fasta, JSON
88481.m00082.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of 88481.m00082.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PH 88481.m00082.AA PH 9-107 19 3.6e-05 24.42 SMART 1-82 (82) Show / Hide 
Range on Protein: 9-107
Range on HMM: 1-82/82
Sequence Identity: 19% (19 aa)

EELTAPFIKKGTKFGFWHKRYCVLRLKEQKLLLYLNKERKIFDRMVKITPEIECLIDENRKHPSFTLKYPDSRPLRLSTPDISTLRIWVNAIRTMSIEN
 ..     ||.  .  |.||..||.   . |..| .|      .  .. |  .| ..|     .|.... |   . ..... .... |..||. .. .|
VIKEGWLYKKS--K-RWKKRWFVLFN--DCLYYYKDK------KPKGSIPLSDCTVRE-P---CFEIHH-DR-TYYFQCESEEEMQEWMQAIQKAIHNN
Kinase 88481.m00082.AA AGC 115-366 28 2e-137 357.62 In-house 1-395 (395) Show / Hide 
Range on Protein: 115-366
Range on HMM: 1-395/395
Sequence Identity: 28% (113 aa)

FIPINVIGRGYYGKVTLCEKK------STGQRYAIKSVHKSR---LMKAHKAITVINE------------RNTLMKTD----------HPFIVH-IYFAF
|  . |||.| .||| |..||      .||. ||.| . |..   ..| ..   ...|            || |.| .          |||||.  ...|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QNSSK--VYMGFEYVA--------GGDMAFHLHNLK-----KFEKHDVRLYIAE-------LALAIEYIHR-NNIIYRD-LKPENILMDETGSVKLTDFG
|. ..  .|.  ||.         ||.. ..||. .     .|.   .| |.||       ..||.||.|. ..||.|| |||||||.|| | .||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LVKDIAYSKG---------------------------------------------------AHSFCG--TPEYLAPEIIKSQKYGPKIDWWA--LGIVMY
| | .  ...                                                   ...|||  ||||.||||.    ||.  |||.  ||..||
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

SFLYGQTPWYDDNMD----------KLFKKII------SAPLEFP----------PDATSDEKDLIKNLLDRNPETRKD----------IRFLLHHPFF
 .|.|..| |.|| .          ..|.||.      . ...||          .  ... ||||| || ..|| |            .  .  ||.|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 88481.m00082.AA SGK 115-366 39 8.20000000001e-105 324.65 In-house 1-283 (283) Show / Hide 
Range on Protein: 115-366
Range on HMM: 1-283/283
Sequence Identity: 39% (111 aa)

FIPINVIGRGYYGKVTLCEKKST------------------GQRYAIKSVHKSRLM-------KAHKAITVINERNTLMKT-DHPFIVHIYFAFQNSSKV
|. ..||| | .||| . ..|..                  .. ||.|   |           |  ..  .  |||...|   |||||   .|||.  | 
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YMGFEYVAGGDMAFHLHNLKKFEKHDVRLYIAELALAIEYIHRNNIIYRDLKPENILMDETGSVKLTDFGLVK-DIAYSKGAHSFCGTPEYLAPEIIKSQ
|.  .|| ||.| .||   |.|  . .| | ||...|.|| |  .|||||||||||| |  | ..|||||| | .|. ...  .|||||||||||... |
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

KYGPKIDWWALGIVMYSFLYGQTPWYDDNMDKLFKKIISAPLEFPPDATSDEKDLIKNLLDRNPETR---K-DIRFLLHHPFF
 ..   ||| ||.|.| ..||  | |. |   .. .||. || .||  ..| .|||. || ..|. |   | | .    ||||
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase 88481.m00082.AA Akt 115-366 41 2.4e-102 327.96 In-house 1-264 (264) Show / Hide 
Range on Protein: 115-366
Range on HMM: 1-264/264
Sequence Identity: 41% (109 aa)

FIPINVIGRGYYGKVTLCEKKSTGQRY-AIKSVHKSRLMKAHKAITVINERNTLMKTDHPFIVHIYFAFQNSSKVYMGFEYVAGGDMAFHLHNLKKFEKH
|  ..|.|.| .||| |..||.|.. | |.|.  |... .  .   .. ||| | ...|||||  ...||.. | |.  .|. ||.  .||.  ..|   
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

DVRLYIAELALAIEYIHRNNIIYRD-LKPENILMDETGSVKLTDFGLVK-D-IAYSKGAHSFCGTPEYLAPEIIKSQKYGPKIDWWA-LGIVMYSFLYGQ
  | |.||. ||||. | .|||||| |||||||||..| ..|||||| | . | .   . .||||||||||||.. . .. . |||. ||.||| ...|.
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

TPWYDDNMDKLFKKIISAPLEFP--PDATSDEKDLIKNLLDRNPETRK-----DIRFLLHHPFF
 | |... ...|||| ..|..||  .    . ||||. || ..|. |      |.. .  ||.|
PPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 88481.m00082.AA S_TKc 115-366 33 8e-100 338.85 SMART 1-231 (231) Show / Hide 
Range on Protein: 115-366
Range on HMM: 1-231/231
Sequence Identity: 33% (91 aa)

FIPINVIGRGYYGKVTLCEKKSTGQRYAIKSVHKSRLMKAHKAITVINERNTLMKTDHPFIVHIYFAFQNSSKVYMGFEYVAG--GDMAFHLHNLKK---
.  ...||.| .||| .| .|.||...||| ..          .....|.. |.| .||.||..| .||. ...|| .||. |  ||.  .... ..   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FEKHDVRLYIAELALAIEYIHRNNIIYRDLKPENILMDETGSVKLTDFGLVKDIAYSKGAHSFCGTPEYLAPEIIKSQKYGP-KIDWWALGIVMYSF
   |   ..| |......|.||.|...||.|||||||||.||   .|..|||| . .      ..|||||.|.|||..   .||. |.|||..|...| .
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

LYGQTPWYDDNMDKLFKKIISAPLEFPPDATSDEKDLIKNLLDRNPETRKDIRFLLH-------HPFF
|.|..|..  .|...||||           ... ||.|...|...|| |  .  .|.       ||.|
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 88481.m00082.AA RSK-Unclassified 115-366 39 1.2e-91 288.13 In-house 1-283 (283) Show / Hide 
Range on Protein: 115-366
Range on HMM: 1-283/283
Sequence Identity: 39% (111 aa)

FIPINVIGRGYYGKVTLCEKKSTGQRYAIKSVHKSRLMKAHKAITVINERNTLMKTDHPFIVHIYFAFQNSSKVYMGFEYVAGGDMAFHLH--NLKKFEK
|| .  ||.|  ||| | .|| | | ||.|  ||.....  |   |. |.| .  |.|||||  |..|| . . |.  ||  |||.  ||     |.|  
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE

HDVRLYIAELALAIEYIHRNNIIYRDLKPENILMDETGSVKLTDFGLVKDI----------------------AYSKGAHSFCGTPEYLAPEIIKSQKYG
 ||| |..|  .| || |.  .|||||||.||...  | |.||||.| ..                         . .. ||||| ||||||.|.    .
DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCGHT

PKIDWWALGIVMYSFLYGQTPWYDDNMDKLFKKIISAPLEFP--PDATSDEKDLIKNLLDRNPETRK-----DIRFLLHHPFF
  .||| ||||||  | | .|.| .| . .|. |  ... ||       . .|||| || |||  |      |      ||||
KAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF
Kinase 88481.m00082.AA RSK 118-366 37 3.6e-89 302.56 In-house 1-278 (278) Show / Hide 
Range on Protein: 118-366
Range on HMM: 1-278/278
Sequence Identity: 37% (103 aa)

INVIGRGYYGKVTLCEKK---STGQRYAIKSVHKSRLMKAHK-AITVINERNTLMKTD-HPFIVHIYFAFQNSSKVYMGFEYVAGGDMAFHLHNLKK---
. | |.| |||| || |.    ||| || | ..|. .... | . ..  ||| |. .  |||||. . |||  .|.|.  ||. ||..  || . |    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FEKHDVRLYIAELALAIEYIHRNNIIYRDLKPENILMDE---TGSVKLTDFGLVKD-IAY-SKGAHSFCGTPEYLAPEIIK---SQK-YGPKIDWWALGI
|  .... |.||..||.|..|   ||.||||||||| |.    |..||||||. |   .  .. ...||.| ||.|||..|    |. ..   ||| ||.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

VMYSFLYGQTPWYD---DNMDKLFKKIISAP--LEFP--PDATSDEKDLIKNLLDRNPETRKD-----IRFLLHHPFF
.||  | |..| .    .| ....|.| ..   |..|  .  . . ||||. .| |.|. |       .  .. ||.|
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 88481.m00082.AA AktR 115-366 40 5e-88 298.75 In-house 1-268 (268) Show / Hide 
Range on Protein: 115-366
Range on HMM: 1-268/268
Sequence Identity: 40% (108 aa)

FIPINVIGRGYYGKVTLCEKK-STGQRYAIKSVHKSRLMKAHKAITVINERNTLM-KTDHPFIVHIYFAFQNSSKVYMGFEYVAGGDMAFHLHNLKKFEK
|  ....|.| .||| |..||  ... ||.|...|. . .  ..  .|.||| .  . .|||||  ...||. .| .   ||..||.. .|| . |||. 
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

HDVRLYIAELALAIEYIHRN-NIIYRDLKPENILMDETGSVKLTDFGLVK---DIAYSKGAHSFCGTPEYLAPEIIKS-QKYGPKIDWWALGIVMYSFLY
 ..| |.|.  ||.|| | . |||||||||||||.|| | ||.||||| |   ...|.  |.||||||||.|||.|.  . ..  .||||.||. |  ..
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GQTPWYDDNMDKLFKKIISAP-LEFPPD--ATSDEKDLIK-NLLDRNPE---T--RKDIRFLLHHPFF
|..| |..|   .|.||.. . ..||.    .|  ||||.  ||..||.   .  ....  .  ||.|
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 88481.m00082.AA Pkinase 115-366 30 2e-86 298.26 Pfam 1-293 (293) Show / Hide 
Range on Protein: 115-366
Range on HMM: 1-293/293
Sequence Identity: 30% (90 aa)

FIPINVIGRGYYGKVTLCEKKSTGQRYAIKSVHKSRLMKAHKAITVIN--ERNTLMKTDHPFIVHIYFAFQNSSKVYMGFEYVAGG----DMAFHLH--N
.  . .||.| .|.| .| .|.||...|.| . |.   |  | .| ..  |   . . .||.|| .| .|......|| .||. ||    | . ...  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

LKKF--EKHDVRLYIAELALAIEYIHRNNIIYRDLKPENILMDETGSV----KLTDFGLVKD--IAYSKGAHSFCGTPEYLAPEIIK-SQKYGPKIDWWA
 ..|  . .... |. ... ..||.|...||.|||||||||.|..| .    |..|||| |   .  .  ...|||||.|.|||.|. .|.||||.|.|.
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGIVMYSFLYGQTPWYDD------NMDKLFKKIISAPLEFPPDAT---------------------SDEKDLIKNLLDRNPETRKDIRFLLHHPFF
.|...| .| |..|....      ........| ..||.|. . .                     .. ||.||..|...|. |  .. .|.||.|
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 88481.m00082.AA PKA 115-366 41 8.8e-86 291.3 In-house 1-263 (263) Show / Hide 
Range on Protein: 115-366
Range on HMM: 1-263/263
Sequence Identity: 41% (110 aa)

FIPINVIGRGYYGKVTLCEKKSTGQRYAIKSVHKSRLMKAHKAITVINERNTLMKTDHPFIVH-IYFAFQNSSKVYMGFEYVAGGDMAFHLHNLKKFEKH
|  |...|.| .|.| || .|..|. ||.|   |..  .      |.||.| |. ..|||||   |. ||.... || .|||.||.|  .| . ..|   
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

DVRLYIA-ELALAIEYIHRNNIIYRDLKPENILMDETGSVKLTDFGLVKDIAYSKGAHSFCGTPEYLAPEIIKSQ-KYGPKIDWWALGIVMYSFLYGQTP
. ..|.| .  ||.||.|  |||||||||||||.|. | .|.|||| .| .       . ||||||||||||.|   .|  .|||||||. | .| | .|
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD--RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPP

WYDD--NMDKLFKKIISAPLEFPPDATSDE---KDLIKNLLDRNPETRK--------DIRFLLHHPFF
 ||.  .  ....||... ..||.  .||.   |||||.|| .... |         ||.   .|..|
FYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIK---NHKWF
Kinase 88481.m00082.AA Ciliate-E2 115-366 23 1.4e-79 270.66 In-house 1-365 (365) Show / Hide 
Range on Protein: 115-366
Range on HMM: 1-365/365
Sequence Identity: 23% (90 aa)

FIPINVIGRGYYGKVTLCEKKSTGQR-----------------------YAIKSVHKSRLMKAHKAITVI----------NERNTLMKTDHPFIVHIYFA
.. |..||.| .|.| .|........                       ||.|...|. .    . | ..          ||.| | . .||.|. .| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ--NSSKVYMGFEYVAGGDMAFHLHNLKKFE-----------KHDVRLYIAELAL---------------AIEYIHRNN-IIYRDLKPENILMDETGSV
||  . ...|. .||. |||.  .. | ||..              .. ......                |.||.| .| ||.||.||||||.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLTDFGLVKDIAYS--------------------------------KGAHSFCGTPEYLAPEIIKSQK---------YGPKIDWWALGIVMYSFLYGQTP
|..|||| |..  .                                  ....||||.|.||||....|         |. |.|.|.||...| .|.|..|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

WYDDNMDKLFKKIISAPLEFP-----------------PDATSDE-KDLIKN----LLDRNPETRKD-IRFLLHHPFF
.        ...|.  ...||                 ..  |.| |||||.    .|...|| | . .  .| ||.|
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 88481.m00082.AA MAST 115-261 38 3.2e-57 173.05 In-house 1-150 (337) Show / Hide 
Range on Protein: 115-261
Range on HMM: 1-150/337
Sequence Identity: 38% (57 aa)

FIPINVIGRGYYGKVTLCEKKSTGQRYAIKSVHKSRLMKAHKAITVINERNTLMKTDHPFIVHIYFAFQN--SSKVYMGFEYVAGGDMAFHLHNLK-KFE
|  | .|..| ||.| | ..|.|..|.|.|.  .. ... .   .|. |||.|  .. ||.| .. .||     ...|  ||. ||| |..|...   ..
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

KHDVRLYIAELALAIEYIHRNNIIYRDLKPENILMDETGSVKLTDFGLVK
 . ...||||. |..||.|   |. |||||.|.| | .| .||||||| |
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSK
Kinase 88481.m00082.AA MAST 115-259 42 4.9e-57 182.26 In-house 1-145 (334) Show / Hide 
Range on Protein: 115-259
Range on HMM: 1-145/334
Sequence Identity: 42% (61 aa)

FIPINVIGRGYYGKVTLCEKKSTGQRYAIKSVHKSRLMKAHKAITVINERNTLMKTDHPFIVHIYFAFQNSSKVYMGFEYVAGGDMAFHLHNLKKFEKHD
|  | .|..| |||| | ..|.|..|.|.| . || ... .   .|. |||.|  .. ||.|... .||  ....|  ||. ||| |..||..  |. . 
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

VRLYIAELALAIEYIHRNNIIYRDLKPENILMDETGSVKLTDFGL
...||||..|..||.|.  |. |||||.|.| | .| .|||||||
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGL
Kinase 88481.m00082.AA MAST 273-366 38 1.6e-33 99.28 In-house 229-337 (337) Show / Hide 
Range on Protein: 273-366
Range on HMM: 229-337/337
Sequence Identity: 38% (43 aa)

CGTPEYLAPEIIKSQK-YGPKIDWWALGIVMYSFLYGQTPWYDDNMDK-LFKKIIS--APLEFPPD--------ATSDEKDLIKNLLDRNPETR------
||||.|.|||.|  |  ||. .|||..||.|| || | .|  .|.  . .| .||.    .|.|..         ... .|||| ||. || .|      
CGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLGANGA

KDIRFLLHHPFF
..|     ||||
DEIK---QHPFF
Kinase 88481.m00082.AA MAST 273-354 37 3.8e-32 100.67 In-house 225-318 (334) Show / Hide 
Range on Protein: 273-354
Range on HMM: 225-318/334
Sequence Identity: 37% (35 aa)

CGTPEYLAPEIIKSQK-YGPKIDWWALGIVMYSFLYGQTPWYDDNMDKLFKKIISAP---LEFPPD--------ATSDEKDLIKNLLDRNPETR
||||.|.|||.|. |  .|. .|||..||.|| || | .|  ||. ...| .|..      |.|..         ... .|||..||. .|..|
CGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKR
Kinase 88481.m00082.AA TyrKc 115-366 22 2.8e-15 24.38 SMART 1-280 (280) Show / Hide 
Range on Protein: 115-366
Range on HMM: 1-280/280
Sequence Identity: 22% (65 aa)

FIPINVIGRGYYGKVTLCEKKSTGQRYAIKSVHKSRLMKAHKAITVINERNTLMKT--DHPFIVHIYFAFQNS-------SKVYMGFEYVAGGDMAFHLH
   . ..|.| .|.| ... |   .  |.|.....           ..| . ..|   .|| || .| .   .         ... .||...||   .|.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

NLKK-FEKHDVRLYIAELALAIEYIHRNNIIYRDLKPENILMDETGSVKLTDFGLVKDIAYS------KGAHSF----CGTP----EYLAPEIIKSQKYG
. .. .   |   .    |   ||.|..|.| |||   |.| .| . || .|||| .||         |   .     .|        .||| |.  |. 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

PKIDWWALGIVMY-SFLYGQTPWYD-----DNMDKLFKKIISA-PLEFPPD--------ATSDEKDLIKNLLDRNPETRKDIRFLLHHPFF
.| | |. |..|.  | |||.|...      . . ..... .   .. ||.        ....  ...|   ...|| |   . .  | .|
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 88481.m00082.AA Pkinase_Tyr 115-303 26 9.6e-11 37.01 Pfam 1-205 (270) Show / Hide 
Range on Protein: 115-303
Range on HMM: 1-205/270
Sequence Identity: 26% (54 aa)

FIPINVIGRGYYGKVTLCEKK----STGQRYAIKSVHKSRLMKAH-KAITVINERNTLMKT-DHPFIVHIYFAFQ-NSSK--VYMGFEYVAGGDMAFHLH
 . . ..|.| .|.| ... |    .|..  |.|.. |   |. . .    ..| .....  .|| ||  | .    .    .|. .||...||.  .|.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

N----LKKFEKHDVRLYIAELALAIEYIHRNNIIYRDLKPENILMDETGSVKLTDFGLVKDI----AY-SKGAHSFCGTPEYLAPEIIKSQKYGPKIDWW
.     ...  .|   . .. | . || ...|.| |||   |.| .|.. || .|||| .||     |  |. ..       .||| |.  |.  | | |
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGKFTTKSDVW

ALGIVMY
. |..|.
SFGVLMW
Kinase 88481.m00082.AA S_TK_X 367-427 21 0.000106 16.68 SMART 1-79 (79) Show / Hide 
Range on Protein: 367-427
Range on HMM: 1-79/79
Sequence Identity: 21% (18 aa)

NGIKFKDILQ--RNIPHHYKPDII----QLGAPSNFDHELLDEPILESLATPIHE---------------ESDAFTGFSFDC
 || ......  ..|.  .||.|       .  |||| |  .|..    .||. .               ..| | ||....
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM---LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF