Gene 81529.m00556 (T.vaginalis)

81529.m00556

Species: T.vaginalis
Alias: 81529.m00556, TvagK0267
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
81529.m00556.AA Protein None 995 None Fasta, JSON
81529.m00556.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of 81529.m00556.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 81529.m00556.AA TKL 209-454 28 2.5e-91 309.72 In-house 1-364 (364) Show / Hide 
Range on Protein: 209-454
Range on HMM: 1-364/364
Sequence Identity: 28% (104 aa)

IGTGVSGNVYLGKNKN--------TGEEVAVKILHKKQLSGSELES----------------------YQREVYALSVLV---HPCILKFCGYTEDPP--
|| | .| || || ..        ||..||||...... . ... |                       ..|.. . ..    || |..| ||  .||  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------YYILTEYMANGCLFDILRKRPQILTPTIRSLIALDIARGLEYLHS--------KGVIHRDMKSLNILIDNNYR--------------A
            ..| .||. .|.|...|        .  |  .|||||||..||||        ...|||| || |||.|.|..              .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

RICDFGFVRSKNQATPMTGL--------------------IGTAHWMAPEVLLSSPN---------------YDEKVDVYSYAILLWELLTNEPPFSGMN
 |||||. |...| . |.                      .||  |||||||  ..|               |.||.||||..|.|||.|| ..|.....
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

PSQIT---------DLVINQGYRPPIP------------DNAPPNLTKLINKCWQTDPTKRLSMSKVVRYL
....           .|.. |.|||||            ...|| . ||. .||..||.||.|..... .|
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 81529.m00556.AA MLK 203-454 34 8.3e-90 304.67 In-house 1-291 (291) Show / Hide 
Range on Protein: 203-454
Range on HMM: 1-291/291
Sequence Identity: 34% (99 aa)

FILGKSIGTGVSGNVYLGKNKNTG---EEVAVKILH----KKQLSGSELESYQREVYALSVLVHPC----ILKFCGY-TEDPP-YYILTEYMANGCLFDI
. . . || | .| |..|. .|.     .||||. .     |. ...| .  ..|.. |..| ||     | .| |  ...|. ..|..||...|.|...
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LRKRPQ-------------ILTPTIRSLIALDIARGLEYLHSKG---VIHRDMKSLNILIDN------NYRARICDFGFVRSKNQA-TPMTGLIGTAHWM
|. ..              . ..     .||..|||..||||.    .|||| || |||||.      .  ..||||| .|...|  | |.. .||. ||
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWM

APEVL--LSSPNYDEKVDVYSYAILLWELLTNEPPFS-GMNPSQITDLVINQGYRPPIPDNAPPNLTKLINKCWQTDPTKRLSMSKVVRYL
||||.  . .  |.||.||.|....|||.|| | |.. ...|..|   |.. | ||||| ..|. . ||...||..|| || |.. .| .|
APEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase 81529.m00556.AA Dicty4 198-456 35 2.6e-86 287.87 In-house 1-277 (277) Show / Hide 
Range on Protein: 198-456
Range on HMM: 1-277/277
Sequence Identity: 35% (102 aa)

INRDDFILGKSIGTGVSGNVYLGKNKNTGEEVAVKIL--HKKQLSGSELESYQREVYALSVLVHPCILKFCGY-T----EDPPYYILTEYMANGCLFDIL
||....     ||.|  | ||.|. .  | |||||.|  |.  .. ..|..  .||  .. . || |..| |. |    . .   | ||||  | |. .|
INIEQR-----IGKGSFGEVYKGTWR--GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLL

RK-----RPQILTP--TIRS--LIALDIARGLEYLHSKG--VIHRDMKSLNILIDNNYRARICDFGFVR----SKNQATPMTGLIGTAHWMAPEVLLSSP
..      . |  .  .|..  ..|.|.|||. .||.    .|||| || |.|.| |.|. .||||. .     ... . ... .||. ||||||. . |
HDKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQP

NYDEKVDVYSYAILLWELLTNEPPFS--GMNPSQITDLVINQGYRPPIPDNAPPNLTKLINKCWQTDPTKRLSMSKVVRY--LFD
 |.||.||||..|.|||.|| . |..  .|.. |. ..| | . ||||||. ||....||..|| .||..| |.. .. .  |  
-YNEKADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase 81529.m00556.AA TKL-Unique 205-454 34 8.5e-83 281.38 In-house 1-290 (290) Show / Hide 
Range on Protein: 205-454
Range on HMM: 1-290/290
Sequence Identity: 34% (100 aa)

LGKSIGTGVSGNVYLGKNKNTGEEVAVKILHK-KQLSGSELESYQREVYALSVLV-HPCILKFCGYTE----DPP-YYILTEYMANGCLFDILR------
 ...||.|..|.|| || .  |..||.|..|.   .| ....   .||  ...|  || |... ||.     .|| ..| .||.  | | | |       
FWNKIGEGGYGQVYKGKWR--GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

---KRPQILTPTIRSLIALDIARGLEYLHSKG--VIHRDMKSLNILIDNN-----YRARICDFGFVRSKNQATPMTGL----------IGTAHWMAPEVL
   ..   |..  |  .|.|||.|..|||...  .||||.||.|.|.|||     ....|||||....... . ||            .|.. |||||||
NNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

LSS-PNYDEKVDVYSYAILLWELLTNEP------PFSGMNPSQITDLVIN--QGYRPPIPDNAPPNLTKLINKCWQTDPTKRLSMSKVVRYL
 ..   |.||.||||..| |||..|..       |..||.. |.  .|     .||||||.. |.....||..||  ||..| | . .. .|
RMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase 81529.m00556.AA Pkinase 203-454 29 5.5e-79 273.51 Pfam 1-293 (293) Show / Hide 
Range on Protein: 203-454
Range on HMM: 1-293/293
Sequence Identity: 29% (87 aa)

FILGKSIGTGVSGNVYLGKNKNTGEEVAVKILHKKQLSGSELESYQR--EVYALSVLVHPCILKFCGYTE-DPPYYILTEYMANG----CLFDILR-KRP
. .|. || | .| ||....|.||..|||||. |.  . .....  |  |.. .  | ||.|... .. | .. .|. .||. .|     |||... .| 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

QIL--TPTIRSLIALDIARGLEYLHSKGVIHRDMKSLNILIDNNYRA----RICDFGFVRS--KNQATPMTGLIGTAHWMAPEVLLSSPNYDEKVDVYSY
  .  ..     ... |.|||||.||.|.||||.|. |||||||.      .|||||. .       . ||.. || ..|||||..... |. |||..|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

AILLWELLTNEPPFSGM------NPSQITDLVINQGYRPPIP-------------------DNAPPNLTKLINKCWQTDPTKRLSMSKVVRY--L
 ..|.|.|. .|||.|       .. |. ...    .. ..|                   .|..... ..|..|.. ||.||..   ..    .
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 81529.m00556.AA S_TKc 203-454 30 2.3e-72 247.66 SMART 1-231 (231) Show / Hide 
Range on Protein: 203-454
Range on HMM: 1-231/231
Sequence Identity: 30% (81 aa)

FILGKSIGTGVSGNVYLGKNKNTGEEVAVKILHKKQLSGSELESYQREVYALSVLVHPCILKFCGYTEDPPYYILTEYMAN--GCLFDILRKRPQI----
. ... || |  | ||....|.||..||.||..         |. .||.  |.   || | |. .. .|  .|. .||. .  | |||...||.      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LTPTIRSLIALDIARGLEYLHSKGVIHRDMKSLNILIDNNYRARICDFGFVRSKNQATPMTGLIGTAHWMAPEVLLSSPNYDE-KVDVYSYAILLWELL
 ...     ..  |...|||.||.|.|||| |  |||.|.  .  |||||. |        | ..|| ..||||||     |.  |.|..|  ..|.|.|
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEML

TNEPPFSGMNPSQITDLVINQGYRPPIPDNAPPNLTKLINKCWQTDPTKRLSMSKVVR---------YL
. .|||.  .. .. ...             .| .  .|.||.| ||.||..  .. .         ..
CGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 81529.m00556.AA Pkinase_Tyr 203-454 34 2.2e-67 228.86 Pfam 1-270 (270) Show / Hide 
Range on Protein: 203-454
Range on HMM: 1-270/270
Sequence Identity: 34% (93 aa)

FILGKSIGTGVSGNVYLGKNK----NTGEEVAVKILHKKQLSGSE--LESYQREVYALSVL-VHPCILKFCGYTE--DPP--YYILTEYMANGCLFDILR
 ..|| .| |  |.||.|. |    ||. .||||.| | . . ..  .|.  ||.  .. |  || |... |     . |  .|| .|||..|.| | ||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

KR---PQILTPTIRSLIALDIARGLEYLHSKGVIHRDMKSLNILIDNNYRARICDFGFVRSK---NQA-TPMTGLIGTAHWMAPEVLLSSPNYDEKVDVY
|.   .| ||.     ....||.|.|||.||. ||||    |.|...|  ..|||||  |      .  .  .|      |||||..  .  . .| ||.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK-FTTKSDVW

SYAILLWELLTNE-PP-FSGMNPSQITDLVINQGYRPPIPDNAPPNLTKLINKCWQTDPTKRLSMSKVVRYL
|. .|.||..|    | . || .... ...  .||| |.|.|.|. . .|. .||. || .| ..| ... |
SFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase 81529.m00556.AA Dicty5 204-458 34 1.3e-65 224.34 In-house 2-260 (260) Show / Hide 
Range on Protein: 204-458
Range on HMM: 2-260/260
Sequence Identity: 34% (91 aa)

ILGKSIGTGVSGNVYLGKNKNTGEEVAVKILHKKQLSGSELESYQREVYALSVLV--HPCILKFCG-YTEDPPY-YILTEYMANGCLFDILRKRPQ----
.... |  | || || |  |  |  ||.| .      . ......|||  .|.    || . .. |  . .  | ...|||  || ||. |. .      
SFHDWIASGASGRVYNGIYK--GMDVAIKVYSQENCMCFDWNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQ

-ILTPTIRSLIALDIARGLEYLHSKGVIHRDMKSLNILIDNNYRARICDFGFVRSKNQATPMTGLIGTAHWMAPEVLLSSPNYDEKVDVYSYAILLWELL
 |. ... . .|.|||.....|||...||||.||.|.||  |. . | |||  |    .  ||  .||  |||.|.  . | |..|.||||..| |||..
PIAYFQQLH-MAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFNGQP-YHQKCDVYSFGIVLWEMF

TNEPPFSGMNPSQITDLVINQGYRPPIPDNAPPNLTKLINKCWQTDPTKRLSMSKVVRYLFDPS
|   |.  .|   |  .|   | || ||   |    .|| ||||  | .| |  ... |.   .
TRKEPYDNINNWNIPVMVM-KGERPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII
Kinase 81529.m00556.AA LRRK 203-456 27 1.5e-65 224.11 In-house 1-351 (351) Show / Hide 
Range on Protein: 203-456
Range on HMM: 1-351/351
Sequence Identity: 27% (99 aa)

FILGKSIGTGVSG-NVYLGKNKN--------------------------TGEEVAVKILHKK-----------------------------QLSGSELES
.. ...|| |..| .|| .| ..                           ...||.|....                              |.. . ...
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

YQ---REVYALSVLVHPCILKFCGYTEDPPYYILTEYMANGCLFDILRKRPQ--I------LTPTIRSLIALDIARGLEYLHSKG--VIHRDMKSLNILI
..   .||. .| | ||.|..  |.. . |. . .||. .| | . |... |  .      ......  |||.||.|.|||||.   .|||| || |||.
FREFRHEVWIMSHLNHPNIVSLKGFCIH-PLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILL

---D---------NNYRARICDFGFVRSKNQATPMT---GLIGTAHWMAPEVLLSS--PNYDEKVDVYSYAILLWELLTNE-PPFSGMN-------PSQI
   .         ... | |.|||  |   |...|.   |. |.  |||||..      .|.||||.||....|||||| . .|| ...        .||
WSSPQNHSPNYPNAHVCAKIADFGISR-MFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQI

TDLVINQGYRPPIPDN-APP-----NLTKLINKCWQTDPTKRLSMSKVVRYLFD
 |..|. | ||.|| .  ||      . .||..|||.||.|| ..|..|  | .
EDKIIE-GLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase 81529.m00556.AA Dicty4-Unclassified 205-454 34 1.7e-64 219.81 In-house 3-263 (263) Show / Hide 
Range on Protein: 205-454
Range on HMM: 3-263/263
Sequence Identity: 34% (91 aa)

LGKSIGTGVSGNVYLGKNKNTGEEVAVKILHKKQLSGS--ELESYQREVYALSVLVHPCILKFCGYTEDP-----PYYILTEYMANGCLFDILR------
  . || |    |. |  |  | .||||..   . .     .. . .||  |  . ||  .|  ||   |      . | .| |  | || .        
IDQFIGKGHFSKVHKGNWK--GKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQ

KRPQILTPTIRSLIALDIARGLEYLHSKGVIHRDMKSLNILIDNNYRARICDFGFVRSKNQATPMTGLIGTAHWMAPEVLLSSPNYDEKVDVYSYAILLW
..|  |  |.   .|.|||.|. .||.. .||||.|| |||.| .. ..| |||  |       ||   ||  | .||.|     |  | ||||||..|.
QQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHE-SYNQKSDVYSYAMMLY

ELLTNEPPFSGMN-PSQITDLVINQGYRPPIPDNAPPNLTKLINKCWQTDPTKRLSMSKVVRYL
||.| . |. .   .  .  .|   . || |||| .... |||  ||  || || .| ... ||
ELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase 81529.m00556.AA DRK 203-456 36 2.4e-61 206.51 In-house 1-258 (258) Show / Hide 
Range on Protein: 203-456
Range on HMM: 1-258/258
Sequence Identity: 36% (95 aa)

FILGKSIGTGVSGNVYLGKNKNTGEEVAVKILHKKQLS-GSELESYQREVYALSVLVHPCILKFCGYTEDPP-YYILTEYMANGCLFDILRKRPQILTPT
   |  || |  | |..|     | .|||| |          |   .||.  .. | || |  | |    ||   | .|||  | |  ||      .   
IKIGNRIGRGNYGEVFRGTWR--GTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWP

IRSLIALDIARGLEYLHSKG--VIHRDMKSLNILIDNNYRARICDFGFVR----SKNQATPMTGLIGTAHWMAPEVLLSSPNYDEKVDVYSYAILLWELL
 .  ...|.|.|. |||.    .|||| || | |.| ...  . |||        | . . ||  .||  | ||||| . . | || ||||.|| |||..
LMKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMT-MCGTPCWTAPEVLRNQR-YTEKADVYSFAIVLWECV

TNEPPFSGMNPSQITDLVINQ-GYRPPIPDNAPPNLTKLINKCWQTDPTKRLSMSKVVRYLFD
| . |. ||.. |.    . . | |||.| . ||  ..|.| || .||. | ||  ..  |  
TRQDPYFGMPTFQVV-FSVGRHGMRPPMPQWCPPKYIQLMNDCWNEDPQHRPSMQECLERLEA
Kinase 81529.m00556.AA TK 203-454 17 3.2e-61 203.67 In-house 1-486 (486) Show / Hide 
Range on Protein: 203-454
Range on HMM: 1-486/486
Sequence Identity: 17% (84 aa)

FILGKSIGTGVSG---NVYLGKNKNTG-------------------------EEVAVKILHKK-QLSGSELES--------------YQREVYALS--VL
 .||| .| |  |    ||.|. .. .                         ..||||.|...   |  | .                 .|   ..  ..
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

VHPCILKFCGYTED-------------PPYYILTEYMANGC----LFDILRKRPQ---------------------------------------------
 || |... |.  .             .|..|..|||..|.    | | |||..                                              
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------ILTPTIRSLIALDIARGLEYLHSK------GVIHRDMKSLNILIDNNYR-----------ARICDFG---
                              .||.  .  ....||.|.||||||      ...|||    |.|...|..           ..|.|||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----FVRSKNQATPMTGLIGTAH---------------------------WMAPEVLLSSP--------NYDEKVDVYSYAILLWELLT-N-EPPFSGM
       |  .. .  .   .  .                           |||||.|..           . .| ||.|. .|.||..|   ||.  ||
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

NP---------SQITDLVINQ-------------GYRPPIPDNAP--------------PNLTKLINKCWQTDPTKRLSMSKVVRYL
.           .. ... .              ..|.| |...|              . .  |. .||. || .| ..| ....|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase 81529.m00556.AA STE 203-449 23 3.3e-61 209.67 In-house 1-350 (359) Show / Hide 
Range on Protein: 203-449
Range on HMM: 1-350/359
Sequence Identity: 23% (85 aa)

FILGKSIGTGVSGNVYLGKNKN---------------TGEEVAVKILHKKQLS---------------GSELESYQREVYALSVLV--HPCILKFCGYTE
. . . || | .| ||...|..               ||| .|.|...... .                .|......|.  .. .   || | |. |. .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DPP--------YYILTEYMANGCLFDILR---KRPQILT----------PTIRSLIALDIARG-LEYLHSKGVIHRDMKSLNILIDNNYRARICDFGFVR
.           .|  |||..|.| ||..   .... |.           .. . |. .| .| |.||||...|||| |. |||.     . .||||.  
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

SKNQ-----------------ATPMTGLIGTAHWMAPEVLLS-----SPNYDEKVDVYSYAILLWELLTNEPPFSGMNPS----QITDL----------V
. ..                 .   . ..||  ||||||..      .. ||.|.|..|  ....|..| .||.. |.|     .|..            
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

INQGYRPPIPDNAP-------------------PNLTKLINKCWQTDPTKRLSMSK
|..|  ||.||.                     |..   |||| | || || . |.
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQ
Kinase 81529.m00556.AA TyrKc 203-454 30 1.7e-59 204.91 SMART 1-280 (280) Show / Hide 
Range on Protein: 203-454
Range on HMM: 1-280/280
Sequence Identity: 30% (87 aa)

FILGKSIGTGVSGNVYLGKNKNTGEEVAVKILHKKQLSGSELESYQREVYALSVL--VHPCILKFCGYTED--------PPYYILTEYMANGCLFDILRK
  ||| .| |  | ||.|. |   ..|||| |..       .|   ||   .. |   ||.|... |.  .        .|..|..|||..|.| | |||
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

RPQILTPTIRSLIALDIARGLEYLHSKGVIHRDMKSLNILIDNNYRARICDFGFVRSKNQA--------TPMT----GLI--GTAHWMAPEVLLSSPNYD
.   |..     ....||.| ||||||..||||    |.|...|....|.|||  |             . ..    |        |||||..     . 
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFT

EKVDVYSYAILLWELLTN-EPPFSG-----MNPSQITDLVINQGYRPPIPDN--------APPNLTKLINKCWQTDPTKRLSMSKVVRYL
.| ||.|. ...||..|. ..| .|     |.....  .|  ||||.|.|.|        .|. . ... .||. || .| ..| .....
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVK-QGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF